antibacterial activity of the essential oils of pistacia lentiscus used in moroccan folkloric medicine. | the essential oil of the leaves of pistacia lentiscus, collected from the middle atlas in morocco, was analyzed by gc and gc-ms. altogether 43 components in concentrations of more than 0.2% were identified representing 97.4% of the oil composition. the main constituents were germanicol (12.8%), thunbergol (8.8%), himachalene (7.4%), trans-squalene (6.7%), terpinyl propionate (6.7%), 3,3-dimenthol (6.2%) and cadina-1.4-diene (5.1%). the oils showed strong activity against klebsiella pneumonia, bu ... | 2011 | 22164794 |
[Endogenous endophthalmitis as a first clinical manifestation of Klebsiella sepsis. The importance of an early diagnosis]. | CASE REPORT: A diabetic patient who developed a unilateral uveitis with a chorioretinitis patch in his right eye associated with decreased visual acuity and fever. Endogenous endophthalmitis was suspected and complementary tests were performed, finding hepatic abscesses with Klebsiella isolation in the biopsy. The ocular disorder slowly improved with intravenous therapy and guided percutaneous liver drainage. CONCLUSION: Endogenous Klebsiella endophthalmitis is an uncommon condition with severe ... | 2011 | 22117741 |
High Prevalence of Multidrug-Resistant Nonfermenters in Hospital-acquired Pneumonia in Asia. | Rationale: Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) remain important causes of morbidity and mortality. Increasing antimicrobial resistance has aroused the concern of the failure of antibiotic treatment. Objectives: To determine the distribution of the bacterial isolates of HAP and VAP, their antimicrobial resistance patterns, and impact of discordant antibiotic therapy on clinical outcome in Asian countries Methods: A prospective surveillance study was conduct ... | 2011 | 21920919 |
phylogenetic characterization of bacteria in the gut of house flies (musca domestica l.). | house flies (musca domestica l.) are cosmopolitan, ubiquitous, synanthropic insects that serve as mechanical or biological vectors for various microorganisms. to fully assess the role of house flies in the epidemiology of human diseases, it is essential to understand the diversity of microbiota harbored by natural fly populations. this study aimed to identify the diversity of house fly gut bacteria by both culture-dependent and culture-independent approaches. a total of 102 bacterial strains wer ... | 2011 | 22092755 |
Cortistatin is induced in brain tissue and exerts neuroprotection in a rat model of bacterial meningoencephalitis. | There are fewer reports of brain infection by Klebsiella pneumoniae than there are in other organs, but an increase incidence and morbidity has been noted. We have previously developed a rat model of K. pneumoniae meningoencephalitis. Cortistatin (CST) is a recently discovered neuropeptide with endocrine activities in humans. In this study, we found that brain infection by K. pneumoniae increased endogenous prepro-CST messenger RNA expression, which occurred earlier than did leukocyte infiltrati ... | 2011 | 21940421 |
antimicrobial effect of bee honey in comparison to antibiotics on organisms isolated from infected burns. | despite recent advances in antimicrobial chemotherapy and burn wound management, infection continues to be an important problem in burns. honey is the most famous rediscovered remedy that is used to treat infected wounds and promote healing. the present study aims to evaluate the antimicrobial effect of bee honey on organisms isolated from infected burns in comparison to the antibiotics used in treatment of burn infection, and to evaluate the effects produced when bee honey is added to antibioti ... | 2007 | 21991075 |
trends in nosocomial bloodstream infections in a burn intensive care unit: an eight-year survey. | this study was designed to evaluate the frequency and profile of bloodstream infection (bsi) in a burn intensive care unit (bicu) in tripoli, libya, from 1st january 2000 to 31st december 2007 and to determine the prevalence of different bacteria involved in such infections and their antimicrobial susceptibilities. during the eight-year study period, 995 patients were admitted to the bicu. blood cultures were collected from each septicaemic case and reviewed for age, sex, total body surface area ... | 2010 | 21991204 |
[isolation of an excellent bio-flocculant-producing strain and its application in the treatment of cold-rolling waste oily water]. | an excellent strain (designated as t-3) which produces bio-flocculants was isolated from soil samples, and identified as klebsiella sp. species based on the analysis of morphology, physiology and biochemistry and 16s rdna sequences measurement. the effects of culture conditions such as ph values, temperature, carbon sources and nitrogen sources on bio-flocculants production by t-3 strain were studied. the experiment results show that t-3 strain has better adaptability to carbon sources and nitro ... | 2011 | 22165244 |
differential effect of prior influenza infection on alveolar macrophage phagocytosis of staphylococcus aureus and escherichia coli: involvement of interferon-gamma production. | the influenza a virus is one of the main causes of respiratory infection. although influenza virus infection alone can result in pneumonia, secondary bacterial infection combined with the virus is the major cause of morbidity and mortality. interestingly, while influenza infection increases susceptibility to some bacteria, including streptococcus pneumoniae, staphylococcus aureus (s. aureus), and haemophilus influenzae, other bacteria such as escherichia coli (e. coli) and klebsiella pneumoniae ... | 2011 | 21895747 |
overcoming the rigors of klebsiella pneumoniae. | | 2011 | 21879371 |
engineering genetically encoded nanosensors for real-time in vivo measurements of citrate concentrations. | citrate is an intermediate in catabolic as well as biosynthetic pathways and is an important regulatory molecule in the control of glycolysis and lipid metabolism. mass spectrometric and nmr based metabolomics allow measuring citrate concentrations, but only with limited spatial and temporal resolution. methods are so far lacking to monitor citrate levels in real-time in-vivo. here, we present a series of genetically encoded citrate sensors based on förster resonance energy transfer (fret). we s ... | 2011 | 22164251 |
Fermentation strategies for 1,3-propanediol production from glycerol using a genetically engineered Klebsiella pneumoniae strain to eliminate by-product formation. | We generated a genetically engineered Klebsiella pneumoniae strain (AK-VOT) to eliminate by-product formation during production of 1,3-propanediol (1,3-PD) from glycerol. In the present study, the glycerol-metabolizing properties of the recombinant strain were examined during fermentation in a 5 L bioreactor. As expected, by-product formation was completely absent (except for acetate) when the AK-VOT strain fermented glycerol. However, 1,3-PD productivity was severely reduced owing to a delay in ... | 2011 | 21959580 |
Necrotic intramuscular chloroma with infection: magnetic resonance imaging features. | We recently experienced the case of an intramuscular chloroma with infection in a 7-year-old boy diagnosed with acute myeloid leukemia. Conventional magnetic resonance imaging (MRI) showed that the lesion mimicked an abscess, but diffusion-weighted imaging showed no diffusion restriction. These results suggested that the interior cystic portion was serous. On histopathological findings, a chloroma was diagnosed on the wall of a mass. Culture of the interior fluid revealed that Klebsiella pneumon ... | 2011 | 22009427 |
evolution of surfactant protein-d levels in children with ventilator-associated pneumonia. | rationale: the pathobiology of ventilator-associated pneumonia (vap) in children is poorly understood; investigation has been limited by lack of universally applied diagnostic criteria and reliable biomarkers for this condition. objectives: we evaluated the clinical pulmonary infection score (cpis) in diagnosing vap and prospectively characterized the relationship between surfactant protein-d (sp-d) metabolism and vap. methods: children admitted to an egyptian picu requiring intubation were scre ... | 2011 | 21901856 |
french results of the aresc study: clinical aspects and epidemiology of antimicrobial resistance in female patients with cystitis. implications for empiric therapy. | objective: uncomplicated cystitis is one of the most frequent community infections. we report the french results of the international aresc study on the clinical aspects, epidemiology, and antimicrobial susceptibility of uropathogens. patient and methods: female patients between 18 and 65 years of age, with symptoms of uncomplicated cystitis, were investigated clinically with urinalysis and urine culture. uropathogens were identified and their susceptibility was tested with nine antimicrobials. ... | 2012 | 22264668 |
on the evolution of the sexually transmitted bacteria haemophilus ducreyi and klebsiella granulomatis. | haemophilus ducreyi and klebsiella (calymmatobacterium) granulomatis are sexually transmitted bacteria that cause characteristic, persisting ulceration on external genitals called chancroid and granuloma inguinale, respectively. those ulcers are endemic in developing countries or exist, as does granuloma inguinale, only in some geographic "hot spots."h. ducreyi is placed in the genus haemophilus (family pasteurellacae); however, this phylogenetic position is not obvious. the multiple ways in whi ... | 2011 | 22239475 |
production of 2,3-butanediol from acid hydrolysates of jatropha hulls with klebsiella oxytoca. | jatropha hulls were successfully for the first time used as raw materials for the production of 2,3-butanediol via dilute sulfuric acid hydrolysis and fermentation with klebsiella oxytoca. two-step hydrolysis was used to effectively hydrolyze the hulls at 150°c after pretreatment. in the first-step, hemicellulose was hydrolyzed under mild conditions (0.5h, 1.5% acid) to avoid secondary decomposition. the remained cellulose was further hydrolyzed in the second-step under severer conditions (1h, 4 ... | 2011 | 22230777 |
characterization of carbapenem-nonsusceptible klebsiella pneumoniae bloodstream isolates at a taiwanese hospital: clinical impacts of lowered breakpoints for carbapenems. | this study was conducted in order to characterize carbapenem-nonsusceptible klebsiella pneumoniae isolates and to evaluate the impacts of recently lowered interpretative breakpoints for carbapenems for enterobacteriaceae. among 152 k. pneumoniae bloodstream isolates suspected as ampc or extended-spectrum β-lactamase (esbl) producers, 58 (38.2%) isolates were currently interpreted as nonsusceptible to ertapenem, imipenem, or meropenem, and 42 (72.4%) of them were categorized as carbapenem-suscept ... | 2012 | 22249422 |
significance of perioperative infection in survival of patients with ovarian cancer. | perioperative infectious diseases comprise some of the most common causes of surgical mortality in women with ovarian cancer. this study was aimed to evaluate the significance of perioperative infections in survival of patients with ovarian cancer. | 2012 | 22228425 |
different potency of bacterial antigens, both tlr2 and tlr4 ligands, in stimulating mature mast cells to cysteinyl leukotriene synthesis. | the aim of study was to compare the potency of different bacterial antigens to induce rat mature mast cell to cysteinyl leukotriene (cyslt) generation. we examined toll-like receptor (tlr)2 agonists, i.e. lipoteichoic acid (lta) staphylococcus faecalis, streptococcus pyogenes, bacillus subtilis and staphylococcus aureus, lipoarabinomannan (lam) mycobacterium smegmatis, peptydoglican (pgn) staphylococcus aureus, as well as tlr4 agonists, i.e. lipopolysaccharide (lps) klebsiella pneumoniae, pseudo ... | 2012 | 22233438 |
piperacillin-tazobactam as an initial empirical therapy of bacteremia caused by extended-spectrum β-lactamase-producing escherichia coli and klebsiella pneumoniae. | | 2012 | 22274414 |
prevalence of bacterial pathogens in aseer region, kingdom of saudi arabia: emphasis on antimicrobial susceptibility of staphylococcus aureus. | this short study aims to determine the prevalence of various bacterial pathogens causing infections in the aseer regions, and to also assess the distribution of staphylococcus aureus in relation to different body sites as well as their in vitro antimicrobial susceptibility profile. | 2011 | 22216389 |
etiology of acute, non-malaria, febrile illnesses in jayapura, northeastern papua, indonesia. | abstract. we conducted a prospective, inpatient fever study in malaria-endemic papua, indonesia to determine non-malaria fever etiologies. investigations included malaria blood films, blood culture, paired serologic samples analysis for dengue, japanese encephalitis, leptospirosis, scrub typhus, murine typhus, and spotted fever group rickettsia. during 1997-2000, 226 patients (127 males and 99 females) 1-80 years of age (median age = 25 years) were enrolled. positive blood cultures (n = 34, 15%) ... | 2012 | 22232450 |
antimicrobial resistance of bacterial agents of the upper respiratory tract in south indian population. | the study was aimed at determining bacterial agents of the upper respiratory tract and the susceptibility patterns of isolates to antibiotics. the throat swab samples from 250 patients suspected of upper respiratory tract infection (urti) were obtained from the general medicine outpatient department of a rural health centre of rajah muthiah medical college and hospital (rmmc and h), annamalai university, chidambaram, tamilnadu, india and inoculated in the culture medium. the bacterial infection ... | 2010 | 22247847 |
development of an optimized random amplified polymorphic dna protocol for fingerprinting of klebsiella pneumoniae. | aims: to develop an optimized random amplified polymorphic dna (rapd) protocol for fingerprinting clinical isolates of klebsiella pneumoniae. methods and results: employing factorial design of experiments, repeatable amplification patterns were obtained for 54 nosocomial isolates using 1 μmol 1(-1) primer, 4 mmol 1(-1) mgcl(2) , 0·4 mmol 1(-1) dntps, 2·5 u taq dna polymerase and 90 ng dna template in a total volume of 25 μl. the optimum thermocycling program was: initial denaturation at 94° ... | 2012 | 22220979 |
mitochondrial dna 8993t>g mutation in a child with ornithine transcarbamylase deficiency and leigh syndrome: an unexpected association. | mc, female, is the third child of a nonconsanguineous portuguese couple, born after an uneventful pregnancy and delivery. a positive family history of ornithine transcarbamylase deficiency, associated with the ivs8+1 g>a mutation in the ornithine transcarbamylase gene, prompted prenatal diagnosis with identification of the same mutation in the proband. during an episode of klebsiella pneumoniae sepsis at 1.5 months of age, lactic acidosis and moderate hyperammonemia were noticed. after a short a ... | 2012 | 22241703 |
role of primary bacterial contamination of a pulmonary homograft for ross operation: report of a case and review of the literature. | in a 43-year-old female, ross operation was performed with annular reinforcement of the autograft and a cryo-fixed homograft that proved to be contaminated with enterobacter cloacae and klebsiella pneumoniae at the time of operation. clinical course was unremarkable, perhaps due to effective antibiotic prophylaxis and treatment. in the literature, little is known about intraoperative bacterial contamination and early endocarditis. the authors report what they believe is the second reported case. ... | 2012 | 22215504 |
faecal carriage of extended-spectrum β-lactamase-producing enterobacteriaceae among humans in java, indonesia, in 2001-2002. | objective to characterise commensal escherichia coli and other enterobacteriaceae with reduced susceptibility to cefotaxime that were collected in a large survey carried out among 3995 patients and healthy persons in two urban regions on java, indonesia, in 2001-2002. methods the putative extended-spectrum β-lactamase (esbl)-producing enterobacteriaceae were analysed using double-disk synergy tests, isoelectric focusing, pcr assays, dna sequencing, and pulsed-field gel electrophoresis (pfge). ... | 2012 | 22248076 |
functional analysis of cus operon promoter of klebsiella pneumoniae using e. coli lacz assay. | the transcriptional fusion of reporter lacz gene with cusrs regulatory promoter of cus operon of klebsiella pneumoniae enabled us to analyze the inductive effect of copper on promoter via lacz assay. the stimulus response curve of promoter to a range of copper metal concentrations indicated a normal sigmoidal response profile with apparent hill coefficient 1.0. there was a positive correlation of promoter response to the increasing concentration of copper in the medium. ac(50) value of copper wa ... | 2011 | 22230226 |
klebsiella pneumoniae related community-acquired acute lower respiratory infections in cambodia: clinical characteristics and treatment. | abstract: background: in many asian countries, klebsiella pneumoniae (kp) is the second pathogen responsible for community-acquired pneumonia. yet, very little is known about kp etiology in alri in cambodia, a country that has one of the weakest medical infrastructures in the region. we present here the first clinico-radiological description of kp community-acquired alri in hospitalized cambodian patients. methods: through alri surveillance in two provincial hospitals, kp was isolated from sput ... | 2012 | 22233322 |
phenotypic screening of carbapenemases and associated beta-lactamases in carbapenem-resistant enterobacteriaceae. | dissemination of carbapenem resistance among enterobacteriaceae poses a considerable threat to public health. carbapenemase gene detection by molecular methods is the gold standard but is only available in few laboratories. the aim of this study was to test phenotypic methods for the detection of metallo-β-lactamase (mbl)- or klebsiella pneumoniae carbapenemase (kpc)-producing enterobacteriaceae and associated mechanisms of beta-lactam resistance against a panel of 30 genotypically characterized ... | 2012 | 22259214 |
bronchoscopic findings in children with chronic wet cough. | objectives:protracted bacterial bronchitis is defined as the presence of more than 4 weeks of chronic wet cough that resolves with appropriate antibiotic therapy, in the absence of alternative diagnoses. the diagnosis of protracted bacterial bronchitis is not readily accepted within the pediatric community, however, and data on the incidence of bacterial bronchitis in children are deficient. the objective of this study was to determine the frequency of bacterial bronchitis in children with chron ... | 2012 | 22232311 |
coastal seawater bacteria harbor a large reservoir of plasmid-mediated quinolone resistance determinants in jiaozhou bay, china. | diversity and prevalence of plasmid-mediated quinolone resistance determinants were investigated in environmental bacteria isolated from surface seawater of jiaozhou bay, china. five qnr gene alleles were identified in 34 isolates by pcr amplification, including qnra3 gene in a shewanella algae isolate, qnrb9 gene in a citrobacter freundii isolate, qnrd gene in 22 proteus vulgaris isolates, qnrs1 gene in 1 enterobacter sp. and 4 klebsiella spp. isolates, and qnrs2 gene in 1 pseudomonas sp. and 4 ... | 2012 | 22252223 |
in vitro potential of equine defa1 and ecath1 as alternative antimicrobial drugs in rhodococcosis treatment. | rhodococcus equi, the causal agent of rhodococcosis, is a severe pathogen of foals but also of immunodeficient humans causing bronchopneumonia. the pathogen is often found together with klebsiella pneumoniae or streptococcus zooepidemicus in foals. of great concern is the fact that some r. equi strains are already resistant to commonly used antibiotics. in the present study, we evaluated the in vitro potential of two equine antimicrobial peptides (amps), ecath1 and defa1, as new drugs against r. ... | 2012 | 22232283 |
study of plasmid-mediated extended-spectrum β-lactamase-producing strains of enterobacteriaceae, isolated from diabetic foot infections in a north indian tertiary-care hospital. | abstract aim: this study evaluated the incidence and factors responsible for plasmid-mediated extended-spectrum β-lactamase (esbl) infection among patients with diabetic foot ulcer (dfu). subjects and methods: a prospective study was conducted on 162 dfu inpatients treated in a multidisciplinary-based diabetes and endocrinology center at jawaharlal nehru medical college of aligarh muslim university, aligarh, india, during the period of december 2008-march 2011. detailed history and patient's ... | 2012 | 22225456 |
characterization of a single-stranded dna-binding protein from klebsiella pneumoniae: mutation at either arg73 or ser76 causes a less cooperative complex on dna. | single-stranded dna-binding protein (ssb) plays an important role in dna metabolism, such as in processes like dna replication, repair and recombination, and is essential for cell survival. here, we characterized the ssdna-binding properties of klebsiella pneumoniae ssb (kpssb) by using fluorescence-quenching measurements, electrophoretic mobility shift analysis (emsa) and site-directed mutagenesis. analysis of purified kpssb by gel-filtration chromatography showed a stable tetramer in solution. ... | 2012 | 22244199 |
a case of oxa-48 carbapenemase-producing klebsiella pneumoniae in a patient transferred to slovenia from libya, november 2011. | | 2011 | 22221496 |
the role of nutrients in the biodegradation of 2,4,6-trinitrotoluene in liquid and soil. | the widely used explosive 2,4,6-trinitrotoluene (tnt) has residues that are potentially explosive, toxic, and mutagenic. tnt and other explosives can be degraded by microorganisms; however, biostimulation is needed for process efficiency. to investigate the effectiveness of using biostimulation to degrade tnt, we added varying concentrations of a nutrient amendment consisting of inorganic salts, plant extracts, and molasses to soil and liquid media. for the inoculum we used a consortium of bacte ... | 2012 | 22245864 |
chemical compositions of the essential oils of aerial parts of chamaemelum mixtum (l.) alloni. | the chemical compositions of the aerial parts essential oils of chamaemelum mixtum (l.) alloni from corsica and sardinia were investigated employing gas chromatography and gas chromatography/mass spectrometry. the structure of (z)-heptadeca-9,16-dien-7-one, a natural compound not previously described, was elucidated by gas chromatography/mass spectrometry (electron impact and chemical ionization) and one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy. the variation in ch ... | 2012 | 22225420 |
antimicrobial activity of ulopterol isolated from toddalia asiatica (l.) lam.: a traditional medicinal plant. | aim of the study: the leaves of toddalia asiatica (l.) lam. (rutaceae) are widely used in folk medicine in india to treat various ailments. in our earlier communication we have reported the antimicrobial study on the various extracts of the leaves and the isolation and identification of flindersine, a quinolone alkaloid as the major active principle. in the present study, we report the antibacterial and antifungal activities of ulopterol, a coumarin isolated as another major active antimicrobial ... | 2012 | 22265751 |
prevalence of antibiotic resistance in fecal flora of patients undergoing transrectal ultrasound-guided prostate biopsy in thailand. | objective: the objective of this study was to determine the prevalence of antibiotic resistance in fecal flora of patients undergoing transrectal ultrasound-guided needle biopsy of the prostate (trusb) and the factors associated with such antibiotic resistance. methods: a prospective study of patients undergoing trusb was conducted. rectal swabs were performed and sent for cultures and antibiotic susceptibility testing before trusb. clinical characteristics were determined. results: 287 gram-neg ... | 2012 | 22269856 |
klebsiella pneumoniae st258 producing kpc-3 identified in italy carries novel plasmids and ompk36/ompk35 porin variants. | a carbapenemase resistant klebsiella pneumoniae strain, clone st258 producing kpc-3 was fully characterized. the entire plasmid content was investigated, identifying plasmids of the incfii(k) (two of them similar to pkpqil and pkpn3, respectively), incx and cole types, encoding for a formidable set of resistance genes against toxic compounds, metals and antimicrobial drugs and a novel iron(iii) uptake system. | 2012 | 22252815 |
nosocomial clustering of ndm-1-producing klebsiella pneumoniae sequence type 340 in four patients at a korean tertiary care hospital. | in november 2010, ndm-1-producing klebsiella pneumoniae (ndmkp) was identified from four patients stayed for 21 to 205 days in a tertiary care hospital with no travelling history abroad, which was first time in korea. all were st340 and had nearly identical xbai-pfge patterns. the bla(ndm-1)-carrying plasmids were inc/rep n group with a variable size of 50-200 kb. these findings suggest that ndmkp had already been introduced into korea before this clustering found. | 2012 | 22259206 |
isolation and characterization of lipase-producing bacteria in the intestine of the silkworm, bombyx mori, reared on different forage. | abstract the silkworm, bombyx mori l. (lepidoptera: bombycidae), an oligophagous insect that mainly feeds on mulberry leaves, is susceptible to entomopathogen infection when reared with tricuspid cudrania leaves. a total of 56 dominant bacterial strains, classified into 12 phylotypes based on bacteriological properties and analysis of 16s rrna genes, were isolated from the intestine of the fourth and fifth instar silkworm larvae. ten and seven phylotypes exist in the intestine of the silkworm ... | 2011 | 22243438 |
a randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation. | community-acquired pneumonia (cap) is a serious infection requiring hospitalisation in 20% of cases. the novel cephalosporin ceftobiprole has microbiological activity against the major bacterial pathogens causing cap, including streptococcus pneumoniae, haemophilus influenzae and klebsiella pneumoniae, as well as against staphylococcus aureus, including meticillin-resistant s. aureus (mrsa). this was a multicentre, double-blind study in which 706 patients with cap severe enough to require hospit ... | 2012 | 22230331 |
antimicrobial susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in south african hospitals (smart study 2004-2009): impact of the new carbapenem breakpoints. | abstract background: the study for monitoring antimicrobial resistance trends (smart) follows trends in resistance among aerobic and facultative anaerobic gram-negative bacilli (gnb) isolated from complicated intra-abdominal infections (ciais) in patients around the world. methods: during 2004-2009, three centralized clinical microbiology laboratories serving 59 private hospitals in three large south african cities collected 1,218 gnb from complicated intra-abdominal infections (ciais) and t ... | 2012 | 22220506 |
one-day point prevalence of emerging bacterial pathogens in four secondary and five tertiary care german hospitals - results from a pilot study of the german society for hospital hygiene (deutsche gesellschaft für krankenhaushygiene, dgkh). | objective: data on the prevalence of emerging bacterial pathogens like extended-spectrum-lactamase-building (esbl) gram negative organisms, multiresistant pseudomonas and acinetobacter species or toxin-building clostridium difficile in german hospitals are sparse. to provide data for different regions in germany, a one-day point prevalence study with five tertiary care hospitals and four secondary care hospitals was conducted on the 10(th) of february 2010.method: for participating hospitals, th ... | 2011 | 22242101 |
prevalence of plasmid mediated bla(tem-1) and bla(ctx-m-15) type extended spectrum beta-lactamases in patients with sepsis. | to characterize the bacterial pathogens in patients having gram negative septicaemia. further, to evaluate the antimicrobial resistance and underlying molecular mechanisms in these strains. | 2012 | 22221749 |
seroepidemiology of klebsiella pneumoniae colonizing the intestinal tract of healthy chinese and overseas chinese adults in asian countries. | abstract: background: capsular serotypes k1 and k2 of klebsiella pneumoniae are thought to the major virulence determinants responsible for liver abscess. the intestine is one of the major reservoirs of k. pneumoniae, and epidemiological studies have suggested that the majority of k. pneumoniae infections are preceded by colonization of the gastrointestinal tract. the possibility of fecal-oral transmission in liver abscess has been raised on the basis of molecular typing of isolates. data on th ... | 2012 | 22260182 |
characterization of a novel klebsiella pneumoniae sequence type 476 carrying both bla (kpc-2) and bla (imp-4). | carbapenemase-producing klebsiella pneumoniae has recently spread rapidly throughout china. in this study, we characterized a carbapenem-resistant k. pneumoniae isolate that produced both kpc-2 and imp-4 type carbapenemases. a clinical isolate of k. pneumoniae, resistant to both meropenem and imipenem, was recovered from a urine sample. antibiotic susceptibility was determined using the broth microdilution method and etest (biomérieux, france). pulsed-field gel electrophoresis and multilocus seq ... | 2012 | 22271301 |
klebsiella pneumoniae septic wrist arthritis successfully treated with ertapenem and levofloxacin. | | 2011 | 22233826 |
bla (kpc) and rmtb on a single plasmid in enterobacter amnigenus and klebsiella pneumoniae isolates from the same patient. | enterobacter amnigenus (ea76) and klebsiella pneumoniae (kp76) isolates with multidrug-resistant (mdr) patterns were identified from the same patient in the neurosurgery department of our hospital. an outbreak of mdr k. pneumoniae had also occurred in this department. to characterize the resistance mechanism and molecular epidemiology of these isolates, sequential experiments including antimicrobial susceptibility testing, polymerase chain reaction (pcr), plasmid analysis, pulsed field gel elect ... | 2012 | 22237458 |
synthesis and anti-microbial screening of novel schiff bases of 3-amino-2-methyl quinazolin 4-(3h)-one. | in the present study, novel schiff bases were synthesized by condensation of 3-amino-2-methyl quinazolin-4-(3h)-ones with different aromatic aldehydes. the 3-amino-2-methyl quinazolin-4-(3h)-one was synthesized from anthranilic acid via the 2-methyl benzoxazin-4-one. the chemical structures of the synthesized compounds were confirmed by means of infrared (ir), (1)h-nmr, (13)c-nmr, mass spectral, and elemental analysis. these compounds were screened for anti-bacterial (staphylococcus aureus atcc ... | 2010 | 22247864 |
chemometric modeling and two-dimensional fluorescence analysis of bioprocess with a new strain of klebsiella pneumoniae to convert residual glycerol into 1,3-propanediol. | the goal of this study was to show that the metabolism of klebsiella pneumoniae under different aeration strategies could be monitored and predicted by the application of chemometric models and fluorescence spectroscopy. multi-wavelength fluorescence was applied to the on-line monitoring of process parameters for k. pneumoniae cultivations. differences observed in spectra collected under aerobiosis and anaerobiosis can be explained by the different metabolic states of the ce ... | 2012 | 22252443 |