| infections due to adenovirus type 8 in the united states. i. an outbreak of epidemic keratoconjunctivitis originating in a physician's office. | | 1963 | 14025592 |
| infections due to adenovirus type 8 in the united states. ii. community-wide infection with adenovirus type 8. | | 1963 | 14025591 |
| genetic characterisation of adenovirus type 8 isolated in hiroshima city over a 15 year period. | to investigate the genetic differences among the strains of adenovirus type 8 (ad8) circulating in hiroshima city, japan, and to study their circulation pattern. | 2003 | 12560390 |
| adenovirus type 37 uses sialic acid as a cellular receptor on chang c cells. | epidemic keratoconjunctivitis (ekc) is a severe eye infection caused mainly by adenovirus type 8 (ad8), ad19, and ad37. we have shown that the ekc-causing adenoviruses use sialic acid as a cellular receptor on a549 cells instead of the coxsackie-adenovirus receptor, which is used by most adenoviruses. recently, wu et al. (virology 279:78-89, 2001) proposed that ad37 uses a 50-kda protein as a receptor on chang c conjunctival cells and that this interaction is independent of sialic acid. accordin ... | 2002 | 12163603 |
| no sequence variation in part of the hexon and the fibre genes of adenovirus 8 isolated from patients with conjunctivitis or epidemic keratoconjunctivitis (ekc) in norway during 1989 to 1996. | several local epidemics of keratoconjunctivitis/conjunctivitis caused by adenovirus type 8 (ad8) occurred in norway from august 1995 to may 1996. a smaller epidemic occurred in 1992. the ad8 hexon forms the surface of the virion and contains the hypervariable regions loop i(1) and loop i(2). the fibre mediates the primary contact with cells. sequence variation in hexon and fibre genes might play an important role in the pathogenicity of adenoviruses. the aim of this study was to investigate the ... | 2001 | 11429431 |
| corneal epithelial changes due to adenovirus type 8 infection. a non-contact photomicrographic in vivo study in the human cornea. | to investigate corneal epithelial changes in human adenovirus type 8 (ad8) infection, and compare them with herpes simplex virus type 1 (hsv1) changes. | 2000 | 10726788 |
| sequence and transcriptional analysis of terminal regions of the fowl adenovirus type 8 genome. | fowl adenovirus (fadv) type 1, celo strain has no homologies to mastadenovirus e1a, e1b, e3 and e4, which regulate virus gene expression, dna replication and virus-host interaction. similarly, the right 5 kb and left 15 kb ends of celo virus dna are non-homologous to mastadenoviruses. to compare celo virus with another fadv, 7.5 kb of the left and 17 kb of the right ends of fadv type 8 (strain a-2a) were sequenced and nine and 17 open reading frames (orfs), respectively, were found. this fadv-8 ... | 1998 | 9780058 |
| adenovirus type 8 epidemic keratoconjunctivitis in an eye clinic: risk factors and control. | epidemic keratoconjunctivitis (ekc) due to adenovirus type 8 affected 126 (7%) of 1870 ophthalmology clinic patients during an outbreak. risk factors and mode of transmission were studied by comparing cases (n = 58) and controls (n = 200) for exposure to risk factors. pneumotonometry (odds ratio [or], 10.5; 95% confidence interval [ci], 4.0-27.7), multiple clinic visits (or, 5.9; 95% ci, 3.3-10.6), and contact with an infected physician (or, 3.3; 95% ci, 1.2-9.0) were significant risk factors fo ... | 1993 | 8501319 |
| adenovirus type 8 conjunctivitis outbreak in a neonatal intensive care unit. | an outbreak of adenovirus type 8 conjunctivitis occurred in seven premature infants who had undergone ophthalmological examination four to seven days previously. three of the affected infants, treated with steroids because of bronchopulmonary dysplasia, showed systemic manifestations and deterioration of their respiratory disease. second and third waves affected nine staff and 12 family members. | 1993 | 8323370 |
| development and preliminary evaluation of an enzyme immunosorbent assay for the detection of adenovirus type 8. | epidemic keratoconjunctivitis (ekc) is a highly contagious adenoviral ocular infection which can occur in outbreaks and is predominantly caused by adenovirus type 8 (ad8). detection and typing of this virus after isolation is generally by serum neutralisation or more complex molecular techniques. these methods can be time consuming particularly during outbreaks. therefore, an ad8 specific antigen capture enzyme immunosorbent assay (eia) was developed as a rapid and cost effective diagnostic meth ... | 1994 | 7534818 |
| restriction endonuclease cleavage analysis of adenovirus type 8: two new subtypes from patients with epidemic keratoconjunctivitis in sapporo, japan. | we studied the restriction endonuclease cleavage patterns of dnas of adenovirus type 8 (ad 8) isolated from epidemic keratoconjunctivitis cases. dnas of 25 ad 8 isolates collected during the period from 1975 to 1981 in sapporo were subjected to enzymatic cleavage with psti, bamhl , hindiii and sali. on the basis of the cleavage patterns, the isolates were divided into two subtypes, a and b, both different from trim strain used as the ad 8 prototype strain. subtype a was prevalent in the period f ... | 1983 | 6328068 |
| [the effects of topical steroids in epidemic kerato-conjunctivitis (author's transl)]. | fifty-three patients with proven adenovirus type 8 infection were treated at random, in a prospective study, with either artificial tears or topical steroids over six weeks. severe cases of nummular keratitis, as well as deep keratitis and slight iritis, were significantly less frequent under steroids. no difference existed with respect to the course of the conjunctivitis and the frequency of a superficial punctate keratitis. furthermore, the overall frequency of nummular keratitis was equal in ... | 1980 | 6256579 |
| restriction site maps of the human adenovirus type 8 dna. | restriction site maps of human adenovirus 8 (ad h 8) were constructed with bamhi, hindiii, psti, sali and kpni endonucleases. the genome size was found to be 22.1 to 22.3 x 10(6) mr. comparison of the results with the data available on h ad subgenera a, b, c showed that the sali enzyme revealed subgenus-specific differences in the genomes. similar patterns of the sali fragments in both type 8 and 10 suggest that the differences were specific for the subgenus d of h ad. | 1983 | 6138993 |
| [epidemic keratoconjunctivitis. laboratory study of patients infected with adenovirus type 8]. | the authors tried to detect, using different methods, the causal agent of the disease in eight patients with epidemic keratoconjunctivitis. from the conjunctival sacs of one ambulatory patient and six of seven patients hospitalized on account of other eye diseases they isolated 11 strains of adenovirus type 8 on cell cultures from human embryonic lungs. using direct and indirect elisa, they detected adenovirus antigen in four of seven examined smears from the conjunctival sac without previous cu ... | 1989 | 2551515 |
| two outbreaks of adenovirus type 8 keratoconjunctivitis with different outcome. | in 1993, a case of adenovirus type 8 keratoconjunctivitis acquired in central europe was the starting point of an outbreak in malmö, sweden. of the 33 diagnoses cases, 23 were infected nosocomially. in 29 the diagnosis was verified by virus culture. the outbreak was recognised 15 days after the appearance of the first secondary case. nosocomial transmission was stopped by protective measures which didn't include separation of the infected patients from others. epidemiologic investigation disclos ... | 1995 | 8646586 |
| a comparison of methods for detecting adenovirus type 8 keratoconjunctivitis during a nosocomial outbreak in a neonatal intensive care unit. | an outbreak of epidemic keratoconjunctivitis (ekc) due to adenovirus (ad) type 8 and involving 14 members of the hospital staff and 33 neonates admitted to the neonatal intensive care unit of the local university hospital occurred between september and december 2000 in pavia, italy. the outbreak was preceded by an outbreak of ekc within the community. | 2003 | 14522064 |
| an outbreak of adenovirus type 8 keratoconjunctivitis in a nursing home in madrid. | this work describes and analyses an outbreak of epidemic keratoconjunctivitis which occurred in 2001 and 2002 in a nursing home for the elderly in leganes (an area of madrid). this is the first such published case in spain with these characteristics and this serotype identification. sociodemographic characteristics, epidemic curve and attack rates are described. comparisons of the data were carried out using a chi2 test for qualitative variable and t-test for quantitative. factors associated wit ... | 2004 | 15075484 |
| tolerability and efficacy of n-chlorotaurine in epidemic keratoconjunctivitis--a double-blind, randomized, phase-2 clinical trial. | the aim of this study was to assess the tolerability and efficacy of n-chlorotaurine (nct), an endogenous antimicrobial agent, in epidemic keratoconjunctivitis. in a prospective double-blind, randomized phase 2b study, the infected eyes were treated for 7 days with eye drops containing 1% aqueous solution of n-chlorotaurine (33 subjects) or gentamicin (27 subjects, control group). adenovirus types 3, 4, 8, 19, and 37 were detected in 39 subjects (65%), enteroviruses in 8 (13.3%), and staphylococ ... | 2005 | 15857282 |
| analysis of the complete genome sequence of epidemic keratoconjunctivitis-related human adenovirus type 8, 19, 37 and a novel serotype. | we determined the complete genome sequence of epidemic keratoconjunctivitis (ekc)-related human adenoviruses (hadvs). we analysed a total of 12 hadv strains; three prototype strains and two hadv-8, three hadv-19 and three hadv-37 clinical isolates from ekc patients in japan, and one novel serotype of hadv. genome organization of these serotypes was identical to those of the recently determined hadv-19 and hadv-37. the identities of the whole genome were over 99 % among strains from the same sero ... | 2009 | 19264666 |
| the disinfection efficacy of menicare soft multipurpose solution against acanthamoeba and viruses using stand-alone biocidal and regimen testing. | to assess the disinfection efficacy of menicare soft contact lens multipurpose solution against acanthamoeba and viruses in suspension and when inoculated on to contact lenses and subjected to rub-and-rinse or no-rub-and-rinse care regimes. | 2010 | 20107417 |
| genome variability of human adenovirus type 8 causing epidemic keratoconjunctivitis during 1986-2003 in japan. | epidemic keratoconjunctivitis (ekc) is a contagious acute conjunctivitis associated with community-acquired infection. human adenovirus type 8 (hadv-8) is one of the major serotypes isolated from patients with ekc. dna restriction enzyme analyses were performed to investigate the genetic characteristics of the isolates and their chronological pattern. | 2011 | 22171158 |