| immunological aspects of cell membrane adhesion demonstrated by porcine enteropathogenic escherichia coli. | | 1978 | 75179 |
| cell-mediated and humoral immunity to chick type ii collagen and its cyanogen bromide peptides in guinea-pigs. | cell-mediated immunity (cmi) to chick type ii collagen and its cyanogen bromide (cb) peptides was studied in guinea-pigs using cutaneous delayed hypersensitivity reactions. responses were largely independent of molecular conformation in animals immunized with either native or denatured collagen, and reactions obtained with cb peptides 8, 9, 10 and 12 suggested that sites in the central regions of collagen chains were recognized in cmi. antibodies to collagen were detected by haemagglutination an ... | 1978 | 75183 |
| mediation of cytotoxic functions by classes and subclasses of sheep antibody reactive with cell surface immunoglobulin idiotypic and constant region determinants. | sheep antibodies, reactive with either the idiotypic or constant region antigenic determinants of the immunoglobulin light chain on guinea-pig l2c leukaemic cells, were separated into igm and into the two subclasses of igg, igg1 and igg2. antibody of both igg subclasses inhibited the migration of l2c cells along plastic surfaces; igm was only weakly inhibitory. antibody of class igm and of subclass igg1 mediated complement cytotoxicity against the l2c cells whereas only that of subclass igg2 med ... | 1978 | 75184 |
| [fungus diagnostics in practice]. | for the practising dermatologist the following examinations for the diagnosis of a fungus infection are recommended: unstained and stained preparations, as well as cultural differentiation of the causative organisms. in case of a first negative culture of a cutaneous mycosis histological examination is advised. the section should be stained by the pas method. in all mycotic diseases of the skin, skin appendages and mucous membranes, which are resistant to therapy, an intracutaneous test with the ... | 1978 | 75199 |
| specific suppression of the immune response by a factor obtained from spleen cells of mice tolerant to human gamma-globulin. | an antigen-specific suppressive factor was extracted from spleen cells of mice made tolerant by injection of deaggregated human gamma-globulin (hgg). the active material could be prepared from t cells, obtained by passaging spleen cells through an anti-immunoglobulin column, although not from cells adherent to the column nor from spleen cells pretreated with anti-thy-1 serum and c. this factor was antigen-specific since it was retained on immunoadsorbents containing hgg, but not on columns coate ... | 1978 | 75224 |
| [use of the method of macrophage migration inhibition for titration of toxic activity in microbial fractions]. | | 1977 | 75324 |
| serologically defined specificities of the pig main histocompatibility complex (sl-a). | six antigens detectable by the complement-dependent lymphocytotoxic technique were determined in pigs by six groups of alloimmune sera. it was confirmed that these specificities are controlled by the main histocompatibility region (sl-a). serological and genetic studies showed that the given specificities (provisionally designated l1 to l6) form at least 6 haplotypes. in addition, family studies confirmed the linkaged between sl-a region and c blood group locus. maximum lod score values are in r ... | 1977 | 75700 |
| alterations in the ultraviolet absorption spectra of steroids upon binding to serum proteins. | difference spectra of progesterone-binding globulin (pbg) complexes with progesterone and testosterone were measured. the contributions of steroid and protein to the difference spectra were resolved by use of 5alpha-pregane-3,20-dione and dihydrotestosterone to compensate for the perturbation of pbg. the absorption spectra of seven bound steroids all showed increased extinction coefficients, sharpened absorption bands, a small blue shift, and an increased area implying an enhanced transition mom ... | 1978 | 75741 |
| [problems in cns...with special reference to immunology of experimental allergic encephalomyelitis (author's transl)]. | | 1977 | 75776 |
| evaluation of the health effects of benzene inhalation. | | 1977 | 75779 |
| high dose inhibition of the tryptophan peptide induced encephalitogenicity. | in a previous publication (immunol. comm. 3:219, 1974) a hypothesis was proposed that the high dose inhibition of encephalitogenicity in giunea pigs seen with the tryptophan peptide, phe ser trp gly ala glu gly gln arg, and not observed with the whole myelin basic protein which contains this sequence, was the result of competitive inhibition by non-encephalitogenic fragments of the tryptophan peptide produced in vivo possibly by exopeptidases. i present data which disagrees with this hypothesis. | 1978 | 75835 |
| prevention of experimental allergic encephalitis in guinea-pigs with spinal cord protein: optimum pretreatment schedules and appraisal of plausible mechanisms. | pretreatment of hartley guinea-pigs with three injections of 100 microgram of the purified bovine spinal cord protein, (scp), protected tham from clinical experimental allergic encephalitis (eae) when they were subsequently challenged with 50 microgram of purified bovine myelin basic protein (mybp) in freund's complete adjuvant (fca). the length of the optimum pretreated schedule was found to be 1 week and the animals were fully protected for 2 weeks. protection declined thereafter so that by 4 ... | 1977 | 75839 |
| stimulation and inhibition of macrophages prior to immunization with a hapten-carrier conjugate. | delayed hypersensitivity reactions and antibody-mediated reactions to the carrier and to the hapten have been studied in animals treated with bcg or/and trypan blue before immunization with a hapten-carrier complex. the results show that it is possible to induce, with bcg, at the beginning of the response, an antigenic competition between hapten and carrier moieties of the antigen molecule. macrophages which modulate the response to the hapten-carrier complex by acting both on t cells involved i ... | 1977 | 75840 |
| solubilized tumour-associated antigens of methyl-cholanthrene-induced mouse sarcomas. comparative studies by in vitro sensitization of lymph-node cells, macrophage electrophoretic mobility assay and transplantation tests. | | 1978 | 75857 |
| contamination of primary embryonic bovine kidney cell cultures with parainfluenza type 2 simian virus 5 and infectious bovine rhinotracheitis virus. | two different viruses were isolated from bovine embryonic cell cultures after two subcultures from the primary cells. one virus was identified as parainfluenza type 2 simian virus 5 (sv-5), and the other was identified as infectious bovine rhinotracheitis virus. six months later, stock cultures of pig kidney (pk-15) cells were found to be contaminated with sv-5 virus. we believe that the source of the sv-5 virus in the bovine cells was a cross-contamination from monkey kidneys during preparation ... | 1978 | 75889 |
| correlation with different immunotypes of gonococcal antigens associated with growth in vivo. | | 1978 | 75944 |
| identity of specific macrophage-active human lymphokines. | | 1978 | 76257 |
| [antigenic properties of chlamydia of different origins]. | | 1978 | 76284 |
| [resorption of colostral gamma-globulins and detection of antibodies to bact. rhusiopathiaesuis, s. cholerasuis and beta-hemolytic esch. coli in newborn pigs]. | traced was the resorption of colostral globulins and the production of antibodies against bacterium rhusiopathiae suis, s. choleraesuis, and beta-hemolytic escherichia coli organisms in newborn pigs. it was found that in the newborn pigs that had not yet started sucking there were no gamma-globulins and specific antibodies against the agents mentioned above. such were observed after the animals had begun to suck, the titers of antibodies reaching their peak levels by the 10th--15th hour (erysipe ... | 1977 | 76366 |
| plasmid borne virulence of enterobacter hafniae. | the strain classified as enterobacter hafniae has been isolated in a severe epidemy of porcine diarrhoea. its pathogenicity has been found to be cotransmissible with resistance to oxytetracycline when the strain was grown in a mixed culture with some nonpathogenic e. hafniae strains as well as with escherichia coli. toxinogenity seems to be responsible for virulence of the strain. | 1978 | 76419 |
| specific reaction of aloe extract with serum proteins of various animals. | we found that aloe extract contains a lectin-like substance which reacts with serum proteins of various animals. furthermore, in human serum 2 proteins, alpha2-macroglobulin and alpha1-antitrypsin, were shown to be reactive with aloe extract. | 1978 | 76572 |
| synergistic cytotoxic effects of antibodies directed against different cell surface determinants. | three antibody populations were raised in rabbits against surface antigens on guinea-pig l2c leukaemic lymphocytes: against idiotypic determinants on the lambda chain of the surface immunoglobulin, against c region determinants on the lambda chain, and against the surface antigens recognized by conventional anti-lymphocyte sera. complement and k-cell cytotoxicities effected by the antibodies on l2c cells were studied in vitro. in both cytotoxic systems mixtures of the antibodies revealed synergy ... | 1978 | 76604 |
| neuromuscular diseases that affect the eye. | | 1978 | 76612 |
| an improved timm sulphide silver method for light and electron microscopic localization of heavy metals in biological tissues. | modifications of the timm sulphide silver method for the demonstration of heavy metals are described. to improve the structural preservation of the tissues perfusion with a glutaraldehyde fixature is employed before perfusion with the sodium sulphide solution. for the subsequent staining for light and electron microscopy, procedures for plastic embedding, paraffin embedding and cryostat sectioning are presented. examples from several tissues are shown, including the pituitary, pancreas, intestin ... | 1978 | 76622 |
| indole reactions of mast cells and enterochromaffin cells related to fixations with and without aldehydes. | | 1978 | 76624 |
| comparison of two aqueous biphasic systems used for the partition of biological material. | two biphasic systems, both consisting of water, dextran and poly(ethylene glycol) but differing in the molecular weight of the latter polymer, mr = 35 000 (systems a) and 6000 (systems b), have been studied. the phase diagrams for the two systems at 20 degrees are compared. the partition of proteins influenced by salts and the viscosity of the phases are direct functions of the difference in composition between the upper and the lower phase as measured by the lengths of the tie-lines found for t ... | 1978 | 76632 |
| heterogeneity, polypeptide chain composition and antigenic reactivity of c3 nephritic factor. | | 1978 | 76663 |
| [serum protein fractionation by rivanol]. | | 1978 | 76739 |
| possible change of a recognition mechanism for determining encephalitogenicity. | | 1978 | 76744 |
| prostaglandin-synthesis inhibitors in prophylaxis of food intolerance. | prophylactic doses of aspirin, indomethacin, or ibuprofen prevented symptoms of food intolerance in five out of six patients who on several occasions had had acute gastrointestinal symptoms after the ingestion of specific foodstuffs. blood and stool prostaglandin e2 and f2alpha concentrations during unprotected challenge were consistent with the idea that these symptoms were mediated through prostaglandin release. prostaglandin-synthetase inhibitors may benefit some patients with specific food i ... | 1978 | 76847 |
| bioassay of cholecystokinin-pancreozymin in duodenal mucosa. | | 1978 | 76960 |
| antibiotics for legionnaires' disease. | | 1978 | 76963 |
| platelet-foreign surface interactions: release of granule constituents from adherent platelets. | the interaction of suspensions of washed pig platelets with nine artificial surfaces (glass, polystyrene, three segmented polyurethanes, and surfaces formed by coating glass with albumin, fibrinogen, gamma-globulin, and collagen) is reported. platelet adhesion and release from adherent platelets were measured via labeling with 51cr and 14c-serotonin. the apparatus was a couette flow device allowing observation of surface-platelet effects uncomplicated by transport or flow effects. using a two-le ... | 1978 | 77273 |
| development of new bleomycins with potential clinical utility. | | 1977 | 77339 |
| steroid--protein interactions--xxxviii. influence of steroid structure on affinity to the progesterone-binding globulin. | | 1978 | 77359 |
| clostridium difficile and the aetiology of pseudomembranous colitis. | bacterial isolates from 5 patients with pseudomembranous colitis (p.m.c.) were screened for toxin production. strains of clostridium from 4 patients produced in vitro a toxin similar to that found in p.m.c. faecal suspension. these were identified as c. difficile. use of the strains from 2 patients induced a fatal enterocolitis when inoculated orally into hamsters pretreated with vancomycin. the c. difficile that produced the toxin in vitro was then re-isolated from hamster caecal contents. thes ... | 1978 | 77366 |
| escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are non-invasive. | three enteropathogenic escherichia coli (e.p.e.c.) strains (o127:k63:h6, o128:k67:h2, and o142:k86:h6) isolated from outbreaks of infantile diarrhoea and one strain from the "normal" colonic flora (e. coli hs) of a healthy adult were fed in doses of 10(6), 10(8), and 10(10) organisms in nahco3 to adult volunteers. the strains, which had been stored for 7--9 years, gave negative results in sensitive tests for heat-labile (l.t.) enterotoxin (y-1 adrenal-cell test), heat-stable (s.t.) enterotoxin ( ... | 1978 | 77415 |
| low-dose calcitonin in paget's disease. | | 1978 | 77443 |
| immunocytology of luteinizing hormone-releasing hormone. | | 1978 | 77511 |
| [role of the autonomic nervous system in the pathogenesis of asthma]. | | 1978 | 77530 |
| natural and immune antibodies to rabbit erythrocyte antigens. | natural agglutinins to rabbit erythrocytes were found in all human sera studied. in the newborn, the antibodies were of igg class; in the 6-month-old infants they were mainly of igm class. older children and adults had both igg and igm antibodies. agglutinins to rabbit erythrocytes were also found in serum from fourteen of fifteen other species studied. the trichloroacetic acid extract from rabbit erythrocyte stromata (tca-preparation) contains at least three different antigenic determinants: on ... | 1978 | 77552 |
| specificity of fc-receptors on lymphocytes and monocytes for guinea-pig igg1 and igg2: phagocytosis of erythrocytes. | the capacity of guinea-pig igg1 and igg2 antibodies to induce lymphocyte (k-cell) mediated lysis or monocyte/macrophage mediated phagocytosis of erythrocytes was studied with both human and guinea-pig effector cells. for both species, induction of k-cell mediated lysis was restricted to igg2 whereas both igg1 and igg2 could induce monocyte/macrophage mediated phagocytosis. in competitive inhibition experiments, only complexed igg2 inhibited lysis mediated by k-cells. the results suggest that the ... | 1978 | 77554 |
| haptenic antibody induced by n-phthaloylated ox insulin in the hartley guinea-pig. | female hartley guinea-pigs were immunized with n-phthaloylated ox insulin (96% na1,nb1,nb29-triphthaloyl ox insulin) using h. pertussis as adjuvant. haptenic antibody, which was found in antisera taken 20 days after secondary immunization, was assessed for cross-reaction with a series of n-acylated ox insulins. cross-reaction readily occurred between haptenic antibody and the partial hapten-bearing antigens, na1-monophthaloyl and nb1-monophthaloyl ox insulins. the immunochemical data suggested t ... | 1978 | 77750 |
| delay in the development of the allergic response to metals following intratracheal instillation. | intracheal intubation with the soluble metal salts potassium dichromate (k2cr2o7) and nickel sulphate (niso4) causes a delay of up to 8 weeks in the development of delayed hypersensitivity to the specific agent. it is suggested that absorption of sensitizers by the respiratory route may, under certain circumstances, induce a state of specific immunological unresponsiveness, rather than necessarily lead to the development of a state of allergic sensitivity. | 1978 | 77847 |
| a hypothesis to relate the specificity of t lymphocytes and the activity of i region-specific ir genes in macrophages and b lymphocytes. | | 1978 | 77879 |
| prolonged survival of pig orthotopic heart grafts treated with cyclosporin a. | cyclosporin a was given to pigs receiving orthotopic cardiac allografts from donors mismatched at the major locus. median survival in 20 control pigs was only 6 days; in 5 pigs given cyclosporin a at 15 mg/kg on 3 days median survival was 22 days; and when 6 animals were given 25 mg/kg intramuscularly for 2 days and then orally median survival is greater than 68 days, with 4 animals still alive. | 1978 | 77948 |
| non-enterotoxin-producing, non-invasive enteropathogenic escherichia coli. | | 1978 | 78068 |
| transmission, from man to hamster, of creutzfeldt-jakob disease with clinical recovery. | | 1978 | 78232 |
| immunogenicity and antigenicity of soluble cross-linked enzyme/albumin polymers: advantages for enzyme therapy. | soluble cross-linked polymers of hog-liver uricase and an excess of either rabbit or dog albumin were injected repeatedly into rabbits in order to determine their antigenicity and immunogenicity. whereas the enzyme in its free form induces antibody production, homologous albumin polymerised with the enzyme renders the complex non-immunogenic and non-antigenic. dog-albumin/uricase polymers injected into rabbits induce antibody formation against the dog albumin but not against the uricase. the res ... | 1978 | 78296 |
| [immunochemical comparison of tryptophanyl-trna-synthetases]. | a fraction of immunoglobulins was isolated from the sera of rabbit immunised by a homogeneous beef pancreas tryptophanyl-trna-synthetase (trsase). the igg fraction was shown to inhibit the enzymatic activity during aminoacylation of yeast trnatrp and tryptophan activation. by using the radioimmunoadsorption technique, the interaction of igg was tested with trsaes from beef pancreas and identical enzymes from other sources (contained in the total preparation). beef liver trsase efficiently inhibi ... | 1978 | 78439 |
| negative staining of a non-haemadsorbing strain of african swine fever virus. | since the application of negative staining, preceded by fixation, prevents the disruption and distortion of the capsid of the african swine fever virus, improved contrast and evaluation of the appearance and size of virus particles in the electron microscope is possible and, in addition, the icosahedral shape of the virus is demonstrable. the mature virus particle contains at least 2 capsid layers and an outer envelope. | 1977 | 78480 |
| a new approach to the structural determination of glycoproteins and polysaccharides: anhydrous hf solvolysis. | from experiments with glycoproteins containing the glycopeptide linkages, arabinose-o-hydroxyproline and galactose-o-serine (plant cell wall glycopeptides), n-acetylgalactosamine-o-serine/threonine (pig submaxillary mucin), and n-acetyl-glucosamine-n-asparagine (fetuin), it is apparent that anhydrous liquid hf, a reagent commonly used by snythetic peptide chemists for the complete removal of protecting groups from synthetic peptides, cleaves the o-glycosidic linkages of neutral sugars in 1 hr at ... | 1978 | 78502 |
| major transplantation antigens of pig kidney and liver. comparisons between the whole organs and their parenchymal constituents. | we have previously shown that cultured renal and hepatic parenchymal cells of the pig differ in the expression of major transplantation antigens. antigens apparently analogous to those of the mouse i region were detectable on kidney and some peripheral blood lymphocytes but not on liver, platelets, or other peripheral blood lymphocytes. the present study confirms these findings for liver parenchymal cells and for a mixture of kidney tubules and glomeruli prepared from fresh, perfused whole organ ... | 1978 | 78552 |
| [isolation and analysis of encephalitogenic fractions of spinal cord proteins]. | main encephalitogenic protein was isolated from bovine medulla spinalis and separated into homogenous polypeptide fractions by gel filtration; some of these fractions had the high encephalitogenic activity. the main protein and its fractions, possessing the encephalitogenic activity, caused a development of cross-reacting antibodies and a sensitization to intracutaneous administration of encephalitogenic preparations in animals. non-encephalitogenic main protein sensitized animals only to this p ... | 1978 | 78578 |
| [use of the immunofluorescence method for the diagnosis of cytomegalovirus infection]. | the method of immunofluorescence for diagnosis of cytomegalic infection vitally and in cases of fatal outcomes of the infection is proposed. recommendations for the preparation of anticytomegalovirus immune sera for an indirect modification of the method are presented alongside with the characteristics of procedure for the immunofluorescent analysis of cytomegalovirus. the clinico-laboratory diagnostic studies have demonstrated certain advantages of the proposed method over virus isolation from ... | 1978 | 78591 |
| [effectiveness of the tularemia-antibody erythrocyte diagnostic agent for the detection of specific antigen and antibodies to it]. | the authors demonstrated the efficacy of utilization of tularemia antibody erythrocytic diagnostic agent. data are presented indicating a strict specificity and a high sensitivity of this diagnostic agent for detection of the vi-antigen both in the tularemia microbe cultures and in the suspensions of the organs of rodents which perished of tularemia, irrespective of the state of cadaver. there was revealed relationship between the sensitivity of the diagnostic agent and the virulence of the tula ... | 1978 | 78604 |
| [quantifiable morphokinesis on parts of the hypothalamo-adenohypophyseal-gonadal axis of hormonally castrated boars. i. studies on boars treated with chlormadinone acetate]. | a clearly morphokinetic effect was recorded from the parts of the hypothalamo-adenohypophyseo-gonadal axis in boars that had been treated with chloromadinone acetate (cap). luteinising hormone release is inhibited by cap, which is reflected in an increase of luteinising hormone cells in their storage form. this leads to statistically significant decline in androgenic testicular tissue percentage and in the cell nucleus volumes of leydig's cells. excessive weight decrease of the testicle is cause ... | 1978 | 78696 |
| bovine fetus-specific serum proteins. purification and characterization of alpha1-fetoprotein and immunological identification of alpha2- and beta-fetoproteins. | bovine alpha1-fetoprotein was isolated from fetal calf serum by successive procedures of concanavalin a-sepharose chromatography, deae-sephadex chromatography, sp-sephadex chromatography and preparative disc polyacrylamide gel electrophoresis. the bovine alpha1-fetoprotein preparation was considered homogeneous by several physicochemical and immunochemical criteria. bovine alpha1-fetoprotein has a molecular weight of 68 000 with an amino acid composiotn similar to that of other mammalian alhpa1- ... | 1978 | 78727 |
| cellular immune response toward ms-2 phage and a synthetic fragment of its coat protein. | | 1978 | 78768 |
| [model of the interaction between trypsin and alpha 2-macroglobulin of porcine serum]. | a comparative study of the dissociation into subunits of porcine alpha2 m, either native or bound to trypsin (tn), has been carried out in order to determine the modifications of the alpha2 m structure due to the formation of the tn-alpha2 m complex. analytical ultra-centrifugation at ph 3.5 shows that the dissociation is smaller when alpha 2 m is bound to trypsin. electrophoresis in 4% polyacrylamide gels, in presence of 0.1% sds, of alpha2 m and tn-alpha2 m incubated in 1% sds leads to the sam ... | 1978 | 78773 |
| blood-group (a + h) fucolipids--a new group of complex glycosphingolipids. | | 1978 | 78860 |
| determination of virus-specific antigens in extracts from herpes simplex virus-infected cells by a cr release inhibition test. | a 51cr release inhibition test (crit) was developed for determining herpes simplex virus type 1 antigens in infected cell extracts. among the factors studied were the optimal concentrations of complement, antibody, and infected target cells. under standardized conditions, the relationship between antigen content and inhibition of chromium release was linear in a semilogarithmic plot, indicating that the antigen content can be determined from testing two dilutions of a given preparation. other te ... | 1978 | 78899 |
| comparison between the macrophage electrophoretic mobility (mem) and the fixed tanned erythrocyte electrophoretic mobility (fteem) tests in the detection of cancer. | when peripheral lymphocytes from patients with a history of cancer are incubated with encephalitogenic factor (ef), in 90% of cases the resulting products reduce the net surface negativity of guinea-pig macrophages, used as detector cells, as revealed in the macrophage electrophoretic mobility (mem) test. the mem test is positive in 36% of people with no history of cancer. formaldehyde-fixed tanned sheep erythrocytes have been used as detector cells in place of guinea-pig macrophages, in a fixed ... | 1978 | 78907 |
| streptococcal meningitis and pigs. | | 1978 | 79037 |
| (v.u.r. + i.r.r.) + u.t.i. = c.p.n. | | 1978 | 79091 |
| inhibitory effects of imidazolines on histamine liberation from human leukocytes and on tracheal smooth muscle tone. | antigen-induced ige-mediated release of histamine from human leukocytes, an in vitro model of allergic reactions, was blocked by imidazole and imidazole-compounds such as oxymetazoline and clonidine. the h-2-antihistamines antagonized this effect of imidazolines. alpha- and h-1-receptor blocking agents did not antagonize the effect. the contractile effects of the imidazolines were tested on tracheal preparations from the cow and guinea-pig. imidazole was found to be a rather potent contracting a ... | 1978 | 79298 |
| a colloidal iron silver impregnation method for acid mucopolysaccharide. | a simple and rapid method for the demonstration of acid mucopolysaccharide using colloidal iron, sulphosalicylic acid ammoniacal silver is described. satisfactory staining of human as well as animal tissue was obtained following 10% neutral formol saline fixation and paraffin sections. there were no oxidation or hydrolysis sequences. the staining specificity was controlled using methylation and saponification. the distribution of the acid mucopolysaccharide demonstrated by this method was identi ... | 1978 | 79306 |
| an in vitro method for studying the retrograde intra-axonal transport of horseradish peroxidase in sympathetic neurons. | | 1978 | 79433 |
| the human lt system. ii. immunological relationships of lt molecules released by mitogen activated human lymphocytes in vitro. | | 1978 | 79447 |
| cross-reactive idiotypic determinants on murine anti-(t,g)-a--l antibodies. | | 1978 | 79603 |
| definition and synthesis of the essential amino acid sequence for experimental allergic encephalomyelitis in lewis rats. | | 1978 | 79612 |
| mast cell in disease and its pharmacologic regulation. | | 1978 | 79621 |
| further studies on the mode of action of clostridium welchii type-d epsilon toxin. | intradermal injection of clostridium welchii type-d epsilon toxin increased the permeability of blood vessels in guinea-pig skin to evans blue dye by a mechanism not dependent on the release of histamine. the toxin was also found to raise the plasma concentration of cyclic adenosine 3', 5'-monophosphate in mice. it is concluded that epsilon toxin is an enterotoxin capable of causing widespread damage, after binding to receptor sites on the surface of certain cells, through a mechanism mediated b ... | 1978 | 79653 |
| a rapid method of spermatozoa staining for laboratory animals. | | 1978 | 79674 |
| isolation of an infectious agent from bone-marrows of patients with multiple sclerosis. | bone-marrow aspirates from 5 patients with recent episodes of multiple sclerosis (m.s.) contained increased numbers of plasma cells, and aspirates from 3 of these patients contained atypical reticulum cells. when bone-marrow from 4 of the patients was inoculated into cell cultures a cytopathic effect (c.p.e.) was observed, and this effect could be serially passaged to further cultures. the c.p.e. was not observed when ether-treated extracts of cells showing c.p.e. were used for passage or when t ... | 1978 | 79758 |
| [treatment of algodystrophic syndromes with calcitonin]. | a general account of algodystrophic syndromes is followed by the presentation of results obtained with 160 mrc u/day extracted pig or 100 mrc u/day synthetic salmon calcitonin in 95 patients with the most common form (sudeck's syndrome). clinical, biohumoral and radiographic data are reported. there was no difference in the response to the two products. excellent results were noted, first clinically and then radiographically. some radiographs are presented. | 1978 | 79988 |
| [some aspects of the control of atrophic rhinitis (author's transl)]. | the results obtained by a number of methods adopted in the control of atrophic rhinitis in herds in which this disease occurred, are reviewed. the long-term results may be described as disappointing. a number of possible causes of these disappointments are discussed. | 1978 | 80041 |
| pig histocompatibility antigens and beta2-microglobulin. | | 1978 | 80049 |
| [sensitivity of microorganisms isolated from swine to aqueous and proteinic solutions of gentamycin]. | employing a microbiologic method (in vitro) the activity was investigated of gentamicin dso pharmachim, dissolved in water, in normal swine gamma-globulin, and in normal swine polyglobulin with regard to swine strains of escherichia coli, salmonella choleraesis bordetella bronchiseptica, and pseudomonas aeruginosa as well as mycoplasms. a strong sensitivity was found to exsist in all tested strains (except for the mycoplasms) to gentamycin both in a water and in a protein solution. the in vivo t ... | 1978 | 80055 |
| the langerhans cell: its origin, nature, and function. | this is the biography of a cell--a cell as elusive and as deceiving as any in medical literature. this is the biography of the langerhans cell, literally a cell at our fingertips, yet seemingly always beyond our intellectual grasp. here is the story of a foundling within our epidermis, yet outside our pathologist's daily view. it is the history of a cell whose stain and form belied its function. it is a biography of a cell which virtually hid from us until it came under the revealing beam of the ... | 1978 | 80092 |
| studies of histamine release from pig lung in vitro induced by extracts of hemp dust [proceedings]. | | 1978 | 80120 |
| heparin-related immune thrombocytopenia. studies of antibody-heparin specificity. | | 1978 | 80131 |
| [comparative immunochemical and physico-chemical study of the specific beta-globulins of pregnancy]. | | 1978 | 80241 |
| [the effect of early appearing extrasystoles on systemic and coronary circulation]. | in 10 anaesthesized dwarf pigs with an open thorax the effects of extrasystoles on systemic and coronary circulation were investigated. the actual effect of an extrasystole depends on the time of its onset. early extrasystoles hamper the cardiac blood perfusion, with decreases in the stroke volume, mean arterial pressure, coronary blood flow, and elevation of coronary resistance. extrasystoles setting on later are of minor haemodynamic and coronarodynamic importance. the effects of bigeminy and ... | 1978 | 80301 |
| nature of the phosphotungstic acid-chromic acid (pacp) stain for plasma membranes of plants and mammalian sperm. | the selective staining of plasma membranes of plants and porcine spermatozoa given by a mixture consisting of 1% phosphotungstic acid in 10% chromic acid (pacp) applied following periodic acid destaining of glutaraldehyde-osmium tetroxide-fixed electron microscope sections is reduced or eliminated by prior extraction of the tissues with lipid solvents, including ethanol. the ethanol-soluble fraction of sperm contains constituents which restore the pacp-staining reaction when added to ethanol-ext ... | 1978 | 80336 |
| cholera toxin effects on fluid secretion, adenylate cyclase, and cyclic amp in porcine small intestine. | the effects of cholera toxin on mucosal cyclic nucleotide concentrations and on net fluid secretion in the porcine small intestine are reported. cholera toxin causes net secretion of fluid into the small intestine of weanling pigs, and secretory rates are dependent on the dose of the toxin placed in intestinal loops. intestinal secretion due to cholera toxin exposure was not consistently accompanied by elevated concentrations of mucosal cyclic amp or cyclic gmp. net fluid fluxes in individual lo ... | 1978 | 80378 |
| lymphocyte-mediated activation of fibroblast proliferation and collagen production. | among the many activities of antigen-triggered lymphocytes may be the control of fibroblast function. thymus-dependent lymphocytes challenged with the specific antigen, dinitrophenylated ovalbumin or tetanus toxoid produced a nondialyzable factor(s) capable of causing dermal fibroblasts to undergo dna synthesis. these fibroblasts, which exhibit basal proliferative levels in the absence of serum, responded to the lymphocyte factor with maximal thymidine incorporation at 48 to 72 hr. in addition, ... | 1978 | 80435 |
| the correlation of bacteriophage types of mycobacterium tuberculosis with guinea-pig virulence and in vitro-indicators of virulence. | among 58 isoniazid-sensitive strains of mycobacterium tuberculosis from india, burma and east africa, 23 were of phage type a, 31 of type i (intermediate), 4 of type b and none of type c. type i strains differed from type a strains in being attenuated in the guinea-pig, susceptible to h2o2, sensitive to thiophen-2-carboxylic acid hydrazide and resistant to thiacetazone and p-aminosalicylic acid; the content of strongly acidic lipids and of sulphatide lipids was low and the attenuation indicator ... | 1978 | 80440 |
| a direct plaque assay for hog cholera virus. | direct plaque formation with representative strains of hog cholera virus (hcv) has been obtained using several pig kidney cell lines under agar overlay. hcv-infected cells appear as hazy plaques when viewed against an indirect light source, and as white plaques after neutral red staining. hcv assay by direct plaque procedure is rapid and convenient and gives infectivity titres identical to the fluorescent focus assay technique. | 1978 | 80444 |
| endocarditis with an acid-fast organism after porcine heart-valve replacement. | | 1978 | 80620 |
| search by immunofluorescence for antigens of rotavirus, pseudomonas maltophilia, and mycobacterium kansasii in crohn's disease. | crohn's-disease tissue was tested by indirect immunofluorescence for antigens of rotavirus, pseudomonas maltophilia, and mycobacterium kansasii. no reactions were obtained with anti-serum to p. maltophilia and m. kansasii, and a granular fluorescence seen with rotavirus antibody was probably non-specific. | 1978 | 80631 |
| studies on myelin proteins in human peripheral nerve. | the myelin fraction from human peripheral nerve was prepared. two basic protein fractions (bf-p2 and pb) were isolated from acid extracts of the myelin fraction and three glycoproteins (br-po, pasii and y protein) were purified from its acid-insoluble residue. in biochemical analysis the human bf-p2 protein (m.w.13,000) showed similar but not identical properties to bovine bf-p2 protein. the pb fraction was suggested to include the encephalitogenic cns-bp (m.w.18,000) and another, new protein of ... | 1978 | 80952 |
| expression and function of idiotypes of lymphocytes. | | 1978 | 80953 |
| [effect of diethylcarbamazine in experimental anaphylaxis]. | | 1978 | 80960 |
| [antigenic relations between human papilloma viruses (hpv): experimental study in guinea-pigs (author's transl]. | a study of specific immune response in guinea-pigs after immunization with human papilloma viruses (hpv) purified from plantar warts, hand warts and condyloma acuminata is reported. the respective viruses induced the production of high antibody titres as well as specific cellular immunity as demonstrated by intradermal tests in all the animals. formalin-inactivated hpv gave similar results. the antigenic cross reactions between the different viruses were evaluated by immunofluorescence and immun ... | 1978 | 80972 |
| study of the tyrosyl residues of fumarase with tetranitromethane [proceedings]. | | 1978 | 80996 |
| antigenic relationship of the feline infections peritonitis virus to coronaviruses of other species. | utilizing the direct and indirect fluorescent antibody procedure, the antigenic relationship of the feline infectious peritonitis virus (fipv) to 7 other human and animal coronaviruses was studied. fipv was found to be closely related to transmissible gastroenteritis virus (tgev) of swine. transmissible gastroenteritis virus and fipv were in turn antigenically related to human coronavirus 229e (hcv-229e) and canine coronavirus (ccv). an interesting finding in the study was that the 8 coronavirus ... | 1978 | 81044 |
| [the distribution of soluble substances after application to the cerebello-medular cistern (author's transl)]. | | 1978 | 81047 |
| serum degradation of myelin basic protein with loss of encephalitogenic activity: evidence for an enzymatic process. | | 1978 | 81109 |
| gut endocrinology: correlation of physiology and morphology. | the gastrointestinal tract is a large and complex endocrine organ. elucidation of its nature, and the actions of its individual hormonal components, has advanced in recent years following the purification and sequencing of six probable hormones and the subsequent development of radioimmunoassay techniques for their measurement and immunocytochemistry for the determination of their cellular origin. immunoassay and immunocytochemistry are clearly complimentary to each other in providing a fuller u ... | 1976 | 81114 |