| [a survey of q fever at the shore of lake aibi, boertala area, xinjiang autonomous region]. | | 1984 | 6536371 |
| [rickettsiosis and chlamydiosis in hoggar (republic of algeria): epidemiological sampling]. | the study was made on reservoirs of infections (rodent, sheep, goat, dromedary), vectors (louse) and human-receptors. examinations were made on smears examined with staining and indirect-fluorescente techniques and on sera examined by complement fixation test. chlamydia psittaci appears very often in rodent, sheep, goat, dromedary and man. antibodies against coxiella burneti were found present in sheep, goat but mainly in dromedary and less than 16 years old boys. two lice were carrier of ricket ... | 1984 | 6548418 |
| active transport of proline by coxiella burnetii. | the obligate intracellular rickettsia, coxiella burnetii, was shown to possess an energy dependent proline transport system which displayed a high degree of specificity and was highly dependent on ph. transport was maximal at ph 3.0 to 4.5, a ph range approximately that of the host cell phagolysosome where the agent replicates. transport was inhibited by the uncouplers carbonyl cyanide m-chlorophenylhydrazone and dinitrophenol, but not by sodium arsenite. in the presence of glutamate, a preferre ... | 1984 | 6549343 |
| [experience with vaccination of humans against q fever in czechoslovakia]. | | 1983 | 6616283 |
| "q" fever, a new fever entity: clinical features, diagnosis and laboratory investigation. | | 1983 | 6622891 |
| dermal granulomatous hypersensitivity in q fever: comparative studies of the granulomatous potential of whole cells of coxiella burnetii phase i and subfractions. | dermal granulomatous reactivity to q fever antigens in guinea pigs has been described as a model for vaccine reactions seen in previously sensitized humans. this model has now been applied to study the ability of subfractions of coxiella burnetii to produce granulomas. q fever organisms in phase i, trichloroacetic acid-soluble and -insoluble fractions, and the extract and residue of chloroform-methanol extraction were tested for their relative ability to elicit and immunize for dermal granulomat ... | 1983 | 6642669 |
| canine diseases of public health significance in nigeria. | a review of diseases of dogs of public health significance in nigeria is given based essentially on recent findings. the objective is to collate and inform the public of some zoonotic diseases which have been reported in owned and stray dog populations in nigeria so as to encourage better methods of pet health care delivery and control in the country. rabies, q fever, toxoplasmosis, brucellosis, salmonellosis, coccidiodomycosis, ring worm and helmithzoonotic parasites associated with ancylostomi ... | 1983 | 6642903 |
| contagious ecthyma in lambs and laboratory personnel. | contagious ecthyma, diagnosed in three lambs, was transmitted to two researchers having direct contact with oral secretions from these lambs. intracytoplasmic viral particles were demonstrated by electron microscopy in gingival biopsies from one lamb. lamb to lamb transmission was most likely caused by use of a contaminated gavage feeding tube. concern for the effects of this disease and q fever on patients having contact with contaminated medical researchers prompted the formulation of safety g ... | 1983 | 6645395 |
| mosquito inoculation technique for the diagnosis of q fever employing an animal model. | | 1983 | 6654408 |
| abortion and stillbirth associated with chlamydia psittaci var ovis in dairy goats with high titers to toxoplasma gondii. | during two consecutive breeding seasons in a brucellosis-free dairy goat herd, approximately 40% to 70% of the does (mean herd size, 14.5) had stillbirths or aborted. none of the does aborted or had stillbirths twice. in the first breeding season, 9 of 13 does aborted in the last 2 months of gestation. three fetuses and 2 fetal placentas from 2 does were examined. microscopic findings included severe multifocal hepatic necrosis, mild pneumonia, and mild multifocal necrosis in the brain. cultures ... | 1983 | 6654724 |
| endocarditis due to q fever in nova scotia: experience with five patients in 1981-1982. | q fever endocarditis is rarely reported in north america; only four cases have been documented since 1953. in 1981-1982, five cases were identified in the victoria general hospital, halifax, nova scotia. four patients were from widely separated areas of nova scotia and one was from prince edward island. four patients with long-standing valvular abnormalities, including two with prosthetic valves, presented with recurrent febrile episodes. the fifth patient, who was previously well, had recurrent ... | 1983 | 6655300 |
| cardiac valve replacement in patients with active infective endocarditis. | since the introduction of effective antimicrobial therapy, the leading cause of death in patients with infective endocarditis is no longer sepsis but, rather, congestive heart failure. the mortality is higher in patients with severe heart failure due to infective endocarditis who are treated with medical therapy only than in those who additionally undergo cardiac valve replacement. the mortality is also higher in patients with severe heart failure due to aortic infective endocarditis (40 to 93%) ... | 1983 | 6662478 |
| [dynamics of the humoral immunity indices in laboratory animals multiply infected with coxiella burnetii]. | | 1983 | 6670107 |
| [microagglutination with rickettsia of q fever]. | | 1983 | 6675859 |
| elisa in the q fever diagnosis. | | 1983 | 6678571 |
| antibody-dependent cellular cytotoxicity of coxiella burnetii-infected j774 macrophage target cells. | cell-mediated immunity is clearly the critical host defense mechanism against human coxiella burnetii infection (q fever); the role of specific antibody is unclear. by using a mouse macrophage tumor cell line, j774, persistently infected with c. burnetii phase i organisms, in a standard 51cr-release cytotoxicity assay, we explored the possibility that antibody-dependent cellular cytotoxicity may be immune mechanism in q fever. after 16 h of incubation in the presence of immune sera from q fever ... | 1984 | 6690402 |
| chronic q fever. | | 1984 | 6699410 |
| prolonged q fever associated with inappropriate secretion of anti-diuretic hormone. | a man with acute q fever developed hyponatraemia associated with inappropriate secretion of anti-diuretic hormone. the pyrexial illness lasted for 9 weeks and failed to respond to tetracycline, erythromycin and intravenous lincomycin. subsequently seroconversion indicated chronic q fever. | 1984 | 6699416 |
| q fever: hazard from sheep used in research. | the recent recognition that q fever is endemic in ontario and the known occupational risk of q fever to research personnel working with sheep prompted a study to determine the prevalence of antibodies to the causative organism, coxiella burnetti, in animals and staff at a toronto animal research institute. of 37 sheep 34 (92%) were found to be seropositive--that is, to have a titre of complement-fixing antibody to the phase ii antigen of 1:8 or greater. of 331 staff members tested, 18% were foun ... | 1984 | 6704847 |
| seroepidemiology of q fever in nova scotia and prince edward island. | the prevalence of coxiella burnetti infection (q fever) was determined among nova scotia (n.s.) and prince edward island (p.e.i.) blood donors by using the complement fixation and microimmunofluorescence (if) test. the complement fixation and if antibody tests measured antibody prevalence for the phase ii or phase i and ii antigens, respectively. complement-fixing antibodies to phase ii antigen were detected in 4.1% of 997 n.s. and 5.0% of 219 p.e.i. blood donors. anti-phase ii antibodies were d ... | 1984 | 6713300 |
| [modification of antibody formation in animal experiments by glucocorticoids and aristolochic acid]. | in the bone marrow of guinea pigs a decrease of lymphocytes resulted after immunisation against q-fever antigen, compensating within 4 weeks. under treatment with prednisolone normalisation occurred within 3, with aristolochic acid as well as with prednisolone and aristolochic acid already up to the 2nd week. after immunisation plasma cell increase was lasting longer in the aristolochic acid group than in other groups. the antibody determinations resulted in different values. after immunisation ... | 1984 | 6719965 |
| [susceptibility of ornithodoros papillipes (argasidae) ticks to the rickettsia coxiella burnetii]. | a definition of susceptibility of an arthropod to an infectious or invasional agent is given. the susceptibility means a capacity of the arthropod for infection in a result of which the agent either completes a part of its life cycle in the organism of its invertebrate host or reproduces repeatedly in the organs and tissues of its internal medium causing or not causing a noticeable damage. on the model of the tick o. papillipes and q. fever agent there were shown differences in the resistance of ... | 1984 | 6728511 |
| [results of a study of q fever in odessa province]. | | 1984 | 6741363 |
| the role of the house fly (musca domestica l.) in the transmission of coxiella burnetii. | the flies which are fed a single rickettsia suspension keep their infectivity throughout their life and can contaminate environment as long as that. under conditions of experiment their life span is 32 days. coxiella burnetii survives in the faeces of flies as long as 80 days, in the dead flies as long as 90 days. | 1984 | 6745799 |
| [udder colonization with coxiella burnetii in cattle q fever]. | | 1982 | 6756861 |
| [elaboration and trial of an erythrocyte immunoglobulin diagnostic preparation for detecting coxiella burnetii]. | | 1981 | 6764963 |
| development and characterization of high-titered, group-specific fluorescent-antibody reagents for direct identification of rickettsiae in clinical specimens. | rabbits were inoculated with purified antigen preparations of coxiella burnetii and representative species of the spotted fever and typhus groups of rickettsiae. their antibody responses were monitored by complement fixation tests; high-titered antisera were fractionated with ammonium sulfate and then labeled with fluorescein isothiocyanate by the dialysis method. the conjugates had homologous 3+ staining titers of 1:256 to 1:2,048 and did not exhibit nonspecific staining. the rickettsia rickett ... | 1980 | 6769955 |
| seroprevalence of brucellosis and q fever in dairy animals. | | 1980 | 6781180 |
| fatty acid composition of rickettsiae. | the fatty acid compositions of selected strains of rickettsiae were studied by gas-liquid chromatography. the profiles of all the rickettsiae except coxiella burnetii were qualitatively similar. the fatty acid composition of c. burnetii was similar to that of certain legionella species. | 1981 | 6787071 |
| an abattoir survey of diseases of feral goats. | caseous lymphadenitis was the most frequently encountered pathological condition in 3,720 feral goats examined during routine meat inspection procedures. among 9 separate consignments of animals, the prevalence of infection averaged 7.4% (range 0.3% to 18.8%). the majority of lesions were seen in lymph nodes draining superficial body areas although many also occurred in internal nodes and organs. corynebacterium ovis was isolated from 25 of 32 lesions submitted for bacteriological examination. o ... | 1981 | 6805455 |
| fatal, acute non-a, non-b hepatitis with confluent necrosis. case report and proposal for diagnostic work-up. | we are reporting a fatal case of acute non-a, non-b (nanb) hepatitis with massive liver destruction in a 58-year-old woman. nanb hepatitis is still a diagnosis by exclusion, and detailed knowledge of the endemic diseases associated with hepatitis in a given geographic area should be included in the diagnostic work-up. in lebanon, where 97% of the adult population has anti-hav in their sera, the igm fraction of anti-hav must be determined in order to differentiate between previous exposure to hav ... | 1982 | 6809637 |
| experimental model for dermal granulomatous hypersensitivity in q fever. | q fever has been associated with granulomatous changes in clinical biopsy material obtained from liver and bone marrow. local reactions to skin testing have been described in previously sensitized humans, but histological studies of such reactions have not been reported. we note that delayed hypersensitivity reactions to whole-cell phase i q fever vaccine in immunized guinea pigs have a time course of development of induration characteristic of granulomatous hypersensitivity. histological examin ... | 1983 | 6822420 |
| intracellular fate of phase i coxiella burnetii in guniea pig peritoneal macrophages. | cultivated guinea pig peritoneal macrophages were infected with radio-labeled phase i coxiella burnetii in order to assess the intracellular distribution of ingested rickettsiae. localization of organisms was determined by fractionation of macrophage homogenates by equilibrium density centrifugation on sucrose gradients. macrophages isolated from either nonimmune or immune guinea pigs and infected with c burnetii opsonized with immune serum yielded equilibrium density distribution for rickettsia ... | 1983 | 6842464 |
| lysosomal response of a murine macrophage-like cell line persistently infected with coxiella burnetii. | the lysosomal response of a murine macrophage-like tumor cell line (j774) during persistent infection with coxiella burnettii was examined. by using acid phosphatase as a lysosomal marker, it was shown that phagosome-lysosome fusion occurred in j774 cells persistently infected with c. burnetii. this observation was verified using thorium dioxide, an electron-dense compound that is sequestered in secondary lysosomes. the phagolysosomes contained viable replicating rickettsiae. spectrofluorometric ... | 1983 | 6852916 |
| [experiences and recent data on coxiella burnetii infection (q fever). 1]. | | 1983 | 6857638 |
| [continuous multiplication of coxiella burnetii through persisting infection in buffalo-green monkey (bgm) cell cultures]. | | 1983 | 6858466 |
| [q fever. apropos of 13 case reports]. | | 1983 | 6865556 |
| [experiences and current knowledge of coxiella burnetii infection (q fever). 2]. | | 1983 | 6868062 |
| chronic or fatal q-fever infection: a review of 16 patients seen in north-east scotland (1967-80). | sixteen patients with serologically proven q-fever infection are reviewed. fifteen had significantly raised antibody titres to both phase i and phase ii coxiella burneti antigens, indicating persistent or chronic infection. one patient, a premature infant who died, had raised phase ii titres only, but is included together with the mother who had chronic q-fever and was the presumed source of infection. chronic q-fever infection has previously been regarded as virtually synonymous with q-fever en ... | 1983 | 6878620 |
| [how widespread is q fever in switzerland?]. | there are very few reports in the literature on mass seroepidemiological studies of the prevalence of q fever antibodies. those to be found are mostly concerned with focal epidemics of q fever. out of more than 2000 serum specimens from blood donors analyzed at random in switzerland in 1982 for q fever antibodies, 3.5% gave seropositive results (cbr titer at least 1:10). in selected population samples, e.g. forestry workers or vets, the prevalence was distinctly higher (7.6% and 25.7%). contact ... | 1983 | 6879140 |
| [q fever in pregnant women and its effect on the fetus and newborn infant]. | | 1983 | 6881465 |
| q fever--an enigma. | | 1983 | 6883060 |
| [seroprevalence of q fever in an endemic area of southern germany]. | in a random study among inhabitants of a village in a region of south germany in which q fever is endemic, seroprevalence and the significance of known risk factors for q fever were investigated. of the 1150 inhabitants, 948 (older than 14 years, resident in the endemic region for more than six months) were included in the study (target group). within eight months 715 subjects (total group) were actually tested. the total group did not differ from the target group demographically. there were 136 ... | 1983 | 6884215 |
| serological evaluation of o fever in humans: enhanced phase i titers of immunoglobulins g and a are diagnostic for q fever endocarditis. | serological parameters were compared in 15 cases of coxiella burnetii infection comprising 5 cases each of primary q fever, chronic granulomatous hepatitis, and endocarditis. the diagnosis was made on the basis of clinical history and serology and on the isolation of c. burnetii phase i from biopsy specimens of liver and bone marrow from two patients with granulomatous hepatitis and from the aortic valve vegetations of five patients with endocarditis. the temporal sequences of immunoglobulin lev ... | 1983 | 6885155 |
| serological study with rickettsial antigens in erythema chronicum migrans. | 21 sera of 13 patients with erythema chronicum migrans (ecm) and related diseases were examined for the presence of antibodies against 14 rickettsial antigens by using 3 serological techniques in 2 laboratories. most tests were negative. this indicates that ecm and related diseases are not due to an hitherto known rickettsia. 5 out of 158 tests showed, however, positive reactions in low titers against rickettsia akari and coxiella burnetii. thus, an antigenic relationship may exist between one o ... | 1981 | 6895877 |
| q fever control measures: recommendations for research facilities using sheep. | q fever (query fever) is a zoonosis caused by the rickettsia coxiella burnetii. domestic ungulates such as sheep, cattle, and goats serve as the reservoir of infection for humans and shed the desiccation-resistant organism in urine, feces, milk, and especially in birth products. in humans the illness is generally mild; however, q fever hepatitis is often seen and q fever endocarditis is an uncommon, but frequently fatal complication. q fever long has been recognized as an occupational hazard amo ... | 1982 | 6924645 |
| biochemical stratagem for obligate parasitism of eukaryotic cells by coxiella burnetii. | coxiella burnetti, the etiologic agent of q fever, is an oligate intracellular parasite of eukaryotes. unlike the majority of successful bacterial parasites, which escape the bactericidal environment of the phagolysosome by various means, c. burnetii multiplies only in the phagolysosome. in view of the relatively harsh environment inhabited by c. burnetii, we have examined (i) the in vitro metabolism of glucose and glutamate by whole cells of c. burnetii under conditions designed to approximate ... | 1981 | 6942430 |
| q fever endocarditis. | despite a worldwide distribution of coxiella burnetii, only single cases of q fever endocarditis have been reported outside great britain and australia. we present 10 patients; five were female, only four had a history of environmental exposure, and the mitral valve was involved as commonly as the aortic stenosis, and three patients had a prosthetic valve. we confirm the importance of hepatic involvement, thrombocytopenia and hypergammaglobulinemia as diagnostic features. diagnosis was establish ... | 1982 | 6977271 |
| rickettsioses: a continuing disease problem. who working group on rickettsial diseases. | the rickettsioses continue to constitute major health problems in many areas of the world. unlike those diseases that are transmissible directly from man to man, the rickettsioses are closely associated with man's environment and are therefore difficult to recognize and require complex strategies for their control. this article is concerned mainly with means for recognition and surveillance of these diseases, since only with reliable background information can a reasonable strategy for preventio ... | 1982 | 6980728 |
| immunogenicity and reactogenicity of a q fever chemovaccine in persons professionally exposed to q fever in czechoslovakia. | an immunization trial carried out on 1310 persons professionally exposed to q fever confirmed the suitability of a chemovaccine for field use. its immunogenicity and reactogenicity differed in three groups of subjects who differed in their previous experience of q fever and who were given different lots of the vaccine. there was some correlation between reactogenicity of the vaccine and pre-immunization positivity in the microagglutination and skin tests as indicators of a previous exposure. the ... | 1982 | 6982774 |
| q fever in india: a review. | | 1980 | 7005351 |
| [survival capacity of chlamydiae and coxiella burnetii under environmental conditions (author's transl)]. | | 1980 | 7006982 |
| validation of legionella pneumophila indirect immunofluorescence assay with epidemic sera. | sera from six outbreaks of legionellosis and four outbreaks of pneumonia of other etiologies were tested with the indirect immunofluorescence assay (ifa) as currently performed. the current ifa is at least as sensitive as the original test in detecting cases of legionnaires disease (78 to 91%). by using center for disease control criteria for a positive (fourfold increase in titer during convalescence to greater than or equal to 128) or presumptive (single titer greater than or equal to 256) ser ... | 1981 | 7007417 |
| prevalence of rickettsial antibody and cell-mediated reaction in cynomolgus monkeys (macaca fascicularis). | serologic studies on feral, colony-held cynomolgus monkeys indicated that 61% reacted to coxiella burnetii antigens, and 36% reacted to rickettsia conorii antigens. the results suggest that a high percentage of cynomolgus monkeys have been exposed to these organisms. | 1980 | 7007722 |
| q fever in finland: clinical, immunological and epidemiological findings. | clinical, immunological and epidemiological features of 14 human cases of q fever diagnosed at aurora hospital are presented. all patients had an acute febrile disease and 9 (64%) had respiratory symptoms, 4 (29%) verified pneumonia, and 9 (64%) hepatitis, which in 4 biopsied cases proved to be granulomatous. presence of circulating immune complexes was shown in 10/11 patients investigated by the platelet aggregation test (pat) and the platelet iodinated protein a (pipa) test. q fever is not kno ... | 1981 | 7017906 |
| [serological studies in bovine q fever]. | a serologic study was carried out by means of the complement-fixation test (cft) and the immunofluorescence titration method (itm) of a total of 1250 blood samples from 13 farms, having records of abortions, retention of placentae, and endometritis. the comparison of cft and itm results showed that 44 (52.3 per cent) of the positive sera were altogether positive by the two methods, 24 (28.6 per cent) sera yielded positive reactions by cft and negative ones by itm, and 16 (19 per cent) sera prove ... | 1981 | 7029885 |
| q fever as an occupational illness at the national institutes of health. | | 1982 | 7036198 |
| decreasing prevalence of q fever in illinois. | there were 858 (37.7 percent) q fever-infected dairy herds among the 2,277 tested in illinois in 1963. the percentage decreased to 19.2 percent (380 of 1,975) in 1967. reaction rates (complement-fixation test titer of 1:8 or greater) in serum samples from veterinarians decreased from 13.3 percent in 1956 to 3.9 percent in 1964 and from 3.6 percent in 1966 to 0 percent in 1968, 1970, 1972. there were 14 (2.7 percent) reactive serum samples among 526 abattoir workers tested in 1966; reaction rates ... | 1982 | 7063599 |
| biological and immunological properties of coxiella burnetii vaccines in c57bl/10scn endotoxin-nonresponder mice. | vaccines prepared from formalin-killed whole cells of coxiella burnetii (ohio strain) or from chloroform-methanol residue (cmr) and extract (cme) of such cells were examined for biological and immunological properties in male c57bl/10scn endotoxin nonresponder mice. vaccines containing killed whole cells induced a high incidence of gross pathology, as evidenced by liver necrosis, significant splenomegaly, and significant hepatomegaly in mice. the degree and onset of these pathological changes we ... | 1982 | 7068212 |
| q fever hazards from sheep and goats used in research. | two recent outbreaks of q fever in research institutions prompted the authors to review extant data, in an effort to delineate hazards to humans from small ruminants used in research. prevalence of q fever antibodies was 24% among 2097 sheep and 57% among 1475 goats from various sources. in a facility using sheep for prenatal research, in which an epidemic of human q fever later occurred, antibody prevalence among sheep was 77%, with larger than usual proportions of high (greater than or equal t ... | 1982 | 7073323 |
| a preliminary report on serum enzyme changes in guineapigs infected with coxiella burnetii. | | 1982 | 7106889 |
| q fever: a study of 111 consecutive cases. | | 1982 | 7110006 |
| are viral studies indicated in juvenile-onset diabetes? | recent observations have shown that insulin-dependent diabetes (jod) may be the result of autoimmunity causing more or less rapid pancreatic isle cell destruction. this autoimmune process may be initiated in individuals who are genetically vulnerable to specific virus action. several viruses have been implicated as causing jod. rubella and mumps viruses were the first viruses to be proved diabetogenic. a few years ago coxsackie b viruses were added to the list. a prospective study of all new dia ... | 1982 | 7110740 |
| [q-fever epidemic in an institute of human pathology]. | at the institute of pathology of tübingen university 12 members of the staff (nine doctors, one secretary, one cleaner, and one autopsy assistant) fell ill with an influenza-like disease with high fever. in 11 instances there was positive serological evidence of q-fever. the post-mortem room assistant was not tested serologically, but the disease followed a typical course. all those who fell ill had taken part in post-mortem examinations or a case demonstration at the institute of pathology. sev ... | 1982 | 7117152 |
| [a case of q fever]. | | 1982 | 7135362 |
| [coxiella burnetii infection. apropos of 10 cases]. | | 1982 | 7144289 |
| [outbreak of q fever in a municipal abattoir]. | the present paper reports on a q fever outbreak of 149 cases in a municipal slaughter house focus. the diagnosis was established by clinical, epidemiological, radiologic and laboratory investigations. the route of transmission was air-borne from the sick animals (not detected at the veterinary control) to man. a closer cooperation is recommended between the human and veterinary health services, for early detection of the cases, their prevention and control. the authors suggest the need to immuni ... | 1982 | 7156694 |
| multiplication of coxiella burnetii in aedes aegypti. | | 1982 | 7174009 |
| serologic survey for certain zoonotic diseases in black bears in california. | black bears (ursus americanus) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases: toxoplasmosis (indirect hemagglutination), q fever (microagglutination), trichinosis (latex particle agglutination), botulism (passive hemagglutination), leptospirosis (plate agglutination), and plague (enzyme-linked immunosorbent assay). of 149 sera tested, 40 (27%) were positive for toxoplasma gondii antibodies and 25 (17%) had antibodies against coxiella burne ... | 1982 | 7174445 |
| [control of q fever]. | | 1982 | 7179235 |
| natural occurrence of coxiella burnetii in the brown dog tick rhipicephalus sanguineus. | | 1980 | 7191407 |
| [q-fever in dutch dairy cattle]. | | 1981 | 7207675 |
| [q fever in the etiology of spontaneous abortion]. | | 1981 | 7212210 |
| role of antibody in coxiella burnetii infection. | balb/c mice infected with coxiella burnetii phase i developed a state of acquired resistance which could be detected during week 2 postinfection. immune serum, administered to normal mice 24 h before challenge with c. burnetii, appeared to accelerate the development of resistance. an increased clearance rate could be measured in these serum recipients 1 week postinfection. simultaneous administration of immune serum and c. burnetii did not affect the normal clearance rate of rickettsiae from the ... | 1981 | 7216465 |
| efficacy of translation in the rickettsia coxiella burnetii. | the addition of coliphage q beta ribonucleic acid to a cell-free translation system obtained from coxiella burnetii cells caused the formation of monosomes and disomes from ribosomal subunits and resulted in synthesis of viral coat protein. rickettsial ribosomes and associated translation factors functioned together, with fidelity, efficiency, and a specificity similar to those of free-living gram-negative bacteria. | 1981 | 7217018 |
| a serological survey for evidence of q fever and in camels in nigeria. | | 1980 | 7225776 |
| lactoserological study for detection of q fever infection in freshly secreted bovine milk. | | 1981 | 7251105 |
| immunological and biological characterization of coxiella burnetii, phases i and ii, separated from host components. | coxiella burnetii, phase i and ii, cells cultivated in the yolk sac of chicken embryos were separated from host cell components by two cycles of isopycnic renografin gradient centrifugation. initial steps in the purification of viable c. burnetii involved differential centrifugation and sedimentation through an aqueous solution of 30% sucrose and 7.6% renografin. after the first, but not the second, cycle of renografin gradient centrifugation, the cells were passed through microfilter glass filt ... | 1981 | 7251150 |
| host-parasite interaction and development of infraforms in chicken embryos infected with coxiella burnetii via the yolk sac. | two phase i strains of coxiella burnetii of different virulence were injected into the yolk sacs of chicken embryos, and the yolk sacs and livers were examined at intervals by light, fluorescent, and electron microscopy. the high absorptive and digestive capacities of the yolk endoderm contributed to he entrance of the organisms into endodermal epithelial cells where c. burnetii multiplied. organisms multiplied not only inside specific vacuoles originating from phagolysosomes but also in the cyt ... | 1981 | 7251166 |
| a study on the reservoir status of q-fever in avifauna, wild mammals and poikilotherms in uttar pradesh (india). | fifteen species of free-living birds (pigeon, mynah, house-sparrow, crow, vulture, owl, swallow, parrot, heron, duck, guinea fowl, hawk, kite, dove and peacock), 11 species of small/large wild mammals (rat, bandicoot, house mouse, shrew, bat, mongoose, ant eater, jackal wild cat, chinkara and tiger) and 5 species of poikilotherms (snakes, python, tortoise, monitor and eel) were screened for evidence of q-fever infection by the capillary agglutination test on sera to detect antibodies and/or by a ... | 1980 | 7251266 |
| evaluation of a killed phase i coxiella burnetii vaccine in cynomolgus monkeys (macaca fascicularis). | the protective efficacy of a killed, purified, phase i coxiella burnetii vaccine was tested in cynomolgus monkeys. monkeys vaccinated once with 30 micrograms of the antigen were challenged 6 or 12 months later with virulent phase i rickettsiae administered in small-particle aerosols. the vaccine provided only partial protection, since some of the challenged monkeys developed clinical signs of illness. however, the vaccinated animals did not develop pneumonia as determined by radiographic evaluat ... | 1981 | 7253550 |
| [acute q fever: study of 23 patients (author's transl)]. | twenty-three patients with q fever who were diagnosed over a 3 year period are described. the majority came from the madrid urban area and less than half had epidemiological antecedents. nine patients presented with pulmonary infiltrations, 12 with suppressed fever and in 2 criteria for fever of unknown origin were met. the majority had clinical or analytic data of hepatic disease and liver biopsy practiced in 4 patients showed granulomas. diagnosis was established through the increment of seric ... | 1981 | 7253757 |
| human milk as a source of q-fever infection in breast-fed babies. | | 1981 | 7262921 |
| fate of phase i and phase ii coxiella burnetii in several macrophage-like tumor cell lines. | several macrophage-like tumor cell lines of murine origin were exposed to phase i and phase ii coxiella burnetii, and the subsequent fate of the parasites was determined by electron and bright-field microscopy. phase i c. burnetii proliferated within and established a persistent infection of p388d1, j774, and pu-5-ir cell lines but not of wehi-3 and wehi-274 cell lines. phase ii c. burnetii, however, entered into and persistently infected all five cell lines. the parasites proliferated within va ... | 1981 | 7263063 |
| developmental cycle of coxiella burnetii: structure and morphogenesis of vegetative and sporogenic differentiations. | coxiella burnetii is a gram-variable obligate intracellular bacterium which carries out its development cycle in the phagolysosome of eucaryotic cells. ultrastructural analysis of c. burnetii, in situ and after renografin purification, by transmission electron microscopy of lead-stained thin sections has revealed extreme pleomorphism as demonstrated by two morphological cell types, a large cell variant (lcv) and a small cell variant (scv). potassium permanganate staining of purified rickettsiae ... | 1981 | 7275931 |
| cryptic epidemic of q fever in a medical school. | pregnant sheep used in perinatel research were the source of a large outbreak of q fever in 1980 among the faculty and staff of a medical school. complement-fixation tests with phase ii coxiella burnetii antigen were positive in 81 persons, of whom 58 (71.6%) had q fever during the first eight months of 1980. microagglutination and/or indirect immunofluorescence tests of 485 sera were positive in an additional 56 persons. only 41 of the 137 seropositive persons were involved in caring for or wor ... | 1981 | 7276623 |
| aerosol q fever infection of the nude mouse. | athymic nude mice and euthymic littermate controls were exposed to 10(4) coxiella burnetii organisms by small-particle aerosol. antibody response with and without 2-mercaptoethanol treatment of serum was determined at various intervals after infection and serial kills were done to determine morphologic changes in both mouse phenotypes. total antibody titers determined by the indirect fluorescent antibody technique to phase i and phase ii c. burnetii were identical for both groups of mice. microa ... | 1981 | 7281464 |
| q fever in cyprus: a short review. | | 1981 | 7306776 |
| [q fever (author's transl)]. | comparative analysis of two q fever epidemics in baden-württemberg demonstrated the following characteristics of this zoo-anthroponosis endemic in southern germany: 1. affected areas are situated along sheep tracks and natural concentrations of the dermacentor marginatus. 2. the disease spreads in waves. 3. it causes typical symptoms, particular an intense tension headache, and typical radiographic findings. men are more commonly and more severely affected than women. children are not affected d ... | 1981 | 7307989 |
| causes of pneumonia presenting to a district general hospital. | the incidence of bacterial, viral, mycoplasma, and rickettsial infections has been assessed prospectively in 210 adult patients with pneumonia who presented to a district hospital over a six-year period. one hundred and thirteen infective agents were detected in 103 patients. the agent most frequently detected was mycoplasma pneumoniae which accounted for 30 infections. a bacterial pathogen was found in 43 patients. streptococcus pneumoniae was the most common of these (24 patients); staphylococ ... | 1981 | 7314031 |
| [epidemiologic, serologic, clinical and therapeutic aspects of q fever endocarditis: report of two cases (author's transl)]. | | 1981 | 7321652 |
| legionnaires' disease: a review of the epidemiology and clinical manifestations of a newly recognized infection. | during the 2-year period 1977 through 1979, 26 patients with legionnaires' disease were seen at the mayo clinic and affiliated hospitals. the patients ranged in age from 17 to 81 years with a median of 51 years. twelve (46%) were immunologically compromised. most of the other patients had underlying chronic tobacco bronchitis. hectic fever, cough, and diarrhea were common symptoms. chest radiographs showed patchy perihilar infiltrates that often progressed to consolidation. diagnosis was made by ... | 1980 | 7354652 |
| q fever and raw milk. | | 1980 | 7358543 |
| [study of the titers of coxiella burnetii antibodies in a healthy population (author's transl)]. | | 1980 | 7366265 |
| q fever in the republic of ireland: an update. | | 1980 | 7372449 |
| [a patient with q fever pneumonia in the netherlands]. | | 1980 | 7374827 |
| environmental exposure to coxiella burnetii: a sero-epidemiologic survey among domestic animals. | the prevalence of agglutinating serum antibodies against coxiella burnetii, the cause of q fever in humans, was tested in a hospital population of companion animals and livestock in california during 1973--1975. a sample of stray dogs was also tested. among the hospitalized animals 346 (48%) of 724 dogs, 7 (9%) of 80 cats, 9 (32%) of 28 cattle and 31 (26%) of 121 horses had antibodies against c. burnetii. of 316 stray dogs 208 (66%) were seropositive. the overall prevalence of 53% among 1040 dog ... | 1980 | 7377186 |
| prevalence of human q fever in south kanara district, karnataka. | | 1980 | 7390589 |
| natural occurrence of coxiella burnetii in domestic mammals of karnataka state. | | 1980 | 7390590 |
| [study of the probable role of the agent of enzootic ovine abortion in infectious human pathology. preliminary report]. | 418 workers were surveyed at a meat-packing plant. the presence of complement-fixing antibodies to the causative agent of enzootic abortion of sheep (eas) was detected in 59 workers (14.27%), brucellosis in 32 workers (7.64%) and q fever in 5 workers (1.18%). eas antibodies were found to reach titers of 1 : 10 to 1 : 40 and higher, changing dynamically. the persons found to be seropositive belonged mainly to the workers of the sausage-making, slaughtering, intestinal, subproduct and skin-salting ... | 1980 | 7395400 |