| antioxidant and antibacterial activity of the beverage obtained by fermentation of sweetened lemon balm
(melissa officinalis l.) tea with symbiotic consortium
of bacteria and yeasts. | kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (camellia sinensis l.) with symbiotic consortium of bacteria and yeasts (scoby). in this study, lemon balm (melissa officinalis l.) was used as the only nitrogen source for kombucha fermentation. during the seven-day fermentation process, ph value, titratable acidity (ta), total phenolic content, phenolic compounds, and antioxidant activity against hydroxyl (˙oh) and 1,1-diphenyl-2-pic ... | 2014 | 27904315 |
| [investigation of the in vitro effects of melissa officinalis l., mentha x piperita l. and ocimum basilicum l. (lamiaceae) essential oils on the cysts and trophozoites of acanthamoeba castellani]. | acanthamoeba species are free living amoeba found widely all over the world. they are responsible for acanthamoeba keratitis (ak), an infection which is especially seen in contact lens users and after minor corneal traumas, that may lead blindness. at present, antifungals and antiseptics are used for the treatment of ak cases, however, some problems such as long treatment periods and the occurrence of side effects, resistance of cyst forms against drugs, emphasize the need for new drugs. there a ... | 2016 | 28124962 |
| ftir spectroscopic evaluation of changes in the cellular biochemical composition of the phytopathogenic fungus alternaria alternata induced by extracts of some greek medicinal and aromatic plants. | in this study, the biological activity of aquatic extracts of selected greek medicinal and aromatic plants to the phytopathogenic fungus alternaria alternata was investigated. lamiaceae species (hyssopus officinalis l., melissa officinalis l., origanum dictamnus l., origanum vulgare l. and salvia officinalis l.) were found to enhance significantly the mycelium growth whereas crocus sativus appears to inhibit it slightly. m. officinalis and s. officinalis caused the highest stimulation in myceliu ... | 2014 | 24657421 |
| drug target identification and elucidation of natural inhibitors for bordetella petrii: an in silico study. | environmental microbes like bordetella petrii has been established as a causative agent for various infectious diseases in human. again, development of drug resistance in b. petrii challenged to combat against the infection. identification of potential drug target and proposing a novel lead compound against the pathogen has a great aid and value. in this study, bioinformatics tools and technology have been applied to suggest a potential drug target by screening the proteome information of b. pet ... | 2016 | 28154518 |
| chemical composition and antimicrobial activity of the essential oil from leaves of algerian melissa officinalis l. | the essential oil obtained from leaves of melissa officinalis l. (family of lamiaceae) growing in algeria, was investigated for its chemical composition and in vitro antimicrobial activity. the chemical composition was determined by hydrodistillation and analyzed by gc/ms and gc-fid. sixty-three compounds were identified in the essential oil, representing 94.10 % of the total oil and the yields were 0.34 %. the major component was geranial (44.20 %). other predominant components were neral (30.2 ... | 2014 | 26417300 |
| attachment and penetration of acyclovir-resistant herpes simplex virus are inhibited by melissa officinalis extract. | medicinal plants are increasingly of interest as novel source of drugs for antiherpetic agents, because herpes simplex virus (hsv) might develop resistance to commonly used antiviral drugs. an aqueous extract of melissa officinalis and the phenolic compounds caffeic acid, p-coumaric acid and rosmarinic acid were examined for their antiviral activity against herpes simplex virus type 1 (hsv-1) acyclovir-sensitive and clinical isolates of acyclovir-resistant strains in vitro. when drugs were added ... | 2014 | 24817544 |
| pp-12 efficacy of a standardized extract of matricariae chamomilla l., melissa officinalis l. and tyndallized lactobacillus acidophilus (h122) compared with lactobacillus reuteri (dsm 17938) and with simethicone for the treatment of infantile colic. | infant colic is a prevalent physiological event of healthy children under 3 months of age, which can disrupt the child's home environment. despite its benign natural history, sometimes it requires a therapeutic approach. there is limited evidence supporting the use of complementary and alternative treatments. the aim of this study was to investigate the effectiveness of a mixture of standardized extract of matricariae chamomilla l., melissa officinalis l. and tyndallized lactobacillus acidophilu ... | 2015 | 26439577 |
| essential oils: in vitro activity against leishmania amazonensis, cytotoxicity and chemical composition. | the current chemotherapy for cutaneous leishmaniosis (cl) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new drugs or effective alternatives to the cl treatment. essential oils (eos) are complex mixtures of secondary metabolites from various plants. it has been shown that several eos, or their constituents, have inhibitory activity against protozoa. thus, this study aims to evaluate the biological acti ... | 2016 | 27825341 |
| melissa officinalis extract inhibits attachment of herpes simplex virus in vitro. | extracts and essential oils of medicinal plants are increasingly of interest as novel drugs for antiherpetic agents, since the herpes simplex virus (hsv) might develop resistance to commonly used antiviral drugs. | 2012 | 22377592 |
| phytochemistry and nematicidal activity of the essential oils from 8 greek lamiaceae aromatic plants and 13 terpene components. | eight essential oils (eos) as well as 13 single terpenes were studied for their nematicidal activity against meloidogyne incognita , for three immersion periods (24, 48, and 96 h). the eos were isolated from eight greek lamiaceae species: melissa officinalis , sideritis clandestina , origanum dictamnus , ocimum basilicum , mentha pulegium , origanum vulgare , vitex agnus castus , and salvia officinalis . the eos nematicidal activity was correlated to their chemical composition as well as to the ... | 2010 | 20527965 |
| antiviral activity of the oseltamivir and melissa officinalis l. essential oil against avian influenza a virus (h9n2). | lemon balm derivatives are going to acquire a novelty as natural and potent remedy for treatment of viral infections since the influenza viruses are developing resistance to the current antivirals widely. oseltamivir, melissa officinalis essential oil (moeo) and their synergistic efficacy against avian influenza virus (aiv) subtype h9n2 were evaluated in vitro in mdck cells at different time exposure by using tcid50, ha, real time pcr and hi assay. the results showed that moeo could inhibit repl ... | 2016 | 27366768 |
| Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice. | Melissa officinalis (L.) (Lamiaceae), a plant known as the lemon balm, is native to the east Mediterranean region and west Asia. Also found in tropical countries, such as Brazil, where it is popularly known as "erva-cidreira" or "melissa", it is widely used in aqueous- or alcoholic-extract form in the treatment of various disorders. The aim was to investigate in vivo its antigenotoxicity and antimutagenicity, as well as its genotoxic/mutagenic potential through comet and micronucleus assaying. C ... | 2011 | 21734832 |
| an evaluation of the inhibitory effects against rotavirus infection of edible plant extracts. | rotaviruses are the single most important cause of severe diarrhea in young children worldwide. the developments of specific, potent and accessible antiviral treatments that restrain rotavirus infection remain important to control rotavirus disease. | 2012 | 22834653 |
| hplc-dad phenolic profile, cytotoxic and anti-kinetoplastidae activity of melissa officinalis. | context melissa officinalis subsp. inodora bornm. (lamiaceae) has been used since ancient times in folk medicine against various diseases, but it has not been investigated against protozoa. objective to evaluate the activities of m. officinalis against leishmania braziliensis, leishmania infantum and trypanosoma cruzi as well as its cytotoxicity in fibroblast cell line. materials and methods the fresh leaves were chopped into 1 cm(2) pieces, washed and macerated with 99.9% of ethanol for 72 h at ... | 2016 | 26864563 |
| melissa officinalis l. decoctions as functional beverages: a bioactive approach and chemical characterization. | lemon balm (melissa officinalis l.) is a member of the lamiaceae family with a long story of human consumption. it has been consumed for decades, directly in food and as a decoction or an infusion for its medicinal purposes. in this manuscript, a detailed chemical characterization of the decoction of this plant is described, encompassing antimicrobial, antioxidant and antitumor activities. rosmarinic acid and lithospermic acid a were the most abundant phenolic compounds. quinic acid, fructose, g ... | 2015 | 26075899 |
| essential oil composition and antifungal activity of melissa officinalis originating from north-est morocco, against postharvest phytopathogenic fungi in apples. | to investigate biological control methods against post-harvest phytopathogenic fungi in apples, tests on the antifungal activity of essential oil of melissa officinalis were carried out. the essential oil, obtained by hydrodistillation, was analyzed by gas chromatography coupled with mass spectrometry (gc-ms). analysis of the essential oil was able to detect 88.7% of the components. the main components are p-mentha-1,2,3-triol (13.1%), p-menth-3-en-8-ol (8.8%), pulegone (8.8%), piperitynone oxid ... | 2017 | 28389346 |
| assessment of inhibitory potential of essential oils on natural mycoflora and fusarium mycotoxins production in wheat. | in the last years essential oils from different plants were used in the prevention of fungi and mycotoxins accumulation in cereals. the most attractive aspect derived from using of essential oils as seed grains protectants is due to their non-toxicity. this study was focused on assessment the inhibitory effect of some essential oils: melissa officinalis (o1), salvia officinalis (o2), coriandrum sativum (o3), thymus vulgaris (o4) mentha piperita (o5) and cinnamomum zeylanicum (o6) against natural ... | 2013 | 23409841 |
| biological activities of asteraceae (achillea millefolium and calendula officinalis) and lamiaceae (melissa officinalis and origanum majorana) plant extracts. | asteraceae (achillea millefolium and calendula officinalis) and lamiaceae (melissa officinalis and origanum majorana) extracts were obtained by applying two sequential extraction processes: supercritical fluid extraction with carbon dioxide, followed by ultrasonic assisted extraction using green solvents (ethanol and ethanol:water 50:50). the extracts were analyzed in terms of the total content of phenolic compounds and the content of flavonoids; the volatile oil composition of supercritical ext ... | 2017 | 28101823 |
| exploring biodiversity in the bacterial community of the mediterranean phyllosphere and its relationship with airborne bacteria. | we studied the structure and diversity of the phyllosphere bacterial community of a mediterranean ecosystem, in summer, the most stressful season in this environment. to this aim, we selected nine dominant perennial species, namely arbutus unedo, cistus incanus, lavandula stoechas, myrtus communis, phillyrea latifolia, pistacia lentiscus, quercus coccifera (woody), calamintha nepeta, and melissa officinalis (herbaceous). we also examined the extent to which airborne bacteria resemble the epiphyt ... | 2012 | 22544345 |
| [antiinflammatory potential of seven plant extracts in the ultraviolet erythema test. a randomized, placebo-controlled study]. | phytotherapeutics are widely used in medicine. the aim of this study was the evaluation of the antiinflammatory potential of seven medical plant extracts using the ultraviolet- (uv)-erythema test. | 2013 | 23337964 |
| adverse effects of herbal medicines: an overview of systematic reviews. | this overview of systematic reviews (srs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (hms). five electronic databases were searched to identify all relevant srs, with 50 srs of 50 different hms meeting our inclusion criteria. most had only minor weaknesses in methods. serious adverse effects were noted only for four hms: herbae pulvis standardisatus, larrea tridentate, piper methysticum and cassia senna. the most severe adverse effects were liver o ... | 2013 | 23472485 |
| analysis of plant galactolipids by reversed-phase high-performance liquid chromatography/mass spectrometry with accurate mass measurement. | the composition of plant membrane lipids was investigated by reversed-phase high performance liquid chromatography mass spectrometry with accurate mass measurement. the data dependent methods for the analysis of monogalactosyldiacylglycerols (mgdgs) and digalactosyldiacylglycerols (dgdgs) have been developed. the optimised chromatographic systems were based on a 2.0 mm i.d. nucleosil c18 column with methanol/water (mgdgs) or acetonitrile/methanol/water (dgdgs) gradients. the galactolipids were i ... | 2012 | 22465211 |
| a review study on the effect of iranian herbal medicines on opioid withdrawal syndrome. | addiction is a chronic and recurring disease that recurrence phenomenon is the most important challenge in treatment of this disease. recent experiences have shown that synthetic drugs have undesirable side effects. recent studies on medicinal plants have shown that they might be effective in treatment of different stages of addiction with lower side effects and costs. the aim of this study was to review the effects of medicinal plants in the treatment of morphine addiction in experimental anima ... | 2015 | 25818661 |
| polyphenols and antioxidant capacity of bulgarian medicinal plants. | extracts of 21 plants used in bulgarian phytotherapy for the treatment of respiratory, gastrointestinal and other inflammatory disorders were screened in vitro for antioxidant activity and phenolic compounds content. plant extracts were prepared as herbal teas following the ethnic use. the water-phase teac (trolox equivalent antioxidant capacity) of the teas were compared to that of the famous tea-like beverages mate, rooibos and honeybush, and to that of green and black tea, well known for thei ... | 2005 | 15588663 |
| how sensitive is melissa officinalis to realistic ozone concentrations? | lemon balm (melissa officinalis, l.; lamiaceae) was exposed to realistic ozone (o3) dosages (80 ppb for 5 h), because high background levels of o3 are considered to be as harmful as episodic o3 regimes. temporal alterations of different ecophysiological, biochemical and structural parameters were investigated in order to test if this species can be considered as an o3-bioindicator regarding changes in background concentrations. at the end of ozone exposure, the plants did not exhibit any visible ... | 2014 | 24321873 |
| effect of arbuscular mycorrhizal fungi on the growth and polyphenol profile of marjoram, lemon balm, and marigold. | the aim of this study is to examine the effect of arbuscular mycorrhizal fungi (amf) colonization on biomass, polyphenol profile, and content of economically important herbs. a pot experiment was performed with marjoram, lemon balm, and marigold applying a commercially available amf mixture for inoculation. major polyphenols were identified using hplc-uv-esi-qtofms on the basis of their uv-vis and mass spectral characteristics, and selected ones were quantified. we showed that amf can provide di ... | 2016 | 27096876 |
| adverse effects of plant food supplements and plants consumed as food: results from the poisons centres-based plantlibra study. | plant food supplements (pfs) are products of increasing popularity and wide-spread distribution. nevertheless, information about their risks is limited. to fill this gap, a poisons centres-based study was performed as part of the eu project plantlibra. multicentre retrospective review of data from selected european and brazilian poisons centres, involving human cases of adverse effects due to plants consumed as food or as ingredients of food supplements recorded between 2006 and 2010. ten poison ... | 2016 | 26948409 |
| toxic potentials of ten herbs commonly used for aphrodisiac effect in turkey. | sexual dysfunction is a serious problem worldwide. in turkey, herbal products are used by some people suffering from sexual dysfunction. despite their therapeutic advantages, some constituents of herbs are potentially toxic and pose health risks because they can be bought from the market without a prescription. therefore, we aimed to determine the safety of herbs possessing aphrodisiac effects, chosen on the basis of their frequency of medicinal use and commercial importance in turkey. | 2015 | 26281312 |
| chestnut and lemon balm based ingredients as natural preserving agents of the nutritional profile in matured "serra da estrela" cheese. | chestnut flowers, lemon balm plants and their decoctions were incorporated into "serra da estrela" cheese, to assess their potential to preserve its nutritional properties and provide new foodstuffs. the analyses were carried out after the normal ripening period of 1month and after 6months of storage. the most abundant nutrients were proteins and fats. the most abundant minerals were ca and na, while c16:0 and c18:1 were the main fatty acids. saturated fatty acids were the most abundant, followe ... | 2016 | 26988492 |
| plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence. | research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. however, a comprehensive review of plant-based anxiolytics has been absent to date. thus, our aim was to provide a comprehensive narrative review of plant-based medicines that have clinical and/or preclinical evidence of anxiolytic activity. we present the article in two parts. in part one, we reviewed herbal ... | 2013 | 23653088 |
| authenticity control of essential oils containing citronellal and citral by chiral and stable-isotope gas-chromatographic analysis. | enantioselective capillary gc on a supelco beta-dex 225 column (heptakis(2,3-di-o-acetyl-6-o-tert-butyldimethylsilyl)-beta-cyclodextrin spb 20poly--20% diphenyl, 80% dimethylsiloxane) and isotope-ratio mass spectrometry, coupled online with capillary gc on an hp5 column have been used for origin-specific analysis and authenticity control of essential oils, for example lemon (citrus limon), lemongrass (cymbopogon citratus and cymbopogon flexuosus), citronella (cymbopogon nardus l.--ceylon type an ... | 2006 | 17089103 |
| hypnotic effect of coriandrum sativum, ziziphus jujuba, lavandula angustifolia and melissa officinalis extracts in mice. | the aim of the present study was to evaluate hypnotic effect of coriandrum sativum, ziziphus jujuba, lavandula angustifolia and melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. three doses of the extracts (250, 500 and 1000 mg/kg of c. sativum and z. jujuba and 200, 400 and 800 mg/kg of l. angustifolia and m. officinalis) were orally administered to male swiss mice (20-25 g) and one hour later pentobarbital (50 mg/kg, i.p.) was inje ... | 2017 | 26779267 |
| medicinal herbs in iranian traditional medicine for learning and memory. | a few factors such as age, stress, and emotions may lead to impaired learning, memory loss, amnesia, and dementia or threats like schizophrenia and alzheimer's disease (ad). iranian traditional medicine (itm) recommends some herbs and herbal preparations for the treatment or prevention of cns problems. | 2016 | 27516676 |
| the efficacy of an herbal medicine, carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. | carmint contains total extracts of melissa officinalis, mentha spicata, and coriandrum sativum, which have antispasmodic, carminative, and sedative effects. as abdominal pain/discomfort and bloating are commonly observed in patients with irritable bowel syndrome, we decided to evaluate the effectiveness of carmint in relieving these symptoms in irritable bowel syndrome patients. we randomly assigned 32 irritable bowel syndrome patients to receive either carmint or placebo, plus loperamide or psy ... | 2006 | 16868824 |
| medicinal plants targeting cardiovascular diseases in view of avicenna. | cardiovascular disease (cvd) is a spectrum of diseases involving the heart and blood vessels, and the first cause of mortality worldwide. medicinal plants have been used for thousands of years to treat cvd. in traditional persian medicine (tpm), there is a special focus on heart diseases. avicenna, a persian physician of the eleventh century compiled a book devoted to this field named "the treatise on cardiac drugs" which is a compendium of tpm knowledge on cvd. avicenna mentioned 50 cardiovascul ... | 2017 | 28215156 |
| medicinal herbs in iranian traditional medicine for learning and memory. | a few factors such as age, stress, and emotions may lead to impaired learning, memory loss, amnesia, and dementia or threats like schizophrenia and alzheimer's disease (ad). iranian traditional medicine (itm) recommends some herbs and herbal preparations for the treatment or prevention of cns problems. | 2016 | 27840509 |
| volatile compounds of lamiaceae exhibit a synergistic antibacterial activity with streptomycin. | bacterial infections cause thousands of deaths in the world every year. in most cases, infections are more serious because the patient is already weakened, and often, the bacteria are already resistant to the antibiotics used. counterparting this negative scenario, the interest in medicinal plants as an alternative to the synthetic antimicrobial drugs is blossoming worldwide. in the present work, we identified the volatile compounds of ethanol extracts of melissa officinalis, mentha sp., ocimum ... | 2014 | 25763039 |
| application of poly(dimethylsiloxane) fiber sol-gel coated onto niti alloy electrodeposited with zirconium oxide for the determination of organochlorine pesticides in herbal infusions. | a pdms fiber sol-gel coated onto an niti alloy previously electrodeposited with zirconium oxide (named niti-zro(2)-pdms) was applied to the determination of organochlorine pesticides (ocps) in infusions of peppermint (mentha piperita l.), lemon grass (cymbopogon citratus stapf), chamomile (matricaria recutita l.), lemon balm (melissa officinalis l.), and anise seeds (pimpinella anisum l.). salting-out effect, extraction time, and extraction temperature were optimized firstly by means of a full-f ... | 2008 | 18666186 |
| detection of pyrrolizidine alkaloids in german licensed herbal medicinal teas. | because of the hepatotoxic, mutagenic, and cancerogenic effects of pyrrolizidine alkaloids (pas) the german federal institute for risk assessment (bfr) recommends not to exceed a daily pa intake of 0.007 µg/kg body weight (0.42 µg/60 kg adult). in a recent study conducted by the bfr, up to 5647 µg pa/kg dried herbal material were detected in tea products marketed as food. | 2015 | 26055130 |
| a randomized double-blind placebo-controlled trial of a standardized extract of matricariae recutita, foeniculum vulgare and melissa officinalis (colimil) in the treatment of breastfed colicky infants. | the aim of this randomized, double-blind, placebo-controlled trial was to investigate the effectiveness and side effects of a phytotherapeutic agent with matricariae recutita, foeniculum vulgare and melissa officinalis in the treatment of infantile colic. | 2005 | 16041731 |
| potential benefits of phytochemicals against alzheimer's disease. | our current therapeutic drugs for alzheimer's disease are predominantly derived from the alkaloid class of plant phytochemicals. these drugs, such as galantamine and rivastigmine, attenuate the decline in the cholinergic system but, as the alkaloids occupy the most dangerous end of the phytochemical spectrum (indeed they function as feeding deterrents and poisons to other organisms within the plant itself), they are often associated with unpleasant side effects. in addition, these cholinesterase ... | 2017 | 28143625 |
| effect of plant extracts on alzheimer's disease: an insight into therapeutic avenues. | alzheimer's disease (ad) is a devastative neurodegenerative disorder which needs adequate studies on effective treatment options. the extracts of plants and their effect on the amelioration of ad symptoms have been extensively studied. this paper summarizes the mechanisms like acetylcholinesterase (ache) inhibition, modification of monoamines, antiamyloid aggregation effect, and antioxidant activity which are actively entailed in the process of amelioration of ad symptoms. these effects are indu ... | 2011 | 21716802 |
| the use of herbal medicine in alzheimer's disease-a systematic review. | the treatments of choice in alzheimer's disease (ad) are cholinesterase inhibitors and nmda-receptor antagonists, although doubts remain about the therapeutic effectiveness of these drugs. herbal medicine products have been used in the treatment of behavioral and psychological symptoms of dementia (bpsd) but with various responses. the objective of this article was to review evidences from controlled studies in order to determine whether herbs can be useful in the treatment of cognitive disorder ... | 2006 | 17173107 |
| medicinal plants and alzheimer's disease: integrating ethnobotanical and contemporary scientific evidence. | the use of complementary medicines such as plant extracts in dementia therapy, varies according to the different cultural traditions. in orthodox western medicine, contrasting with that in china and the far east for example, pharmacological properties of traditional cognitive or memory enhancing plants have not been widely investigated in the context of current models of alzheimer's disease. an exception is ginkgo biloba in which the ginkgolides have antioxidant, neuroprotective, and cholinergic ... | 1998 | 9884179 |