| complete genomic sequence of european bat lyssavirus 1, isolated from eptesicus isabellinus in spain. | all members of the lyssavirus genus cause the disease rabies. european bat lyssavirus 1 (eblv-1) viruses are divided genetically into three groups according to geographic location and host reservoir. we report here the first genome sequence for an eblv-1 isolated from eptesiscus isabellinus in the iberian peninsula, spain. | 2015 | 25676752 |
| cross-platform evaluation of commercial real-time sybr green rt-pcr kits for sensitive and rapid detection of european bat lyssavirus type 1. | this study evaluates the performance of five two-step sybr green rt-qpcr kits and five one-step sybr green qrt-pcr kits using real-time pcr assays. two real-time thermocyclers showing different throughput capacities were used. the analysed performance evaluation criteria included the generation of standard curve, reaction efficiency, analytical sensitivity, intra- and interassay repeatability as well as the costs and the practicability of kits, and thermocycling times. we found that the optimise ... | 2015 | 25785274 |
| second case of european bat lyssavirus type 2 detected in a daubenton's bat in finland. | european bat lyssavirus type 2 (eblv-2) was detected in finland in a daubenton's bat (myotis daubentonii) found in the municipality of inkoo (60°02'45″n, 024°00'20″e). the bat showed neurological signs and was later found dead. the laboratory analysis revealed the presence of lyssavirus, and the virus was characterized as eblv-2. this isolation of eblv-2 was the second time that the virus has been detected in a daubenton's bat in finland. this provides additional proof that eblv-2 is endemic in ... | 2017 | 28946904 |
| [what should the veterinarian know about the european bat lyssavirus?]. | | 2013 | 23638554 |
| seroprevalence dynamics of european bat lyssavirus type 1 in a multispecies bat colony. | we report an active surveillance study of the occurrence of specific antibodies to european bat lyssavirus type 1 (eblv-1) in bat species, scarcely studied hitherto, that share the same refuge. from 2004 to 2012, 406 sera were obtained from nine bat species. blood samples were subjected to a modified fluorescent antibody virus neutralization test to determine the antibody titer. eblv-1-neutralizing antibodies were detected in six of the nine species analyzed (pipistrellus pipistrellus, p. kuhlii ... | 2014 | 25192547 |
| molecular epidemiology of bat lyssaviruses in europe. | bat rabies cases in europe are principally attributed to two lyssaviruses, namely european bat lyssavirus type 1 (eblv-1) and european bat lyssavirus type 2 (eblv-2). between 1977 and 2011, 961 cases of bat rabies were reported to rabies bulletin europe, with the vast majority (>97%) being attributed to eblv-1. there have been 25 suspected cases of eblv-2, of which 22 have been confirmed. in addition, two single isolations of unique lyssaviruses from european insectivorous bats were reported in ... | 2013 | 22937876 |
| erratum to: evolutionary trends of european bat lyssavirus type 2 including genetic characterization of finnish strains of human and bat origin 24 years apart. | | 2015 | 26041725 |
| evolutionary trends of european bat lyssavirus type 2 including genetic characterization of finnish strains of human and bat origin 24 years apart. | among other lyssaviruses, daubenton's and pond-bat-related european bat lyssavirus type 2 (eblv-2) can cause human rabies. to investigate the diversity and evolutionary trends of eblv-2, complete genome sequences of two finnish isolates were analysed. one originated from a human case in 1985, and the other originated from a bat in 2009. the overall nucleotide and deduced amino acid sequence identity of the two finnish isolates were high, as well as the similarity to fully sequenced eblv-2 strain ... | 2015 | 25877913 |
| comparative studies on the genetic, antigenic and pathogenic characteristics of bokeloh bat lyssavirus. | bokeloh bat lyssavirus (bblv), a novel lyssavirus, was isolated from a natterer's bat (myotis nattererii), a chiropteran species with a widespread and abundant distribution across europe. as a novel lyssavirus, the risks of bblv to animal and human health are unknown and as such characterization both in vitro and in vivo was required to assess pathogenicity and vaccine protection. full genome sequence analysis and antigenic cartography demonstrated that the german bblv isolates are most closely ... | 2014 | 24828330 |
| bat rabies surveillance in finland. | in 1985, a bat researcher in finland died of rabies encephalitis caused by european bat lyssavirus type 2 (eblv-2), but an epidemiological study in 1986 did not reveal eblv-infected bats. in 2009, an eblv-2-positive daubenton's bat was detected. the eblv-2 isolate from the human case in 1985 and the isolate from the bat in 2009 were genetically closely related. in order to assess the prevalence of eblvs in finnish bat populations and to gain a better understanding of the public health risk that ... | 2013 | 24011337 |
| detection of european bat lyssavirus 2 (eblv-2) in a daubenton's bat (myotis daubentonii) from magdeburg, germany. | in europe bat rabies in daubenton's bats (myotisdaubentonii) and in pond bats (myotis dasycneme) caused by the european bat lyssavirus 2 (eblv-2) has been confirmed in less than 20 cases to date. here we report the second encounter of this virus species in germany. a daubenton's bat found grounded in the zoological garden in magdeburg died shortly after. in the frame of a retrospective study the bat carcass was eventually transferred to the national reference laboratory for rabies at the friedri ... | 2012 | 22712424 |
| lyssavirus-reactive antibodies in swedish bats. | to study the presence of european bat lyssavirus (eblv) infections in bat reservoirs in sweden, active surveillance was performed during the summers from 2008 to 2013. | 2016 | 27974131 |
| comparative analysis of european bat lyssavirus 1 pathogenicity in the mouse model. | european bat lyssavirus 1 is responsible for most bat rabies cases in europe. although eblv-1 isolates display a high degree of sequence identity, different sublineages exist. in individual isolates various insertions and deletions have been identified, with unknown impact on viral replication and pathogenicity. in order to assess whether different genetic features of eblv-1 isolates correlate with phenotypic changes, different eblv-1 variants were compared for pathogenicity in the mouse model. ... | 2017 | 28628617 |
| molecular epidemiology and evolution of european bat lyssavirus 2. | bat rabies cases in europe are mainly attributed to two lyssaviruses, namely european bat lyssavirus 1 (eblv-1) and european bat lyssavirus 2 (eblv-2). prior to the death of a bat worker in finland in 1985, very few bat rabies cases were reported. enhanced surveillance in the two subsequent years (1986-1987) identified 263 cases (more than a fifth of all reported cases to date). between 1977 and 2016, 1183 cases of bat rabies were reported, with the vast majority (>97%) being attributed to eblv- ... | 2018 | 29303971 |