| structural and functional characterization of peptides derived from the carboxy-terminal region of a defensin from the tick ornithodoros savignyi. | tick defensins may serve as templates for the development of multifunctional peptides. the purpose of this study was to evaluate shorter peptides derived from tick defensin isoform 2 (osdef2) in terms of their antibacterial, antioxidant, and cytotoxic activities. we compared the structural and functional properties of a synthetic peptide derived from the carboxy-terminal of the parent peptide (os) to that of an analogue in which the three cysteine residues were omitted (os-c). here, we report th ... | 2013 | 23553969 |
| anti-inflammatory and anti-endotoxin properties of peptides derived from the carboxy-terminal region of a defensin from the tick ornithodoros savignyi. | antimicrobial peptides are small cationic peptides that possess a large spectrum of bioactivities, including antimicrobial, anti-inflammatory and antioxidant activities. several antimicrobial peptides are known to inhibit lipopolysaccharide (lps)-induced inflammation in vitro and to protect animals from sepsis. in this study, the cellular anti-inflammatory and anti-endotoxin activities of os and os-c, peptides derived from the carboxy-terminal of a tick defensin, were investigated. both os and o ... | 2016 | 26662999 |
| distribution of endemic and introduced tick species in free state province, south africa. | the distributions of endemic tick vector species as well as the presence of species not endemic to free state province, south africa, were determined during surveys or opportunistic collections from livestock, wildlife and vegetation. amongst endemic ticks, the presence of rhipicephalus appendiculatus was confirmed in the north of the province, whilst rhipicephalus decoloratus was collected at 31 localities mostly in the centre and east, and ixodes rubicundus at 11 localities in the south, south ... | 2015 | 26244582 |
| molecular phylogeny of soft ticks (ixodida: argasidae) inferred from mitochondrial genome and nuclear rrna sequences. | the genus-level classification of soft ticks (argasidae) is controversial. a previous phylogenetic analysis of morphological and developmental characters found that the genus ornithodoros was paraphyletic and raised a new genus, carios, for species previously in the genera antricola, argas, ornithodoros, and nothoaspis (klompen and oliver, 1993). genetic analyses of soft ticks to date have been limited to 16s rrna, which is not highly phylogenetically informative for this group. we sequenced the ... | 2014 | 24378079 |
| morphological and molecular description of immature stages of ornithodoros savignyi (acari: argasidae). | this study was designed to provide more details about larva, first nymph, and second nymph of ornithodoros savignyi using a combination of light microscopy (lm), scanning electron microscopy (sem), and partial sequence of mitochondrial 16s ribosomal ribonucleic acid (rrna). the main characteristics of larva are wrinkled integument with many grooves, gnathosoma without camerostome cheeks, hypostome with a pair of large teeth apically, and tarsus without humps. the comparisons between the first an ... | 2016 | 27117161 |