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reproductive toxicity in mink (mustela vison) chronically exposed to environmentally relevant polychlorinated biphenyl concentrations.female mink were exposed to a technical polychlorinated biphenyl (pcb) preparation (clophen a50 [a50]; 0.1 or 0.3 mg/animal/d), one fraction of a50 containing the non- and mono-ortho-chlorinated congeners (0-1-ortho-chlorobiphenyls [cbs]), another fraction of a50 containing the congeners with two to four ortho-chlorines (2-4-ortho-cbs), or an organic extract from baltic gray seal blubber. the animals were exposed for 18 months, including two reproduction seasons. among the animals given the high ...200111596766
can--a pan-carnivore sine family.short retroposons or short interspersed elements (sines) constituting 5-10% genome have been isolated from various organisms. can sines initially found in american mink were named after dogs (canis), and the range of their distribution in the genomes of carnivores and mammals in general remained topical. here we demonstrate can sequences in representatives of all carnivore families, but not beyond carnivores, on the basis of sequence bank search and genomic pcr. analysis of their distribution su ...200211773970
productive infection of a mink cell line with porcine endogenous retroviruses (pervs) but lack of transmission to minks in vivo.porcine endogenous retroviruses (pervs) are considered a special risk for xenotransplantation because they are an integral part of the porcine genome and are able to infect cells of numerous species including humans in vitro. among these cells, the mink lung epithelial cell line mv1lu could be productively infected with perv. provirus integration was detected by pcr, expression of viral proteins was shown by immunostaining and reverse transcriptase was detected in cell supernatants. perv produce ...200211890525
the genome phylogeny of domestic cat, red panda and five mustelid species revealed by comparative chromosome painting and g-banding.genome-wide homology maps among stone marten (martes foina, 2n = 38), domestic cat (felis catus, 2n = 38), american mink (mustela vison, 2n = 30), yellow-throated marten (martes flavigula, 2n = 40), old world badger (meles meles, 2n = 44), ferret badger (melogale moschata, 2n = 38) and red panda (ailurus fulgens, 2n = 36) have been established by cross-species chromosome painting with a complete set of stone marten probes. in total, 18 stone marten autosomal probes reveal 20, 19, 21, 18 and 21 p ...200212067210
validation of a cell culture bioassay for detection of petroleum exposure in mink (mustela vison) as a model for detection in sea otters (enhydra lutris).to validate a luciferase bioassay, which is based on a recombinant mouse hepatoma cell line, for the detection of exposure to petroleum in mustelid species.200212118676
cdna cloning and molecular characterization of mink smad4.the smad family of proteins have been implicated as major components of the tgf beta signalling pathway and are important mediators of its pleiotrophic effects. here we describe the cloning and characterization of the mink (mustela vison) ortholog of smad4. mink smad4 has a high level of conservation to its human counterpart showing 96% homology at the dna level and 99% at the amino acid level. this is in agreement with the close homologies seen for the rat and mouse orthologs. in vitro transcri ...200212180137
directional left-sided asymmetry of adrenals in experimentally domesticated animals.directional left-sided asymmetry of the adrenals was typical of black and silver foxes, american minks, and gray rats selected by their behavior. in domesticated, but to a greater extent, in aggressive animals, the weight of the left adrenal and the width of its medulla and cortex markedly surpassed the corresponding parameters of the right adrenal. in aggressive animals enlargement of the left adrenal cortex was associated with widening of the zona reticularis, while in domesticated animals wit ...200212420075
comparative molecular cytogenetic studies in the order carnivora: mapping chromosomal rearrangements onto the phylogenetic tree.we have made a set of chromosome-specific painting probes for the american mink by degenerate oligonucleotide primed-pcr (dop-pcr) amplification of flow-sorted chromosomes. the painting probes were used to delimit homologous chromosomal segments among human, red fox, dog, cat and eight species of the family mustelidae, including the european mink, steppe and forest polecats, least weasel, mountain weasel, japanese sable, striped polecat, and badger. based on the results of chromosome painting an ...200212438790
relationship of the hormone-sensitive lipase-mediated modulation of cholesterol metabolism in individual compartments of the testis to serum pituitary hormone and testosterone concentrations in a seasonal breeder, the mink (mustela vison).the role of cholesterol differs in the two compartments of the testis. in the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. here we evaluate the hormone-sensitive lipase (hsl) modulation of the cholesterol metabolism in each compartment of the testis. two hsl immunoreactive bands of 104- and 108-kda were detected in western blots per ...200312604619
genetic map of the american mink: gene conservation and organization of chromosomes. 19873298154
the current and future management of wild mammals hunted with dogs in england and wales.there is increasing concern about the use of lethal methods to control wild mammal populations, especially those methods that may have significant impacts on animal welfare. the continued use of dogs to hunt wild mammals in england and wales, principally foxes (vulpes vulpes), red deer (cervus elaphus), brown hares (lepus europaeus) and mink (mustela vison), has become a focus for political debate and has been the subject of a recent uk government inquiry. this paper reports the results of a que ...200312654279
concentrations and hazard assessment of pcbs, organochlorine pesticides and mercury in fish species from the upper thames: river pollution and its potential effects on top predators.aquatic environmental contamination levels of organochlorine pesticides (ocps), polychlorinated biphenyls (pcbs) and heavy metals in the upper thames catchment area, uk were assessed on the basis of fish muscle analysis in wet weight, and their effects on top predators were assessed. the contamination levels of lead, cadmium, dichloro-diphenyl-trichloroethane (ddt) and its metabolites were found to be low (undetectable) in the area. average mercury contamination level varied between 55 and 342 m ...200312656245
susceptibility of mink (mustera vision)-derived cells to replication by human immunodeficiency virus type 1.in vivo studies for understanding viral transmission and replication, host immune responses, and pathogenesis of human immunodeficiency virus type 1 (hiv-1) infection would greatly benefit from the establishment of a small-animal model. in this study, we explored the potential of american mink (mustera vison) as a susceptible host. we found that primary cells and cell lines derived from this species efficiently supported trans-activation of the hiv-1 long terminal repeat by tat. accordingly, the ...200312692213
anatomical organization of the visual system of the mink, mustela vison.the organization of the retinogeniculocortical visual system of the mink was studied by anterograde and retrograde tracer techniques, by physiological mapping, and by direct recordings from axonal terminals after injection of kainic acid. in the lateral geniculate nucleus, retinogeniculate afferents are segregated according to eye of origin between the two principal layers, a and a1. within each of these layers there is a further parcellation according to functional type: on-center afferents ter ...19863016036
transmissible spongiform encephalopathies in non-domestic animals: origin, transmission and risk factors.the transmissible spongiform encephalopathies (tses), scrapie and bovine spongiform encephalopathy (bse), are serious diseases of domestic animals. although not as significant in terms of numbers of animals affected or geographical distribution, tses also affect non-domestic animals. transmissible mink encephalopathy (tme) was the first tse to be identified in non-domestic animals. this disease of captive mink (mustela vison) is very rare and is associated with exposure through feed contaminated ...200312793777
verrucous endocarditis associated with streptococcus bovis in mink (mustela vison).between 1998 and 2001, mortalities due to verrucous endocarditis were experienced at several mink farms. gram-positive cocci were isolated from the endocardium of all the animals examined but not always from other internal organs. almost all the isolates were identified as streptococcus bovis and only a few isolates belonged to other streptococcus species. typing by pulsed-field gel electrophoresis of a selection of isolates revealed several patterns and several different clones. attempts to rep ...200312974338
importance of sex chromatin in identifying placental type: a note of haemochorial placental type of the mink (mustela vison) and the dog (canis familiaris). 196414195055
mapping of 53 loci in american mink (mustela vison).fifty-three genes were mapped in the american mink genome using polymerase chain reaction (pcr)-based analysis of a chinese hamster-american mink somatic cell hybrid panel. heterologous primers designed for cat gene mapping were used in this study. forty-nine of these loci were localized into expected chromosome regions according to zoo-fish data, whereas four loci--alpl, cdc20, erf-2, and fc(mv)23617--were mapped out of expected conserved regions. pcr products amplified with primers correspondi ...200314557391
molecular survey of genetic diversity in the endangered european mink mustela lutreola.the european mink mustela lutreola is regarded as one of the most endangered mammals in the world. we chose to characterize microsatellite loci in order to investigate the pattern of decline of this species. we used primer pairs developed for a related species mustela vison to genotype individual of mustela lutreola. out of 19 primer pairs used 8 were useful for our purpose. the conservation of primer sequence point out the problem of neutrality of some microsatellite loci as this conservation c ...200314558449
interactions between melatonin and prolactin during gestation in mink (mustela vison).immature female mink, 8 weeks of age in july, were treated with implants releasing melatonin. mating, which induced ovulation, took place during the normal breeding season in the following march. circulating prolactin and progesterone concentrations did not undergo the expected gestational increases, and no embryos implanted. a similar absence of gestational changes in prolactin and progesterone values ensued in primiparous mink treated with the melatonin implant 2-3 days after the second of 2 m ...19902401973
[anthrax of the american mink]. 195214925518
cranial variation in british mustelids.nineteen measurements were made on 136 skulls belonging to seven mustelid species: meles meles (eurasian badger), mustela nivalis, (weasel), mustela erminea (stoat), mustela putorius (polecat), lutra lutra (otter), mustela furo (ferret), and mustela vison (american mink), and polecat-ferret hybrids. to investigate shape, size-related effects were eliminated by dividing all measurements by their geometric means. canonical variate analysis was used to reveal major interspecies distinctions. exclud ...200415052596
investigations into shaking mink syndrome: an encephalomyelitis of unknown cause in farmed mink (mustela vison) kits in scandinavia.an apparently novel neurological disease clinically characterized by shaking, tremors, seizures, staggering gait, and ataxia was first observed in farmed mink kits in denmark in 2000 and subsequently in sweden, denmark, and finland in 2001, and again in denmark in 2002. lymphoplasmacytic encephalomyelitis was found in the affected kits. the lesions were most severe in the brainstem and cerebellum and consisted of neuronal degeneration and necrosis, neuronophagia, focal and diffuse gliosis, periv ...200415305741
immunization with plasmid dna encoding the hemagglutinin and the nucleoprotein confers robust protection against a lethal canine distemper virus challenge.we have investigated the protective effect of immunization of a highly susceptible natural host of canine distemper virus (cdv) with dna plasmids encoding the viral nucleoprotein (n) and hemagglutinin (h). the combined intradermal and intramuscular routes of immunization elicited high virus-neutralizing serum antibody titres in mink (mustela vison). to mimic natural exposure, we also conducted challenge infection by horizontal transmission from infected contact animals. other groups received a l ...200415315843
endogenous zinc excretion in relation to various levels of dietary zinc intake in the mink (mustela vison).endogenous zinc excretion was studied in adult male mink fed experimental diets for 73 d, including a collection period from d 69 to 73. dietary zinc levels were 2.8, 26 or 121 mg/kg wet weight. in accordance with the results of a methodological study, also reported here, the animals had an intramuscular injection of 65zncl2 12 d before the start of the collection period. total fecal (endogenous + unabsorbed) zinc excretion for d 69-73 in the three groups was 2.3, 20.4 and 91.0 mg. the endogenou ...19902199634
short-term fasting induces intra-hepatic lipid accumulation and decreases intestinal mass without reduced brush-border enzyme activity in mink (mustela vison) small intestine.for many mammalian species short-term fasting is associated with intestinal atrophy and decreased digestive capacity. under natural conditions, strictly carnivorous animals often experience prey scarcity during winter, and they may therefore be particularly well adapted to short-term food deprivation. to examine how the carnivorous gastrointestinal tract is affected by fasting, small-intestinal structure, brush-border enzyme activities and hepatic structure and function were examined in fed mink ...200415503054
karyotypic conservatism in the suborder feliformia (order carnivora).multidirectional comparative chromosome painting was used to investigate the karyotypic relationships among representative species from three feliformia families of the order carnivora (viverridae, hyaenidae and felidae). complete sets of painting probes derived from flow-sorted chromosomes of the domestic dog, american mink, and human were hybridized onto metaphases of the spotted hyena (crocuta crocuta, 2n = 40) and masked palm civet (paguma larvata, 2n = 44). extensive chromosomal conservatio ...200515627756
phytoestrogens alter the reproductive organ development in the mink (mustela vison).the aim of the present study was to examine the reproductive effects of two perorally applied phytoestrogens, genistein (8 mg/kg/day) and beta-sitosterol (50 mg/kg/day), on the mink (mustela vison) at human dietary exposure levels. parental generations were exposed over 9 months to these phytoestrogens and their offspring were exposed via gestation and lactation. parents and their offspring were sampled 21 days after the birth of the kits. sex hormone levels, sperm quality, organ weights, and de ...200515629188
[the behavior of the x chromosomes in intra- and interspecific hybrid cells of murine teratocarcinoma pcc4azal].we have demonstrated that x chromosomes are reactivated in hybrids obtained by fusion of mouse pcc4azai teratocarcinoma cells (xo, 39hprt-) with splenocytes from mouse females heterozygous in hprt gene. these hybrids are capable of spontaneous differentiation. we also obtained similar interspecies hybrids of pcc4azai cells with bone marrow cells of the american mink. the majority of such hybrids remained undifferentiated, however, after long-term cultivation at high cell density they differentia ...19911857596
bacterial diskospondylitis associated with posterior paresis/paralysis in north american farmed mink (mustela vison).posterior paresis/paralysis in farmed mink is responsible for significant morbidity and mortality, with individual farms reporting the loss of as many as 700 animals each year. although this disease has been recognized by north american mink farmers for approximately 40 years, there are few published reports focusing on this entity. the objective of this study was to investigate the etiology and pathogenesis of the disease. complete necropsy examinations were done on 40 clinically affected mink, ...200515753465
[surveillance on severe acute respiratory syndrome associated coronavirus in animals at a live animal market of guangzhou in 2004].to study the prevalence of severe acute respiratory syndrome coronavirus (sars-cov) like virus in animals at a live animal market of guanzhou in 2004 before and after culling of wild animal action taken by the local authority, in order to predict the re-emerging of sars from animal originals in this region.200515921605
[comparative cytogenetic analysis of cells of mouse-mink inter-species hybridoma lines].the comparative cytogenetic analysis of the interspecific mouse-mink hybridoma cells revealed a segregation of the great number of the mink chromosomes, inter- and intraline variability according to the number of cells with the mink dna and its quantity in the cells. no characteristics of the mink chromosomal material distribution in the hybridoma cells which secreted the immunoglobulins of the american mink or lost its secretion were found. the great changes in the karyotype of the hybrid cells ...19911805468
efficacy of imidacloprid, imidacloprid/permethrin and phoxim for flea control in the mustelidae (ferrets, mink).farmed mink (mustela vison), a close relative of the domestic ferret (mustela putorius furo), naturally infested with the squirrel flea (ceratophyllus sciurorum) were included in a study to investigate three compounds for flea control. the test products were imidacloprid in a 10% (w/v) solution, an imidacloprid 10% (w/v)/permethrin 50% (w/v) solution, and phoxim; all three are well-known compounds for the control of different ectoparasites in a wide range of animals. two groups of mink received ...200516228265
b2-like repetitive sequence from the x chromosome of the american mink (mustela vison).in analysis of the repeats from the mink x chromosome (chr), we have identified a b2-like repetitive sequence of 195 base pairs (bp) flanked by short direct repeats of 14 bp. it contains regions homologous to the split intragenic rna polymerase iii promoter and a 3' a-rich region followed by an oligo(da) sequence. a feature of the repeat is the presence of a perfect polypyrimidine tract 22 bp in length absent from the known alu- and alu-like sequences. alignment of the mink b2-like sequence and ...19911797231
breaking an absolute species barrier: transgenic mice expressing the mink prp gene are susceptible to transmissible mink encephalopathy.transmissible mink encephalopathy (tme) is a rare disease of the north american mink, which has never been successfully transmitted to laboratory mice. we generated transgenic mice expressing the mink prion protein (prp) and inoculated them with tme or the mouse-adapted scrapie strain 79a. tme infected mink prp-transgenic mice on a murine prp knockout background. the absolute species barrier between the infectious agent of tme and mice was therefore broken. following tme and 79a infection of mic ...200516282497
cortisol increases the activities of intestinal apical membrane hydrolases and nutrient transporters before weaning in mink (mustela vison).glucocorticoids from endogenous and exogenous sources accelerate maturation of brush-border membrane (bbm) hydrolases in omnivorous laboratory rodents and pigs. less is known for carnivores, and whether the route of administration (oral or systemic) has an influence. the present study examined the influence of administering cortisol (hydrocortisone succinate, 5 mg/kg-day) to mink during postnatal week 4, just prior to weaning, on small intestine glucose and amino acid (aspartate, leucine, lysine ...200616344990
patterns and significance of bite wounds in eurasian otters (lutra lutra) in southern and south-west england.postmortem examinations were carried out on 379 otters found dead in southern and south-west england between 1988 and 2003. most (81 per cent) were road casualties, but many had open bite wounds and in some cases these had proved fatal. mortality was strongly seasonal and was positively correlated with night length. although numbers decreased in the summer months, the prevalence of bite wounds in adults was highest in late summer. the number of otters examined annually and the prevalence of bite ...200616443836
epidemiological investigations on trichinella infections in farmed fur animals of estonia.farming of fur animals represents an important income in estonia. even though trichinella worms does not induce a symptomatic disease in carnivores, the carcasses of skinned animals can increase the biomass of the parasite in the environment, if they are not properly destroyed. the aim of the present survey was to study the prevalence of trichinella worms in farmed fur animals of estonia. of 281 muscle samples from blue foxes (alopex lagopus), silver foxes (vulpes vulpes fulva), minks (mustela v ...200616564631
pancreatitis associated with hyperlipoproteinaemia type i in mink (mustela vison): earliest detectable changes occur in mitochondria of exocrine cells.pancreatic tissue from young mink homozygous for a mutation in the lipoprotein lipase gene was studied by light and electron microscopy, with the aim of describing the earliest detectable changes in a process which rapidly progresses into overt pancreatitis. the mutation leads to hyperlipoproteinaemia, corresponding to hyperlipoproteinaemia type i in man. assessment of relevant hepatic and pancreatic enzymes were included in the investigation. the earliest detectable changes consisted of widespr ...200616709420
alien mink predation induces prolonged declines in archipelago amphibians.amphibians are undergoing enigmatic global declines variously attributed to a complex web of anthropogenic forces. alien predators pose a fundamental threat to biodiversity generally that is predicted to be most acute in island ecosystems. while amphibian eggs and tadpoles are vulnerable to aquatic predators, the effect of predators on adult, reproducing frogs, which most influence amphibian population processes, is unknown. here, we report on the responses of amphibian populations in the outer ...200616720400
cyp2d-related metabolism in animals of the canoidea superfamily - species differences.cyp2d-related drug metabolism in liver microsomes from animals of the canoidea super family, i.e. mink (mustela vison), bears (ursus arctos), foxes (vulpes vulpes) and dogs, were investigated. propranolol, bunitrolol and imipramine, which are typically substrates of cyp2d subfamilies, were used in the experiment. all the animals of the canoidea superfamily that were tested lacked the ability to catalyse 7-hydroxylation of propranolol, which is one of the major metabolic pathways in rats. stereos ...200616755362
metabolism of dietary cetoleic acid (22:1n-11) in mink (mustela vison) and gray seals (halichoerus grypus) studied using radiolabeled fatty acids.cetoleic acid (22:1n-11) is a good indicator of diet in marine predators and has proven to be an important fatty acid (fa) when using adipose tissue fa composition to study diet in marine mammals and seabirds. feeding studies have shown that 22:1 isomers are predictably underrepresented in adipose tissue relative to diet, implying that metabolism within the predator strongly influences the relationship between the level of these fas in diet and adipose tissue. fully understanding such metabolic ...200616826508
mustela vison ace2 functions as a receptor for sars-coronavirus. 200617037586
[homology between the lpm system of allotypes in the american mink and the gp system of allotypes in the domestic pig].the 5 alpha-macroglobulin allotypes alpha m1, alpha m2, alpha m3, alpha m4 and alpha m5 were identified in pig. the alpha m1 allotype was reported as a marker of pig alpha-macroglobulin, the latter being homologous to alpha 2-macroglobulins in human and in mink. the allotypes alpha m2-alpha m5 were specified as markers of the second isotypical variant of pig alpha-macroglobulins, which was homologous to mink lpm macroglobulin (alpha 1m). as seen from data obtained by international comparative te ...19911714847
first report of cryptosporidium parvum 'ferret' genotype in american mink (mustela vison shreber 1777).a total of 51 faecal samples from wild and farmed mink were analysed by a direct immunofluorescence antibody test. cryptosporidium oocysts were identified in eight, apparently healthy, farmed american mink (mustela vison). the isolates were identified as cryptosporidium parvum 'ferret' genotype by pcr-rflp and sequencing analysis of a 341-base-pair fragment of the cryptosporidium oocyst wall protein (cowp) gene. this is the first report of cryptosporidium in american mink.200717111177
immunohistochemical detection of 3 viral infections in paraffin-embedded tissue from mink (mustela vison): a tissue-microarray-based study.immunohistochemical (ihc) assays were developed and tested for the detection of 3 viral infections in archived paraffin-embedded mink tissue. specimens had been obtained from mink with diagnoses of acute aleutian disease (ad), mink parvoviral enteritis (mve), or canine distemper (cd) made by means of routine diagnostic procedures. to improve the efficiency and reduce the costs of ihc analyses, tissue microarray (tma) technology was used. representative cores 2 mm in diameter from each tissue spe ...200717193876
investigation of mink mhc (mhcmuvi) class i molecules by isoelectric focusing (ief).mink (mustela vision) class i leucocyte antigens, here abbreviated mhcmuvi according to the proposal given by klein et al. (1990), were characterized by isoelectric focusing (ief), using triton x-114-extracted and neuraminidase-treated membrane proteins from spleen cells, followed by immunoblotting and development with a murine monoclonal antibody raised against denatured major histocompatibility complex (mhc) class i antigens. muvi class i antigens were investigated in a group of 97 danish mink ...19911681893
epidemiology, histopathology, and muscle distribution of trichinella t9 in feral raccoons (procyon lotor) and wildlife of japan.the prevalences of trichinella t9 in trapped raccoons (procyon lotor) and several other potential mammalian reservoirs in hokkaido, wakayama, and nagasaki prefectures were investigated. muscle samples were collected from 2003 to 2006 from 1,080 raccoons, 113 raccoon dogs including 2 species (nyctereutes procyonoides albus and n. p. viverrinus), 41 wild boars (sus scrofa leucomystax), 14 martens (martes melampus), 10 badgers (meles meles), 5 siberian weasels (martes sibirica coreana), 7 mink (mus ...200717310398
a test of mink microsatellite markers in the ferret: amplification and sequence comparisons.short tandem repeats are a source of highly polymorphic markers in mammalian genomes. genetic variation at these hypervariable loci is extensively used for linkage analysis and to identify individuals, and is very useful for interpopulation and interspecies studies. fifty-nine microsatellite markers from american mink were tested in the ferret, under the same conditions as for the mink. of the 59, 43 of them (73.5%) amplified a ferret sequence; 5 amplification products differed in size from the ...200617362355
mapping of the silver gene in mink and its association with the dilution gene in dog.in mink, recessive and dominant genes carry standard colors from generation to generation but breeding and cross breeding of naturally occurring mutations (color changes) has resulted in farmed animals bearing colors that do not exist in nature. the silver blue color type is one of the most used recessive mutations within mink fur farming being part of some of the popular color types which combine more recessive mutations. we report here the mapping of the 'silver' gene on mvi3 by means of the f ...200717431331
prevalence of cryptosporidium species in wildlife populations within a watershed landscape in southeastern new york state.a cross-sectional study was conducted to determine the prevalence of cryptosporidium in wildlife in the new york city (nyc) watershed in southeastern new york state. a total of 6227 fecal samples were collected and evaluated from 5892 mammals (38 species), 263 birds (14 species), 2 reptiles (2 species), 8 amphibians (4 species), and 62 fish (15 species). cryptosporidium was detected in 30 species. of the species found positive for cryptosporidium, 16 represented new records for this parasite-alo ...200717466459
isolation and cultivation of blastocyst-derived stem cell lines from american mink (mustela vison).ten embryonic stem (es) cell lines from mink blastocysts were isolated and characterized. all the lines had a normal diploid karyotype; of the ten lines studied, five had the xx and five had the xy constitution. testing of the pluripotency of the es-like cells demonstrated that 1) among four lines of genotype xx, and x was late-replicating in three; both xs were active in about one-third of cells of line mes8, and analysis of glucose-6-phosphate dehydrogenase revealed no dosage compensation for ...19921282024
first u.s. record of the hard tick ixodes (pholeoixodes) gregsoni lindquist, wu, and redner.ixodes (pholeoixodes) gregsoni lindquist, wu, and redner, a species of hard tick described in 1999 in canada, was recovered from a harvested fisher (martes pennanti erxleben) and a domestic cat (felis silvestris catus ragni and randi) in vermont in 2001 and from harvested mink (mustela vison schreber) in maine in 2003. these samples are the first records of this species within the united states. although knowledge of this tick's natural history and distribution are still preliminary, these recor ...200717626374
parasitic helminths of free-ranging mink (neovison vison mink) from southern florida.five free-ranging mink, neovison vison mink, from in or near the fakahatchee strand preserve state park, collier county, florida (26 degrees 00'n, 81 degrees 25'w), were examined for parasitic helminths. nine species of helminths were identified (2 trematodes, 5 nematodes, and 2 acanthocephalans). the most prevalent parasites were molineus patens (4 of 5 mink), mean intensity 173 (range, 12-342); strongyloides sp. (4 of 5), mean intensity 48 (range, 1-170); macracanthorhynchus ingens (immature) ...200717918381
[comparative mapping of mink (mustela vison) chromosome 8p: localization of three human bac clones].using fluorescent in situ hybridization (fish), three human bac clones, localized in the terminal region of human chromosome 17p (hsa17p13; 1.44--3.68 mp), were mapped to chromosome 8p of american mink (mvi8p). it was demonstrated that in mvi8p the region, homeologous to hsa17p13, was split into three fragments, which were detected within terminal, pericentric, and probably nucleolus-organizing regions. using human bac clones as heterologous markers for mapping of the gene sequences to the chrom ...200717958307
evaluation of reproductive safety of beta-sitosterol on the american mink (neovison vison).beta-sitosterol is a weakly estrogenic phytosterol used extensively in functional foods to lower elevated serum cholesterol concentrations due to its inhibitory action on intestinal cholesterol absorption. it caused previously decreased sex steroid concentrations in fish and lowered sperm counts in rats. in the american mink (neovison vison), litter size increased slightly due to dietary beta-sitosterol supplement. the aim of the present experiment was to conduct a dose-response study on the eff ...200818035394
geographic and host range of the nematode soboliphyme baturini across beringia.the nematode soboliphyme baturini petrov, 1930, was found to represent a single species with a relatively broad geographic range across beringia and northwestern north america on the basis of the assessment of molecular sequence data for adult and juvenile parasites. refuted are hypotheses suggesting that several cryptic species could be partitioned either among an array of mustelid definitive hosts or across the vast region that links north america and eurasia. host specificity for this species ...200718163341
from aquatic to terrestrial food webs: decrease of the docosahexaenoic acid/linoleic acid ratio.fatty acid composition of the adipose tissue of six carnivorous mammalian species (european otter lutra lutra, american mink mustela vison, european mink mustela lutreola, european polecat mustela putorius, stone marten martes foina and european wild cat felis silvestris) was studied. these species forage to differing degrees in aquatic and terrestrial food webs. fatty acid analysis revealed significant differences in polyunsaturated fatty acid composition between species. more specifically, our ...200818335265
a species barrier limits transmission of chronic wasting disease to mink (mustela vison).transmissible mink encephalopathy (tme) occurs as sporadic outbreaks associated with ingestion of feed presumably contaminated with some type of prion disease. mink lack a species barrier to primary oral challenge with bovine spongiform encephalopathy, whereas they have a barrier to such challenge with scrapie. we investigated whether mink have a species barrier to chronic wasting disease (cwd) by performing primary intracerebral (ic) and primary oral challenge with cwd-positive elk brain. prima ...200818343853
molecular characterization of a new genotype of cryptosporidium from american minks (mustela vison) in china.a total of 469 fecal samples were collected from american minks (mustela vison) on a farm in hebei province in china and examined for cryptosporidium by sheather's sugar flotation technique and 8 cryptosporidim isolates were obtained. the partial 18s rrna, 70kda heat shock protein (hsp70), cryptosporidium oocyst wall protein (cowp) and actin genes of six isolates were sequenced. sequence data were analyzed together with known cryptosporidium spp. and genotypes. results of this multi-locus geneti ...200818434024
intrageneric diversity of the cytochrome b gene and phylogeny of eurasian species of the genus mustela (mustelidae, carnivora).to illuminate molecular phylogenetic relationships among eurasian species of the genus mustela (mustelidae, carnivora), we determined nucleotide sequences of the complete mitochondrial cytochrome b gene region (1,140 base pairs). molecular phylogenetic trees, constructed using the neighbor-joining and the maximum likelihood methods, showed the common topology of species relationships to each other. the american mink m. vison first branched off and was positioned very remotely from the other spec ...200018517304
[animal corynosomosis is a potential human helminthiasis in the republic of belarus].in the republic of belarus, one representative of the genus corynosoma - c. strumosum (rudolphi, 1802) that is a causative agent of corynosomosis and that is of medical value is parasitic on animals. in belarus, this proboscis worm has been encountered only in european and american minks. the author of the paper found this helminth in 2 of the 50 examined american minks in byelorussian polesye in 1980-2001. in this region, there were no c. strumosum larvae in fishes (1394 fishes of 21 species we ...200818557363
molecular and morphometric study of metacercariae and adults of pseudamphistomum truncatum (opisthorchiidae) from roach (rutilus rutilus) and wild american mink (mustela vison).the presence of metacercariae and adults of the trematode pseudamphistomum truncatum in roach and mink, respectively, was recorded in lake fure north of copenhagen, denmark. this zoonotic digenean opisthorchiid represents a threat to humans due to its ability to infect the biliary system following ingestion of inadequately processed infected fish. therefore precise species identification of infective metacercariae in fish used for human consumption is essential. due to the relatively limited inf ...200818571328
anatomy of the retina of the mink (mustela vison).the retina of the normal pigmented mink has been studied by light and electron microscopy. this retina resembles the typical vertebrate retinia in its patterns of lamination and synaptic interconnectivity. rod and cone outer segments and receptor spherule and pedicle endings are found. at least two different types of horizontal cell processes are seen with the electron microscope, suggestive of rabbit a and b types. ribbon and conventional synapses are found in both plexiform layers; conventiona ...1977856884
aleutian disease serology, protein electrophoresis, and pathology of the european mink (mustela lutreola) from navarra, spain.the european mink, mustela lutreola, has suffered a dramatic decline in europe during the 20th century and is one of the most endangered carnivores in the world. the subpopulation of european mink from navarra, spain, estimated to number approximately 420, represents approximately two thirds of the total number of mink in spain. aleutian disease virus (adv) is a parvovirus with a high degree of variability that can infect a broad range of mustelid hosts. the pathogenesis of this virus in small c ...200818816991
genetic identification of mammalian carnivore species in the kushiro wetland, eastern hokkaido, japan, by analysis of fecal dna.to identify mammalian carnivore species distributed in the kushiro wetland, eastern hokkaido, japan, we developed molecular-genetic methods for identification of the species from fecal samples collected from the field. species-specific primers and pcr programs were established for five native and six alien species of carnivores: martes zibellina, mustela nivalis, mustela erminea, vulpes vulpes, and nyctereutes procyonoides as native species, and neovison vison, martes melampus, mustela itatsi, c ...200818828658
serologic survey for selected viral pathogens in free-ranging endangered european mink (mustela lutreola) and other mustelids from south-western france.to investigate the possible role of selected pathogens in the decline of endangered european mink (mustela lutreola) populations and the potential for these pathogens to affect mink survival, a serologic survey was conducted using serum samples collected from march 1996 to march 2003 in eight departments of south-western france. in total, 481 free-ranging individuals of five mustelid species (including the european mink) were tested. sympatric mustelids can serve as sentinels to determine the pr ...200818957635
sequencing and characterization of mixed function monooxygenase genes cyp1a1 and cyp1a2 of mink (mustela vison) to facilitate study of dioxin-like compounds.as part of an ongoing effort to understand aryl hydrocarbon receptor (ahr) mediated toxicity in mink, cdnas encoding for cyp1a1 and the cyp1a2 mixed function monooxygenases were cloned and characterized. in addition, the effects of selected dibenzofurans on the expression of these genes and the presence of their respective proteins (p4501a) were investigated, and then correlated with the catalytic activities of these proteins as measured by ethoxyresorufin o-deethylase (erod) and methoxyresorufi ...200919041884
metabolizable energy requirement for maintenance and body composition of growing farm-raised male pastel mink (mustela vison).the requirement of metabolizable energy (me) for maintenance was studied in 31 male pastel farm-raised mink. the procedure used was a body balance regression technique that included an initial baseline group, a group allowed feed ad libitum, and a group allowed feed at the level of 65% of average intake of the ad libitum animals. the requirement for me was 147.8 +/- 6.06 kcal/wtkg 0.734/day. this value falls within the range of estimates of maintenance requirements noted for younger animals of o ...1978722343
development and use of real-time reverse transcription-polymerase chain reaction assay to quantify cytochrome p4501a1 expression in american mink.the distribution of natural populations of american mink is restricted to locales that are in proximity to aquatic ecosystems. because of the lipophilicity and persistence of polychlorinated biphenyls (pcbs) and reliance of mink on aquatic-based diets, mink at contaminated locales often bioacccumulate high levels of pcbs. in addition, in controlled laboratory studies, mink are highly sensitive at reproductive and developmental end points to the toxic effects of environmental pcb mixtures. it is ...200919277445
molecular characterization of the himalayan mink.a rare color variant of the american mink (neovison vison), discovered on a ranch in nova scotia and referred to as the "marbled" variety, carries a distinctive pigment distribution pattern resembling that found in some other species, e.g., the siamese cat and the himalayan mouse. we tested the hypothesis that the color pattern in question-light-colored body with dark-colored points (ears, face, tail, and feet)-is due to a mutation in the melanin-producing enzyme tyrosinase (tyr) that results in ...200919308642
high plasma cholesterol in mink (mustela vison) without atherosclerosis.mink fed a commercial ration moderately high in cholesterol or fed a cholesterol-free semipurified diet have plasma cholesterol-free semipurified diet have plasma cholesterol concentrations similar to that found in human beings living in industrialized countries. in contrast with human beings, 80% of the plasma cholesterol in mink is carried in the high density lipoprotein fraction. aortas and coronary arteries from animals up to 8 yr old were found to be free of fatty streaks and atheroscleroti ...1977189781
an extended anchored linkage map and virtual mapping for the american mink genome based on homology to human and dog.in this report we present an extended linkage map of the american mink (neovison vison) consisting of 157 microsatellite markers and comprising at least one linkage group for each of the autosomes. each linkage group has been assigned to a chromosome and oriented by fluorescence in situ hybridization (fish) and/or by means of human/dog/mink comparative homology. the average interval between markers is 8.5 cm and the linkage groups collectively span 1340 cm. in addition, 217 and 275 mink microsat ...200919520153
the impact of native competitors on an alien invasive: temporal niche shifts to avoid interspecific aggression?the american mink, neovison vison, is an established, alien invasive species in the united kingdom that originally colonized the country at a time when two native mustelids (otters, lutra lutra, and polecats, mustela putorius) were largely absent. both of these species are now recovering their populations nationally. we compared the relative abundance and the behavior of mink in the 1990s and in the 2000s in an area of southern england where both otters and polecats were absent in the 1990s but ...200919537542
chromosomal mapping of canine-derived bac clones to the red fox and american mink genomes.high-quality sequencing of the dog (canis lupus familiaris) genome has enabled enormous progress in genetic mapping of canine phenotypic variation. the red fox (vulpes vulpes), another canid species, also exhibits a wide range of variation in coat color, morphology, and behavior. although the fox genome has not yet been sequenced, canine genomic resources have been used to construct a meiotic linkage map of the red fox genome and begin genetic mapping in foxes. however, a more detailed gene-spec ...200919546120
surveillance for transmissible spongiform encephalopathy in scavengers of white-tailed deer carcasses in the chronic wasting disease area of wisconsin.chronic wasting disease (cwd), a class of neurodegenerative transmissible spongiform encephalopathies (tse) occurring in cervids, is found in a number of states and provinces across north america. misfolded prions, the infectious agents of cwd, are deposited in the environment via carcass remains and excreta, and pose a threat of cross-species transmission. in this study tissues were tested from 812 representative mammalian scavengers, collected in the cwd-affected area of wisconsin, for tse inf ...200919697235
do rabbits eat voles? apparent competition, habitat heterogeneity and large-scale coexistence under mink predation.habitat heterogeneity is predicted to profoundly influence the dynamics of indirect interspecific interactions; however, despite potentially significant consequences for multi-species persistence, this remains almost completely unexplored in large-scale natural landscapes. moreover, how spatial habitat heterogeneity affects the persistence of interacting invasive and native species is also poorly understood. here we show how the persistence of a native prey (water vole, arvicola terrestris) is d ...200919708968
canine distemper epizootic in everglades mink.four free-ranging mink, neovison vison, collected between june and september 2004 in the fakahatchee strand preserve state park (fspsp, florida, usa), were examined for canine distemper virus (cdv) infection. microscopic lesions and viral inclusions consistent with cdv infection were observed in three mink. virus isolation and reverse transcription-polymerase chain reaction performed on all mink were positive for cdv. anecdotal records of mink observations in fspsp suggest a postepizootic declin ...200919901388
serogroups and antimicrobial susceptibility among escherichia coli isolated from farmed mink (mustela vison schreiber) in denmark.escherichia coli is commonly found in outbreaks of diarrhoea in mink during the production season although its role as a primary causal organism remains unclear. the present study was undertaken to determine the serogroups and antimicrobial susceptibility of e. coli isolates from healthy and diarrhoeic mink. rectal swabs were taken from healthy and diseased animals, on six different farms, once at the onset of disease and again approximately 2 weeks later. the swabs were subjected to bacteriolog ...200111230936
effect of dietary glycine and benzoate level on benzoate metabolism in mink (mustela vision), blue fox (alopex lagopus), and raccoon dog (nyctereutes procyonoides).three 2 x 4 factorial experiments were carried out from august to september with 30 juvenile male mink, 24 raccoon dogs, and 24 blue foxes to investigate the effect of dietary glycine supply (low or high) on the efficiency of these species to excrete hippuric acid with incremental benzoate intake (0, 1, 2, or 4 mmol/kg bw). for mink, two additional treatments with 1 or 2 mmol/kg bw of ethyl benzoate were included. a basal low-glycine diet was formulated to meet the minimum protein requirements o ...200010784188
a survey of aleutian mink disease virus infection of feral american mink in nova scotia.spleen samples from 14 mink that were trapped in 4 counties of nova scotia were tested for the presence of the aleutian mink disease virus (amdv) by polymerase chain reaction. viral dna was not detected in samples from kings county (n = 2), but was detected in all the mink sampled from colchester (n = 2) and halifax (n = 6) counties, and 3 of 4 mink from yarmouth county. the high level of amdv-infected mink in colchester and halifax counties may pose a serious threat to the captive mink and wild ...201020357945
anthrax in mink (mustela vison). 193920475478
genetic analyses of fancy rat-derived mutations.to collect rat mutations and increase the value of the rat model system, we introduced fancy-derived mutations to the laboratory and carried out genetic analyses. six fancy rats were shipped from a fancy rat colony in the usa and used as founders. after initial crosses with a laboratory strain, tm/kyo or pvg/seac, inbreeding started and 6 partially inbred lines, including 2 sublines, were produced as kyoto fancy rat stock (kfrs) strains. during inbreeding, we isolated 9 mutations: 5 coat colors, ...201020484848
the response of water voles, arvicola terrestris, to the odours of predators.we investigated the response of water voles to the odours of predators in outdoor enclosures. water voles were given access to two food cages, one containing the odour of a predator and the other containing no odour, and were videotaped for 22 h. sheep odour was also used as a control for novel odour. the predators were american mink, mustela vison, and brown rat, rattus norvegicus. there was no difference in the voles' response to sheep odour and no odour. the voles entered the treatment cages ...199910328797
molecular evolution of adiponectin in carnivora and its mrna expression in relation to hepatic lipidosis.adiponectin is a novel adipocyte-derived hormone with low circulating concentrations and/or mrna expression in obesity and non-alcoholic fatty liver disease (nafld). the adiponectin mrna of several carnivora species was sequenced to enable further gene expression studies in this clade with potential experimental species to examine the connections of hypoadiponectinemia to hepatic lipidosis. in addition, adiponectin mrna expression was studied in the retroperitoneal fat of the american mink (neov ...201020553720
toxic effects to mink of moniliformin extracted from fusarium fujikuroi culture material.acute and subacute effects of i.p. exposure to moniliformin in mink (mustela vison) were investigated. moniliformin was extracted from fusarium fujikuroi culture material containing 9,174 ppm moniliformin. an acute ld50 between 2.2 and 2.8 mg moniliformin/kg bw was determined for 9-mo-old female mink. subacute exposure to 1.5 to 3.2 mg total moniliformin/kg bw resulted in dilated (right side) hearts rounded in appearance. statistical differences observed in serum chloride and albumin, amylase ac ...19999949474
biliary parasite pseudamphistomum truncatum (opistorchiidae) in american mink (mustela vison) and eurasian otter (lutra lutra) in ireland.native eurasian otter (lutra lutra) and introduced american mink (mustela vison) carcasses collected throughout ireland were screened for biliary parasites. secondary intermediate hosts, cyprinid fish, were also examined for opistorchiid metacercariae. twenty-nine mink and 24 otter gall bladders were screened for biliary parasites. a single mink and three otters were found to be infected with the digenetic trematode pseudamphistomum truncatum. eighty-nine percent of roach (rutilus rutilus) from ...201020582437
full genome comparison and characterization of avian h10 viruses with different pathogenicity in mink (mustela vison) reveals genetic and functional differences in the non-structural gene.the unique property of some avian h10 viruses, particularly the ability to cause severe disease in mink without prior adaptation, enabled our study. coupled with previous experimental data and genetic characterization here we tried to investigate the possible influence of different genes on the virulence of these h10 avian influenza viruses in mink.201020591155
the accidental release of exotic species from breeding colonies and zoological collections.exotic species have often been introduced into a new country in zoological or botanical gardens or on game and fur farms. when accidentally or deliberately released, these alien species can become invasive and have negative impacts on native plant and animal communities and human activities. this article focuses on a selection of such invasive species: principally the american mink (neovison vison), but also the coypu (myocastor coypus), muskrat (ondatra zibethicus), raccoon dog (nyctereutes pro ...201020617652
multigenerational study of the effects of consumption of pcb-contaminated carp from saginaw bay, lake huron, on mink. 1. effects on mink reproduction, kit growth and survival, and selected biological parameters.this study was conducted to determine the multigenerational effects of consumption of pcb-contaminated carp (cyprinus carpio) from saginaw bay (lake huron) on mink (mustela vison) reproduction and health and to examine selected biomarkers as potential indicators of polyhalogenated hydrocarbon toxicity in mink. the mink were fed diets formulated to provide 0 (control), 0.25, 0.5, or 1.0 ppm polychlorinated biphenyls (pcbs) through substitution of saginaw bay carp for ocean fish in the diets. to d ...19989650571
angiostrongylus species in wild carnivores in the iberian peninsula.a survey of angiostrongylus parasites was carried out between 2003 and 2006 in wild carnivore species in the basque country (northern spain). parasitological examination consisted in the dissection of heart and lungs for the extraction of adult worms. nematodes were identified using morphometrical features and also pcr amplification and sequencing analysis. the animal species included in this study were eurasian badger (meles meles), weasel (mustela nivalis), beech marten (martes foina), pine ma ...201020728995
two avian h10 influenza a virus strains with different pathogenicity for mink (mustela vison).we compared two strains of avian influenza a viruses of subtype h10 by exposing mink to aerosols of a/mink/sweden/3,900/84 (h10n4) naturally pathogenic for mink, or a/chicken/germany/n/49, (h10n7). lesions in the respiratory tract during the first week after infection were studied and described. both virus strains caused inflammatory reactions in the lungs and antibody production in exposed mink but only mink/84 virus was reisolated. the lesions caused by mink/84 virus were more severe with high ...19989638139
dietary fumonisins disrupt sphingolipid metabolism in mink and increase the free sphinganine to sphingosine ratio in urine but not in hair.this study was conducted to investigate the effects of dietary fusarium moniliforme culture material (m-1325) containing known concentrations of fumonisins b1, b2 and b3 on sphingolipids in urine and hair of mink (mustela vison) for use as potential, non-invasive biomarkers of exposure to fumonisins in this species. feeding mink diets containing 86, 22, and 7 ppm or 200, 42, and 12 ppm of fumonisins b1, b2 and b3, respectively, yielded marked increases in urinary free sphinganine (sa) and free s ...19979397500
the role of glucocorticoids in the growth of the digestive tract in mink (mustela vison).the effect of glucocorticoids on the growth of digestive organs was investigated in the postnatal period of mink. a total of 110 mink kits from 20 litters were either not injected or injected intramuscularly for seven days with saline, adrenocorticotropic hormone (acth, 50 micrograms/kg/day) or hydrocortisone-acetate (synthetic glucocorticoid, 50 mg/kg/day). the kits were killed at 2-10 weeks of age. plasma cortisol levels did not change significantly with age in the control animals. in the acth ...19968858837
[comparative substrate-inhibitor analysis of liver monoamine oxidases of minks].comparative substrate-inhibitor analysis of catalytic properties of liver monoamine oxidases (mao) was performed in the mature males of the american mink mustela vison and the european mink mustela lutreola. the action on the mao activity was studied of alkaloids of the benzo[c]phenanthridine group: sanguinarine and chelidonine, diisoquinoline alkaloid berberine, medication agents ukrain and sanguirythrin as well as derivatives of 2-propylamine: deprenyl and clorgylin. the latter turned out to b ...201021061647
diversity and stability of aleutian mink disease virus during bottleneck transitions resulting from eradication in domestic mink in denmark.aleutian mink disease (plasmacytosis) virus (amdv) in domestic mink (neovison vison) has been subject to eradication in denmark since 1976. in 2001, approximately 5% of danish mink farms were still infected and all were located in the northern part of the peninsula of jutland. in the present study a total of 274 danish isolates of amdv collected during the two seasons of 2004 and 2005 were characterized by partial sequencing of the coding region of the non-structural (ns) proteins. older amdv is ...201021112164
[evaluation of the immune response after vaccination against distemper at a mink (mustela vison) farm in argentina].distemper virus causes a disease affecting minks with respiratory, gastrointestinal, neurological and skin symptoms and showing high morbidity and mortality, mainly among puppies. it is controlled through immunization, using vaccines that are supplied for mink use. the aim of this work was to determine the seroneutralization titer against the distemper virus at a mink farm in argentina. the antibody kinetics obtained after vaccination in 27 adult animals, as well as the duration of colostrum-tra ...201021186672
differences in the ability to suppress interferon β production between allele a and allele b ns1 proteins from h10 influenza a viruses.in our previous study concerning the genetic relationship among h10 avian influenza viruses with different pathogenicity in mink (mustela vison), we found that these differences were related to amino acid variations in the ns1 protein. in this study, we extend our previous work to further investigate the effect of the ns1 from different gene pools on type i ifn promoter activity, the production of ifn-β, as well as the expression of the ifn-β mrna in response to poly i:c.201021194454
forecasting risk of tick-borne encephalitis (tbe): using data from wildlife and climate to predict next year's number of human victims.over the past quarter century, the incidence of tick-borne encephalitis (tbe) has increased in most european nations. however, the number of humans stricken by the disease varies from year to year. a method for predicting major increases and decreases is needed.201121254953
molecular characterization of a new species in the genus alphacoronavirus associated with mink epizootic catarrhal gastroenteritis.a coronavirus (cov) previously shown to be associated with catarrhal gastroenteritis in mink (mustela vison) was identified by electron microscopy in mink faeces from two fur farms in wisconsin and minnesota in 1998. a pan-coronavirus and a genus-specific rt-pcr assay were used initially to demonstrate that the newly discovered mink covs (mcovs) were members of the genus alphacoronavirus. subsequently, using a random rt-pcr approach, full-genomic sequences were generated that further confirmed t ...201121346029
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