| [immunologic response of divers working in the conditions of increased microbial contamination of water under pressure up to 5.1 mpa]. | the complex investigation of immune and nonspecific reactivity of 30 aquanauts was carried out during five experimental saturation divings up to 350-500 m accompanied by an increase of microbic contamination in water of the hyperbaric chamber. peculiarities of humoral immune response and phagocyte functions were found to depend on the inflammatory disease of aquanauts. it is concluded that the situational transitory immune deficiency development under the influence of hyperbaric factors is possi ... | 1991 | 1778260 |
| cloning and nucleotide sequencing of the gene encoding the beta-lactamase from citrobacter diversus. | the gene coding for the class a beta-lactamase of citrobacter diversus has been cloned and sequenced. it contains the information for a 294-amino-acid precursor protein, including a 27-residue n-terminal signal peptide. the deduced sequence of the n-terminal portion of the mature protein is in excellent agreement with that determined by microsequencing of the protein and readily explains the pi differences observed between the naturally occurring forms i and ii of the enzyme. the sequence of the ... | 1991 | 1778425 |
| enterotoxigenic klebsiella pneumoniae in acute childhood diarrhoea. | k. pneumoniae strains recovered as pure or predominant isolate from stool specimens of 50 children below three years of age, presenting with acute watery diarrhoea, were studied for heat-labile enterotoxin production. twenty three (46%) of the 50 crude toxin concentrates showed positivity in rabbit ileal loops and skin permeability tests. antigenically 17 (34%) and 20 (40%) of the toxin extracts reacted with immuno-purified anti h-lt antibody in latex particle agglutination and immuno-dot blot a ... | 1991 | 1778616 |
| pharmacokinetic evidence of imipenem efficacy in the treatment of klebsiella pneumoniae nosocomial meningitis. | | 1991 | 1778864 |
| cefaclor in the treatment of infective exacerbations of chronic bronchitis in cigarette smokers. | there is a direct correlation between number of cigarettes smoked and the incidence of lower respiratory tract infection in humans. in studies with smokers suffering from exacerbations of chronic bronchitis, the most common bacterial pathogens found were haemophilus influenzae, streptococcus pneumoniae, staphylococcus aureus and branhamella catarrhalis. antibiotics should be effective against such possible pathogens. cefaclor has demonstrated in vitro activity against all these pathogens. we des ... | 1991 | 1779259 |
| bacteremia in patients with cirrhosis of the liver. | infections are frequent in patients with liver cirrhosis, as their defenses against infectious agents are altered. but bacteremia occurring in cirrhotic patients has seldom been reported in the literature. from 1981 to 1986, we collected 197 cases with 228 episodes of bacteremia for this retrospective study. the incidence of bacteremia in cirrhotic patients was 8.8%; no significant difference was noted between cirrhotic patients with variant etiologies of hbv(+), hbv(-) and alcohol. but the inci ... | 1991 | 1779712 |
| identification of a nifa-like regulatory gene of azospirillum brasilense sp7 expressed under conditions of nitrogen fixation and in the presence of air and ammonia. | a gene bank of azospirillum lipoferum br17 constructed in the vector lambda gem11 was screened with a bradyrhizobium japonicum nifa gene probe. a 7.3 kb ecori fragment carrying a nifa-like gene was thereby isolated and subsequently used to screen a gene bank of azospirillum brasilense sp7 constructed in puc18. two ecori fragments of 5.6 kb and 3.6 kb covering the nifa-homology region were found. mutants with nif- phenotype were obtained by site-directed tn5 mutagenesis of the 5.6 kb fragment and ... | 1991 | 1779763 |
| an amplifiable and deletable chloramphenicol-resistance determinant of streptomyces lividans 1326 encodes a putative transmembrane protein. | a genetically unstable chloramphenicol resistance gene from streptomyces lividans 1326 was cloned and characterized. this gene and adjacent dna regions can be lost spontaneously or amplify within variants. biochemical studies proved that chloramphenicol is not modified by an acetyltransferase or any other enzyme and that ribosomes of the resistant strain are sensitive to chloramphenicol. sequence data revealed that the resistance gene encodes a hydrophobic protein predicted to have 12 membrane-s ... | 1991 | 1779766 |
| [adult respiratory distress syndrome complicating acute pyelonephritis in pregnancy]. | on the fifth day of a course of antibiotic therapy for acute klebsiella pyelonephritis, a 21-year-old pregnant woman developed adult respiratory distress syndrome. she improved rapidly on fluid restriction and intravenous furosemide and did not require mechanical ventilation. 17 weeks later, after 40 weeks of pregnancy, she spontaneously delivered a healthy male infant weighing 3280 g. | 1991 | 1783309 |
| interpretive criteria of antimicrobial disk susceptibility tests with flomoxef. | 320 recently isolated pathogens, 20 strains from each of 16 species, were investigated using mueller-hinton agar and din as well as nccls standards. the geometric mean of the agar dilution mics of flomoxef were 0.44 mg/l for staphylococcus aureus, 0.05 mg/l (klebsiella oxytoca) to 12.6 mg/l (enterobacter spp.) for enterobacteriaceae, 33.1 mg/l for acinetobacter anitratus, 64 mg/l for enterococcus faecalis, and more than 256 mg/l for pseudomonas aeruginosa. for disk susceptibility testing of flom ... | 1991 | 1783442 |
| 1,3-propanediol production by escherichia coli expressing genes from the klebsiella pneumoniae dha regulon. | the dha regulon in klebsiella pneumoniae enables the organism to grow anaerobically on glycerol and produce 1,3-propanediol (1,3-pd). escherichia coli, which does not have a dha system, is unable to grow anaerobically on glycerol without an exogenous electron acceptor and does not produce 1,3-pd. a genomic library of k. pneumoniae atcc 25955 constructed in e. coli ag1 was enriched for the ability to grow anaerobically on glycerol and dihydroxyacetone and was screened for the production of 1,3-pd ... | 1991 | 1785929 |
| parapharyngeal abscesses. | fifty-five patients with deep neck infections treated consecutively over a period of six and a half years between january 1983 and july 1989 were reviewed. nine of these patients had abscesses localized to the pharapharyngeal space and form the basis of this study. the aetiology of the parapharyngeal abscess was odontogenic in two patients and remained unknown in the other seven. five patients had associated systemic disease; four were diabetics and one patient had non-hodgkin's lymphoma. high d ... | 1991 | 1787355 |
| [differences in the pathogen spectrum of the conjunctival sac before and after irrigation of the lacrimal apparatus]. | the microbial flora in the conjunctival sac of 30 patients was investigated. qualitative and quantitative differences before and after irrigation of the lacrimal system were found. in some cases a quantitative increase was registered. in 12 cases conjunctival samples before and after irrigation changed. negative results before and bacterial growth of coagulase-negative staphylococci after irrigation were found in 4 cases. in 3 cases unfavourable changes were seen. pseudomonas, klebsiella and bet ... | 1991 | 1787655 |
| cassette mutagenesis implicates a helix-turn-helix motif in promoter recognition by the novel rna polymerase sigma factor sigma 54. | cassette mutagenesis has been used to study the role of a helix-turn-helix (hth) motif in the novel rna polymerase sigma factor sigma 54 of klebsiella pneumoniae. of the four residues which are predicted to be solvent-exposed in the second helix, the first (glu-378) tolerated all substitutions, and some mutations of this residue increased expression from sigma 54-dependent promoters. certain substitutions in the third exposed residue (ser-382) produced a promoter-specific phenotype and all subst ... | 1991 | 1787787 |
| ampicillin/sulbactam in lower respiratory tract infections: a review. | the pathophysiology and microbiology of lower respiratory tract infections are outlined and diagnostic and therapeutic problems considered. the use of sulbactam/ampicillin in the treatment of these infections is evaluated. the two drugs have similar pharmacokinetic characteristics; predictable and dose-dependent peak serum concentrations of both agents are achieved after parenteral administration. more than 90% of strains of staphylococcus aureus, haemophilus influenzae, moraxella catarrhalis, k ... | 1991 | 1790546 |
| [bacteriocinogeny in klebsiella and the applied use of klebocins]. | a phenomenon of bacteriocinogeny is studied in 83 k-type strains of klebsiella. physicochemical (permeability through cellophane, thermo-resistance, diffusion rate in agar, inactivation by trypsin, induction by uv irradiation) and biological (activity spectrum, specificity) properties are studied. eight preparations of klebocins are examined by electron microscopy. conclusions are made on the possibility to use klebocinogenic and indicating k-type cultures of klebsiella for bacteriocin typing of ... | 1991 | 1791782 |
| comparison of bacteraemic community-acquired lobar pneumonia due to streptococcus pneumoniae and klebsiella pneumoniae in an intensive care unit. | in a study of 41 consecutive patients with bacteraemia-associated community-acquired lobar pneumonia due to streptococcus pneumoniae and klebsiella pneumoniae an attempt was made to determine whether distinguishing criteria of disease due to these organisms could be identified according to demographic features and the results of initial clinical and laboratory investigations. such information would aid in the early initiation of appropriate antimicrobial therapy. the most significant difference ... | 1991 | 1792415 |
| [prolonged antibacterial action of polymer coated suture materials]. | the antimicrobial activity of capromed, a surgical polymer-coated sutural material containing dioxidine, quinoxidine or gentamicin was studied in vitro and in vivo. capromed was shown to be active against the hospital strains of s. aureus, e. coli, proteus spp., klebsiella spp. and p. aeruginosa. the antimicrobial activity of adh and ag threads was preserved for 3 to 4 days after implantation. the dh-2 and g-2 threads preserved their activity for 6 to 7 days. it was concluded that the duration o ... | 1991 | 1793296 |
| post-antibiotic effect of beta-lactam antibiotics on gram-negative bacteria in relation to morphology, initial killing and mic. | the in vitro post-antibiotic effect (pae) of cefepime, cefotaxime, ceftazidime and imipenem on reference strains of escherichia coli, enterobacter cloacae, klebsiella pneumoniae, pseudomonas aeruginosa and serratia marcescens were evaluated by bioluminescence assay of bacterial atp. in parallel with the pae determination, initial killing and morphology studies were performed. imipenem produced greater than 1 h pae on all strains tested, cefepime and cefotaxime on four strains and ceftazidime onl ... | 1991 | 1794362 |
| laser-desorption-ionization fourier-transform ion-cyclotron-resonance (ldi-ft-icr) mass spectrometry (m.s.) of bacterial oligosaccharides. | | 1991 | 1794584 |
| integration of catabolism and anabolism in microbial systems. | | 1991 | 1794594 |
| nosocomial infections in an intensive care unit. | a total of 676 patients were admitted to the intensive care unit, university hospital, kuala lumpur between january 1989 and march 1990. fifty-one hospital-acquired infections were recorded, giving a rate of 7.6%. the most frequent site of infection was the respiratory tract (41.2%), followed by the urinary tract (27.5%). most of the pathogens were gram-negative bacilli (71%). the three most common pathogens were klebsiella species, pseudomonas aeruginosa and staphylococcus aureus. | 1991 | 1795559 |
| structure of the o-specific polysaccharide chain from klebsiella pneumoniae o1k2 (nctc 5055) lipopolysaccharide. | the structure of the o-specific polysaccharide of klebsiella pneumoniae o1k2 lipopolysaccharide was investigated by use of methylation, periodate oxidation, partial hydrolysis, and 1h- and 13c-n.m.r. spectroscopy. it was shown to consist of a linear chain composed of two disaccharide repeating units, [----3)-alpha-d-galp-(1----3)-beta-d-galp-(1----] and [----3)-alpha-d-galp-(1----3)-beta-d-galf-(1----]. | 1991 | 1797395 |
| separation and characterization of three positional isomers of dimaltosyl-cyclomaltoheptaose (dimaltosyl-beta-cyclodextrin). | a mixture of maltosylcyclomaltoheptaoses (maltosyl-beta-cyclodextrins, g2-beta cds) was prepared from maltose and beta-cyclodextrin (beta cd) through the reverse action of klebsiella pneumoniae pullulanase. three positional isomers of dimaltosyl-beta cd in the mixture were separated by high-performance liquid chromatography on a reversed phase column and a graphitized carbon column. their molecular weights were measured by fast-atom bombardment mass spectrometry, and the structures were establis ... | 1991 | 1797438 |
| in vitro activity of a new cephalosporin me-1206 compared with other agents. | the in vitro activity of me-1206, a new aminothiazolyl cephalosporin that can be orally absorbed when converted to an ester, was compared with that of other beta-lactams. me-1206 inhibited 50% of the enterobacteriaceae at 2 micrograms/ml, similar to cefotaxime, ceftazidime, and cefixime. it did not inhibit, mic greater than or equal to 32 micrograms/ml, enterobacter species or citrobacter freundii resistant to cefotaxime and ceftazidime, and it was less active than cefotaxime and ceftazidime aga ... | 1991 | 1797456 |
| oral ofloxacin therapy of infections due to multiply-resistant bacteria. | we determined the efficacy and safety of orally administered ofloxacin, 400 mg twice daily, in the treatment of infections due to multiply-resistant bacteria. patients (n = 99) were treated for 84 infections in 82 patients evaluable for efficacy with a bacteriologic response of 71%. organisms treated included pseudomonas aeruginosa (39), staphylococcus aureus (11), serratia marcescens (9), enterobacter species (7), five each of escherichia coli, citrobacter, salmonella, klebsiella, and other org ... | 1991 | 1797458 |
| otitis media in sudanese children: presentation and bacteriology. | two hundred sudanese children (105 males, 95 females) with otitis media (om) were studied. their age range was from 3 months to 15 years, with 41.5% being below 2 years of age. the presenting symptoms included ear discharge in 96% and pyrexia in 26.5% of patients. ear ache and itching were reported in 22.5% and 7.0% respectively and impaired hearing in 7.0%. bacterial pathogens were isolated from 115 (70.1%) of 164 cultures from children with chronic discharging ears. organisms isolated in order ... | 1991 | 1797530 |
| clinical & bacteriological profile of neonatal pneumonia. | in a prospective study of 44 neonates (33 outborn and 11 inborn) with pneumonia, the bacteriology of pneumonia was determined by blood culture and serum counterimmunoelectrophoresis (ciep). twenty-nine babies also underwent lung aspiration. the lung aspirate was subjected to bacterial culture and ciep. ciep was done to detect the bacterial antigens of streptococcus pneumoniae and haemophilus influenzae. absence of tachypnoea, found more commonly in low birth weight babies, was a poor prognostic ... | 1991 | 1797646 |
| [susceptibilities of clinical bacterial isolates to antimicrobial agents, 1989. a study mainly focused on imipenem. the research group for testing imipenem susceptibilities of clinical isolates]. | we investigated susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antimicrobial agents at hospital laboratories throughout japan from september to december of 1989. the susceptibility testing was carried out according to the 1-dilution or 3-dilution disc technique in which susceptibilities are classified into 4 grades: (+++), (++), (+) and (-). ipm showed markedly high in vitro activities against streptococcus pneumoniae, neisseria gonorrhoeae, moraxella catarrhalis, es ... | 1991 | 1798067 |
| [desiccated rattlesnake capsules: a potential source of gram-negative bacterial infection]. | the ingestion of rattlesnake powder capsules is frequent in mexico in view of their alleged curative properties in various diseases, among them different malignancies. based on previous reports showing both bacteremia and septicemia in patients with malignant diseases ingesting such capsules, we conducted a study to evaluate the presence of microorganisms in 16 different preparations of rattlesnake powder capsules, obtained in six different cities of our country. we found that all the samples we ... | 1991 | 1798864 |
| [in vitro comparison of ciprofloxacin with other antibiotics against multiresistant gram-negative bacilli]. | in 2784 specimens submitted to the clinical microbiology laboratory of the instituto nacional de neurología from may 1989 to january 1990, 140 (5.0%) had gram negative bacilli (gnb) resistant to five or more antibiotics. one hundred different isolates recovered from urine, tracheal aspirates, blood, cerebrospinal fluid, surgical wound infections and other sites were studied. pseudomonas spp, enterobacter spp, klebsiella pneumoniae and escherichia coli accounted for 86% of the total. disk diffusi ... | 1991 | 1798865 |
| analysis of k. pneumoniae by monoclonal antibody: immunohistochemical detection of k. pneumoniae surface antigen injected into mice and rats. | the monoclonal antibody kp62 recognized surface antigenic determinants of some strains of klebsiella pneumoniae. the antigen recognized by kp62 was demonstrated on the bacterial surface using immunoelectron microscopy. kp62 reacted with k. pneumoniae no. 1 or k. pneumoniae b 5055 and lipopolysaccharide (lps) from the same bacteria. however, kp62 was not inhibited by the lps from escherichia coli (e. coli) o111:b4 and e. coli o55:b5. thus, kp62 might be a useful monoclonal antibody to detect k. p ... | 1991 | 1800312 |
| neonatal septicaemia among inborn and outborn babies in a referral hospital. | neonatal sepsis was studied among one hundred neonates (50 hospital born and 50 outborn babies) over one year period. the incidence of neonatal septicaemia was 15.5 per 1000 live births in the hospital. among outborn babies it accounted for 6.1% of total pediatric admissions and 43.7% of sick neonates referred from outside. low birth weight and prematurity were important predisposing factors in both the groups. blood culture was positive among 32% of outborn and 34% of inborn babies. coagulase-n ... | 1991 | 1800336 |
| cefpodoxime: comparative antibacterial activity, influence of growth conditions, and bactericidal activity. | the antimicrobial activity of cefpodoxime, the active metabolite of the new cephalosporin ester cefpodoxime proxetil, in comparison to cefixime, cefotiam, cefuroxime, and cefotaxime was determined against a broad spectrum of freshly isolated gram-positive and gram-negative bacterial strains. cefpodoxime was demonstrated to be inhibitory at concentrations of less than or equal to 1 mg/l against 90% of strains of moraxella catarrhalis, haemophilus influenzae, escherichia coli (beta-lactamase- nega ... | 1991 | 1800379 |
| asymptomatic bacteriuria in school children in a rural area, egypt. | forty hundred and fifty urine samples collected from school children in a rural area were screened for the presence of significant bacteriuria. the incidence of asymptomatic bacteriuria was found to be 7% with predominance in females (11%) than in males (3.6%). from the total bacterial isolates e. coli were isolated in 18% of cases, co-agulase positive staphylococci in 30%, co-agulase negative staphylococci in 15%, streptococcus pyogenes in 6%, klebsiella species in 9% and enterococci in 21% of ... | 1991 | 1800613 |
| [neonatal bacterial infections in the tropical zone]. | one thousand and ten miscellaneous samples collected from infected newborns, were tested at the bacteriology laboratory of a. royer children's hospital from 1983 to 1991. these samples included 471 blood cultures, 114 pus of various origins, 410 cerebrospinal fluids and 15 urines. one bacteria or bacterial soluble antigens were detected in 294 samples (29.2%). positivity percentage was 29.2% for septicemia, 68.4% for suppurations, 17.8% for meningitidis and 33.3% for urinary tract infections. al ... | 1991 | 1800882 |
| comparative trial of norfloxacin and macrocrystalline nitrofurantoin (macrodantin) in the prophylaxis of recurrent urinary tract infection in women. | eighty-eight women with a history of recurrent urinary tract infection (at least four attacks in the preceding 12 months) were randomized to take either norfloxacin 200 mg at night (45 patients) or macrocrystalline nitrofurantoin 100 mg at night (43 patients) for 12 months. a decrease in the number of symptomatic attacks while taking this prophylaxis was observed in 94 per cent of the patients and this improvement was maintained during the 6 months following the end of prophylaxis in 69 per cent ... | 1991 | 1801054 |
| [scapulohumeral arthritis caused by klebsiella pneumoniae]. | | 1991 | 1801080 |
| [microbial colonization and succession on the faucial mucosa in newborn infants rooming in with their mothers in a maternity hospital]. | the formation of microflora on the laryngeal mucosa in newborn infants during the first 5 days of their life was studied in one of the maternity hospitals of moscow. in this work modern methods of the isolation and identification of aerobic and anaerobic microorganisms were used, and the results thus obtained were computer-processed. in the maternity hospital of the "mother-child" type the microbial colonization of the laryngeal mucosa by normal and opportunistic microorganisms was noted in newb ... | 1991 | 1801480 |
| [the characteristics of the contact of proteolytic strains of proteus mirabilis and klebsiella pneumoniae with enterocytes in vivo]. | the relationships of opportunistic p. mirabilis and k. pneumoniae, both having proteolytic properties, with enteric cells in white mice have been studied on a ligated intestinal loop, used as an experimental model, by electron microscopy. this investigation has shown that the strains under study are capable of damaging the membrane of the jagged edge of enteric cells at the distance of the spread of proteolytic metabolites. this damage is reversible, presenting as compensatory protective reactio ... | 1991 | 1801481 |
| [the effect of immunotherapy with cell-free vaccines made from the antigens of opportunistic microorganisms on the dynamics of dna antibody formation]. | the sera of patients subjected to immunotherapy with staphylococcal vaccine and with multicomponent vaccine (i.e. the mixture of the antigenic preparations of staphylococcus aureus, klebsiella pneumoniae, proteus vulgaris, escherichia coli) were studied by the method of the enzyme immunoassay on the basis of cattle spleen dna. immunotherapy with staphylococcal vaccine was given to patients with dermal diseases, chronic obstructive bronchitis and pulmonary abscess. multicomponent vaccine was intr ... | 1991 | 1801489 |
| [trials to improve the media used for the methyl red reaction (mrt). ii]. | the evolution of the methyl rot reaction (mrt), expressed by the ph dynamics in the first 18 hours was examined. a medium made of caseine or soya hydrolysate distributed in small volumes, was experimented versus a control broth made of meat peptone (clark-lubs). for klebsiella the results showed that in the control group the ph acidifies and remains low, thus mimicking a positive reaction. in the caseine/soya medium, a decrease of ph at 4-8 hours is first noticed. initial acidification, consecut ... | 1991 | 1802291 |
| acute anterior uveitis, arthritides and enteric antigens. | one hundred and fourteen patients with acute anterior uveitis were studied for the presence of the hla-b27 tissue type, the prevalence of spondylitis and arthritis and the occurrence of gastro-intestinal and urogenital infections or diarrhoeal illness in the history. eighty-seven (76%) were b27+ and 27 (24%) b27-. forty-two (48%) of the b27+ group had ankylosing spondylitis (as); 13 (30%) of them were females. sacroilitis (si) with no spinal involvement was present in 21 patients (24%), 13 (61%) ... | 1991 | 1802494 |
| purification of equine neutrophil lysozyme and its antibacterial activity against gram-positive and gram-negative bacteria. | lysozyme from equine neutrophil granulocytes was isolated in a pure form by fast performance liquid chromatography, i.e. ion-exchange chromatography and reversed-phase chromatography. the lysozyme lysed micrococcus luteus, bacillus subtilis and staphylococcus lentus and was also bactericidal against the gram-negative bacteria escherichia coli, klebsiella pneumoniae, bordetella bronchiseptica, and serratia marcescens. staphylococcus aureus and staphylococcus epidermidis were not lysed. the lysozy ... | 1991 | 1803722 |
| in vitro studies with five quinolones: evidence for changes in relative potency as quinolone resistance rises. | a panel of 203 staphylococci, enterobacteriaceae, pseudomonas aeruginosa, and miscellaneous nonfermentative gram-negative bacilli were chosen for their various susceptibilities to ciprofloxacin. on the basis of agar dilution susceptibilities, each of the four taxonomic groups was divided into ciprofloxacin-susceptible, moderately resistant, and highly resistant subgroups, and each subgroup was then further analyzed for its susceptibility to the fluoroquinolones ci-960, ci-990, sparfloxacin, and ... | 1991 | 1804005 |
| crossover assessment of serum bactericidal activity and pharmacokinetics of ciprofloxacin alone and in combination in healthy elderly volunteers. | to better define the pharmacokinetics and serum bactericidal activity (sba) of ciprofloxacin and other antimicrobial agents in the elderly, six healthy (greater than 65 years) volunteers with normal renal function were given ciprofloxacin alone orally, ciprofloxacin plus rifampin orally, ciprofloxacin plus clindamycin orally, rifampin alone orally (three volunteers), and, for comparison of sba against gram-positive cocci, vancomycin intravenously. mean peak ciprofloxacin concentrations and other ... | 1991 | 1804008 |
| activity of meropenem against antibiotic-resistant or infrequently encountered gram-negative bacilli. | meropenem was compared in vitro with imipenem as well as with several other contemporary beta-lactams, ciprofloxacin, and gentamicin against a group of highly antibiotic resistant members of the family enterobacteriaceae and a collection of oxidase-positive and/or glucose-nonfermentative gram-negative bacilli. in this study, meropenem was more active than imipenem against isolates of enterobacter, klebsiella, morganella, providencia, alcaligenes, aeromonas, and pasteurella. | 1991 | 1804016 |
| in vitro and in vivo activity of carbamate-linked dual-action antibacterial ro 24-4383. | ro 24-4383 contains desacetylcefotaxime linked by a carbamate bond at the 3' position to ciprofloxacin. ro 24-4383 was active against 99% of the 363 gram-positive and gram-negative aerobes tested in vitro, while the comparative agents cefotaxime and ciprofloxacin were active against 77 and 97%, respectively. the activities (ed50: mg/kg s.c.) of ro 24-4383, cefotaxime and ciprofloxacin in systemic murine infections were: escherichia coli 257, 1.4, less than 0.5, less than 0.2; klebsiella pneumoni ... | 1991 | 1804592 |
| [bactericidal effect of cefadroxil, amoxicillin alone or in combination with clavulanic acid in sera of healthy volunteers]. | determination of minimal inhibitory concentrations (mics) provides data on the susceptibility or resistance of a bacteria; however, in susceptible bacteria this parameter is not predictive of effectiveness of the antimicrobial agent. bactericidal activities of cefadroxil, of amoxicillin, and of the amoxicillin-clavulanic acid combination on bacteria commonly found in ent and lower respiratory tract disease were studied comparatively. the antibiotics were given by the oral route to six healthy vo ... | 1991 | 1805138 |
| what is the diagnostic value of beta-d-glucuronidase (bdg) activity of bacteria using fluorocult ecd agar for their cultivation? | a total of 1510 strains from 15 genera of gram-negative and gram-positive bacteria were studied. more than 94% of 327 escherichia coli strains showed beta-d-glucuronidase (bdg) activity. seventeen serotypes from 170 e. coli o serogroup representatives were negative. relationship between the existence of bdg positive and negative e. coli strains in the same serogroup or serotype has not been observed. the rate of bdg positivity was 42% among salmonella arizonae strains and 42.2% among shigella st ... | 1991 | 1805501 |
| frontofacial advancement with a free flap: deadspace versus drainage. | presented is an adult case of crouzon's syndrome undergoing a single stage frontofacial advancement where the employment of a microvascular free flap for extradural deadspace obliteration and to seal any communication with the nose may have contributed to the development of a major extradural infection. | 1991 | 1807413 |
| mortality in neonatal septicemia with involvement of mother in management. | in most special care neonatal units (scnus) in india, mothers are excluded from the care of their sick babies for fear of over-crowding and dislocation. we have attempted to study the feasibility of involving mothers in the care of their babies admitted for neonatal septicemia and to analyse whether this changed the sepsis related case fatality rate. the study material consisted of 158 neonates with blood culture positive neonatal septicemia whose mothers were actively involved in their care dur ... | 1991 | 1808045 |
| neonatal septicemia: a reappraisal with special reference to the use of cefotaxime. | in a study period of one year, 381 babies (38.7% of all nursery admissions) were clinically diagnosed to have sepsis. of these, 156 (40.9%) had positive blood cultures. klebsiella was by far the commonest organism isolated (41%) followed by other gram negative organisms. gram positive organisms were uncommon (8%). sensitivity of gram negative organisms was poor to penicillin (11%) and ampicillin (18%); significantly better to kanamycin (65%), gentamicin (74%) and best to cefotaxime (79%). only 8 ... | 1991 | 1808046 |
| clinical results of a multicenter study with sulbactam/ampicillin for the treatment of patients with lower respiratory and urinary tract infections. | a total of 124 patients with lower respiratory tract (44) or urinary tract infections (80) were enrolled in an open, multicenter study to evaluate the efficacy and tolerability of sulbactam/ampicillin, administered at the dosage of 3 g/die by intramuscular route. pretreatment pathogens from patients with lower respiratory tract infections included: streptococcus alpha-haemolyticus in 8 cases, streptococcus beta-haemolyticus in 2 cases, staphylococcus albus in 7 cases, haemophilus influenzae in 7 ... | 1991 | 1809811 |
| molecular analysis of two fructokinases involved in sucrose metabolism of enteric bacteria. | sucrose-positive derivatives of escherichia coli k-12, containing the plasmid pur400, and of klebsiella pneumoniae hydrolyse intracellular sucrose 6-phosphate by means of an invertase into d-glucose 6-phosphate and free d-fructose. the latter is phosphorylated by an atp-dependent fructokinase (gene scrk of an scr regulon) to d-fructose 6-phosphate. the lack of scrk does not cause any visible phenotype in wild-type strains of both organisms. using genes and enzymes normally involved in d-arabinit ... | 1991 | 1809835 |
| septic endophthalmitis associated with bacteremia and liver abscess caused by klebsiella pneumoniae. | pyogenic liver abscess is a serious clinical problem associated with severe complications in 10-20% of cases. metastatic septic endophthalmitis is a rare complication associated with liver abscess. despite appropriate treatment the outcome is devastating. we will review in this case presentation some important aspects of the etiology, diagnosis and treatment recommendations for septic endophthalmitis. | 1991 | 1811594 |
| analysis of pyruvic acid acetal containing polysaccharides by methanolysis and reductive cleavage methods. | the mass spectra of permethylated methyl 4,6-o-(1-carbomethoxyethylidene)-d-hexopyranoside and 1,5-anhydro-d-hexitol of glucose, galactose, and mannose and permethylated methyl 5,6-o-(1-carbomethoxyethylidene)-d-galactofuranoside and 1,4-anhydro-d-galactitol have been determined. the stability of each compound toward methanolysis and reductive cleavage is discussed. these techniques permit the identification of the acetalic linkages of pyruvic acid present in polysaccharides. | 1991 | 1812780 |
| epidemiological study of klebsiella pneumoniae isolated from neonatal patients and environment. | | 1991 | 1813420 |
| [microbial colonization and succession in the large intestine of newborn infants during their stay with mothers at the maternity hospital]. | formation of microflora in the large intestine of 5-day old infants was studied in one of the moscow maternity homes. the up-to-date procedures for isolation and identification of aerobic and anaerobic organisms were used in the study and the findings were processed on a computer. in the newborns of the maternity home of the "mother-infant" type there was observed colonization of the large intestine with aerobic and anaerobic organisms. a wave-like dynamics in the formation of the symbiotic micr ... | 1991 | 1814270 |
| bacteriology of community acquired urinary tract infection. analysis of 1048 cases. | urine samples from 1048 cases clinically suspected to have urinary tract infection were examined for bacteriological culture and antibiotic sensitivity. of 1048 cultures, 530 (50.5%) were sterile, 163 (15.5%) showed the presence of nonpathogenic bacteria and 11 (1%) revealed nonsignificant bacteriuria with escherichia coli. significant bacteriuria (more than 10(5)/ml) was found in the remaining 344 (32.8%) cases. escherichia coli was the predominant pathogen isolated from 170 (16.2%) samples; kl ... | 1991 | 1814873 |
| epidemiological fingerprinting of klebsiella pneumoniae by small-fragment-restriction-endonuclease-analysis (sf-rea). | epidemiological fingerprinting of klebsiella pneumoniae was performed by restriction endonuclease analysis (rea) of whole cell dna. 11 isolates from 4 patients in an intensive care unit and 80 unrelated strains were examined in this study. dna was cleaved with restriction endonuclease ecor i, electrophoresed on 10% polyacrylamide gels, and restriction fragment patterns were visualized by silver staining. the analysis of small fragments within the cleavage patterns (sf-rea) yielded sufficient inf ... | 1991 | 1815337 |
| reduction of capsular polysaccharide and potentiation of aminoglycoside inhibition in gram-negative bacteria by bismuth subsalicylate. | bismuth subsalicylate (bss), sodium salicylate, and bismuth nitrate were compared with respect to their effects on capsular polysaccharide (cps) production, bacterial growth inhibition, and potentiation of aminoglycoside inhibition on strains of gram-negative bacteria. at 250 microm, bss reduced cps production in klebsiella pneumoniae cultures by greater than 90% in contrast to a 36% reduction by salicylate. at 500 microm, salicylate reduced cps by 52%, versus a 70% reduction by bismuth nitrate. ... | 1991 | 1816178 |
| the effects of sub-mics of cefonicid on the interaction of human macrophages with klebsiella pneumoniae. | | 1991 | 1816190 |
| technetium-99m distribution into klebsiella pneumoniae. | bacteria labelled with radionuclide has been the subject of much investigation and has been applied in microbiological research. technetium-99m (99mtc) may be an alternative radionuclide for the labelling of bacteria employed in various microbiological procedures. this radionuclide is easily available, is not expensive and presents important physical and biological characteristics. 99mtc-labelled bacteria are stable and their cell viability and biological properties are not modified. study of th ... | 1991 | 1816872 |
| formation of nitrogen-containing metabolites from geniposide and gardenoside by human intestinal bacteria. | during the course of our studies on the metabolism of iridoid glycosides by human intestinal bacteria, we found that geniposide (1) and gardenoside (4) were transformed to new nitrogen-containing compounds, genipinine (3) and gardenine (6), respectively, along with the known aglycones. although the amounts of new metabolites were somewhat lower than those of the aglycones, they were quantitatively analyzed by means of liquid chromatography/mass spectrometry (lc/ms). of 25 strains of human intest ... | 1991 | 1818345 |
| association of klebsiella organisms with pulmonary lesions in sheep. | small nodules were seen on chest wall and in the lungs of sheep slaughtered in al-ahsa abattoir, saudi arabia. klebsiella pneumoniae subspecies ozaenae was isolated and characterized. the histopathology of the nodules was described. | 1991 | 1818362 |
| in vivo effects of ru41740 in aged humans: evaluation of some immunological parameters. | the immunological effects of the oral administration of ru41740 in hypo-anergic aged humans are reported. significant restoration of cellular immunity, evaluated by skin tests, and increase of percentage of cd3+, cd2+, cd4+ and hnki+ lymphocytes and phagocytic activity are demonstrated. | 1991 | 1818516 |
| antibacterial activities of amoxicillin alone and in combination with clavulanic acid correlated with beta-lactamase production. | amoxicillin, a beta-lactam antibiotic, was tested for its effect in combination with clavulanic acid, a beta-lactamase inhibitor, against 9 species of bacteria isolated from clinical specimens. a total of 698 strains of bacteria were tested for beta-lactamase production by the rapid chromogenic cephalosporin method. their susceptibilities to amoxicillin alone and in combination with clavulanic acid were tested by the agar dilution method. the percentage of beta-lactamase producing strains ranged ... | 1991 | 1818798 |
| [neonatal septicemia and meningitis caused by gram-negative bacilli in yaondé: clinical, bacteriological and prognostic aspects]. | based on 139 cases collected in 36 months, the authors show that neonatal sepsis and meningitis with gram negative bacilli represent 62.33% of confirmed neonatal sepsis (223 cases out of 6,784 neonatal hospitalisations). 53.96% of cases are manifest within the first 72 hours of life. 35.25% of these infants are preemies. the principal predisposing factors are: foul-smelling leukorrhea (45.23%), prolonged rupture of membranes (26.62%) and notion of resuscitation (36.69%). the most important clini ... | 1991 | 1819407 |
| [virological and bacteriological study of materno-fetal infections in brazzaville]. | serological study of serum samples taken from pregnant women and umbilical cord and bacteriological study of vaginal secretions samples and cerebrospinal fluid (csf) showed in mothers: t. pallidum antibody (tp ab) 9%, rubella virus antibody (ru ab) 85%; hbs ag 16%, hiv antibody (hiv ab) 4%. microbe culture showed: s. aureus 18%, streptococcus sp. 9%, e. coli 4.9%, klebsiella 3.6%, citrobacter 3.6%, candida albicans 15%; direct immunofluorescence: chlamydia 26%. in infants: igg umbilical cord: tp ... | 1991 | 1819414 |
| a comparative study on aztreonam, ceftazidime and amikacin in the treatment of complicated urinary tract infections. | in a prospective, randomized trial, aztreonam (1 g intravenously or intramuscularly, twice daily) was compared with ceftazidime (1 g intravenously or intramuscularly, twice daily) and amikacin (500 mg intravenously or intramuscularly, twice daily) in 76 patients aged 24 to 84 years (mean, 59.7 years) with complicated urinary tract infections. initial pathogens included escherichia coli (47.5%), pseudomonas aeruginosa (22.5%), klebsiella spp. (9%), proteus spp. (7.5%) and enterobacter spp (6%). i ... | 1991 | 1819621 |
| [the bacteriocin typing of klebsiella pneumoniae strains]. | results of bacteriocin typing of 196 strains of the klebsiella genus are presented. they are typified by their sensitivity to bacteriocins and by their production using colicinogenic and indicating strains from collection of p. fredericq [correction of frederick], d. g. kudlaĭ, n. i. koshanova as well as klebocinogenic k-type cultures of klebsiella previously suggested by the authors. investigation results have shown sufficient stability of a bacteriocinotype of the cultures confirmed by the pop ... | 1991 | 1819760 |
| informative value of a mouse model of klebsiella pneumoniae infection used as a host-resistance assay. | to obtain a host-resistance assay (hra) for quantitative evaluation of immunostimulatory effects of various substances, an experimental model of k. pneumoniae inhalatory infection was elaborated. the highly virulent bacterial strain (inhalation ld50 = 400 cfu), applied via the natural route into the respiratory tract elicits an acute infectious process possessing characteristic dynamics. although the intensity of clearance in the bronchoalveolar lavage after challenge or the mean survival time c ... | 1991 | 1823654 |
| successful treatment of infected thoracoabdominal aortic graft by percutaneous catheter drainage. | a large perigraft abscess infected with klebsiella sp. developed around a woven dacron prosthesis inserted into a patient at high-risk with a leaking thoracoabdominal aortic aneurysm. percutaneous insertion of a sump drainage catheter under ultrasound guidance accompanied by local and systemic antibiotic therapy was the only reasonable management option. two years later the patient remains well with no evidence of sepsis on clinical examination, hematologic studies, computerized tomography or in ... | 1991 | 1826333 |
| [kpn378 i class 2 restriction endonuclease from klebsiella pneumoniae]. | | 1991 | 1827657 |
| on the role of histidine residues in cyclodextrin glycosyltransferase: chemical modification with diethyl pyrocarbonate. | ethoxyformylation with diethyl pyrocarbonate of approximately 1.5 his residues per molecule of enzyme reduced the cyclising activity of both the alpha-cyclodextrin glycosyltransferase from klebsiella pneumoniae strain m 5 al and the beta-cyclodextrin glycosyltransferase from bacillus circulans strain 8 by greater than 90%. pre-incubation with substrate protected the enzymes from ethoxyformylation. digestion of starch by the modified enzymes resulted in a delayed formation of cyclodextrins (cyclo ... | 1991 | 1828005 |
| [pharmacokinetic and clinical studies of cefpirome in pediatric field]. | we conducted a study on the pharmacokinetics and clinical application of cefpirome (cpr) in children. 1. a single intravenous injection of 20 mg/kg of cpr was given to a two-month-old boy, and the concentration of the drug in the blood was measured. fifteen minutes after administration, the concentration was 53.3 micrograms/ml, and it gradually decreased thereafter, reaching a level of 5.18 micrograms/ml after 8 hours with a half-life in the plasma of 2.36 hours. 2. a single intravenous injectio ... | 1991 | 1828275 |
| [bacteriological aspects of acute cholangitis with gallstones]. | the bacteria found in the bile and blood of 45 patients (27 men, 18 women; mean age 69 years) suffering from acute cholangitis with gallstones were studied in order to determine the appropriate antibiotic therapy. before any antibiotic was prescribed, a series of haemocultures was performed under aerobic and anaerobic conditions, and later gallbladder bile samples were taken during the operation. blood cultures were positive in 55 percent of the cases and bile cultures in 84 percent. the bacteri ... | 1991 | 1828581 |
| [gram-negative vascular puncture infections in patients with hemodialysis]. | | 1991 | 1829818 |
| increased expression of c3b and c3bi receptors on human neutrophils and monocytes induced by a glycoprotein extract from klebsiella pneumoniae (ru41740). | ru41740 is a glycoprotein extract from klebsiella pneumoniae with immunomodulating properties under different experimental conditions. in particular the compound is able to stimulate several functions of human phagocytes in vitro and ex vivo. using monoclonal antibodies and flow cytometry, in this work we assessed the effect of ru41740 on surface expression of receptors for c3b (cr1) and c3bi (cr3) in human phagocytic cells in vitro. the incubation of whole blood with varying ru41740 concentrati ... | 1991 | 1830041 |
| pharmacodynamics of amikacin in vitro and in mouse thigh and lung infections. | a variety of in-vitro and animal studies were performed to define the pharmacodynamic characteristics of amikacin against gram-negative bacilli and to determine the impact of the dosing regimen on therapeutic efficacy. mice with impaired renal function were included in these studies to more closely simulate in animals the pharmacokinetics of amikacin observed in humans. amikacin exhibited concentration-dependent killing and produced prolonged postantibiotic effects both in vitro and in vivo. in ... | 1991 | 1830302 |
| [resistance of hospital flora to imipenem. experience in two intensive care units]. | imipenem is a beta-lactam antibiotic active against most gram-negative bacilli. between july 1, 1987 and september 30, 1989 (9 semesters), the activity of imipenem against 6 micro-organisms was tested in two intensive care units attached to the university hospital of caen (normandy). during the same period, the consumption of imipenem was evaluated from the number of vials drawn by each of these two units from the central pharmacy. imipenem was found to be 100 percent effective against 5 of the ... | 1991 | 1835072 |
| [the spread of klebsiella in obstetrical hospitals and the biological properties of the isolated strains]. | examination of 278 newborn infants, parturients, and medical personnel in two maternity hospitals revealed a high level of klebsiella colonization of all examined biotopes of infants (the nasal cavity in up to 36.5% of cases) and the skin of the mammary glands of nursing mothers (in 36.2% of cases). in the intestine and the nasal cavity of parturient women and medical personnel klebsiella could be detected 3-10 times more often than in the same biotopes of nonhospitalized pregnant women. from 25 ... | 1991 | 1835234 |
| [the role of antibiotics in the prevention of cross infections in newborn infants and mothers during the puerperium]. | epidemiological efficiency of antibiotic prophylaxis of hospital infections (his) in maternity homes was analyzed by the materials on the clinical observation of 43995 newborns and their mothers within a period of 1986 to 1989 as well as by the data on the bacteriological examination of 6616 smears from the mucosa of the nose, pharynx, rectum and umbilical wounds of 1890 newborns carried out within the same period. it was shown that the prophylactic use of the antibiotics in the maternity homes ... | 1991 | 1835348 |
| [the detection of pathogenic properties in soil nitrogen-fixing enterobacteria]. | two klebsiella planticola nitrogen-binding soil strains have been found capable, when introduced intraperitoneally into white mice, of killing the animals, the ld50 of the strains being 8.8 +/- 0.1 and 9.0 +/- 0.2. in two k. pneumoniae strains isolated from internal organs of sick agricultural animals the presence of nitrogen-binding activity has been established. | 1991 | 1838655 |
| impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. | an experimental klebsiella pneumoniae pneumonia and septicemia in leukopenic rats was used to study the impact of the duration of infection on the bactericidal activity of ceftazidime, gentamicin and ciprofloxacin. it appeared that the number of bacteria persisting after a single intravenous injection progressively increased with delay of antibiotic administration up to 3 h after bacterial inoculation with each of the drugs tested. this effect was most pronounced for ciprofloxacin. an inoculum e ... | 1991 | 1839380 |
| branched saccharides formed by the action of his-modified cyclodextrin glycosyltransferase from klebsiella pneumoniae m 5 al on starch. | digestion of potato starch with his-modified alpha-cyclodextrin glycosyltransferase from klebsiella pneumoniae m 5 al yielded branched tetra- to nona-saccharides, as revealed by debranching with pullulanase. maltose and maltotriose stubs preponderated together with small proportions of d-glucose stubs. the branched saccharides accounted for approximately 1.2% of the starch. | 1991 | 1839890 |
| a neonate with bilateral refractory chylothorax--a case report. | a thirty six week gestation male baby weighing three kilogram was born to a twenty five year old mother by spontaneous vaginal delivery. at four hours of life, the baby developed respiratory distress with cyanosis and was admitted to the neonatal intensive care unit. there was clinical and radiological evidence of bilateral pleural effusion. thoracentesis revealed a transudate. repeated thoracentesis was necessary to relieve the respiratory distress. subsequently, multi resistant klebsiella aero ... | 1991 | 1840449 |
| cloning and analysis of the beta-galactosidase-encoding gene from clostridium thermosulfurogenes em1. | clostridium thermosulfurogenes em1 produced a thermostable (up to 70 degrees c) beta-galactosidase (beta gal) with a ph optimum of 7 during growth on lactose. the gene (lacz) encoding this enzyme was cloned and expressed in escherichia coli using puc18 as a vector. the nucleotide sequence of a 2.7-kb psti fragment carrying the lacz gene was determined. the open reading frame for lacz, which encoded a protein of 716 amino acids with a calculated mr of 83,728, was confirmed by the identity of its ... | 1991 | 1840542 |
| sequence and structural organization of a nif a-like gene and part of a nifb-like gene of herbaspirillum seropedicae strain z78. | the deduced amino acid sequence derived from the sequence of a fragment of dna from the free-living diazotroph herbaspirillum seropedicae was aligned to the homologous protein sequences encoded by the nifa genes from azorhizobium caulinodans, rhizobium leguminosarum, rhizobium meliloti and klebsiella pneumoniae. high similarity was found in the central domain and in the c-terminal region. the h. seropedicae putative nifa sequence was also found to contain an interdomain linker similar to that co ... | 1991 | 1840608 |
| comparative in vitro activity of cefixime, cefaclor and loracarbef against urinary pathogens. | minimum inhibitory concentrations of cefixime, cefaclor and loracarbef have been determined against 200 strains of bacteria, representing a wide selection of species causing urinary infections. cefixime was poorly active against gram-positive species, but was active (mic90 less than 2 mg/l) against almost all the gram-negative pathogens tested (except pseudomonas aeruginosa), and particularly so against klebsiella pneumoniae and members of the tribe proteae. cefaclor and loracarbef were more act ... | 1991 | 1841042 |
| [neonatal bacterial infections: a retrospective study over 8 years]. | in a retrospective study, one thousand and ten miscellaneous samples coming from infected newborns and tested at the bacteriology laboratory of a. royer children's hospital from 1983 to 1991 were reviewed. these samples included 471 blood cultures, 114 pus of various origins, 410 cerebrospinal fluids and 15 urines. one bacterium or bacterial soluble antigens was detected in 294 samples (29.2%). positivity percentage was 29.2% for septicemias, 68% for suppurations, 17.8% for meningitidis and 33.3 ... | 1991 | 1842774 |
| experimental otitis media with effusion induced by lipopolysaccharide from klebsiella pneumoniae. mucociliary pathology of the eustachian tube. | otitis media with effusion (ome) is generally benign and self-limiting but is often recurrent and can change into a chronic type. we have previously reported that intratympanic inoculation of lipopolysaccharide (lps) from klebsiella pneumoniae can develop experimental ome in the guinea pig. however, ome induced by 10 micrograms/ml of lps was of a self-limiting type. our hypothesis was that a higher concentration of lps might develop a chronic ome because lps reduces the ciliary activity in the t ... | 1991 | 1842860 |
| [spontaneous bacterial peritonitis: occurrence in chronic liver disease patients in recife]. | a prospective research was made on spontaneous bacterial peritonitis (sbp) in chronic liver disease patients presenting with ascites. forty clinical cases, of 37 patients, were analysed. all subjects were submitted to clinical and laboratory evaluation and diagnostic paracentesis, and the material was obtained for biochemical dosages, ph determination, cytology and bacterial cultures. thirty cases of sterile ascites and 10 of sbp (25%) were detected. in 5 (50%) with sbp, the clinical findings we ... | 1991 | 1843242 |
| [treatment of uncomplicated urinary tract infections: cefuroxime vs cotrimoxazole]. | forty females (ages 15-74) with community-acquired, uncomplicated urinary tract infections were studied. clinical and microbiological efficacy of cefuroxime (250 mg td) and trimethoprim sulfamethoxazole (160/800 mg td) used for 7 days were evaluated. the microorganisms found in the pre-treatment urinary cultures were: escherichia coli (85%), klebsiella pneumoniae (12.5%), and e. agglomerans (2.5%). they were all susceptible to cefuroxime, and 42.5% were resistant to trimethoprim sulfamethoxazole ... | 1991 | 1844773 |
| in vitro transcription of the histidine utilization (hutuh) operon from klebsiella aerogenes. | the promoter region preceding the hutuh operon in klebsiella aerogenes contains two oppositely oriented, overlapping promoters. in the absence of catabolite gene activator protein-cyclic amp (cap-camp), transcription proceeds primarily from the backward-oriented promoter (pc), whose function has not yet been determined, and only very weakly from the forward hutuh promoter, hutup. in the presence of cap-camp, pc is repressed and transcription from hutup is favored. two protein components required ... | 1991 | 1846133 |
| topoisomerase mutants and physiological conditions control supercoiling and z-dna formation in vivo. | the influence of topoisomerase i and gyrase mutations in escherichia coli on the supercoiled density of recombinant plasmids and the stability of left-handed z-dna was investigated. the formation of z-dna in vivo by dc-dg sequences of different lengths was used to determine the effective plasmid supercoil densities in the mutant strains. the presence of z-dna in the cells was detected by linking number and ecori methylase inhibition assays. a change in the unrestrained superhelical tension in vi ... | 1991 | 1846630 |
| myeloperoxidase deficiency as a predisposing factor for deep mucocutaneous candidiasis: a case report. | | 1991 | 1846651 |
| [pediatric bacteremia strains grow in blood culture media]. | bacteremia strains may influence the clinical therapy, the isolation of bacteremia strains is important for patients. in order to understand the distribution and the growth in the blood culture media of bacteremia strains, from january 1982 through december 1988 we studied the blood culture sent to us from the pediatric ward. these were three hundred and forty one bacterial strains (3.1%) isolated from patients. in the meantime we also studied the bacteremia strains growth in the blood culture m ... | 1991 | 1848461 |
| nucleotide sequence of the fixabc region of azorhizobium caulinodans ors571: similarity of the fixb product with eukaryotic flavoproteins, characterization of fixx, and identification of nifw. | the nucleotide sequence of a 4.1 kb dna fragment containing the fixabc region of azorhizobium caulinodans was established. the three gene products were very similar to the corresponding polypeptides of rhizobium meliloti. the c-terminal domains of both fixb products displayed a high degree of similarity with the alpha-subunits of rat and human electron transfer flavoproteins, suggesting a role for the fixb protein in a redox reaction. two open reading frames (orf) were found downstream of fixc. ... | 1991 | 1850088 |