Publications

TitleAbstractYear
Filter
PMID
Filter
bartonellosis, an increasingly recognized zoonosis.cat scratch disease is the most common zoonotic infection caused by bartonella bacteria. among the many mammals infected with bartonella spp., cats represent a large reservoir for human infection, as they are the main reservoir for bartonella henselae, bartonella clarridgeiae and bartonella koehlerae. bartonella spp. are vector-borne bacteria, and transmission of b. henselae by cat fleas occurs mainly through infected flea faeces, although new potential vectors (ticks and biting flies) have been ...201020148999
presence of bartonella species and rickettsia species dna in the blood, oral cavity, skin and claw beds of cats in the united states.the purpose of this study was to determine the prevalence of bartonella species and rickettsia species dna in the blood, oral cavity, skin and claw beds of feral cats without evidence of skin disease that were housed in alabama (n = 24), florida (n = 27) and colorado (n = 32). samples were assessed by use of polymerase chain reaction assays. the bartonella species igg prevalence was also determined. while bartonella species dna was not amplified from any sample from colorado cats, it was commonl ...200920178489
inoculation bartonellosis in an adult: a case report.cat-scratch disease (csd) and bacillary angiomatosis (ba) are caused by a gram-negative bacilli classified under the genus bartonella (formerly rochalimaea). patient history, symptoms, and histopathology often fall along a continuum; therefore, both conditions should be considered in the differential diagnosis. we report a case of an 83-year-old immunocompetent woman who presented with a pyogenic granuloma-like lesion on her dorsal left wrist. the histologic differential diagnosis included an in ...201020184210
flea-associated zoonotic diseases of cats in the usa: bartonellosis, flea-borne rickettsioses, and plague.cat-scratch disease, flea-borne typhus, and plague are three flea-associated zoonoses of cats of concern in the usa. although flea concentrations may be heaviest in coastal and temperate climates, fleas and flea-borne disease agents can occur almost anywhere in the usa. understanding flea-borne pathogens, and the associated risks for owners and veterinarians, is important to reduce the likelihood of zoonotic infection.201020185369
fleas and flea-borne diseases.flea-borne infections are emerging or re-emerging throughout the world, and their incidence is on the rise. furthermore, their distribution and that of their vectors is shifting and expanding. this publication reviews general flea biology and the distribution of the flea-borne diseases of public health importance throughout the world, their principal flea vectors, and the extent of their public health burden. such an overall review is necessary to understand the importance of this group of infec ...201020189862
[study on the prevalence and genotypes of bartonella species in rodent hosts from fujian coastal regions].to investigate bartonella infection in rodent hosts from different environments and types of climate in fujian coastal regions. genetypes of the bartonella strains was also studied to provide scientific basis for prevention and control of the correlated diseases.200920193373
a report of cat scratch disease in korea confirmed by pcr amplification of the 16s-23s rrna intergenic region of bartonella henselae.we report a case of cat scratch disease in an 8-yr-old girl who presented with fever and enlargement of both axillary lymph nodes. both aerobic and anaerobic cultures of the lymph node aspirate were negative for microbial growth. gram staining and warthin-starry silver staining did not reveal any organism. purified dna from the pcr-amplicon of the 16s-23s rrna intergenic region was sequenced and showed 99.7% identity with the corresponding sequence of bartonella henselae strain houston-1. our fi ...201020197720
[neuroretinitis in cat-scratch disease]. 201020199895
update on emerging infections: news from the centers for disease control and prevention. bartonella quintana in body lice and head lice from homeless persons, san francisco, california, usa. 201020201124
genome dynamics of bartonella grahamii in micro-populations of woodland rodents.rodents represent a high-risk reservoir for the emergence of new human pathogens. the recent completion of the 2.3 mb genome of bartonella grahamii, one of the most prevalent blood-borne bacteria in wild rodents, revealed a higher abundance of genes for host-cell interaction systems than in the genomes of closely related human pathogens. the sequence variability within the global b. grahamii population was recently investigated by multi locus sequence typing, but no study on the variability of p ...201020202191
bartonella spp. transmission by ticks not established.bartonella spp. infect humans and many animal species. mainly because pcr studies have demonstrated bartonella dna in ticks, some healthcare providers believe that these microorganisms are transmitted by ticks. b. henselae, in particular, is regarded as being present in and transmissible by the ixodes scapularis tick. the presence of a microbial agent within a tick, however, does not imply that the tick might transmit it during the course of blood feeding and does not confer epidemiologic import ...201020202410
potential for tick-borne bartonelloses.as worldwide vectors of human infectious diseases, ticks are considered to be second only to mosquitoes. each tick species has preferred environmental conditions and biotopes that determine its geographic distribution, the pathogens it vectors, and the areas that pose risk for tick-borne diseases. researchers have identified an increasing number of bacterial pathogens that are transmitted by ticks, including anaplasma, borrelia, ehrlichia, and rickettsia spp. recent reports involving humans and ...201020202411
candidatus bartonella mayotimonensis and endocarditis.we describe a new bartonella species for which we propose the name candidatus bartonella mayotimonensis. it was isolated from native aortic valve tissue of a person with infective endocarditis. the new species was identified by using pcr amplification and sequencing of 5 genes (16s rrna gene, ftsz, rpob, glta, and internal transcribed spacer region).201020202430
bartonella spp. infection in hiv positive individuals, their pets and ectoparasites in rio de janeiro, brazil: serological and molecular study.bartonella is the agent of cat-scratch disease, but is also responsible for more severe conditions such as retinitis, meningoencephalitis, endocarditis and bacillary angiomatosis. its seroprevalence is unknown in brazil.201020206113
disseminated bartonellosis presenting as neuroretinitis in a young adult with human immunodeficiency virus infection.rapidly declining visual acuity from neuroretinitis should prompt aggressive diagnostic intervention to preserve eyesight. we present a young adult with human immunodeficiency virus (hiv) infection in whom neuroretinitis was the presenting feature of disseminated bartonellosis. tissue biopsy was required to establish the diagnosis and directed therapy was associated with restored vision.201020216243
detection of multiple bartonella species in digestive and reproductive tissues of fleas collected from sympatric mammals.at least 12 species in the genus bartonella are zoonotic pathogens that may be transmitted among mammalian hosts by fleas or other arthropods. apparent host specificity by some bartonella species to mammalian hosts has been observed, and the detection of multiple bartonella species in mammalian fleas suggests that fleas take bloodmeals from a variety of host species. however, many flea species are observed to parasitize a narrow host range. therefore, we suspect that fleas may acquire bartonella ...201020220787
evaluation of sensitivity, specificity and cross-reactivity in bartonella henselae serology. 201020223899
prevalence and seasonality of tick-borne pathogens in questing ixodes ricinus ticks from luxembourg.in europe, ixodid ticks are important arthropod vectors of human and animal pathogens, but comprehensive studies of the prevalence of all relevant pathogens in central europe are scarce. as a result of ecological changes, the incidences of tick-borne infections are expected to increase. in this study, 1,394 nymphal and adult ixodes ricinus ticks sampled monthly during the active season from 33 ecologically distinct collection sites throughout luxembourg were screened for all human tick-borne pat ...201020228110
bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings.to provide a review of clinically relevant observations related to bartonella species as emerging pathogens in veterinary and human medicine.201020230432
conventional and molecular diagnostic testing for the acute neurologic patient.the aim of this review is to describe and evaluate both conventional and molecular diagnostic testing utilized in dogs and cats with acute neurologic diseases. various types of polymerase chain reaction (pcr) are explored along with novel molecular diagnostic testing that ultimately may prove useful in the critical care setting.201020230434
feline hemotropic mycoplasmas.to describe the current understanding of the etiology, pathogenesis, diagnosis, and treatment of feline hemotropic mycoplasmosis (feline infectious anemia).201020230435
detection and genetic diversity of bartonella vinsonii subsp. berkhoffii strains isolated from dogs in ankara, turkey.bartonella vinsonii subsp. berkhoffii has been identified as an important pathogen in dogs and is an emerging pathogen in people with zoonotic potential. this study aimed to isolate bartonella spp. in 250 blood samples collected from dogs in the province of ankara, turkey, between october 2006 and march 2007. the typing of the 23 isolates was carried out by pcr for citrate synthase (glta) and the 16s-23s intergenic transcribed spacer (its). the prevalence of bacteremia was 9.2% in 250 samples. a ...201020234114
human bartonella infection and african sleeping sickness (field and laboratory experiences). 194620274014
the treatment of carrion's disease with large transfusions. 194720284814
a note on two blood parasites of cattle (spirochaeta theileri and bartonella bovis) recorded for the first time in australia. 194620290808
reticulo-endothelial immune serum (reis); an experimental anemia in bartonella infected rats produced by anti-blood immune serum. 194720292837
effects of prolonged formalin fixation on the immunohistochemical detection of infectious agents in formalin-fixed, paraffin-embedded tissues.immunohistochemistry is commonly used to detect and characterize infectious agents in diagnostic pathology. the principal advantage of immunohistochemistry over other antigen detection techniques is the ability to identify antigen within the context of histologic lesions. although epitope masking attributed to formalin fixation, especially prolonged fixation, has been considered a limiting factor in diagnostic immunohistochemistry, only a few studies have evaluated the immunohistochemical detect ...201020332424
multi-locus sequence typing of a geographically and temporally diverse sample of the highly clonal human pathogen bartonella quintana.bartonella quintana is a re-emerging pathogen and the causative agent of a variety of disease manifestations in humans including trench fever. various typing methods have been developed for b. quintana, but these tend to be limited by poor resolution and, in the case of gel-based methods, a lack of portability. multilocus sequence typing (mlst) has been used to study the molecular epidemiology of a large number of pathogens, including b. henselae, a close relative of b. quintana. we developed a ...201020333257
[a clinical case of spontaneous involution of systemic cat scratch disease].typical cat-scratch disease (csd) manifests as regional lymphadenopathy following cat scratch and sometimes associated with mild fever. there is a lot of atypical manifestations and some of those have systemic involvement. hepatosplenic csd is a systemic presentation associating fever of unknown origin with nodules in the liver and/or the spleen. ultrasound abdominal examination shows nodules (3-30 mm) in the spleen and/or in the liver. diagnostic is based on serology for b henselae (always igg ...201020344917
blood donor infected with bartonella henselae. 201020345384
isolation and characterization of bartonella strains in cats in italy.bartonella henselae and bartonella clarridgeiae were isolated in two cats in sardinia, italy. infection by b. clarridgeiae was characterized by fever and submandibular lymph nodes enlargement while b. henselae infection was asymptomatic. this is the first report of b. clarridgeiae in a cat in italy and the first isolation of b. henselae and b. clarridgeiae in sardinia.201020345572
bartonella spp. infections, thailand. 201020350414
functional dissection of the conjugative coupling protein trwb.the conjugative coupling protein trwb is responsible for connecting the relaxosome to the type iv secretion system during conjugative dna transfer of plasmid r388. it is directly involved in transport of the relaxase trwc, and it displays an atpase activity probably involved in dna pumping. we designed a conjugation assay in which the frequency of dna transfer is directly proportional to the amount of trwb. a collection of point mutants was constructed in the trwb cytoplasmic domain on the basis ...201020363945
bacillary angiomatosis in an immunosuppressed dog.abstract a dog being treated with immunosuppressive doses of prednisone and azathioprine for pancytopenia of unknown origin, developed, over a 2-week period, multiple erythematous nodular lesions in the skin including footpads. skin samples revealed lesions identical to those of human bacillary angiomatosis (ba). the nodules were composed of multifocal proliferations of capillaries, each lined by protuberant endothelial cells. the capillary clusters were separated by an oedematous connective tis ...201020374571
bartonella vinsonii subsp. berkhoffii and bartonella henselae bacteremia in a father and daughter with neurological disease.abstract:201020377863
color doppler pseudolymphomatous manifestations of the cat scratch disease.cat scratch disease (csd) is an infectious illness, caused by the bartonella henselae bacterium. besides the common infective symptoms, swelling in the axillary and cervical region is very common and is usually evaluated by color doppler us (cdus) (among other diagnostic methods). the aim of this work is to present ultrasound findings of the cat scratch disease. during 2002 and 2003, we followed four patients (three male and one female) by cdus, with different manifestations of the disease. the ...200920380135
the ecology of bartonella spp. infections in two rodent communities in the mazury lake district region of poland.prevalence and abundance of bartonella spp. infections were studied over a 3-year period in woodland and grassland rodents in north-eastern poland. prevalence of bacterial infections was similar in the two rodent communities, with one leading host species in each habitat (46.3% in apodemus flavicollis versus 29.1% in myodes glareolus in forest, or 36.9% in microtus arvalis versus 13.7% in mi. oeconomus in grassland). prevalence/abundance of infections varied markedly across the 3 years with 2006 ...201020388232
evaluation of topical application of 10% imidacloprid-1% moxidectin to prevent bartonella henselae transmission from cat fleas.to determine whether monthly topical administration of a combination of 10% imidacloprid and 1% moxidectin would lessen flea (ctenocephalides felis) transmission of bartonella henselae among cats.201020392182
molecular evidence of perinatal transmission of bartonella vinsonii subsp. berkhoffii and bartonella henselae to a child.bartonella vinsonii subsp. berkhoffii, bartonella henselae, or dna of both organisms was amplified and sequenced from blood, enrichment blood cultures, or autopsy tissues from four family members. historical and microbiological results support perinatal transmission of bartonella species in this family. it is of clinical relevance that bartonella spp. may adversely influence human reproductive performance.201020392912
an immunocompromised murine model of chronic bartonella infection.bartonella are ubiquitous gram-negative pathogens that cause chronic blood stream infections in mammals. two species most often responsible for human infection, b. henselae and b. quintana, cause prolonged febrile illness in immunocompetent hosts, known as cat scratch disease and trench fever, respectively. fascinatingly, in immunocompromised hosts, these organisms also induce new blood vessel formation leading to the formation of angioproliferative tumors, a disease process named bacillary angi ...201020395436
a "silent culture-negative" abdominal aortic mycotic aneurysm: rapid detection of bartonella species using pcr and high-throughput mass spectrometry.a gram-negative, rod-shaped microorganism was detected in a 69-year-old man suffering from chronic back pain but otherwise exhibiting no signs of infection. the bacterium could not be identified using any routine diagnostic modality. a research use only application utilizing pcr and mass spectrometry was performed on nucleic acid extracted from the tissue sample. these studies resulted in the implication of bartonella quintana as the underlying cause of the infection. b. quintana is not a well-k ...201020397506
the batr/bats two-component regulatory system controls the adaptive response of bartonella henselae during human endothelial cell infection.here, we report the first comprehensive study of bartonella henselae gene expression during infection of human endothelial cells. expression of the main cluster of upregulated genes, comprising the virb type iv secretion system and its secreted protein substrates, is shown to be under the positive control of the transcriptional regulator batr. we demonstrate binding of batr to the promoters of the virb operon and a substrate-encoding gene and provide biochemical evidence that batr and bats const ...201020418395
[optic neuritis].optic neuritis is a common feature of inflammatory diseases of the central nervous system such as multiple sclerosis and neuromyelitis optica. it may also reveal systemic inflammatory disorders including sarcoidosis, lupus, sjögren's syndrome, behçet's disease, or infections such as neurosyphilis or with bartonella. in some patients diagnostic workup remains negative leading to the diagnosis of an idiopathic optic neuritis. a painful loss of vision is the usual clinical presentation. the fundosc ...201020434241
rare infections mimicking ms.the diagnosis of multiple sclerosis (ms), despite well defined clinical criteria is not always simple. on many occasions it is difficult to differentiate ms from various non-ms idiopathic demyelinating disorders, specific and infectious inflammatory diseases or non-inflammatory demyelinating diseases. clinicians should be aware of various clinical and mri "red flags" that may point to the other diagnosis and demand further diagnostic evaluation. it is generally accepted that atypical clinical sy ...201020439131
[bartonella spp. as a zoonotic pathogens transmitting by blood-feeding arthropods].prior to 1993, bartonella bacilliformis was the only member of the bartonella genus. now, the genus bartonella currently contains over 30 species of gram-negative bacteria that parasitize mammalian erythrocytes and endothelial cells. bartonella spp. have been isolated from a variety of mammal species, most often from rodents, ruminants and carnivores, and these animals are implicated as reservoirs for the genus bartonella. the persistent bacteriemia is more readily documented in the primary rese ...201020450002
blood parasites of mound-building mouse, mus spicilegus petényi, 1882 (mammalia, rodentia).mound-building mice, mus spicilegus, were studied for the blood parasites in eastern slovakia, vicinity kechnec village near kosice town (kosická kotlina basin, 21 degrees 14' e, 48 degrees 33' n) during years 2002-2005. overall, 251 specimens were examined. the parasites were detected using microhematokrit centrifugation technique and on the giemsa's method stained blood smears and light microscopy. the parasites were found in 3.57% of specimens; 1.20% of mice were infected with bartonella sp., ...201020450010
rapid diversification by recombination in bartonella grahamii from wild rodents in asia contrasts with low levels of genomic divergence in northern europe and america.bartonella is a genus of vector-borne bacteria that infect the red blood cells of mammals, and includes several human-specific and zoonotic pathogens. bartonella grahamii has a wide host range and is one of the most prevalent bartonella species in wild rodents. we studied the population structure, genome content and genome plasticity of a collection of 26 b. grahamii isolates from 11 species of wild rodents in seven countries. we found strong geographic patterns, high recombination frequencies a ...201020465583
prevalence of selected infectious agents in cats in ireland.vector-borne bacterial and rickettsial agents and toxoplasma gondii, are common organisms in cats. some are potentially zoonotic or may be transmitted via blood transfusion. the current study investigated the prevalence of these agents in cats from dublin, ireland, for which no published data exists. whole blood (n=116) and sera (n=83) samples were obtained from 121 cats. dna was extracted from blood and assayed using polymerase chain reaction techniques for anaplasma species, bartonella species ...201020472484
seroprevalence of bartonella in eastern china and analysis of risk factors.bartonella infections are emerging in the zhejiang province of china. however, there has been no effort to date to explore the epidemiology of these infections in this region, nor to identify risk factors associated with exposure to bartonella. the aim of this study was to investigate the seroprevalence of bartonella in both patients bitten by dogs and blood donors (for control) in eastern china, and to identify risk factors associated with exposure to bartonella. as no previous data for this re ...201020482887
who is this man? 201020507765
serous labyrinthitis as a manifestation of cat scratch disease: a case report.abstract : introduction : cat scratch disease is an infectious disease transmitted by young cats, in which the principal causative factor is bartonella henselae. the typical course of cat scratch disease is usually benign and self-limited and requires only supportive therapy. however, cases lasting up to 2 years have been reported, and more serious complications may occur. many manifestations of the disease have been reported by different medical disciplines. case presentation : a case of cat sc ...200920519021
identification of bartonella infections in febrile human patients from thailand and their potential animal reservoirs.to determine the role of bartonella species as causes of acute febrile illness in humans from thailand, we used a novel strategy of co-cultivation of blood with eukaryotic cells and subsequent phylogenetic analysis of bartonella-specific dna products. bartonella species were identified in 14 blood clots from febrile patients. sequence analysis showed that more than one-half of the genotypes identified in human patients were similar or identical to homologous sequences identified in rodents from ...201020519614
prevalence of bartonella species, rickettsia felis, haemoplasmas and the ehrlichia group in the blood of cats and fleas in eastern australia.to define the prevalence of bartonella spp., rickettsia felis, mycoplasma haemofelis, 'candidatus mycoplasma haemominutum' (mhm) and 'candidatus mycoplasma turicensis' (mtc) in cats and their fleas in eastern australia.201020529020
phylogenetics and population genetics of the louse fly, lipoptena mazamae, from arkansas, usa.louse flies, also known as deer keds (lipoptena mazamae rondani), infest cervids such as white-tailed deer, odocoileus virginianus and vector pathogens such as anaplasma and bartonella schoenbuchensis to cattle and humans, respectively. the population genetic structure of 30 l. mazamae collected from white-tailed deer in four regions of arkansas, u.s.a., designated by county boundaries, was examined using dna sequences of a 259-bp region of the mitochondrial dna rrna 16s gene. of the 259 nucleot ...201020534010
what's eating you? cat flea (ctenocephalides felis), part 1: clinical features and role as a disease vector. 201020540412
comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases.background. blood culture-negative endocarditis (bcne) may account for up to 31% of all cases of endocarditis. methods. we used a prospective, multimodal strategy incorporating serological, molecular, and histopathological assays to investigate specimens from 819 patients suspected of having bcne. results. diagnosis of endocarditis was first ruled out for 60 patients. among 759 patients with bcne, a causative microorganism was identified in 62.7%, and a noninfective etiology in 2.5%. blood was t ...201020540619
the trw type iv secretion system of bartonella mediates host-specific adhesion to erythrocytes.bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood. the alpha-proteobacterial genus bartonella comprises 21 species that cause host-specific intraerythrocytic bacteremia as hallmark of infection in their respective mammalian reservoirs, including the human-specific pathogens bartonella quintana and bartonella bacilliformis that cause trench fever and oroya fever, respectively. here, we have identifi ...201020548954
antimicrobial susceptibility by etest of bartonella henselae isolated from cats and human in japan.bartonella henselae, a small fastidious gram-negative bacillus, is the causative agent of cat-scratch disease (csd). because of difficulty in isolating the organism, there has been no report on its antibiotic susceptibility in japan. we determined the minimal inhibitory concentrations (mics) of eight antimicrobial agents against 32 isolates of b. henselae (31 from cats and one from a human in japan) by the etest method. mics of all 32 isolates were <0.016 μg/ml for minocycline and ranged from ≤0 ...201020567991
unknown fever and back pain caused by bartonella henselae in a veterinarian after a needle puncture: a case report and literature review.abstract bartonella henselae, the etiologic agent of cat-scratch disease, rarely causes back pain and is considered to be transmitted through animal scratches and bites. here we report a cat-scratch disease case possibly with an unusual route of transmission. the patient was a 32-year-old man, and he was working as a veterinarian in a private veterinary clinic. he sought for clinical help because of unknown fever and persistent back pain for at least a month after an accidental needle puncture. ...201120569013
rickettsia felis and bartonella clarridgeiae in fleas from new caledonia.dog fleas collected in new caledonia harbored flea-borne pathogens rickettsia felis and bartonella clarridgeiae in 81% and 5%, respectively.201120569017
enrichment culture and molecular identification of diverse bartonella species in stray dogs.using pre-enrichment culture in bartonella alpha-proteobacteria growth medium (bapgm) followed by pcr amplification and dna sequence identification that targeted a fragment of the citrate synthase gene (glta), we provide evidence of common bartonella infections and diverse bartonella species in the blood of stray dogs from bangkok and khon kaen, thailand. the overall prevalence of all bartonella species was 31.3% (60/192), with 27.9% (31/111) and 35.8% (29/81) in the stray dogs from bangkok and ...201020570065
association between bartonella species infection and disease in pet cats as determined using serology and culture.this study's objective was to determine whether a relationship exists between infection or seropositivity to bartonella species and clinical illness in cats. blood samples were obtained for bartonella species isolation and immunofluorescent antibody serology from 298 cats presenting to a tertiary referral hospital. medical records were searched and the history, physical examination findings and the results of diagnostic testing relating to the visit at which bartonella species testing was perfor ...201020570199
seroprevalence of bartonella vinsonii subsp. berkhoffii in urban and rural dogs in turkey.the seroprevalence of bartonella vinsonii subsp. berkhoffii was investigated in stray urban dogs and shepherd and farm guard dogs from rural areas sampled from 10 provinces of turkey. sera from 855 dogs were examined for the presence of anti-b. vinsonii subsp. berkhoffii antibodies by indirect fluorescent antibody test. overall, 56 (6.6%) of the 855 dogs examined, including 16 (3%) of the 522 stray dogs and 40 (12%) of the 333 rural dogs, were seropositive. this is the first report on prevalence ...201020574140
molecular mechanism of gentamicin resistance in bartonella henselae. 200920584166
expressive aphasia as a presentation of encephalitis with bartonella henselae infection in an immunocompetent adult.to show the first clinically reported case of cat scratch disease (csd) presenting as a focal neurologic deficit in an immunocompetent adult.201020589186
prevention of endemic canine vector-borne diseases using imidacloprid 10% and permethrin 50% in young dogs: a longitudinal field study.canine vector-borne diseases (cvbds) are highly prevalent and increasing in distribution worldwide. a longitudinal study was conducted in southern italy to determine the incidence of and protection against cvbd-causing pathogens in dogs treated with a combination of imidacloprid 10% and permethrin 50% (imper). one hundred eleven autochthonous young dogs were divided into group a (n=63) and group b (n=48), both groups containing dogs positive and negative for one or more cvbd-causing pathogens. a ...201020591573
molecular typing of bartonella henselae dna extracted from human clinical specimens and cat isolates in japan.bartonella henselae is the causative agent of cat scratch disease (csd). to clarify the population structure and relationship between human and cat strains of b. henselae, 55 specimens isolated in japan, including 24 b. henselae dna-positive clinical samples from csd patients and 31 b. henselae isolates from domestic cats, were characterized by multilocus sequence typing (mlst) and the 16s-23s trna-ala/trna-ile intergenic spacer (s1) sequence, which were used previously for strain typing of b. h ...201020602637
infective endocarditis in dogs: diagnosis and therapy.infective endocarditis (ie) is a bacterial disease that commonly occurs in dogs. difficulty in diagnosis and underreporting of ie in dogs contribute to the reported low prevalence rate of the disease. the mitral and aortic valves are the worst affected by ie. common causative microbial agents include staphylococcus spp, streptococcus spp, escherichia coli, and bartonella spp. congestive heart failure, immune-mediated disease, and thromboembolism are the major complications of ie. diagnosis of ie ...201020610018
does a feline leukemia virus infection pave the way for bartonella henselae infection in cats?domestic cats serve as the reservoir hosts of bartonella henselae and may develop mild clinical symptoms or none after experimental infection. in humans, b. henselae infection can result in self-limiting cat scratch disease. however, immunocompromised patients may suffer from more-severe courses of infection or may even develop the potentially lethal disease bacillary angiomatosis. it was reasoned that cats with immunocompromising viral infections may react similarly to b. henselae infection. th ...201020610682
identification of the feline humoral immune response to bartonella henselae infection by protein microarray.bartonella henselae is the zoonotic agent of cat scratch disease and causes potentially fatal infections in immunocompromised patients. understanding the complex interactions between the host's immune system and bacterial pathogens is central to the field of infectious diseases and to the development of effective diagnostics and vaccines.201020625509
neuroretinitis caused by bartonella henselae (cat-scratch disease) in a 13-year-old girl.cat-scratch disease-related neuroretinitis is a relatively unusual pathology, with suspicious clinical epidemiological and serological diagnosis. we present a case of an adolescent suffering from unilateral neuroretinitis associated with bartonella henselae infection characterized by abrupt loss of vision, optic disc swelling, and macular star exudates with optimal response to antibiotic treatment.201020628521
molecular detection of ehrlichia canis, anaplasma bovis, anaplasma platys, candidatus midichloria mitochondrii and babesia canis vogeli in ticks from israel.: ticks are vectors of important pathogens of human and animals. therefore, their microbial carriage capacity is constantly being investigated. the aim of this study was to characterize the diversity of domestic animal pathogens in ticks collected from vegetation and the ground, from different parts of israel. non-engorged questing adult ticks were collected from 13 localities. a total of 1196 ticks in 131 pools-83 pools of rhipicephalus turanicus and 48 of rhipicephalus sanguineus (with two to ...201120636417
[unilateral neuroretinitis revealing cat-scratch disease].we report a case of cat-scratch disease neuroretinitis. a 26-year-old man was referred for severe right visual loss. posterior segment examination showed a papilledema with macular edema. bartonella henselae immunoglobulin g testing was positive. four weeks of antibiotic therapy combining oral ciprofloxacin and doxycycline led to progressive resolution of the neuroretinitis and improvement in visual acuity. this report reminds that b. henselae infection can be the cause of neuroretinitis. its pr ...201120646795
[bilateral inguinal lymphadenopathy and erythema nodosum: an uncommon presentation of cat scratch disease].cat scratch disease is usually revealed by a proximal lymphadenopathy related to the inoculation site. we report a 22-year-old female who presented with erythema nodosum and bilateral inguinal lymphadenopathy. serologic test and lymph node pcr detection for bartonella henselae were negative. nevertheless, the patient received doxycycline and clinical manifestations rapidly resolved. a follow-up detection of igm and igg against bartonella henselae performed 1 month later was positive. this case r ...201120646798
oral shedding of bartonella in cats: correlation with bacteremia and seropositivity.cats are the main reservoirs of zoonotic bartonella henselae, b. clarridgeiae and b. koehlerae, transmitted among cats by cat fleas. no study has investigated the presence of bartonella in the saliva of bacteremic and non-bacteremic cats to correlate it to the level of bacteremia and the presence or absence of oral lesions. shelter cats from northern california (n=130) and michigan (n=50) were tested for bartonella bacteremia by blood culture, presence of bartonella antibodies and bartonella dna ...201020646879
hiv-negative case of bacillary angiomatosis with chronic hepatitis b.bacillary angiomatosis (ba) is an infectious disease which occurs predominantly in immunosuppressive patients and rarely in immunocompetent individuals. we had a case of ba who presented with a red cutaneous nodule on his left leg of which histopathological examination revealed marked lobular proliferation of capillaries throughout the interstitium and clusters of bacilli with hematoxylin-eosin and warthin-starry stains, respectively. antibody titer against bartonella henselae was 1/32. the only ...201020649715
bacillary angiomatosis in a pregnant woman. 201020650456
[application of warthin-starry stain, immunohistochemistry and transmission electron microscopy in diagnosis of cat scratch disease].to evaluate the diagnostic utility of warthin-starry silver stain, immunohistochemistry and transmission electron microscopy in the detection of human bartonella henselae infection and pathologic diagnosis of cat scratch disease (csd).201020654119
cat-scratch disease: ocular manifestations and visual outcome.to describe the intra-ocular manifestations of cat-scratch disease (csd) found at two uveitis reference centers in brazil. retrospective case series study. review of clinical records of patients diagnosed with csd in the uveitis department of são geraldo hospital and the ophthalmology department of the instituto de pesquisa clínica evandro chagas-fiocruz, from 2001 to 2008. in the 8-year period, 24 patients with the diagnosis of csd were identified. twelve patients were male and 12 female. the m ...201020668914
human isolates of bartonella tamiae induce pathology in experimentally inoculated immunocompetent mice.bartonella tamiae, a newly described bacterial species, was isolated from the blood of three hospitalized patients in thailand. these patients presented with headache, myalgia, anemia, and mild liver function abnormalities. since b. tamiae was presumed to be the cause of their illness, these isolates were inoculated into immunocompetent mice to determine their relative pathogenicity in inducing manifestations of disease and pathology similar to that observed in humans.201020673363
molecular evidence of bartonella infection in domestic dogs from algeria, north africa, by polymerase chain reaction (pcr).bartonella species are being recognized as important bacterial human and canine pathogens, and are associated with multiple arthropod vectors. bartonella dna extracted from blood samples was obtained from domestic dogs in algiers, algeria. polymerase chain reaction (pcr) and dna sequence analyses of the ftsz gene and the 16s-23s intergenic spacer region (its) were performed. three bartonella species: bartonella vinsonii subsp. berkhoffii, bartonella clarridgeiae, and bartonells elizabethae were ...201020682871
ocular bacillary angiomatosis in an immunocompromised man.an immunocompromised man presented with an inflammatory eyelid lesion. biopsy was performed; histopathology and special staining confirmed a diagnosis of bacillary angiomatosis. the man was treated with oral erythromycin, and the lesion resolved. the etiologic agents of bacillary angiomatosis are bartonella henselae and bartonella quintana, gram-negative coccobacilli. the organisms stain positively with the warthin-starry silver stain. lesions can be cutaneous or visceral and have been commonly ...201020683276
prevalence of selected vector-borne organisms and identification of bartonella species dna in north american river otters (lontra canadensis).trapper-killed north american river otters (lontra canadensis) in north carolina, usa, were screened for multiple vector-borne bacteria known to be pathogenic to mammals. blood was collected from 30 carcasses in 2006, from 35 in 2007, and from one live otter in 2008. samples were screened using conventional polymerase chain reaction (pcr) tests for dna from bartonella spp., ehrlichia spp., and spotted fever group rickettsia spp. all samples were negative for rickettsia spp. twelve of 30 samples ...201020688703
identification of candidate proteins for the diagnosis of bartonella henselae infections using an immunoproteomic approach.bartonella henselae is an emerging gram-negative facultative intracellular pathogen transmitted via ctenocephalides felis (cat fleas) or cat scratches. bartonellosis is present mainly in the form of cat scratch disease (csd), bacillary angiomatosis and infective endocarditis (ie). the methods used to diagnose b. henselae rely on culturing, immunofluorescent assays and molecular techniques. the objective of the present study was to identify candidate proteins for the serodiagnosis of bartonellosi ...201020695898
suspected needle stick transmission of bartonella vinsonii subspecies berkhoffii to a veterinarian. 201020695992
human coinfection with bartonella henselae and two hemotropic mycoplasma variants resembling mycoplasma ovis.two variants of an organism resembling the ovine hemoplasma, mycoplasma ovis, were detected by pcr in blood samples from a veterinarian in texas. coinfection with similar variants has been described in sheep. this represents the first report of human infection with this organism. the veterinarian was coinfected with bartonella henselae.201020702675
real-time and multiplex real-time polymerase chain reactions for the detection of bartonella henselae within cat flea, ctenocephalides felis, samples.bartonella henselae (rhizobiales: bartonellacae), the agent of cat-scratch disease, is an emerging bacterial pathogen which can be transmitted via infective faecal material of ctenocephalides felis bouché (siphonaptera: pulicidae). worldwide, b. henselae has been identified in 1-53% of felines and 2.9-17.4% of fleas. although culture is the routine method for detection, the procedure is time-consuming and is rarely used for isolation directly from flea vectors. the current study reports the deve ...201020704655
neuralgic amyotrophy associated with bartonella henselae infection. 201120710009
pcr amplification of bartonella koehlerae from human blood and enrichment blood cultures.abstract:201020735840
recombination within and between species of the alpha proteobacterium bartonella infecting rodents.bartonella infections from wild mice and voles (apodemus flavicollis, mi. oeconomus, microtus arvalis and myodes glareolus) were sampled from a forest and old-field habitats of eastern poland; a complex network of bartonella isolates, referrable to b. taylorii, b. grahamii, b. birtlesii and b. doshiae, was identified by the sequencing of a glta fragment, comparable to previous studies of bartonella diversity in rodents. nested clade analysis showed that isolates could be assigned to zero- and on ...201120740281
production of pernicious anaemia (bartonella anaemia) in rats by deficient feeding. 193020775541
skin diseases associated with bartonella infection: facts and controversies.the genus bartonella is composed of a series of species and subspecies. ten of them are responsible for human infections. the best-identified diseases are cat scratch disease (b henselae and possibly b clarridgeiae), trench fever (b quintana), bacillary angiomatosis (b quintana and b henselae), and the spectrum of verruga peruana, carrion disease, and oroya fever (b bacilliformis). controversies exist about the implication of a few other microorganisms being involved in these diseases. several o ...201020797506
bartonella genotypes in fleas (insecta: siphonaptera) collected from rodents in the negev desert, israel.fleas collected from rodents in the negev desert in southern israel were molecularly screened for bartonella species. a total of 1,148 fleas, collected from 122 rodents belonging to six species, were pooled in 245 pools based on flea species, sex, and rodent host species. two bartonella gene fragments, corresponding to rna polymerase b (rpob) and citrate synthase (glta), were targeted, and 94 and 74 flea pools were found positive by pcr, respectively. the bartonella 16s-23s internal transcribed ...201020802081
[traveler's fever associated with cervical adenomegaly and antibodies for bartonella sp in a brazilian patient returning from south africa].a large number of travelers visit the african continent annually for studying, tourism or business reasons. the authors report a case of cervical adenomegaly, hepatomegaly and splenomegaly associated with a two-week history of fever and seropositivity for bartonella sp in a 22-year-old female patient who returned from south africa after field work with primates in a wild area.201020802956
bartonella species, feline herpesvirus-1, and toxoplasma gondii pcr assay results from blood and aqueous humor samples from 104 cats with naturally occurring endogenous uveitis.toxoplasma gondii, bartonella henselae and feline herpesvirus-1 (fhv-1) have been implicated as causative agents in feline uveitis. the usefulness of serum and aqueous humor (ah) antibody testing for these agents is limited as antibodies can be detected in both healthy cats and cats with uveitis. very few studies using polymerase chain reaction (pcr) assays to amplify organism dna from samples from cats with uveitis have been performed. in this study, assays to detect t gondii antibodies, feline ...201020817587
arthropod-borne diseases associated with political and social disorder.the living conditions and the crowded situations of the homeless, war refugees, or victims of a natural disaster provide ideal conditions for the spread of lice, fleas, ticks, flies and mites. the consequence of arthropod infestation in these situations is underestimated. along with louse-borne infections such as typhus, trench fever, and relapsing fever, the relationship between acinetobacter spp.-infected lice and bacteremia in the homeless is not clear. murine typhus, tungiasis, and myiasis a ...201120822446
cat scratch disease and arthropod vectors: more to it than a scratch?cat scratch disease is a common infection, particularly in children, and clinicians need to be aware of its potential transmission to humans by arthropod vectors such as fleas and ticks in addition to animal bites and scratches. the absence of a vertebrate bite or scratch does not preclude infection with bartonella henselae.201020823366
[neuroretinitis in cat scratch disease].purpose: to present two cases of neuroretinitis in cat scratch disease we present two girls treated in department of ophthalmology of poznai university of medical sciences because of unilateral, painless decrease of vision. both patients presented following cat exposure fever and lymph nodes swelling. ophthalmoscopic findings was neuroretinitis (optic disc edema with the macular star). bartonella henselae antibody titers (igg) were elevated. csd is usually self-limited infection in immunocompete ...201020825068
bartonella spp.: throwing light on uncommon human infections.after 2 decades of bartonella research, knowledge on transmission and pathology of these bacteria is still limited. bartonella spp. have emerged to be important pathogens in human and veterinary medicine. for humans, b. henselae is considered to represent the most relevant zoonotic bartonella species and is responsible for cat scratch disease, bacillary angiomatosis, and other disorders. over the years, many bartonella species have been isolated from humans, cats, dogs, and other mammals, and in ...201120833105
bartonellosis diagnosis requires careful evaluation. 201020835501
Displaying items 2301 - 2400 of 2611