| [spontaneous bacterial peritonitis in a patient with decompensated alcoholic cirrhosis of the liver]. | spontaneous bacterial peritonitis (sbp) constitute a rare complication of cirrhosis of the liver with a high mortality rate. unspecific sings of decompensation like increasing elaboration of ascites or the development of hepatic encephalopathy are often prevailing. fever and peripheral blood leukocytosis as well as abdominal sings of peritonitis are not rarely completely missing. there is a strong suspicion of sbp with an ascitic polymorphonuclear count of greater than 500/mm3. determination of ... | 1992 | 1528085 |
| isolation of the fourth ventricle causing transtentorial herniation: neurosonographic findings in premature infants. | significant posthemorrhagic enlargement of the fourth ventricle occurs only in a small minority of patients. although entrapment or isolation of any ventricle can occur, the fourth ventricle is the most common site. this study was undertaken to better understand enlargement of the fourth ventricle after intraventricular hemorrhage and the neurosonographic features of isolation and transtentorial herniation. | 1992 | 1529848 |
| [bacteriological safety in enteral nutrition in intensive care units. comparison of 4 types of pumps]. | enteral nutrition may appear as a risk factor for infection in intensive care patients if bacterial growth is not prevented. the authors have tested in the microbiology laboratory, 4 types of pumps (3 cooling machines: sec nutridose/climadose, peters npr 3000, vial "alaska" and 1 flow regulator sherwood kangaroo 330) using food contaminated with a low inoculum of klebsiella pneumoniae. bacterial growth was investigated periodically in the food container and in the feeding tube during the testing ... | 1992 | 1532085 |
| enhanced localization of liposomes with prolonged blood circulation time in infected lung tissue. | in an experimental model of unilateral pneumonia caused by klebsiella pneumoniae in rats we investigated whether intravenous administration of liposomes with prolonged blood circulation time resulted in significant localization of liposomes in infected lung tissue. liposomes (100 nm) composed of hydrogenated phosphatidylinositol:hydrogenated phosphatidylcholine:cholesterol (molar ratio, 1:10:5) radiolabeled with gallium-67-deferoxamine showed relatively long blood circulation time. the degree of ... | 1992 | 1532911 |
| [bacteriology of neonatal septicemia in dakar]. | between february 1983 and february 1991, 471 blood cultures from newborns with neonatal infection, aged from 0 to 30 days, admitted to the pediatric hospital albert royer, dakar, were performed. in 141 (30.3 percent) cases, one bacterium was isolated. three major causative organisms were identified: klebsiella spp (28.6 percent), e. coli (19.5 percent) and s. aureus (17.4 percent). altogether, we isolated 99 (69.2 percent) enterobacteria, 7 (4.8 percent) other gram negative bacilli and 37 (25.8 ... | 1992 | 1533034 |
| [prevention of acute otitis media. amoxicillin versus glycoproteins from klebsiella pneumoniae. study in children under 5 years of age]. | several studies in the english language literature have shown that continuous antibiotic prophylaxis is more effective than a placebo in preventing recurrent otitis media. in this prospective, randomized trial the effectiveness of continuous amoxicillin therapy was compared with that of glycoproteins from klebsiella pneumoniae (gkp). the two treatments were administered during 3 months to children aged 1 to 5 years, who had at least 3 episodes of otitis media within the 3 months preceding their ... | 1992 | 1533455 |
| the prokaryotic enhancer binding protein ntrc has an atpase activity which is phosphorylation and dna dependent. | the prokaryotic activator protein ntrc binds to enhancer-like elements and activates transcription in response to nitrogen limitation by catalysing open complex formation by sigma 54 rna polymerase holoenzyme. formation of open complexes requires the phosphorylated form of ntrc and the reaction is atp dependent. we find that ntrc has an atpase activity which is activated by phosphorylation and is strongly stimulated by the presence of dna containing specific ntrc binding sites. | 1992 | 1534752 |
| siderophore production of klebsiella species isolated from different sources. | a total of 481 klebsiella pneumoniae and k. oxytoca strains isolated from different sources was examined for siderophore production. screening for siderophore secretion by chrome azurol s agar revealed that 475 strains (98.8%) produced siderophores. the isolates were further investigated for synthesis of enterochelin and aerobactin by means of specific bioassays. almost all klebsiella strains (99.4%) excreted enterochelin. aerobactin production, however, was rarely observed among k. pneumoniae ( ... | 1992 | 1535249 |
| dna sequence analysis of the lamb gene from klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin. | we have determined the sequence of the lamb gene from klebsiella pneumoniae. it encodes the precursor to the lamb protein, a 429 amino acid polypeptide with maltoporin function. comparison with the escherichia coli lamb protein reveals a high degree of homology, with 325 residues strictly identical. the n-terminal third of the protein is the most conserved part of the molecule (1 change in the signal sequence, and 13 changes up to residue 146 of the mature protein). differences between the two m ... | 1992 | 1535683 |
| controlled comparison of the bact/alert and bactec 660/730 nonradiometric blood culture systems. | in a collaborative study at three university hospitals, the recovery of microorganisms and the speed of detection of microbial growth by the bact/alert (organon teknika corporation, durham, n.c.) and bactec 660/730 (becton-dickinson diagnostic instrument systems, sparks, md.) nonradiometric blood culture systems were compared. a total of 5,918 comparisons were made between bact/alert aerobic and bactec nr 6a bottles and 5,992 comparisons were made between bact/alert anaerobic and bactec nr 7a bo ... | 1992 | 1537900 |
| metabolism of benzonitrile and butyronitrile by klebsiella pneumoniae. | a strain of klebsiella pneumoniae that used aliphatic nitriles as the sole source of nitrogen was adapted to benzonitrile as the sole source of carbon and nitrogen. gas chromatographic and mass spectral analyses of culture filtrates indicated that k. pneumoniae metabolized 8.4 mm benzonitrile to 4.0 mm benzoic acid and 2.7 mm ammonia. in addition, butyronitrile was metabolized to butyramide and ammonia. the isolate also degraded mixtures of benzonitrile and aliphatic nitriles. cell extracts cont ... | 1992 | 1539979 |
| immune complexes in ankylosing spondylitis. | immune complexes have been reported in ankylosing spondylitis (as) and may implicate infectious agents. serum samples from 49 patients with as were assayed for immune complexes by polyethylene glycol precipitation, followed by radial immunodiffusion and pepsinogen binding immunoassay. both methods showed increases in iga containing immune complexes, which correlated with serum iga and with iga rheumatoid factor concentrations, but did not show increases in other immune complex components. increa ... | 1992 | 1540045 |
| [evaluation of the so-called basic cephalosporins using the serum bactericidal test]. | the serum bactericidal activity (sba) was studied one hour and four hours after intravenous administration of 1 g and 2 g cefotiam, 1.5 g cefuroxime and 2 g cefazolin to six volunteers. the 136 clinical isolates tested included staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, proteus mirabilis and haemophilus influenzae. one hour after administration no significant differences in the activity against staphylococci were noted in the antibiotics tested. f ... | 1992 | 1542283 |
| the sodium ion pumping oxaloacetate decarboxylase of klebsiella pneumoniae. metal ion content, inhibitors and proteolytic degradation studies. | oxaloacetate decarboxylase of klebsiella pneumoniae was shown to contain between 0.6 and 1.0 mol zinc per mol enzyme in different preparations. the decarboxylase activity was completely abolished after 15 min incubation with 1 mm hg(no3)2 in phosphate buffer, while the activity decreased only 20% if the incubation was performed in mes/tris buffer. treatment of the isolated subunits with hg(no3)2 indicated that the binding site for hg2+ ions is on the alpha subunit. other inhibitors of the decarb ... | 1992 | 1547890 |
| iga antibody response to klebsiella in ankylosing spondylitis measured by immunoblotting. | iga antibodies to klebsiella pneumoniae var oxytoca and proteus mirabilis were measured in 66 patients with ankylosing spondylitis (as) and 31 with rheumatoid arthritis (ra) and in 51 healthy control subjects, using an immunoblotting technique. the number of antigenic bands to klebsiella on nitrocellulose membrane was higher in 28 patients with active as than in 38 patients with inactive as, 31 patients with ra, and 51 healthy control subjects; comparatively smaller increases were found against ... | 1992 | 1550409 |
| cloning and nucleotide sequence of a negative regulator gene for klebsiella aerogenes arylsulfatase synthesis and identification of the gene as fola. | a negative regulator gene for synthesis of arylsulfatase in klebsiella aerogenes was cloned. deletion analysis showed that the regulator gene was located within a 1.6-kb cloned segment. transfer of the plasmid, which contains the cloned fragment, into constitutive atsr mutant strains of k. aerogenes resulted in complementation of atsr; the synthesis of arylsulfatase was repressed in the presence of inorganic sulfate or cysteine, and this repression was relieved, in each case, by the addition of ... | 1992 | 1551851 |
| role of lipid modification on a starch-debranching enzyme, klebsiella pullulanase: comparison of properties of lipid-modified and unmodified pullulanases. | klebsiella pullulanase is a lipoprotein synthesized as a precursor with a signal peptide, which is processed by lipoprotein signal peptidase. to clarify the role of lipid modification of pullulanase, we purified lipid-modified wild-type and the unmodified (mutant) pullulanases and compared their properties. the km and vmax values of both pullulanases for pullulan were the same. the optimal ph and temperature, the stabilities over ph and temperature ranges, the specificity of substrates, and the ... | 1992 | 1552852 |
| protection by a polyvalent vaccine against challenge infection and pyelonephritis. | the protective effect of immunization with a polyvalent vaccine (solcourovac) was studied in the mouse and the rat. the i.m. immunization increased the resistance of mice to challenge infection with all homologous strains of bacteria. the ld50 values for e. coli, proteus mirabilis and streptococcus were 3.5-4.5 times and that of klebsiella as much as 600 times that in nonimmunized mice. protection against challenge with heterologous e. coli was also achieved and persisted for about 20 weeks. imm ... | 1992 | 1553795 |
| molecular mimicry in the pathogenesis of spondyloarthropathies. a critical appraisal of cross-reactivity between microbial antigens and hla-b27. | we describe an amino acid homology between a virulence plasmid encoded outer membrane protein of yersinia, yada (previously called yop1) and hla-b27. this tetrapeptide is also included in the hexapeptide, earlier found to be identical between klebsiella nitrogenase and hla-b27. the synthetic peptide based on the hla-b27 homologous portion of the yada does not stimulate lymphocytes obtained from hla-b27+ patients with yersinia-triggered reactive arthritis or from controls. one-third of the yersin ... | 1992 | 1555037 |
| cloning and expression of an arabidopsis nitrilase which can convert indole-3-acetonitrile to the plant hormone, indole-3-acetic acid. | from an arabidopsis thaliana cdna expression library, a cdna clone was isolated, characterized and sequenced which, at the amino acid level, resembled the klebsiella ozaenae bromoxynil nitrilase encoded by the bxn gene. the cdna contained a long open reading frame, starting from two possible neighbouring atg codons and capable of encoding 340 or 346 amino acids with calculated molecular masses of 37526 da or 38176 da, respectively. the sequence similarity between the deduced polypeptides from th ... | 1992 | 1555601 |
| a monoamine-regulated klebsiella aerogenes operon containing the monoamine oxidase structural gene (maoa) and the maoc gene. | the klebsiella aerogenes gene maoa, which is involved in the synthesis of monoamine oxidase, was induced by tyramine and the related compounds, subjected to catabolite and ammonium ion repression, and cloned. the nucleotide sequence of the region involved in monoamine oxidase synthesis was determined. two open reading frames, the maoa gene and a hitherto unknown gene (maoc), were found. these are located between a potential promoter sequence and a transcriptional terminator sequence. a region of ... | 1992 | 1556068 |
| quantitative separation of bacteria in saline solution using lanthanide er(iii) and a magnetic field. | a trivalent lanthanide ion, erbium (er3+), has been used in combination with a magnetic separation technique to isolate seven bacterial species from suspensions in 0.9% saline. erbium has an exceptionally high atomic magnetic moment of 9.3 bohr magnetons, and following addition as ercl3 (final concentration 5 mm) to bacterial suspensions, it imparts the magnetic moment to the bacterial cells by ionic binding to the cell surface. strains of escherichia coli, klebsiella pneumoniae, proteus mirabil ... | 1992 | 1556557 |
| [multicausal infectious respiratory tract disease of young fattening turkeys]. | the outbreak of the disease occurred in a large multiple-age farm with about 50,000 meat turkeys, where groups of 6-8000 one-day-old birds were stalled up every 14 days. all the turkey poults housed were affected mostly in the 1.-3. week of the life. the respiratory disease spread rapidly within the flocks and were characterised clinically by inclination of huddle, ruffled feathers, anorexia, stunted growth, swelling of the infraorbital sinus and nasal discharge. the clinical apparent disease la ... | 1992 | 1559465 |
| klebsiella capsular type k7 in relation to toxicity, susceptibility to phagocytosis and resistance to serum. | klebsiella strains possessing capsule type k7 are found predominantly in respiratory secretions. to investigate the importance of this k antigen in virulence, 13 k7 strains were compared with k2 capsulate isolates which are generally regarded as highly virulent. the toxicity of the strains was determined in a mouse peritonitis model. generally, k7 isolates were significantly less toxic for mice than k2 strains. in the absence of serum, neither capsule type showed much stimulation of leucocytes, ... | 1992 | 1560447 |
| short and long courses of ofloxacin therapy of klebsiella pneumoniae sepsis following irradiation. | exposure to whole-body irradiation is associated with fatal gram-negative sepsis. the optimal length of therapy of such infection is not established. the effect of short and long courses of oral therapy with the quinolone ofloxacin for orally acquired klebsiella pneumoniae infection was tested in b6d2f1 mice exposed to 8.0 gy of bilateral radiation from 60co. a dose of 10(8) organisms was given orally 4 days after irradiation, and therapy was started 1 day later. cultures of the ileum 7 days aft ... | 1992 | 1561319 |
| ankylosing spondylitis is caused by klebsiella. evidence from immunogenetic, microbiologic, and serologic studies. | ankylosing spondylitis is a form of reactive arthritis following klebsiella infection, usually occurring in an hla-b27-positive individual. this conclusion is based on evidence obtained from several disciplines: immunogenetic studies show that there is molecular mimicry between hla-b27 and klebsiella; increased isolation of fecal klebsiella has been reported in both europe and north america; and finally, antibodies to klebsiella have been demonstrated in ankylosing spondylitis patients in englan ... | 1992 | 1561397 |
| ankylosing spondylitis is not caused by klebsiella. | the suggested relationship of klebsiella species to the pathogenesis of ankylosing spondylitis reflects evidence that there was an increase in fecal klebsiella carriage in patients with active as when compared to controls, that b27-positive lymphocytes from as patients could be distinguished from normal b27-positive lymphocytes by an antiserum, and that a nitrogenase enzyme found in some species of klebsiella had a sequence of six amino acids identical to a sequence seen in b*2705. it is the aut ... | 1992 | 1561412 |
| ga-67 uptake unsuppressed by leukopenia and intense antibiotic therapy. | the authors describe a patient with myelofibrosis who showed intense ga-67 uptake in spite of being severely leukopenic and receiving large amounts of antibiotics. they conclude that false-negative results associated with leukopenia or intensive antibiotic treatment may not always be correct. | 1992 | 1563190 |
| a case of malignant external otitis involving klebsiella oxytoca. | | 1992 | 1563390 |
| [outbreak of a nosocomial infection of shv2-beta-lactamase-containing klebsiella pneumonia strains in an operative intensive care unit]. | resistant strains of klebsiella pneumoniae were found in increasing frequency as a cause of nosocomial infection in an intensive care unit between july and october 1990. the isolated strains had an almost identical biochemical profile, showed a similar pattern of antibiotic resistance, and produced type shv2-broad-spectrum betalactamase. thus, it was assumed that the isolates were copies of identical strains, causing an outbreak of nosocomial infections. the bacteria were resistant to third-gene ... | 1992 | 1563756 |
| monoclonal antibody against klebsiella capsular polysaccharide reduces severity and hematogenic spread of experimental klebsiella pneumoniae pneumonia. | klebsiella pneumoniae is an important nosocomial pathogen causing severe pulmonary infections. the majority of clinical klebsiella isolates produce a high-molecular-weight capsular polysaccharide (cps) which is one of the dominant virulence factors. in the present study, we examined the potency of a murine immunoglobulin m monoclonal antibody (mab) with specificity to klebsiella type 2 cps to protect rats against experimental klebsiella pneumonia. the mab did not prevent the invasion of virulent ... | 1992 | 1563764 |
| bacterial quantification--a necessary complement for the comprehension of middle ear inflammations. | quantification of bacteria in various types of middle ear effusion (mee) obtained during current acute otitis media (aom), otitis media with effusion (ome) and chronic suppurative otitis media (com) was performed. the bacteria were stained with acridine orange and their number per ml effusion evaluated under the fluorescence microscope according to a method described in detail elsewhere. during aom, 53% of the mee samples were culture-positive and contained 10(6)-10(8) bacteria per ml (median va ... | 1992 | 1563927 |
| [spontaneous bacterial peritonitis]. | we describe five patients with spontaneous bacterial peritonitis. the condition is reported more frequently than before and survival has improved. important clinical features are increasing ascites and unexpected derangement of liver function. possible predisposing factors, as well as diagnostic and therapeutic measures, are discussed. we emphasize the significance of ascitic polymorph nuclear cell count and bedside inoculation of ascites on blood culture medium, and stress the importance of pro ... | 1992 | 1566247 |
| effectiveness of cefetamet pivoxil in the treatment of pyelonephritis in children. | cefetamet pivoxil was investigated in an open, randomized comparative study involving a total of 37 children with acute pyelonephritis, whose ages ranged from 2 to 14 years. the patients received either 10 mg/kg (n = 18) or 20 mg/kg (n = 8) cefetamet pivoxil twice daily, or 30-50 mg/kg amoxycillin/clavulanic acid three times daily (n = 11) for a period of 7-10 days. escherichia coli was the main causative agent isolated in 28 (75.7%) of the patients; other pathogens included proteus mirabilis (t ... | 1992 | 1568523 |
| pneumothorax and perforated peptic ulcer without pneumoperitoneum. | | 1992 | 1568552 |
| the prevalence and prognostic significance of spontaneous bacterial peritonitis in severe acute hepatitis with ascites. | the prevalence and prognostic significance of spontaneous bacterial peritonitis were prospectively studied in a series of 82 acute hepatitis patients decompensated with ascites. the in-hospital prevalence of spontaneous bacterial peritonitis was 31.7% (26 of 82 patients). twenty cases were culture positive, including one with multiple isolates, and six cases were culture negative. e. coli and klebsiella pneumoniae were the most common pathogens, accounting for 71.4% (15 of 21) of the total isola ... | 1992 | 1568720 |
| isolation and characterization of kika, a region on incn group plasmids that determines killing of klebsiella oxytoca. | transfer of the incn group plasmid pcu1 from escherichia coli to klebsiella oxytoca by conjugation kills a large proportion (90 to 95%) of the recipients of plasmid dna, whereas transfer to e. coli or even to the closely related enterobacter aerogenes does not. two regions, kika and kikb, have been identified on pcu1 that contribute to the kik (killing in klebsiellas) phenotype. we have localized the kika region to 500 bp by deletion analysis and show by dna-dna hybridization that kika is highly ... | 1992 | 1569033 |
| urinary tract infections in patients with diabetes mellitus. | we have endeavoured to determine whether there is any difference in the bacteriological pattern of uti and the antibiotic sensitivity patterns of the pathogens concerned between diabetic and non-diabetic patients. over a period of 1 year, a total of 287 diabetic patients (221 females and 66 males) with community-acquired and nosocomial urinary tract infections were studied. there were 265 patients (228 females and 37 males) without any predisposition to urinary tract infections (uti) and who ser ... | 1992 | 1569307 |
| dietary fish-oil supplementation in experimental gram-negative infection and in cerebral malaria in mice. | dietary fish-oil supplementation interferes with eicosanoid production and appears to decrease production of interleukin-1 (il-1) and tumor necrosis factor (tnf). the effect of fish oil was investigated in an intramuscular klebsiella pneumoniae infection in swiss mice and in cerebral malaria induced by plasmodium berghei in c57b1/6 mice. after a low inoculum of k. pneumoniae, 90% of fish oil-fed mice survived; survival in control mice fed equal amounts of corn or palm oil or normal chow was 30%, ... | 1992 | 1569340 |
| electrode and bacterial survival with iontophoresis in synthetic urine. | urinary catheters, especially in patients with long-term catheter requirements, frequently are a source of infection. iontophoresis has been proposed as a method to decrease or eliminate such infections. several types of material were examined for their potential use as electrodes in an iontophoretic catheter system. silver, copper and nickel electrodes did kill microorganisms but did not show longevity. carbon and gold electrodes showed longevity and killing of microorganisms. gold proved to be ... | 1992 | 1569674 |
| [identification of a new penicillinase in a klebsiella pneumoniae strain of which a mutant also produces an esterase hydrolyzing cephalothin and cefotaxime]. | klebsiella pneumoniae strain l 164 produces a penicillinase whose isoelectric point is 8.1, an unusual figure for this bacterial species. this strain exhibits resistance to conventional penicillins and a synergistic effect is seen with clavulanic acid. in contrast, susceptibility to cephalosporins is marked, as shown by the low minimum inhibitory concentrations (mics). this phenotype is characteristic of strains with no acquired resistance. a first mutant with mics for cephalothin and cefotaxime ... | 1992 | 1570180 |
| [evaluation of the atb 32 e system for automated identification of enterobacteriaceae]. | a new automated system ensuring identification of enterobacteriaceae within four hours was evaluated using 269 routine isolates, comparatively with the techniques routinely used in the laboratory. the atb 32 e system correctly identified 96% (258/270) of strains and yielded incorrect results for 4% (11/269) of strains. atb 32 e is a reliable system which is easy to use in everyday laboratory work. | 1992 | 1570187 |
| single dose cephalosporin prophylaxis in high-risk patients undergoing surgical treatment of the biliary tract. | during june 1985 through october 1986, 292 patients considered to be at high risk for having postoperative complications develop underwent cholecystectomy and were evaluated in a multicenter, randomized, prospective, double-blind study. risk factors included age greater than 70 years, acute cholecystitis within the previous six months, obstructive jaundice, obesity and diabetes mellitus. one gram of cefamandole was administered intravenously to 144 patients and 148 patients received 1 gram of ce ... | 1992 | 1570609 |
| [resistance of aminoglycosides to bacteria in the klebsiella, enterobacter and serratia groups]. | | 1992 | 1570650 |
| a comparison of antimicrobial activity of ofloxacin, l-ofloxacin, and other oral agents for respiratory pathogens. | the attainable inhibitory ratios (ar) for oral antibiotics were calculated by using literature reports of concentrations attained in respiratory secretions for amoxicillin-clavulanic acid (amx/ca), ofloxacin (ofl), l-ofloxacin (l-ofl), cefuroxime (cefu), ciprofloxacin (cip), and enoxacin (eno), and using microdilution minimum inhibitory concentration data of these antimicrobials against the common bacterial respiratory pathogens. ar of each antibiotic against the pathogens was expressed as multi ... | 1992 | 1572139 |
| an enzyme with type iv prepilin peptidase activity is required to process components of the general extracellular protein secretion pathway of klebsiella oxytoca. | the last gene (pulo) of the pulc-o pullulanase secretion gene operon of klebsiella oxytoca codes for a protein that is 52% identical to the product of the pild/xcpa gene required for extracellular protein secretion and type iv pilus biogenesis in pseudomonas aeruginosa. the pild/xcpa protein is known to remove the first six amino acids of the signal sequence of the type iv pilin precursor by cleaving after the glycine residue in the conserved sequence gf(m)xxxe (where x represents hydrophobic am ... | 1992 | 1574004 |
| [typing by isoelectric focusing of beta-lactamase enzymes in klebsiella and enterobacter strains resistant to the new beta-lactam antibiotics]. | resistance to new generation beta-lactam antibiotics in gram-negative bacteria is increasing worldwide. this resistance is due to ebs enzymes in klebsiella spp., and type-i chromosomal enzymes in enterobacter spp., citrobacter, p. aeruginosa, providencia, m. morganii and s. marcescens. in this study, the types of beta-lactamases in 16 klebsiella spp. and 15 enterobacter spp. which are resistant to newer beta-lactam antibiotics was investigated by isoelectric focusing. the results of the study sh ... | 1992 | 1574017 |
| an outbreak of klebsiella oxytoca septicemias associated with the use of invasive blood pressure monitoring equipment. | seven cases of septicemia with piperacillin-resistant klebsiella oxytoca (prko) occurred at 2-monthly intervals in a thoracic surgery intensive care unit. all prko isolates were serotyped, and phenotyped with a biochemical typing system. only one patient in the unit was found to be colonized in stool or respiratory tract with prko, and this strain was different from the septicemia strains in phenotype though not in serotype. environmental cultures, from humidifiers, oxygenators, pressure transdu ... | 1992 | 1574979 |
| [aortoenteric fistula. a severe disorder with difficult diagnosis]. | | 1992 | 1576197 |
| influence of three-day antimicrobial therapy and lactobacillus vaginal suppositories on recurrence of urinary tract infections. | forty-one adult women with acute lower urinary tract infections (uti) were randomly treated for three days with norfloxacin or trimethoprim/sulfamethoxazole (tmp/smx). infection was eradicated in 100% of norfloxacin-treated patients and in 95% of tmp/smx-treated patients. uti recurred in 29% of patients treated with norfloxacin and in 41% of those treated with tmp/smx. post-therapy vaginal administration of lactobacillus suppositories resulted in a recurrence rate of uti of only 21%, while in pa ... | 1992 | 1576619 |
| efficacy of two comparative antibiotic regimens in the treatment of serious intra-abdominal infections: results of a multicenter study. | a multicenter, open-label randomized trial was conducted to evaluate the efficacy and tolerability of monotherapy with imipenem-cilastatin (i-c) compared with combination therapy with clindamycin and an aminoglycoside (c+a) for treatment of 117 patients with serious intra-abdominal infections. fifty-three patients (45%) received i-c and 64 patients (55%) received c+a. the overall clinical success rate was 96.2% for the i-c patients and 92.2% for the c+a patients. clinical failure rates were 3.8% ... | 1992 | 1576632 |
| nucleotide sequence and functional properties of a sodium-dependent citrate transport system from klebsiella pneumoniae. | the gene of the sodium-dependent citrate transport system from klebsiella pneumoniae (cits) is located on plasmid pes3 (schwarz, e., and oesterhelt, d. (1985) embo j. 4, 1599-1603) and encodes a 446-amino acid protein. transport of citrate via this citrate transport protein (cits) is dependent on the presence of sodium ions and is inhibited by magnesium ions. the delta ph (ph gradient across the membrane) is the major driving force for uptake. it is postulated that, in analogy with the proton-de ... | 1992 | 1577734 |
| the dependence on iron availability of allocation of iron to nitrogenase components in klebsiella pneumoniae and escherichia coli. | nitrogenase contains approximately 38 iron ions/complete unit. therefore, we sought to identify steps and genes involved in nitrogenase production that are responsive to iron availability. we have characterized nitrogenase production in klebsiella pneumoniae grown in a range of different iron concentrations. we find significant accumulation (50-75%) and normal synthesis rates of the structural polypeptides, even under conditions in which the observed nitrogenase activities are only 14-28% of tho ... | 1992 | 1577767 |
| multicenter open-label study of parenteral ofloxacin in treatment of pyelonephritis in adults. | the efficacy and safety of parenteral ofloxacin were evaluated in an open, multicenter study of hospitalized patients with pyelonephritis. the patients received ofloxacin 400 mg iv as an initial dose followed by ofloxacin 200 mg iv b.i.d. for a minimum of three days. the patients could then continue ofloxacin orally 200 mg b.i.d. for a total of seven to fourteen days. the most common pathogens isolated were escherichia coli, enterobacter cloacae, and klebsiella pneumoniae. microbiologic eradicat ... | 1992 | 1580038 |
| identification of klebsiella pneumoniae by dna hybridization and fatty acid analysis. | on the basis of the idea that dna sequences encoding cell surface-exposed regions of outer membrane proteins are genus or species specific, two oligonucleotide probes which were based on the phoe protein of klebsiella pneumoniae were evaluated. in slot blot hybridizations and in polymerase chain reactions, no cross-hybridizations were observed with non-klebsiella strains. when the probes were tested on 75 different k-antigen reference klebsiella strains, 16 strains were not recognized although t ... | 1992 | 1581186 |
| effect of the method of preparing monochloramine upon inactivation of ms2 coliphage, escherichia coli, and klebsiella pneumoniae. | monochloramine prepared in situ by first adding chlorine to a suspension of microorganisms, followed by subsequent addition of ammonia, inactivated the ms2 coliphage more rapidly than did exposure of phage to monochloramine prepared either by adding chlorine to ammonia or by adding chlorine and ammonia simultaneously. the rapid viral inactivation was apparently due to the exposure of ms2 to free chlorine before the addition of ammonia. the average 99% ct value of ms2 when exposed to free chlorin ... | 1992 | 1581862 |
| further observations on the serological response to experimental salmonella typhimurium in chickens measured by elisa. | an indirect elisa developed for the serological detection of salmonella typhimurium in chickens using lipopolysaccharide as detecting antigen has been evaluated further in experimental infections. following oral infection of 24-week-old laying hens with an invasive strain of s. typhimurium, high titres of specific circulating igg were induced which were maintained for 20 weeks. similar igg titres were found in egg yolk. when 4-day-old chickens were infected high antibody titres persisted for 45 ... | 1992 | 1582466 |
| salicylate or bismuth salts enhance opsonophagocytosis of klebsiella pneumoniae. | after treatment of encapsulated klebsiella pneumoniae with salicylate or bismuth compounds, phagocytic uptake by human peripheral white blood cells or rat alveolar macrophages was assessed. without salicylate pretreatment of bacteria, a 30-60% net increase in viable bacteria resulted in phagocytic assays after a 1 hour incubation. with salicylate pretreatment, dose-related decreases in bacterial counts were seen, achieving a maximal reduction of 60% with 240 microm salicylate pretreatment. bacte ... | 1992 | 1582686 |
| [an evaluation of the biochemical typing of klebsiella cultures]. | the paper deals with the results of analysis of 219 strains of klebsiella using 12 tests--fermentation of adonite, asparaginic acid, sodium citrate, dulcite, d-tartrate, glutamic acid, inosite, l-proline, sodium malonate; reactions with methyl red, foges-proscauer, with 5-asa. a scheme for determining fermentovars of klebsiella is suggested which includes the tests--fermentation of adonite, dulcite, d-tartrate, glutamic acid; color reaction with 5-asa. the groups of klebsiella different in origi ... | 1992 | 1584083 |
| [the microbiological and pathomorphological characteristics of klebsiella infection]. | biological properties of 350 strains of klebsiella pneumoniae isolated in newborns during the outbreak of intrahospital infection have been studied. experimental infection with isolated strains of a similar plasmid profile is simulated, interrelation between the presence of plasmids and ability of the strain to induce generalized klebsiella infection is shown. pathological processes in the newborns with generalized infection and in animals with the reproduced experimental klebsiella infection ar ... | 1992 | 1584089 |
| endogenous klebsiella pneumoniae endophthalmitis in diabetic patients. | we describe 12 patients with endogenous endophthalmitis caused by klebsiella pneumoniae seen between 1983 and 1988. three patients had bilateral involvement. eleven patients had diabetes mellitus, either newly diagnosed or poorly controlled. in six cases the infection was associated with a liver abscess. in all eyes the outcome was light perception or worse; nine eyes had no light perception. six eyes were enucleated or eviscerated. | 1992 | 1586886 |
| mechanisms of klebsiella pneumoniae resistance to complement-mediated killing. | the different mechanisms of klebsiella pneumoniae resistance to complement-mediated killing were investigated by using different strains and isogenic mutants previously characterized for their surface components. we found that strains from serotypes whose k antigen masks the lipopolysaccharide (lps) molecules (such as serotypes k1, k10, and k16) fail to activate complement, while strains with smooth lps exposed at the cell surface (with or without k antigen) activate complement but are resistant ... | 1992 | 1587619 |
| bacteriology of wound infection: evaluation by surface swab and quantitative full thickness wound biopsy culture. | a total of 171 cases of wounds of various aetiology were examined and screened bacteriologically for evidence of infection by surface swab culture and quantitative full thickness wound biopsy culture techniques. staphylococcus pyogenes was the most frequently isolated (39.9%) single organism. other organisms being escherichia coli (26.1%), pseudomonas aeruginosa (15.4%), klebsiella species (5.8%), streptococcus pyogenes (4.9%), proteus species (4.8%) and coliform organism (3.1%). collectively th ... | 1992 | 1588115 |
| ticarcillin and ticarcillin-clavulanic acid susceptibility tests: error rates for disk tests with consecutively isolated members of the family enterobacteriaceae. | a five-laboratory coordinated study was undertaken to determine whether ticarcillin and ticarcillin-clavulanic acid disk susceptibility tests could accurately detect resistance among enteric bacilli. each facility performed disk tests and broth microdilution susceptibility tests with reagents distributed from a common source, and appropriate controls were included in order to ensure methodologic uniformity. each institution tested 500 consecutively isolated enteric bacilli against ticarcillin an ... | 1992 | 1590679 |
| synergistic effects of romurtide and cefmenoxime against experimental klebsiella pneumonia in mice. | we investigated the synergistic effects of romurtide (mdp-lys [l18]) and cefmenoxime (cmx) in the treatment of experimental klebsiella pneumonia in mice. mice were infected with 1 x 10(4) cfu of klebsiella pneumoniae by inhalation of aerosol bacterial suspension. about 90% of untreated animals died within a week; however, the mortality rate of animals treated with cmx alone at a dose of 40 mg/kg/day was 60% at 7 days after the infection. when one or two doses of l18 were administered before or a ... | 1992 | 1590684 |
| effect of protein binding in serum on therapeutic efficacy of cephem antibiotics. | the effect of protein binding in serum of eight cephem antibiotics (ceftazidime, ceftizoxime, cefotiam, cefmetazole, cefpiramide, cefazolin, cefuzonam, ceftriaxone) on their therapeutic efficacies was examined in mice with experimentally induced intraperitoneal infections or pneumonia. the relationship among therapeutic activity, in vitro antibacterial activity, total or free (unbound) levels in serum, and homogenized whole lung levels was investigated. in the intraperitoneal infection caused by ... | 1992 | 1590685 |
| distribution of beta lactamases in enterobacteriaceae: indoor versus outdoor strains. | the distribution of beta-lactamases of indoor and outdoor origin was studied over a 9-month period. we consecutively selected 37 indoor and 48 outdoor strains of the following genera of the enterobacteriaceae family: escherichia (species coli), enterobacter, proteus, and klebsiella. all isolates were resistant to amoxicillin and/or cephalothin and/or cefamandole. all strains showed beta-lactamase activity. we characterized the enzymes by an isoelectric focusing method and by a disc diffusion tes ... | 1992 | 1591949 |
| characterization of antibody responses of local lymph nodes to antigen given under the oral submucosa. | we studied the function of submandibular lymph nodes (mln) in the oral mucosa immune system as compared with that of inguinal lymph nodes (iln) in the cutaneous one. primary igm, igg and iga antibody responses in mln to sheep red blood cells (srbc) as a model antigen given submucosally occurred more extensively than those in iln to the antigen injected subcutaneously. particularly, definite iga synthesis was seen in mln but not in iln. this iga synthesis was shown to be originated locally in ora ... | 1992 | 1592428 |
| clinical and bacteriological study of normal and inflamed neonatal conjunctivae. | maternal vaginal and neonatal conjunctival flora were prospectively studied in a 117 mother baby pairs. the commonest isolates from both vaginal and conjunctival flora were e. coli, staphylococcus aureus and klebsiella species. in 85% of mother-baby dyads, isolates from vagina and conjunctiva were similar. the commonest bacterial isolates in neonates with conjunctivitis were staphylococcus aureus (37.4%), e. coli (27.9%) and klebsiella species (19.3%). maternal coitus, infections, rupture of mem ... | 1992 | 1592495 |
| ru 29 246, the active compound of the cephalosporin-prodrug-ester hr 916. i. antibacterial activity in vitro. | the aminothiazolyl-cephalosporin ru 29 246 is the active metabolite of the prodrug-pivaloyl-oxyethyl-ester hr 916. ru 29 246 in vitro activity includes a wide range of clinically relevant bacterial pathogens. against methicillin-sensitive staphylococci ru 29 246 (mic90 of 0.25 approximately 2 micrograms/ml) was clearly more active than cefaclor, cefuroxime, cefpodoxime, cefixime and ceftibuten, but slightly less active than cefdinir. ru 29 246 inhibited hemolytic streptococci of the serogroups a ... | 1992 | 1592683 |
| the frequency of extended-spectrum beta-lactamases in isolates of klebsiella pneumoniae. | | 1992 | 1592702 |
| anaerobic 2-ketogluconate metabolism of klebsiella pneumoniae nctc 418 grown in chemostat culture: involvement of the pentose phosphate pathway. | under anaerobic 2-ketogluconate-limited growth conditions (d = 0.1 h-1), klebsiella pneumoniae nctc 418 was found to convert this carbon source to biomass, acetate, formate, co2, ethanol and succinate. the observed fermentation pattern is in agreement with the simultaneous functioning of the pentose phosphate pathway and the entner-doudoroff pathway in 2-ketogluconate catabolism. when cultured at ph 8.0 apparent yatp values were lower than those found at culture ph 6.5. this difference can be ex ... | 1992 | 1593257 |
| central domain of the positive control protein nifa and its role in transcriptional activation. | the positive control protein nifa of klebsiella pneumoniae activates transcription by rna polymerase containing sigma 54 by catalysing open promoter complex formation. we show that the integrity of the putative atp-binding pocket in the central domain of nifa is necessary for the positive control function of nifa, but is not required for dna-binding or recognition of nifa by nifl. the inactive mutant nifa proteins are trans dominant to wild-type nifa and are unable to catalyse formation of open ... | 1992 | 1593620 |
| influence of pefloxacin on microbial colonization resistance in healthy volunteers. | the influence of pefloxacin, 400 mg twice daily for ten days, on microbial colonization resistance was investigated in six healthy volunteers. in three volunteers impairment of colonization resistance was indicated by a significant increase in the faecal concentration of yeasts. in two of them, impairment of colonization resistance was confirmed by facilitation of colonization by a challenge strain of klebsiella pneumoniae in the early post-treatment period. it is concluded that pefloxacin impai ... | 1992 | 1597205 |
| etiology of febrile episodes in children with acute lymphocytic leukaemia. | in 53 children (aged 5 months to 11 yr) with acute lymphoblastic leukemia, 68 febrile episodes were investigated for determining the etiology. microbial organisms were isolated in 33 episodes. bacteraemia was seen in 24 patients and in three of them clostridium species were isolated. escherichia coli was the commonest isolate and was seen in 11 (18.6%) febrile episodes. other common organisms isolated were staphylococcus aureus in nine (15.2%), and klebsiella pneumoniae and coagulase negative st ... | 1992 | 1597325 |
| outcome of very low birthweight neonates in a developing country: experience from a large malaysian maternity hospital. | between january 1989 to april 1990 (16 months), a prospective observational study was carried out on 329 consecutive very low birthweight (vlbw) less than or equal to 1500 grams) malaysian neonates born in the maternity hospital, kuala lumpur before their first discharge from the hospital. the objectives of the study were to determine the common causes of early morbidity and mortality of this group of malaysian neonates. the study shows that the incidence of malaysian vlbw neonates was 9.9 per 1 ... | 1992 | 1598605 |
| conversion of xylan to ethanol by ethanologenic strains of escherichia coli and klebsiella oxytoca. | a two-stage process was evaluated for the fermentation of polymeric feedstocks to ethanol by a single, genetically engineered microorganism. the truncated xylanase gene (xynz) from the thermophilic bacterium clostridium thermocellum was fused with the n terminus of lacz to eliminate secretory signals. this hybrid gene was expressed at high levels in ethanologenic strains of escherichia coli ko11 and klebsiella oxytoca m5a1(ploi555). large amounts of xylanase (25 to 93 mu/mg of cell protein) accu ... | 1992 | 1599236 |
| scintigraphy with j001x, a klebsiella membrane glycolipid, for the early diagnosis of chronic berylliosis: results from an experimental model. | a glycolipid (j001x) isolated from the membrane proteoglycans of a non-pathogenic strain of klebsiella pneumoniae was developed to bind selectively to macrophages. a scintigraphic technique could thus be developed and applied to an experimental model of lung berylliosis. six baboons were injected intratracheally with a beryllium metal suspension. three to 24 months later, they were submitted to both an anatomical and a functional respiratory evaluation. two baboons were explored at the early sta ... | 1992 | 1599873 |
| identification of the bactericidal domain of lactoferrin. | we report the existence of a previously unknown antimicrobial domain near the n-terminus of lactoferrin in a region distinct from its iron-binding sites. a single active peptide representing this domain was isolated following gastric pepsin cleavage of human lactoferrin, and bovine lactoferrin, and sequenced by automated edman degradation. the antimicrobial sequence was found to consist mainly of a loop of 18 amino acid residues formed by a disulfide bond between cysteine residues 20 and 37 of h ... | 1992 | 1599934 |
| comparison of clinical response to cefpirome treatment and minimum inhibitory concentration of causative isolates. microbiological and clinical study groups. | three hundred and forty-five clinical isolates from patients treated with cefpirome were studied using an mic methodology to develop tentative breakpoints for cefpirome, and to correlate clinical success with in-vitro susceptibility. no relationship between elimination, persistence and mic of potential pathogens was found. there was, however, a close relationship between clinical cure and improvement and eradication of causative organisms. based on the data, tentative breakpoints of less than 4 ... | 1992 | 1601762 |
| dna supercoiling response of the sigma 54-dependent klebsiella pneumoniae nifl promoter in vitro. | transcription from the sigma 54-dependent klebsiella pneumoniae nifl and glnap2 promoters is activated by the general nitrogen regulatory protein ntrc. unlike the glnap2 promoter, which is relatively insensitive to changes in dna supercoiling, transcription from nifl in vitro in a chloride-based buffer is supercoiling-dependent at physiological salt concentrations. the replacement of chloride with an acetate-based buffer decreases the stringency of the nifl supercoiling response, but open comple ... | 1992 | 1602472 |
| microflora of the pouch of the koala (phascolarctos cinereus). | microflora of the pouch epithelium of 17 female koalas (phascolarctos cinereus) were examined in relation to their current reproductive status and recent reproductive history. no microbial growth was observed in pouch swabs from 13 of 17 (76%) koalas, including four females without young, seven with pouch young and two with back young (i.e. permanently emerged from the pouch). growth of bacteria or yeasts was observed in pouch swabs from four koalas, each of which had experienced mortality of it ... | 1992 | 1602580 |
| [bacterial adherence to the alveolar and respiratory tract system]. | bacterial adherence to the alveolar and respiratory tract system was broadly divided into specific and non-specific adhesion, and effects such as aging were investigated. in specific adhesion, various types of lectin that specifically bind to oligosaccarids as bacterial receptors were used, and lectin specific sugers map of the alveolar and respiratory system were prepared. however, no quantitative difference in oligosaccarids distribution was noted between elderly and young subjects. meanwhile, ... | 1992 | 1602653 |
| therapies for radiation injuries: research perspectives. | exposure to radiation damages the immune, hematopoietic, and gastrointestinal components of the host defense system. this may lead to serious endogenous or exogenous infections. when radiation injury is combined with other physical trauma, e.g., burn or wound, the resulting damage to these systems is synergistic, and treatment for infection requires multiple approaches. this paper reviews successful single and combined therapeutic modalities for infections in irradiated mice and irradiated mice ... | 1992 | 1603404 |
| pyogenic hepatic abscess and septic pulmonary emboli associated with klebsiella ozaenae bacteremia. | we have reported a case of cryptogenic liver abscess with bacteremia and septic pulmonary emboli due to klebsiella ozaenae. this organism has not previously been reported as a cause of intra-abdominal infection and this is only the eighth reported case of bacteremia. k ozaenae is generally considered an opportunist of low virulence and a respiratory tract colonizer implicated in ozena (atrophic rhinitis). more information is required to understand the epidemiology and pathogenicity of human dise ... | 1992 | 1604394 |
| purification and characterization of a catalase-peroxidase from the fungus septoria tritici. | three classes of heme proteins, commonly designated hydroperoxidases, are involved in the metabolism of hydrogen peroxide: catalases, peroxidases, and catalase-peroxidases. while catalases and peroxidases are widely spread in animals, plants, and microorganisms, catalase-peroxidases were characterized only in prokaryotes. we report here, for the first time, on a catalase-peroxidase in a eukaryotic organism. the enzyme was purified from the fungal wheat pathogen septoria tritici, and is one of th ... | 1992 | 1605641 |
| prenatal microbiological risk factors associated with preterm birth. | to study the vaginal flora of pregnant women at 22-28 weeks gestation to determine whether the presence of specific micro-organisms is significantly associated with preterm birth and prelabour rupture of the membranes. | 1992 | 1606115 |
| bacteriological quality of infant feeding bottle-contents and teats in addis abeba, ethiopia. | bacteriological quality of 244 infant feeding-bottles and 61 teats were studied from january 1989 to november 1989. samples were collected from feeding-bottles of babies who were brought by nursing mothers to clinics and hospitals for varying complaints. of the 244 bottle-content samples, 144 (59%) harboured more than 2 x 10(6) colonies of bacteria per ml. of samples. the predominant bacterial isolates both from bottle-contents and teat-swabs were the coliform group of bacteria, such as e. coli, ... | 1992 | 1606947 |
| prevalence of a plasmid-mediated type ii dihydrofolate reductase gene among trimethoprim-resistant urinary pathogens in greek hospitals. | the genetic basis of trimethoprim resistance was examined in 24 klebsiella pneumoniae, 27 enterobacter cloacae, five enterobacter aerogenes and nine serratia marcescens urinary isolates from five hospitals in greece. analysis of the 65 isolates by serotyping and phage-typing identified 53 distinct strains. thirty-eight isolates (15 k. pneumoniae, 19 e. cloacae, two e. aerogenes and two s. marcescens) hybridized with a probe specific for a gene encoding type ii dihydrofolate reductase (dhfr). thr ... | 1992 | 1607329 |
| [the pathogen spectrum and its resistance behavior in children with urinary tract infections in angola]. | in 225 children (135 boys, 90 girls) suffering from clinical relevant urinary tract infection the bacterial spectrum and resistance behaviour to routinely used antibiotics were evaluated. in 65.4% of the patients a significant bacteriuria was found: e. coli (34.6%), proteus (22.3%), klebsiella (14.6%), citrobacter (9.2%), enterobacter (5.4%) and pseudomonas (5.4%). in testing a high resistance of bacterias to trimethoprim/sulfamethoxazol, ampicillin, and gentamycin was found, whereas good suscep ... | 1992 | 1608185 |
| reduction of campylobacter jejuni colonization of chicks by cecum-colonizing bacteria producing anti-c. jejuni metabolites. | cecum-colonizing bacteria were isolated from campylobacter jejuni-free white leghorn (gallus domesticus) laying hens and screened for the ability to produce anti-c. jejuni metabolites. nine isolates were obtained that possessed this characteristic. the peroral administration of the nine isolates as a mixture (ca. 10(9) per chick) to 1-day-old chicks was followed 1 week later by peroral inoculation of campylobacter jejuni (ca. 10(9) per chick) to determine if the cecal isolates could protect chic ... | 1992 | 1610187 |
| liver transplantation restores low serum levels of very low density and high density lipoproteins in end-stage primary biliary cirrhosis. | amounts of serum lipids were determined in 10 women suffering from end-stage primary biliary cirrhosis (pbc) in order to evaluate the concentrations of and changes in very low density (vldl), high density (hdl) lipoprotein cholesterol and apoprotein a-i before and after liver transplantation. the concentrations of some preoperative serum total lipids, especially hdl cholesterol and vldl triglyceride, and apoprotein a-i, were significantly lower, but those of serum total triglycerides and cholest ... | 1992 | 1610540 |
| screening method for beta-lactamase substrate profiles. | a disc diffusion method, based on the idea of klundert, for screening of substrate profiles of beta-lactamases was developed in order to perform epidemiological studies. the method was tested against 30 different reference beta-lactamases and 59 clinical isolates known to produce tem-1, shv-1 and bro-1. the reproducibility and discriminating power of the disc diffusion method made it possible to differentiate between eight types of substrate profiles for the 30 reference beta-lactamases and to d ... | 1992 | 1610546 |
| loracarbef (ly163892) versus amoxicillin/clavulanate in the treatment of acute purulent bacterial bronchitis. | in this single-blind study, 488 patients with acute bronchitis were randomly assigned to receive 400 mg of loracarbef twice daily or 500/125 mg of amoxicillin/clavulanate three times daily for seven days. treatment efficacy was evaluated in 98 patients treated with loracarbef and in 99 treated with amoxicillin-clavulanate in whom pretreatment positive cultures of pathogens susceptible to both study drugs were found. streptococcus pneumoniae, haemophilus influenzae, moraxella (branhamella) catarr ... | 1992 | 1611641 |
| in vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. | the in vitro activity of cefquinome, a new aminothiazolyl cephalosporin with a c-3 bicyclic pyridinium group, was compared with ceftazidime, cefpirome, and cefepime. cefquinome inhibited members of the enterobacteriaceae at less than or equal to 0.5 microgram/ml for escherichia coli, klebsiella pneumoniae, k. oxytoca, citrobacter diversus, salmonella shigella, proteus mirabilis, morganella, and providencia. although most citrobacter freundii and enterobacter cloacae were inhibited by less than 2 ... | 1992 | 1611848 |
| pyocolpos. | | 1992 | 1612682 |
| septic cholangitis and peritonitis in a gelding. | an 8-year-old arabian gelding with septic cholangitis and peritonitis was successfully treated with trimethoprim/sulfadiazine. the gelding was referred for evaluation of signs of abdominal pain, icterus, fever, and weight loss. peritoneal fluid analysis revealed septic and suppurative peritonitis. culture of the peritoneal fluid yielded escherichia coli and klebsiella pneumoniae, which were sensitive to trimethoprim/sulfadiazine. on the basis of results of hepatic ultrasonography, a diagnosis of ... | 1992 | 1612992 |
| [a study on in vitro antibacterial activity and clinical usefulness in respiratory tract infections of panipenem/betamipron, a newly synthesized carbapenem antibiotic]. | panipenem/betamipron (papm/bp) is a combination drug of papm, a new parenteral carbapenem antibiotic and bp, an amino acid derivative at a weight ratio of 1:1. its in vitro antibacterial activities against clinically isolated respiratory pathogenic bacteria were determined. it was superior to imipenem (ipm) in the in vitro antibacterial activities against haemophilus influenzae, haemophilus parainfluenzae, branhamella catarrhalis, staphylococcus aureus including mrsa, klebsiella pneumoniae, serr ... | 1992 | 1613967 |
| [a clinical study on panipenem/betamipron in chronic respiratory tract infections]. | panipenem/betamipron (cs-976, papm/bp), a new carbapenem antibiotic, was administered a single dose of 500 mg or 750 mg via intravenous drip infusion twice a day for treatment of chronic respiratory infection to study its clinical efficacy, bacteriological efficacy and safety. twenty nine cases were studied for the efficacy evaluation. only the safety evaluation was made in 6 cases which were judged to be unsuitable, because in some of them pneumonia and other diseases were not specified as the ... | 1992 | 1613969 |
| binding of a bacterial acylpoly(1,3)galactoside to human blood leucocytes. | the binding of a 34-kda (mol. wt.) acylpoly(1,3)galactoside (apg) extracted from a membrane proteoglycan of klebsiella pneumoniae to human blood leucocytes was investigated. apg is made of a long poly(1,3)galactose chain, a core-like region and a lipid moiety which comprises two glucosamine residues bound to a phosphate group and two beta oh myristic acids. fluoresceinated apg was shown to bind preferentially to monocytes and to a lesser extent to polymorphonuclear neutrophils, as determined by ... | 1992 | 1615280 |