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prescription and misuse of benzodiazepines in the federal republic of germany.reliable benzodiazepine prescription data are now available for the federal republic of germany by the establishment of gkv-index. in 1981, 4 benzodiazepines were among the 25 highest ranking drugs in the frg according to total number of prescriptions. a decline of benzodiazepine prescriptions was observed in 1983 and 1984; two short-acting compounds achieved a higher ranking position. benzodiazepines make up to about two thirds of all psychotropic drugs prescribed. these data are compared to so ...20062870514
the connecticut state medical society: its antecedents and early history. 20061458881
the pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis.twenty-six patients with unilateral and bilateral hydronephrosis were subjected to investigation to identify the patterns of pra-aldosterone system. the incidence of hypertension in the unilateral group was 28.5%, while in the bilateral group it was 50%; the overall incidence was 34.6%. in the hypertensive patients (9 cases), plasma renin activity and aldosterone were normal in one, and elevated in three. aldosterone only was elevated in 3 cases, while pra was elevated in 2. in the normotensive ...20063294713
prognostic indicators in fulminant hepatic failure.because of the inhomogeneous prognosis in fulminant hepatic failure, prognostic criteria are required which help to establish the indication for liver transplantation as a successful therapeutic procedure. in our study of 33 patients with fulminant hepatic failure (94% viral hepatitis, 67% hepatitis b), serum bilirubin > 320 or < 160 mumol/l, serum creatinine > 110 mumol/l, prothrombin time < 15% of the normal value and duration of jaundice until onset of encephalopathy > 7 days indicated a fata ...20061449004
ergotamine-metoclopramide for migraine: is it enough? 20061446995
laparoscopic vagotomy: a new tool in the management of duodenal ulcer disease. 20061422777
[pulmonary carcinomatous lymphangitis and renal adenocarcinoma].the case of a 7 year-old who presented with lymphangitic carcinomatosis revealed by lung biopsy and secondary to renal adenocarcinoma is described. this biopsy was performed because of radiologic and clinical signs associating bilateral interstitial infiltrates, mediastinal adenopathy and gradually increasing respiratory distress. despite treatment, the child died two weeks later.20062082848
single determination of ca 15.3 and bone scintigraphy in the diagnosis of skeletal metastases of breast cancer.single determination of ca 15.3 and bone scintigraphy were performed on the same day as follow-up procedures in 864 patients with breast cancer. the sensitivity and specificity of bone scintigraphy for skeletal metastases were 99% and 88.8%, respectively. the overall sensitivity and specificity of ca 15.3 (cut-off for pathological values greater than 30 u/ml) for cancer recurrence or distant metastases were 69.2% and 92.1%, respectively. the sensitivity of ca 15.3 for bone metastases was lower ( ...20061450226
vasomotion in venous disease.abnormalities of the capillary microcirculation may be important in the pathogenesis of venous ulceration. in this study the characteristics of capillary vasomotion in venous disease have been studied using laser doppler flowmetry. the amplitude and frequency of vasomotion in the skin microcirculation as measured by laser doppler flowmetry was determined in 101 subjects. these comprised 43 subjects with venous disease and lipodermatosclerosis (lds), 14 subjects with uncomplicated varicose veins ...20061828270
parity, ethnic group and the prevalence of type 2 diabetes: the coventry diabetes study.the prevalence of type 2 (non-insulin-dependent diabetes) in relation to parity was compared among south asian (asian) and european women during a cross-sectional house-to-house screening programme for diabetes in foleshill, coventry, uk. the parity of female residents was ascertained in 8 of the 12 areas visited. these areas contained 2096 european (68 with diabetes diagnosed) and 1148 asian women (95 with diabetes diagnosed). crude prevalence of type 2 diabetes was 3.2% and 14.7% in europeans ...20061395461
the prognostic value of fetal ultrasonography before induction of labour.to investigate whether ultrasound examination of the fetus and amniotic fluid before induction of labour can provide useful prognostic information about the course of labour and mode of delivery.20061450140
single and multigland disease in primary hyperparathyroidism: clinical follow-up, histopathology, and flow cytometric dna analysis.two-hundred seventy-four patients with primary hyperparathyroidism had selective removal of enlarged parathyroid glands. biopsies were taken from all parathyroid glands. normal-size glands were not resected irrespective of their histological appearance. after a mean follow-up of 13.5 years the rates of persistent and recurrent hyperparathyroidism were, respectively, 3.6% and 0.7%. transient and permanent hypoparathyroidism occurred in 24% and 2.5% of the patients. the microscopic appearance of e ...20061413843
pseudo-chediak-higashi anomaly in acute myeloid leukemia (m2) of childhood.the frequency and clinical significance of the pseudo-chediak-higashi (pch) anomaly were studied in 20 children with acute myeloid leukemia (aml) m2 in the fab nomenclature. pch granules were recognized as giant eosinophilic granules, measuring up to 5 microns, in the cytoplasm of leukemic cells on smears. at the electron microscope level, most pch granules were round to oval and outlined by a limiting membrane, and contained homogeneous, granular, crystalloid, rod-like or myelin-like materials. ...20062082666
proposal of a computerized algorithm for continuous wave co2 laser on-line control during orthopaedic surgery. phase i: theoretical introduction and first in vitro trials.new data obtained from treating polymethylmethacrylate (pmma) with a non-moving cw- 10 watt-co2 laser-beam focused at 2.5'', 5'', 7.5'' and 15.75'' are presented. . the final equations r(tc) and z(tc) for each focal length are proposed. a very interesting correlation between the focal lengths in use and the integrated values of r and z between 0 and 2 sec has been identified and discussed. this result has been used as basis to define a convenient operative protocol to follow during the planning ...20061402302
production-scale purification processes. 20061367135
cranio-nasal median splitting for radical resection of craniopharyngioma.a new surgical approach for radical resection of craniopharyngioma is presented. this approach (cranio-nasal median splitting) involves craniotomy in the centre of the frontal bone, removal of the median portion of the supraorbital bar that incorporates the nasal bone, and detachment of the medial canthal ligaments. the frontal lobes, the cribriform plates, the planum sphenoidale, and the upper nasal cavities are split in the midline. the extraventricular surface of the hypothalamus, the pituita ...20061360632
[indications and role of surgery in painful dysfunction syndromes of the masticatory apparatus].among the numerous causes of facial neuralgias, the painful dysfunction syndrome of the manducatory apparatus corresponds to a frequent etiology whose thorough study carried out by a multidisciplinary team over about 500 cases allowed their splitting into several evolutive clinical forms. at present, a number of these forms which are particularly painful, require a disk surgery (dislocation reduction, perforation suture, etc.) and if necessary an articular facet surgery (modelling condylectomy, ...20061345711
atomic absorption determination of mercury in fish using the coleman mas-50 mercury analyzer. 20064472005
synthesis and cytotoxicity studies of 8-amino-6-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthyle ne (7-aza-tcn) and the corresponding 2'-deoxy- and arabinonucleoside analogues.the tricyclic nucleoside 8-amino-6-n-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene was synthesized from 8-amino-6-n-methyl-4-(methylthio)-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene. the 2'-deoxy analogue of 5, 8-amino-6-n-methyl-2-(2-deoxy-beta-d-ribofuranosyl)-1,2,3,5,6, 7-hexaazaacenaphthylene (11), and the arabino analogue of (5), 8-amino-6-n-methyl-2-beta-d-arabinofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene (14) were synthesized from 5. nucleosides 2,3,4,5, ...20072258902
synthesis and cytotoxicity studies of 8-amino-6-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthyle ne (7-aza-tcn) and the corresponding 2'-deoxy- and arabinonucleoside analogues.the tricyclic nucleoside 8-amino-6-n-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene was synthesized from 8-amino-6-n-methyl-4-(methylthio)-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene. the 2'-deoxy analogue of 5, 8-amino-6-n-methyl-2-(2-deoxy-beta-d-ribofuranosyl)-1,2,3,5,6, 7-hexaazaacenaphthylene (11), and the arabino analogue of (5), 8-amino-6-n-methyl-2-beta-d-arabinofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene (14) were synthesized from 5. nucleosides 2,3,4,5, ...20072258902
a giant renal stone. 20072224443
a giant renal stone. 20072224443
arytenoidectomy and posterior cordectomy for bilateral abductor paralysis.twelve patients with bilateral fixed vocal cords seeking decannulation of their tracheostomies were subjected to endoscopic correction of the compromised airway. they all had arytenoidectomy associated with posterior cordectomy whether as a primary or secondary stage procedure. decannulation was achieved in all patients using the technique described.20072072014
[the auscultation method of measuring arterial blood pressure (history of its invention and the current aspects of its use]. 20072084325
the use of adrenal substance in the treatment of asthma. 1900. 20072266071
the use of adrenal substance in the treatment of asthma. 1900. 20072266071
[the genetic and pathogenetic mechanisms of atherosclerosis]. 20072077272
vocational integration for the psychiatrically disabled. 20072793094
postoperative recurrence of splenic epithelial cyst; treatment with subtotal splenectomy.three children were operated upon for congenital epithelial cysts of the spleen in the five-year period 1983-1987. their mean age was 9.8 +/- 2.3 years. two of them were boys. they comprise 1.6% of the surgical pathology of the spleen in our hospital, which is a reference centre for congenital haemolytic diseases. two of the children had been suffering from intermittent colic pain in the left hypochondrium with a tender palpable mass for a short while to the present day. the third patient was as ...20072238852
postoperative recurrence of splenic epithelial cyst; treatment with subtotal splenectomy.three children were operated upon for congenital epithelial cysts of the spleen in the five-year period 1983-1987. their mean age was 9.8 +/- 2.3 years. two of them were boys. they comprise 1.6% of the surgical pathology of the spleen in our hospital, which is a reference centre for congenital haemolytic diseases. two of the children had been suffering from intermittent colic pain in the left hypochondrium with a tender palpable mass for a short while to the present day. the third patient was as ...20072238852
[the present share of health services financing provided by state enterprises].at the moment none of the managing departments is concerned with investigations of financing of factory health facilities by enterprises and organizations. a pilot study revealed that hitherto valid methods of investigation of these costs, as regards investments, were not very successful and thus it is very difficult to follow up these data. as regards operational costs, considerable differences were revealed between different departments in their contribution to the costs of factory health faci ...20072706696
four spreadsheet templates for the laboratory.four spreadsheet templates have been devised to ease certain laboratory operations, namely preparing buffers by mixing solutions, calculating required rotor speeds to achieve particular g-values, preparing and utilising isokinetic gradients to determine sedimentation coefficients, and calculating purification tables. their use in designing experiments is described briefly.20073450351
stabilization of glucose transporter mrna by insulin/igf-1 and glucose deprivation.chronic exposure of l6 myocytes to insulin/igf-1 or glucose deprivation results in an increase in the level of brain-type glucose transporter (glut1) mrna. we have investigated the effects of insulin and glucose deprivation on glut1 mrna stability. the half-life of glut1 mrna in control cells was 2-2.5 h. insulin increased glut1 mrna levels by 5- to 10-fold, and glut1 mrna half-life and transcription by 2-fold. glucose deprivation increased glut1 mrna level by 2- to 4-fold and half-life by 2-fol ...20072168170
industrial airborne irritant or allergic contact dermatitis.industrial airborne irritant or allergic contact dermatitis is commonly observed in many factories. examples of airborne irritants include fibres (such as fibreglass or rockwool), various kinds of dust particles (such as cement, slag, sludge, insulating foam, wood chips), acids and alkalis, gasses and vapours. airborne contact allergens are unequivocally numerous. the clinical symptoms of both irritant and allergic airborne contact dermatitis are reviewed.20072940059
[against the drainage of the abdominal cavity in diffuse purulent peritonitis]. 20075054109
[the effect of glycine and gamma-aminobutyric acid on the evoked activity of the spinal cord motor neurons in the lamprey].the influence of bath application of glycine (10(-5)-10(-3) mol/l) and gamma-aminobutyric acid (10(-5)-10(-2) mol/l) on the monosynaptic epsps evoked in motoneurons by stimulation of a descending tract and individual müller axons was studied in spinal cord-notochord preparation of lamprey (lampetra fluviatilis). both amino acids hyperpolarized the motoneuron membrane and depressed the evoked synaptic activity. but the inhibitory effect of glycine was stronger and it was revealed at lower concent ...20072169033
nonsurgical bypass of malignant duodenal and biliary obstruction. 20072121584
altitude diuresis: endocrine and renal responses to acute hypoxia of acclimatized and non-acclimatized subjects.as a result of our recently published studies we have thought that altitude diuresis resulting from hypoxic stimulation of the arterial chemoreceptors reduces the cardiac volume overload. to test this hypothesis, cardiovascular, endocrine and renal responses to stepwise acute exposure to simulated altitude (6,000 m) were compared in ten acclimatized recumbent mountaineers a mean of 24 days, sd 11, after descending from himalayan altitudes of at least 4,000 m, with those found in ten non-acclimat ...20072044531
biphasic changes in leukocytes induced by strenuous exercise.seven healthy male volunteers participated in short- (str, 1.7 km), middle- (mtr, 4.8 km) and long- (ltr, 10.5 km) term runs at a speed close to their maximum. a prompt mobilization of white cells, and lymphocytes in particular, appeared following the exercise. the initial increase in the number of lymphocytes was succeeded by a significant decrease [(p less than 0.03) lymphopenial], which on average was 32%-39% of the pre-exercise values in all groups. a close correlation was found between the ...20072044521
the valsalva manoeuvre. 20072391301
[primary projection of receptors of extrinsic ocular muscles: anatomical results].recently, several electrophysical studies have shown that extraocular sensory afferents projected onto subcortical nuclei and cortical area as well. in a recent study of the projection fields of the primary afferent fibers from extraocular muscles, it has been shown that the intermediate layers of the cervical dorsal horn of the spinal cord was one of the recipient zone.20071951928
[efficacy and tolerance to mebhydroline in comparison with dimetindene maleate]. 20072870838
[efficacy and tolerance to mebhydroline in comparison with dimetindene maleate]. 20072870838
objective verification of dietary intake by measurement of urine osmolality.a new method for assessing the accuracy of dietary nutrient intakes in metabolic studies is described. the theoretical basis of the method is the comparison of measurements of the urine osmole excretion rate (oer, the product of urine osmolality and urine weight) with values for oer predicted from dietary nitrogen, sodium, and potassium. the method was tested in 34 healthy male and female volunteers aged 18-78 y who made complete 24-h urine collections and consumed a diet over 6 d in metabolic-b ...20071951146
recognition of nonexplicitly presented odors.this research was designed to check to what extent naive subjects can recognize odors in a situation similar to those of daily life. the odors were presented nonexplicitly and without any warning to memorize them for a later recognition task. different intensities of noise were used to verify whether these affect the olfactory recognition task by modifying arousal and check whether a situation made more unpleasant by a louder noise produces changes in subjects' evaluations of the pleasantness of ...20071891326
hardware for in-flight fixation of plants in microgravity.nasa-approved hardware was designed for an experiment involving in-flight fixation of 4.8-day-old seedlings of brassica perviridis. the hardware is inexpensive, reliable, and simple to construct. this hardware aboard flight 61-c of space shuttle columbia functioned perfectly, and required less than 0.5 hr of crew time for training. analyses of cellular ultrastructure indicated excellent ultrastructural preservation.20071888797
[assessment of endoscopic embolization in the management of esophageal varices].between february 1984 and september 1987, endoscopic embolization (ee) was performed in 26 patients with esophageal varices. the effects of ee were evaluated with endoscopic findings according to the general rules for recording endoscopic findings on esophageal varices as specified by the japanese research society for portal hypertension. 1) when the result was regarded as effective if a patient had cw, f1, r-c sign (-), li and lm or disappearance of varices, the improvement was found in 66.7% f ...20072753992
adult wilms' tumor. role of combined modality treatment.adults wilms' tumor, unlike its pediatric counterpart, is extremely rare and highly lethal. less than 200 cases have been reported in the world literature and a large proportion of these may not have been true wilms' tumors. we report 3 cases seen at our institution who were treated with a multimodality approach, all three remaining alive without evidence of active disease at 6 years, 2.25 years and 8 months respectively from diagnosis. we also review results of multimodality management, emphasi ...20072556167
undescended testis and orchiopexy: recent observations. 20071973283
[small hospitals--future tasks and functions].we review the small municipal hospitals included in our study of hospitals serving less than 50,000 persons. we identified the following problems: these hospitals are resource-intensive to a greater degree than expected, measured in terms of beds, doctors, health services and per capita costs in the area served by the hospital. moreover, their quality is questionable, due to problems of recruitment and lack of continuity, a weak infrastructure, and insufficient patients to maintain a high level ...20071871753
the production of transgenic mice by embryo microinjection.the production of transgenic mice is a technology of great utility in the dissection of complex biological processes. this article is intended as a detailed primer for people interested in learning to produce transgenic mice, and discusses equipment, methods, and future directions for this technique.20072064823
a screening test for slow metabolisers of tolbutamide.1. six subjects participated in a detailed pharmacokinetic study of tolbutamide (pilot study). using parameters based on these data, sixty-three non-diabetic volunteers underwent a simple screening test designed to identify slow metabolisers of tolbutamide. 2. the screening test was an estimate of tolbutamide plasma elimination half-life from plasma concentrations at 8 and 24 h after 500 mg tolbutamide orally, and urinary recovery of the hydroxy- and carboxytolbutamide metabolites over the 4-8 h ...20071867959
scoliosis.four basic criteria are important when determining which diseases are amenable to detection and treatment by screening: 1) the diagnostic test used must be highly sensitive, 2) the disease should cause substantial morbidity or mortality, 3) early detection and treatment should eliminate the disease or prevent its progression, 4) the incidence of the disease should be high enough to warrant the utilization of time, resources, and money. a review of three large screening studies evaluating the det ...20072693581
remodeling the image of nursing: a powerful strategy for clinical nurse specialists. 20071913441
salivary ph and glucose after consuming various beverages, including sugar-containing drinks. 20073475181
the irrationality of the catharsis theory of aggression as justification for educators' support of interscholastic football.the notion that hostile feelings can be catharted from the psyche by playing football or other aggressive sports was virtually destroyed by behavioral scientists several decades ago. nonetheless educators continue to support interscholastic football as a means of venting the aggressive emotions that supposedly characterize adolescence. this work examines this phenomenon, concluding that educators realize the sport actually increases aggression but hide behind the outdated hypothesis about cathar ...20071852552
[x-ray diagnosis of peripheral chondromatous hamartomas of the lungs].a roentgenomorphographic picture was compared with gross specimens of the lungs in 104 operated on patients with peripheral harmatochondromas. eighty three patients were followed-up roentgenologically for 2-18 years. the resultant three variants of an x-ray picture of hamartochondromas were revealed. ct investigation showed a benign process in a majority of patients, hamartochondrosarcoma was diagnosed in 36.5 per cent. shadow size enlargement, calcifications and their increase are not signs of ...20071839095
reactions of dinitrogen pentoxide and nitrogen dioxide with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine.the reactions of gaseous dinitrogen pentoxide (n2o5) and nitrogen dioxide (no2) with 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (popc) coated on the inside surface of a glass reaction cell were studied at 298 k. unsaturated phosphatidylcholines are significant components of pulmonary surfactant in the alveolar region of the lung and hence serve as a simple model to examine reactions of pulmonary surfactant with these oxidant air pollutants. using high-performance liquid chromatography (hp ...20071865766
[a case of candidiasis in a patient with chronic fungal infection, secondary immunodeficiency and cushing's syndrome]. 20071865667
health care's future. 20071866119
[degenerative encephalopathy of probable viral etiology in the course of congenital agammaglobulinemia]. 20072096763
serum somatomedin activity following adult tibial shaft fractures.serum somatomedin (sm) activity was measured serially in 27 adults with closed tibial shaft fractures. sm activity was found to be normal in all but one specimen. the results indicate that sm activity does not reflect severity of trauma or the ability to heal on time in these fractures.20072613308
[magic and exorcism in paris (apropos of 3 cases)]. 20071952539
[epidemiology and heterogeny].the innovation of epidemiology plays a crucial role in the development of the health sciences. the authors emphasize the importance of epistemological analysis related to scientific and technical production. they focus on the theoretical and methodological contributions of the principal latin american groups in the field of epidemiology, stating their main accomplishments, issues and potentials. when reviewing those conceptual and practical innovations, the authors analyse the effects of broader ...20082660269
[epidemiology and heterogeny].the innovation of epidemiology plays a crucial role in the development of the health sciences. the authors emphasize the importance of epistemological analysis related to scientific and technical production. they focus on the theoretical and methodological contributions of the principal latin american groups in the field of epidemiology, stating their main accomplishments, issues and potentials. when reviewing those conceptual and practical innovations, the authors analyse the effects of broader ...20082660269
auditory physiology: present trends. 20082648981
cystadenoma and cystadenocarcinoma of the pancreas.during the period 1963 to 1988, we treated 45 patients with cystic neoplasms of the pancreas. the patients were divided into group 1, which included 26 patients treated between 1963 and 1983, and group 2, which included 19 patients treated between 1984 and 1988. the rate of resection for cystadenoma was 67% for group 1 (n = 15) and 100% for group 2 (n = 11). the operative mortality rate was 0% for both groups. pathologically, 17 patients (69%) had serous cystadenoma and nine (31%) mucinous adeno ...20082613166
cystadenoma and cystadenocarcinoma of the pancreas.during the period 1963 to 1988, we treated 45 patients with cystic neoplasms of the pancreas. the patients were divided into group 1, which included 26 patients treated between 1963 and 1983, and group 2, which included 19 patients treated between 1984 and 1988. the rate of resection for cystadenoma was 67% for group 1 (n = 15) and 100% for group 2 (n = 11). the operative mortality rate was 0% for both groups. pathologically, 17 patients (69%) had serous cystadenoma and nine (31%) mucinous adeno ...20082613166
[1 year's experience with the multifunctional lithotriptor dornier mpl 9000].from march 1988 until may 1989, 361 patients with 438 stones were treated with the dornier multipurpose lithotripter mpl 9000. 64.8% of the stones were situated in the calyx, 32.6% in the renal pelvis, 1.1% in the upper and 1.4% in the distal ureter. 19.6% of the stones were radiolucent. multiple mpl treatments were performed in 10.2%. in 4.3% fragments post-eswl treatment were larger than 5 mm. in 95.7% of the cases complete disintegration was achieved. 63.5% of the treatments were performed wi ...20082634942
[laser therapy in the combined treatment of the trophic disorders in the postthrombophlebitis syndrome]. 20082593785
five groups of antigenic determinants on dna identified by monoclonal antibodies from (nzb x nzw)f1 and mrl/mp-lpr/lpr mice.a library of monoclonal antibodies (mca) reactive with dna was derived from mice with lupus-like disease. the combining reactions of the antibodies was determined by elisa, precipitation assay and indirect immunofluorescence assay on cells. on the basis of their reactions in these assays, the mca have been classified into five taxonomic groups. mca in group i react with conformational determinants on double-stranded dna (dsdna); those in group ii with conformational backbone-dependent sugar-phos ...20082581889
national study on the utilization of prophylactic antibiotics in surgery, belgium, 1986.during the last week of may 1986, a 1-week prospective study on antibiotic utilization in surgical patients was held in 104 (42%) of the 247 belgian acute care hospitals. all surgical patients with a post-operative stay of at least 3 days were studied, involving 3112 patients. each patient was observed for 7 days, starting from the day before surgery. antibiotics were administered to 71.9% of all patients; 21.9% received therapeutic antibiotics and 52.9% prophylactic antibiotics; 2.9% received b ...20082680549
sartorius muscle coverage for the treatment of complicated vascular surgical wounds.sartorius muscle flaps were evaluated in 14 patients treated for complicated groin wounds related to vascular surgical procedures. particular risk factors for poor wound healing were present in 8 patients, including diabetes, obesity, or poor nutrition in 3 patients; prior radiotherapy to the groin in 2; reoperative groin exposure in 3. eleven of 14 patients had multiple indications for sartorius flap coverage, including hemorrhage in 5 patients, groin wound sepsis in 3, graft sepsis in 2, wound ...20082745536
concomitant chronic lymphocytic leukemia, acute myeloid leukemia, and thrombosis with protein c deficiency. case report and review of the literature.a patient is reported who presented simultaneously with two distinct forms of leukemia: chronic lymphocytic leukemia (cll) and acute myeloid leukemia (aml). the diagnosis of cll was supported by the presence of lymphocytosis, lymphadenopathy, and splenomegaly with mature b-cell markers on the population of lymphoid cells in the bone marrow. aml was documented by the presence of circulating blast cells and 50% blasts with myeloid markers and auer rods in the bone marrow. a complete remission from ...20082646007
[the concept of developmentally-induced structural ego disorders--a reference frame for working with extremely borderline patients?].the concept of developmental-structural ego defects provides a therapeutic framework for the treatment of patients who have, in the past, largely been classified as untreatable. with emphasis on individual therapeutic treatment, this paper provides a critical introduction to the concept and discusses the applicability of this therapeutic approach for extremely lower-lower class patients: patients doubly stigmatized by psychological illness and criminality who are treated in a forensic-psychiatri ...20082587689
[the nurse, the nurses' aide, the practical nurse and the home health aide]. 20082749325
collagen protein abnormalities produced by site-directed mutagenesis of the pro alpha 1(i) gene.site-directed mutagenesis of collagen genes offers a powerful new approach for studying structure-function relationships. the construction of engineered mutant collagen genes coding for glycine substitutions and their expression giving rise to the osteogenesis imperfecta type ii phenotype in cells and transgenic mice has recently been achieved. this paper further defines the molecular abnormalities of collagen and bone pathology resulting from the expression of the mutant genes.20082612152
collagen protein abnormalities produced by site-directed mutagenesis of the pro alpha 1(i) gene.site-directed mutagenesis of collagen genes offers a powerful new approach for studying structure-function relationships. the construction of engineered mutant collagen genes coding for glycine substitutions and their expression giving rise to the osteogenesis imperfecta type ii phenotype in cells and transgenic mice has recently been achieved. this paper further defines the molecular abnormalities of collagen and bone pathology resulting from the expression of the mutant genes.20082612152
doppler echocardiographic findings in healthy chinese adults.to establish a norm for cardiac velocities in healthy chinese adults, we examined 30 normal subjects (15 men and 15 women) with pulsed- and continuous-wave doppler, and color flow mapping. the subjects ranged in age from 18 to 60 years (mean 37 years). we found that the early (e) and late (a) diastolic peak velocities for the mitral valve were 87 +/- 16 cm/sec and 61 +/- 15 cm/sec, respectively. the e/a ratio was 1.5 +/- 0.4. the e and a peak velocities for the tricuspid valve were 57 +/- 10 cm/ ...20082592939
[bone imaging in the detection of skeletal metastasis].tc-99m-hmdp bone imaging was performed in 114 patients with various carcinomas. ninety-four patients gave positive results. in 65 patients, bone imaging was compared with radiograms. the two methods were both positive in 40 patients (62%). of these 65 patients, 17 (26.1%) had negative radiograph but positive bone imaging. bone metastases were mainly found in the axial skeleton. it is important to differentiate bone fracture from metastasis when only one single lesion is found. the best different ...20082612332
[bone imaging in the detection of skeletal metastasis].tc-99m-hmdp bone imaging was performed in 114 patients with various carcinomas. ninety-four patients gave positive results. in 65 patients, bone imaging was compared with radiograms. the two methods were both positive in 40 patients (62%). of these 65 patients, 17 (26.1%) had negative radiograph but positive bone imaging. bone metastases were mainly found in the axial skeleton. it is important to differentiate bone fracture from metastasis when only one single lesion is found. the best different ...20082612332
current trends in cancer incidence in greenland. 20083272704
from activated patient to pacified activist: a study of the self-care movement in the united states.self-care education programs in operation in the united states during the mid-1980s are surveyed by mailed questionnaire to determine the nature and content of the curricula of these programs, their organizational sponsorship, the level and types of staff working in them, and their principal prevention emphases. results indicate that over 75% of these programs offer instruction or sponsored activities intended to help individuals or their families to: (1) increase wellness or health status throu ...20082749301
asynchronous assembly of the acetylcholine receptor and of the 43-kd nu1 protein in the postsynaptic membrane of developing torpedo marmorata electrocyte.the assembly of the nicotinic acetylcholine receptor (achr) and the 43-kd protein (v1), the two major components of the post synaptic membrane of the electromotor synapse, was followed in torpedo marmorata electrocyte during embryonic development by immunocytochemical methods. at the first developmental stage investigated (45-mm embryos), accumulation of achr at the ventral pole of the newly formed electrocyte was observed within columns before innervation could be detected. no concomitant accum ...20082642909
ethanol increases agonist affinity for nicotinic receptors from torpedo.the presence of ethanol increases the apparent affinity with which acetylcholine and carbamylcholine elicit 86rb+ flux from torpedo nicotinic acetylcholine receptor-rich vesicles at 4 degrees c. affinity increased exponentially with ethanol concentration, reaching nearly 200-fold by 3.0 m ethanol without sign of saturation. at submaximal agonist concentrations 50-100 mm ethanol enhanced flux by 15-35%, but the maximum agonist-induced flux was unaffected in quenched-flow assays. the effect was in ...20082597688
[the dynamic characteristics of regional muscle blood flow and the activity of mineralization processes in the bony callus with various methods of treating mandibular fractures].rmbf was comparatively assessed in patients with lower jaw fractures under orthopedic therapy of the osteal suture. to this end, the 99m pertechnetate was injected bilaterally in masseter muscles. the data suggest that double jaw fixation had an adverse effect on rmbf, especially ipsilateral to the fracture. nevertheless, the mineral metabolism intensity in the callus is higher under fixation as related to the cases surgically sutured.20082555937
[persistent mullerian duct syndrome].we report on a 14-year-old boy who was admitted to the emergency department for acute retention of urine. at age 1 year, he had been submitted to surgery for left cryptorchidism and left-sided herniation, associated with hypospadias of the glans penis. radiologic and endoscopic work up revealed a large retrovesical cavity with septation in its upper portion communicating with the prostatic urethra. these structures were removed and pathologic examination disclosed remnants of müllerian ducts. th ...20082573317
the inferior gluteal free flap in breast reconstruction.the inferior gluteal musculocutaneous free flap usually provides a sufficient amount of autogenous tissue for breast reconstruction when adequate tissue is not present in the lower abdomen or back. its arteriovenous pedicle is longer than the superior gluteal musculocutaneous free-flap pedicle and permits microvascular anastomosis in the axilla, avoiding medial rib and cartilage resection. in the thin patient, there is more available donor tissue than with the superior gluteal musculocutaneous f ...20082587651
effect of cepharanthin on superoxide anion (o2-) production by macrophages. 20082848880
[the correct use of beta 2 stimulants]. 20082566197
modulation of a 190-kd microtubule-associated protein in pigment epithelium by vip.vasoactive intestinal peptide stimulates phosphorylation of six high molecular weight cytosolic proteins in the cultured retinal pigment epithelium (rpe). of these, the 190-kd phosphoprotein is associated with the microtubules assembled by taxol/gtp and is immunologically related to the brain microtubule-associated protein 2 (mol.wt. = 280 kd). vip is also shown here to stimulate secretion in the cultured rpe. vip-stimulated phosphorylation of a 190-kd microtubule-associated protein is also demo ...20082575248
interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.the expression of the xenopus homoeobox gene xhox3 is an early response to mesoderm induction by peptide growth factors and the level of xhox3 expression marks the antero-posterior character of the induced mesoderm. different peptide growth factors specify different antero-posterior mesodermal cell fates as seen by the level of xhox3 expression and the capacity to induce specific secondary neural/epidermal structures. these factors and homoeobox genes thus form part of the mechanism necessary fo ...20082570357
the effects of h1 antihistamines on the early allergic response.to increase understanding of the effect of h1 antihistamines on the immediate response to nasal challenge with antigen, we performed two double blind, placebo-controlled, crossover studies using cetirizine and terfenadine. the subjects underwent nasal challenge with antigen after premedication with either cetirizine (20 mg qd for two days, n = 10), terfenadine (60 mg bid for 1 week, n = 12), or placebo for equivalent periods of time. we monitored the response to challenge by counting the number ...20082574550
use-dependent block of sodium channels in frog myelinated nerve by tetrodotoxin and saxitoxin at negative holding potentials.na+ currents were measured in myelinated frog nerve fibres in the presence of nanomolar concentrations of tetrodotoxin (ttx) or saxitoxin (stx) in the extracellular solution. the na+ currents declined during a train of depolarizing pulses if the fibre was held at hyperpolarizing potentials between the pulses. at a pulse frequency of 0.8 hz, the peak na+ currents were reduced to 70 or 60% of the initial value in 9.3 nm ttx and 3.5 nm stx solutions, respectively. a decline of na+ currents was also ...20082553115
[can flame silanization change dental alloy joints?]. 20082700822
salivary testosterone levels and the progress of puberty in the normal boy.salivary testosterone (st) levels were measured in 84 boys aged 7.3-16.2 from the edinburgh growth study. the correlation coefficient between matched plasma/saliva samples was 0.88. six samples were collected over the course of one day from 0900 to 2100 h each month in the majority of the children for 4 consecutive months. mean daily st levels showed a significant rise between each pubertal stage (genital (g) and pubic hair (ph]. the rise in st became more rapid once a mean testicular volume (mt ...20082605791
choledochal cysts in the adult.although choledochal cyst is generally considered a disorder of childhood, in approximately 20% of patients a cyst is first recognized in adult life. we reviewed nine adults who underwent operation for choledochal cyst from 1974-1985 at yale new haven hospital. presenting symptoms included: crampy right upper quadrant pain, jaundice, pruritus, cholangitis, pancreatitis, hepatomegaly, and elevated liver function tests. seven patients had undergone previous biliary surgery. the eight patients with ...20082980768
is etoposide injection a vesicant? 20082791480
is etoposide injection a vesicant? 20082791480
contact dermatitis. 20083527125
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