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research of canine filariasis in trapani province (western sicily). morphology on sem of male dirofilaria repens.the prevalence of canine filariasis was investigated in 4 municipalities of trapani province (campobello di mazara, castelvetrano, marsala and mazara del vallo), an area where 8 human cases of dirofilariasis due to dirofilaria (nochtiella) repens have occurred during the last decade. blood samples were collected late in the afternoon, during august and september 1995, and examined by knott technique for the presence of microfilariae. sixtythree (29.3%) out of 215 domestic dogs (98 males, 117 fem ...19979802102
adult dirofilaria repens in a subcutaneous granuloma on the chest of a dog.a 10-year-old, 9 kg, intact male crossbred dog was treated for nasal mites with milbemycin oxime using a dose of 1 mg/kg bodyweight orally, three times at 10-day intervals. one month after the initiation of this treatment a subcutaneous nodule developed on the sternum of the dog. the nodule was removed and found to contain a single, 82 mm long, thread-like nematode. several exotic parasites were suspected as possibilities because the dog had been imported to norway from south africa. microfilari ...19989888115
ocular filariasis: not strictly tropical.a 65-year-old man consulted for a discomfort in the right eye that had suddenly appeared the evening before. the examination revealed a white worm localized under the temporal bulbar conjunctiva. after extraction, the parasitological characteristics identified the worm as dirofilaria repens (nochtiella subgenus). this is a parasite of canids and felids, usually nonpathogenic to humans, but which can be transmitted through mosquito bites, especially around the mediterranean basin. the simple extr ...199910202297
human dirofilaria repens infection in hungary: a case in the spermatic cord and a review of the literature.orchiectomy was performed in a 37-year-old hungarian man exhibiting a swelling in his right testicle. histology revealed a nodule attached to the spermatic cord, consisting of a granulomatous tissue around sections of a nematode. the worm was identified as dirofilaria repens, an uncommon parasite in hungary. as the patient had been abroad only in italy where cases of dirofilariosis in dogs and humans are relatively frequent, it is assumed that the infection might have been acquired in that count ...199910213931
pitfalls and difficulties in histological diagnosis of human dirofilariasis due to dirofilaria (nochtiella) repens.the authors have conducted a histologic study of over 90 cases of dirofilaria infection in man due to dirofilaria repens, the most extensive study of its kind in the world. on the basis of their findings, they illustrate the diagnostic difficulties that may arise when regressive phenomena render the parasite's morphologic characteristics largely or completely unrecognizable. these phenomena are due to the death of the filaria inside the inflammatory nodule weeks or months prior to surgical remov ...199910342109
breast infection due to dirofilaria repens: report of two new italian cases and revision of the literature.two new cases of human dirofilariasis, occurred in women aged 46 and 52 years, respectively, both living in lombardy (northern italy) are reported. dirofilaria repens nematodes were localised in the breast in both cases. in one of them the parasite was accidentally extracted while the patient underwent a fine needle aspirate. the international literature records 30 cases of breast dirofilariasis. except in rare cases, the parasite was located subcutaneously in the breast, and nested in a nodule. ...199810376282
presence of dirofilaria repens and an insect immunocyte (plasmatocyte) in a human subcutaneous nodule, induced by a mosquito bite.it is well known that the nematode dirofilaria repens is transmitted to humans by vector mosquito bite. examination of a fine needle aspiration biopsy drawn from a month-old nodule on the chest of a woman, residing in garlasco, province of pavia, northern italy, revealed the presence of not only one immature female of d. repens, but also some scattered cells that we believe to be mosquito's blood cells, plasmatocytes (immunocytes). we presume that plasmatocytes were carried into the bite wound w ...199810376295
dirofilaria repens presenting as a subcutaneous nodule in the penis. 199910510134
dirofilaria repens infection in a dog in israel.only one case of canine infection with dirofilaria repens has been reported in israel to date; this occurred in 1934. this publication, 65 years later, represents the second case of d. repens infection in a dog in israel. this dog was infected locally since it was born in israel and was never taken abroad, suggesting that the life cycle of the filaria was completed in israel. since dogs, cats, and foxes serve as a reservoir for the filaria and these are abundant in israel, and mosquitoes of the ...199910548301
endoscopic removal of an intraorbital "tumor": a vital surprise.we present the first case report of an endoscopic removal of a living worm, species dirofilaria repens, from the orbital cavity. as of today, over 410 cases of dirofilaria repens infections in man are recorded in world literature, six of which were localized in the orbital cavity. in austria we know of four cases of an infection with this parasite, but none in the orbit. dirofilaria repens is widespread only in the old world, particularly in southern and eastern europe, in asia minor, and in cen ...199910631404
the prevention of dirofilaria repens infection with ivermectin/pyrantel chewables.this trial was conducted to test the efficacy of ivermectin/pyrantel chewables in preventing the development of dirofilaria repens in dogs. the trial included 155 dogs from an endemic area in north-western italy. prior to enrollment in the study, none of the dogs had microfilariae of d. immitis or d. repens in a concentration test, and all dogs were also seronegative for adult heartworm antigen. animals remained with their owners and were dosed six times, at monthly intervals according to body w ...199810645558
nine more cases of human infections by dirofilaria repens diagnosed in italy by morphology and recombinant dna technology.dirofilariosis is a mosquito-borne disease of carnivors due, in italy, to dirofilaria repens and d. immitis species which are sympatric in many areas. nine more cases of human infection are here reported, detected in italian patients living in northern regions (where d. immitis and d. repens are largely present), in tuscany (where d. repens is more frequent than d. immitis), and in sicily (where d. immitis is present only sporadically). the nematodes surgically removed (7 female and 2 male speci ...199810645559
[human dirofilariasis in corsica: a new local case. review of reported cases].a case of human dirofilariasis with dirofilaria (nochtiella) repens, located in a subcutaneous nodule of the arch of the foot is reported in a 64-year-old man living in the surroundings of porto vecchio in corsica. the histological examination of this nodule has revealed a gravid female nematode, dead some weeks or months before its surgical excision. it is the second case of human dirofilariasis observed in a patient living on the island. the authors are surprised by the number of patients repo ...199910690464
histopathological diagnosis of subcutaneous dirofilaria repens infection in humans.the host tissue response in humans, based on a study of biopsies of 14 subcutaneous nodules caused by dirofilaria repens is described. the response was characterized by accumulation of eosinophilic material or eosinophilic pus adjacent to the parasite with surrounding granulomatous inflammation associated with extensive eosinophil infiltration of the surrounding tissue. unlike with fungal lesions, fat necrosis was conspicuously absent. nodules were all less than 3 cm in size. fifteen percent of ...199910774712
[a new case of subcutaneous dirofilariasis].authors describe another case of subcutaneous dirofilariasis due to dirofilaria (nochtiella) repens in france. a 26-year-old woman was infected while on vacation in cap d'agde on the mediterranean coast. the patient presented with a subcutaneous nodule in the right subclavicular region. examination of the nodule after surgical excision revealed the presence of a worm identified as an immature female dirofilaria repens. dirofilariasis is a rare anthroponotic disease encountered only in the old wo ...199910816750
[dirofilariasis, an emerging and underestimated zoonoses in france].a total of 71 cases of dirofilariasis due to dirofilaria repens and two cases of pulmonary dirofilariasis due to dirofilaria have been reported in france. as a result france ranks second after italy in the incidence of this emerging zoonoses that has been given little attention (48 p. 100 of cases in the last ten years). most human infections (80 p. 100) have occurred in mediterranean areas but in the last ten years a few cases have been reported in southwestern france and at least one case was ...199910816755
unusual organization of the 5s ribosomal spacer in dirofilaria repens: absence of a canonical spliced leader 1 sequence.comparing the 5s ribosomal rna spacer of dirofilaria repens and d. immitis, we found that in d. repens pcr generates two amplification products. in both products, the putative spliced leader 1 sequences (sl1) show some nucleotide substitutions compared to the canonical sl1 sequence of nematodes. sl i is a short sequence transferred to the 5' end of most messenger rnas through a trans-splicing reaction. all the other filariae studied thus far amplify a single fragment showing a canonical sl1 sequ ...200010894477
[conjunctival dirofilariasis caused by dirofilaria repens: report of a french case].dirofilariasis involving dirofilaria repens is an exceedingly rare event in france. most cases have involved subcutaneous lesions but ocular and peri-ocular involvement have been observed. the present report describes a case of dirofilariasis involving the conjunctiva in a 61 year-old-man in france. onset was characterized by the sudden appearance of painful conjunctival cyst. clinical examination and laboratory tests did not allow diagnosis. opening the cyst and extracting the parasite allowed ...199510906984
molecular diagnosis of dirofilaria repens is not a dream. 200010928825
canine dirofilariosis in two cities of southeastern spain.several cases of human subcutaneous/ocular dirofilariosis caused by dirofilaria repens from an area in the southeastern spain where previous epidemiological studies have shown a very low prevalence of this species in dogs, have been studied in our laboratory. since the prevalence of this species in dogs did not correspond to the incidence of human cases in the zone studied, a preliminary epidemiological survey was carried out on 114 dog blood samples from two kennels and one veterinary clinic. k ...200010936548
new human dirofilarioses in hungary.about ten cases of filariosis have recently been recorded in the hungarian medical literature, six of them caused by dirofilaria repens. dirofilaria repensis a mosquito-transmitted filaroid worm in the subcutaneous tissue of dogs and cats in the temperate areas of the old world. it accidentally infects man, too, and can remain unidentified due to physicians, poor knowledge of the parasite. in the last two years six new dirofilaria repensinfections have been found in various parts of the country: ...200010936791
the incrimination of aedes (stegomyia) aegypti as the vector of dirofilaria repens in nigeria.six local species of culicides were identified as the common mosquitoes in zaria, out of 15 species captured using various adult and larval collection methods. these common culicides are culex pipiens fatigans, anopheles gambiae grp., mansonia africana, culex pipiens pipiens, aedes (stegomyia) aegypti and aedes vittatus. they were each fed directly on a local dog naturally infected with dirofilaria repens to evaluate their refractoriness/susceptibility to dirofilarial infection. in a number of d ...200010996744
microfilaremia from a dirofilaria-like parasite in greece. case report.in europe, zoonotic filarial infections in humans are caused by two species, dirofilaria immitis and dirofilaria repens. these parasites are associated mainly with embolic infarcts of the pulmonary artery and subcutaneous nodules, respectively. an unusual dirofilarial infection in a greek patient who showed marked eosinophilia and microfilaremia is presented. although the identification of dirofilaria species is not conclusive, this report is the first on a case of microfilaremia from a dirofila ...19989531965
human dirofilariasis.subcutaneous and pulmonary dirofilariasis in humans appears to be a frequent disease in endemic areas, notably the mediterranean region. following increased air travel in recent years, the incidence of human dirofilariasis has increased in tourists as well.19968970844
development of dirofilaria and setaria nematodes in aedes albopictus.the development of dirofilaria repens, d immitis and setaria labiatopapillosa up to l3 stage was documented in a laboratory colony of aedes albopictus originating from specimens collected in civitavecchia (central italy). the susceptibility of ae albopictus and its plastic trophic habits, strongly suggest that this mosquito may contribute to the spreading of these nematodes in the country. it is particularly emphasized the danger for human health of an increased probability of transmission of di ...19958778656
[human periorbital dirofilariasis].we present the case of a 72 year-old-woman with recurrent periocular inflamatory mass caused by an infection with dirofilaria repens. the zoonotic infection is spreading by mosquito vectors from dogs to humans. residence in endemic areas (ex-ussr, italy, sri lanka, southeastern united states) should always be suspected in patients with this type of symptomatology. the treatment is curative by the extraction of the pseudotumoral mass.19968729842
[subcutaneous dirofilaria (nochtiella) repens infection in man--report of the first case in austria and review of the literature (author's transl)].a 39-year-old female patient developed migratory skin nodules 4 months after a vacation in greece. the patient observed a total of 17 nodules moving over the trunk to the left thigh, where a subcutaneous lesion was excised, yielding a parasite measuring 0.5 mm x 7 cm. it was classified as dirofilaria (nochtiella) repens. since this is the first case observed in austria, an exact description of subcutaneous dirofilariasis, its geographical distribution and a review of the literature is presented.19817281684
in vitro cultivation of dirofilaria repens microfilariae up to the sausage stage. 19675590547
fine needle aspiration of retroperitoneal human dirofilariasis with a pseudotumoral presentation.the accidental finding of a pseudotumoral para-aortic mass in a 60-year-old woman led to the performance of a fine needle aspiration (fna) biopsy under ultrasonographic guidance. the milky aspirate was centrifuged and processed as a cell block. the examination of sections confirmed the lymphatic origin of the sample, but also revealed some unexpected parasitic structures. while a complete identification could not be made on a few sections, the morphologic and epidemiologic evidence suggested dir ...19901967124
[human dirofilariasis in italy].since 1971, at the laboratory of parasitology, faculty of veterinary medicine, university of bologna, 30 cases of human dirofilariasis were observed out of the 101 cases reported in italy. the causative agent was identified in nearly all the cases as dirofilaria repens (nematoda, filarioidea) a parasite relatively common in the dog in italy. 23 cases were localized in the subcutaneous tissue, 4 in the submucosa and 3 in the lungs. in the majority of the cases the diagnosis had been misinterprete ...19911814252
infection of man by dirofilaria repens.dirofilaria repens, a natural parasite of dogs and cats in europe, asia, and africa, sometimes infects man. in man the worms are usually in subcutaneous tissues or in the orbit. a case is herein reported in which a non-gravid, adult dirofilaria, probably d. repens, was in the subcutaneous tissue of a resident of wisconsin. the patient, however, acquired the infection 8 years previously in greece.1978727332
subcutaneous dirofilariasis in okinawa, japan.a nematode within a subcutaneous nodule excised from an elderly okinawan man has been tentatively identified in sections as an immature dirofilaria repens--the first to be reported from japan.1979434315
5 s ribosomal spacer sequences of some filarial parasites: comparative analysis and diagnostic applications.we have amplified by pcr the sequences of the 5 s ribosomal spacer of setaria labiatopapillosa and foleyella furcata. after sequencing, these sequences have been compared with those of dirofilaria immitis and dirofilaria repens. two major goals have been achieved: (i) the establishment of a multiplex pcr-based diagnostic assay, applicable to identify the four species in vertebrate and invertebrate hosts; (ii) the identification, in s. labiatopapillosa and f. furcata, of a canonical spliced leade ...200011040091
[a case of an ocular form of dirofilariasis].a rare ophthalmic involvement is described. patient s. aged 60 years was treated for 6 months without effect for allergic conjunctivitis of the right eye, after which a free moving helminth was detected under the bulbar conjunctiva. the parasite was removed, and symptoms of toxic allergic conjunctivitis rapidly regressed. the helminth was identified as dirofilaria repens, its size was 120 x 2 mm.200011055226
dirofilaria repens in a cat with acute liver failure.acute liver failure was diagnosed in a 12-year-old cat. fine needle aspirate cytology revealed high numbers of unsheathed microfilariae and a hepatocellular reaction with no evidence of bacterial infection. the microfilariae were identified as those of dirofilaria repens by acid phosphatase staining. the high number of microfilariae seen in both the blood and the liver aspirate samples as well as the favourable response to ivermectin amongst other drugs administered, is suggestive that d. repens ...200011205171
subcutaneous infection caused by dirofilaria repens imported to slovenia.a case of human subcutaneous dirofilariasis is presented. a complete nematode removed from the tumour in the occipital region of a 61-year-old woman was identified, on the basis of its anatomical and histological characteristics, as a nongravid adult female of the species dirofilaria repens. the patient had probably been infected on the canary islands, spain, 7 months previously. in the future, the clinical and laboratory staff in slovenia will have to be more alert to the possibility of dirofil ...200111243759
[human dirofilariasis in france: new data confirming the human transmission of dirofilaria repens to the north of the 46 degree north latitude]. 200011258073
improved detection of dirofilaria repens dna by direct polymerase chain reaction.diagnosis of human infection by dirofilaria repens, depends mainly on microscopic evaluation of tissue cross-sections and the macroscopic characteristics of the worm. tissue degeneration and/or poor specimen preparation practices however, often render many cases of subcutaneous dirofilariasis elusive to such morphological diagnostic approaches. the early pcr protocols, developed to satisfy these complex diagnostic needs, failed to amplify dirofilariae dna from formalin preserved material. to ove ...199911269275
dirofilariasis due to dirofilaria repens in italy, an emergent zoonosis: report of 60 new cases.sixty new cases of human dirofilariasis due to dirofilaria repens, occurring in italy between 1990 and 1999, are presented. this is the most extensive case study of this zoonosis reported worldwide by a single study group. the aim is to utilize this large experience to characterize the different histopathological findings in the parasitic lesions in man.200111318900
[dirofilariasis in the practice of an ophthalmologist].a youth aged 16 was hospitalized in ophthalmological department for surgical treatment of the lower eyelid chalazion of the left eye. no helminths were diagnosed before surgery. opening of the chalazion resulted in release of a thread-shaped helminth into the wound; the helminth was identified as immature dirofilaria repens female. a solid connective tissue capsule formed round the parasite. routes of dirofilarias infection, its vectors, permanent, intermediate, and accidental hosts, and prevale ...200111521439
subconjunctival dirofilariasis in india.human dirofilariasis caused by dirofilaria repens, have been reported to occur widely throughout asia, europe and africa. reports of this infection from india are however limited. herein we report a case of subconjunctival dirofilariasis from karnataka state of india. a 42 year old man presented with a history of pain and swelling in the left eye. a live parasite measuring 3.5cm in length was surgically removed from the nodular swelling in the conjunctiva. the parasite was identified as dirofila ...200111556571
human dirofilariasis due to dirofilaria (nochtiella) repens: an update of world literature from 1995 to 2000.following on from their review of 1995 (pampiglione et al.), the authors present an update of human cases of dirofilariasis due to dirofilaria (nochtiella) repens (nematoda, filarioidea, onchocercidae) reported in the world literature. cases of the parasitosis published from 1995 to 2000 are reported country by country. the essential data are presented in tabular form and the clinical, parasitological, histopathological, epidemiological features are analysed. 372 new cases spread over 25 countri ...200011686084
histochemical differentiation of dirofilaria immitis, dirofilaria repens and acanthocheilonema dracunculoides microfilariae by staining with a commercial kit, leucognost-sp.the diagnosis of canine heartworm infection is based upon the presence of circulating dirofilaria immitis microfilariae or on techniques for the detection of serum antibodies or antigens. in the first of these, discrimination between d. immitis, d. repens and acanthocheilonema dracunculoides microfilariae is based upon the acid phosphatase histochemical stain. in this paper, we propose an alternative technique for histochemical staining using a commercial kit test of naphthol-as-ol (leucognost-s ...200111705664
a prevalence survey and risk analysis of filariosis in dogs from the mt. vesuvius area of southern italy.a dog microfilariae prevalence and risk factor survey was conducted in 51 contiguous municipalities of the mt. vesuvius area (campania region, southern italy) in order to add data to the limited epidemiological information available regarding filarial worms in this zone. between may 1999 and june 2000, blood samples were collected from 351 asymptomatic dogs. blood samples were examined using a modified knott's technique and histochemical staining in order to count and identify microfilariae. the ...200111777604
dirofilariasis of breast: report of two cases diagnosed by fine-needle aspiration biopsy.we report on 2 cases of dirofilariasis of the breast occurring in adult chinese females residing in hong kong. the diagnosis was made by fine-needle aspiration biopsies. the direct smears contained numerous acute inflammatory cells, including eosinophils. a partially necrotic adult nematode of about 400-450 microm in diameter was identified in the cell-block sections of each case. the worm was characterized by a thick cuticle with longitudinal cuticular ridges and fine transverse surface striati ...200211782082
[autochthonous subcutaneous dirofilariasis in israel].canine dirofilariasis has been recognized for over 300 years, but human dirofilariasis has received relatively little attention. sporadic cases of human dirofilariasis have been reported in israel. dogs, cats and foxes are the reservoir, mosquitoes of the genera culex and aedes are the vectors and humans are the accidental hosts.200111789292
[difficulties in diagnosis of human dirofilariasis outside known enzootic areas].human non-visceral dirofilariasis, a mosquito-borne disease of carnivores (dogs), is chiefly due to dirofilaria repens in france and is well known in the mediterranean basin. this zoonosis can be misdiagnosed in northern areas of france. we present and discuss two human cases diagnosed in abbeville and amiens (picardy) by histological examination.200211859696
[a case of dirofilaria repens helminthiasis under the conjunctiva]. 200211898366
dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin.therapy of canine dirofilariois due to dirofilaria repens is indicated for dogs suffering from clinical signs of this disease, such as dermal swelling, sub-cutaneous nodules and pruritus. it is also important in order to decrease the risk of infection to other dogs and humans in the vicinity of the infected animal when suitable mosquito vectors are present. combined therapy with the arsenic adulticide melarsomine and the avermectin microfilaricidal doramectin was effective in clearing infection ...200211900931
dermatitis associated with dirofilaria (nochtiella) repens microfilariae in dogs from central italy.pruritic dermatitis associated with dirofilaria (nochtiella) repens microfilariae in the blood was diagnosed in 22 dogs from fermo (central italy). according to the history, previous unsuccessful treatments with corticosteroids, antibiotics, restricted diet, flea control, levamisole and ivermectin were recorded in 17 dogs (77.3%). the combined filtration tests and antigen tests, performed during the study, were negative for dirofilaria immitis and acanthocheilonema reconditum in each case. derma ...200212061238
subconjunctival infection with dirofilaria repens.cases of zoonotic dirofilariasis infection, caused by dirofilaria repens, occur widely throughout european, african, middle eastern, and asian countries. the reports of this infection in humans in india are limited, and we herein report the case of a 23-year-old man who presented with subconjunctival swelling in the right eye with no local symptoms. a large nematode was visualized on examination and the intact worm was surgically removed. the parasite was identified as a male d. repens.200212082307
genotypic assignment of infection by dirofilaria repens.dirofilariasis is a parasitic disease, which if treated inappropriately due to misdiagnosis, can cause unwanted complications particularly when the infection is located in the breast. the numerous obstacles that can cause misdiagnosis of dirofilariases by standard morphological procedures prompted the development of a dirofilaria repens-specific direct polymerase chain reaction (pcr)-based diagnostic approach using freshly infected dog blood. reliable amplification of nematode dna from formalin- ...200212113754
dirofilaria repens presenting as a premasseteric nodule.dirofilariasis is a rare zoonosis that is mainly seen with subcutaneous or pulmonary involvement. natural hosts are dogs, cats, jackals, and raccoons; however, humans can rarely become an accidental host for the parasite. in the reported case, infection manifested as a subcutaneous nodule, representing a significant diagnostic challenge for both the surgeon and the pathologist. a case of a 62-year-old man with a premasseteric soft tissue mass caused by dirofilaria repens is presented with histop ...200212221389
human subcutaneous dirofilariasis: a report of three cases manifesting as breast or axillary nodules.human subcutaneous dirofilariasis is a rare infection caused by filarial worms of the genus dirofilaria. the parasites are transmitted to man by zooanthropophilic bloodsucking insects and the infection is manifested as subcutaneous nodules. excisional biopsy is both diagnostic and therapeutic. we herein report three cases of human subcutaneous dirofilariasis diagnosed, over a period of ten years (1991-2000), in north east greece. the patients, two women and one man, were all adults between 32 an ...200212235915
cutaneous lesions in dogs with dirofilaria (nochtiella) repens infestation and concurrent tick-borne transmitted diseases.a pruritic dermatitis characterized by the presence of erythema, papules, focal or multifocal alopecia, crusting and nodules was seen in 28 dogs with dirofilaria repens microfilariae infestation in an endemic area in north-west italy. previous unsuccessful nonspecific antipruritic treatments, flea control and restricted diet were recorded in 53.6% of the patients. both the knott and the antigen tests were negative for dirofilaria immitis and acanthocheilonema reconditum. concurrent babesiosis an ...200212358611
human dirofilariasis in italy: a new case in the spermatic cord.a new case of human dirofilariasis associated with dirofilaria (nochtiella) repens (nematoda, filarioidea, onchocercidae) located in the spermatic cord is reported in a 71-year-old man from the province of campobasso (central italy). when clinical signs pointed to a testicular tumor, a monolateral orchifuniculectomy was performed. according to the scientific literature, this case appears to be exceptional in its location, being only the eighth such case recorded in the world until now. the nemat ...200212404815
dermatitis associated with dirofilaria repens microfilariae in a dog in dubai. 200212509080
systematic review of the distribution of the major vector-borne parasitic infections in dogs and cats in europe.on the basis of a systematic review of the literature, this paper provides the first evidence-based maps of the distribution of the major vector-borne parasitic infections of dogs and cats in europe. from an initial survey of 894 publications, data from 268 were analysed, summarised and collated. prevalence data were used to calculate the force of infection to provide distribution and incidence maps for canine infections with leishmania infantum, dirofilaria immitis, dirofilaria repens, babesia ...200312572938
dermatitis associated with dirofilaria repens microfilariae in a dog from rome. 200312573609
dermatitis associated with dirofilaria repens microfilariae in three dogs in saudi arabia.the presence of microfilariae of the zoonotic nematode dirofilaria repens is reported in three dogs from saudi arabia, manifesting as pruritic dermatitis with signs including erythema, alopecia, papules, crusting and hyperkeratosis. all dogs were found to have concurrent babesiosis. specific treatments against the two conditions led to complete clinical recovery and disappearance of microfilariae from the blood one month later.200312653329
[migrating subcutaneous swellings due to dirofilariasis after a visit to the south of france].in two women, aged 59 and 31 years, who suffered from an itching cutaneous nodule, subcutaneous dirofilariasis was diagnosed. the disease is characterised by recurrent migrating subcutaneous nodules and swellings. both patients recently visited the south of france. laboratory examination revealed a moderate eosinophilia. in both patients, filaria antibodies were demonstrated during the course of the disease and a nodule was eventually resected. parasitological examination revealed dirofilaria re ...200312693088
intra-oral dirofilaria repens infection: report of seven cases.cutaneous dirofilariasis usually affects animals such as cats and dogs which are known to be the natural host of dirofilaria. dirofilariasis displays a worldwide distribution. certain geographic regions account for the majority of reported cases. south-eastern united states, australia and europe have been identified as endemic regions (1, 2). however, new endemic areas are arising with increased awareness in african and asian regions. out of about 40 different species of dirofilaria only a few s ...200312901735
orbital swelling as a sign of live dirophilaria repens in subconjunctival tissue.this report presents a case of live dirophilaria found in the subconjunctival space in a woman, in whom the main symptoms were swelling of the orbital tissue. after subconjunctival anaesthesia the dirophilaria were removed surgically. a histopathological examination revealed an adult, non-gravid female dirofilaria repens s. acutiuscula. to the authors' knowledge this is the first case of subconjunctival live dirophilaria reported in a human.200312953965
the identification and estimation of acetylcholine in three parasitic nematodes (ascaris lumbricoides, litomosoides carinii, and the microfilariae of dirofilaria repens). 195513280270
[dirofilaria repens under the conjunctiva]. 195713492921
susceptibility of aedes albopictus to dirofilaria repens infection in cats. 196113727536
[distribution of dirofilaria repens in the kazakhstan]. 195913849357
studies on the in vitro action of potassium permanganate on the adult worms of dirofilaria immitis, microfilariae of dirofilaria repens and dirofilaria immitis and of hydrogen peroxide on the adult worms of litomosoides carinii. 196113913315
a note on the absence of action of hetrazan and alvo-sulphone (dds) on the microfilariae of dirofilaria repens in dog and the developing forms in the mosquito. 196213913318
larval development of brugia ceylonensis jayewardene, 1962, in aedes aegypti, with a brief comparison of the infective larva with those of brugia spp., dirofilaria repens and artionema digitata. 196314077666
on the second case of human infection with dirofilaria (nochtiella) repens from ceylon. 196414250815
experimental maintenance of dirofilaria repens and d. immitis in dogs. 195514365779
[human dirofilariasis in the moscow region].dirofilaria repens railliet et henry, 1911 was for the first time studied in the moscow region where 11 patients (6 males and 5 females) aged 4-72 years were recorded in 2000-2002. the geographical distribution (the southern and south-eastern parts of the region) of local cases of dirofiliriasis, was observed. there was a relatively high rate of d. repens in the male genitalia of the infected patients as compared with that reported by other authors. in accordance with the current terminology, d. ...200314564848
retrospective study on the presence and pathogenicity of dirofilaria repens in 5 dogs and 1 cat from aosta vally.aosta valley is the only region of italy free of reported human cases of dirofilariosis due to dirofilaria repens. nonetheless, the retrospective analysis of five locally acquired d. repens infections in dogs, seems to indicate that an animal reservoir exist in the area. a feline case imported from camargue, france, is also described. the most common dermatological signs were erythema, alopecia, crusting, papulae and nodules. all patients had lesional pruritus and dogs were affected by concurren ...200314593932
first finding of dirofilaria repens in a natural population of aedes albopictus.the invasive mosquito aedes albopictus (skuse) (diptera: culicidae) has become widespread in italy during the past decade. also italy has foci of canine filariasis caused by dirofilaria (spirurida: onchocercidae), due to subcutaneous d. repens railliet & henry as well as the dog heartworm d. immitis (leidy) transmitted by various vector mosquitoes (diptera: culicidae). in 2002, at fiumicino, west of rome (lazio region), 17% of dogs were found to have d. repens microfilariae in peripheral blood. ...200314651660
management of subconjunctival dirofilaria repens. 200415006869
subcutaneous dirofilaria repens infection of the eyelid in serbia and montenegro. 200415224588
critical review of the vector status of aedes albopictus.the mosquito aedes (stegomyia) albopictus (skuse) (diptera: culicidae), originally indigenous to south-east asia, islands of the western pacific and indian ocean, has spread during recent decades to africa, the mid-east, europe and the americas (north and south) after extending its range eastwards across pacific islands during the early 20th century. the majority of introductions are apparently due to transportation of dormant eggs in tyres. among public health authorities in the newly infested ...200415347388
efficacy of long-term monthly administration of ivermectin on the progress of naturally acquired heartworm infections in dogs.this study was designed to evaluate the efficacy of prolonged monthly ivermectin treatment against dirofilaria immitis in client-owned dogs with naturally acquired infections and to clinically monitor the animal's response to the slow killing of heartworms, with death of the worms distributed over a period of up to 2 years. a total of 17 male and female dogs of different breeds and ages were used. prior to treatment, all of the dogs tested positive for heartworm antigen (ag) and all but two had ...200415381305
comparison of the acid-phosphatase staining and polymerase chain reaction for detection of dirofilaria repens infection in dogs in korea.this study was performed to compare acid-phosphatase staining with polymerase chain reaction (pcr) analysis for the diagnosis of dirofilaria repens infection. the infection of d. repens was confirmed in korean reared german shepherd dogs. knott's tests were carried out for the detection of microfilaria in 543 korean reared german shepherd dogs (255 females and 288 males). eighty four of the 543 dogs (15.5%) showed microfilaria-positive reactions with the modified knott's test, and the test-posit ...200415472472
subcutaneous dirofilariasis caused by dirofilaria repens.human dirofilariasis caused by dirofilaria repens d. repens is a common zoonosis in the mediterranean countries and parts of south asia. during the last decade, it has been reported from countries previously considered non-endemic. this is likely due to the increased awareness regarding dirofilaria infection. in some such cases however, dirofilariasis correlated with the travel of the patient to the endemic areas. we present the case of a saudi male who had d. repens infection in the subcutaneou ...200415573204
adult dirofilaria repens nematodes in a cat from kiev, ukraine. 200415573788
[subcutaneous dirofilariasis due to dirofilaria repens in tunisia: a case involving the scrotum].dirofilariasis is a rare anthroponotic disease encountered only in the old world with most cases having been reported from italy. the dog is the reservoir of this parasite. man is accidentally infected by mosquitoes. we report the case involving a 27-year-old man living in a rural region of northern tunisia who presented with a subcutaneous abscess-like scrotal nodule. microscopic examination of the surgical specimen unexpectedly revealed parasitic involvement. morphologic examination led to dia ...200415615391
unusual finding in a nipple discharge of a female dog: dirofilariasis of the breast.we report a case of dirofilariasis of the breast occurring in a 6-yr-old bernese female dog living in central italy presenting with a breast lump, diagnosed on cytological examination of nipple secretion fluid smears. the direct smears of nipple discharge revealed clusters of glandular cells characterized by mild pleomorphic appearance and the presence of some nematodes of about 350 microm in length in the background. the smears also contained several inflammatory cells, including eosinophils. b ...200515637669
subcutaneous tumor of the lower eyelid: a potential manifestation of a dirofilaria repens infection.to report a case of dirofilaria repens presenting as a subcutaneous tumor of the lower eyelid.200515751252
[dirofilariasis in the autonomous republic of crimea].the paper presents data on the prevalence of dirofilariasis in the autonomous republic of crimea during 5 years from 1999 to 2003. the nematode dirofilaria repens is a causative agent of the disease. sporadic cases of helminthiasis are annually registered in some urban and rural areas on the plain of the peninsula. the disease is absent on the foothills and black sea coast of the southern and eastern parts of crimea. the localization of the parasite is typical of this helminthiasis. dirofilarias ...200515801224
[two new human cases of dirofilariasis in sardinia].two new human cases of dirofilariasis, both due to dirofilaria (nochtiella) repens, recently occurring in nuoro province (sardinia) on people permanently resident in the island, are described. the parasite was located in one case into the uterine round ligament, in the other it was subconjunctival. some observations about the diagnostic difficulties in the first one and the dramatic symptoms in the second, whose parasite was yet alive during the surgical ablaction, are discussed. these cases are ...200415828433
dirofilariosis in dogs and humans in kerala.there has been an increased occurrence of filarial worms in the subcutaneous tissues and subconjunctival space of human beings belonging to different areas of the state of kerala. the present work was carried out to identify the worms recovered from human cases, to study the presence of microfilariae in dogs and to discuss the possible mode of infection in human beings. twelve worm specimens from human patients received in the department of veterinary parasitology, college of veterinary and anim ...200515937374
a case of palpebral dirofilariasis.dirofilaria repens infection is the most frequent and widespread dirofilariasis in the world. in italy subcutaneous dirofilariasis is present especially in northern-central areas.200515945012
crusted papule on forehead due to dirofilaria repens. 200516105353
study of dirofilariasis in a selected area in the western province.human dirofilariasis is a zoonotic infection caused by the filarial worm, dirofilaria (nochtiella) repens, whose primary host is the dog. this infection is on the increase over the past decade in sri lanka and the prevalence of canine dirofilariasis in the country is also believed to be high. we present here a study on public awareness of dirofilariasis and the prevalence of this infection in dogs in negombo, an urban area that has a high domestic canine population.200516114770
an unusual parasitological finding in a subcutaneous mammary nodule.while examining some histological sections of a clinically suspected neoplastic nodule in a woman's breast, sections of dirofilaria repens were noted in the same nodule along with sections of a different nematode. the latter appeared to be a specimen possibly belonging to the genus anatrichosoma (family trichosomoididae), a parasitic group of helminths rarely reported in humans. in view of the diagnostic interest in an exceptional event, such as a double parasitic infection in the same nodule, w ...200516136755
dog filariosis in the lazio region (central italy): first report on the presence of dirofilaria repens.epidemiological investigations were carried out in the lazio region to assess the status of canine filariosis and to evaluate the actual risk for veterinary and medical public health.200516185352
what is happening outside north america regarding human dirofilariasis?the etiologic agents of human dirofilariasis in the old world are dirofilaria immitis, which cause pulmonary and subcutaneous nodules, and dirofilaria repens, which cause ocular lesions. although reports of new cases of dirofilariasis are sporadic in other parts of the world, a considerable amount of information is generated in europe regarding human dirofilariasis. most cases have been detected in the mediterranean countries, ukraine, and russia; however, isolated or short series of cases have ...200516198821
[human subconjunctival dirofilariasis: two tunisian case studies].two new cases of human subconjunctival dirofilariasis are reported in tunisia. dirofilaria immitis was identified in the first case and dirofilaria repens in the second. diagnosis was made by histological examination of excised nodules. we note that the patients are young (8 and 10 years, respectively) and that cases of human dirofilariasis caused by dirofilaria immitis are present in tunisia.200516208214
subtenons infection by dirofilaria repens.zoonotic filariasis caused by dirofilaria repens, a parasite of carnivores occurs mainly in countries surrounding mediterranean region. the infection occurs in and around eye among animal handlers through vector transmission. we are reporting a case of human dirofilariasis affecting subtenons region in a 63 year-old woman from coimbatore, south india. the purpose of this article is to review the clinical course and management of ocular dirofilariasis.200616505560
[conjunctival dirofilariasis due to dirofilaria repens. a new tunisian case].dirofilariasis due to dirofilaria repens is a parasitic disease affecting domestic animals and transmitted to man by mosquito bites. human infestation is rare and involves benign subcutaneous and ocular manifestations. the diagnosis is made by excisional biopsy, which is also the sole recommended treatment. there are few reports of human infection in tunisia.200616523151
intravitreal dirofilariasis: a rare ocular infection.human ocular dirofilariasis is a zoonotic disease, rare in europe, caused by filarial nematodes. the parasite is either encysted in a subcutaneous nodule or located under the bulbar conjunctiva. we report the case of a 62-year-old man with intravitreal dirofilariasis, which is a rare site of presentation of the nematode in the human eye. it was located in the fundus area and was surgically removed. the nematode was identified as dirofilaria repens (d. conjuctiva) by two different microbiology de ...200616527779
subconjunctival infection with dirofilaria repens. 200616544743
dirofilaria repens: a dog parasite presenting as a paranasal subcutaneous nodule. 200616650184
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