| anti‑inflammatory and antioxidant activity of the traditional herbal formula gwakhyangjeonggi‑san via enhancement of heme oxygenase‑1 expression in raw264.7 macrophages. | gwakhyangjeonggi‑san (ghjgs) is a mixture of herbal plants, including agastache rugosa, perilla frutescens, angelica dahurica, areca catechu, poria cocos, magnolia officinalis, atractylodes macrocephala, citrus reticulata, pinellia ternata, platycodon grandiflorum, glycyrrhiza uralensis, ziziphus jujuba and zingiber officinale. ghjgs has been used for treating diarrhea‑predominant irritable bowel syndrome in traditional korean medicine. in the present study, the anti‑inflammatory and antioxidant ... | 2016 | 27052497 |
| pesticide residue monitoring in korean agricultural products, 2003-05. | between 2003 and 2005, a total of 11,716 samples were collected and analysed to determine the level of pesticides residues. multi-residue methods (mrms) capable of simultaneously determining 250 pesticides were used. of the 11,716 samples, 89.1% had no detectable residues and 1.7% had violative residues. the detection rates by commodity group were 11.4, 8.6, 0.3, and 0.02% for vegetables, fruit, grain, mushrooms, and the others, respectively. agricultural products with pesticide residues were pe ... | 2009 | 24784964 |
| biological evaluation of isoegomaketone isolated from perilla frutescens and its synthetic derivatives as anti-inflammatory agents. | the anti-inflammatory activities of a prepared isoegomaketone 3a and its derivatives 3b-3f were evaluated in raw 264.7 cells. among these, the compound 3d was displayed the most potent inhibitory activities against production of nitric oxide, monocyte chemoattractant protein-1 and interleukin-6. based on these results, the abilities of compounds 3a-3f to modulate nf-κb and ap-1-mediated gene transcription using a luciferase reporter assay were investigated. the transcriptional activities of nf-κ ... | 2011 | 21910048 |
| health effects of omega-3,6,9 fatty acids: perilla frutescens is a good example of plant oils. | perilla frutescens seeds are a good source of polyunsaturated fatty acids (pufas). the seeds of perilla are small end globular weight about 4 g/1000, contained approximately 35-45% oil. however the leaves are a very poor source of oil, since they contain only 0.2%. in addition, only the seed oil contains the omega 3 fatty acid alpha-linolenic acid (ala). in comparing to other plant oils, perilla seed oil consistently contains the one of the highest proportion of omega-3 (ala) fatty acids, at 54- ... | 2011 | 21909287 |
| [comparative analysis of volatile components of medicinal materials from perilla frutescens]. | to analyze the differences of volatile components of medicinal materials from perilla frutescens (perillae folium; perillae caulis; perillae fructus). | 2012 | 23705362 |
| natural products: perspectives in the pharmacological treatment of gastrointestinal anisakiasis. | to evaluate the activity of different natural products against l3 larvae of anisakis type i. | 2015 | 26321513 |
| calcium and oxidative stress mediate perillaldehyde-induced apoptosis in candida albicans. | new anti-candida albicans drugs are needed due to the emergence of resistant cases in recent years. perillaldehyde (pae) is a natural monoterpenoid compound derived from perilla frutescens. the minimum inhibitory concentration of pae against c. albicans was 0.4 μl/ml. we aimed to elucidate the antifungal mode of action of pae against c. albicans. the antifungal activity of pae against c. albicans was found to correlate with an elevation in intracellular ca(2+) and accumulation of ros. several do ... | 2017 | 28224196 |
| molecular cloning and characterization of a perilla frutescens cytochrome p450 enzyme that catalyzes the later steps of perillaldehyde biosynthesis. | perilla produces the cyclohexanoid monoterpene perillaldehyde as a major constituent of an essential oil that is accumulated in its glandular trichomes. perillaldehyde is a marker compound for quality control of soyo and has biological activities such as antibacterial, sedative, or vasodilatory effects. the predicted perillaldehyde formation involves the cyclization of geranyl diphosphate, hydroxylation, and oxidation, and cytochrome p450 plays a crucial role in perillaldehyde biosynthesis. in t ... | 2017 | 27890582 |
| functional identification of oleate 12-desaturase and ω-3 fatty acid desaturase genes from perilla frutescens var. frutescens. | we described identification, expression, subcellular localization, and functions of genes that encode fatty acid desaturase enzymes in perilla frutescens var. frutescens. perilla (perilla frutescens var. frutescens) seeds contain approximately 40 % of oil, of which α-linolenic acid (18:3) comprise more than 60 % in seed oil and 56 % of total fatty acids (fas) in leaf, respectively. in perilla, endoplasmic reticulum (er)-localized and chloroplast-localized ω-3 fa desaturase genes (pfrfad3 and pfr ... | 2016 | 27637203 |
| capturing of the monoterpene olefin limonene produced in saccharomyces cerevisiae. | monoterpene olefins such as limonene are plant compounds with applications as flavouring and fragrance agents, as solvents and potentially also in polymer and fuel chemistry. we engineered baker's yeast saccharomyces cerevisiae to express a (-)-limonene synthase from perilla frutescens and a (+)-limonene synthase from citrus limon. both proteins were expressed either with their native plastid targeting signal or in a truncated form in which the plastidial sorting signal was removed. the yeast ho ... | 2015 | 25164098 |
| pollination effects on antioxidant content of perilla frutescens seeds analysed by nmr spectroscopy. | the effects of perilla frutescens pollination on the content of seed antioxidants were analysed by agronomical and pollination trials, comparing seeds produced from bagged plants in 2013 (a) to prevent access to pollinating insects, and seeds from open-pollinated plants in 2013 (b) and 2015 (c). the seeds of open-pollinated plants were significantly more numerous and heavier than those of self-pollinated plants. (1)h nmr seed analysis showed a higher presence of phenolic compounds in open-pollin ... | 2017 | 28278651 |
| perilla frutescens (l.) britton: honeybee forage and preliminary results on the metabolic profiling by nmr spectroscopy. | nuclear magnetic resonance (nmr) spectroscopy has emerged as a technology for metabolite characterisation of both foods and plants. nmr technique allows to analyse metabolite content in a single experiment, in a non-destructive way and with a very simple sample preparation. this study characterises the metabolites of perilla frutescens var. crispa leaf and flower for the first time by nmr. our results showed higher metabolite content in leaves compared to flowers, highlighting the presence of am ... | 2013 | 23240606 |
| stress-induced flowering. | many plant species can be induced to flower by responding to stress factors. the short-day plants pharbitis nil and perilla frutescens var. crispa flower under long days in response to the stress of poor nutrition or low-intensity light. grafting experiments using two varieties of p. nil revealed that a transmissible flowering stimulus is involved in stress-induced flowering. the p. nil and p. frutescens plants that were induced to flower by stress reached anthesis, fruited and produced seeds. t ... | 2010 | 20505356 |
| characteristics of high alpha-linolenic acid accumulation in seed oils. | modern diets are often deficient in omega-3 fatty acids and additional dietary sources of omega-3 fatty acids are useful. in order to investigate the molecular basis of the high accumulation of the omega-3 fatty acid, alpha-linolenic acid (18:3), in three different plants, flax (linum usitatissimum), dracocephalum moldavica, and perilla frutescens omega-3 desaturase activity, transcript levels, and 18:3 in-vivo synthesis were examined. the 18:3 content was found to be higher at the later develop ... | 2008 | 18597133 |
| [effects of celosia argentea and cucurbita moschata extracts on anti-dnp ige antibody production in mice]. | we have already reported that the perilla frutescens extract (pfe) suppressed anti-dna ige antibody production in mice. in this study, we prepared extracts of celosia argentea l. (cae) and cucurbita moschata duch (cme), which are chinese herbal medicines like perilla frutescens, and examined the effects on anti-dnp antibody responses in mice. to examine the effects of cae & cme on primary antibody responses, cae & cme were intraperitoneally injected the day before primary immunization of dnp-ova ... | 1994 | 8031259 |
| a flavanone derivative from the asian medicinal herb (perilla frutescens) potently suppresses ige-mediated immediate hypersensitivity reactions. | perilla frutescens is a dietary leafy herb consumed as a traditional japanese condiment as well as used for chinese medicine with anti-inflammatory activity. here we report a hitherto-unrecognized p. frutescens phytochemical that potently suppresses ige-mediated type i hypersensitivity reactions. structural analysis reveals that the purified anti-allergic compound (perilla-derived methoxyflavanone, pdmf) is identified as 8-hydroxy-5,7-dimethoxyflavanone. pdmf significantly inhibits ige-mediated ... | 2017 | 27986566 |
| nocardioides perillae sp. nov., isolated from surface-sterilized roots of perilla frutescens. | a gram-stain-positive, rod-shaped actinobacterium, designated strain i10a-01402(t), was isolated from surface-sterilized roots of a medicinal plant, perilla frutescens, collected in a suburb of beijing, china. chemotaxonomically, the strain contained ll-diaminopimelic acid as the diagnostic diamino acid and mk-8(h4) as the predominant menaquinone. the phospholipids were diphosphatidylglycerol, phosphatidylglycerol and phosphatidylinositol. the major fatty acids were c17 : 1ω9c, c18 : 1ω9c, c17 : ... | 2013 | 22707530 |
| separation and measurement of direct and indirect effects of light on stomata. | conductance for water vapor, assimilation of co(2), and intercellular co(2) concentration of leaves of five species were determined at various irradiances and ambient co(2) concentrations. conductance and assimilation were then plotted as functions of irradiance and intercellular co(2) concentration. the slopes of these curves allowed us to estimate infinitesimal changes in conductance (and assimilation) that occurred when irradiance changed and intercellular co(2) concentration was constant, an ... | 1981 | 16661884 |
| [inhibition of antigen-specific t helper type 2 responses by perilla frutescens extract]. | perilla frutescens leaf extract (pfe) is known as a natural medicine with anti-allergic activities, although its mechanism of action remains unclear. in this study, we examined the effect of pfe on antigen-specific antibody and on cytokine production. mice were immunized three times (weekly) with sugi basic protein (sbp), a major allergen of japanese cedar pollen, in alum adjuvant. pfe was injected intraperitoneally into mice on day 2 before and on the day of each immunization with sbp in alum a ... | 1999 | 10355148 |
| monoterpene engineering in a woody plant eucalyptus camaldulensis using a limonene synthase cdna. | metabolic engineering aimed at monoterpene production has become an intensive research topic in recent years, although most studies have been limited to herbal plants including model plants such as arabidopsis. the genus eucalyptus includes commercially important woody plants in terms of essential oil production and the pulp industry. this study attempted to modify the production of monoterpenes, which are major components of eucalyptus essential oil, by introducing two expression constructs con ... | 2010 | 20055958 |