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epidemiological investigation and genotype of chlamydia exposure in pigeons in three provinces in northern china.chlamydia is considered as one of the most widely prevalent zoonotic pathogens. it can spread from infected birds to human beings through direct or indirect contact with fecal shedding of chlamydia. however, data concerning prevalence and genotypes of chlamydia in pigeons are limited. in the present study, a total of 963 serum samples was collected from jilin province, liaoning province, and inner mongolia autonomous region (imar) in china between august 2015 and december 2016 and the seropreval ...201829350589
disclosing respiratory coinfections: a broad-range panel assay for avian respiratory pathogens on a nanofluidic pcr platform.respiratory syndromes (rs) are among the most significant pathological conditions in food animals and are caused by complex coactions of pathogens and environmental factors. in poultry, low pathogenic avian influenza a viruses, metapneumoviruses, infectious bronchitis virus, infectious laryngotracheitis virus, mycoplasma spp. escherichia coli and/or ornithobacterium rhinotracheale (ort) in turkeys, are considered as key co-infectious agents of respiratory syndromes. aspergillus sp., pasteurella ...201829350071
a cross sectional study on dutch layer farms to investigate the prevalence and potential risk factors for different chlamydia species.in poultry several chlamydia species have been detected, but chlamydia psittaci and chlamydia gallinacea appear to be most prevalent and important. chlamydia psittaci is a well-known zoonosis and is considered to be a pathogen of poultry. chlamydia gallinacea has been described more recently. its avian pathogenicity and zoonotic potential have to be further elucidated. within the netherlands no data were available on the presence of chlamydia on poultry farms. as part of a surveillance programme ...201829324884
circulating and broncho-alveolar interleukin-6 in relation to body temperature in an experimental model of bovine chlamydia psittaci infection.in rodent models of experimentally induced fever, the important role of interleukin-6 (il-6) as a circulating endogenous pyrogen is well established. studies employing larger animal species and real infections are scarce. therefore, we assessed bioactive il-6 in peripheral blood and in broncho-alveolar lavage fluid (balf) of calves after intra-bronchial inoculation with vital chlamydia psittaci (cp), with inactivated cp, or with bgm cells. only calves inoculated with vital cp developed fever (pe ...201729281663
underdiagnosis of chlamydia trachomatis and chlamydia psittaci revealed by introduction of respiratory multiplex pcr assay with chlamydiaceae family primers.we describe unanticipated detection of respiratory infection with chlamydia trachomatis and chlamydia psittaci after introduction of respiratory multiplex polymerase chain reaction assay that includes chlamydiaceae family primers. we detected cases of pediatric c. trachomatis and of adult c. psittaci infection in patients with previously unrecognized risk factors. directed testing for c. trachomatis and c. psittaci based on clinical features and risk factors alone is likely to miss the majority ...201729258707
zoonotic agents in feral pigeons (columba livia) from costa rica: possible improvements to diminish contagion risks.most studies on zoonotic agents in pigeons have been conducted in the palearctic region, but the scarcity of data is notorious in the neotropical region, where these birds can breed all year around and are in close contact with humans. in this study, we used a combination of culture-dependent and culture-independent methods to identify infectious agents in 141 fecal samples from pigeons collected at four urban parks from costa rica. of these we identified 34 positive samples for salmonella enter ...201829243991
the 2017 doyne lecture: the orbit as a window to systemic disease.a very large number of disorders affect the orbit, and many of these occur in the setting of systemic disease. this lecture covers selected aspects of orbital diseases with systemic associations in which the author has a particular clinical or research interest. spontaneous orbital haemorrhage often occurs in the presence of bleeding diatheses. thrombosis of orbital veins and ischaemic necrosis of orbital and ocular adnexal tissues occur with thrombophilic disorders, vasculitis, and certain bact ...201729125145
co-infection of chlamydia psittaci with h9n2, ort and aspergillus fumigatus contributes to severe pneumonia and high mortality in spf chickens.since 2007, most areas of china have seen outbreaks of poultry airsacculitis, which causes hugely economic losses to the poultry industry. however, there are no effective measures to combat the problem. in this study, 105 rations were collected to isolate aspergillus spp. from the diseased farms. in subsequent experiments, spf chickens were inoculated with ornithobacterium rhinotracheale (ort), chlamydia psittaci (c. psittaci) and aspergillus fumigatus (a. fumigatus), and mortality rate, body we ...201729070907
equine chlamydiosis-an emerging infectious disease requiring a one health surveillance approach.psittacosis is a rare but potentially fatal zoonosis caused by chlamydia psittaci, an organism that is typically associated with bird contact. however c. psittaci is capable of infecting other non-avian hosts, such as horses, sheep, cattle and goats. stud staff and veterinarians have significant exposure to parturient animals and reproductive materials in their routine work. to investigate the zoonotic potential associated with the emergence of c. psittaci as an abortifacient agent in horses, we ...201828984040
the jak/stat3 signaling pathway mediates inhibition of host cell apoptosis by chlamydia psittaci infection.the jak-stat3 signaling pathway is a key regulator of cell growth, motility, migration, invasion and apoptosis in mammalian cells. infection with intracellular pathogens of the genus chlamydia can inhibit host cell apoptosis, and here we asked whether the jak-stat3 pathway participates in chlamydial anti-apoptotic activity. we found that, compared with uninfected cells, levels of jak1 and stat3 mrna as well as total and phosphorylated jak1 and stat3 protein, were significantly increased in c. ps ...201728981630
chlamydia psittaci (psittacosis) as a cause of community-acquired pneumonia: a systematic review and meta-analysis.psittacosis is a zoonotic infectious disease caused by the transmission of the bacterium chlamydia psittaci from birds to humans. infections in humans mainly present as community-acquired pneumonia (cap). however, most cases of cap are treated without diagnostic testing, and the importance of c. psittaci infection as a cause of cap is therefore unclear. in this meta-analysis of published cap-aetiological studies, we estimate the proportion of cap caused by c. psittaci infection. the databases me ...201728946931
ocular adnexal marginal zone lymphoma of mucosa-associated lymphoid tissue.ocular adnexal lymphomas are a group of heterogeneous neoplasms representing approximately 1-2% of non-hodgkin lymphomas and 8% of extranodal lymphomas. the incidence of primary ocular adnexal lymphoid tumors has raised over the last decades, and this could be probably attributed to the more sophisticated diagnostic techniques. due to the wide spectrum of clinical manifestations, ocular tissue biopsy is important in order to set a precise diagnosis based on histological, immunophenotypical and, ...201728939925
development and evaluation of rapid novel isothermal amplification assays for important veterinary pathogens: chlamydia psittaci and chlamydia pecorum.chlamydia psittaci and chlamydia pecorum are important veterinary pathogens, with the former also being responsible for zoonoses, and the latter adversely affecting koala populations in australia and livestock globally. the rapid detection of these organisms is still challenging, particularly at the point-of-care (poc). in the present study, we developed and evaluated rapid, sensitive and robust c. psittaci-specific and c. pecorum-specific loop mediated isothermal amplification (lamp) assays for ...201728929022
compendium of measures to control chlamydia psittaci infection among humans (psittacosis) and pet birds (avian chlamydiosis), 2017.psittacosis, also known as parrot fever and ornithosis, is a bacterial infection that can cause severe pneumonia and other serious health problems in humans. it is caused by chlamydia psittaci. reclassification of the order chlamydiales in 1999 into 2 genera (chlamydia and chlamydophila) was not wholly accepted or adopted. this resulted in a reversion to the single, original genus chlamydia, which now encompasses all 9 species including chlamydia psittaci. during 2003-2014, 112 human cases of ps ...201728891690
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