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primary cutaneous histoplasma capsulatum infection in a patient treated with fingolimod: a case report.fingolimod is an immune-modulating drug used in the treatment of multiple sclerosis. histoplasma capsulatum is a dimorphic fungus that can infect humans. infection with the pathogen typically affects the lungs, but it is usually asymptomatic and self-limited. however, immunocompromised patients infected with the pathogen can present atypically, including the development of primary cutaneous lesions. we describe an interesting clinical case of a cutaneous h capsulatum infection in a patient treat ...201728656779
histoplasma capsulatum in the bone marrow of an hiv-infected patient. 201728652215
tonsillar ulceration as manifestation of disseminated african histoplasmosis in an immunocompetent portuguese host.histoplasmosis is a systemic mycosis caused by histoplasma capsulatum. rare in europe but endemic in some regions of brazil, united states, africa and asia. most of the cases are asymptomatic. disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. we report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent portuguese host, as manifestation of disseminated african histoplasmosis 45 years later after liv ...201728626627
rare case of pulmonary histoplasmosis complicated with bronchocentric granulomatosis in a non endemic area.pulmonary histoplasmosis is a fungal infection caused by histoplasma capsulatum, rarely diagnosed in non endemic areas and/or immunocompromised patients. complication of pulmonary histoplasmosis with bronchocentric granulomatosis is extremely rare.201728616380
"polka dot macrophages" on cytology of bilateral adrenal masses-nailing disseminated histoplasmosis.histoplasma capsulatum is a saprophytic fungus that in immunocompetent individuals causes self-limited pulmonary infection; however, in immunosuppressed patients involvement of the reticuloendothelial system, alimentary tract, urinary tract, and central nervous system is fairly common. rarely patients present with bilateral adrenal masses which mimic tuberculosis and metastasis on radiology because of associated central necrosis. ultrasound guided fnac aided by special stains like periodic acid ...201728548709
gastrointestinal histoplasmosis: a case series.histoplasmosis is an invasive mycosis caused by inhalation of the spores of dimorphic fungi histoplasma capsulatum. the disease manifests in the lung as acute or chronic pulmonary histoplasmosis and in severe cases gets disseminated in multiple organs like skin, adrenal gland, central nervous system, lymph node, liver, spleen, bone marrow, and gastrointestinal tract. it occurs most commonly in immunodeficient patients like hiv-positive patients and transplant recipients, while immunocompetent ho ...201728530163
case of disseminated histoplasmosis in a hiv-infected patient revealed by nasal involvement with maxillary osteolysis.disseminated histoplasmosis (dh) is a rare manifestation of acquired immune deficiency syndrome (aids) in european countries. naso-maxillar osteolysis due to histoplasma capsulatum var. capsulatum (hcc) is unusual in endemic countries and has never been reported in european countries. differential diagnoses such as malignant tumors, cocaine use, granulomatosis, vasculitis and infections are more frequently observed and could delay and/or bias the final diagnosis.201728476105
unusual presentation of disseminated histoplasmosis in an immunocompetent patient.disseminated histoplasmosis (dh) is a systemic granulomatous disease caused by the fungus histoplasma capsulatum. this disease occurs mainly in immunocompromised individuals with cd 4 counts less than 200 cell/µl and is rarely noted in immunocompetent person. in india, this disease has been reported from several parts of the country of which most cases are from eastern india which is considered to be endemic for this disease. inhalation of the spores can lead to a self-limiting flulike illness i ...201728474430
seroprevalence of histoplasmosis in somali, burmese, and hmong refugees residing in thailand and kenya.histoplasmosis is known to be endemic to the midwestern united states, but cases have been reported throughout much of the world. somali, hmong, and burmese (ethnically karen) persons make up some of the largest refugee populations coming the united states in recent years. yet, information about risk of histoplasma capsulatum infection amongst these populations is limited. this study used the cdc migrant serum bank to test ~100 samples from each of somali, burmese, and hmong u.s.-bound refugees. ...201728474198
[african histoplamosis. a report of three pediatric cases].histoplasmosis duboisii (histoplasma capsulatum var duboisii) is uncommon disease especially in children. it is observed in africa where the incidence is unknown. the authors report a series of three pediatric cases. the report concerned 2 girls and one boy who were 3, 9 and 4 year-old, respectively. symptoms evolved for more than two months in each case. at admission, we found fever and poor general condition. observed lesions were lymphnodes localisation disseminated (cases 1 and 2), subcutane ...201728462780
african histoplasmosis: new clinical and microbiological insights.african histoplasmosis is defined as the fungal infection caused by histoplasma capsulatum var. duboisii (hcd). studies focused on distinguishing hcd and h. capsulatum var. capsulatum (hcc), which coexist in africa, are scarce or outdated, and african strains are continuously underrepresented. in this work, 13 cases of african patients with histoplasmosis diagnosed in the spanish mycology reference laboratory have been reviewed showing that 77% had disseminated disease and aids as underlying dis ...201728431110
multiple intravitreal ranibizumab injections for persistant choroidal neovascularization associated with presumed ocular histoplasmosis syndrome.presumed ocular histoplasmosis syndrome (pohs) is a clinical entity that is characterized by small, round, discrete, macular or mid peripheral atrophic (punched out) chorioretinal lesions (histo spots), peripapillary scarring, choroidal neovascularization (cnv), and the absence of anterior uveitis and vitritis. diagnosis of this disorder is based upon characteristic clinical findings and a positive histoplasmin skin test or residence in an endemic region for histoplasma capsulatum. there is no a ...201728405488
a case series of histoplasmosis patients with elevated serum soluble interleukin-2 receptor levels.histoplasmosis is a common endemic mycosis that is usually asymptomatic but occasionally results in severe illness. histoplasmosis and its causative agent, histoplasma capsulatum, are found worldwide but rarely in japan. in recent years, however, the number of histoplasmosis patients in japan has increased. in addition, to our knowledge, there are no previous reports of increased serum soluble interleukin-2 receptor (sil-2r) levels in patients with histoplasmosis. we report a case series of hist ...201728395939
[efficacy of the treatment and secondary antifungal prophylaxis in aids-related histoplasmosis. experience at the francisco j. muñiz infectious diseases hospital in buenos aires].classic histoplasmosis is a systemic endemic mycosis due to histoplasma capsulatum var. capsulatum. a significant reduction in the morbidity and mortality of aids-related histoplasmosis has been observed since the introduction of highly active antiretroviral therapy (haart) and secondary antifungal prophylaxis.201728391953
antigenemia without antigenuria in a cat with histoplasmosis.based on demonstration of the yeast phase of histoplasma capsulatum on fine-needle aspirate cytology of the kidney, a 5-year-old cat was diagnosed with histoplasmosis. urine and serum were tested for antigen via a histoplasma antigen enzyme immunoassay. at the time of diagnosis, and on multiple occasions during antifungal treatment, antigenemia was detected without antigenuria. the cat was treated with standard therapy and achieved clinical remission.201728491399
unusual pathogens in hiv positive cases: a report of two cases. 199828775462
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