| inhibition of α-glucosidase by new prenylated flavonoids from euphorbia hirta l. herb. | euphorbia hirta l. (euphorbiaceae) is a pantropical medicinal rhizomatous herb, traditionally used in the treatment of diabetes, respiratory and gastro-intestinal disorders. | 2015 | 26477374 |
| evaluation of the cytotoxicity, cell-cycle arrest, and apoptotic induction by euphorbia hirta in mcf-7 breast cancer cells. | euphorbia hirta l. (euphorbiaceae) has been used as a folk remedy in southeast asia for the treatment of various ailments. | 2016 | 26154521 |
| protective effect of euphorbia hirta and its components against snake venom induced lethality. | despite the use of snake anti-venom therapy, herbal medicine is still in practice to treat snakebites. euphorbia hirta is traditionally used as antidote for snakebites and also for numerous other ailments. however, the scientific evidence for its anti-snake venom property is still lacking. | 2015 | 25727964 |
| in vitro anti-inflammatory activity of fractionated euphorbia hirta aqueous extract on rabbit synovial fibroblasts. | euphorbia hirta has been reported to possess anti-inflammatory activity. this study was carried out to determine the prostaglandin e 2 (pge 2 ) inhibition activity of the fractions of the e. hirta aqueous extract on rabbit synovial fibroblast cells (hig-82). | 2016 | 25673170 |
| minerals salt composition and secondary metabolites of euphorbia hirta linn., an antihyperglycemic plant. | phytochemical study and research on acute toxicity were performed on the aerial parts (leaves and stems) of euphorbia hirta linn. the phytochemical screening and chromatography revealed the presence of saponin, sterol, terpene, alkaloids, polyphenols, tannins and flavonoids and especially mucilage. the evaluation of total polyphenols and total flavonoids gave 120.97 ± 7.07 gallic acid equivalents (gae) mg/g (mg of gae/g of extract) of dry extract and 41.4 ± 0.5 mg quercetin equivalent per gram ( ... | 2017 | 25598628 |
| reduction of adhesion molecule production and alteration of enos and endothelin-1 mrna expression in endothelium by euphorbia hirta l. through its beneficial β-amyrin molecule. | the inflammatory reaction in large blood vessels involves up-regulation of vascular adhesion molecules such as endothelial cell selectin (e-selectin), soluble vascular cell adhesion molecule (svcam)-1, and soluble intercellular adhesion molecule (sicam)-1. these vascular dysfunctions are associated with the development of atherosclerosis. β-amyrin, an active component of euphorbia hirta l., has potent anti-inflammatory effects. so far, its preventive effects against the expression of inflammator ... | 2014 | 25045892 |
| prophylactic and curative anti-ulcerative colitis activity and the possible mechanisms of action of some desert plants. | the aim of the present study was to evaluate both prophylactic and curative anti-ulcerative colitis activity and the possible mechanism of action of seven desert plant extracts. seven desert plants from different families; conyza dioscoridis (l.) desf. (asteraceae), euphorbia hirta l. (euphorpiaceae), origanum syriacum l. and salvia lanigera l. (lamiaceae), sisymbrium irio l., solanum nigrum linn. (solanaceae) and solenostemma arghel (del.) hayne. (asclepiadaceae) were separately evaluated at th ... | 2015 | 24811429 |
| anti-inflammatory effect of euphorbia hirta in an adjuvant-induced arthritic murine model. | despite extensive research into inflammatory diseases to date, no drugs with favourable safety profiles are available for treatment. euphorbia hirta (e. hirta) is a tree that is locally used as a traditional medicine in africa and australia to treat numerous diseases such as hypertension, antipyretic and anti-inflammatory activities. the aim of the present study was to determine the potential anti-arthritic effects of e. hirta in mouse models of adjuvant induced arthritis (aia). we treated balb/ ... | 2014 | 24393059 |
| acute and subchronic toxicity study of euphorbia hirta l. methanol extract in rats. | despite euphorbia hirta l. ethnomedicinal benefits, very few studies have described the potential toxicity. the aim of the present study was to evaluate the in vivo toxicity of methanolic extracts of e. hirta. the acute and subchronic oral toxicity of e. hirta was evaluated in sprague dawley rats. the extract at a single dose of 5,000 mg/kg did not produce treatment related signs of toxicity or mortality in any of the animals tested during the 14-day observation period. therefore, the ld 50 of t ... | 2013 | 24386634 |
| the effects of euphorbia hirta on the ultrastructure of the murine liver, kidney and aorta. | euphorbia hirta is widely used in traditional remedies and has been used cross-culturally for generations against maladies such as asthma, skin ailments and hypertension. previous studies have demonstrated that euphorbia hirta has antibacterial activity, and have also indicated certain antimolluscidal, antimalarial and anti-inflammatory properties, the latter of which have been suggested to be more pronounced than those of the rheumatological drug, etanercept. to date, no studies have identified ... | 2013 | 24223653 |
| cytotoxicity and genotoxicity assessment of euphorbia hirta in mcf-7 cell line model using comet assay. | to evaluate the cytotoxicity and genotoxicity activity of euphorbia hirta (e. hirta) in mcf-7 cell line model using comet assay. | 2013 | 23998008 |
| green synthesis, characterization and antimicrobial activity of au nps using euphorbia hirta l. leaf extract. | the activity of a nano sized particle is said to be greater when compared to that of its parent materials combined. thus, an attempt was made to produce gold nanostructures having unusual physicochemical properties. in this study, eco-friendly, non-toxic gold nanoparticles (au nps) were biologically synthesized using the leaf extract of euphorbia hirta l. the synthesis of au nps was confirmed by a change in extract color from pale yellow to purple and surface plasmon resonance spectra obtained i ... | 2013 | 23528605 |
| tnf-α inhibitory effect of euphorbia hirta in rats. | euphorbia hirta l. (euphorbiaceae) (e. hirta) is a tree locally used as a traditional medicine in africa and australia to treat numerous diseases such as hypertension, respiratory ailments, tumors, and wounds, and it has reported antiallergic, antipyretic, anti-inflammatory activities, etc. | 2013 | 23336701 |
| modulation of th1 cytokines and inflammatory mediators by euphorbia hirta in animal model of adjuvant-induced arthritis. | euphorbia hirta l. (euphorbiaceae) (e. hirta) is a tree locally used as a traditional medicine in africa and australia to treat numerous diseases such as hypertension, respiratory ailments, tumors, antipyretic, anti-inflammatory activities. in the present study, we investigated the anti-arthritic activity of fresh leaves of e. hirta ethanol extract that was found to inhibit the production of inflammatory mediators and cytokines of adjuvant arthritis in rats. adjuvant arthritis was induced in rat ... | 2013 | 23229350 |
| acute toxicity impacts of euphorbia hirta l extract on behavior, organs body weight index and histopathology of organs of the mice and artemia salina. | the methanol extract of euphorbia hirta l (euphorbiaceae), which is used in traditional medicines, was tested for in vivo toxicity. | 2012 | 22923956 |