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[waterhouse-friderichsen syndrome in adults].only a minority of published cases of waterhouse-friderichsen-syndrome occurred in adults (harms et al., 1973). at the autopsy of a 23 years old woman there were found sugillations of the eyelid, of the peri- and epicard, of the serosa of the small intestine and of the lung. in the region of the adrenal gland a brownish-red mass was detectable. histologically an adrenal apoplexy with necrosis and in liver, spleen and lung a lot of neutrophils were seen. streptococcus viridans was pointed out in ...19902241795
suture-wick endophthalmitis with sutured posterior chamber intraocular lenses.a patient had a corneal transplant with removal of an anterior chamber lens. as part of the procedure, an exchange posterior chamber lens was inserted and sutured transsclerally into the ciliary sulcus with two subconjunctival 10-0 polypropylene (prolene) sutures. one month later the patient experienced a sudden decrease in vision and severe eye pain. streptococcus viridans was cultured from the vitreous tap and the eye eventually was lost from this endophthalmitis. the infecting organism appear ...19902258814
septic arthritis due to streptococcus viridans. 19902261714
ceftriaxone monotherapy for bacterial meningitis in children.a total of 33 patients with bacterial meningitis were treated with single daily doses of ceftriaxone (ctr 100 mg/kg/day i.v.) for a median duration of 13 days. pathogens isolated by culture and/or determined by latex agglutination were 15 haemophilus influenzae b, 7 neisseria meningitidis, 2 streptococcus pneumoniae, 1 group b streptococcus, 2 streptococcus viridans and 2 staphylococcus epidermidis. in 4 cases a diagnosis of purulent meningitis could only be made by means of the inflammatory liq ...19902292206
infectious crystalline keratopathy associated with topical anesthetic abuse.two patients with infectious crystalline keratopathy associated with topical anesthetic abuse are described. no previously reported predisposing factors existed, including topical corticosteroid use during active herpes simplex or acanthamoeba keratitis, or following penetrating keratoplasty. cultures from corneal biopsies of both patients grew streptococcus viridans. both infections resulted in corneal scarring with vascularization. ultimately, corneal transplantation was performed in one case.19902297999
quantitative bacteriology of a case of acute parotitis.it is generally assumed that the microorganisms responsible for acute suppurative parotitis are facultative anaerobes, primarily staphylococcus aureus and streptococcus viridans. a quantitative microbiologic investigation of an aspirate of pus from the case we report revealed a microbial flora (5.1 x 10(6) cfu/ml) consisting entirely of strict anaerobes (fusobacterium nucleatum and peptostreptococcus anaerobius). the strain of f. nucleatum was sensitive to metronidazole but resistant to penicill ...19892682427
[streptococcus viridans and respiratory failure in acute leukemia].through the last 18 months, five of our patients with acute leukaemia have developed septicaemia caused by streptococcus viridans, followed by acute respiratory failure. two patients had to be placed in a respirator. in patients with acute leukaemia treated with cytostatic drugs, close clinical observation, including repeated blood gas analysis, is very important if they develop septicaemia caused by streptococcus viridans. early administration of high doses of corticosteroids seems to be import ...19902300957
[refractory anemia complicated by behçet's disease--report of three cases].three cases of refractory anemia (ra) are presented. they developed a complete, an intestinal, and an incomplete type of behçet's disease after 13 years, 6 months, and 4 years of illness, respectively. they showed normal or only slightly reduced neutrophil counts in spite of anemia and thrombocytopenia. although the precise etiology of behçet's disease is still obscure, it is suggested that immunological reactions against streptococcus viridans in chronic infection, and auto-oxidative damage ind ...19892769974
endocarditis associated with prosthetic cardiac valves.clinical features, microbiology, therapy and outcome of 26 episodes of prosthetic valve endocarditis occurring at westmead hospital from 1979 to 1989 were examined retrospectively. presentation with a new or changed cardiac murmur was associated with early onset infection (within 12 months of prosthetic valve insertion; p = 0.0033). corynebacteria were the commonest cause of early onset endocarditis (4 of 11 episodes) and streptococcus viridans of late onset endocarditis (4 of 15 episodes). nine ...19902381336
infectious crystalline keratopathy.a 76-year-old patient was found to have a crystalline keratopathy with no evidence of acute inflammation in her right corneal graft. the patient had been on long-term topical steroids. subsequent microscopy of the graft demonstrated pockets of gram-positive cocci with a paucity of inflammatory cells. this is the tenth reported case of infectious crystalline keratopathy, first reported by gorovoy in 1983. it does not always occur in corneal grafts, but the use of long-term topical steroids, toget ...19902390241
the incidence of bacteremia associated with emergent intubation: relevance to prophylaxis against bacterial endocarditis.to examine the incidence of bacteremia associated with emergent nasotracheal intubation.19902398991
bacterial antigens stimulate the production of histamine releasing factor (hrf) by lymphocytes from intrinsic asthmatic patients.lymphocyte from 12 intrinsic asthmatic patients and 10 healthy controls were studied for their capability to produce histamine releasing factor (hrf) in vitro. spontaneous hrf production was measured by culturing the lymphocytes alone for 20 h. in another set of experiments lymphocytes were first preincubated separately with phytohaemagglutinin, antigens of haemophilus influenzae, streptococcus viridans, staphylococcus sp. and neisseria catarrhalis for 4 h then carefully washed three times and c ...19862420497
pharmacokinetic and in vivo studies with azithromycin (cp-62,993), a new macrolide with an extended half-life and excellent tissue distribution.azithromycin (cp-62,993), a new acid-stable 15-membered-ring macrolide, was well absorbed following oral administration in mice, rats, dogs, and cynomolgus monkeys. this compound exhibited a uniformly long elimination half-life and was distributed exceptionally well into all tissues. this extravascular penetration of azithromycin was demonstrated by tissue/plasma area-under-the-curve ratios ranging from 13.6 to 137 compared with ratios for erythromycin of 3.1 to 11.6. the significance of these p ...19872830841
bacteriological quality of raw human milk: effect of storage in a refrigerator.eighty-seven breast milk samples were obtained from 63 mothers of infants on the neonatal intensive care unit of the lagos university teaching hospital. the samples were cultured for bacteria immediately after collection (0 h) and then stored in a domestic refrigerator from where cultures were repeated at 6-hourly intervals for 24 h. at 0 h, three (3.4%) of the samples were sterile; 56 (64%) grew coagulase negative staphylococci, and one (1.1%) streptococcus viridans. thus, 60 (69%) of the sampl ...19872449844
polyclonal b cell hyperplasia associated with epstein-barr virus causing acute renal allograft failure.six weeks post cadaver renal transplantation, a patient developed a flu-like illness. acute renal failure unresponsive to anti-rejection therapy occurred and he died four days later from pneumocystis carinii pneumonia and streptococcus viridans septicemia. autopsy revealed a diffuse polymorphic polyclonal b cell infiltrate occupying most organs, including the allograft. primary epstein-barr virus (ebv) infection was established by 1) rising anti-ebv antibody titres; 2) the demonstration of ebv n ...19852994928
endotracheal aspiration for the bacteriological diagnosis of nosocomial- and measles-associated pneumonia.endotracheal aspirates were obtained from 51 young children for the microbiological diagnosis of pneumonia acquired in hospital or associated with measles or severe protein-energy malnutrition. the procedure proved safe and the information obtained assisted in the management of most cases. there was a fairly good correlation between the findings of gram stain and those of culture of the aspirates, which improved when only gram stains showing many or moderate numbers of bacteria were used. the ba ...19882467606
relationship of surveillance cultures to bacteremia and fungemia in bone marrow transplant recipients with hickman or broviac catheters.a total of 64 episodes of bacteremia and fungemia were documented in 25 allogeneic bone marrow transplant recipients. coagulase-negative staphylococci were the most common pathogens recovered, with 34 of the 39 isolated being methicillin resistant. streptococcus viridans (11 episodes), diphtheroids (5 episodes), and pseudomonas aeruginosa (4 episodes) accounted for the majority of the other pathogens causing bacteremia. six episodes of fungemia were also seen. coagulase-negative staphylococci we ...19883054334
histamine release from human pulmonary mast cells induced by bacterial antigens.antigens of four bacteria (staphylococcus aureus, haemophilus influenzae, streptococcus viridans, branhamella catarrhalis) were tested for their ability to release histamine from human pulmonary mast cells recovered by means of bronchoalveolar lavages. for the sake of comparison the action of bacterial antigens on human mesenteric and adenoidal mast cells obtained by enzymatic dispersion of the tissues was studied. bal mast cells released histamine in response to all studied bacterial antigens. ...19882468267
[neonatal conjunctivitis in a nursery and a neonatal unit].after credé prophylaxis was abandoned at our hospital in 1984 scrupulous clinical surveillance of all neonates for conjunctivitis, and bacterial cultures from purulent eye discharge, have become routine. during the two-year period 1 march 1987 to 28 february 1989, testing for chlamydia trachomatis (eia-technique) was added in all infants with clinical conjunctivitis. during the period concerned there were 332 cases of conjunctivitis among 4,520 live born infants, an incidence of 7.3%. the incide ...19912042130
endocarditis in a cow.bacterial endocarditis of the tricuspid valve was diagnosed in a cow with weight loss, reduced milk production, and intermittent fever. clinical signs of disease included jugular and mammary vein pulses, tachycardia, large cardiac silhouette, and grade-iii/v holosystolic murmur. the diagnosis was also supported by echocardiographic findings and isolation of streptococcus viridans from blood samples. the cow was treated with penicillin, furosemide, acetylsalicylic acid, heparin, and potassium chl ...19912061158
abnormal maxillary sinus radiographs in children: do they represent bacterial infection?thirty-three children with chronic tonsillitis and/or adenoid enlargement and without previous diagnosis of sinusitis were studied regarding the bacterial flora of their maxillary sinuses. puncture of maxillary sinus was performed at surgery (adenoidectomy and/or tonsillectomy) and aspirates were cultured. streptococcus pneumoniae was isolated from 8 of 12 (66.7%) patients whose x-rays showed completely opacified maxillary sinus. streptococcus viridans, streptococcus faecalis, and staphylococcus ...19902107515
cervical osteomyelitis due to i.v. heroin use: radiologic findings in 14 patients.we reviewed the radiographs of 14 patients who had cervical osteomyelitis and were iv heroin users. eleven were men and three were women. their age range was 33-48 years (mean, 39 years). eleven regularly used the jugular vein access, and three alternated between the jugular and femoral veins. initial radiographs of the cervical spine in 13 patients showed destruction of two or more vertebral bodies and the adjacent intervertebral disk, as well as a prevertebral soft-tissue mass. in one patient, ...19902115262
infective endocarditis: a prospective study of 60 consecutive cases.sixty cases of infective endocarditis were studied prospectively between may, 1985 and december, 1988. there were 40 males and 20 females with a mean age of 28 years. endocarditis was found on normal valves in 13 patients, on rheumatic valves in 30, on congenital lesions in 8, on prosthetic valves in 4 and on mitral valve prolapse in 5 cases. positive blood cultures were detected in 35 patients (58%). in addition bone marrow culture was positive in 1 and valves removed on surgery grew causative ...19902132422
[preventive antibiotic administration in complicated rhinosurgical interventions--a double-blind study].revision rhinoplasty was performed in 100 patients. in most cases a complete rhinoplasty with septal reconstruction, osteotomies, wedge resection and free transplants had to be done. intranasal swabs for bacterial culture were taken pre- and postoperatively. 48 patients received three mega units of propicillin transorally for 12 days, 52 patients received a placebo. white blood count, erythrocyte sedimentation rate, and temperature were taken to indicate inflammation of the nasal region. turbid ...19883133529
streptococcus viridans osteomyelitis with endocarditis presenting as acute onset lower back pain.an elderly male with a history of diabetes mellitus and a recent dental procedure presented to the emergency department with acute lumbosacral pain and low grade fever. computerized tomography (ct scan) and magnetic resonance imaging (mri) yielded a presumptive diagnosis of pyogenic vertebral osteomyelitis. a diagnosis of viridans streptococcus vertebral osteomyelitis was confirmed by gallium scanning and blood culture. the literature has emphasized the occurrence of pyogenic vertebral osteomyel ...19902142706
the role of skin testing for penicillin allergy.skin testing for penicillin allergy is an imperfect predictor of severe allergic reactions. we used decision analysis to identify the types of allergy history for which skin testing should alter management. the treatment threshold, the probability of a serious allergic reaction at which point one should switch from penicillin to another antibiotic, depends on the quality of life associated with the clinical outcomes. we measured 12 physicians' attitudes toward the outcomes of treatment with peni ...19902203324
infective endocarditis in children with congenital heart disease: the changing spectrum, 1965-85.thirty-five episodes of infective endocarditis in 35 children with congenital heart disease, from january 1965 to december 1984, were reviewed. the incidence of infective endocarditis in cyanotic congenital heart defects increased with a concomitant decrease in the frequency of lesions with left to right shunt. the incidence of postoperative endocarditis decreased from 1:52 during the first decade to 1:1033 during the second decade. the time interval between onset of symptoms and the establishme ...19883234417
splenic abscess: presentation, treatment options, and results.pyogenic splenic abscess is a rare condition that tends to occur in patients with predisposing factors. the use of splenectomy or computed tomography-guided percutaneous drainage in 10 patients with splenic abscess is presented. in 8 of 10 cases, the diagnosis was based on abdominal computed tomography scan. seven of 10 patients were treated with splenectomy, and 3 were managed with computed tomography-guided drainage. abscess cultures included escherichia coli, enterobacter, streptococcus virid ...19892589597
[endocarditis with ionescu-shiley's bioprosthesis. long-term results].with the aim to attesting the ability of treated pericardial tissue to resist infection we analyzed the incidence of prosthetic valve endocarditis in 541 operative survivors with the ionescu-shiley (i-s) valve since january 1977. a total of 580 valves were available for the study, 21 (3.8%) sustained i-s endocarditis or 0.65% patients/annum. the mean age was 53.2 years; male/female ratio was 16/5. native endocarditis was present in 20 cases (3.6%). there were 13 aortic endocarditis (2 in cases o ...19892623299
diagnostic flexible bronchoscopy in human immunodeficiency virus (hiv)-positive children.twelve children with laboratory evidence of human immunodeficiency virus (hiv) infection underwent diagnostic flexible bronchoscopy with washings or bronchoalveolar lavage at bellevue hospital center from october 1987 to april 1989. the patients included 7 boys and 5 girls ranging from age 3.5 months to 10 years 5 months. indications for bronchoscopy included respiratory distress with or without focal changes on chest radiograph in 11 patients, and persistent but asymptomatic right middle lobe c ...19892625388
[impact of infections on mortality in children with cancer].a study of the role infections play in the death of 29 children with cancer was conducted from 1983 to 1988. an infection was the main cause of death in twelve patients and was associated with hemorrhage in nine. five of the patients were free of infection at the time of their death. the most frequently found etiological agents found in hemocultures taken while still alive were: staphylococcus epidermidis, staphylococcus aureus, streptococcus viridans, salmonella enteritidis, escherichia coli, e ...19892627272
bacterial endocarditis in children: clinical and laboratory findings, and the role of echocardiography in its diagnosis and management.we report clinical and laboratory findings of 15 children with bacterial endocarditis, admitted to the department of child health, university of indonesia/cipto mangunkusumo hospital from february, 1987 to june, 1989. there were 8 boys and 7 girls with bacterial endocarditis, ranging in age from 10 weeks to 16 years. the diagnosis was suspected because of prolonged fever, with or without other manifestations, i.e. congestive heart failure, refractory anemia, or paroxysmal atrial tachycardia. the ...19892631025
a clinical evaluation of sulbactam/ampicillin in the treatment of pediatric infections.we have treated 42 episodes of pediatric infections with sulbactam/ampicillin since 1987. included were 9 cellulitis, 9 urinary tract infections, 5 cervical lymphadenitis, 4 meningitis, 2 thoracic empyema, 2 osteomyelitis, 2 sepsis, 1 furuncle, 1 perianal abscess, 1 dental abscess, 1 peritonsillitis, 1 salmonellosis, 1 shigellosis, 1 peritonitis, 1 suppurative thyroiditis, 1 infective endocarditis. responsible pathogens were escherichia coli in 8, staphylococcus aureus in 6, hemophilus influenza ...19892637593
therapeutic efficacy of the combination of aztreonam with cefotaxime in the treatment of severe nosocomial pneumonia. comparative study against amikacin combined with cefotaxime.the combination aztreonam + cefotaxime (az + ce) was compared to amikacin + cefotaxime (am + ce) in the treatment of nosocomial pneumonia acquired at the intensive-care unit. this study included a total of 33 patients fulfilling criteria for nosocomial pneumonia. 16 of them were randomly allocated to the az + ce group and 17 to the am + ce group. the empirical treatment was effective for 78% of az + ce cases and 92% of am + ce cases (p = ns). clinical care was observed in 77% of cases (10 out of ...19892659289
osteomyelitis of the distal phalanges in three children with severe atopic dermatitis.three children with severe, secondarily infected atopic dermatitis since infancy developed osteomyelitis of the distal phalanges of the hands. the insidious onset of one or more distal subungual black macules was followed by edema, erythema, and pain in the involved fingers. no child had an elevated erythrocyte sedimentation rate or fever, but all had roentgenographic or scintigraphic evidence of bony destruction. in two children, staphylococcus aureus grew from skin surface cultures; s aureus a ...19883345091
respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans. 19892721663
new concept in chemoprophylaxis of bacterial endocarditis resulting from dental treatment.bacteremia following dental procedures may lead to bacterial endocarditis in susceptible patients. traditional methods of chemoprophylaxis with a parenteral loading dose of penicillin followed by oral penicillin have proved impractical outside the hospital. in 1978, it was suggested in england that amoxicillin be substituted as the drug of choice in the prophylaxis of bacterial endocarditis. the recommended mode of treatment was a single oral dose of 3 g amoxicillin administered 1 hour before on ...19863458144
[production of experimental infective endocarditis in rabbit mitral valve prolapse induced by vagus stimulation].an experimental model of bacterial endocarditis was developed in rabbits with mitral valve prolapse which was induced by vagus stimulation. endocarditis was produced by injecting bacteria including pseudomonas pseudoalkaligenes (pathogenic for rabbits) and streptococcus viridans taken from human beings. both bacteria induced bacterial endocarditis with high incidence, which was augmented by higher dose or earlier administration of bacterial after producing mitral valve prolapse. similarly, verru ...19892778644
infectious crystalline keratopathy.a 57-year-old white female was noted to have unusual intrastromal crystalline-like opacities in her failing right corneal graft five months after transplant surgery. cultures grew streptococcus viridans; since the graft was failing it was replaced and sent for pathologic examination. h&e stains revealed intrastromal pockets of basophilic material between the lamellae; there was a notable absence of inflammatory cells. gram's stain showed the basophilic material to be gram positive and transmissi ...19863529469
bacteremia with gastrointestinal endoscopic procedures.the authors have reviewed 40 prospective studies of bacteremia with gastrointestinal procedures. endoscopic procedures with a low mean frequency of bacteremia were esophagogastroduodenoscopy (4.2%), endoscopic retrograde cholangiopancreatography (5.6%), colonoscopy (2.2%), and sigmoidoscopy (4.9%). a higher mean frequency of bacteremia was encountered with esophageal dilation (45%) and variceal sclerotherapy (31%), although the number of patients studied was small. potentially pathogenic organis ...19863533703
hemophilus influenzae and streptococcus viridans endocarditis in an intravenous drug abuser. 19863537870
[bacterial endocarditis caused by streptococcus viridans disclosed by sacroiliitis]. 19873563374
primary streptococcus viridans pneumonia.we describe three cases of acute uncomplicated bacterial pneumonia due to viridans streptococci in previously healthy adults, which were indistinguishable from those caused by other well-known respiratory pathogens. on arrival, all of these patients were treated with iv aqueous penicillin based on gram stain of sputum which showed predominant gram-positive cocci in pairs and chains. these specimens of sputum grew normal oral flora in the three cases. the diagnosis was confirmed by positive blood ...19892791680
infective endocarditis in childhood.a total of 37 cases of infective endocarditis, in children aged two days to 13 years, were seen from 1971 to 1983 at the children's hospital, camperdown. structural heart disease was known to preexist in 95%. cyanotic congenital heart disease was present in 15 children, of whom 11 had been palliated by a systemic-to-pulmonary artery shunt. in five children, there was infection of a prosthetic valve. identifiable precipitants of infection were rare. in particular, no child had had a preceding den ...19863635143
bacteriology of unheated expressed breast milk stored at room temperature.thirty samples of unheated expressed breast milk (ebm) from thirty lactating mothers, stored at room temperature (rt) and in the refrigerator (at +4 degrees c), were examined for the degree of bacterial contamination at two hourly intervals upto eight hours. all the ebm samples contained bacteria, mostly of normal skin flora; staphylococcus albus 76.7%; streptococcus viridans 40%. potential pathogens were isolated in small numbers: escherichia coli 26%, streptococcus faecalis 13.6% and staphyloc ...19892791942
investigation of a streptococcus viridans pseudobacteremia epidemic at a university teaching hospital.for several months in 1986, an outbreak of streptococcus viridans pseudobacteremia occurred at a large teaching hospital. all sources of laboratory blood culture contamination were excluded. a retrospective epidemiological study indicated that one phlebotomist, "p," collected a disproportionate number of the positive blood cultures. further comparison of the paired blood culture results from the three months when the incidence was highest revealed a good concordance of results among all other ph ...19892794467
pulsed doppler and two-dimensional echocardiographic findings in coronary arteriovenous fistula complicated by bacterial endocarditis. a case report.coronary arteriovenous fistula (cavf) may occasionally be complicated by bacterial endocarditis. the actual anatomical site of infection has not been clearly defined. a 13-year-old boy with a cavf and streptococcus viridans bacteraemia is described. the origin of the fistulous tract and a vegetation in close proximity to the distal drainage site into the right ventricle was demonstrated by doppler two-dimensional echocardiography.19892919328
[streptococcal abscesses of the liver: diagnosis and therapy using ultrasound controlled puncture].three male patients without accompanying diseases, 27, 47, and 52 years of age, were admitted with fever of unknown origin. focal liver disease was seen on ultrasound and the diagnosis of an abscess was confirmed by sonographically-guided fine-needle puncture. microaerophilic streptococci were found in two cases, streptococcus viridans once. two patients had cryptogenic abscesses; one had previously undergone surgery for a rectal abscess. all three patients were cured of their condition by appro ...19883047863
[a clinical and experimental study of longatsef].data are reported of the results of clinical trials of the therapeutic efficacy of longaceph--a drug of the new generation of cephalosporins with a long period of half-decay--in acute pneumonia complicating influenza in 42 patients. the sensitivity of 120 microbial strains to longaceph was also studied. it was established that cephalosporin possesses a high efficacy in diseases caused by gram-positive and gram-negative microorganisms. a high degree of sensitivity to longaceph was observed in pne ...19892482583
survival of streptococcus viridans in gentamicin-supplemented mccarey-kaufman medium.our experience with three cases of streptococcus viridans endophthalmitis, following penetrating keratoplasty, prompted us to investigate the ability of gentamicin-supplemented mccarey-kaufman (m-k) medium to kill s. viridans contaminants. after inoculation of 20 cc of gentamicin-supplemented m-k with s. viridans, the m-k was exposed to temperature conditions similar to those that would be encountered by a donor cornea during storage (4 degrees c) and preoperative warming prior to keratoplasty ( ...19892496953
infective endocarditis in children: a current diagnostic trend and the embolic complications.twenty-three cases of ie, of which 91% had underlying congenital heart diseases were diagnosed by positive blood culture or vegetative lesion detected by 2-d echo when a patient revealed clinically suspicious episodes. vsd and tof were the most common underlying heart diseases. the vegetation was detected successfully by 2-d echo in 91% of the cases. the causative organisms were identified in 83% of the cases. streptococcus viridans and staphylococcus aureus were the two major organisms detected ...19863820538
[extra-hospital streptococcus viridans pneumonia]. 19873821252
streptococcal endophthalmitis from contaminated donor corneas after keratoplasty. clinical and laboratory investigations.we report three cases of streptococcus viridans endophthalmitis following penetrating keratoplasty in which s viridans was cultured from the recipient eye, mccarey-kaufman (m-k) media, and corneoscleral rims. as a laboratory correlation, we investigated the ability of s viridans to survive in m-k medium supplemented with gentamicin. after m-k medium was inoculated with s viridans, it was stored overnight at 4 degrees c, after which the temperature was raised to 23 degrees c. periodic colony coun ...19883281643
[endocarditis prophylaxis with amoxicillin, clindamycin or erythromycin? serum bacteriostatic and bactericidal effect against streptococcus viridans].the effectiveness of antibiotic prophylaxis against endocarditis was assessed by testing the bactericidal and bacteriostatic action in serum of 12 healthy volunteers who had taken the recommended antibiotics according to laid down guidelines. blood was obtained from these subjects every two hours for 12 hours after oral intake of amoxicillin (3 g as a single dose), clindamycin (600 mg a single dose) or erythromycin (1.5 g plus another 0.5 g after six hours), the serum being tested against three ...19883292185
infective endocarditis in adults in glasgow, 1976-81.seventy-one cases of endocarditis in adults, defined on strict clinical criteria over a period of 5 years were studied. the demographic profile was similar to other published studies except that no bimodal peak in age distribution was detected. the major presenting features were infection, cardiac failure and embolism. rheumatic valvular disease (44%) was the most common predisposing condition. twenty percent of our patients developed endocarditis on an apparently normal valve and 28% presented ...19853886562
current diagnosis of infective endocarditis.an analysis was made of 91 cases of infective endocarditis (ie) with regard to causative organisms and their sensitivities to various antibiotics, the clinical features of the disease, the laboratory test results and other items were important in establishing a diagnosis of ie. the number of cases of ie has shown a tendency to increase in recent years, particularly in the number of elderly patients, and the ratio of total cases consisting of prosthetic valve endocarditis (pve) has shown a sharp ...19853894710
[pleural empyema due to streptococcus milleri].thus far little attention has been focused on the precise identification of streptococcus viridans to species level and the clinical relevance of streptococcus milleri, yet there is growing evidence that closer identification would be of significant clinical value. streptococcus milleri was identified in 142 isolates from approximately 120 patients over a period of 12 months (june 1984-may 1985) at the institute of medical microbiology, zurich university hospital. pleural empyema was the source ...19873303315
acanthamoeba keratitis and infectious crystalline keratopathy.two cases of acanthamoeba keratitis and infectious crystalline keratopathy, occurring simultaneously, are presented. three and 12 months after initiating topical corticosteroid therapy in cases 1 and 2, respectively, alpha-hemolytic streptococcus viridans was cultured from each cornea. topical corticosteroid therapy was initiated for the treatment of an annular stromal opacity, presumably secondary to herpes simplex keratitis. acanthamoeba was identified in culture following penetrating keratopl ...19873314824
corneal rim cultures.we performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. there were 82 positive cultures (39%), and the most common pathogen was staphylococcus epidermidis, with 24 positive cultures (30%). ten of these (42%) were resistant to gentamycin. there were no cases of endophthalmitis or other infections in the immediate postoperative period. we also found 15 positive cultures of streptococcus viridans. of these, 13 ( ...19873315460
mitral obstruction in bacterial endocarditis.mitral obstruction due to a large vegetation of acute streptococcus viridans endocarditis occurred in a 47 year old man. serial echocardiography documented the rapid growth of the vegetation and its haemodynamic effects. emergency mitral valve replacement was performed too late to reverse the course of fatal septic shock.19853970792
infective endocarditis: incidence and mortality in the north east thames region.a survey of infective endocarditis in the north east thames regional health authority was carried out over a period of 30 months from 1982 to 1984. the incidence, clinical characteristics, and in-hospital mortality were studied. important causes of endocarditis were dental treatment, the presence of dental disease, drug abuse, and cytoscopy. the omission or incorrect administration of antibiotic prophylaxis in patients with valve disease was noted, but failure of correctly prescribed antibiotic ...19883342151
streptococcus viridans vertebral osteomyelitis with bacteremia. 19853980198
[cause, facilitation or accident: haemophilus and streptococcus viridans polymicrobial endocarditis]. 19853982141
streptococcus viridans bacteremia associated with atrial myxoma. 19854013981
sudden death due to left coronary artery occlusion in infective endocarditis.a 44-year-old man died suddenly, shortly after admission to the hospital with complaints of abdominal pain. medical history was significant for chronic alcoholism and homozygous hemoglobin c disease. autopsy revealed vegetations on the aortic valve, especially on the left coronary cusp. there was anomalous origin of the coronary arteries from the left sinus of valsalva. the large vegetation on the left coronary cusp had extended into the left main-stem coronary artery and obstructed it. there wa ...19883415444
recent trend of chemotherapy for infective endocarditis in japan.out of the 10 patients with infective endocarditis (ie) at kawasaki municipal hospital, 8 had ie due to streptococcus viridans. out of 8 patients with streptococcus ie, 6 were successfully treated with benzyl penicillin alone or in combination with kanamycin. one patient was cured with cephaloridine. two hundred and thirty ie patients admitted to hospitals at kantou district were also studied. ninety nine of 116 patients with streptococcus viridans ie were successfully treated with potentially a ...19854021065
infective endocarditis in children.the clinical manifestations, infective microorganisms, underlying diseases, complications and prognosis of infective endocarditis (ie) were studied in 17 current patients. data were compared with 101 previous cases reported in japan. most patients with ie (110/118 = 93.2%) had underlying heart diseases. ie was noted most often in patients with ventricular septal defect (vsd) and tetralogy of fallot. the incidence of post operative endocarditis was high (29.4% in the present series and 9.0% in th ...19854021067
extracranial mycotic aneurysms in infective endocarditis.nine of 217 (4.15%) patients with infective endocarditis who were followed from october 1978 to february 1984 had extracranial mycotic aneurysms (ma). age range of patients was 6-43 years (mean of 24.8 years) and 7 were male. etiologic agents were streptococcus viridans (3 cases), staphylococcus aureus (2 cases), staphylococcus epidermidis (1 case), and pseudomonas aeruginosa (1 case). two patients had negative blood cultures. the ma involved the arteries of the limbs (5 cases), thoracic (3 case ...19863512135
septic arthritis due to aerococcus viridans.a 20-year-old woman was found to have septic arthritis of the hip due to aerococcus viridans. this organism closely resembles streptococcus viridans, but forms gram positive tetrads rather than chains in broth media. the organism has been reported rarely to cause endocarditis and one case of osteomyelitis has been observed. to our knowledge septic arthritis due to aerococcus viridans has not been previously reported.19854087248
infective endocarditis in swedish children. i. incidence, etiology, underlying factors and port of entry of infection.a retrospective study of swedish children with infective endocarditis (ie) during the period 1971-80 was made. sixty-six instances were identified in 64 children (0.39 cases per 100,000 children per year). fifty (78%) had a previously known heart disease. most commonly this was a ventricular septal defect and tetralogy of fallot. seventy-one percent had positive blood cultures. streptococcus viridans and staphylococcus aureus were most commonly isolated. twenty-two percent of the children had un ...19863564983
dental status and recurrence of streptococcus viridans endocarditis. 19714103077
should good teeth be extracted to prevent streptococcus viridans endocarditis? 19714103078
teeth and streptococcus viridans endocarditis. 19714103409
successful two-week treatment schedule for penicillin-susceptible streptococcus viridans endocarditis. 19714108262
factors influencing mortality from infective endocarditis in two district general hospitals.factors influencing mortality were studied in 92 consecutive cases of infective endocarditis admitted to two district general hospitals between january 1975 and april 1982. thirty two patients died, an overall mortality of 35%, 13 patients died before diagnosis and 19 despite aggressive antimicrobial therapy. bactericidal antibiotic levels were monitored in 39 cases but these did not appear to influence outcome. mortality was lowest for streptococcus viridans infection (15%) but rose to 50% for ...19873671266
left atrial myxoma infected with streptococcus viridans.a case is described of streptococcus viridans endocarditis involving a left atrial myxoma. the diagnosis was made by echocardiography and the infected tumour was successfully treated by surgical removal. a review of the published literature about left atrial myxomas underlines the importance of performing echocardiography in all patients with suspected endocarditis.19883068157
immunocompromised animal models for the study of antibiotic combinations.studies of various models of pseudomonas aeruginosa infections in neutropenic animals have demonstrated the superiority of the combination of beta-lactam and aminoglycoside antibiotics when compared with a single drug alone. a limited number of studies carried out in models of klebsiella pneumoniae infections in neutropenic animals have shown similar results. the efficacy of double beta-lactam combinations for the treatment of gram-negative bacillary infections has not been studied as extensivel ...19863087166
post-mortem bacterial culture of bronchial mucus and heart blood in hospital and non-hospital autopsies: effect of morgue time and length of hospitalization.we studied cultures of 109 bronchial mucus and 67 heart blood specimens from unselected hospital autopsies and 40 bronchial mucus and heart blood specimens from unselected non-hospital (forensic) autopsies, performed 1-11 days after death. the most prevalent bacterium was streptococcus viridans. no association was found between morgue time and the number of species isolated from each bronchial mucus or heart blood specimen in either hospital or non-hospital autopsies, nor between morgue time and ...19863096018
preterm labor: stimulation of arachidonic acid metabolism in human amnion cells by bacterial products.there is a strong association between preterm labor and infection. some potentially pathogenic bacteria have phospholipase activity, and it has been suggested that release of phospholipase from these organisms may increase prostaglandin e2 synthesis in amnion cells and hence initiate preterm labor. in this study we established monolayer amnion cell cultures from tissue collected at elective cesarean section at term before labor. cells were prelabeled with tritiated arachidonic acid and then furt ...19873103451
microbiological and pharmacological behavior of 7-chlorolincomycin.replacement of the 7-(r) hydroxyl group of lincomycin by a 7-chloro-substituent produced a compound with greater in vitro activity than the parent. laboratory studies of this compound showed it to be highly active against all of the following strains of gram-positive organisms examined, including penicillinase- and nonpenicillinase-producing staphylococci, diplococcus pneumoniae, streptococcus viridans and streptococcus pyogenes. the enterococci, as well as all the gram-negative organisms tested ...19694389137
[study of the biological properties of streptococcus viridans isolated from healthy persons and from chronic tonsillitis patients]. 19744418989
in vitro activity of ro 15-8074 and ro 19-5247.the in vitro activity of ro 15-8074 (cefetamet) and ro 19-5247, new oral cephalosporins, was compared with that of amoxicillin, cephalexin, cefaclor, cefuroxime and erythromycin against 292 clinical isolates using the agar dilution method. both ro 15-8074 and ro 19-5247 were very active against proteus mirabilis, neisseria gonorrhoeae, haemophilus influenzae and streptococcus pyogenes, but less active against staphylococcus saprophyticus and enterobacter cloacae. ro 19-5247 was more active than ...19873109897
propionibacteria isolates and asymptomatic infections of the peritoneal effluent in capd patients.during the past two years our laboratory has isolated propionibacterium-an anaerobic gram-positive rod-on 40 occasions from the drainage fluid of 25 patients on capd and eight on ipd. most patients had no symptoms and the fluid was sent for culture after treatment of peritonitis, during training period, and occasionally because it was cloudy. no association was found with patients' age, length on dialysis, or previous peritonitis episodes. the only statistically significant association (p = 0.03 ...19863110672
[serological study on streptococcus viridans isolated from the oral cavity (author's transl)]. 19734524125
isolation of protoplasts from the blood in a case of streptococcus viridans cholangitis. 19724653134
[surgical aortic valve replacement for acute streptococcus viridans endocarditis with simultaneous moderate hemophilia a].this is a report of a 25-year-old patient with known aortic valve stenosis since early youth and hemophilia a, showing recurrent joint bleeding. acute streptococcus endocarditis induced aortic valve insufficiency resulting in cardiac failure. aortic valve replacement was performed after substitution of factor viii, during which intra- and postoperative bleeding was prolonged by pericardial adhesions. heparin was administered during cardiopulmonary-bypass as usual, but usual postoperative cumarin ...19883145652
streptococcus viridans endocarditis: favorable prognosis in geriatric patients. prognosis depends on correct identification of the organism and appropriate antibiotic therapy. 19734710893
successful resuscitation in coronary embolism occurring as a complication of bacterial endocarditis caused by cell wall defective streptococcus viridans. 19734753841
multiple brain abscesses secondary to dental caries and severe periodontal disease.a case is reported in which an intra-oral focus of sepsis is thought to have resulted in the patient developing multiple brain abscesses without the presence of lung infection or cardiac valvular disease. the link between the two sites of infection is supported by the isolation of two streptococcus viridans species normally associated with dental caries and periodontal disease. the management of multiple brain abscesses is discussed.19883165021
management of catheter-related infections in pediatric patients.broviac catheters are commonly used to provide parenteral nutrition and access for infusion of blood products and drugs to pediatric patients. sepsis is the most common serious complication of continued catheter use. although removal of the catheter is generally recommended when it becomes contaminated, it may not be feasible to do so without compromising patient care. we evaluated the management of catheter-related infections in pediatric patients with and without removal of catheter. seventy-s ...19883278159
studies on bacteriocinogeny of streptococcus strains. i. bacteriocinogeny of strains of the streptococcus viridans group. 19714933384
immunofluorescence studies of cardiac valves in infective endocarditis.mitral and aortic valves removed at emergency cardiac surgery from a patient with infective endocarditis caused by streptococcus viridans were studied by immunofluorescence to ascertain the extent and pattern of various immune reactants within the large valvular vegetations. heavy intravalvular deposits of igg as well as bacterial antigen were present. much more focal interstitial igm and c3 deposits were noted within vegetations and valve substance. diffuse endocardial and subendocardial deposi ...19853883933
[neonatal meningitis caused by streptococcus mitis].we report on a female newborn, 37 weeks of gestational age, who - after normal pregnancy and delivery - fell ill with a neonatal meningitis caused by streptococcus mitis. until now this bacillus has been thought to be apathogen. the disease was cured completely by penicillin therapy. the infection of a healthy newborn caused by streptococcus mitis, a streptococcus viridans, has not been described before.19853908918
peritonitis due to streptococcus viridans in patients receiving continuous ambulatory peritoneal dialysis. 19853919872
penicillin allergy and desensitization in serious infections during pregnancy.penicillin allergy presents a major obstacle to the successful management of some antepartum infections. we studied 15 pregnant women with histories of penicillin allergy confirmed by positive immediate wheal-and-flare skin tests. thirteen had syphilis, one listeria sepsis, and one streptococcus viridans endocarditis. each patient was desensitized over four to six hours by oral administration of increasing doses of penicillin v. at the completion of the procedure, full-dose parenteral therapy wi ...19853921835
[prevention of bacterial endocarditis].prevention of bacterial endocarditis is aimed at limiting the frequency, size, and duration of transient bacteremia with subsequent bacterial implantation on valvular endothelium in patients with cardiopathy. any procedure involving mucosa rich in normal flora or an infectious site can result in bacteremia, which can be minimized by selecting diagnostic and therapeutic procedures which are least traumatic. in addition, proper antibiotic prophylaxis should be administered according to the most fr ...19853977268
[biocenotic relationship between hemolytic streptococcus and streptococcus viridans in rheumatism and acute streptococcal infections]. 19715091498
septic arthritis of the acromioclavicular joint.a patient with isolated pyogenous arthritis of the acromioclavicular joint (a-c joint) caused by streptococcus viridans is described. the patient had no underlying disease. minor trauma preceded shortly the development of the septic process. the patient was treated successfully with surgical drainage and antibiotics. to our knowledge this is the first case report of septic arthritis of the a-c joint caused by streptococcus viridans. the a-c joint is rarely involved in septic processes. even cond ...19854015350
teeth, streptococcus viridans and subacute bacterial endocarditis. 19695260566
[plaque flora and dental caries. 3. biochemical activity of streptococcus viridans and serological group k. from the dental plaque of caries-free and caries-active persons]. 19705275060
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