| stella is a maternal effect gene required for normal early development in mice. | stella is a novel gene specifically expressed in primordial germ cells, oocytes, preimplantation embryos, and pluripotent cells. it encodes a protein with a sap-like domain and a splicing factor motif-like structure, suggesting possible roles in chromosomal organization or rna processing. here, we have investigated the effects of a targeted mutation of stella in mice. we show that while matings between heterozygous animals resulted in the birth of apparently normal stella null offspring, stella- ... | 2003 | 14654002 |
| dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours. | we identified a transcript named 11m2 on the basis of its strong male-specific expression pattern in the developing mouse gonad. 11m2 was found to be expressed by gonad primordial germ cells (pgcs) of both sexes and down-regulated in female pgcs as they enter prophase i of the first meiotic division, similar to the expression of oct4. mouse est analysis revealed expression only in early-stage embryos, embryonic stem cells and pre-meiotic germ cells. 11m2 corresponds to a recently reported gene v ... | 2003 | 14684992 |
| photoperiod effect on bud burst in prunus is phase dependent: significance for early photosynthetic development. | a 16-h photoperiod stimulated bud burst in mature rooted cuttings of prunus avium cv. stella, but not in selfed stella seedlings. however, in a 12-h photoperiod, bud burst occurred earlier in the seedlings than in the mature cuttings. in the 12-h photoperiod, production of polypeptides involved in carbon dioxide fixation and photosynthetic electron transport was higher in seedlings than in mature cuttings, whereas in the 16-h photoperiod, shoot development and polypeptide production were similar ... | 1996 | 14871718 |
| effects of elevated co(2) on growth and chloroplast proteins in prunus avium. | to predict the future carbon sequestering capacity of trees, we need information about the possible acclimatory mechanisms of plant growth and photosynthesis in rising atmospheric co(2) under a variety of environmental conditions. we have, therefore, studied the growth response of a tree species (prunus avium l. stella (wild cherry)) to elevated co(2) and characterized the associated changes in photosynthetic machinery of the leaf tissue. self-pollinated seedlings and mature cuttings (clones) fr ... | 1994 | 14967647 |
| rubisco and pep carboxylase responses to changing irradiance in a brazilian cerrado tree species, qualea grandiflora mart. (vochysiaceae). | the activities of ribulose-1,5-bisphosphate carboxylase-oxygenase, rubisco (e.c. 4.1.1.39) and phosphoenolpyruvate carboxylase, pepc (e.c. 4.1.1.31), and concentrations of protein and chlorophyll were measured in extracts from cotyledons and first leaves of qualea grandiflora mart. (vochysiaceae) seedlings after transfer from high-light (20 days at 320 micro mol m(-2) s(-1), par) to low-light (35 days at 120 micro mol m(-2) s(-1), par) conditions. when tween 20 and glycerol were added to the ext ... | 1994 | 14967711 |
| human stellar, nanog, and gdf3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. | genes required to maintain pluripotency in human embryonic stem (hes) cells are largely unknown, with the exception of oct-4, a homolog of mouse oct-4, which is critical for the establishment of the embryonic inner cell mass and the generation of totipotent mouse embryonic stem (mes) cell lines. in the current study, we identified two genes with expression similar to oct-4, in that they are largely restricted to pluripotent hes cells, premeiotic germ lineage cells, and testicular germ cell tumor ... | 2004 | 14990856 |
| dppa3 / pgc7 / stella is a maternal factor and is not required for germ cell specification in mice. | in mice, germ cells are specified through signalling between layers of cells comprising the primitive embryo. the function of dppa3 (also known as pgc7 or stella), a gene expressed in primordial germ cells at the time of their emergence in gastrulating embryos, is unknown, but a recent study has claimed that it plays a central role in germ cell specification. | 2004 | 15018652 |
| arias-stella reaction of the endocervix: a report of 18 cases with emphasis on its varied histology and differential diagnosis. | we report 18 cases of arias-stella reaction involving the endocervix with an emphasis on histologic features that can be encountered and result in the misdiagnosis of carcinoma. the patients ranged in age from 19 to 44 years. two patients had a history of oral contraceptive use and 15 were pregnant; clinical information was not available in one case. ten lesions presented as cervical polyps, and six were incidental findings in specimens obtained because of cervical dysplasia, dysfunctional uteri ... | 2004 | 15105648 |
| phylogenetic relationships of the genera stella, labrys and angulomicrobium within the 'alphaproteobacteria' and description of angulomicrobium amanitiforme sp. nov. | the unusually shaped bacteria of the genera stella, labrys and angulomicrobium have been described based on their cell morphology and biochemistry. however, their phylogenetic relationships remain unresolved. an earlier study that was based on 5s rrna gene sequences placed the genus stella within the 'alphaproteobacteria'. in the present report, polar lipids and 16s rrna genes of the type strains of the two species in the genus stella, stella humosa dsm 5900(t) and stella vacuolata dsm 5901(t), ... | 2004 | 15143003 |
| endometrial involvement by intra-abdominal diffuse malignant mesothelioma. | a 49-year-old patient presented with an adnexal mass. endometrial curettage showed a proliferative phase and suspicious fragment resembling arias stella reaction. laparotomy revealed an extensive nodular intra-abdominal tumor involving the bilateral ovaries. microscopic findings were similar to the suspicious endometrial fragment in the curettage specimen. histochemical and immunohistochemical studies confirmed the diagnosis of diffuse malignant mesothelioma with metastasis to the endometrium. t ... | 2004 | 15171327 |
| [cloning of compaction-related gene crg1 of mouse preimplantation embryos]. | a total of 181 8-cell embryos and 241 8-cell compacted embryos were collected respectively from c57bl/6 mouse and their cdna was synthesized by smart-pcr. then pcr productions after ssh were cloned into pucm-t vector according to the size after isolated and purified. choice the positive clones for sequencing after being confirmed with pcr. all fragment cloned were blastered matching in genbank for homology analysis. on the base of this work, we select two ests (genbank accession no.: bq740263 an ... | 2004 | 15195562 |
| immunohistochemical staining for ki-67 and p53 helps distinguish endometrial arias-stella reaction from high-grade carcinoma, including clear cell carcinoma. | the distinction of the arias-stella reaction from clear cell carcinoma of the endometrium is usually straightforward; however, this differential diagnosis can be difficult when the arias-stella reaction occurs outside the setting of pregnancy or in older patients. the differential diagnosis also is problematic when serous or clear cell carcinoma focally arises within an endometrial polyp, as part of "endometrial intra-epithelial carcinoma" (eic), or in younger patients. the goal of this study wa ... | 2004 | 15213598 |
| activation-induced cytidine deaminase deaminates 5-methylcytosine in dna and is expressed in pluripotent tissues: implications for epigenetic reprogramming. | dna deaminases of the aid/apobec family convert cytosine into uracil and play key roles in acquired and innate immunity. the epigenetic modification by methylation of cytosine in cpg dinucleotides is also mutagenic, but this is thought to occur by spontaneous deamination. here we show that aid and apobec1 are 5-methylcytosine deaminases resulting in a thymine base opposite a guanine. their action can thus lead to c --> t transition mutations in methylated dna, or in conjunction with repair of th ... | 2004 | 15448152 |
| nematode acetylcholinesterases: molecular forms and their potential role in nematode behavior. | nematode movement is reliant upon the somatic musculature that runs longitudinally along the body wall. neuromuscular synapses occur in the ventral and dorsal cords and employ the excitatory neurotransmitter, acetylcholine (ach), for modulation of muscle activity. acetylcholine activity is terminated by hydrolysis by acetylcholinesterase (ache). here, charles opperman and stella chang discuss the molecular forms and potential role of this enzyme. | 1992 | 15463554 |
| bioactive apocarotenoids annuionones f and g: structural revision of annuionones a, b and e. | the polar bioactive fractions of helianthus annuus cv. stella and sh-222 have yielded eight apocarotenoids, two of them isolated for the first time as natural products (annuionones f and g). the isolation of higher amounts of annuionones a and e allowed us to realize a more comprehensive spectroscopical study. we propose a revised structure for annuionone a, b and e based on careful re-analyses of new spectroscopical data. | 2004 | 15504441 |
| [identifying the s genotypes of sweet cherry (prunus avium l.) cultivars]. | this report identified s-rnase genes (s genes) of sweet cherry (prunus avium l.), presented the sequences of s genes by using a pair of specific primers pruc2 and pruc4r based on the conserved regions c2 and rc4 of rosaceous s-rnase genes and researched the s gene specific products from the genomic dnas of different cultivars in which most of the s genotypese were unknown. the bands of pcr were cloned and their sequences were compared in genbank. four s genes were defined and the conclusion was ... | 2004 | 15552051 |
| insights by peruvian scientists into the pathogenesis of human chronic hypoxic pulmonary hypertension. | pulmonary hypertension had long been suspected in high-altitude natives of the andes. however, it remained for a team of peruvian scientists led by dante penaloza to provide not only the first clear evidence that humans living at high altitude did indeed have chronic, and occasionally severe, pulmonary hypertension, but more importantly, that this was a consequence of structural changes in the pulmonary vascular bed. novel histological findings by one of the team, javier arias-stella, indicated ... | 2005 | 15591308 |
| arias-stella reaction in a cervicovaginal smear of a woman undergoing infertility treatment: a case report. | arias-stella reaction commonly is seen in gestational endometrium, but rarely is described outside the endometrium, particularly in nonpregnant women. although the cytological diagnoses of arias-stella reaction by cervical papanicolaou (pap) smears in pregnant, postpartum, and postabortal women are documented, to our knowledge, this is the first report of arias-stella reaction in a cervicovaginal smear of a nonpregnant woman undergoing infertility treatment with clomiphene and beta-human chorion ... | 2005 | 15637674 |
| multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification. | oct4, nanog, and stella are transcription factors specifically expressed in embryonic stem (es) cells and germ lineage cells that impart critical functions in the maintenance of pluripotency. here, we report the excessive frequency and apparent selectivity of retrotransposition of es cell-specific genes. six highly homologous pseudogenes for oct4, 10 for nanog, and 16 for stella were identified by nucleotide blast (basic local alignment sequence tool) searches against the respective gene mrna tr ... | 2005 | 15640145 |
| forecasting municipal solid waste generation in a fast-growing urban region with system dynamics modeling. | both planning and design of municipal solid waste management systems require accurate prediction of solid waste generation. yet achieving the anticipated prediction accuracy with regard to the generation trends facing many fast-growing regions is quite challenging. the lack of complete historical records of solid waste quantity and quality due to insufficient budget and unavailable management capacity has resulted in a situation that makes the long-term system planning and/or short-term expansio ... | 2005 | 16009300 |
| high numbers of prosthecate bacteria in pulp mill waste aeration lagoons. | prosthecate bacteria comprised 0.6 to 10.5% of the bacterial community in samples from 11 pulp mill waste aeration lagoons. because of their distinct morphology, the genera ancalomicrobium, caulobacter, prosthecobacter, prosthecomicrobium, stella, and hyphomicrobium or hyphomonas could be identified and enumerated by direct microscopic examination. monthly samples from one lagoon showed that several genera varied from undetectable to predominant among the appendaged organisms. temperature (seaso ... | 1979 | 16345371 |
| mass balance assessment for mercury in lake champlain. | a mass balance model for mercury in lake champlain was developed in an effort to understand the sources, inventories, concentrations, and effects of mercury (hg) contamination in the lake ecosystem. to construct the mass balance model, air, water, and sediment were sampled as a part of this project and other research/monitoring projects in the lake champlain basin. this project produced a stella-based computer model and quantitative apportionments of the principal input and output pathways of hg ... | 2006 | 16433336 |
| the cover. new madrid. | | 2006 | 16403917 |
| dazl deficiency leads to embryonic arrest of germ cell development in xy c57bl/6 mice. | genes of the daz family play critical roles in germ cell development in mammals and other animals. in mice, dazl mrna is first observed at embryonic day 11.5 (e11.5), but previous studies using dazl-deficient mice of mixed genetic background have largely emphasized postnatal spermatogenic defects. using an inbred c57bl/6 background, we show that dazl is required for embryonic development and survival of xy germ cells. by e14.5, expression of germ cell markers (mvh, oct4, dppa3/stella, gcna and m ... | 2005 | 16310179 |
| sesquiterpene lactones as allelochemicals. | six new sesquiterpene lactones, annuolide h (3), helivypolides f, h-j (4, 11-13), and helieudesmanolide a (6), together with known compounds, were isolated from polar bioactive fractions of helianthus annuus cv. sh-222 and stella fresh leaf water extracts. spectroscopic analysis of the new data for 1,2-anhydroniveusin a and 1-methoxy-4,5-dihydroniveusin a corrects some previous assignments. the compounds were tested using the etiolated wheat coleoptile bioassay, and the most active compounds wer ... | 2006 | 16724843 |
| adult tissue-specific expression of a dppa3-derived retrogene represents a postnatal transcript of pluripotent cell origin. | processed pseudogenes emerge by reverse transcription of spliced mrnas followed by incorporation of the resultant cdna into the genome. their genesis requires that retrotransposition occurs within the germ line, a provision that significantly limits random distribution of source genes. we previously identified embryonic stem cell-specific genes as an enriched source of retropseudogene origin. nanog, oct4, and dppa3 (stella/pgc7) presented as source genes for >30 processed pseudogenes within the ... | 2006 | 16291741 |
| gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling. | germ cell fate in mice is induced in proximal epiblast cells at embryonic day (e) 6.5 by signaling molecules. prdm1(also known as blimp1)-positive lineage-restricted precursors of primordial germ cells (pgcs) initiate the formation of a cluster that differentiates into dppa3 (also known as stella)-positive pgcs from around e7.0 onwards in the extra-embryonic mesoderm. around e7.5, these pgcs begin migrating towards the definitive endoderm, with concomitant extensive epigenetic reprogramming. to ... | 2006 | 16870942 |
| retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity. | testicular germ cell tumors (tgcts) are the most common carcinomas of young men aged 15-35. the molecular events involved in tgct genesis are poorly understood. tgcts have near universal amplification of the short arm of chromosome 12, however positional cloning efforts have not identified causative genes on 12p involved in formation or progression of tgcts. human embryonal carcinoma (ec) are the stem cells of tgcts and are pluripotent. ec cells terminally differentiate toward a neuronal lineage ... | 2005 | 16168501 |
| orphan nuclear receptor gcnf is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. | embryonic stem (es) cell pluripotency and differentiation are controlled by a network of transcription factors and signaling molecules. transcription factors such as oct4 and nanog are required for self-renewal and maintain the undifferentiated state of es cells. decreases in the expression of these factors indicate the initiation of differentiation of es cells. inactivation of the gene encoding the orphan nuclear receptor gcnf showed that it plays an important role in the repression of oct4 exp ... | 2005 | 16166633 |
| experiments with mathematical models to simulate hepatitis a population dynamics under different levels of endemicity. | heterogeneous access to sanitation services is a characteristic of communities in brazil. this heterogeneity leads to different patterns of hepatitis a endemicity: areas with low infection rates have higher probability of outbreaks, and areas with higher infection rates have high prevalence and low risk of outbreaks. here we develop a mathematical model to study the effect of variable exposure to infection on the epidemiological dynamics of hepatitis a. differential equations were used to simula ... | 2005 | 16158159 |
| chloride concentration affects kv channel voltage-gating kinetics: importance of experimental anion concentrations. | chloride concentration has been shown to have a dramatic impact on protein folding and subsequent tertiary conformation [k.d. collins, ions from the hofmeister series and osmolytes: effects on proteins in solution and in the crystallization process, methods 34 (2004) 300-311; i. jelesarov, e. durr, r.m. thomas, h.r. bosshard, salt effects on hydrophobic interaction and charge screening in the folding of a negatively charged peptide to a coiled coil (leucine zipper), biochemistry 37 (1998) 7539-7 ... | 2005 | 16140173 |
| simulating fibrin clotting time. | the clotting time (ct) of fibrinogen mixed with thrombin decreased, then increased with increasing fibrinogen levels. by contrast, log ct decreased monotonically with respect to the log level of activating enzyme (thrombin or reptilase). here, the ct was determined over a large range of fibrinogen concentration (to 100 mg ml(-1)) at a fixed level of enzyme. a new parameter, [fib]min, the minimal fibrinogen concentration required for thrombin or reptilase-instigated phase change (coagulation), wa ... | 2006 | 16929924 |
| testicular cell conditioned medium supports differentiation of embryonic stem cells into ovarian structures containing oocytes. | previous reports and the current study have found that germ cell precursor cells appear in embryoid bodies (ebs) formed from mouse embryonic stem cells as identified by positive expression of specific germ cell markers such as oct-3/4, mvh, c-kit, stella, and dazl. we hypothesized that if exposed to appropriate growth factors, the germ cell precursor cells within the ebs would differentiate into gametes. the source for growth factors used in the present study is conditioned medium collected from ... | 2006 | 16109761 |
| comparative analysis of development-related gene expression in mouse preimplantation embryos with different developmental potential. | the potential of embryonic and somatic cell nuclear-transferred (nt) mouse oocytes to develop into young is low compared with bovine nt oocytes. to examine the reasons for the low developmental potential of nt mouse oocytes, we analyzed the gene expression patterns of six development-related genes (oct4, nanog, stat3, stella, fgf4, and sox2) during preimplantation development in manipulated oocytes with different potentials to develop into young using real-time polymerase chain reaction (pcr) me ... | 2005 | 16013066 |
| nanog expression in mouse germ cell development. | nanog is a newly identified transcriptional factor bearing a homeodomain and expressed in pluripotential cells of preimplantation and early postimplantation embryos, and embryonic stem (es) and embryonic germ (eg) cells. knockout experiments indicate that nanog functions as a key player in maintaining the pluripotency of stem cells. importantly, nanog expression is highly expressed in primordial germ cells (pgcs) of e11.5 and e12.5 mouse embryos. however, its temporal and spatial expression patt ... | 2005 | 15939376 |
| differentiation of embryonic stem cells after transplantation into peritoneal cavity of irradiated mice and expression of specific germ cell genes in pluripotent cells. | permanent embryonic stem cell lines (es cells) are considered as one of the most promising cellular sources for regenerative medicine. es cells have a high proliferative potency and ability to differentiate into all kinds of somatic and germ cells. however, transplantation of undifferentiated es cells into adult recipient tissue results in the formation of teratomas. to understand the mechanisms underlying self-renewal and determination of pluripotent cells, we investigated differentiation poten ... | 2005 | 15808624 |
| stella research software for teaching concepts of nutrient dynamics in the undergraduate classroom. | | 2003 | 14995050 |
| the arias-stella reaction: a nonspecific involutional phenomenon in intra- as well as extrauterine pregnancy. | | 1965 | 14287790 |
| [diagnostic value of the arias stella sign in ectopic pregnancy. clinical and experimental study]. | | 1962 | 13935973 |
| [the so-called arias-stella "syndrome"]. | | 1962 | 13892530 |
| [on some unusual aspects of the pregnant endometrium. arias-stella test and clear cells]. | | 1960 | 13732594 |
| a simulation study of the genetic regulatory hierarchy for butterfly eyespot focus determination. | the color patterns on the wings of butterflies have been an important model system in evolutionary developmental biology. two types of models have been used to study these patterns. the first type of model employs computational techniques and generalized mechanisms of pattern formation to make predictions about how color patterns will vary as parameters of the model are changed. these generalized mechanisms include diffusion gradient, reaction-diffusion, lateral inhibition, and threshold respons ... | 2006 | 16686638 |
| derivation of male germ cells from bone marrow stem cells. | recent studies have demonstrated that somatic stem cells have a more flexible potential than expected, whether put into tissue or cultured under different conditions. bone marrow (bm)-derived stem cells can transdifferentiate into multilineage cells, such as muscle of mesoderm, lung and liver of endoderm, and brain and skin of ectoderm origin. here we show that bm stem cells are able to transdifferentiate into male germ cells. for derivation of male germ cells from adult bm stem (bms) cells, we ... | 2006 | 16652109 |
| ppv long-distance movement is occasionally permitted in resistant apricot hosts. | the interactions between plum pox virus (ppv), a member of the potyvirus genus, and prunus host plants are, up to now, poorly understood. in the current paper, fluorescence stereomicroscopy, in situ hybridisation and immunogold detection were performed in order to evaluate the virus transport and cellular distribution. the behavior of ppv in several susceptible (cv. "moniqui" and "screara") and resistant apricot genotypes (cv. "harlayne", "henderson", "harcot", "goldrich", "stella" and "stark ea ... | 2006 | 16504333 |
| two-stage coarsening mechanism in a kinetically constrained model of an attractive colloid. | we study an attractive version of the east model using the real-space renormalization group (rg) introduced by stella et al. the former is a kinetically constrained model with an ising-like interaction between excitations and shows striking agreement with the phenomonology of attractive colloidal systems. we find that the rg predicts two nonuniversal dynamic exponents, which suggests that in the out-of-equilibrium regime the model coarsens via a two-stage mechanism. we explain this mechanism phy ... | 2006 | 16486224 |
| simulating uptake and transport of tnt by plants using stella. | understanding the uptake and transport of soil organic contaminants by plants is crucial to a successful application of phytoremediation technique. this study investigated the removal of 2,4,6-trinitrotoluene (tnt) from a contaminated sandy soil by a poplar tree (populus fastigiata) through the examinations of temporal variations of xylem water potential, leaf water transpiration, and root water and tnt uptake. a dynamic model for uptake and translocation of contaminants from a soil-plant ecosys ... | 2007 | 17655913 |
| inverse free electron lasers and laser wakefield acceleration driven by co2 lasers. | the staged electron laser acceleration (stella) experiment demonstrated staging between two laser-driven devices, high trapping efficiency of microbunches within the accelerating field and narrow energy spread during laser acceleration. these are important for practical laser-driven accelerators. stella used inverse free electron lasers, which were chosen primarily for convenience. nevertheless, the stella approach can be applied to other laser acceleration methods, in particular, laser-driven p ... | 2006 | 16483952 |
| generation of stella-gfp transgenic mice: a novel tool to study germ cell development. | the relationship between germ cells and pluripotent embryonic stem (es) cells is of particular interest, together with approaches to generate primordial germ cell (pgcs) from es cells. a critical requirement in these experiments is the ability to unambiguously detect pgcs with the use of, for example, reporter genes. the currently available transgenic reporters do not show exclusive expression in pgcs at their earliest developmental stages. here we describe the use of germline-restricted express ... | 2006 | 16437550 |
| down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors. | adult male germ cell tumors (gcts) comprise distinct groups: seminomas and nonseminomas, which include pluripotent embryonal carcinomas as well as other histologic subtypes exhibiting various stages of differentiation. almost all gcts show 12p gain, but the target genes have not been clearly defined. to identify 12p target genes, we examined affymetrix (santa clara, ca) u133a+b microarray ( approximately 83% coverage of 12p genes) expression profiles of 17 seminomas, 84 nonseminoma gcts, and 5 n ... | 2006 | 16424014 |
| cardenolides from saussurea stella with cytotoxicity toward cancer cells. | three new cardenolides, 3-o-beta-d-fucopyranosylstrophanthidin (1), 3-o-beta-d-quinovopyranosylperiplogenin (2), and 3-o-beta-d-glucopyranosyl-(1 --> 4)-alpha- l-rhamnopyranosylcannogenin (3), together with seven known cardenolides (4- 10), were isolated from a cytotoxic ethanol extract of the whole dried plants of saussurea stella. the structures of these compounds were established by spectroscopic and chemical methods. when the cytotoxicity of compounds 2- 10 toward bel-7402 human hepatoma cel ... | 2007 | 17844995 |
| etiologic yield of autistic spectrum disorders: a prospective study. | studies addressing etiologic yield in childhood developmental disabilities have mainly looked at individuals with developmental delay/mental retardation. the few studies addressing the question of etiologic yield in patients with pervasive developmental disorders (pdds) had a major drawback, in that the enrolled subjects were diagnosed as having the autistic spectrum disorders based only on history and clinical examination, and/or on unspecified instruments. in addition, only some of these patie ... | 2006 | 16419094 |
| mitochondrial phylogeny of african wood mice, genus hylomyscus (rodentia, muridae): implications for their taxonomy and biogeography. | this paper investigates the usefulness of two mitochondrial genes (16s rrna and cytochrome b) to solve taxonomical difficulties within the genus hylomyscus and to infer its evolutionary history. both genes proved to be suitable molecular markers for diagnosis of hylomyscus species. nevertheless the resolving powers of these two genes differ, and with both markers (either analyzed singly or in combination), some nodes remain unresolved. this is probably related to the fact that the species emerge ... | 2006 | 16414288 |
| the fg syndrome: report of a large italian series. | initially described as a rare mca/mr syndrome occurring only in boys, due to a recessive mutation on the x chromosome [opitz and kaveggia, 1974], the fg syndrome (fgs) now emerges as a more common disorder also occurring in girls. based on over 50 reported cases, fgs is associated with developmental delay (especially speech), hypotonia, postnatal onset relative macrocephaly, prominent forehead, frontal hair upsweep, telecanthus, or ocular hypertelorism, thin vermilion border of the upper lip, re ... | 2006 | 16691600 |
| [professor's stella niemierko 100th birthday]. | | 2006 | 16869295 |
| smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels. | smad5 is an intracellular mediator of bone morphogenetic protein (bmp) signalling. it is essential for primordial germ cell (pgc) development, for the development of the allantois and for amnion closure, as demonstrated by loss of bmp signalling. by contrast, the appearance of ectopic pgc-like cells and regionalized ectopic vasculogenesis and haematopoiesis in thickened smad5(m1/m1) amnion are amnion defects that have not been associated with loss of bmp signalling components. we show that defec ... | 2006 | 16887830 |
| the effects of dialysis on 131i kinetics and dosimetry in thyroid cancer patients--a pharmacokinetic model. | currently, an accepted post-surgical treatment of patients with thyroid carcinoma is administration of an ablative dose of i. this treatment is well established based on extensive experience and modeling. however, for patients with renal disease, reduced iodine removal rates result in controversial thyroid doses and potentially excessive red bone marrow doses. there are differences of opinion regarding i dose recommendations ranging from a reduction in dose to an increase in dose compared with c ... | 2006 | 16891898 |
| green's function study of the one-electron and shake-up ionization spectra of unsaturated hydrocarbon cage compounds. | the valence one-electron and shake-up ionization spectra of stella-2,6-diene, stella-2,6-dione, bicyclo-[2.2.2]-octane-2,5-dione, and bicyclo-[2.2.1]-heptane-2,5-dione have been exhaustively studied, up to the double ionization threshold and beyond, by means of one-particle green's function theory. this study is based on calculations employing the outer-valence green's function and the third-order algebraic diagrammatic construction schemes, along with a variety of basis sets. a comparison is ma ... | 2006 | 16903000 |
| [dementia: the importance of psychosocial interventions]. | the number of people suffering from dementia in the netherlands is expected to rise from 175,000 in 2006 to 400,000 by the year 2050. stella braam recently wrote a book in which she described the experiences of her father, a former psychologist with the attitudes and knowledge of professionals concerning communication and coping with dementia, when he became dement himself. she reports that hardly anyone actually listened to the emotions and wishes of her father. coping with dementia constitutes ... | 2006 | 16922349 |
| neuropsychological deficits and neural dysfunction in familial dyslexia. | we report the neuropsychological profile and the pattern of brain activity during reading tasks in a sample of familial dyslexics. we studied our subjects with an in-depth neuropsychological assessment and with functional neuroimaging (fmri) during word and pseudoword reading and false font string observations (baseline condition). the neuropsychological assessment revealed that familial dyslexia, in both persistent and compensated forms, is often associated with deficits in verbal short-term me ... | 2006 | 16934234 |
| evidence for complete denitrification in a benthic foraminifer. | benthic foraminifera are unicellular eukaryotes found abundantly in many types of marine sediments. many species survive and possibly reproduce in anoxic habitats, but sustainable anaerobic metabolism has not been previously described. here we demonstrate that the foraminifer globobulimina pseudospinescens accumulates intracellular nitrate stores and that these can be respired to dinitrogen gas. the amounts of nitrate detected are estimated to be sufficient to support respiration for over a mont ... | 2006 | 16957731 |
| the ability of two commercially available quick test kits to detect drug-facilitated sexual assault drugs in beverages. | assessment of the sensitivity and specificity of two commercially available 'drug-facilitated sexual assault' drug detector kits, drink guard and drink detective. | 2006 | 16968342 |
| comparative studies on the mrna expression of development-related genes in an individual mouse blastocyst with different developmental potential. | the evaluation of embryo morphology, widely used for selecting mammalian embryos before transfer, is not an adequate standard for selecting nuclear-transferred (nt) embryos. to search for markers useful for predicting the potential of nt embryos to develop into young, we examined the relation between the morphology of embryos with different developmental potential and gene expression of oct 4, nanog, stat3, fgf4, stella, and sox2. in the present study, we examined pronuclear-exchanged blastocyst ... | 2006 | 17009897 |
| derivation, characterization and differentiation of human embryonic stem cells: comparing serum-containing versus serum-free media and evidence of germ cell differentiation. | this study was designed to establish human embryonic stem cell (hesc) lines, to identify the differences when maintained in serum-containing versus serum-free medium and to test their potential of in vitro differentiation. | 2007 | 17071820 |
| comments on "elimination of 10 polybrominated diphenyl ether (pbde) congeners and selected polychlorinated biphenyls from the freshwater mussel, elliptio complanata" by ken g. drouillard, stella chan, sarah o'rourke, g. douglas haffner, robert j. letcher [chemosphere 69(3) (2007) 362-370]. | | 2008 | 18400246 |
| pgc7/stella protects against dna demethylation in early embryogenesis. | dna methylation is an important means of epigenetic gene regulation and must be carefully controlled as a prerequisite for normal early embryogenesis. although global demethylation occurs soon after fertilization, it is not evenly distributed throughout the genome. genomic imprinting and epigenetic asymmetry between parental genomes, that is, delayed demethylation of the maternal genome after fertilization, are clear examples of the functional importance of dna methylation. here, we show that pg ... | 2007 | 17143267 |
| glutathione transferases sequester toxic dinitrosyl-iron complexes in cells. a protection mechanism against excess nitric oxide. | it is now well established that exposure of cells and tissues to nitric oxide leads to the formation of a dinitrosyl-iron complex bound to intracellular proteins, but little is known about how the complex is formed, the identity of the proteins, and the physiological role of this process. by using epr spectroscopy and enzyme activity measurements to study the mechanism in hepatocytes, we here identify the complex as a dinitrosyl-diglutathionyl-iron complex (dndgic) bound to alpha class glutathio ... | 2007 | 17197702 |
| blanche, stella, tennessee and rose: the sibling relationship in a streetcar named desire. | tennessee williams's guilty and loving relationship with his sister rose haunted his life and influenced his writing. this paper explores that complex sibling relationship and williams's attempt to both give voice to and resolve his conflicts over rose through the writing of a streetcar named desire. | 2006 | 17370467 |
| factor structure evaluation of the childhood autism rating scale. | this study investigated the factor structure of the childhood autism rating scale (cars). principal components analysis (pca) and principal axis factor analysis (paf) evaluated archival data from children presenting to a university clinic with suspected autism spectrum disorders (asds; n = 164). pca did not replicate components identified by dilalla and rogers (1994, domains of the childhood autism rating scale: relevance for diagnosis and treatment. journal of autism and developmental disorders ... | 2007 | 17437070 |
| putative human male germ cells from bone marrow stem cells. | germ cells must develop along distinct male or female paths to produce the spermatozoa or oocyte required for sexual reproduction. male germline stem cells maintain spermatogenesis in the postnatal human testis. here we show that a small population of bone marrow cells is able to transdifferentiate to male germ cell-like cells. we show expression of early germ cell markers (oct4, fragilis, stella and vasa) and male germ cell specific markers (dazl, tspy, piwil2 and stra8) in these cells. our pre ... | 2007 | 17566262 |
| an open multicenter phase ii trial of docetaxel-gemcitabine in charlson score and performance status (ps) selected elderly patients with stage iiib pleura/iv non-small-cell lung cancer (nsclc): the gfpc 02-02a study. | the aim of this study was to determine the impact of patient selection based on age, comorbidity and performance status on the efficacy of platinum-free combination therapy on non-small-cell lung cancer after 65 years of age. we analyzed the overall response rate, the median survival time, the 1-year survival rate, toxicity and quality of life after one to three 6-week cycles of docetaxel 30mg/m(2) weekly and gemcitabine 900mg/m(2) at weeks 1, 2, 4 and 5. fifty patients (median age 73.7 years) w ... | 2007 | 17669664 |
| subcommittee fails to recommend legal reforms needed to promote human rights of sex workers. | in december 2006, the house of commons subcommittee on solicitation laws released its longawaited report on the criminal laws related to prostitution in canada, entitled the challenge of change: a study of canada's criminal prostitution laws. the subcommittee's report fails to call for amendments to the criminal code provisions which have been demonstrated to increase the health and safety threats faced by sex workers. the canadian hiv/aids legal network and two sex worker organizations, stella ... | 2007 | 17715519 |
| [coupled evolution of digestive, respiratory, circulatory, and excretory systems: a model investigation]. | a model is developed of evolution of an organism with digestive, respiratory, circulatory, and excretory systems at the single system. the model is realized on the basis of the language stella 8.0. a balance is found between perfection of each individual physiological system and necessary energy expenditures for survival of the organism as a whole. the model is based on a coupled development of several visceral systems. there is analyzed effect of a change of consumption of substances with food ... | 2007 | 17725033 |
| modeling the mechanisms for uptake and translocation of dioxane in a soil-plant ecosystem with stella. | knowledge of mechanisms for uptake, translocation, and accumulation of soil contaminants in plants is essential to successful applications of the phytoremediation technique. analysis and evaluation of these mechanisms would be greatly facilitated by the availability of a dynamic model that can predict soil contaminant uptake by roots, transport from roots through stems to leaves, and accumulation in plant during the transport process. in this study, a dynamic model for uptake and translocation o ... | 2008 | 17870205 |
| clinical implications of dsm-iv subtyping of bipolar disorders in referred children and adolescents. | according to dsm-iv, bipolar disorders (bds) include four subtypes, bd i, bd ii, cyclothymic disorder, and bd not otherwise specified (nos). we explore the clinical implications of this subtyping in a naturalistic sample of referred youths with bd i, bd ii, and bd-nos. | 2007 | 17885571 |
| pu.1 (sfpi1), a pleiotropic regulator expressed from the first embryonic stages with a crucial function in germinal progenitors. | in the adult mammalian testis, spermatogenic differentiation starts from a minute population of spermatogonial stem cells (sscs). sscs are generated after birth from the fetal gonocytes, themselves derived from the primordial germ cells (pgcs), which are specified during the first days after implantation. transcriptome profiling of purified preparations evidenced the preferential accumulation in sscs of transcripts of pu.1 (sfpi1), a regulatory gene previously identified in hematopoietic progeni ... | 2007 | 17913791 |
| rehabilitation of severely atrophic maxillae with fixed implant-supported prostheses using zygomatic implants placed using the sinus slot technique: clinical report on a series of 21 patients. | the purpose of this article is to describe the management of patients with extreme maxillary atrophy. their treatment consisted of maxillary fixed prostheses supported by conventional implants placed in residual anatomic structures in conjunction with zygomatic implants positioned using the sinus slot technique of stella and warner. | 2007 | 17929527 |
| star-burst prisms with cyclotriveratrylene-type ligands: a [pd6l8]12+ stella octangular structure. | | 2007 | 17960548 |
| isolation of three stem cell lines from human sacrococcygeal teratomas. | sacrococcygeal teratomas (scts) are benign tumours of the newborn with absolute indication for surgery directly after birth. we recently described the presence of stem cells positive for the stem cell markers nanog and oct4 in scts. here we report the isolation of three stem cell lines from three different scts. cells were propagated in mesenchymal or in embryonic stem cell medium. non-clonal homogeneous stem cell lines were obtained after two to three passages and characterized in vitro by immu ... | 2009 | 19142973 |
| differential regulation of abundance and deadenylation of maternal transcripts during bovine oocyte maturation in vitro and in vivo. | in bovine maturing oocytes and cleavage stage embryos, gene expression is mostly controlled at the post-transcriptional level, through degradation and deadenylation/polyadenylation. we have investigated how post transcriptional control of maternal transcripts was affected during in vitro and in vivo maturation, as a model of differential developmental competence. | 2007 | 17988387 |
| functional analysis of a ring domain ankyrin repeat protein that is highly expressed during flower senescence. | a gene encoding a ring zinc finger ankyrin repeat protein (mjxb3), a putative e3 ubiquitin ligase, is highly expressed in petals of senescing four o'clock (mirabilis jalapa) flowers, increasing >40,000-fold during the onset of visible senescence. the gene has homologues in many other species, and the petunia homologue is strongly up-regulated in senescing petunia corollas. silencing the expression of this gene in petunia, using virus-induced gene silencing, resulted in a 2 d extension in flower ... | 2007 | 18057040 |
| proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors. | the extraembryonic tissues, visceral endoderm (ve) and extraembryonic ectoderm (exe) are known to be important for the induction of primordial germ cells (pgcs) in mice via activation of the bone morphogenetic protein (bmp) signalling pathway. we investigated whether the ve and exe have a direct role in the specification of pgcs, or in an earlier event, namely the induction of the pgc precursors in the proximal posterior epiblast cells. | 2007 | 18096072 |
| in vitro differentiation of male mouse embryonic stem cells into both presumptive sperm cells and oocytes. | pioneer work in male mouse embryonic stem (es) cells differentiation into germ cells (gc) showed generations of male or female gametes in separate experiments, using genetically manipulated or preselected es cells. in an attempt to produce both types of gametes from male mouse es cells without any genetic manipulation or preselection, we induce the differentiation by retinoic acid (ra) within nonadherent embryoid bodies (eb). it seems that gamete-like cell formation occurs in the correct manner ... | 2007 | 18154514 |
| an in situ hybridization-based screen for heterogeneously expressed genes in mouse es cells. | we previously reported that zscan4 showed heterogeneous expression patterns in mouse embryonic stem (es) cells. to identify genes that show similar expression patterns, we carried out high-throughput in situ hybridization assays on es cell cultures for 244 genes. most of the genes are involved in transcriptional regulation, and were selected using microarray-based comparisons of gene expression profiles in es and embryonal carcinoma (ec) cells versus differentiated cell types. pou5f1 (oct4, oct3 ... | 2008 | 18178135 |
| system dynamic modeling: an alternative method for budgeting. | to construct, validate, and simulate a system dynamic financial model and compare it against the conventional method. | 2008 | 18387055 |
| mrna expression analysis and the molecular basis of neonatal testis defects in dmrt1 mutant mice. | transcriptional regulators containing the dm domain dna binding motif have been found to control sexual differentiation in a diverse group of metazoan animals including vertebrates, insects, and nematodes, suggesting that these proteins may comprise a very ancient group of sexual regulators. dmrt1, 1 of 7 mammalian dm domain genes, is essential for several aspects of testicular differentiation in mice. the dmrt1 mutant phenotype becomes apparent shortly after birth, and culminates in severe test ... | 2007 | 18391515 |
| a new geometrical description of entanglement and the curative homeopathic process. | the memory of water, a "local" explanation of homeopathy's efficacy, has been supplemented recently by complementary "nonlocal" hypotheses. one of these envisages "quantum macro-entanglement" among patient, practitioner, and remedy to form a "ppr" entangled state, from which the possibility of cure may manifest. | 2008 | 18399761 |
| the origins of acts of love: a discussion of 'break point ' by stella m. yardino. | | 2008 | 18405281 |
| contemporary practices in lakota healthcare. | this article provides strategies for health care delivery for the oglala lakota on the pine ridge reservation of south dakota. | 2008 | 18475237 |
| arias-stella reaction in upper genital tract in pregnant and non-pregnant women: a study of 120 randomly selected cases. | 1. to study the diagnostic importance of the arias-stella reaction. 2. to study tubal epithelial changes in ectopic pregnancy. 3. to study the occurrence of arias-stella reaction in non-pregnant women receiving hormonal treatment. | 2007 | 17219163 |
| arias-stella reaction in an adenomyomatous polyp of the uterus. | we describe a rare case of an arias-stella reaction in an adenomyomatous polyp of the endometrium found in the first trimester of pregnancy. a 33-year-old japanese woman, gravida 1, para 1, presented for an initial prenatal examination at 6-week gestation; ultrasound revealed a myoma-like solid mass in the cervical canal. an abnormal papanicolaou's smear (highly suspicious of adenocarcinoma) prompted the resection of this pedunculated polyp. histologically, the musculature located in the center ... | 2007 | 17230300 |
| a system dynamics approach for hospital waste management. | healthcare services provided by hospitals may generate some infectious wastes. although a large percentage of hospital waste is classified as general waste, which has similar nature as that of municipal solid waste and, therefore, could be disposed in municipal landfills, a small portion of infectious waste has to be managed in the proper manner in order to minimize risk to public health. many factors involved in the hospital waste management system often link to one another, which require a com ... | 2008 | 17368013 |
| a comprehensive, non-invasive visualization of primordial germ cell development in mice by the prdm1-mvenus and dppa3-ecfp double transgenic reporter. | the ability to monitor the development of a given cell lineage in a non-invasive manner by fluorescent markers both in vivo and in vitro provides a great advantage for the analysis of the lineage of interest. to date, a number of transgenic or knock-in mouse strains, in which developing germ cells are marked with fluorescent reporters, have been generated. we here describe a novel double transgenic reporter mouse strain that expresses membrane-targeted venus (mvenus), a brighter variant of yello ... | 2008 | 18583473 |
| [marcus barros talks about the environment and tropical diseases in the amazon. interview by stella oswaldo cruz penido. introduction by ruth b. martins]. | marcus barros talks about how tropical diseases influenced his decision to study medicine. he tells a number of stories about his family, which moved from alto juruá to manaus to escape malaria and other fevers. he says it is essential to adopt homeopathy, acupuncture, and other indigenous knowledge and practices in treating disease. barros also talks about measures taken when he was president of brazil's national environmental institute, instituto brasileiro do meio ambiente e dos recursos natu ... | 2007 | 18783153 |
| mathematical modeling of cadmium removal in free water surface constructed wetlands. | a mathematical model was developed for the cadmium removal process in the free water surface (fws) constructed wetlands using a dynamic software program stella. earlier, laboratory-scale experiments were conducted at the suranaree university of technology campus in northeastern thailand to investigate the effect of high cadmium loading on the performance of fws constructed wetlands under different environmental conditions. the predicted values of cadmium concentrations in effluents as well as in ... | 2009 | 18790567 |
| maternal oct-4 is a potential key regulator of the developmental competence of mouse oocytes. | the maternal contribution of transcripts and proteins supplied to the zygote is crucial for the progression from a gametic to an embryonic control of preimplantation development. here we compared the transcriptional profiles of two types of mouse mii oocytes, one which is developmentally competent (miisn oocyte), the other that ceases development at the 2-cell stage (miinsn oocyte), with the aim of identifying genes and gene expression networks whose misregulated expression would contribute to a ... | 2008 | 18837968 |
| simultaneous bilateral tubal pregnancy after in vitro fertilization and embryo transfer. | ectopic pregnancies are known to occur with increased frequency after in vitro fertilization (ivf) and related techniques. we present a case of bilateral tubal pregnancy following ivf and embryo transfer (et). | 2008 | 18936001 |
| dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. | embryonic stem cells (escs) are apparently homogeneous self-renewing cells, but we observed heterogeneous expression of stella in escs, which is a marker of pluripotency and germ cells. here we show that, whereas stella-positive escs were like the inner cell mass (icm), stella-negative cells were like the epiblast cells. these states were interchangeable, which reflects the metastability and plasticity of escs. the established equilibrium was skewed reversibly in the absence of signals from feed ... | 2008 | 18940731 |
| four new species of emericella from the mediterranean region of europe. | four new species of emericella, e. discophora, e. filifera, e. olivicola and e. stella-maris, are proposed. their new taxonomic status was determined applying a polyphasic taxonomic approach using phenotypic (morphology and extrolite profiles) and molecular (sequences of its, beta-tubulin and calmodulin genes) characters. ascospores of e. stella-maris and e. olivicola have star-shape equatorial crests, those of e. filifera form long appendages that emerge radially from narrow stellate crests and ... | 2008 | 18959164 |
| angle alignment evokes perceived depth and illusory surfaces. | there is a distinct visual process that triggers the perception of illusory surfaces and contours along the intersections of aligned, zigzag line patterns. such illusory contours and surfaces are qualitatively different from illusory contours of the kanizsa type. the illusory contours and surfaces in this case are not the product of occlusion and do not imply occlusion of one surface by another. rather, the aligned angles in the patterns are combined by the visual system into the perception of a ... | 2008 | 19065852 |
| primordial germ cell specification from embryonic stem cells. | primordial germ cell (pgc) specification is the first crucial step in germ line development. however, owing to significant challenges regarding the in vivo system, such as the complex cellular environment and potential problems with embryo manipulation, it is desirable to generate embryonic stem (es) cells that are capable of overcoming these aforementioned limitations in order to provide a potential in vitro model to recapitulate the developmental processes in vivo. | 2008 | 19107197 |