Publications

TitleAbstractYear
Filter
PMID
Filter
genetic variation in tula hantaviruses: sequence analysis of the s and m segments of strains from central europe.hantavirus carried by the european common vole microtus arvalis from moravia (czech republic) was analyzed by rt-pcr-sequencing and by reactivity with a panel of monoclonal antibodies (mabs). sequencing of the full-length s segment and the proximal part of the m segment showed that the virus belonged to genotype tula (tul) we discovered earlier in microtus arvalis from central russia. this finding supported the concept of host dependence of hantaviruses. phylogenetic analyses suggested a similar ...19958837887
reservoir competence of the vole, clethrionomys rufocanus bedfordiae, for borrelia garinii or borrelia afzelii.in autumn of 1994 and spring of 1995, we examined borrelia infection among microtinae voles, clethrionomys rufocanus bedfordiae, in hokkaido, japan. in bsk culturing of the earlobe tissues of 45 c. rufocanus bedfordiae captured, twelve rodents were positive for borrelia. eight isolates were used for the polymerase chain reaction (pcr) and the restriction fragment length polymorphism (rflp) analysis. according to the results, these isolates were classified into b. garinii or b. afzelii. it is con ...19968871531
characterization of tula virus antigenic determinants defined by monoclonal antibodies raised against baculovirus-expressed nucleocapsid protein.tula virus was recently discovered by rt-pcr in lung samples from european common voles (microtus arvalis and m. rossiaemeridionalis). since virus isolation attempts had been unsuccessful, no antigen was available for analysis or for use in immunoassays. to circumvent this, complete tula virus nucleocapsid protein (bac-tul-n) was expressed in recombinant baculovirus. rodent antibody end-point titers to bac-tul-n and to truncated n fragments indicated that the nh2-terminal region is the major ant ...19968896239
virulence of ppst+ and ppst- strains of yersinia pestis for guinea-pigs.guinea-pigs were infected subcutaneously or by respiratory challenge with plasmid-containing (ppst+pcad+pfra+) yersinia pestis strain 358 and its ppst-pcad+pfra+, ppst+pcad+pfra- and ppst-pcad+pfra- derivatives, grown in vitro at 28 degrees c or at 37 degrees c. lack of plasmid ppst did not lead to an increase in ld50 with either route of challenge. when the virulence of the four y. pestis strains grown at the two temperatures was compared, the ld50 values of those grown at 37 degrees c were low ...19968958247
quasispecies in wild-type tula hantavirus populations.tula virus (tul) is a recently detected hantavirus carried by european common voles. reverse transcriptase pcr cloning was used to study tul s segment/n protein quasispecies. both the distribution and character of mutations observed in three mutant spectra indicated limited selection at the protein level. at least 8% of the mutations were neutral or well tolerated; fixation of such mutations may play a role in tul evolution in its natural host.19968971044
isolation and characterization of tula virus, a distinct serotype in the genus hantavirus, family bunyaviridae.a vero e6 cell culture isolate of tula virus (tul), a hantavirus first detected in european common voles (microtus arvalis and m. rossiaemeridionalis) by rt-pcr was obtained after initial passaging of tul-infected vole lung samples in laboratory-colonized m. arvalis. tul was defined as a classical serotype by a cross-focus-reduction neutralization test (frnt) and was also shown to be distinct from other hantaviruses by haemagglutination inhibition assay. the sequences of s, m and partial l genom ...19969000098
safety study of the sag2 rabies virus mutant in several non-target species with a view to its future use for the immunization of foxes in europe.the safety of the sag2 virus, a low virulence mutant of the sad strain, was investigated in ten species of mammals and seven species of birds liable to consume vaccine baits. these species are the western hedgehog (erinaceus europaeus), the meadow vole (microtus arvalis), the bank vole (clethrionomys glareolus), the water vole (arvicola terrestris), the field mouse (apodemus flavicollis or a. sylvaticus), the norway rat (rattus norvegicus), the european badger (meles meles), the domestic ferret ...19969014291
[leptospira antibodies in small mammals in eastern slovakia].during the five years (1991-1995) mostly free living small mammals were examined serologically for the presence of antibodies to leptospira. serological examinations were used by kmety and bakoss (1978). altogether, 2493 individuals of 22 species were examined, an important part of host material (69.6%) was caught in two lowland areas which are intensively cultivated landscapes (east slovakian lowland and kosická kotlina basin). the remaining material comes from submontane areas with less agricu ...19969045500
[further study of hantavirus circulation in the russian federation].lung specimens of 1514 small mammals of 35 species captured in 1991-1995 at 9 territories of russia were tested in elisa for virus antigens of hemorrhagic fever with the renal syndrome (hfrs). the antigens were detected in lung specimens of clethrionomys glareolus, microtus arvalis, microtus gregalis, microtus fortis, arvicola terrestris, apodemus agrarius, micromys minutus, and sorex sp., well known as hantavirus reservoirs, captured in the vologda, yaroslavl, saratov, astrakhan, and chita regi ...19979182404
novel strategies for eutherian x marsupial somatic cell hybrids: mapping the genome of monodelphis domestica.two hundred thirty-seven independent somatic cell hybrids have been obtained between opossum (monodelphis domestica) splenocytes, bone marrow cells, or primary fibroblasts, and hprt-deficient or tk-deficient chinese hamster, mouse, american mink, or common vole fibroblast lines. because extreme segregation and fragmentation of marsupial chromosomes commonly occurs in eutherian x marsupial somatic cells hybrids, we developed a rapid primary screening method that enables the identification of prim ...19979186503
investigations of pneumocystosis among humans and rodents in lithuania.pneumocystosis (pneumocystis carinii pneumonia) is a parasitic disease which in lithuania used to be diagnosed only with the use of pathohistological methods. the aim of our study was to determine prevalence of p. carinii antibodies among children and women, using immunochemical method (elisa) and to find out which groups of patients have higher antibody titres. we also addressed the question of infection with p. carinii among rodents. after investigating 9 species of rodents it was found that m ...19979259608
puumala virus and two genetic variants of tula virus are present in austrian rodents.puumala and tula viruses are hantaviruses found in europe and are associated with the rodents clethrionomys glareolus and microtus arvalis, respectively. puumala virus is associated with the human disease nephropathia epidemica. in austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by puumala virus infection, have been reported but not virologically confirmed [leschinskaya et al., 1991; aberle et al., 1996]. to identify the hantaviruses that are present in austr ...19979334930
[the isolability of the causative agent of pseudotuberculosis from rodents in georgia].since 1960 the cases of isolating the pseudopathogen agent have been recorded in georgia at particular regular intervals. the accumulated material mainly involves epizootiological findings, which may provide a definite insight into the prevalence of this disease in georgia. in 1960-1990, 31 strains were isolated in particular regions and populated areas; these included 17 strains from grey rats, 4 from house mice, 9 from common voles, and 1 from field mice. the particular constancy of isolation ...19979445999
[relation between characteristics of the small mammal population and occurrence of leptospira antibodies].five rodent species (apodemus flavicollis, a. agrarius, a. microps, clethrionomys glareolus and microtus arvalis) were examined serologically for presence of antibodies to leptospira. small mammals were caught in several areas of eastern slovakia, an important part of host material coming from east slovakian lowland (45.7%), south part of kosice basin (26.5%) and slovak carst (10.1%). serological examinations were used by kmety and bakoss (1978), the sexual condition of rodents were ascertained ...19979481926
infectivity of cryptosporidium muris isolated from cattle.the infectivity of a bovine isolate of cryptosporidium muris for various animals was studied by transmission experiments. neonatal balb/c mice, adult balb/c mice, scid mice, common voles (microtus arvalis), bank voles (clethrionomys glareolus), common field mice (apodemus sylvaticus), mongolian gerbils (meriones unguiculatus), desert gerbils (gerbilus gerbilus), guinea pigs, rats, rabbits and goats were used to test the infectivity of this isolate. among these host species, only mongolian gerbil ...19989615952
concurrent decrease of vasopressin and protein kinase calpha immunoreactivity during the light phase in the vole suprachiasmatic nucleus.vasopressin (avp) is a major neuropeptide in the suprachiasmatic nucleus, the mammalian hypothalamic circadian pacemaker. protein kinase calpha is a putatively coupled intracellular messenger. mean numbers of avp- and protein kinase calpha-immunoreactive neurons were determined in the suprachiasmatic nucleus of common voles, entrained to a 12:12 h light-dark (ld) cycle, at the beginning of the light period (zeitgeber time zero) and 6 h later (zeitgeber time six). at zeitgeber time zero, mean num ...19989654347
recombination in tula hantavirus evolution: analysis of genetic lineages from slovakia.to examine the evolution of tula hantavirus (tul), carried by the european common vole (microtus arvalis and m. rossiaemeridionalis), we have analyzed genetic variants from slovakia, the country where the virus is endemic. phylogenetic analysis (phylip) based on either partial (nucleotides [nt] 441 to 898) or complete n-protein-encoding sequences divided slovakian tul variants into two main lineages: (i) strains from eastern slovakia, which clustered with russian strains, and (ii) strains from w ...19999847372
selective isolation of pseudomonas stutzeri from vertebrate faeces on rambach agar.faecal samples collected from 308 wild birds of 25 species and 19 rodents of 3 species in south moravia (czechland) were pre-incubated in müller-kauffmann tetrathionate broth at 42 degrees c for 24 h and then streaked onto rambach agar plates which were incubated at 37 degrees c for 48 h. seventeen out of 22 isolates forming orange-red colonies on rambach agar were identified as pseudomonas stutzeri, the rest as pseudomonas sp. and alcaligenes sp. the colonies of p. stutzeri were either dry, wri ...19989861678
lack of circadian patterns in vasoactive intestinal polypeptide release and variability in vasopressin release in vole suprachiasmatic nuclei in vitro.organotypic hypothalamic cultures of neonatal rats comprising the suprachiasmatic nuclei (scn) produce stable 20 h release patterns of vasoactive intestinal polypeptide (vip) and arginine-vasopressin (avp). compared with rats, voles show variably expressed circadian activity patterns. in this study we measured neuropeptidergic release patterns in organotypic scn cultures of neonatal common voles (microtus arvalis, n = 6). slices were prepared at postnatal day 6. after 14 days of incubation, 2 h ...199910025569
[dogs recognize distinctive chromosomal forms of arvalis and obscurus common voles (microtus arvalis pallas, 1779) and individuals of the same type from diverse populations by smell]. 199910188099
[the ecology of the sibling species microtus arvalis pallas, 1779 and microtus rossiaemeridionalis ognev, 1924 (rodentia, cricetidae) in the tsimlianskie sands].ecological features and circadian activity of the common vole sibling species were studied upon joint and separate occurrences. both species had a similar abundance but different biotopical distribution. microtus arvalis--chromosome form "obscurus" populated the studied territory more uniformly the studied territory. m. rossiaemeridionalis tended to occur in humid coenoses. in case of joint occurrences, the sibling species occupied different regions of biotopes and the rhythms of their activity ...199910441910
aspects of mammalian spermatogenesis: electrophoretical analysis of protamines in mammalian species.protamines are small, highly basic proteins that replace histones and testicular basic proteins during the development of mature spermatozoa, spermatogenesis. in mammals, extensive disulfide crosslinking of protamines result in the formation of a compact chromatin structure devoid of transcriptional activity. as determined by isolation and electrophoresis of protamines, only one protamine has been detected in the mature spermatozoa of most mammalian species. however, in the spermatozoa of the mo ...199910597046
the suprachiasmatic nucleus in organotypic slice cultures of the common vole (microtus arvalis): comparison of development with rat and hamster and the effect of age.the intrinsic properties of the suprachiasmatic nucleus (scn), the site of the main circadian pacemaker in mammals, have recently been studied in vitro by means of organotypic slice culturing. so far, only neonatal rats and mice have been used for such developmental and functional analyses of the isolated pacemaker. here, the authors present a comparative developmental study of the scn of voles, rats, and hamsters in organotypic slice cultures. in contrast to strictly circadian organization of b ...200010677015
the vole species microtus arvalis and microtus rossiaemeridionalis in the urals: hybridization in the wild. 200010781329
genetic and morphological heterogeneity in small rodent whipworms in southwestern europe: characterization of trichuris muris and description of trichuris arvicolae n. sp. (nematoda: trichuridae).genetic and morphological variability of whipworms trichuris roederer, 1761 (nematoda: trichuridae), parasites of small rodents in southwestern europe, was studied. isozyme patterns of natural populations of nematodes parasitizing rodent species of the muridae (apodemus sylvaticus, apodemus flavicollis, mus musculus) and arvicolidae (clethrionomys glareolus, microtus agrestis, microtus arvalis) were analyzed at 6 putative loci. two diagnostic loci were found in t. muris from muridae and from arv ...200010864238
the effect of social environment on the immune response of female common voles in matriarchal laboratory groups.we used the hemagglutination test to investigate differences in the specific immune response to sheep red blood cells (srbc) of female common voles living in matriarchal groups. the applied test proved to be a useful tool for studying the effect of the social environment on the immune response in small mammals. the required blood sampling method did not affect reproductive traits. young female common voles showed a higher immune response than their mothers, which could have been caused by their ...200011150560
prevalence of igg antibodies response to borrelia burgdorferi s.l. in populations of wild rodents from mazury lakes district region of poland.three rodent species: clethrionomys glareolus, apodemus flavicollis and microtus arvalis from mazury lakes district of poland were examined for antibodies to borrelia burgdorferi by enzyme-labelled protein g assay (elga). c. glareolus had an exceptionally high prevalence of b. burgdorferi antibodies - 58%, but a. flavicollis and m. arvalis also showed significant prevalence of 16.6% and 10.5%, respectively. the elga method is highly specific with good reproducibility. nevertheless, some differen ...200011153035
[analysis of the incidence of tularemia in the breclav district 1994-1999].southern moravia is one of the areas where there are long-term natural foci of tularaemia. in 1994 in the breclav district an exacerbation of the disease was recorded in hares. during autumn hunts a positive reaction was recorded in 5.75% of examined hares. an elevated seropositivity persisted also in subsequent years and at the same time a higher human morbidity in the mentioned region. the objective of the investigation was to assess the causes and circumstances which led to the exacerbation o ...200111233673
experimental transmission of caryospora kutzeri (apicomplexa: eimeriidae) by rodent hosts.four laboratory-hatched european kestrels falco tinnunculus l. were fed on laboratory mice and common voles microtus arvalis pallas previously inoculated with different doses of sporulated oocysts of caryospora kutzeri böer, 1982. two kestrels that were fed infected mice shed c. kurtzeri oocysts 6 days after ingesting murine tissues. to compare direct and indirect transmissions, two of the kestrels were subsequently directly inoculated with 10(5) sporulated c. kutzeri oocysts and became patent o ...200111266130
findings of mycobacteria in insectivores and small rodents.the organs of 30 insectivorous mammals and 62 rodents from areas inhabited by people or livestock where cattle paratuberculosis or mycobacterial infections of swine had been found to occur were examined by cultivation during the monitoring of occurrence and spread of mycobacterioses in cattle and swine. mycobacteria were found in the organs of 3 insectivores (10%) and 6 rodents (9.7%). mycobacterium chelonae was isolated from the organs of the lesser white-toothed shrew (crocidura suaveolens) an ...200011271823
characterization of the genomic xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence.the xist locus plays a central role in the regulation of x chromosome inactivation in mammals, although its exact mode of action remains to be elucidated. evolutionary studies are important in identifying conserved genomic regions and defining their possible function. here we report cloning, sequence analysis, and detailed characterization of the xist gene from four closely related species of common vole (field mouse), microtus arvalis. our analysis reveals that there is overall conservation of ...200111337478
is high prevalence of echinococcus multilocularis in wild and domestic animals associated with disease incidence in humans?we investigated a focus of highly endemic echinococcus multilocularis infection to assess persistence of high endemicity in rural rodents, explore potential for parasite transmission to domestic carnivores, and assess (serologically) putative exposure versus infection frequency in inhabitants of the region. from spring 1993 to spring 1998, the prevalence of e. multilocularis in rodents was 9% to 39% for arvicola terrestris and 10% to 21% for microtus arvalis. from june 1996 to october 1997, 6 (7 ...200111384517
importance of surveillance of tularemia natural foci in the known endemic area of central europe, 1991-1997.marked activation of natural foci of tularemia in the known endemic area of central europe, comprising the borderland of slovakia, austria and the czech republic, led to an epidemic outbreak in western slovakia and an increase in the number of human tularemia cases in the adjoining regions of northeastern austria and southern moravia from 1995 to 1997. the aim of this paper was to present the results of a longitudinal study on the prevalence of infection with francisella tularensis in small mamm ...200111467089
a new geographical gradient in vole population dynamics.a new geographical gradient in the dynamics of small rodents is demonstrated by analysing 29 time series of density indices of the common vole (microtus arvalis) from poland, the czech republic and the slovak republic. this gradient extends from more stable northerly populations in coastal poland to more variable and cyclic populations in the southernmost parts of the slovak republic, and is hence a reversal of the fennoscandian gradient. all studied variables (such as mean density, cycle amplit ...200111487400
susceptibility of common voles to experimental toxoplasmosis.common voles (microtus arvalis) in groups of nine to 10 animals were inoculated per os with a dose of 1, 10, 1x10(2), 1x10(3), and of the k1 strain of toxoplasma gondii. all the common voles inoculated with 1 to 1 x 10(3) oocysts remained subclinical and survived. three of the 10 voles inoculated with 1 x 10(4) oocysts died between days 7 and 12 post inoculation (p.i.). antibodies were demonstrated in all the infected voles killed on day 60 p.i. the highest antibody titres in voles detected by t ...200111504242
[chromosomal and ontogenetic instability in sibling species of common vole (microtus arvalis group): comparative aspects].populations of chromosomal sibling species microtus arvalis and microtus rossiaemeridionalis were studied in ural region in habitats affected by high radiation and the control ones. frequency of chromosome disturbances in the marrow cells and fluctuating asymmetry (fa) of 8 craniometric characters were investigated. in impact populations the frequency of chromosome aberration was very high. such frequency was also maintained in the offspring of the first laboratory generation of m. arvalis. in n ...200111548401
[species specificity of karyotype instability under conditions of radionuclide contamination (the chernobyl nuclear power plant) in the voles, micrototus oeconomus, micrototus arvalis, and clethrionomys glareolus].the comparative analysis of frequencies of different type cytogenetic anomalies in voles microtus oeconomus, microtus arvalis, clethrionomys glareolus trapped in territories with different levels of radionuclide contamination inside the 30-km zone of estrangement around the chernobyl npp was carried out. animals with constitutive chromosome abnormalities were not revealed. the frequency of lympocytes with micronuclei was the most universal and sensitive character to chronic low-dose radiation in ...200111589050
tula hantavirus in belgium.european common voles (microtus arvalis), captured in belgium in 1999, were proven by molecular as well as by serological techniques to be infected with tula hantavirus (tulv). this is the first evidence for the presence of tulv in this country. no indication of spill-over infections of puumala virus, known to be highly endemic among bank voles (clethrionomys glareolus) within the same geographical regions as the trapped tulv-infected common voles, was observed. together with previous reports on ...200212002543
a comparative study of isolation-induced ultrasonic vocalization in rodent pups.the purpose of this study was to determine whether species differences in neonatal vocalizations of rodent pups could be observed. ultrasonic vocalizations of pups of 5 rodent species, mouse (icr), vole (microtus arvalis), syrian hamster, rat (wistar-imamichi), and mongolian gerbil were recorded from 3 to 15 or 21 days of age. recordings were made under conditions of separation from mothers and litter mates in a cooled chamber (approximately 10 degrees c). the major species differences observed ...200212012730
identification of tula hantavirus in pitymys subterraneus captured in the cacak region of serbia-yugoslavia.atypical serum neutralizing antibody responses to prototype strains of puumala viruses in some patients with hemorrhagic fever with renal syndrome (hfrs) have long suggested the existence of other hantaviruses in the balkans.200212044299
hybridocytochemical detection of mrna for calcitonin, cgrp, npy and somatostatin in thyroid parafollicular (c) cells in three rodent species.the present study was aimed at hybridocytochemical (hcc) detection and interspecies comparison of mrna for calcitonin (ct), calcitonin gene-related peptide (cgrp), neuropeptide y (npy) and somatostatin (ss) in thyroid c cells of two rodent families of wild microtidae: pine voles and common voles and also of laboratory muridae, wistar rats. studies were performed on adult males. the hcc method in situ and immunomax technique were used to detect mrna. dna oligonucleotide probes labeled with digoxi ...200212056636
utility of chromosomal position of heterochromatin as a biomarker of radiation-induced genetic damage: a study of chornobyl voles (microtus sp.).biomarkers that effectively document effects of chronic multi-generational exposure to contaminated environments on chromosomes would be valuable in risk assessment, remediation, and environmental decisions. native, free-ranging populations of voles inhabiting the highly radioactive regions surrounding reactor 4 of the chornobyl nuclear power station provide a model system to evaluate biological and chromosomal effects of chronic multi-generational exposure to radioactivity and other reactor mel ...200212092749
prevalence and abundance of cryptosporidium parvum and giardia spp. in wild rural rodents from the mazury lake district region of poland.prevalence and abundance of cryptosporodium parvum and giardia spp. were studied in 3 species of rodents from forests and abandoned agricultural fields in n.e. poland (clethrionomys glareolus n = 459; microtus arvalis n = 274; apodemus flavicollis n = 209). overall prevalence was consistently higher in the voles compared with a. flavicollis (70.6, 73.0 and 27.8% respectively for c. parvum and 93.9, 96.3 and 48.3% respectively for giardia spp.). prevalence and abundance of infection also varied m ...200212166517
chromatid gaps as a marker of mutagenic effect of environmental pollution in commensal and wild rodents of the ural mountains.it was supposed earlier that achromatic gaps could be used as markers of mutagenic effect of environmental pollution, especially under weaker clastogenic influences. the frequencies of true chromosome aberrations and those of chromatid gaps were estimated in house mice and common voles from uralian localities with various mutagenic potential of environment. gaps and breaks were distinguished according to the cbis system. in several localities, rodents displayed highly significant increase of the ...200212379012
prevalence of coinfection with francisella tularensis in reservoir animals of borrelia burgdorferi sensu lato.studies on lyme borreliosis and other tick-borne zoonoses in the austrian and slovakian borderland, a region endemic for tularemia, revealed a relatively high prevalence of infection with borrelia burgdorferi s.l. and francisella tularensis in small terrestrial mammals, as well as in the ticks, during a one-year survey. the occurrence of coinfection with the agents of lyme borreliosis and tularemia was assessed in different species of rodents.200212422587
distribution of hantavirus foci in belgium.during 1999 and 2000, we performed rodent captures on 15 sites all over belgium to evaluate the presence of hantaviruses in local rodent populations. viral antibody and rna detection was performed by elisa/focus reduction neutralisation test and rt-pcr, respectively. we found hantavirus-positive rodents on 13 out of 15 trapping sites and 3 rodent species were found positive for hantavirus infection. apart from puumala virus that was carried by clethrionomys glareolus, 2 additional rodent species ...200212443796
[chromosomal instability in rodents from the eurt territory: interspecies comparison].the common vole (microtus arvalis) and the mole vole (ellobius talpinus) were trapped in the eastern urals reserve (initial soil pollution 500-1000 ci/km2) where many dozens of generations came to pass after the 1957 accident in the plant "mayak" and in the middle and south urals and transurals localities with global level of the 90sr pollution. at present the average internal dose rate from 90sr was 0.413 mgy/day in m. arvalis and 0.985 mgy/day in e. talpinus. the total accumulated doses from e ...200212530146
[detection of hantavirus antigen in rodents in the czech republic].the work is based on the hitherto implemented examinations of lungs of rodents from the territory of the czech republic for the presence of hantavirus antigen. for detection of a species specific antigen the elisa set hantagnost from the poliomyelitis institute in moscow was used. a total of 1494 micromammalia of 15 species caught in 1991-2001 were examined. the hantavirus antigen was detected in the lungs of 101 individuals (6.8%) whereby representatives of the species microtus arvalis predomin ...200312647557
genetic evidence for tula virus in microtus arvalis and microtus agrestis populations in croatia.to determine the threat of hantavirus infection to u.s. forces, small mammals were sampled from training areas within croatia. of the 152 samples, 20 were positive for tula virus (tul), 12 common voles (microtus arvalis) and eight field voles (microtus agrestis). sequences from m. agrestis were found in five and sequences from m. arvalis were found in six of seven sequence groups. the high percentage of the same tul sequences in m. agrestis and m. arvalis suggests the co-occurrence of this virus ...200212656127
immunolocalization of pthrp in the sublingual glands of three mammals.the present study deals with immunohistochemical localization of pthrp in sublingual glands of white mouse, bank vole, and common vole. pthrp immunoreactivity was observed in epithelial cells of striated, interlobular and main excretory ducts of the salivary glands in all the three animal species tested. however, we found no positive reaction for pthrp in epithelial cells of the intercalated ducts. in striated duct cells, the reaction intensity was species-dependent. in bank vole and common vole ...200312705476
phylogeography of the common vole (microtus arvalis) with particular emphasis on the colonization of the orkney archipelago.to investigate the human introduction of the common vole microtus arvalis onto the orkney islands, the complete cytochrome b gene was sequenced in 41 specimens from both orkney (four localities) and elsewhere in their range (26 localities). orkney voles belonged to the same phylogenetic lineage, 'western', as individuals from france and spain indicating southwestern europe as the most likely source area for the islands. this result is of interest with respect to the movement and trading links of ...200312753214
[isolation of es-like lines of common voles of the genus microtus from blastocysts and germ cells and as a result of the fusion of somatic cells with mouse embryonic stem cells].three and four independent cell lines with limited pluripotency were obtained from the inner cell mass cells of blastocysts and primordial germ cells of common voles, respectively. the results of cytogenetic analysis suggest that all these lines originated from the embryos of f1 microtus rossiaemeridionalis x m. arvalis males and had a great number of near-triploid cells already during the early passages. the cells of these lines, like those of the inner cell mass, were characterized by the alka ...200312816050
echinococcus multilocularis: secondary poisoning of fox population during a vole outbreak reduces environmental contamination in a high endemicity area.this paper describes the role of fox population level on echinococcus multilocularis infection in foxes in a highly endemic area in eastern france. fox population level was monitored by spotlight survey at le souillot from 1989 to 2000, and from 1992 to 2000 at chemin, a control site located in a low endemic area. the infection level of the fox population was estimated at le souillot from winter 1995 to winter 1999 using a coproantigen elisa performed on faeces collected in the field. population ...200312906878
[the effects of adrenalectomy on the vas deferens of the castrated field mouse (microtus arvalis p.)]. 195212988411
[the development of the vas deferens in the field mouse (microtus arvalis p)]. 195212998154
[strains of acid fast bacilli isolated from microtus arvalis]. 195213002067
[studies on dissociation of the lublin 44 strain of mycobacterium tuberculosis isolated from microtus arvalis 1950]. 195413162247
[action of the adrenal cortex on the prostate in the field mouse (microtus arvalis p.); role of cortisone]. 195413192675
[study of the sexual biology of the field mouse (microtus arvalis p.)]. 195513303418
[normal sexual development of the field mouse (microtus arvalis p) from birth to the adult age]. 195613341000
[comparative studies on the reaction of albino laboratory mice & field mice (microtus arvalis pallas) to rabies virus infection]. 195713443436
[use of the field mouse (microtus arvalis) for type differentiation of mycobacteria tuberculosis]. 195713531321
[sensitivity of microtus arvalis and of certain arthropoda to influenza virus infection]. 196013732917
occurrence of renal and pulmonary syndrome in a region of northeast germany where tula hantavirus circulates.hantavirus species tula (tulv) is carried by european common voles (microtus spp.). its pathogenic potential for humans is unknown. in a rural region of northeast germany, a 43-year-old man became ill with fever, renal syndrome, and pneumonia. typing of late acute- and convalescent-phase sera by focus reduction neutralization assay revealed the presence of neutralizing antibodies against tulv. moreover, we detected tulv genetic material in microtus arvalis animals that were trapped at places onl ...200314532254
impact of herbivores on nitrogen cycling: contrasting effects of small and large species.herbivores are reported to slow down as well as enhance nutrient cycling in grasslands. these conflicting results may be explained by differences in herbivore type. in this study we focus on herbivore body size as a factor that causes differences in herbivore effects on n cycling. we used an exclosure set-up in a floodplain grassland grazed by cattle, rabbits and common voles, where we subsequently excluded cattle and rabbits. exclusion of cattle lead to an increase in vole numbers and a 1.5-fol ...200414566555
preliminary molecular characterization of cryptosporidium parvum isolates of wildlife rodents from poland.isolates of cryptosporidium were collected from 3 species of woodland and field rodents (clethrionomys glareolus, microtus arvalis, and apodemus flavicollis) and were characterized by polymerase chain reaction amplification and sequencing of fragments of the oocyst wall protein (cowp) gene and of the 18s ribosomal rna gene. sequence analysis of these markers revealed that the animals were infected with c. parvum, and that the genotype involved was almost identical to the mouse genotype previousl ...200314627156
milbemycin oxime in a new formulation, combined with praziquantel, does not reduce the efficacy of praziquantel against echinococcus multilocularis in cats.twenty european domestic cats were each infected with 15,000 protoscoleces of echinococcus multilocularis extracted from metacestodes grown in experimentally infected common voles (microtus arvalis). sixteen days after infection, ten cats were treated with a broad-spectrum anthelmintic and acaricide comprising praziquantel and milbemycin oxime. five days later treated and untreated cats were euthanized and the intestine examined for e. multilocularis. five of ten untreated cats were infected wit ...200314627455
preliminary comparative immunocytochemical study of respiratory tract endocrine cells in certain rodents.studies were performed on 3 species belonging to two families: microtidae (7 common voles and 7 pine voles), and muridae - 10 wistar rats. in rodents the airways endocrine cells (ecs) are localised in the epithelium lining the larynx, trachea, bronchi, bronchioles and lung. cgrp-, synaptophysin (sy)-, calcitonin (ct)-, neuron-specific enolase (nse)- and chromogranin a (ca)- immunoreactivity were nearly totally co-localised in ecs. in the region of the tracheo-larynx junction, cgrp- and nse-posit ...200314655129
biological characterisation of cryptosporidium parvum isolates of wildlife rodents in poland.the study was undertaken to characterise the c. parvum isolates originating from naturally infected woodland and field rodents: clethrionomys glareolus (cg), apodemus flavicollis (af) and microtus arvalis (ma). we found that the measurements of oocyst dimensions and oocyst morphology did not allow distinction between the parasite isolates from the 3 rodent species. the mean dimensions were: for cg 4.67 x 4.21, for af 4.65 x 4.14 and for ma 4.66 x 4.16. these 3 groups of isolates have produced si ...200314677907
processes leading to a spatial aggregation of echinococcus multilocularis in its natural intermediate host microtus arvalis.the small fox tapeworm (echinococcus multilocularis) shows a heterogeneous spatial distribution in the intermediate host (microtus arvalis). to identify the ecological processes responsible for this heterogeneity, we developed a spatially explicit simulation model. the model combines individual-based (foxes, vulpes vulpes) and grid-based (voles) techniques to simulate the infections in both intermediate and definite host. if host populations are homogeneously mixed, the model reproduces field da ...200414711588
factors affecting the component community structure of haemoparasites in common voles ( microtus arvalis) from the mazury lake district region of poland.the prevalence and abundance of infections with haemoparasites were studied over a 4-year period in microtus arvalis (common vole, n =321) sampled from fallow grassland sites in north-eastern poland. total species richness was five (prevalence= haemobartonella sp. 63.9%, bartonella spp. 27.7%, babesia microti 9.0%, trypanosoma sp. 8.4% and and hepatozoon lavieri 3.1%) with 76.9% of the voles carrying at least one species and a mean infracommunity species richness of 1.1. variation in species ric ...200414714180
is the prevalence of taenia taeniaeformis in microtus arvalis dependent on population density?populations of common voles microtus arvalis were studied as hosts of the tapeworm taenia taeniaeformis during a 14-yr survey. they were monitored in spring, summer, and autumn in a pastoral ecosystem in eastern france. a total of 7,574 voles were sampled during 2 multiannual population fluctuations. a third fluctuation was sampled during the increase phase only. overall prevalence was lowest in summer (0.6%), increased by 3 times in autumn (1.5%) and a further 5 times in spring (7.8%). analysis ...200314740902
[histologic structure and study of the alkaline phosphatase activity of the vas deferens of field mouse (microtus arvalis p,); state of the adrenal cortex]. 195114849066
[seasonal variations of thyroid activity of field mouse (microtus arvalis)]. 195114849067
[structure of vas deferens in the field mouse (microtus arvalis p) after castration]. 195114936317
[the adrenal cortex in the field mouse (microtus arvalis p) and its modifications after castration]. 195214954617
immunoglobulin g antibodies to borrelia burgdorferi in game animals and small mammals in eastern slovakia.in a survey of game animals and small mammals, the sera of 185 animals were examined for the presence of immunoglobulin g antibodies to the spirochete borrelia burgdorferi sensu lato, which causes lyme borreliosis. these animals comprised 59 fallow deer (dama dama), 56 mouflons (ovis musimon) and 70 small mammals of six different species. the sera of the fallow deer and the mouflons were examined by indirect haemagglutination assay. the sera of the small mammals were examined by modified enzyme- ...200315005560
small mammals (insectivora, rodentia) as a potential source of chlamydial infection in east slovakia.the presence of antibodies against chlamydophila (chlamydia) psittaci in small mammals (insectivora, rodentia) in the region of east slovakia are presented. the hosts were caught in several areas of slovakia in habitats with different levels of anthropogenic disturbance. research was carried out during 2000-2002. the authors examined 1,947 sera coming from 4 insectivore and 10 rodent species. each serum was examined by micromethod of complement binding reactions using antigen chlamydophila (chla ...200415236511
characterization of tula virus from common voles (microtus arvalis) in poland: evidence for geographic-specific phylogenetic clustering.tula virus (tulv), a recently identified arvicolid rodent-borne hantavirus, is harbored by the european common vole (microtus arvalis) in central russia and the czech and slovak republics. we report the isolation and characterization of this hantavirus from m. arvalis captured in poland, a country where human disease caused by hantaviruses has not been recognized. of 34 arvicolid rodents (24 clethrionomys glareolus, 9 m. arvalis, 1 pitymys sp.) captured in lodz and tuszyn, poland, during june to ...200415284484
functional morphology of the ear in fossorial rodents, microtus arvalis and arvicola terrestris.functionally relevant features and parameters of the outer, middle, and inner ear were studied morphologically and morphometrically in two species of voles, smaller microtus arvalis and larger arvicola terrestris. the findings in these fossorial (i.e., burrowing) rodents with components of surface activity were compared with respective findings reported for taxonomically related muroid rodents representing the same size classes but different eco-morphotypes: obligate subterranean rodents (ellobi ...200415487005
frenkelia parasites in a small mammal community. dynamics of infection and effect on the host.a community of small mammals, clethrionomys glareolus, arvicola terrestris, microtus arvalis, m. agrestis, m. subterraneus, apodemus spp. and sorex spp., was studied as hosts of frenkelia glareoli and f. microti in fronche-comté (france). they were monitored in spring, summer and autumn on an area of about 1,350 ha comprising open field, hedgerow network and forest. among 1,714 small mammals examined between july 1992 and october 1993, 47% (178/376) of c. glareolus, 9.9% (14/139) of a. terrestri ...200415490755
zoonotic reservoir of babesia microti in poland.babesiosis is as one of the emerging human and animal diseases transmitted by ticks. it is caused intraerythrocytic parasites of the genus babesia. current evidence of human babesiosis suggests that the majority of cases are involved by babesia divergens and babesia microti piroplasms. as zoonotic reservoir of b. microti serve small mammals--insectivores and rodents. the occurrence of this parasite in natural environment in poland is documented for various regions, in the wide range of mammal ho ...200415787199
[changes in liver of apodemus sylvaticus mice from east-ural radioactive territories].male microtus arvalis mice from radionuclide polluted territories in the south urals (90sr activity of ground--0.2, 2, 500, 800 ci/km2) were used. the 90sr content in a mouse bony skeleton was determined. carbohydrate, energy and protein metabolism, lipid peroxidation processes in liver were studied. the intensification of protein and carbohydrate enzymes. on the increase of antioxidant activity we found the reduction of lipid peroxidation processes. the decrease of microsome oxidoreductases was ...200516080629
hantavirus and arenavirus antibody prevalence in rodents and humans in trentino, northern italy.the spatial and temporal distribution of hantavirus and arenavirus antibody-positive wild rodents in trentino, italy, was studied using immunofluorescence assays (ifa) in two long-term sites trapped in 2000-2003, and six other sites trapped in 2002. the overall hantavirus seroprevalence in the bank voles, clethrionomys glareolus (n=229) screened for puumala virus (puuv) antibodies was 0.4%, and that for apodemus flavicollis mice (n=1416) screened for dobrava virus (dobv) antibodies was 0.2%. ant ...200616371172
[certain aspects of interactions between cohabiting sibling species microtus arvalis and m. rossiaemeridionalis].some aspects of interspecific interactions between sibling species of common vole were studied at the chernogolovka scientific research station (severtsov institute for problems of ecology and evolution, russian academy of sciences) from 1992 to 2001. in the marking plot and indoors, east european vole demonstrated high tolerance to the anthropogenic stress considering that it was the most abundant species in the studied area transformed by human economic activity and that it used buildings as t ...200616521541
babesia microti: prevalence in wild rodents and ixodes ricinus ticks from the mazury lakes district of north-eastern poland.infections of babesia microti (apicomplexa, piroplasmida), a common erythroparasitic protozoon of holarctic rodents, are not widely acknowledged in poland. the presence of this parasite in various species of wild rodents has been well documented throughout the northern temperate zone of north america, europe, and eurasia. however, human babesiosis attributable to infection with b. microti has been reported only from the north-eastern and upper midwestern united states and japan. we recently carr ...200616524774
[the co-occurence of cryptosporidium parvum, giardia spp. and helminth infections in small rodent populations].during long-term (1998-2000) studies on rodent parasite populations in mazury lake district there were collected and analyzed data on co-occurrence of intestinal protozoa (cryptosporidium parvum, giardia spp.) and helminths. there were performed 178 autopsies of common vole microtus arvalis, 85 autopsies of yellow-necked mouse apodemus flavicollis and 386 autopsies of bank vole clethrionomys glareolus. positive effect of helminth infections was found in c. glareolus. voles infected with nematode ...200416859041
[the ecology of cryptosporidium parvum infection in small rodent populations].the prevalence and abundance of cryptosporidium parvum were studied over a three year period (1997-1999) in three species of rodents sampled from forest and abandoned fields in the mazury lake district, poland. the overall prevalence was consistently higher in voles compared with apodemus flavicollis (70.6% in clethrionomys glareolus, 73.0% in microtus arvalis and 27.8% in a. flavicollis). the prevalence and abundance of infection also varied across the 3 years of the study with 1998 being the y ...200116886421
simple epidemiological model predicts the relationships between prevalence and abundance in ixodid ticks.we tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. we used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (apodemus agrarius, apodemus flavicollis, apodemus uralensis, clethrionomys glareolus and microtus arvalis) in central europe. ixodes trianguliceps is active all year round, occurs in the study area in the mountain and su ...200717032480
[epizootology of hemorrhagic fever with renal syndrome in the central chernozem region].a total of 5149 small mammals belonging to 16 species were collected from the lipetsk, voronezh, and belgorod regions (40 administrative districts) in 2003-2004 and examined by elisa and ifa to detect hantavirus antigen and antibodies in the lung tissues. hantavirus circulation was revealed in 13 species, the highest hantavirus activity being detected in field (apodemus agrarius) and small wood (a. (s) uralensis) mice (dobrava-belgrad virus), bank (clethrionomis glareolus) (puumala virus) and co ...200617087062
[wild small mammals are the reservoir hosts of the bartonella genus bacteria in the south of moscow region].a total of 103 blood samples collected from wild small mammals captured in the prioksko-terrasny reserve on the south of moscow region were studied to determine the bartonellae prevalence. the examined species were the yellow-necked mice apodemus flavicollis (35 samples), the european wood mouse apodemus uralensis (10 samples), the bank vole clethrionomys glareolus (51 samples), the house mouse mus musculus (3 samples), the common vole microtus arvalis (2 samples), and the shrew sorex araneus (2 ...200617094651
[helminth fauna of rodents (arvicolidae and muridae) from the kampinos national park].the aim of the study was to examine the parasite fauna of rodents living in natural environment, but in close contact with human seats (small village at the area of the natural big forest).200617120995
seasonal variations in detecting borrelia burgdorferi sensu lato in rodents from north eastern austria.austria is well known as an endemic area of lyme borreliosis. to assess the annual variation of rodent populations that may host agents of lyme borreliosis we collected rodents in northeastern austria. life traps were set out every six weeks during a year consecutively in one each of the three different zones (hohenau, ernstbrunn, vienna woods) that cover the main habitat characteristics of small mammals in northeastern austria. rodents were collected and identified. samples of heart, urine blad ...200617186171
abundance of wild rodents, ticks and environmental risk of lyme borreliosis: a longitudinal study in an area of mazury lakes district of poland.the results of a longitudinal epidemiological survey in two contrasting habitats in an area of the mazury lakes district of poland indicate that both host and vector (ixodes ricinus) densities, may be the most important risk factors for the tick-transmitted spirochetes of borrelia burgdirferi s.l. however, the results also highlight that even related host species, such as the wild rodents apodemus flavicollis and clethrionomys glareolus that share the same habitat, can show quite different dynam ...200617196004
[the structure and evolution of the masmc4 gene of common vole microtus arvalis (arvicolidae, rodentia)].in eukaryotes, the smc (structural maintenance of chromosomes) gene family is represented by at least six genes. some of these genes have tissue-specific homologs. eukaryotic smc structural proteins are the members of biochemical complexes responsible for cohesion of sister chromatids, recombination, repair, regulation of gene expression, and formation of mitotic chromosomes. in the present study, the structure of the smc4 sub-family gene was examined in common vole microtus arvalis. comparative ...200717385313
craniometric identification of three closely related forms of the common vole microtus arvalis sensu lato. 200717515040
the intestinal nematode trichuris arvicolae affects the fecundity of its host, the common vole microtus arvalis.parasites have detrimental effects on host fitness. consequently, they play a major role for host population dynamics. in this study, we investigated experimentally the impact of the nematode trichuris arvicolae on the reproduction of its host, the common vole microtus arvalis. wild common voles were trapped in east of france and reared in standardized conditions before being experimentally infected. infection with trichuris arvicolae did not affect host consumption of food or water. parasitized ...200717520287
puumala and tula hantaviruses in france.the first genome sequences of tula (tulv) and puumala (puuv) hantaviruses undoubtedly originated from france were recovered from tissue samples of european common voles and bank voles captured in jura region. genetic analysis of s and m segments of french puuv strain revealed its highest similarity to strains from neighboring belgium and germany and also from slovakia. on phylogenetic trees, french puuv strain was placed within the central european lineage formed by strains from these three coun ...200717532080
an attempt to control a natural focus of leptospirosis grippotyphosa by rodenticide--a long-term study (1977-2004).the purpose of the study was to suppress a known natural focus of field fever exerting an influence on animal hosts of leptospires--small terrestrial mammals (s.t.m.) by rodenticide. after repeated application of the zinc phosphide rodenticide, the s.t.m. were regularly live-trapped and checked for leptospirosis by dark-field microscopy and culture of their renal tissue and serological examination. isolated leptospira strains were typed by help of rabbit factor sera. the deratization influenced ...200717655177
vectors and reservoirs of cutaneous leishmaniasis in marvdasht district, southern islamic republic of iran.an epidemiological study was made of vectors and reservoirs of cutaneous leishmaniasis in rural regions of marvdasht, fars province, southern islamic republic of iran during 2003-04. using live traps, 126 rodents were collected: 75.4% were meriones libycus, 14.3% cricetulus migratorius and 10.3% microtus arvalis. eight out of 95 meriones libycus (8.4%) were found to be infected with leishmania major, identified by nested-pcr; none of the other rodents were positive. female sandflies were collect ...200717687843
Displaying items 101 - 200 of 577