| osteochondral grafting: effect of graft alignment, material properties, and articular geometry. | osteochondral grafting for cartilage lesions is an attractive surgical procedure; however, the clinical results have not always been successful. surgical recommendations differ with respect to donor site and graft placement technique. no clear biomechanical analysis of these surgical options has been reported. we hypothesized that differences in graft placement, graft biomechanical properties, and graft topography affect cartilage stresses and strains. a finite element model of articular cartila ... | 2009 | 19696917 |
| psychosocial work environment and antidepressant medication: a prospective cohort study. | adverse psychosocial work environments may lead to impaired mental health, but it is still a matter of conjecture if demonstrated associations are causal or biased. we aimed at verifying whether poor psychosocial working climate is related to increase of redeemed subscription of antidepressant medication. | 2009 | 19635130 |
| application of promoter swapping techniques to control expression of chromosomal genes. | the ability to control the expression of chromosomal genes is important for many applications, including metabolic engineering and the functional analysis of cellular processes. this mini-review presents recent work on the application of techniques that allow researchers to replace a chromosomal promoter with one designed for a specific level of activity, thereby exerting precise transcriptional control while retaining the natural genetic context of a gene or operon. this technique, termed promo ... | 2009 | 19633836 |
| [f01wb-1315 a and b, two dihydroorotate dehydrogenase inhibitors from microbial metabolites]. | dihydroorotate dehydrogenase (dhodh) catalyzes the rate-limiting step in pyrimidine biosynthesis, and its inhibitors have been developed as drugs for treatment of immune diseases. we studied new dhodh inhibitors from microbial metabolites. | 2009 | 19621636 |
| space division multiplexing high-birefringence-fiber loop mirrors for discriminative measurement of temperature and strain. | we present a fiber sensor scheme for discriminative measurement of temperature and strain by space division multiplexing high-birefringence-fiber loop mirrors (hbflms). discriminative measurement of temperature and strain can be realized by sequentially measuring the resonance wavelength shifts of two hbflms constructed with the same high-birefringence fiber. experimental results show that the temperature and strain resolutions reach +/-0.5 degrees c and +/-10 microepsilon, respectively. this sc ... | 2009 | 19593352 |
| ebsd characterization of a hot worked 304 austenitic stainless steel under strain reversal. | monotonic and strain reversal hot torsion tests were performed on a 304 austenitic stainless steel, this led to changes in microstructures depending on the strain path. electron backscatter diffraction was used as the tool for characterizing the microstructures. it was possible to find some intragranular microstructural changes due to the reversal of the strain by means of several local and global misorientation-related parameters. sigma3 boundaries also showed sensitivity to strain reversal. | 2009 | 19566625 |
| two-dimensional speckle tracking strain analysis for efficacy assessment of myocardial cell therapy. | the subtle effects of transplanted bone marrow cells (bmc) on regional myocardial behavior in patients with ischemic heart disease are difficult to assess. novel echocardiographic techniques can quantify regional myocardial deformation (strain) and distinguish between passive and active wall motion. we hypothesized that this technique may help delineate cell therapy-induced changes in regional lv contractility that escape clinical routine studies. twelve patients with coronary artery disease and ... | 2009 | 19558784 |
| left ventricle longitudinal deformation assessment by mitral annulus displacement or global longitudinal strain in chronic ischemic heart disease: are they interchangeable? | increasing infarct mass is associated with impaired prognosis in chronic ischemic heart disease. global strain by echocardiographic assessment relates closely to infarct mass assessed by delayed enhancement magnetic resonance imaging but requires deformation analysis in a 16-segment model of the left ventricular. mitral annular (ma) displacement reflects longitudinal left ventricular deformation and could provide similar information. | 2009 | 19505792 |
| impact of left ventricular size on tissue doppler and longitudinal strain by speckle tracking for assessing wall motion and mechanical dyssynchrony in candidates for cardiac resynchronization therapy. | myocardial dysfunction and left ventricular (lv) geometry deformation may reduce the accuracy of tissue doppler imaging (tdi) in assessing myocardial contractility. | 2009 | 19501329 |
| clinical assessment of left ventricular rotation and strain: a novel approach for quantification of function in infarcted myocardium and its border zones. | left ventricular (lv) circumferential strain and rotation have been introduced as clinical markers of myocardial function. this study investigates how regional lv apical rotation and strain can be used in combination to assess function in the infarcted ventricle. in healthy subjects (n = 15) and patients with myocardial infarction (n = 23), lv apical segmental rotation and strain were measured from apical short-axis recordings by speckle tracking echocardiography (ste) and mri tagging. infarct e ... | 2009 | 19395547 |
| shape transitions of epitaxial islands during strained layer growth: anatase tio2(001) on srtio3(001). | extended annealing in uhv causes the surface region of srtio3(001) to become enriched with tio2, resulting in the formation of epitaxial islands of anatase tio2(001). the islands are studied using uhv scanning electron microscopy (sem), which reveals the changes in morphology during growth induced by misfit strain. starting from a square island, two types of shape transition are observed. in the first, between 1000 and 1030 degrees c, the anatase islands elongate in length and narrow in width. t ... | 2009 | 19392457 |
| diagnostic capability and reproducibility of strain by doppler and by speckle tracking in patients with acute myocardial infarction. | the objective of the present study was to investigate the ability of strain by doppler and by speckle tracking echocardiography in the acute phase in patients with st-segment elevation myocardial infarction (stemi) to diagnose left ventricular (lv) infarct size. furthermore, we wanted to study at which time during the cardiac cycle strain should be measured. | 2009 | 19356529 |
| exploring the association between functional strain and emotional well-being among a population-based sample of breast cancer survivors. | breast cancer survival and survivorship outcomes have improved dramatically; yet, there are still considerable morbidities associated with this illness. functional strain is conceptualized as the unfavorable outcome of the functional well-being domain of health-related quality of life. this study intends to (1) examine the adequacy of the functional strain concept; (2) describe the level of functional strain and emotional well-being by ethnicity and job types; and (3) investigate the salient fun ... | 2010 | 19253917 |
| [comparison of radial two-dimensional strain and regional wall motion abnormalities in the patients undergoing off-pump coronary artery bypass grafting]. | measurement of myocardial strain by echocardiogram is a novel approach in quantitatively assessing regional ventricular function. we investigated the relationship between left ventricular radial strain and traditional visual assessment of regional wall motion abnormalities. | 2009 | 19227164 |
| race and financial strain are independent correlates of sleep in midlife women: the swan sleep study. | to examine racial differences in sleep in a large cohort of midlife women and to evaluate whether indices of socioeconomic status (ses) are associated with racial differences in sleep. | 2009 | 19189781 |
| a multiscale computational comparison of the bicuspid and tricuspid aortic valves in relation to calcific aortic stenosis. | patients with bicuspid aortic valve (bav) are more likely to develop a calcific aortic stenosis (cas), as well as a number of other ailments, as compared to their cohorts with normal tricuspid aortic valves (tav). it is currently unknown whether the increase in risk of cas is caused by the geometric differences between the tricuspid and bicuspid valves or whether the increase in risk is caused by the same underlying factors that produce the geometric difference. cas progression is understood to ... | 2008 | 18996528 |
| effect of preload on left ventricular longitudinal strain by 2d speckle tracking. | peak systolic longitudinal strain (psls) obtained using the 2d speckle tracking method is a novel indicator of the long-axis function of the left ventricle (lv). we used the 2d strain profile to examine the effect of preload reduction by hemodialysis (hd) on lv psls in patients with end-stage renal disease (esrd). | 2008 | 18986415 |
| stable, intelligible ultrasonic strain imaging. | background: freehand quasistatic strain imaging can reveal qualitative information about tissue stiffness with good spatial accuracy. clinical trials, however, repeatedly cite instability and variable signal-to-noise ratio as significant drawbacks. methods: this study investigates three post-processing strategies for quasistatic strain imaging. normalisation divides the strain by an estimate of the stress field, the intention being to reduce sensitivity to variable applied stress. persistence ai ... | 2008 | 21151829 |
| left atrial velocity vector imaging for the detection and quantification of left ventricular diastolic function in type 2 diabetes. | left ventricular (lv) diastolic dysfunction (dd) is diagnosed by doppler echocardiography (de) and tissue doppler imaging (tdi). velocity vector imaging (vvi) evaluates myocardial deformation (strain). we studied left atrial (la) deformation and volumes by vvi in relation to established doppler-derived indices of lv diastolic function in diabetic patients. | 2008 | 18838296 |
| nanogroove formation by ion irradiation on indentation-modified amorphous sio(2). | ion beams are widely used for micro/nanostructure fabrication with unique features of the energetic processes. in this work, we present a self-assembled nanostructure fabrication by ion irradiation with a patterned strain/stress field. the patterned strain/stress field is introduced by micro-vickers indentation to amorphous sio(2) (load = 100 mn). after irradiation of 60 kev cu(-) ions, nanogrooves (width from 150 to 250 nm) were created at the indentation edge. under the ion irradiation of a co ... | 2008 | 21832550 |
| the effects of 1,4-benzoquinone on c-myb and topoisomerase ii in k-562 cells. | exposure to benzene, a ubiquitous environmental pollutant, has been linked to leukemia, although the mechanism of benzene-initiated leukemogenesis remains unclear. benzene can be bioactivated to toxic metabolites such as 1,4 benzoquinone (bq), which can alter signaling pathways and affect chromosomal integrity. bq has been shown to increase the activity of c-myb, which is an important transcription factor involved in hematopoiesis, cell proliferation, and cell differentiation. the c-myb protein ... | 2008 | 18778717 |
| lambdan gene expression regulated by translation termination in ribosome l24 mutant. | besides transcription regulation, gene expression is also regulated at translation level. although translation regulation is mainly mediated by translation initiation, an abundance of evidence shows that the termination phase of translation is also important for gene expression. the expression of lambdan gene is down regulated at translation level in l24 mutant, however the precise mechanism still remains unknown. we report here that in an l24 mutant strain, the expression of lac-lambdan and gst ... | 2003 | 18758703 |
| longitudinal strain delay index by speckle tracking imaging: a new marker of response to cardiac resynchronization therapy. | in heart failure patients with left ventricular dyssynchrony, contractility in delayed segments does not fully contribute to end-systolic function. we quantified this reserve of contraction related to mechanical dyssynchrony to predict response to cardiac resynchronization therapy by the strain delay index, which was defined as the sum of the difference between peak and end-systolic strain across 16 segments. | 2008 | 18725491 |
| a phospholipid-modified polystyrene-polyisobutylene-polystyrene (sibs) triblock polymer for enhanced hemocompatibility and potential use in artificial heart valves. | poly(styrene-block-isobutylene-block-styrene) ('sibs') is selected for a novel tri-leaflet heart valve due to its high resistance to oxidation, hydrolysis, and enzyme attack. sibs is modified using six different phospholipids and its mechanical properties characterized by tensile stress, peel strength, shear strength, contact angle, and surface energy, and then for hemocompatibility by studying the adhesion of fluorescently labeled platelets in a parallel plate chamber under physiological flow c ... | 2009 | 18697881 |
| [qualitative investigation into the strain endured by breast cancer patients in initial in-patient therapy]. | in-patient hospital stays and primary breast cancer operations put a strain on the affected women, about which little is known to date. in order to gain a better understanding of this stress situation, 42 primary operated breast cancer patients were surveyed in qualitative interviews during their in-patient hospital stay. besides suffering from existential anxieties and uncertainties, typical stresses for the perioperative area are the fear of the anaesthesia and operation, the uncertainty felt ... | 2008 | 18552116 |
| filter paper degrading ability of a trichoderma strain with multinucleate conidia. | the multinucleate conidia were produced from the green mature conidia of trichoderma reesei rut c-30 strain by colchicine treatment. the strain with higher filter paper degrading ability was selected among those conidia using a double layer selection medium. the selected strain, js-2 was able to collapse the filter paper within 15 min but the original strain took 25 min to collapse it completely. moreover, the amount of reducing sugar in the l-type glass tube of the strain, js-2 was greater than ... | 2007 | 18478384 |
| 3d myocardial tissue tracking with slice followed cine dense mri. | to track three-dimensional (3d) myocardial tissue motion using slice followed cine displacement encoded imaging with stimulated echoes (dense). | 2008 | 18425823 |
| purification and biochemical characterization of extracellular beta-glucosidases from the hypercellulolytic pol6 mutant of penicillium occitanis. | the pol6 mutant of penicillium occitanis fungus is of great biotechnological interest since it possesses a high capacity of cellulases and beta-glucosidase production with high cellulose degradation efficiency (jain et al., enzyme microb technol, 12:691-696, 1990; hadj-taieb et al., appl microbiol biotechnol, 37:197-201, 1992; ellouz chaabouni et al., enzyme microb technol, 16:538-542, 1994; ellouz chaabouni et al., appl microbiol biotechnol, 43:267-269, 1995). in this work, two forms of beta-gl ... | 2008 | 18401747 |
| neck muscle strain when wearing helmet and nvg during acceleration on a trampoline. | the helmet-mounted equipment worn by military pilots increases the weight of the helmet system and shifts its center of gravity, increasing the loads on neck structures, especially during acceleration. the aim of this study was to determine neck muscle strain with different head-loads during trampoline-induced g loads (0 to +4 g). | 2008 | 18309908 |
| [influence of rescue service personnel's shift work on psycho-physical parameters]. | the aim of the investigation was to receive information about the interaction between psycho-physical parameters as a function of the strain by shift work for rescue service personnel. | 2008 | 18092281 |
| nanostructured bulk copper fabricated by accumulative roll bonding. | in this study, we tried to fabricate the nanostructured bulk copper alloys by a severe plastic deformation process. the sheets of copper alloys (ofc, pmc90, and dlp) were heavily deformed to an equivalent strain of 6.4 by the accumulative roll-bonding (arb) process. the microstructure and the mechanical property of the fabricated specimens were systematically investigated. the microstructure was finely subdivided with increasing the equivalent strain by the arb process. the severely deformed cop ... | 2007 | 18047101 |
| the role of flexible polymer interconnects in chronic tissue response induced by intracortical microelectrodes--a modeling and an in vivo study. | chronic tissue response induced by tethering is one of the major causes for implant failure in intracortical microelectrodes. in this study, we had explored the hypothesis that flexible interconnects could provide strain relief against forces of "micromotion" and hence could result in maintaining a healthy tissue surrounding the implant. finite element modeling results indicated that flexible interconnects, namely polyimide (e=2 gpa) and polydimethylsiloxane (pdms, e=6 mpa), reduced the interfac ... | 2006 | 17947041 |
| lv systolic impairment in patients with asymptomatic coronary heart disease and type 1 diabetes is related to coronary atherosclerosis, glycaemic control and advanced glycation endproducts. | to evaluate whether heart failure in type 1 diabetes is linked to poor glycaemic control, coronary atherosclerosis or advanced glycation endproducts (ages). | 2007 | 17719271 |
| aldosterone receptor antagonism induces reverse remodeling when added to angiotensin receptor blockade in chronic heart failure. | the objective of this study was to determine if adding spironolactone to an angiotensin ii receptor blocker improves left ventricular (lv) function, mass, and volumes in chronic heart failure. | 2007 | 17692742 |
| subthreshold coexistence of strains: the impact of vaccination and mutation. | we consider a model for a disease with two competing strains and vaccination. the vaccine provides complete protection against one of the strains (strain 2) but only partial protection against the other (strain 1). the partial protection leads to existence of subthreshold equilibria of strain 1. if the first strain mutates into the second, there are subthreshold coexistence equilibria when both vaccine-dependent reproduction numbers are below one. thus, a vaccine that is specific toward the seco ... | 2007 | 17658928 |
| strong luminescence from strain relaxed ingan/gan nanotips for highly efficient light emitters. | semiconductor heterostructures represent the most important building block for current optoelectronic devices. one of the common features of semiconductor heterostructures is the existence of internal strain due to lattice mismatch. the internal strain can tilt the band alignment and significantly alter the physical properties of semiconductor heterostructures, such as reducing the internal quantum efficiency of a light emitter. here, we provide a convenient route to release the internal strain ... | 2007 | 19547278 |
| sensing of multimode-fiber strain by a dynamic photorefractive hologram. | we present a strain sensor in which a multimode fiber is used as a sensitive element. high sensitivity to dynamic strains is achieved by means of vectorial wave mixing in a photorefractive cdte:v crystal. it was found that the largest source of noise in our sensor is related to the instability of the polarization state of speckles emerging from the fiber. this noise is significantly diminished in fiber with a core of large diameter (550 microm). | 2007 | 17603581 |
| transesophageal tissue doppler echocardiography for evaluation of myocardial function during aortic valve replacement. | tissue doppler imaging is an evolving ultrasound technology that, compared with traditional echocardiography, promises reduced subjectivity in the assessment of myocardial performance and contributes new information on myocardial function. the aim of this study was to evaluate the feasibility of transesophageal tissue doppler imaging in the setting of aortic valve replacement. | 2007 | 17544887 |
| impact of left ventricular loading conditions on myocardial deformation parameters: analysis of early and late changes of myocardial deformation parameters after aortic valve replacement. | myocardial deformation imaging is used to assess regional left ventricular (lv) function. we sought to define the impact of changes in lv loading conditions on myocardial deformation parameters. aortic valve replacement in patients with different aortic valve pathologies was used as a model to assess the impact of preload and afterload changes. in 53 patients scheduled for aortic valve replacement serial echocardiographic studies were performed preoperatively and postoperatively (within 7 days a ... | 2007 | 17543737 |
| global longitudinal strain by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease. | | 2007 | 17542782 |
| early prediction of infarct size by strain doppler echocardiography after coronary reperfusion. | the objective of this study was to investigate whether strain doppler echocardiography performed immediately after revascularization by percutaneous coronary intervention could predict the extent of myocardial scar, determined by contrast-enhanced magnetic resonance imaging (mri). | 2007 | 17448374 |
| interrogation of fiber bragg-grating resonators by polarization-spectroscopy laser-frequency locking. | we report on an optically-based technique that provides an efficient way to track static and dynamic strain by locking the frequency of a diode laser to a fiber bragg-grating fabry-pérot cavity. for this purpose, a suitable optical frequency discriminator is generated exploiting the fiber natural birefringence and that resulting from the gratings inscription process. in our scheme, a polarization analyzer detects dispersive-shaped signals centered on the cavity resonances without need for additi ... | 2007 | 19532618 |
| examination of aerodynamic measures and strain by vibratory source. | patients with laryngotracheal stenosis often require airway reconstruction. following surgical intervention, voicing may be produced with either a glottic or supraglottic vibratory source. the objective of this study was to compare average airflow, estimated subglottal pressure, and expert perceptual rating of strain between children with glottic and supraglottic vibratory sources post-airway reconstruction. | 2007 | 17321877 |
| acute left ventricular dyssynchrony improvement predicts long-term benefit from cardiac resynchronization therapy. | to evaluate the relationship between acute response to cardiac resynchronization therapy (crt) and long-term clinical outcome in patients with drug refractory heart failure. | 2007 | 17302720 |
| working conditions, adverse events and mental health problems in a sample of 949 german teachers. | the aim of this study was (1) to explore in detail the working load of teachers, (2) to analyse the extent of negative or threatening school-related events teachers are confronted with, and (3) to evaluate mental health strain by applying the general health questionnaire (ghq). | 2007 | 17294238 |
| quantitative trait locus mapping for acute functional tolerance to ethanol in the l x s recombinant inbred panel. | acute functional tolerance (aft) develops shortly after ethanol administration, and is determined as the change in brain or blood ethanol concentration (bec) measured at 2 behavioral or physiological endpoints. acute functional tolerance studies in some rodent strains support a long-held hypothesis that more sensitive strains develop more within-session tolerance. we used the new, 74-strain l x s recombinant inbred (ri) panel, developed from inbred long-sleep (ils) and inbred short-sleep (iss) s ... | 2007 | 17250610 |
| an apparent paradox of horizontal and vertical disease transmission. | the question as to how the ratio of horizontal to vertical transmission depends on the coefficient of horizontal transmission is investigated in host-parasite models with one or two parasite strains. in an apparent paradox, this ratio decreases as the coefficient is increased provided that the ratio is taken at the equilibrium at which both host and parasite persist. moreover, a completely vertically transmitted parasite strain that would go extinct on its own can coexist with a more harmful hor ... | 2007 | 22880612 |
| local elasticity imaging of vulnerable atherosclerotic coronary plaques. | the material composition and morphology of vulnerable atherosclerotic plaque components are considered to be more important determinants of acute coronary syndromes than the degree of stenosis. rupture of a plaque causes thrombogenic material to contact the blood, resulting in a thrombus. rupture-prone plaques contain an inflamed thin fibrous cap covering a large soft lipid pool. mechanically, rupture occurs when plaques cannot withstand the internal stresses induced by the pulsating blood. thes ... | 2007 | 17075198 |
| dynamics of fracture in drying suspensions. | we investigate the dynamics of fracture in drying films of colloidal silica. water loss quenches the nanoparticle dispersions to form a liquid-saturated elastic network of particles that relieves drying-induced strain by cracking. these cracks display intriguing intermittent motion originating from the deformation of arrested crack tips and aging of the elastic network. the dynamics of a single crack exhibits a universal evolution, described by a balance of the driving elastic power with the sum ... | 2006 | 16893207 |
| motion compensation for intravascular ultrasound palpography. | rupture of vulnerable plaques in coronary arteries is the major cause of acute coronary syndromes. most vulnerable plaques consist of a thin fibrous cap covering an atheromous core. these plaques can be identified using intravascular ultrasound (ivus) palpography, which measures radial strain by cross-correlating rf signals at different intraluminal pressures. multiple strain images (i.e., partial palpograms) are averaged per heart cycle to produce a more robust compounded palpogram. however, ca ... | 2006 | 16889334 |
| deviatoric stress: a nuisance or a gold mine? | both synchrotron radiation and deviatoric stress were once considered to be nuisances. now synchrotron radiation is one of the most important tools available to scientists of all disciplines and deviatoric stress is one of the most useful aspects of x-ray diffraction at extreme conditions. samples in high-pressure devices are under true hydrostatic pressure only when surrounded by a fluid, thus limiting true hydrostatic pressure studies at ambient temperatures to pressures below about 11 gpa. el ... | 2006 | 22611102 |
| elastically relaxed free-standing strained-silicon nanomembranes. | strain plays a critical role in the properties of materials. in silicon and silicon-germanium, strain provides a mechanism for control of both carrier mobility and band offsets. in materials integration, strain is typically tuned through the use of dislocations and elemental composition. we demonstrate a versatile method to control strain by fabricating membranes in which the final strain state is controlled by elastic strain sharing, that is, without the formation of defects. we grow si/sige la ... | 2006 | 16604081 |
| kinetic substituent and solvent effects in 1,3-dipolar cycloaddition of diphenyldiazomethanes with fullerenes c60 and c70: a comparison with the addition to tcne, ddq, and chloranil. | kinetics of 1,3-dipolar cycloaddition of a series of meta- and para-substituted diphenyldiazomethanes (ddms) with fullerenes c60 and c70 as dipolarophiles have been investigated in toluene at 30 degrees c. fullerene c60 was ca. 1.5 times more reactive than c70. the rate constants (k) for the primary [3 + 2] additions increased with the increase of the electron-releasing ability of the meta and para substituent. the log k/k0 values were well correlated by the yukawa-tsuno (y-t) equations with the ... | 2006 | 16599593 |
| effect of long-term cocaine use on regional left ventricular function as determined by magnetic resonance imaging. | this study examined left ventricular (lv) regional midwall circumferential strain by cardiac tagged magnetic resonance imaging in 32 long-term cocaine users and 14 nonusers. most of the lv segmentations in the cocaine users had less average circumferential strain in the systolic and diastolic phases. the average diastolic strain in 5 ventricular segmentations was significantly less in the cocaine users (p<0.05). in conclusion, long-term cocaine use may be associated with regional lv dysfunction, ... | 2006 | 16563922 |
| accuracy, reproducibility, and comparability of doppler tissue imaging by two high-end ultrasound systems. | doppler tissue imaging is a new technology for quantitative evaluation of myocardial motion and contractility, and is available in several ultrasound systems. this study evaluates the comparability, accuracy, and reproducibility of measurements of velocity, strain rate, and strain by two high-end ultrasound systems. | 2006 | 16500496 |
| a secondary disruption of the dmpa gene encoding a large membrane protein allows aggregation defective dictyostelium rasc- cells to form multicellular structures. | the disruption of the gene encoding the dictyostelium ras subfamily protein, rasc, results in a strain that does not aggregate and has defects in both camp signal relay and camp chemotaxis. disruption of a second gene in the rasc(-) strain by restriction enzyme mediated integration produced cells that were capable of forming multicellular structures in plaques on bacterial lawns. the disrupted gene (dmpa) encoded a novel membrane protein that was designated dmp1. although the rasc(-)/dmpa(-) cel ... | 2006 | 16490188 |
| strain improvement studies on production of cephalosporin c from acremonium chrysogenum atcc 48272. | strain development for antibiotic production has been an essential prerequistie for efficient production process. studies were carried out to produce high antibiotic yield strain by using uv and n-methyl-n1-nitro-nitrosoguanidine (ntg) as mutagens. a superior mutant (pntg-22) with a productivity of 2.4 time (810-1995 microg/ml higher than, the parent strain was produced. | 2012 | 16281823 |
| constrained rouse model of rubber viscoelasticity. | in this work we use a new approach to investigate the equilibrium and linear dynamic-mechanical response of a polymer network. the classical rouse model is extended to incorporate quenched constraints on its end-boundary conditions; a microscopic stress tensor for the network system is then derived in the affine deformation limit. to test the model we calculate the macroscopic stress in equilibrium, corresponding to the long-time limit of relaxation. particular attention is paid to the treatment ... | 2005 | 16080758 |
| electrochemical behavior of the tris(pyridine)-cu funnel complexes: an overall induced-fit process involving an entatic state through a supramolecular stress. | the electrochemical behavior of the tris(pyridine) calix[6]arene cu adducts is unique as compared to that of most classical cu complexes in a strain-free environment. the presence of mecn buried inside the cavity is a prerequisite for a quasi-reversible behavior in a dynamic mode. the cv behavior assisted by simulation outlines that the coordination adaptability of the cu(ii)/cu(i) redox states is completely reversed, with a td geometry enforced at either redox states. hence, the supramolecular ... | 2005 | 15826140 |
| adaptive spectral strain estimators for elastography. | in conventional elastography, internal tissue deformations, induced by external compression applied to the tissue surface, are estimated by cross-correlation analysis of echo signals obtained before and after compression. conventionally, strains are estimated by computing the gradient of estimated displacement. however, gradient-based algorithms are highly susceptible to noise and decorrelation, which could limit their utility. we previously developed strain estimators based on a frequency-domai ... | 2004 | 15754795 |
| volume-based non-continuum modeling of bone functional adaptation. | bone adapts to mechanical strain by rearranging the trabecular geometry and bone density. the common finite element methods used to simulate this adaptation have inconsistencies regarding material properties at each node and are computationally demanding. here, a volume-based, non-continuum formulation is proposed as an alternative. adaptive processes corresponding to various external mechanical loading conditions are simulated for the femur. | 2005 | 15733328 |
| [breathing difficulties and asthma prevalence in children from zero to five years of age in five rom settlements]. | to study the relation between living conditions in temporary rom settlements and asthma prevalence in children. | 2015 | 15732680 |
| detection of surface strain by three-dimensional digital holography. | three-dimensional digital holography with three object-illuminating beams has been successfully used for the detection of surface strain in metallic objects. the optical setup that uses illuminating beams to irradiate the object from three directions means that all three object surface displacement components, x, y, and z, can be independently calculated and used to find the strain gradients on the surface. the results show the conversion of the complete surface displacement field into a surface ... | 2005 | 15662881 |
| job strain in relation to ambulatory blood pressure, heart rate, and heart rate variability among female nurses. | this study examined the effects of exposure to job strain on independent predictors of cardiovascular disease (ambulatory blood pressure, heart rate, and heart rate variability). | 2004 | 15635758 |
| thin bio-artificial tissues in plane stress: the relationship between cell and tissue strain, and an improved constitutive model. | constitutive models are needed to relate the active and passive mechanical properties of cells to the overall mechanical response of bio-artificial tissues. the zahalak model attempts to explicitly describe this link for a class of bio-artificial tissues. a fundamental assumption made by zahalak is that cells stretch in perfect registry with a tissue. we show this assumption to be valid only for special cases, and we correct the zahalak model accordingly. we focus on short-term and very long-ter ... | 2005 | 15596492 |
| the relationship between cell and tissue strain in three-dimensional bio-artificial tissues. | continuum constitutive laws are needed to ensure that bio-artificial tissue constructs replicate the mechanical response of the tissues they replace, and to understand how the constituents of these constructs contribute to their overall mechanical response. one model designed to achieve both of these aims is the zahalak model, which was modified by marquez and co-workers to incorporate inhomogeneous strain fields within very thin tissues. when applied to reinterpret previous measurements, the mo ... | 2005 | 15596491 |
| a molecular spring for vision. | light absorption by the visual pigment rhodopsin leads to vision via a complex signal transduction pathway that is initiated by the ultrafast and highly efficient photoreaction of its chromophore, the retinal protonated schiff base (rpsb). here, we investigate this reaction in real time by means of unrestrained molecular dynamics simulations of the protein in a membrane mimetic environment, treating the chromophore at the density functional theory level. we demonstrate that a highly strained all ... | 2004 | 15563129 |
| detection of ischemia and new insight into left ventricular physiology by strain doppler and tissue velocity imaging: assessment during coronary bypass operation of the beating heart. | detection of myocardial ischemia in humans by strain doppler and tissue velocity imaging was validated in a novel, experimentally designed study model during coronary bypass operation of the beating heart. | 2004 | 15562259 |
| [analysis of the mechanism involved in the neuroendocrine-related gene expression in a small cell lung carcinoma cell strain by correlation profiling of cdna array data]. | | 2004 | 15540659 |
| a taylor vortex analogy in granular flows. | fluids sheared between concentric rotating cylinders undergo a series of three-dimensional instabilities. since taylor's archetypal 1923 study, these have proved pivotal to understanding how fluid flows become unstable and eventually undergo transitions to chaotic or turbulent states. in contrast, predicting the dynamics of granular systems--from nano-sized particles to debris flows--is far less reliable. under shear these materials resemble fluids, but solid-like responses, non-equilibrium stru ... | 2004 | 15386007 |
| dependence of the brillouin frequency shift on strain and temperature in a photonic crystal fiber. | the dependence of the brillouin frequency shift on strain in a photonic crystal fiber (pcf) was measured at a wavelength of 1320 nm for the first time to the authors' knowledge. together with measurements of the dependence of the brillouin frequency shift on temperature in the pcf, we demonstrate the feasibility of the highly precise simultaneous measurement of temperature and strain by use of the pcf in a distributed brillouin sensing system with a spatial resolution of 15 cm. | 2004 | 15259721 |
| osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain. | in vivo, bones' osteogenic response to mechanical loading involves proliferation of surface osteoblasts. this response is replicated in vitro and involves erk-mediated activation of the estrogen receptor (er) alpha and upregulation of estrogen response element activity. this proliferative response can be blocked by selective estrogen receptor modulators and increased by transfection of additional eralpha. | 2004 | 15190886 |
| a comparison of 2 rehabilitation programs in the treatment of acute hamstring strains. | prospective randomized comparison of 2 rehabilitation programs. | 2004 | 15089024 |
| a novel approach to improve specificity of algal biosensors using wild-type and resistant mutants: an application to detect tnt. | a new genetic approach was developed for increasing specificity of microalgal biosensors. this method is based on the use of two different genotypes jointly to detect a given pollutant: (i) a sensitive genotype to obtain sensitivity; and (ii) a resistant mutant to obtain specificity. the method was tested by the development of a microalgal biosensor for the detection of the explosive 2,4,6-trinitrotoluene (tnt) using a wild-type strain (dcg1wt) of dictyosphaerium chlorelloides (chlorophyceae) as ... | 2004 | 15046765 |
| forgotten voices: lessons from bereaved caregivers of persons with a brain tumour. | although investigators have identified rewards and difficulties from assuming the role of caregiver for persons with cancer and persons with alzheimer's disease, few studies have examined factors that lead to role strain for caregivers of persons with both oncological and neurological symptoms. in this study qualitative methods were used to analyse data from self-report questionnaires from 43 caregivers of adults with a primary malignant brain tumour (pmbt) in the usa. six themes emerged from th ... | 2004 | 15039610 |
| pcr-based ribosomal dna detection technique for microalga (heterosigma carterae) causing red tide and its application to a biosensor using labeled probe. | a technique for detecting raphidophycean, a bloom-forming genus of algae, was developed using a specific dna probe. the design of the probe was based on a sequence polymorphism within the small subunit (ssu) ribosomal rna gene (rdna) of this strain by using fluorescence polarization (fp) analysis and the biacore 2000 biosensor, which utilized surface plasmon resonance (spr). the specific sequence in ssu rdna for heterosigma carterae was determined by sequence data analysis. one pair of polymeras ... | 2010 | 14730424 |
| chromosome substitution strains: some quantitative considerations for genome scans and fine mapping. | a chromosome substitution strain (css) is an inbred strain in which one chromosome has been substituted from a different inbred strain by repeated backcrossing. a complete css set has one strain representing each chromosome against a uniform background, thus allowing genome-wide scans to be carried out for quantitative trait loci (qtls) influencing any trait of interest. a one-way anova by strain is first carried out, followed by planned comparisons using dunnett's method. a qtl is detected and ... | 2003 | 14722722 |
| effect of lithotomy positions on strain of the obturator and lateral femoral cutaneous nerves. | the purpose of this study was to determine if various lithotomy positions increase strain on the obturator and lateral femoral cutaneous nerves in fresh adult cadavers. a static load cell was used to record strain changes of the obturator and lateral femoral cutaneous nerves in the pelvis and anterior thigh when the lower limbs were placed in three sets of positions of varying hip abduction and flexion. the means of the strain measurements, which were measured in grams in all positioning angles ... | 2004 | 14695587 |
| genetic architecture of fast- and slow-twitch skeletal muscle weight in 200-day-old mice of the c57bl/6j and dba/2j lineage. | the aim of the study was to explore the genetic architecture influencing weight of fast- and slow-twitch skeletal muscles. the weights of the slow-twitch soleus, the mixed gastrocnemius, the fast-twitch tibialis anterior (ta), and extensor digitorum longus (edl) muscles were 11-34% greater (p < 0.001) in 200-day-old c57bl/6j (b6) than in dba/2j (d2) mice. male muscles were 13-28% larger than female (p < 1 x 10(-5), no strain by sex interaction). the sex-related difference in muscle weight, howev ... | 2003 | 14679300 |
| [simulation of bone strain by orthodontic implants using the finite element method]. | load direction of applied forces, implant geometry and other biomechanical parameters lead to varying reactions in the surrounding bone structure. three types of endosseous implant measuring 9 mm in length and 3.3 mm in diameter with and without superperiosteal step, and a threaded surface were investigated with the aid of a finite element method using the cosmos/m 2.5 program. the load on the implant was investigated under vertical, horizontal, and diagonal forces of between 0.01 n and 100 n. v ... | 2003 | 14606270 |
| stress/strain/life revisited. quantification by blood pressure chronomics: benetensive, transtensive or maletensive chrono-vasculo-neuro-immuno-modulation. | we propose to initiate the automatic self-assessment of wear and tear as "stress and strain" by the time structures of blood pressure (bp) and heart rate (hr), in order to arrive eventually at an individualized timely and timed routine of life and to early preventive intervention as soon as needed. the routine may involve physiological scheduling of physical and mental activities and meals, and if need be of non-drug or drug treatment for stress amplification, e.g., by exercise, and/or strain (n ... | 2003 | 14572690 |
| the effects of compressive load and knee joint torque on peak anterior cruciate ligament strains. | high graft strains incurred during rehabilitation after anterior cruciate ligament reconstruction may be minimized if an external compressive load is simultaneously applied to the joint during closed kinetic chain exercises. | 2017 | 12975189 |
| three novel hydroxybenzoate saxitoxin analogues isolated from the dinoflagellate gymnodinium catenatum. | in a recent survey of paralytic shellfish poisoning (psp) toxins in gymnodinium catenatum graham extracts, using lc with postcolumn oxidation and fluorescence detection, three novel saxitoxin analogues were revealed in isolates from several locations, including australian waters. we have named them as g. catenatum toxins, gc1 (1), gc2 (2), and gc3 (3). the compounds were isolated from a culture of the australian strain by lc-ms-guided fractionation employing a c18-silica column and hydrophilic i ... | 2003 | 12924931 |
| [inhibition by ctla-4ig on herpetic stromal keratitis in a murine model]. | to investigate the inhibition by ctla-4ig on herpetic stromal keratitis (hsk). | 2003 | 12880576 |
| vastus lateralis strain associated with patellofemoral pain syndrome: a report of 2 cases. | muscle strains of the quadriceps group are common, and occur mostly in the rectus femoris. strains occur most often when muscles are suddenly activated while on stretch, during either eccentric or concentric contraction. we report 2 cases of vastus lateralis strain that occurred in association with clinical histories of patellofemoral pain syndrome. symptoms described included anterior knee pain associated with prolonged sitting with the knee flexed, and anterior knee pain associated with runnin ... | 2003 | 12690602 |
| rearrangements in hard-sphere glasses under oscillatory shear strain. | we investigate particle rearrangements in colloidal glasses subjected to oscillatory shear strain by the technique of light scattering (ls) echo. ls echo directly follows the motion of the particles through peaks (echoes) in the intensity autocorrelation function; the height of the peak measures the reversible motion in the sample. polydisperse hard-sphere poly-methylmethacrylate particles were used to avoid crystallization under shear. the yielding behavior is monitored through irreversible par ... | 2002 | 12513487 |
| dual temperature and strain measurement with the combined fluorescence lifetime and bragg wavelength shift approach in doped optical fiber. | we have constructed fiber-optic sensors to measure temperature and strain by combining the properties of fiber bragg gratings with the fluorescent lifetimes of various doped fibers. sensors have been made with the fiber bragg grating written directly into the doped fiber to ensure the collocation of the strain and temperature measurement points. results are compared with those obtained previously from a bragg grating written into standard photosensitive fiber spliced to doped fiber. standard dev ... | 2002 | 12412649 |
| different age-specific demographic profiles are generated in the same normal-lived drosophila strain by different longevity stimuli. | we review the empirical data obtained with our normal-lived ra control strain of drosophila and show that this one genome is capable of invoking at least three different responses to external stimuli that induce the animal to express one of three different extended longevity phenotypes, each of which arises from one of three different antagonistic molecular mechanisms of stress resistance. the phenotypes are distinguished by different age-specific mortality patterns. depending on the selected me ... | 2002 | 12403794 |
| parenting in a crisis: conceptualising mothers of children with cancer. | much research on the experiences of parents of children with cancer has been conducted within a discourse of psycho-pathology, or has tended to see parents mostly as a proxy source of information on the well-being of their children. using empirical data from semi-structured interviews with 20 mothers of a child with cancer, in one area of the uk, we draw on sociological literatures on motherhood, childhood, caring, and chronic illness to suggest a more helpful and informative way of understandin ... | 2002 | 12383468 |
| mast cells: a cellular link between autoantibodies and inflammatory arthritis. | previous studies have revealed that autoantibodies, complement components, and fc receptors each participate in the pathogenesis of erosive arthritis in k/bxn mice. however, it is not known which cellular populations are responsive to these inflammatory signals. we find that two strains of mice deficient in mast cells, w/wv and sl/sld, were resistant to development of joint inflammation and that susceptibility was restored in the w/wv strain by mast cell engraftment. thus, mast cells may functio ... | 2002 | 12215644 |
| simulated graft recession in endoscopic acl reconstruction: influence on graft strain. | eight fresh cadaveric knee specimens underwent arthroscopic-assisted acl reconstruction to examine the influence of femoral graft recession on graft strain pattern. length changes between tibial origin and femoral insertion (simulating graft strain or isometry pattern) were measured throughout knee motion (0 degrees-90 degrees) with a simulated acl construct. measurements were taken at the "endo" position (replicating the normal endoscopic position) and in progressive 1.5-mm increments proximall ... | 2002 | 12152974 |
| quantitative assessment of intrinsic regional myocardial deformation by doppler strain rate echocardiography in humans: validation against three-dimensional tagged magnetic resonance imaging. | tissue doppler echocardiography-derived strain rate and strain measurements (sde) are new quantitative indices of intrinsic cardiac deformation. the aim of this study was to validate and compare these new indices of regional cardiac function to measurements of 3-dimensional myocardial strain by tagged mri. | 2002 | 12093769 |
| three layer impact simulation for large cranioplasty using non-linear finite element model. | in this study, we conducted biomechanical study about implant material and behavior of large cranioplasty upon post-operative impact injury. previous studies utilized a surface model of the skull and large cranium patch (defect area is 46.7 cm2)[1,2,3,4]. it had single layer with thickness of adult skull as 7 cm in the parietal bone. after construction of the finite element model, the mesh and node data were analyzed for the static behavior of the patch. four-node and three-node quadrilateral sh ... | 2002 | 12085645 |
| a noncontact, nondestructive method for quantifying intratissue deformations and strains. | the function of soft connective tissues is frequently characterized by quantifying tissue strain (e.g., during joint motion). conventional techniques for quantifying tendon and ligament strain typically provide surface measures, using markers, stain lines or instrumentation that may influence the tissue. an alternative approach is to quantify intratendinous strain by applying texture correlation analysis to magnetic resonance (mr) images. this paper reports the accuracy and reproducibility of th ... | 2002 | 12002136 |
| up-regulation of vasopressin and angiotensin ii receptors in the thalamus and brainstem of inbred polydipsic mice. | vasopressin (avp), angiotensin ii (ang ii) and oxytocin (ot) receptors were mapped in the brain of inbred polydipsic mice of the str/n strain by quantitative in vitro autoradiography and receptor binding levels, compared with those found in control non-polydipsic mice of the icr strain. a remarkable difference was evidenced in the thalamic paraventricular nucleus where avp receptor binding was 7- to 10-fold higher in polydipsic mice than in control mice. another disparity was observed in the hyp ... | 2002 | 11867939 |
| cytological analysis of anastomoses and vegetative incompatibility reactions in helicobasidium monpa. | our examination of the cytological characteristics of the vegetative incompatibility reaction in a filamentous basidiomycete, helicobasidium monpa, by analyzing the fluorescence emitted by ethidium bromide and acridine orange stained nuclei is described. hyphal anastomoses between strains belonging to different mycelium compatibility groups (mcg) were observed with cell death in fused hyphae, whose nuclei were intensified by ethidium bromide. in contrast, the nuclei in a living cell were not int ... | 2002 | 11815862 |
| [quality of life stress in patients with larger tumors of the mouth. a descriptive study of psychosocial effects of illness and primary surgery therapy in 3 parts--1: quantity and quality of life]. | up to about 40 years ago, the therapy of large tumors of the oral cavity often resulted in severe disfigurement and dysfunctions. modern resection and reconstruction techniques now enable tumors of this type to be removed in such a way that virtually normal eating and speech functions are restored and traces of the extensive surgery are barely noticeable in many patients. after rehabilitation, most of these patients seem objectively to have a high quality of life, but it is less clear whether th ... | 2001 | 11793924 |
| relation of type a behavior pattern and job-related psychosocial factors to nonfatal myocardial infarction: a case-control study of japanese male workers and women. | to study the relation of type a behavior pattern and job-related psychosocial factors to the risk of myocardial infarction. | 2015 | 11573028 |
| cognitive-affective stress response: effects of individual stress propensity on physiological and psychological indicators of strain. | the purpose of this study was to define further the role of individual stress propensity in physiological arousal and subsequent subjective stress and strain by measuring stress-induced reactivity in a laboratory setting. individual predisposition to stress is conceptualized as a latent construct, cognitive-affective stress propensity, that is manifested as multiple trait indicators, e.g., negative affectivity, anger-irritability, and negative self-esteem. for 80 undergraduates experimental trea ... | 2001 | 11508018 |
| topological challenges to dna replication: conformations at the fork. | the unwinding of the parental dna duplex during replication causes a positive linking number difference, or superhelical strain, to build up around the elongating replication fork. the branching at the fork and this strain bring about different conformations from that of (-) supercoiled dna that is not being replicated. the replicating dna can form (+) precatenanes, in which the daughter dnas are intertwined, and (+) supercoils. topoisomerases have the essential role of relieving the superhelica ... | 2001 | 11459956 |