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diagnostic flexible bronchoscopy in human immunodeficiency virus (hiv)-positive children.twelve children with laboratory evidence of human immunodeficiency virus (hiv) infection underwent diagnostic flexible bronchoscopy with washings or bronchoalveolar lavage at bellevue hospital center from october 1987 to april 1989. the patients included 7 boys and 5 girls ranging from age 3.5 months to 10 years 5 months. indications for bronchoscopy included respiratory distress with or without focal changes on chest radiograph in 11 patients, and persistent but asymptomatic right middle lobe c ...19892625388
[pulmonary abscesses in material from tuberculosis and lung disease clinics of the academy of medicine in gdansk].47 patients with pulmonary abscesses were analysed. the type of bacteria cultured from the sputum, type of chemotherapy and clinical outcome were assessed. most of the patients (34) were already treated prior to admission to the department. most often with doxycycline and gentamycin. the following organisms were cultured: streptococcus viridans, escherichia coli, staphylococcus aureus and klebsiella pneumoniae. antibiotic therapy was always instituted according to the antibiogram. most often ami ...19902216912
bacterial endocarditis in children: clinical and laboratory findings, and the role of echocardiography in its diagnosis and management.we report clinical and laboratory findings of 15 children with bacterial endocarditis, admitted to the department of child health, university of indonesia/cipto mangunkusumo hospital from february, 1987 to june, 1989. there were 8 boys and 7 girls with bacterial endocarditis, ranging in age from 10 weeks to 16 years. the diagnosis was suspected because of prolonged fever, with or without other manifestations, i.e. congestive heart failure, refractory anemia, or paroxysmal atrial tachycardia. the ...19892631025
a clinical evaluation of sulbactam/ampicillin in the treatment of pediatric infections.we have treated 42 episodes of pediatric infections with sulbactam/ampicillin since 1987. included were 9 cellulitis, 9 urinary tract infections, 5 cervical lymphadenitis, 4 meningitis, 2 thoracic empyema, 2 osteomyelitis, 2 sepsis, 1 furuncle, 1 perianal abscess, 1 dental abscess, 1 peritonsillitis, 1 salmonellosis, 1 shigellosis, 1 peritonitis, 1 suppurative thyroiditis, 1 infective endocarditis. responsible pathogens were escherichia coli in 8, staphylococcus aureus in 6, hemophilus influenza ...19892637593
[prosthetic valve endocarditis].from january/1983 to march/1988, 28 patients were submitted to valve replacements for prosthetic valve endocarditis in 1,512 valve replacements. seventeen patients were male, their mean age was 36.7 +/- 12.9 years old, and eight cases were operated under emergency condition. the blood cultures were positive in 14 (50%), the agent most commonly found being streptococcus viridans in 5 cases. hospital mortality was 28.5%. the causes of death were septicemia in 4 cases, low output syndrome in 2 case ...19902232391
[clinical analysis of 53 cases of septicemia caused by streptococcus viridans in children].the clinical analysis has been performed in 53 cases of sepsis induced by streptococcus viridans. among children with diagnosis of sepsis majority of cases in group of older infant and children up to 2 year age was due to above infection. the s. viridans strain isolated form the blood were in 90% percentage resistant to cloxacillin , the resistance to penicillin, ampicillin and gentamicin was equal to 70%, 50% and 34% respectively. the main symptoms of the s. viridans sepsis was most frequently ...19902236628
[waterhouse-friderichsen syndrome in adults].only a minority of published cases of waterhouse-friderichsen-syndrome occurred in adults (harms et al., 1973). at the autopsy of a 23 years old woman there were found sugillations of the eyelid, of the peri- and epicard, of the serosa of the small intestine and of the lung. in the region of the adrenal gland a brownish-red mass was detectable. histologically an adrenal apoplexy with necrosis and in liver, spleen and lung a lot of neutrophils were seen. streptococcus viridans was pointed out in ...19902241795
suture-wick endophthalmitis with sutured posterior chamber intraocular lenses.a patient had a corneal transplant with removal of an anterior chamber lens. as part of the procedure, an exchange posterior chamber lens was inserted and sutured transsclerally into the ciliary sulcus with two subconjunctival 10-0 polypropylene (prolene) sutures. one month later the patient experienced a sudden decrease in vision and severe eye pain. streptococcus viridans was cultured from the vitreous tap and the eye eventually was lost from this endophthalmitis. the infecting organism appear ...19902258814
septic arthritis due to streptococcus viridans. 19902261714
primary streptococcus viridans pneumonia.we describe three cases of acute uncomplicated bacterial pneumonia due to viridans streptococci in previously healthy adults, which were indistinguishable from those caused by other well-known respiratory pathogens. on arrival, all of these patients were treated with iv aqueous penicillin based on gram stain of sputum which showed predominant gram-positive cocci in pairs and chains. these specimens of sputum grew normal oral flora in the three cases. the diagnosis was confirmed by positive blood ...19892791680
bacteriology of unheated expressed breast milk stored at room temperature.thirty samples of unheated expressed breast milk (ebm) from thirty lactating mothers, stored at room temperature (rt) and in the refrigerator (at +4 degrees c), were examined for the degree of bacterial contamination at two hourly intervals upto eight hours. all the ebm samples contained bacteria, mostly of normal skin flora; staphylococcus albus 76.7%; streptococcus viridans 40%. potential pathogens were isolated in small numbers: escherichia coli 26%, streptococcus faecalis 13.6% and staphyloc ...19892791942
infectious crystalline keratopathy associated with topical anesthetic abuse.two patients with infectious crystalline keratopathy associated with topical anesthetic abuse are described. no previously reported predisposing factors existed, including topical corticosteroid use during active herpes simplex or acanthamoeba keratitis, or following penetrating keratoplasty. cultures from corneal biopsies of both patients grew streptococcus viridans. both infections resulted in corneal scarring with vascularization. ultimately, corneal transplantation was performed in one case.19902297999
[streptococcus viridans and respiratory failure in acute leukemia].through the last 18 months, five of our patients with acute leukaemia have developed septicaemia caused by streptococcus viridans, followed by acute respiratory failure. two patients had to be placed in a respirator. in patients with acute leukaemia treated with cytostatic drugs, close clinical observation, including repeated blood gas analysis, is very important if they develop septicaemia caused by streptococcus viridans. early administration of high doses of corticosteroids seems to be import ...19902300957
infectious endocarditis in children.with the object of analyzing current characteristics of infectious endocarditis (ie) in children, we carried out a retrospective study of 23 cases of ie in children under 15 years of age seen at the hospital ramón y cajal in madrid (spain) between 1977 and 1985. the incidence was high (1.3 cases per 1000 children admitted). the male/female ratio was 2:1. eight patients were under 2 years of age and 15 over 2 years, the majority being adolescents. the two groups presented marked etiological and p ...19902349146
polyclonal b cell hyperplasia associated with epstein-barr virus causing acute renal allograft failure.six weeks post cadaver renal transplantation, a patient developed a flu-like illness. acute renal failure unresponsive to anti-rejection therapy occurred and he died four days later from pneumocystis carinii pneumonia and streptococcus viridans septicemia. autopsy revealed a diffuse polymorphic polyclonal b cell infiltrate occupying most organs, including the allograft. primary epstein-barr virus (ebv) infection was established by 1) rising anti-ebv antibody titres; 2) the demonstration of ebv n ...19852994928
endocarditis associated with prosthetic cardiac valves.clinical features, microbiology, therapy and outcome of 26 episodes of prosthetic valve endocarditis occurring at westmead hospital from 1979 to 1989 were examined retrospectively. presentation with a new or changed cardiac murmur was associated with early onset infection (within 12 months of prosthetic valve insertion; p = 0.0033). corynebacteria were the commonest cause of early onset endocarditis (4 of 11 episodes) and streptococcus viridans of late onset endocarditis (4 of 15 episodes). nine ...19902381336
infectious crystalline keratopathy.a 76-year-old patient was found to have a crystalline keratopathy with no evidence of acute inflammation in her right corneal graft. the patient had been on long-term topical steroids. subsequent microscopy of the graft demonstrated pockets of gram-positive cocci with a paucity of inflammatory cells. this is the tenth reported case of infectious crystalline keratopathy, first reported by gorovoy in 1983. it does not always occur in corneal grafts, but the use of long-term topical steroids, toget ...19902390241
left atrial myxoma infected with streptococcus viridans.a case is described of streptococcus viridans endocarditis involving a left atrial myxoma. the diagnosis was made by echocardiography and the infected tumour was successfully treated by surgical removal. a review of the published literature about left atrial myxomas underlines the importance of performing echocardiography in all patients with suspected endocarditis.19883068157
the incidence of bacteremia associated with emergent intubation: relevance to prophylaxis against bacterial endocarditis.to examine the incidence of bacteremia associated with emergent nasotracheal intubation.19902398991
management of empyema thoracis.over a 5-year period, 65 adult patients with empyema thoracis were treated. the cause of the empyema was postpneumonic in 52%, postresectional in 24%, a complication of minor surgical procedures in 14%, posttraumatic in 5%, and the result of miscellaneous causes in 5%. in the postpneumonic group, infection resulted from a single aerobic organism in 41%, multiple aerobic organisms in 9%, single anaerobic organisms in 12%, and mixed aerobic-anaerobic organisms in 18%. peptostreptococcus, streptoco ...19902400254
survival of streptococcus viridans in gentamicin-supplemented mccarey-kaufman medium.our experience with three cases of streptococcus viridans endophthalmitis, following penetrating keratoplasty, prompted us to investigate the ability of gentamicin-supplemented mccarey-kaufman (m-k) medium to kill s. viridans contaminants. after inoculation of 20 cc of gentamicin-supplemented m-k with s. viridans, the m-k was exposed to temperature conditions similar to those that would be encountered by a donor cornea during storage (4 degrees c) and preoperative warming prior to keratoplasty ( ...19892496953
in vitro activity of ro 15-8074 and ro 19-5247.the in vitro activity of ro 15-8074 (cefetamet) and ro 19-5247, new oral cephalosporins, was compared with that of amoxicillin, cephalexin, cefaclor, cefuroxime and erythromycin against 292 clinical isolates using the agar dilution method. both ro 15-8074 and ro 19-5247 were very active against proteus mirabilis, neisseria gonorrhoeae, haemophilus influenzae and streptococcus pyogenes, but less active against staphylococcus saprophyticus and enterobacter cloacae. ro 19-5247 was more active than ...19873109897
[reducing vaginal flora by preoperative disinfection].in 70 gynaecological patients vaginal disinfection by povidone-iodine and chlorhexidine solution (lec) was investigated. the preoperative bacterial spectrum corresponded to the specifications in literature. only lactobacilli were found in fewer cases than expected, an effect, which was explained by the povidone-iodine sanitation of the vagina a day before the operation. in cases of disturbed lactobacilli flora, facultative pathogen species were found in high concentrations up to 10(6) cfu/ml. ge ...19912026302
[a clinical and experimental study of longatsef].data are reported of the results of clinical trials of the therapeutic efficacy of longaceph--a drug of the new generation of cephalosporins with a long period of half-decay--in acute pneumonia complicating influenza in 42 patients. the sensitivity of 120 microbial strains to longaceph was also studied. it was established that cephalosporin possesses a high efficacy in diseases caused by gram-positive and gram-negative microorganisms. a high degree of sensitivity to longaceph was observed in pne ...19892482583
[infectious endocarditis from the morphologic viewpoint: on the pathology and clinical aspects of 97 autopsy cases].in continuous autopsy material between 1978 and 1987 an infectious endocarditis was present in 97 cases of 8745 postmortem examinations. hospital acquired or iatrogenic infections were at the top of the list with 60% contribution and intravasal devices, cardiovascular or abdominal surgery acting as predominant entrance spots of the infection. in community acquired disease the portal of entry could not be ascertained in most of the cases. the spectrum of causative organisms showed staphylococcus ...19912030661
[bacteremia in febrile children].bacteremia in children under 2 years of age is not uncommon. several studies indicated that a small proportion of young children with fever who do not appear to be seriously ill may have bacteremia, and a small proportion of this subgroup may go on to develop serious illness such as meningitis. the rationale for this study was to assess both the incidence of bacteremia in febrile children in taipei area and the predictive value of the white blood cell count and degree of body temperature for bac ...19912039970
[clinical evaluation of sultamicillin in lower respiratory tract infections].clinical efficacy and safety of sultamicillin (sbtpc) in patients with lower respiratory tract infections, mainly pneumonia and bronchitis, have been evaluated in a multicenter trial by 19 institutions in the kyushu area during a period of 12 months from december 1988 to november 1989. 1. clinical evaluation was made in 132 patients and efficacy rates of sbtpc were 80.0% (28/35) for pneumonia, 78.5% (73/93) for bronchitis and 100% for the remaining 1 patient with other respiratory tract infectio ...19912041156
endocarditis in a cow.bacterial endocarditis of the tricuspid valve was diagnosed in a cow with weight loss, reduced milk production, and intermittent fever. clinical signs of disease included jugular and mammary vein pulses, tachycardia, large cardiac silhouette, and grade-iii/v holosystolic murmur. the diagnosis was also supported by echocardiographic findings and isolation of streptococcus viridans from blood samples. the cow was treated with penicillin, furosemide, acetylsalicylic acid, heparin, and potassium chl ...19912061158
cervical osteomyelitis due to i.v. heroin use: radiologic findings in 14 patients.we reviewed the radiographs of 14 patients who had cervical osteomyelitis and were iv heroin users. eleven were men and three were women. their age range was 33-48 years (mean, 39 years). eleven regularly used the jugular vein access, and three alternated between the jugular and femoral veins. initial radiographs of the cervical spine in 13 patients showed destruction of two or more vertebral bodies and the adjacent intervertebral disk, as well as a prevertebral soft-tissue mass. in one patient, ...19902115262
[endocarditis prophylaxis with amoxicillin, clindamycin or erythromycin? serum bacteriostatic and bactericidal effect against streptococcus viridans].the effectiveness of antibiotic prophylaxis against endocarditis was assessed by testing the bactericidal and bacteriostatic action in serum of 12 healthy volunteers who had taken the recommended antibiotics according to laid down guidelines. blood was obtained from these subjects every two hours for 12 hours after oral intake of amoxicillin (3 g as a single dose), clindamycin (600 mg a single dose) or erythromycin (1.5 g plus another 0.5 g after six hours), the serum being tested against three ...19883292185
splenic abscess: presentation, treatment options, and results.pyogenic splenic abscess is a rare condition that tends to occur in patients with predisposing factors. the use of splenectomy or computed tomography-guided percutaneous drainage in 10 patients with splenic abscess is presented. in 8 of 10 cases, the diagnosis was based on abdominal computed tomography scan. seven of 10 patients were treated with splenectomy, and 3 were managed with computed tomography-guided drainage. abscess cultures included escherichia coli, enterobacter, streptococcus virid ...19892589597
[endocarditis with ionescu-shiley's bioprosthesis. long-term results].with the aim to attesting the ability of treated pericardial tissue to resist infection we analyzed the incidence of prosthetic valve endocarditis in 541 operative survivors with the ionescu-shiley (i-s) valve since january 1977. a total of 580 valves were available for the study, 21 (3.8%) sustained i-s endocarditis or 0.65% patients/annum. the mean age was 53.2 years; male/female ratio was 16/5. native endocarditis was present in 20 cases (3.6%). there were 13 aortic endocarditis (2 in cases o ...19892623299
[infectious endocarditis in a healthy valve, arising from another valve].we report a case of isolated aortic regurgitation complicated by active infective endocarditis with streptococcus viridans as causative organism. the affected structure was a previous normal mitral valve.19892624508
[impact of infections on mortality in children with cancer].a study of the role infections play in the death of 29 children with cancer was conducted from 1983 to 1988. an infection was the main cause of death in twelve patients and was associated with hemorrhage in nine. five of the patients were free of infection at the time of their death. the most frequently found etiological agents found in hemocultures taken while still alive were: staphylococcus epidermidis, staphylococcus aureus, streptococcus viridans, salmonella enteritidis, escherichia coli, e ...19892627272
therapeutic efficacy of the combination of aztreonam with cefotaxime in the treatment of severe nosocomial pneumonia. comparative study against amikacin combined with cefotaxime.the combination aztreonam + cefotaxime (az + ce) was compared to amikacin + cefotaxime (am + ce) in the treatment of nosocomial pneumonia acquired at the intensive-care unit. this study included a total of 33 patients fulfilling criteria for nosocomial pneumonia. 16 of them were randomly allocated to the az + ce group and 17 to the am + ce group. the empirical treatment was effective for 78% of az + ce cases and 92% of am + ce cases (p = ns). clinical care was observed in 77% of cases (10 out of ...19892659289
quantitative bacteriology of a case of acute parotitis.it is generally assumed that the microorganisms responsible for acute suppurative parotitis are facultative anaerobes, primarily staphylococcus aureus and streptococcus viridans. a quantitative microbiologic investigation of an aspirate of pus from the case we report revealed a microbial flora (5.1 x 10(6) cfu/ml) consisting entirely of strict anaerobes (fusobacterium nucleatum and peptostreptococcus anaerobius). the strain of f. nucleatum was sensitive to metronidazole but resistant to penicill ...19892682427
respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans. 19892721663
[refractory anemia complicated by behçet's disease--report of three cases].three cases of refractory anemia (ra) are presented. they developed a complete, an intestinal, and an incomplete type of behçet's disease after 13 years, 6 months, and 4 years of illness, respectively. they showed normal or only slightly reduced neutrophil counts in spite of anemia and thrombocytopenia. although the precise etiology of behçet's disease is still obscure, it is suggested that immunological reactions against streptococcus viridans in chronic infection, and auto-oxidative damage ind ...19892769974
[production of experimental infective endocarditis in rabbit mitral valve prolapse induced by vagus stimulation].an experimental model of bacterial endocarditis was developed in rabbits with mitral valve prolapse which was induced by vagus stimulation. endocarditis was produced by injecting bacteria including pseudomonas pseudoalkaligenes (pathogenic for rabbits) and streptococcus viridans taken from human beings. both bacteria induced bacterial endocarditis with high incidence, which was augmented by higher dose or earlier administration of bacterial after producing mitral valve prolapse. similarly, verru ...19892778644
investigation of a streptococcus viridans pseudobacteremia epidemic at a university teaching hospital.for several months in 1986, an outbreak of streptococcus viridans pseudobacteremia occurred at a large teaching hospital. all sources of laboratory blood culture contamination were excluded. a retrospective epidemiological study indicated that one phlebotomist, "p," collected a disproportionate number of the positive blood cultures. further comparison of the paired blood culture results from the three months when the incidence was highest revealed a good concordance of results among all other ph ...19892794467
pharmacokinetic and in vivo studies with azithromycin (cp-62,993), a new macrolide with an extended half-life and excellent tissue distribution.azithromycin (cp-62,993), a new acid-stable 15-membered-ring macrolide, was well absorbed following oral administration in mice, rats, dogs, and cynomolgus monkeys. this compound exhibited a uniformly long elimination half-life and was distributed exceptionally well into all tissues. this extravascular penetration of azithromycin was demonstrated by tissue/plasma area-under-the-curve ratios ranging from 13.6 to 137 compared with ratios for erythromycin of 3.1 to 11.6. the significance of these p ...19872830841
pulsed doppler and two-dimensional echocardiographic findings in coronary arteriovenous fistula complicated by bacterial endocarditis. a case report.coronary arteriovenous fistula (cavf) may occasionally be complicated by bacterial endocarditis. the actual anatomical site of infection has not been clearly defined. a 13-year-old boy with a cavf and streptococcus viridans bacteraemia is described. the origin of the fistulous tract and a vegetation in close proximity to the distal drainage site into the right ventricle was demonstrated by doppler two-dimensional echocardiography.19892919328
[streptococcal abscesses of the liver: diagnosis and therapy using ultrasound controlled puncture].three male patients without accompanying diseases, 27, 47, and 52 years of age, were admitted with fever of unknown origin. focal liver disease was seen on ultrasound and the diagnosis of an abscess was confirmed by sonographically-guided fine-needle puncture. microaerophilic streptococci were found in two cases, streptococcus viridans once. two patients had cryptogenic abscesses; one had previously undergone surgery for a rectal abscess. all three patients were cured of their condition by appro ...19883047863
infective endocarditis in childhood.a total of 37 cases of infective endocarditis, in children aged two days to 13 years, were seen from 1971 to 1983 at the children's hospital, camperdown. structural heart disease was known to preexist in 95%. cyanotic congenital heart disease was present in 15 children, of whom 11 had been palliated by a systemic-to-pulmonary artery shunt. in five children, there was infection of a prosthetic valve. identifiable precipitants of infection were rare. in particular, no child had had a preceding den ...19863635143
relationship of surveillance cultures to bacteremia and fungemia in bone marrow transplant recipients with hickman or broviac catheters.a total of 64 episodes of bacteremia and fungemia were documented in 25 allogeneic bone marrow transplant recipients. coagulase-negative staphylococci were the most common pathogens recovered, with 34 of the 39 isolated being methicillin resistant. streptococcus viridans (11 episodes), diphtheroids (5 episodes), and pseudomonas aeruginosa (4 episodes) accounted for the majority of the other pathogens causing bacteremia. six episodes of fungemia were also seen. coagulase-negative staphylococci we ...19883054334
immunocompromised animal models for the study of antibiotic combinations.studies of various models of pseudomonas aeruginosa infections in neutropenic animals have demonstrated the superiority of the combination of beta-lactam and aminoglycoside antibiotics when compared with a single drug alone. a limited number of studies carried out in models of klebsiella pneumoniae infections in neutropenic animals have shown similar results. the efficacy of double beta-lactam combinations for the treatment of gram-negative bacillary infections has not been studied as extensivel ...19863087166
post-mortem bacterial culture of bronchial mucus and heart blood in hospital and non-hospital autopsies: effect of morgue time and length of hospitalization.we studied cultures of 109 bronchial mucus and 67 heart blood specimens from unselected hospital autopsies and 40 bronchial mucus and heart blood specimens from unselected non-hospital (forensic) autopsies, performed 1-11 days after death. the most prevalent bacterium was streptococcus viridans. no association was found between morgue time and the number of species isolated from each bronchial mucus or heart blood specimen in either hospital or non-hospital autopsies, nor between morgue time and ...19863096018
preterm labor: stimulation of arachidonic acid metabolism in human amnion cells by bacterial products.there is a strong association between preterm labor and infection. some potentially pathogenic bacteria have phospholipase activity, and it has been suggested that release of phospholipase from these organisms may increase prostaglandin e2 synthesis in amnion cells and hence initiate preterm labor. in this study we established monolayer amnion cell cultures from tissue collected at elective cesarean section at term before labor. cells were prelabeled with tritiated arachidonic acid and then furt ...19873103451
acanthamoeba keratitis and infectious crystalline keratopathy.two cases of acanthamoeba keratitis and infectious crystalline keratopathy, occurring simultaneously, are presented. three and 12 months after initiating topical corticosteroid therapy in cases 1 and 2, respectively, alpha-hemolytic streptococcus viridans was cultured from each cornea. topical corticosteroid therapy was initiated for the treatment of an annular stromal opacity, presumably secondary to herpes simplex keratitis. acanthamoeba was identified in culture following penetrating keratopl ...19873314824
corneal rim cultures.we performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. there were 82 positive cultures (39%), and the most common pathogen was staphylococcus epidermidis, with 24 positive cultures (30%). ten of these (42%) were resistant to gentamycin. there were no cases of endophthalmitis or other infections in the immediate postoperative period. we also found 15 positive cultures of streptococcus viridans. of these, 13 ( ...19873315460
infective endocarditis: incidence and mortality in the north east thames region.a survey of infective endocarditis in the north east thames regional health authority was carried out over a period of 30 months from 1982 to 1984. the incidence, clinical characteristics, and in-hospital mortality were studied. important causes of endocarditis were dental treatment, the presence of dental disease, drug abuse, and cytoscopy. the omission or incorrect administration of antibiotic prophylaxis in patients with valve disease was noted, but failure of correctly prescribed antibiotic ...19883342151
osteomyelitis of the distal phalanges in three children with severe atopic dermatitis.three children with severe, secondarily infected atopic dermatitis since infancy developed osteomyelitis of the distal phalanges of the hands. the insidious onset of one or more distal subungual black macules was followed by edema, erythema, and pain in the involved fingers. no child had an elevated erythrocyte sedimentation rate or fever, but all had roentgenographic or scintigraphic evidence of bony destruction. in two children, staphylococcus aureus grew from skin surface cultures; s aureus a ...19883345091
sudden death due to left coronary artery occlusion in infective endocarditis.a 44-year-old man died suddenly, shortly after admission to the hospital with complaints of abdominal pain. medical history was significant for chronic alcoholism and homozygous hemoglobin c disease. autopsy revealed vegetations on the aortic valve, especially on the left coronary cusp. there was anomalous origin of the coronary arteries from the left sinus of valsalva. the large vegetation on the left coronary cusp had extended into the left main-stem coronary artery and obstructed it. there wa ...19883415444
new concept in chemoprophylaxis of bacterial endocarditis resulting from dental treatment.bacteremia following dental procedures may lead to bacterial endocarditis in susceptible patients. traditional methods of chemoprophylaxis with a parenteral loading dose of penicillin followed by oral penicillin have proved impractical outside the hospital. in 1978, it was suggested in england that amoxicillin be substituted as the drug of choice in the prophylaxis of bacterial endocarditis. the recommended mode of treatment was a single oral dose of 3 g amoxicillin administered 1 hour before on ...19863458144
extracranial mycotic aneurysms in infective endocarditis.nine of 217 (4.15%) patients with infective endocarditis who were followed from october 1978 to february 1984 had extracranial mycotic aneurysms (ma). age range of patients was 6-43 years (mean of 24.8 years) and 7 were male. etiologic agents were streptococcus viridans (3 cases), staphylococcus aureus (2 cases), staphylococcus epidermidis (1 case), and pseudomonas aeruginosa (1 case). two patients had negative blood cultures. the ma involved the arteries of the limbs (5 cases), thoracic (3 case ...19863512135
infectious crystalline keratopathy.a 57-year-old white female was noted to have unusual intrastromal crystalline-like opacities in her failing right corneal graft five months after transplant surgery. cultures grew streptococcus viridans; since the graft was failing it was replaced and sent for pathologic examination. h&e stains revealed intrastromal pockets of basophilic material between the lamellae; there was a notable absence of inflammatory cells. gram's stain showed the basophilic material to be gram positive and transmissi ...19863529469
hemophilus influenzae and streptococcus viridans endocarditis in an intravenous drug abuser. 19863537870
propionibacteria isolates and asymptomatic infections of the peritoneal effluent in capd patients.during the past two years our laboratory has isolated propionibacterium-an anaerobic gram-positive rod-on 40 occasions from the drainage fluid of 25 patients on capd and eight on ipd. most patients had no symptoms and the fluid was sent for culture after treatment of peritonitis, during training period, and occasionally because it was cloudy. no association was found with patients' age, length on dialysis, or previous peritonitis episodes. the only statistically significant association (p = 0.03 ...19863110672
[preventive antibiotic administration in complicated rhinosurgical interventions--a double-blind study].revision rhinoplasty was performed in 100 patients. in most cases a complete rhinoplasty with septal reconstruction, osteotomies, wedge resection and free transplants had to be done. intranasal swabs for bacterial culture were taken pre- and postoperatively. 48 patients received three mega units of propicillin transorally for 12 days, 52 patients received a placebo. white blood count, erythrocyte sedimentation rate, and temperature were taken to indicate inflammation of the nasal region. turbid ...19883133529
[surgical aortic valve replacement for acute streptococcus viridans endocarditis with simultaneous moderate hemophilia a].this is a report of a 25-year-old patient with known aortic valve stenosis since early youth and hemophilia a, showing recurrent joint bleeding. acute streptococcus endocarditis induced aortic valve insufficiency resulting in cardiac failure. aortic valve replacement was performed after substitution of factor viii, during which intra- and postoperative bleeding was prolonged by pericardial adhesions. heparin was administered during cardiopulmonary-bypass as usual, but usual postoperative cumarin ...19883145652
multiple brain abscesses secondary to dental caries and severe periodontal disease.a case is reported in which an intra-oral focus of sepsis is thought to have resulted in the patient developing multiple brain abscesses without the presence of lung infection or cardiac valvular disease. the link between the two sites of infection is supported by the isolation of two streptococcus viridans species normally associated with dental caries and periodontal disease. the management of multiple brain abscesses is discussed.19883165021
infective endocarditis in children with congenital heart disease: the changing spectrum, 1965-85.thirty-five episodes of infective endocarditis in 35 children with congenital heart disease, from january 1965 to december 1984, were reviewed. the incidence of infective endocarditis in cyanotic congenital heart defects increased with a concomitant decrease in the frequency of lesions with left to right shunt. the incidence of postoperative endocarditis decreased from 1:52 during the first decade to 1:1033 during the second decade. the time interval between onset of symptoms and the establishme ...19883234417
management of catheter-related infections in pediatric patients.broviac catheters are commonly used to provide parenteral nutrition and access for infusion of blood products and drugs to pediatric patients. sepsis is the most common serious complication of continued catheter use. although removal of the catheter is generally recommended when it becomes contaminated, it may not be feasible to do so without compromising patient care. we evaluated the management of catheter-related infections in pediatric patients with and without removal of catheter. seventy-s ...19883278159
streptococcal endophthalmitis from contaminated donor corneas after keratoplasty. clinical and laboratory investigations.we report three cases of streptococcus viridans endophthalmitis following penetrating keratoplasty in which s viridans was cultured from the recipient eye, mccarey-kaufman (m-k) media, and corneoscleral rims. as a laboratory correlation, we investigated the ability of s viridans to survive in m-k medium supplemented with gentamicin. after m-k medium was inoculated with s viridans, it was stored overnight at 4 degrees c, after which the temperature was raised to 23 degrees c. periodic colony coun ...19883281643
[pleural empyema due to streptococcus milleri].thus far little attention has been focused on the precise identification of streptococcus viridans to species level and the clinical relevance of streptococcus milleri, yet there is growing evidence that closer identification would be of significant clinical value. streptococcus milleri was identified in 142 isolates from approximately 120 patients over a period of 12 months (june 1984-may 1985) at the institute of medical microbiology, zurich university hospital. pleural empyema was the source ...19873303315
[spondylitis caused by the non-hemolytic streptococcus viridans mitis]. 19863787842
infective endocarditis in children: a current diagnostic trend and the embolic complications.twenty-three cases of ie, of which 91% had underlying congenital heart diseases were diagnosed by positive blood culture or vegetative lesion detected by 2-d echo when a patient revealed clinically suspicious episodes. vsd and tof were the most common underlying heart diseases. the vegetation was detected successfully by 2-d echo in 91% of the cases. the causative organisms were identified in 83% of the cases. streptococcus viridans and staphylococcus aureus were the two major organisms detected ...19863820538
[extra-hospital streptococcus viridans pneumonia]. 19873821252
septic arthritis due to aerococcus viridans.a 20-year-old woman was found to have septic arthritis of the hip due to aerococcus viridans. this organism closely resembles streptococcus viridans, but forms gram positive tetrads rather than chains in broth media. the organism has been reported rarely to cause endocarditis and one case of osteomyelitis has been observed. to our knowledge septic arthritis due to aerococcus viridans has not been previously reported.19854087248
clinical evaluation of a fluorescent antibody test for the serological diagnosis of streptococcal endocarditis.serum fluorescent streptococcal antibody tests were carried out on 71 patients with clinically suspected infective endocarditis, and a final diagnosis of endocarditis was obtained in 46 patients. a serological diagnosis of streptococcal endocarditis was obtained in 10 patients who had persistently negative blood cultures, as fluorescent streptococcal antibody titres equal to or greater than 400 were detected against at least one of four strains of streptococci used as heterologous antigens. ther ...19853881479
immunofluorescence studies of cardiac valves in infective endocarditis.mitral and aortic valves removed at emergency cardiac surgery from a patient with infective endocarditis caused by streptococcus viridans were studied by immunofluorescence to ascertain the extent and pattern of various immune reactants within the large valvular vegetations. heavy intravalvular deposits of igg as well as bacterial antigen were present. much more focal interstitial igm and c3 deposits were noted within vegetations and valve substance. diffuse endocardial and subendocardial deposi ...19853883933
infective endocarditis in adults in glasgow, 1976-81.seventy-one cases of endocarditis in adults, defined on strict clinical criteria over a period of 5 years were studied. the demographic profile was similar to other published studies except that no bimodal peak in age distribution was detected. the major presenting features were infection, cardiac failure and embolism. rheumatic valvular disease (44%) was the most common predisposing condition. twenty percent of our patients developed endocarditis on an apparently normal valve and 28% presented ...19853886562
teeth and streptococcus viridans endocarditis. 19714103409
successful two-week treatment schedule for penicillin-susceptible streptococcus viridans endocarditis. 19714108262
current diagnosis of infective endocarditis.an analysis was made of 91 cases of infective endocarditis (ie) with regard to causative organisms and their sensitivities to various antibiotics, the clinical features of the disease, the laboratory test results and other items were important in establishing a diagnosis of ie. the number of cases of ie has shown a tendency to increase in recent years, particularly in the number of elderly patients, and the ratio of total cases consisting of prosthetic valve endocarditis (pve) has shown a sharp ...19853894710
[interactions between oral streptococci and staphylococci, with special reference to the inhibitory action of streptococcus viridans on staphylococcus]. 19744218255
[neonatal meningitis caused by streptococcus mitis].we report on a female newborn, 37 weeks of gestational age, who - after normal pregnancy and delivery - fell ill with a neonatal meningitis caused by streptococcus mitis. until now this bacillus has been thought to be apathogen. the disease was cured completely by penicillin therapy. the infection of a healthy newborn caused by streptococcus mitis, a streptococcus viridans, has not been described before.19853908918
bacteremia with gastrointestinal endoscopic procedures.the authors have reviewed 40 prospective studies of bacteremia with gastrointestinal procedures. endoscopic procedures with a low mean frequency of bacteremia were esophagogastroduodenoscopy (4.2%), endoscopic retrograde cholangiopancreatography (5.6%), colonoscopy (2.2%), and sigmoidoscopy (4.9%). a higher mean frequency of bacteremia was encountered with esophageal dilation (45%) and variceal sclerotherapy (31%), although the number of patients studied was small. potentially pathogenic organis ...19863533703
peritonitis due to streptococcus viridans in patients receiving continuous ambulatory peritoneal dialysis. 19853919872
[bacterial endocarditis caused by streptococcus viridans disclosed by sacroiliitis]. 19873563374
infective endocarditis in swedish children. i. incidence, etiology, underlying factors and port of entry of infection.a retrospective study of swedish children with infective endocarditis (ie) during the period 1971-80 was made. sixty-six instances were identified in 64 children (0.39 cases per 100,000 children per year). fifty (78%) had a previously known heart disease. most commonly this was a ventricular septal defect and tetralogy of fallot. seventy-one percent had positive blood cultures. streptococcus viridans and staphylococcus aureus were most commonly isolated. twenty-two percent of the children had un ...19863564983
factors influencing mortality from infective endocarditis in two district general hospitals.factors influencing mortality were studied in 92 consecutive cases of infective endocarditis admitted to two district general hospitals between january 1975 and april 1982. thirty two patients died, an overall mortality of 35%, 13 patients died before diagnosis and 19 despite aggressive antimicrobial therapy. bactericidal antibiotic levels were monitored in 39 cases but these did not appear to influence outcome. mortality was lowest for streptococcus viridans infection (15%) but rose to 50% for ...19873671266
role of the vegetation in experimental streptococcus viridans endocarditis.this study examines the role of the vegetation in catheter-induced experimental endocarditis in predisposing to bacterial colonization of cardiac valves and in influencing the course of the disease and response to penicillin therapy. platelet-fibrin vegetations developed at areas of valvular trauma and were colonized when streptococcus viridans were injected intravenously. pretreatment with warfarin prevented vegetation formation, but animals still developed endocarditis at the same rate after i ...19744497487
[identification of streptococcus viridans in clinical specimens].in a 4 year prospective study of "viridans" or non-groupable streptococci 100 clinically significant strains were isolated. strains were defined as significant when found in two or more samples of blood cultures, or when seen on gram staining together with inflammatory reaction. fifty-two strains were speciated by 10 physiological characteristics. in 42 cases additional tests were performed. only 16 isolates were unidentifiable by the techniques used. sources of isolates included purulent lesion ...19873685392
mitral valve aneurysm formation documented by cross-sectional echocardiography.we report a case of mitral valve aneurysm secondary to streptococcus viridans endocarditis of the mitral valve. cross-sectional echocardiography demonstrated an initial thickening of the anterior mitral leaflet which evolved further into an aneurysm. surgery showed that this lesion had subsequently perforated. this case highlights the ability of echocardiography to detect gradual anatomic changes in the course of bacterial endocarditis. the diagnosis of such abnormalities might have important th ...19863699053
immunosuppressive therapy and plasmapheresis in rapidly progressive glomerulonephritis associated with bacterial endocarditis.a 25-year-old male presented with new cardiac murmurs and acute renal insufficiency. blood cultures grew streptococcus viridans and appropriate antibiotic therapy was initiated. a renal biopsy revealed diffuse proliferative glomerulonephritis with crescents involving more than 50% of the glomeruli. treatment with antibiotics, plasmapheresis, and steroids resulted in renal recovery that paralleled reductions in circulating immune complexes. the rationale for this therapeutic approach is discussed ...19863706297
effect of chlorhexidine 0.5% on the hand bacterial flora.the effects of cleaning the dorsal hand with chlorhexidine 0.5% in spirit was evaluated by bacteriological study in 45 adult patients. in the absence of cleaning it was found that the prevalent microorganisms were staphylococcus epidermidis, staphylococcus aureus, streptococcus viridans and enterobacteriaceae. cleaning the hand with chlorhexidine 0.5% eliminated all bacteria except s. epidermidis and s. aureus. in both instances, the culture results showed that the microorganisms were present in ...19863776454
infective endocarditis in children.the clinical manifestations, infective microorganisms, underlying diseases, complications and prognosis of infective endocarditis (ie) were studied in 17 current patients. data were compared with 101 previous cases reported in japan. most patients with ie (110/118 = 93.2%) had underlying heart diseases. ie was noted most often in patients with ventricular septal defect (vsd) and tetralogy of fallot. the incidence of post operative endocarditis was high (29.4% in the present series and 9.0% in th ...19854021067
penicillin-aminoglycoside synergy in experimental streptococcus viridans endocarditis. 19744823583
serious infection in a neonatal intensive care unit: a two-year survey.over a two-year period 160 episodes of serious infection occurred in 139 infants admitted to a regional neonatal intensive-care unit. eighty-seven (26%) of very low birth weight (vlbw) neonates and 52 (8%) of infants of birth weight greater than 1500 g were infected. the majority (84%) had bacteraemia alone. though the clinical features of infection were not distinctive, in 94% of episodes the peripheral white blood cell or band counts were abnormal. thirty-three (21%) of the infections occurred ...19854067290
studies on bacteriocinogeny of streptococcus strains. i. bacteriocinogeny of strains of the streptococcus viridans group. 19714933384
[antibiotic-resistance of strains of streptococcus viridans, streptococcus faecalis, escherichia coli, pseudomonas aeruglinosa, proteus sp., and klebsiella sp. isolated in poland in 1960-1963]. 19654955331
[study of the antigenic substances of streptococcus viridans]. 19654958239
[comparison of the antibiotic resistance of strains of streptococcus viridans, streptococcus faecalis, klebsiella, escherichia coli, pseudomonas aeruginosa and proteus isolated in poland in 1960-1963]. 19674964317
in-vitro comparison of erythromycin, lincomycin, and clindamycin.the in-vitro antibacterial activities of erythromycin, lincomycin, and clindamycin, a new derivative of lincomycin, were compared. clindamycin was always more active than lincomycin, and was either as active as erythromycin or more so against betahaemolytic streptococci, streptococcus viridans, str. pneumoniae, and erythromycin-sensitive staphylococcus aureus. it was also fully active against most erythromycin-resistant strains of staph. aureus. on the other hand, it was somewhat less active tha ...19704988120
streptococcus viridans and streptococcus faecalis endocarditis. 19704994139
dental bacteremia--a neglected cause of arthroplasty infections? three hip cases.we report on three patients with late hip replacement infection. the micro-organism was microaerophilic streptococcus viridans, an oral organism, in all patients. dental procedures had preceded the onset of the hip infection in all cases, and severe periodontal disease was observed on subsequent admissions.19854090954
dental status and recurrence of streptococcus viridans endocarditis. 19714103077
should good teeth be extracted to prevent streptococcus viridans endocarditis? 19714103078
influence of the alternate complement pathway in opsonization of several bacterial species.in normal human serum chelated with magnesium (10 mm) and ethylene glycotetraacetic acid (10 mm) (mgegta), the classical pathway of complement activation is blocked; however, the alternate pathway of complement activation is intact. diplococcus pneumoniae, staphylococcus albus, streptococcus viridans, streptococcus faecalis, and serratia marcescens were opsonized in normal human serum containing 10 mm mgegta. in contrast, staphylococcus aureus and pseudomonas aeruginosa were poorly opsonized in ...19744152919
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