[a severe intraoperative complication of cholecystectomy--massive hemorrhage and hemobilia]. | | 1992 | 1395883 |
nosocomial bacterial infections among children with severe protein energy malnutrition. | the incidence of hospital acquired acute bacterial infections among 164 severely malnourished children admitted to the paediatric wards at the muhimbili medical centre in dar es salaam were studied. on admission, ninety two per cent of the patients had at least one form of bacterial infection. during the subsequent two weeks hospital stay, 49% of the patients acquired a new infection. septicaemia and urinary tract infection (uti) were the commonest infections. staphylococcus aureus was the commo ... | 1992 | 1396209 |
antibacterial activity of the investigational oral and parenteral cephalosporin bk-218. | bk-218 is a novel cephalosporin with a dual route of administration and spectrum of activity most similar to that of second-generation cephalosporins. bk-218 was active against streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis but strains resistant to penicillins had higher mics. bk-218 had greater activity (8-fold) than cefuroxime or cefaclor against oxacillin-susceptible staphylococcus spp. moderate bk-218 activity was observed against neisseria gonorrhoeae and commonl ... | 1992 | 1396735 |
isolation of klebsiella terrigena from clinical specimens. | in a three-year survey conducted from 1988 to 1990 klebsiella isolates from human clinical specimens were subjected to additional tests to identify any klebsiella terrigena strains. ten strains of klebsiella terrigena (0.4%) were found among 2355 indole-negative klebsiella isolates. most of the isolates were recovered from the respiratory tract. in the api20ec system almost exclusively biotypes no. 1777771 and 1777671 were observed. serotyping revealed capsule types k2, k5 and k18 in two strains ... | 1992 | 1396756 |
comparative in vitro activity and beta-lactamase stability of ru29246, the active metabolite of hr916b. | hr 916b is a new orally absorbed cephalosporin. in tests its active metabolite, ru29246, inhibited streptococcus pyogenes, streptococcus agalactiae and streptococcus pneumoniae at less than or equal to 0.12 micrograms/ml, which is similar to the antibacterial activity of cefuroxime, and was more active than cefaclor. it was also more active (mic 2 micrograms/ml) than cefixime, cefuroxime, cefaclor and cefotaxime against staphylococci. ru29246 inhibited escherichia coli, klebsiella pneumoniae, ci ... | 1992 | 1396779 |
a serological test for granuloma inguinale. | an indirect immunofluorescence technique applied to paraffin embedded tissue sections of lesions containing donovan bodies was evaluated as a serological test for the diagnosis of granuloma inguinale. | 1992 | 1398665 |
citrobacter sepsis in infants. | a study of blood cultures from 320 cases of neonatal sepsis showed 136 (42.5%) to be positive for bacterial growth; of these 82 (60.29%) isolates being gram negative bacilli. citrobacter was the commonest gram negative bacilli isolated. other commonly isolated gram negative organisms were pseudomonas, klebsiella, salmonella typhimurium, acinetobacter and escherichia coli. antibiotics susceptibility pattern revealed the isolates to be resistant to commonly used antibiotics. | 1992 | 1398863 |
roles of peripheral leukocytes and tissue macrophages in antibacterial resistance induced by free or liposome-encapsulated muramyl tripeptide phosphatidylethanolamide. | administration of free muramyl tripeptide phosphatidylethanolamide (mtppe) or liposome-encapsulated mtppe (le-mtppe) in a twofold-lower dose at 24 h before bacterial inoculation resulted in clearance of intravenously inoculated klebsiella pneumoniae by tissue macrophages, whereas in control mice, bacteria were not effectively cleared from the blood. in addition, mtppe and le-mtppe led to increased numbers of leukocytes in the blood, which could compensate for the leukopenia in mice resulting fro ... | 1992 | 1399000 |
comparative study of klebsiella oxytoca and klebsiella pneumoniae isolates in a general hospital. | | 1992 | 1399511 |
evaluation of four membrane filter media in anaerobic-mf recovery of faecal coliforms from freshwater in nigeria. | macconkey (mc), membrane lauryl sulphate (mis), membrane faecal coliform amended with rosolic acid (mfc + r) and without the acid (mfc - r) were evaluated in the anaerobic membrane filtration (anaerobic-mf) recovery of faecal coliform populations (fcs), genera and faecal coliform positive (fc-positive) strains isolated from various sources of freshwater, i.e., rivers, rural wells, unchlorinated distributive supplies and hand pumps. mean counts (x 10(2)/100 ml) of presumptive (typical) fcs varied ... | 1992 | 1399909 |
molybdenum cofactor (chlorate-resistant) mutants of klebsiella pneumoniae m5al can use hypoxanthine as the sole nitrogen source. | selection for chlorate resistance yields mol (formerly chl) mutants with defects in molybdenum cofactor synthesis. complementation and genetic mapping analyses indicated that the klebsiella pneumoniae mol genes are functionally homologous to those of escherichia coli and occupy analogous genetic map positions. hypoxanthine utilization in other organisms requires molybdenum cofactor as a component of xanthine dehydrogenase, and thus most chlorate-resistant mutants cannot use hypoxanthine as a sol ... | 1992 | 1400180 |
chemolithoautotrophic assimilation of dinitrogen by streptomyces thermoautotrophicus ubt1: identification of an unusual n2-fixing system. | streptomyces thermoautotrophicus ubt1, which was isolated previously from a burning charcoal pile, was shown to utilize n2 as a sole nitrogen source when growing chemolithoautotrophically with co or h2 plus co2 under aerobic conditions at 65 degrees c. doubling times under diazotrophic conditions were 10 h. s. thermoautotrophicus is a new co- or h2-oxidizing, obligately chemolithoautotrophic, thermophilic, free-living, aerobic, n2-fixing streptomycete. its ability to fix n2 was also evident from ... | 1992 | 1400234 |
the pseudomonas syringae pv. syringae 61 hrph product, an envelope protein required for elicitation of the hypersensitive response in plants. | pseudomonas syringae pv. syringae 61 contains a 25-kb cluster of hrp genes that are required for elicitation of the hypersensitive response (hr) in tobacco. tnphoa mutagenesis of cosmid phir11, which contains the hrp cluster, revealed two genes encoding exported or inner-membrane-spanning proteins (h.-c. huang, s. w. hutcheson, and a. collmer, mol. plant-microbe interact. 4:469-476, 1991). the gene in complementation group x, designated hrph, was subcloned on a 3.1-kb sali fragment into pcpp30, ... | 1992 | 1400238 |
site-directed mutagenesis of the active site cysteine in klebsiella aerogenes urease. | cysteine 319 in the large subunit of klebsiella aerogenes urease was identified as an essential catalytic residue based on chemical modification studies (todd, m.j., and hausinger, r.p. (1991) j. biol. chem. 266, 24327-24331). through site-directed mutagenesis, this cysteine has been changed independently to alanine, serine, aspartate, and tyrosine. none of these mutations (c319a, c319s, c319d, and c319y, respectively) affected the size or level of synthesis of the urease subunits as monitored b ... | 1992 | 1400317 |
nitrilase from rhodococcus rhodochrous j1. sequencing and overexpression of the gene and identification of an essential cysteine residue. | the amino acid sequences of the nh2 terminus and internal peptide fragments of a rhodococcus rhodochrous j1 nitrilase were determined to prepare synthetic oligonucleotides as primers for the polymerase chain reaction. a 750-base dna fragment thus amplified was used as the probe to clone a 5.4-kilobase psti fragment coding for the whole nitrilase. the nitrilase gene modified in the sequence upstream from the presumed atg start codon was expressed to approximately 50% of the total soluble protein ... | 1992 | 1400390 |
community-acquired bacteremia in the elderly: a prospective study of 121 cases. | to describe community-acquired bacteremia in the elderly and correlate clinical and laboratory findings with outcome. | 1992 | 1401689 |
necrotizing fasciitis of the neck and chest. report of a case. | a case is presented of necrotizing fasciitis of the neck and chest characterized by rapid progressive necrosis of subcutaneous tissue, fascia and skin. the diagnosis and management is discussed. | 1992 | 1402054 |
changing patterns of blood culture isolates from patients with acute leukemia: a review of twenty years' experience. | during the 20-year period, 1972-1991, 286 episodes of bacteremia occurred in 200 (45%) of 445 patients with acute leukemia in a hematology ward, giving an incidence of 482 episodes per 1,000 hospital admissions. the frequency of bacteremia was almost unchanged throughout the study period. the frequency of gram-negative bacilli decreased significantly, however, from 81% of all the isolates for the first half of the study period to 50% for the latter half. despite the common use of ceftazidime and ... | 1992 | 1402104 |
[role of capsular polysaccharide and lipopolysaccharide of klebsiella pneumoniae in experimental mice pneumonia model]. | in this study, role of capsular polysaccharide (cps) and lipopolysaccharide (lps) of klebsiella pneumoniae was investigated in experimental mice pneumonia model. inoculation with k. pneumoniae mucoid strain dt-s into mice lung induced expansive, voluminous lethal pneumonia characterized with thickening of the alveolar septa caused by infiltration of inflammatory cell and packing of bacteria within alveolar spaces. on the other hand, mice lung inoculated with k. pneumoniae dt-x, which was non-muc ... | 1992 | 1402109 |
biological activities and chemical composition of a cytotoxin of klebsiella oxytoca. | a low-molecular-mass cytotoxin produced by klebsiella oxytoca isolated previously from patients with antibiotic-associated haemorrhagic enterocolitis was purified, and its biological and chemical properties were elucidated. the toxin inhibited the syntheses of dna and rna by hep-2 cells dose-dependently, whereas protein synthesis was only slightly inhibited, as measured by the incorporation of radioactive precursors. when synchronously cultured hep-2 cells were examined in the presence of cytoto ... | 1992 | 1402792 |
role of integration host factor in stimulating transcription from the sigma 54-dependent nifh promoter. | in a wide variety of nitrogen-fixing organisms among the purple bacteria (large division of gram-negative bacteria) the nitrogen fixation (nif) operons are transcribed by an alternative holoenzyme form of rna polymerase, sigma 54-holoenzyme. transcription depends on the activator protein nifa (nitrogen fixation protein a), which catalyzes isomerization of closed complexes between this polymerase and a promoter to transcriptionally productive open complexes. nifa-mediated activation of transcript ... | 1992 | 1404379 |
preliminary crystallographic studies of urease from jack bean and from klebsiella aerogenes. | ureases from both jack bean (canavalia ensiformis) seeds and klebsiella aerogenes have been crystallized by the hanging drop method. the plant-derived urease crystals are regular octahedra analogous to those obtained by sumner. preliminary x-ray diffraction studies show that the crystals belong to the cubic space group f4(1)32, with a = 364 a, and appear to contain one or two subunits in the asymmetric unit. using a synchrotron source, the crystals diffract to near 3.5 a resolution. crystals of ... | 1992 | 1404395 |
[clinical significance of respiratory infections associated with lung cancer patients]. | an attempt was made to interpret the clinical significance of secondary infections associated with lung cancer. the incidence of secondary infections was 51.4% in 214 in-patients with lung cancer in our institution in 1988 and 1989, and almost all of them had respiratory infections caused by commonly encountered bacteria. the incidence of infection was high in lung cancer of cell types other than adenocarcinoma, and in those with hypoalbuminemia, impaired cellular immunity and obstruction of the ... | 1992 | 1405100 |
optimal method for culturing vascular prosthetic grafts. | vascular prosthetic infection may be underrecognized when identified by standard culture techniques. improved microbiologic methodology may enhance detection of bacteria in prosthetic graft specimens, and thus may alter clinical decisions. quantitative culture techniques were employed to compare three methods of enhancing bacterial recovery from dacron graft cylinders seeded with commonly encountered bacterial pathogens. methods included: (1) ultrasonic bath treatment, (2) direct ultrasonic disr ... | 1992 | 1405618 |
[antibiotic prevention and therapy of infectious complications in ercp]. | endoscopic retrograde cholangiopancreatography (ercp) may be complicated by bacteremia, cholangitis, or biliary sepsis. bacteremia during ercp implies a potential risk of endocarditis in patients with valvular prostheses or a previous history of infectious endocarditis. for these patients antibiotic prophylaxis prior to ercp is recommended. cholangitis or biliary sepsis may develop after ercp in patients with obstructed bile ducts. in these patients antibiotics should be administered until adequ ... | 1992 | 1406012 |
alcohol dehydrogenase mediated acetaldehyde production by helicobacter pylori--a possible mechanism behind gastric injury. | two standard helicobacter pylori strains showed significant cytosolic alcohol dehydrogenase activity and produced considerable amounts of acetaldehyde when incubated with an ethanol containing solution in vitro. the alcohol dehydrogenase activity of the helicobacter pylori strains was almost as high as that found in klebsiella pneumoniae and far greater than that in escherichia coli or campylobacter jejuni. the amount of acetaldehyde produced by cytosol prepared from helicobacter pylori exceeded ... | 1992 | 1406052 |
isolation and characterization of the aada aminoglycoside-resistance gene from salmonella choleraesuis. | the streptomycin- and spectinomycin-resistance gene of salmonella choleraesuis was cloned and its nucleotide sequence determined. the gene is 789 bases long, encoding a protein of a predicted size of 29,353 da. the gene product inactivated streptomycin and spectinomycin by an adenylation modification. it is homologous (c. 40% total identity) to streptomycin adenylyltransferase, a 3'(9)-o-nucleotidyltransferase (aad(3')(9)), which is encoded by the aada gene in escherichia coli, agrobacterium tum ... | 1992 | 1406282 |
adhesion of bacteria on pectin casted films. | pectin and non-pectin degrading bacteria were tested for their ability to adhere to a film casted of low methoxylated pectin (polygalacturonic acid). klebsiella oxytoca and a newly isolated strain of escherichia coli adhered to the film, whereas only k. oxytoca was able to utilize pectin as a sole carbon source. other e. coli strains, containing plasmids with pectinolytic enzymes, did not adhere to the solid pectin film. therefore, the ability of the bacteria to adhere to the films was not corre ... | 1992 | 1406337 |
bactericidal activities of rat defensins and synthetic rabbit defensins on staphylococci, klebsiella pneumoniae (chedid, 277, and 8n3), pseudomonas aeruginosa (mucoid and nonmucoid strains), salmonella typhimurium (ra, rc, rd, and re of lps mutants) and escherichia coli. | rat defensins were purified and tested for in vitro bactericidal assay against gram-positive and gram-negative bacteria. staphylococcus aureus (209p, cowan i, smith diffuse and smith compact) were resistant to defensins, whereas staphylococcus epidermidis, staphylococcus saprophyticus, micrococcus lysodeikticus and bacillus subtilis were less sensitive. gram-negative bacteria, such as pseudomonas aeruginosa (mucoid and k) and klebsiella pneumoniae (chedid, 277, and 8n3 which were heavily capsula ... | 1992 | 1406365 |
ammonia regulation of the rhizobium meliloti nitrogenase structural and regulatory genes under free-living conditions: involvement of the fixl gene product? | the expression under microaerobic conditions of the rhizobium meliloti nifa and consequently the nifhdk genes was found to be negatively regulated by ammonia and nitrate. assimilation of the ammonia to glutamate and glutamine is not required for this regulation to occur. this indicates that ammonia itself, and not a product of its metabolism, may be regulating nif expression. unlike the situation in klebsiella pneumoniae, ntrc is apparently not involved in mediating the ammonia effect on nifa ex ... | 1992 | 1406587 |
gram-negative enteric bacteria in the oral cavity of leukemia patients. | we examined changes in the bacterial flora in hospitalized patients with leukemia. this study placed special emphasis on enteric microorganisms and their relation to the general status of the patient. one hundred thirty bacterial cultures from 16 leukemia patients and 16 control subjects, were obtained. the organisms were isolated on macconkey agar and identified by the api-20e system. enteric microorganisms were isolated from 62.2% of the leukemia patients as compared with 28% from the control ... | 1992 | 1408020 |
evaluation of immunomodulating effects of inhaled bacterial polyribosomal-klebsiella pneumoniae proteoglycans complex on bronchoalveolar immune system in chronic bronchitis. | | 1992 | 1409309 |
[isolated dissecting aneurysm of the superior mesenteric artery. dysplasia, a rare cause of mesenteric ischemia. report of a case]. | we report a case of successful surgical revascularization of the superior mesenteric artery in a patient presenting with intestinal ischaemia due to fibrodysplasia. this is a rare pathology, with 5 cases operated in our institution and only 16 cases reported in the literature. angiography may show other sites of arterial dysplasia. in such cases, success depends on early surgical revascularization. | 1992 | 1409464 |
anaerobic microflora associated with the pars oesophagea of the pig. | in healthy pigs aged one to 35 days significant populations of microorganisms (5.5 to 6.9 log10 viable count cm-2 of the tissue) were found, by strict anaerobic techniques, to adhere to the pars oesophagea. the genera of anaerobes which were isolated included actinomyces, bifidobacterium, clostridium, lactobacillus, peptostreptococcus, streptococcus and veillonella and facultative anaerobes included escherichia, klebsiella, staphylococcus, streptococcus and yeasts. the microbial population adher ... | 1992 | 1410807 |
[decrease in general health status, febrile state and sinusitis in renal insufficiency]. | a 59-year old man, dialysed for 9 years because of chronic renal failure of unknown etiology, was also suffering from a hypertensive cardiopathy and anemia. he has received more than 70 units of blood over the past few years. an elevated blood aluminium level prompted treatment with desferrioxamine for 3 years. following episodes of melena, an intestinal-wall lesion, located 8 cm above the ileo-caecal valve was discovered. blood serotonin levels were elevated; biopsy of the liver revealed tumor ... | 1992 | 1411400 |
urinary tract infection in acute spinal cord injury. | preservation of renal function and prevention of recurrent urinary tract infections is the ultimate goal of any method of neurogenic bladder management in spinal cord injury patients. method--the hospital courses of fifty such patients admitted to our rehabilitation department from august 1989 to august 1990 were studied according to age, gender, spinal cord injury level, method of bladder drainage on admission and upon discharge, type of urinary tract infections and results of bladder managemen ... | 1992 | 1411664 |
[bacteriological examination of bronchial aspirates obtained via fiberoptic bronchoscopy]. | we present the bacteriological findings in 329 aspirates from fiberoptic bronchoscopy. quantitative cultures were not performed. 92 of the patients had radiologically confirmed pneumonia, 58 possibly had infectious bronchitis or pneumonia which was not verified radiologically, 154 had other pulmonary diseases and 25 had no verified pulmonary disease. 13% of aspirates contained no bacterial isolates and 33% revealed growth of multiple bacteria, classified as "normal pharyngeal flora". among the 5 ... | 1992 | 1412305 |
determination of the antiinfectious activity of ru 41740 (biostim) as an example of an immunomodulator. | evaluation of the anti-infectious activity of an immunomodulator performed either in vitro or in vivo in animals as in humans must answer three questions: what are the targets? what models should be used to study the mechanism of action? what methodology should be selected for the assessment of therapeutic benefit? in the case of ru 41470 (biostim), an immunomodulator with a known structure and of biological origin affects immunocompetent cells and two essential mediators: ii1 and csf. because o ... | 1992 | 1414591 |
therapeutic and prophylactic effects of romurtide against experimental animal infections. | | 1992 | 1414593 |
clinical comments on management of urosepsis in a general urological department. | over a period of 6 years 192 cases of urosepsis have been recorded and managed in our urological department. in almost all cases (97%) the primary focus of infection was the urinary tract and the responsible microorganisms were gram-negative rods, in order enterobacter, b. proteus, e. coli, klebsiella and others. clinical features were dominated by symptoms related to failure or insufficiency of end organs (fever, hypotension, oliguria, mental disorders, respiratory distress etc.). bacteremia wa ... | 1992 | 1414720 |
rhinoscleroma and rhinosporidiosis. | for north american otolaryngologists, rhinoscleroma and rhinosporidiosis are moving more into the differential diagnosis of chronic inflammatory diseases of the upper airway, particularly the nasal cavity. this change is occasioned by the influx of immigrants from parts of the world to which the diseases are endemic. diagnosis is established by identification of the causal organisms, the readily seen rhinosporidium seeberi for rhinosporidiosis and the more elusive klebsiella rhinoscleromatis for ... | 1992 | 1416645 |
community acquired urinary tract infections in singapore: a microbiological study. | we studied 214 patients with culture proven community acquired infections. a total of 219 organisms were isolated, of which 68.2% were escherichia coli, 10.1% klebsiella sp and 5.5% proteus mirabilis. gram positive cocci accounted for 10.5% of organisms isolated. the majority of organisms isolated were sensitive to nalidixic acid (81.1%), nitrofurantoin (80.7%), cephalexin (74.7%) and trimethoprim-sulphamethoxazole (65.0%). resistance to ampicillin was common (49.8%), as such the use of ampicill ... | 1992 | 1416785 |
resistance to cefotaxime and seven other beta-lactams in members of the family enterobacteriaceae: a 3-year survey in france. | during the second quarter each of 1988, 1989, and 1990, a french collaborative study group, including 12 university hospital laboratories, surveyed the resistance to beta-lactams of clinical isolates from hospitalized patients: consecutively, 10,641, 10,692, and 9,382 isolates were tested. the distribution of bacterial species over time was similar in each laboratory. the susceptibilities of microorganisms to amoxicillin, ticarcillin, cephalothin, cefoxitin, cefotaxime (ctx), ceftazidime (caz), ... | 1992 | 1416850 |
in vitro activity of mc-352, a new 16-membered macrolide. | the in vitro activity of mc-352, 3,4'-dideoxy-5-o-mycaminosyltylonolide, was compared with those of erythromycin, clarithromycin, and rokitamycin. the mc-352 mic90 (mic for 90% of isolates) for erythromycin-susceptible staphylococcus aureus and staphylococcus epidermidis was less than or equal to 1 microgram/ml, similar to those of the other agents. the mc-352 mic50 for erythromycin-resistant s. aureus was 2 micrograms/ml, similar to that of rokitamycin. the mc-352 mic90 (0.12 micrograms/ml) for ... | 1992 | 1416853 |
in vitro activities of streptomycin and 11 oral antimicrobial agents against clinical isolates of klebsiella rhinoscleromatis. | we tested in vitro the activities of streptomycin and tetracycline--antibiotics that have long been used to treat rhinoscleroma--as well as several newer oral agents by using 23 isolates of the causative organism klebsiella rhinoscleromatis. all isolates were inhibited by clinically achievable concentrations of trimethoprim-sulfamethoxazole, amoxicillin-clavulanate, chloramphenicol, ciprofloxacin, cephalexin, cefuroxime, and cefpodoxime. | 1992 | 1416867 |
nucleotide sequences of caz-2, caz-6, and caz-7 beta-lactamase genes. | caz-2, caz-6, and caz-7 are plasmid-mediated beta-lactamases that are markedly active against ceftazidime. the corresponding structural genes were amplified by the polymerase chain reaction. nucleotide sequences were determined by direct sequencing of the amplified products. analysis of the nucleotide and the deduced amino acid sequences showed that caz-2, caz-6, and caz-7 are derived from tem-2 by three, four, and two amino acid substitutions, respectively. all these substitutions are located a ... | 1992 | 1416873 |
detection of extended-spectrum beta-lactamases in members of the family enterobacteriaceae: comparison of the double-disk and three-dimensional tests. | the three-dimensional and clavulanate double-disk potentiation tests were compared as procedures for the detection of extended-spectrum beta-lactamase production in 32 strains of escherichia coli and klebsiella pneumoniae, 31 of which produced tem-1, tem-2, tem-3, tem-4, tem-5, tem-7, tem-8, tem-9, tem-10, tem-12, tem-101, shv-1, shv-2, shv-3, shv-4, shv-5, caz-2, mir-1, or an unidentified extended-spectrum beta-lactamase with a pi of 5.95, with some strains producing multiple beta-lactamases. t ... | 1992 | 1416878 |
in vitro and in vivo antibacterial activities of e1077, a novel parenteral cephalosporin with a broad antibacterial spectrum. | e1077 is a new injectable cephalosporin with a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria, including staphylococci and pseudomonas aeruginosa. the in vitro activities of e1077 against clinical isolates of methicillin-susceptible staphylococcus aureus (mic of e1077 for 90% of the strains tested [mic90], 0.78 microgram/ml) and methicillin-resistant s. aureus (mic90, 50 micrograms/ml) were similar to those of cefpirome and flomoxef. against enterococcu ... | 1992 | 1416879 |
outbreak of ceftazidime resistance due to a novel extended-spectrum beta-lactamase in isolates from cancer patients. | ceftazidime is widely used in the therapy of infectious complications in neutropenic patients. we studied an outbreak of ceftazidime-resistant gram-negative bacillary infections in pediatric cancer patients receiving empirical ceftazidime therapy for neutropenic fever. fourteen isolates (12 klebsiella pneumoniae and 2 escherichia coli) from 13 patients were studied. specimens were obtained from multiple clinical sites including blood, urine, throat, and lung. the organisms were resistant to ceft ... | 1992 | 1416892 |
[amikacin resistance of clinical strains of enterobacteriaceae and pseudomonas]. | amikacin resistance was studied in 380 bacterial strains of enterobacter, klebsiella, serratia, pseudomonas and e. coli isolated in clinics of the moscow region. it was shown that 69 isolates were resistant to amikacin. plasmid dna was detected in 10 amikacin resistant isolates. three of them belonging to klebsiella and 3 belonging to e. coli contained plasmids controlling resistance to amikacin. the plasmids isolated from the strains of klebsiella determined as well resistance to kanamycin and ... | 1992 | 1417311 |
polyphenols from bulgarian medicinal plants with anti-infectious activity. | three bulgarian medicinal plants--geranium macrorrhizum l. and g. sanguineum l. (geraniaceae), and epilobium hirsutum l. (onagraceae) were analyzed phytochemically. different polyphenols like flavonoids and tannis have been found to be principal constituents of the plants. a series of water or alcohol extracts was obtained, and their anti-infectious activity was tested. a significant inhibitory effect of water-alcohol extract and of four fractions from the polyphenolic mixture of e. hirsutum on ... | 1992 | 1417697 |
a visual method for rapid screening of xylose-fermenting ethanolic strains of klebsiella pneumoniae. | a simple and rapid screening method for selecting hyper-ethanolic strains of klebsiella pneumoniae is described. the method involves a novel biological screening marker, namely, the yeast candida ethanothermophilum. the screening marker was seeded on an agar plate to the surface of which agar blocks, each containing a colony of k. pneumoniae, were subsequently fixed. this seeded plate lacked sources of carbon and energy. ethanol formed in the agar blocks by the k. pneumoniae colonies diffused in ... | 1992 | 1418977 |
is small bowel bacterial overgrowth of pathogenic significance in persistent diarrhea? | bacterial overgrowth in the upper small intestine is postulated to cause persistent diarrhea. we compared the fecal and upper intestinal flora in 82 patients with persistent diarrhea aged < or = 36 months and weight-for-length < or = 90% of national center for health statistics standards (nchs) and 39 non-diarrheal children with age < or = 36 months, nutritionally matched with the patients and residing in the same environment. in the age groups < or = 12 months and > 12 months the duodenal fluid ... | 1992 | 1421924 |
proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins. | bac5 and bac7, antibiotics of the bactenecin (proline/arginine-rich peptide) family, are stored as proforms in the large granules of bovine neutrophils [zanetti, m., litteri, l., gennaro, r., horstmann, h. and romeo, d. (1990) j. cell biol. 111, 1363-1371]. these proforms have been purified to homogeneity from granule extracts by immunoaffinity and reverse-phase chromatography. while mature bactenecins efficiently kill escherichia coli, klebsiella pneumoniae and salmonella typhimurium with minim ... | 1992 | 1425666 |
importance of the environment and the faecal flora of infants, nursing staff and parents as sources of gram-negative bacteria colonizing newborns in three neonatal wards. | gram-negative bacteria are an important cause of invasive infection among neonates. in this study a novel fingerprinting method was used for the first time to assess the importance of various potential reservoirs of the major gram-negative enterobacteria that colonized 46 consecutive infants in three neonatal special care units during a three to four week period. such bacteria were isolated from the oropharynx, umbilical cord and faeces in 24%, 33% and 100% of the infants, respectively. klebsiel ... | 1992 | 1428181 |
gram-negative bacterial infection in neonatal new world camelids: six cases (1985-1991). | gram-negative bacterial infections were documented in 6 neonatal new world camelids (5 ilamas and 1 alpaca). the organisms isolated from blood before death or from multiple organs after death were escherichia coli (n = 3), actinobacillus sp (n = 1), and klebsiella pneumoniae (n = 1). only 2 crias survived, and 1 became blind secondary to retinal detachment and ocular inflammation, which developed after treatment for bacterial infection. abnormal events during the perinatal period (prematurity, d ... | 1992 | 1429194 |
extended spectrum beta-lactamase from klebsiella oxytoca, not belonging to the tem or shv family. | in clinical isolates of klebsiella oxytoca resistance to cefuroxime and aztreonam was mediated by a beta-lactamase, designated kh, (pi 5.25) which could be transferred into escherichia coli by electroporation, but not by conjugation. the transformants produced two enzymes with pis 5.25 and 8.4 respectively, and showed resistance to cefuroxime, aztreonam, cefotaxime and ceftazidime. substrate and inhibition profiles indicated that kh beta-lactamase was different from tem- or shv-like enzymes, but ... | 1992 | 1429334 |
a locus that contributes to colonization of the intestinal tract by bacteroides thetaiotaomicron contains a single regulatory gene (chur) that links two polysaccharide utilization pathways. | previously, we isolated two tn4351-generated mutants of bacteroides thetaiotaomicron (46-1 and cs3) that were unable to grow either on heparin or on chondroitin sulfate. this phenotype was unexpected, since the heparin and chondroitin sulfate utilization pathways had appeared from earlier studies to be independent of each other. mutants 46-1 and cs3 were also of interest because both were unable to compete successfully with wild-type b. thetaiotaomicron in the intestinal tracts of germfree mice. ... | 1992 | 1429442 |
the helix-turn-helix motif of sigma 54 is involved in recognition of the -13 promoter region. | residue arg-383 in the proposed helix-turn-helix motif of the novel rna polymerase sigma factor sigma 54 has been changed by site-directed mutagenesis to all possible alternative amino acids. only two mutants, rk383 and rh383, are active in promoting transcription from either the glnap2 promoter or the nifl promoter. we constructed a set of mutant derivatives of glnap2 such that each base in the conserved gg and gc doublets at -24 and -12 was changed to all possible alternatives. all 12 mutant g ... | 1992 | 1429447 |
analysis of eight out genes in a cluster required for pectic enzyme secretion by erwinia chrysanthemi: sequence comparison with secretion genes from other gram-negative bacteria. | many extracellular proteins produced by erwinia chrysanthemi require the out gene products for transport across the outer membrane. in a previous report (s. y. he, m. lindeberg, a. k. chatterjee, and a. collmer, proc. natl. acad. sci. usa 88:1079-1083, 1991) cosmid pcpp2006, sufficient for secretion of erwinia chrysanthemi extracellular proteins by escherichia coli, was partially sequenced, revealing four out genes sharing high homology with pulh through pulk from klebsiella oxytoca. the nucleot ... | 1992 | 1429461 |
appendix. sequence of the beta-subunit of oxaloacetate decarboxylase from klebsiella pneumoniae: a correction of the c-terminal part. | | 1992 | 1429628 |
electrophoretic studies on the assembly of the nitrogenase molybdenum-iron protein from the klebsiella pneumoniae nifd and nifk gene products. | the electrophoretic properties of the molybdenum-iron (mofe) protein component of nitrogenase and an iron-molybdenum cofactor (femoco)-reactivatable apomofe protein from klebsiella pneumoniae were examined under anaerobic ([o2] < 5 ppm), nondenaturing conditions. in wild type k. pneumoniae extracts, two immunoreactive species migrating more slowly than purified mofe protein were detected using anti-mofe protein antibodies. the uppermost species comigrates with the apomofe protein produced by a k ... | 1992 | 1429737 |
umbilical catheter-related resistant klebsiella septicaemia in a pre-term infant successfully treated with imipenem via the catheter. | | 1992 | 1431180 |
[study on lymphocyte-response in early stage of respiratory infection--a view point from experimental klebsiella pneumoniae pneumonia]. | this study was performed to demonstrate the early immuno-responses of lymphocytes in an experimental pneumonia with k. pneumoniae in mature mice (45 week-old) comparing with it in juvenile ones (4 week-old). acute mice pneumonia was made by inhalation with k. pneumoniae dt-s strains into lung. changes in lymphocytes including their subpopulation in bronchoalveolar lavage fluid (balf), peripheral blood, hilar lymphnodes and lung tissue were observed after the inhalation. in addition, lung tissue ... | 1992 | 1431351 |
activation of human monocyte chemiluminescence response by acylpoly(1,3)galactosides derived from klebsiella pneumoniae. | the stimulating activity of several preparations isolated from a membrane proteoglycan of a nonencapsulated smooth strain of klebsiella pneumoniae (kp-mpg) on the oxidative burst of human blood monocytes was assessed by luminol-enhanced chemiluminescence (cl). five kp derivatives were studied: a 34-kd acylpoly(1,3)galactoside (apg), obtained by drastic alkaline hydrolysis and purified by chromatography; an apg preparation subjected to acid hydrolysis that removed the core part and all fatty acid ... | 1992 | 1431564 |
lienocolonic fistula following splenic abscess. | | 1992 | 1433047 |
[antimicrobial activities of major oral antibacterial agents against clinically isolated microbial strains from outpatients with respiratory tract infection]. | minimum inhibitory concentrations (mics) were determined for major oral antibacterial agents for clinically isolated microbial strains from materials collected from outpatients with respiratory tract infections in 1988, 1989 and 1990, and the following conclusions were obtained. 1. methicillin-resistant staphylococcus aureus (mrsa) appeared to be responsible for community-acquired respiratory tract infections, but there also was a tendency showing that mrsa increased year by year. 2. a tendency ... | 1992 | 1433904 |
[antibacterial activities of sisomicin against fresh clinical isolates]. | to investigate antibacterial activities of sisomicin (siso), mics of siso as well as other aminoglycosides (ags) were determined against many clinical isolates which were obtained in 1991. results are summarized below: 1. no siso-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, proteus mirabilis and morganella morganii. 2. in comparison with the results of our previous study against isolat ... | 1992 | 1433905 |
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1988). i. susceptibility distribution]. | isolation frequencies and sensitivities to antibacterial and antibiotic agents were investigated on 801 bacterial strains isolated from patients with urinary tract infections in 9 hospitals during the period of june to november 1988. of the above total bacterial population, gram-positive bacteria accounted for 29.3% and a majority of them were enterococcus spp. gram-negative bacteria accounted for 70.7% and most of them were escherichia coli. 1. enterococcus faecalis: vancomycin was most active ... | 1992 | 1433906 |
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1988). iii. secular changes in susceptibility]. | sensitivities to various antibacterial and antibiotic agents of strains of escherichia coli, klebsiella spp., proteus spp., citrobacter spp., enterobacter spp., serratia marcescens and pseudomonas aeruginosa isolated from patients with urinary tract infections (utis) in 9 hospitals during june to november 1988 were compared with those in the same period of previous year according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and complicated utis with indw ... | 1992 | 1433908 |
[scleroma and rhinoscleroma]. | scleroma is a specific granulomatous disease of bacterial origin, chronic evolution, with election in respiratory tracts; nose lesion is practically constant and so justifies the term rhinoscleroma. although they are many endemic foci throughout the world and in particular in africa, it is an uncommon disease, often not recognized for polymorphic. the cases recorded out of already known foci concerned generally migrants; autochtonous cases in france are really infrequent. within the evolutive le ... | 1992 | 1435190 |
[bacteriological examination of paper money]. | bacteriological survey of one hundred twenty currency notes was done. aerobic spore-forming bacilli (91%), staphylococcus epidermidis (63.3%), staphylococcus aureus (4.2%), enterococcus (24.1%), alpha-hem. streptococcus (4.1%), streptococcus pneumoniae (1.7%), corynebacterium (7.5%), lactobacilli (10.8%), klebsiella pneumoniae (31.7%), enterobacter (19.2%), e. coli (17.5%), proteus (1.7%), pseudomonas aeruginosa (0.8%), shigella flexneri (0.8%) were isolated from paper money samples. currency no ... | 1992 | 1435365 |
acute renal failure secondary to acute bacterial pyelonephritis. | | 1992 | 1436327 |
urinary tract infection in infants in spite of prenatal diagnosis of hydronephrosis. | the efficacy of preventing neonatal urinary infection in infants by diagnosing hydronephrosis in the fetus on obstetrical ultrasonography was studied. 426 infants had uroradiologic evaluation between 1984 and june 1991 because they had hydronephrosis detected in utero. thirteen with posterior urethral valves were excluded. of the remaining 413, 13 (3.1%) presented with urinary infection in the first 6 months of life. ten of the 13 were boys and 7 were not circumcised. eleven of the 13 infants le ... | 1992 | 1437359 |
microorganisms associated with natural fermentation of prosopis africana seeds for the production of okpiye. | okpiye is a food condiment prepared by the fermentation of prosopis africana seeds. the traditional process for the production and microbiological characteristics of the condiment were investigated. during laboratory fermentation that lasted 96 h, the mesquite seeds underwent a natural fermentation that was characterised by the growth of microorganisms to 10(6)-10(8) cfu/g. several species of bacteria especially b. subtilis, b. licheniformis, b. megaterium, staphylococcus epidermidis and microco ... | 1992 | 1438073 |
[the diagnosis of acute pneumonia in respiratory viral infections]. | data are reported of 582 case records of patients with acute pneumonia of different influenza epidemic periods, results of a study of 175 lethal cases due to acute pneumonia, that complicated influenza in adults as well as experimental studies on reproduction of para-influenzal-staphylococcal, influenzal-klebsiella and proteus-influenzal infections. the study allowed to find out the causes of diagnostic difficulties, to establish the features of the course of acute pneumonia in patients with res ... | 1992 | 1441412 |
[the resistance plasmid of klebsiella pneumoniae that controls its cytotoxic activity]. | r-plasmid (40 md) isolated from k. pneumoniae hospital strain makes escherichia coli strain j62 capable of inducing a cytotoxic effect which can be detected in hep-2 cell culture. in contrast to the initial e. coli strain j62 producing no changes in the monolayer, e. coli j62 cells containing p-plasmid induced pronounced cytotoxic changes and a sharp increase in the number of nonviable hep-2 cells by hour 24 of interaction. | 1992 | 1441804 |
[the antigenic activity of vaccines made from opportunistic microorganisms in an experiment to immunize animals by oral and combined methods]. | the results of the study of the antigenic activity of multicomponent vaccine consisting of staphylococcal, klebsiella, proteus, escherichia coli antigens and staphylococcal monovaccine, introduced into rabbits and guinea pigs by different routes, are presented. as shown in this study, the multicomponent vaccine introduced orally in 5 administrations stimulated the production of antibodies to all components, but the intensity of antibody formation to each of them was different. antibodies to e. c ... | 1992 | 1441812 |
[interferon type i in protective body reactions in an experimental klebsiella infection]. | the study on mice with experimental generalized klebsiella infection, carried out with the use of microbiologic, immunologic and pathomorphologic methods, revealed that the intraperitoneal injection of type i interferon into the animals prevented their death and led to the rapid elimination of the infective agent from their body, enhanced the phagocytic and metabolic activity of polymorphonuclear lymphocytes of their peritoneal exudate, decreased the manifestation of microcirculatory and dystrop ... | 1992 | 1441818 |
[emphysematous cystitis caused by klebsiella pneumoniae]. | emphysematous cystitis is a very uncommon clinical activity as compared to the high incidence of urinary infections in diabetic patients. the paper explains the pathophysiological mechanisms and updates its clinical and therapeutic diagnostic choices regarding one case of favourable evolution following medical treatment. | 1992 | 1442233 |
which prophylactic regimen for which surgical procedure? | for optimal prevention of infection subsequent to a surgical intervention, it is necessary to follow a series of general principles, including the classification of the type of surgical intervention, the characteristics of the antibiotic used, and the route and the time of its administration. moreover, with reference to the different types of surgery, other factors assume importance: the etiology of the infection and the ability of the antibiotic to achieve adequate levels in the tissues at the ... | 1992 | 1443355 |
serum and blister fluid pharmacokinetics and bactericidal activities of ampicillin-sulbactam, cefotetan, cefoxitin, ceftizoxime, and ticarcillin-clavulanate. | ampicillin-sulbactam, ticarcillin-clavulanate, cefoxitin, cefotetan, and ceftizoxime are promoted for the treatment of mixed aerobic-anaerobic bacterial infections. their activities have been compared in vitro but not in vivo. in order to assess the in vivo activities of these agents in serum and interstitial fluid, we administered single, intravenous doses of these antimicrobial agents to healthy subjects. concentrations of the antimicrobial agents in serum and suction-induced blister fluid and ... | 1992 | 1444304 |
physiological studies of chloramine resistance developed by klebsiella pneumoniae under low-nutrient growth conditions. | this study investigated the physiological mechanisms of resistance to chloramines developed by klebsiella pneumoniae grown in a nutrient-limited environment. growth under these conditions resulted in cells that were smaller than cells grown under high-nutrient conditions and extensively aggregated. cellular aggregates ranged from 10 to more than 10,000 cells per aggregate, with a mean population aggregate size of 90 cells. this aggregation may have been facilitated by the presence of extracellul ... | 1992 | 1444406 |
biologically active complexes of nickel(ii), copper(ii) and zinc(ii) with schiff-base ligand derived from the reaction of 2-aminopyridine and pyrrol-2-carboxaldehyde--their synthesis and characterisation. | a new schiff-base ligand n-(2'-pyrrylmethylidene)2-aminopyrimidine derived from the reaction of 2-amino pyrimidine and pyrrol-2-carboxaldehyde and its nickel(ii), copper(ii) and zinc(ii) complexes have been synthesised and characterised on the basis of elemental analysis, molar conductance, infrared, electronic and proton nuclear magnetic resonance (1h-nmr) and magnetic susceptibility data. the ligand and its complexes when screened for antibacterial activity against bacterial species such as, e ... | 1992 | 1446377 |
fasting hypochlorhydria with gram positive gastric flora is highly prevalent in healthy old people. | fifteen healthy old people mean age 84 years (range 80-91 years), were examined to assess the effect of advanced age on the microecology of the upper gastrointestinal tract. twelve of 15 (80%) were hypochlorhydric with ph 6.6 (0.3) (mean (sem) and a mean bacterial count of 10(8) colony forming units (cfu) per ml (range 10(5)-10(10)) in fasting gastric aspirate. normochlorhydric subjects had low counts (< or = 10(1) cfu/ml). the microbial flora was dominated by viridans streptococci, coagulase ne ... | 1992 | 1446855 |
pefloxacin and immunity: cellular uptake, potentiation of macrophage phagocytosis and intracellular bioactivity for klebsiella pneumoniae. | antibiotic potentiation of host defence mechanisms may be of potential clinical importance in the outcome of infections. therefore the effect of pefloxacin upon the interaction of in vitro of human macrophages with klebsiella pneumoniae, by assays of antibiotic cellular uptake, bacterial phagocytosis and intracellular killing, was examined. the results indicated that pefloxacin was well concentrated by phagocytes at all the concentrations tested. the uptake proceeded rapidly and was not affected ... | 1992 | 1446977 |
analysis of polar lipids from some representative enterobacteria, plesiomonas and acinetobacter by fast atom bombardment-mass spectrometry. | fast atom bombardment-mass spectrometry (fab-ms) was used to analyse lipid extracts of bacteria to assess its usefulness for analysing anionic phospholipids of potential chemotaxonomic value. the following micro-organisms were tested: acinetobacter calcoaceticus, acinetobacter sp., citrobacter freundii, enterobacter cloacae (2 strains), escherichia coli (3 strains), hafnia alvei, klebsiella oxytoca, klebsiella pneumoniae, morganella morganii, plesiomonas shigelloides, proteus mirabilis (3 strain ... | 1992 | 1447059 |
cloning of the escherichia coli sor genes for l-sorbose transport and metabolism and physical mapping of the genes near meth and iclr. | the sor genes for l-sorbose (sor) degradation of escherichia coli ec3132, a wild-type strain, have been cloned on a 10.8-kbp fragment together with parts of the meth gene. the genes were mapped by restriction analysis, by deletion mapping, and by insertion mutagenesis with tn1725. seven sor genes with their corresponding gene products have been identified. they form an operon (gene order sorcpcdfbame) inducible by l-sorbose, and their products have the following functions: sorc (36 kda), regulat ... | 1992 | 1447144 |
bacterial biofilm formation in the urinary bladder of spinal cord injured patients. | ten spinal cord injured patients aged 8 to 55 years (mean 32) were followed for up to 2 months after admission to a rehabilitation setting from an acute care hospital. urinary fluid and bladder epithelial cells were collected weekly by intermittent catheterization and examined for bacterial colonization. six patients had no history of urinary tract infection upon admission, likely due to the antimicrobial coverage given during acute care. all the patients subsequently became colonized with uropa ... | 1992 | 1448299 |
putative nickel-binding sites of microbial proteins. | nickel is biologically important because of its catalytic role in the mechanisms of action of metalloenzymes, and also because of its toxic cellular effects. there exist at least 3 groups of nickel-binding proteins in microorganisms: nickel-specific transporters, accessory proteins involved in nickel incorporation and nickel-containing enzymes. the differences in their physiological functions determine the nature of the ligands and the structures of the nickel-binding sites. the homology among t ... | 1992 | 1448619 |
virulence of silver-resistant mutant of klebsiella pneumoniae in burn wound model. | a silver-resistant mutant of klebsiella pneumoniae b-5 was produced by passaging in nutrient broth containing graded concentrations of silver nitrate up to 150 ppm. the development of silver resistance in the strain resulted in rough colonies, decrease in cell size, carbohydrate content and change in klebocin pattern. the virulence of the agr strain as checked by the burn wound model decreased as the mutant could not establish itself in the skin and spleen of the animals and the organism was cle ... | 1992 | 1452094 |
enap-2, a novel cysteine-rich bactericidal peptide from equine leukocytes. | we purified a novel cysteine-rich antibiotic peptide, enap-2 (m(r), approximately 6,500), from acid extracts of equine neutrophils by sequential gel filtration and reversed-phase high-performance liquid chromatography and determined its partial n-terminal amino acid sequence. although its cysteine motif distinguished enap-2 from all other currently known endogenous antibiotic peptides, including defensins and granulins, it showed substantial sequence similarity to wdnm1, a putative member of the ... | 1992 | 1452336 |
ovine pulmonary surfactant induces killing of pasteurella haemolytica, escherichia coli, and klebsiella pneumoniae by normal serum. | pulmonary surfactant has been shown to play an increasingly important role in bacterial clearance at the alveolar surface in the lung. this study describes a bactericidal mechanism in which ovine pulmonary surfactant induces killing of pasteurella haemolytica by normal serum. to demonstrate killing, six bacterial species were incubated first with pulmonary surfactant for 60 min at 37 degrees c and then with serum for an additional 60 min at 37 degrees c. p. haemolytica type a1 strains 82-25 and ... | 1992 | 1452351 |
effects of sodium valproate on the immune response. | the effects of long-term treatment with sodium valproate (val) on humoral immunity (jerne plaque assay) and the delayed-type hypersensitivity (dth) response of mice were studied. the resistance of treated animals to bacterial infection was also investigated. various doses of sodium valproate were administered intraperitoneally (on alternate days) for periods of 1, 3 and 7 weeks. although treatment for 1 week produced no significant effect, val treatment (50 and 150 mg/kg/48 h) for periods of 3 a ... | 1992 | 1452398 |
modulation of surface antigen expression by klebsiella pneumoniae in response to growth environment. | growth in pooled human body fluids [urine, serum and peritoneal dialysate (hpd)] modulated the expression of cell envelope antigens in virulent (serotype o1:k1) and avirulent (serotype o1:k66) klebsiella pneumoniae strains. marked variations in the outer membrane protein (omp) and lipopolysaccharide (lps) profiles were noted when broth-grown cells were compared with those of bacteria cultured in body fluids. in particular, for the o1:k1 serotype strain, growth in the latter resulted in: (a) the ... | 1992 | 1453927 |
some of the out genes involved in the secretion of pectate lyases in erwinia chrysanthemi are regulated by kdgr. | the out genes of erwinia chrysanthemi are required for the translocation across the outer membrane of pectate lyases and cellulases. we present the characterization and the nucleotide sequence of five genes of the out cluster. the products of outs, b, c, d and e have significant homology with the puls, b, c, d and e proteins necessary to the secretion of pullulanase in klebsiella pneumoniae. an open reading frame, outt, located between outb and outc has no homology with the pul cluster but is in ... | 1992 | 1453958 |
a descriptive analysis of urine cultures: pure versus mixed isolates. | out of 5,670 urine cultures performed in 1989, 1,448 positive cultures with unique results were analyzed. of these 1,448, 67% were pure cultures, and 50% had at least one isolate with a colony count greater than 100,000 colony forming units/ml. pseudomonas aeruginosa, enterococcus faecalis, proteus mirabilis, klebsiella pneumoniae, staphylococcus aureus, and diphtheroids were more likely (p < 0.01) to occur in mixed than pure culture, while escherichia coli was more likely to occur in pure than ... | 1992 | 1454171 |
immunomodulatory action of propolis: iv. prophylactic activity against gram-negative infections and adjuvant effect of the water-soluble derivative. | the efficacy of the water-soluble derivative (wsd) of natural propolis (bee glue) was examined for augmentation of host resistance against experimental infections caused by gram-negative pathogens (klebsiella pneumoniae, proteus vulgaris, escherichia coli, pseudomonas aeruginosa). the substance was found to induce significant non-specific protection, but did not inhibit the in vitro growth of the same strains. pretreatment with wsd prior to the standard scheme for tumour necrosis factor (tnf) in ... | 1992 | 1455907 |
[the effect of phospholipids on the adhesive properties of bacteria]. | the present work shows that choline-containing phospholipids (lysophosphatidylcholine and lyso-1-alkyl-sn-glycerophosphocholine) inhibit the adhesion of some strains: bacterium bifidum 1, b. adolescentis mc-42, b. longum b. 379m, staphylococcus aureus p 209 and klebsiella pneumoniae 52. phosphatidylcholine produces no effect on the adhesiveness of these strains, while platelet activation factor stimulates adhesiveness only in strain s. aureus 209. the stimulating or inhibiting action of phosphol ... | 1992 | 1455967 |
[antibacterial effects of gamma-interferon in experimental klebsiella infection]. | the results of the experimental study on the effect of the natural and recombinant gamma-interferons (gamma-ifs) of mice on the process of the infection caused by klebsiella sp. are presented. the infection was reproduced by intraperitoneal contamination of mice with a virulent culture of klebsiella pneumoniae 5055, line shk. the gamma-ifs were administered to the animals in a dose of 250 units per mouse on days 1 and 3 after the contamination. survival of the animals, clearance of the pathogen ... | 1992 | 1456806 |