| nucleic acid homology studies of adenovirus type 7-sv40 interactions. | | 1966 | 4287386 |
| mixed infection of african green monkey kidney cells by adenovirus 7 and sv 40. | | 1965 | 4288171 |
| induction of neoplasia in vitro in hamster thyroid tissue by sv40 and adenovirus 7-sv40 "hybrid" (strain lle46). | | 1966 | 4288638 |
| inactivation and density studies with para-adenovirus 7 (sv40-adenovirus "hybrid" population). | | 1966 | 4289224 |
| biophysical evidence for linkage of adenovirus and sv40 dna's in adenovirus 7-sv40 hybrid particles. | | 1966 | 4291405 |
| variation in the oncogenic potential of human adenoviruses carrying a defective sv40 genome (para). | the acquisition of the defective sv40 genome by a variety of human adenovirus serotypes by the process of transcapsidation has resulted in the addition of oncogenic potential for newborn hamsters to the previously nononcogenic adenovirus types 1, 2, 5, and 6. these serotypes have previously been grouped together by the high gc content of their dna. transcapsidation of the sv40 genome to weakly oncogenic adenovirus types 3, 14, 16, and 21 has failed to increase their oncogenic potential although ... | 1968 | 4294682 |
| studies on the mechanism of enhancement of adenovirus 7 infection in african green monkey cells by simian virus 40: formation of adenovirus-specific rna. | | 1968 | 4295919 |
| neonatal infection caused by adenovirus type 7. | | 1968 | 4296691 |
| solubilization and some properties of the erythrocyte receptor for adenovirus type 7 haemagglutinin. | | 1969 | 4304487 |
| [fatal infection with adenovirus type 7. some immunological aspects]. | | 1968 | 4304546 |
| variation in properties of plaque progeny of para (defective simian papovavirus 40)-adenovirus 7. | one hundred and twelve progeny from double plaque-purified clones were derived from the original para (defective simian papovavirus 40)-adenovirus 7 population. these progeny were found to differ in their oncogenic potential in newborn hamsters with progeny from 20 clones not inducing any tumors during 1 year of observation. the varying tumorigenicity of the individual clonal progeny was not related to the titer of para (particle aiding replication of adenovirus) in the inoculum. there was a per ... | 1969 | 4311794 |
| variants of defective simian papovavirus 40 (para) characterized by cytoplasmic localization of simian papovavirus 40 tumor antigen. | three isolates of para (particle aiding replication of adenovirus)-adenovirus 7 out of a total of 112 clonal progeny derived by two successive plaque purifications in green monkey kidney cells (gmk) were found to induce the synthesis of simian papovavirus40 (sv 40) tumor (t) antigen in the cytoplasm of infected cells. the variant viruses induced plaque formation in human embryonic kidney cells which followed one-hit kinetics. in gmk cells, plaque formation followed two-hit kinetics which convert ... | 1969 | 4311795 |
| encephaloningitis in children associated with an adenovirus type 7 epidemic. | | 1970 | 4315516 |
| quantitative characteristics of the transformation of hamster cells by para (defective simian virus 40)-adenovirus 7. | an in vitro method for the quantitative measurement of transformation in hamster embryo fibroblasts by the para [defective simian virus 40 (sv40)]-adenovirus 7 hybrid has been developed. transformation by para particles followed one-hit kinetics with a ratio of 1 focus-forming unit per 250 plaque-forming units. the method of viral adsorption had a direct effect upon the total number of foci which developed but not on the quantitative aspects of this assay. a fluorescent-focus assay was developed ... | 1970 | 4315956 |
| transformation of african green monkey kidney cells by irradiated adenovirus 7-simian virus 40 hybrid. | the ability of adenovirus 7-simian virus 40 (sv40) hybrid (strain ll "e-46") to replicate decreased exponentially as a function of the amount of gamma-irradiation; the ability to induce sv40 and adenovirus 7 t antigen decreased at a much slower rate. nevertheless, the virus was still able to transform african green monkey kidney cells at a radiation dosage that had completely destroyed its replication ability. all transformed colonies were positive for sv40 t antigen but were negative for adenov ... | 1968 | 4316019 |
| characterization of the strain of adenovirus type 7 carrying the defective monkey cell-adapting component. | the strain of adenovirus type 7 carrying the defective monkey cell-adapting component (mac) has been further characterized. mac is more sensitive to inactivation by ultraviolet light than the associated adenovirus, which, in turn, is more rapidly inactivated than complete simian virus 40 (sv40). the 37% dose was 16 sec for mac, 60 sec for adenovirus, and 84 sec for sv40. filtration through membranes revealed that both mac and adenovirus were retained by 100-mmu filters. mac equilibrated in cesiu ... | 1967 | 4316236 |
| transformation of simian virus 40-resistant hamster cells with an adenovirus 7-simian virus 40 hybrid. | when the hamster cell lines bhk21 and nil-2 were infected at a multiplicity of 100 with the adenovirus 7-simian virus 40 (sv40) hybrid (strain lle46), sv40 t antigen was induced in 0.1 to 6% of the cells during the first 96 hr postinfection, morphological changes occurred 3 to 7 weeks later, and eventually all the cells contained sv40 t antigen, but no adeno 7 t antigen. results were similar when primary and secondary monolayer cultures of hamster embryo (he) cells were infected with the adeno 7 ... | 1967 | 4316243 |
| severe illnesses due to adenovirus type 7 in children. | | 1969 | 4318009 |
| transformation of hamster cells by variants of para-adenovirus 7 able to induce sv40 tumor antigen in the cytoplasm. | | 1970 | 4318984 |
| [adenovirus 7 endemo-epidemic in a training center for naval recruits. (results of a 12 month study)]. | | 1969 | 4321191 |
| an epidemic of adenovirus type-7 bronchopneumonia in bantu children. | | 1971 | 4322988 |
| the histopathology of tumors induced by para-adenovirus 7 transformed cell clones. | | 1970 | 4323387 |
| simian virus 40 integration site in an adenovirus 7-simian virus 40 hybrid dna molecule. | the e46(+) strain of adenovirus 7 is a mixed-virus population containing defective adenoviurs 7-sv40 hybrid particles and helper, nonhybrid adenovirus 7 particles. we have applied electron microscopic mapping techniques to obtain a physical map of the genome of the hybrid particles present in e46(+)pl1, a substrain of e46(+) derived from a single two-hit plaque. dna molecules extracted from purified e46(+)pl1 virions were found to be linear duplexes, with a mean lenght of 10.9 mum. when these mo ... | 1971 | 4324999 |
| components of adenovirus-simian virus 40 hybrid viruses. | the dna and protein components of the adenovirus 7-simian virus (sv)40 hybrid virus "e46(+)" have been investigated. the ad.7-sv40 hybrid dna genome could be distinguished from nonhybrid ad. 7 genome on the basis of its molecular weight in an alkaline sucrose gradient. the hybrid genome could also be separated from nonhybrid adenovirus 2 dna when purified transcapsidant adenovirus 2(+t7) (ad.7-sv40 dna within an ad.2 capsid) was studied. the presence and amount of sv40 dna in the hybrid virus ge ... | 1971 | 4327006 |
| adenovirus type 7--associated encephalitis. | | 1970 | 4329176 |
| immunization with live types 7 and 4 adenovirus vaccines. i. safety, infectivity, antigenicity, and potency of adenovirus type 7 vaccine in humans. | | 1971 | 4330997 |
| immunization with live types 7 and 4 adenovirus vaccines. ii. antibody response and protective effect against acute respiratory disease due to adenovirus type 7. | | 1971 | 4330998 |
| variation in oncogenic and transforming potential of para (defective sv40)-adenovirus 7. | | 1972 | 4335076 |
| fatal pneumonia associated with adenovirus type 7 in three military trainees. | | 1972 | 4337012 |
| [characterization of a cell strain derived from a hamster tumor induced with the hybrid para-adenovirus 7]. | | 1971 | 4341043 |
| synthesis of viral ribonucleic acid during restricted adenovirus infection. | the mechanism by which simian virus 40 converts the abortive adenovirus type 7 infection of monkey cells into an efficient lytic infection has been investigated. analysis of ribonucleic acid (rna) synthesis during unenhanced and enhanced infection of monkey cells has shown that adenovirus rna synthesized in the abortive infection contains both "early" and "late" sequences. in hybridization competition experiments, early adenovirus rna from human cells prevented the hybridization of only 20% of t ... | 1972 | 4342240 |
| quantitative transformation of primate cells by para (defective sv40)-adenovirus type 7. | | 1972 | 4344149 |
| nasal secretion protein responses in patients with wild-type adenovirus disease. | proteins were studied in nasal secretions obtained from marine corps trainees infected with wild adenovirus type 7 both during the acute phase of illness and after recovery. illness was associated with a marked increase in the concentration of serum proteins in the secretions, and during inflammation there was no apparent barrier to the passage of large molecules (molecular weight 775,000) from the serum into the respiratory passages. at the time of virus isolation, trainees requiring hospitaliz ... | 1972 | 4344395 |
| prevention of simian virus 40 tumors by hamster fetal tissue: influence of parity status of donor females on immunogenicity of fetal tissue and on immune cell cytotoxicity. | fetal tissue from primiparous hamsters prevented simian virus 40 (sv40) tumorigenesis in male hamsters, whereas fetal tissue from multiparous hamsters did not. the parity status of normal (uninoculated) hamsters also influenced the cytotoxicity of their lymphoid cells against tumor cells. lymph node cells from nonpregnant primiparous and multiparous animals were cytotoxic in microcytotoxicity tests against sv40, polyoma, and adenovirus 7 tumor cells, but were not active against control bhk cells ... | 1973 | 4346032 |
| an outbreak of adenovirus type 7 infection in children in montreal. | thirteen infants and children with adenovirus type 7 infection proved by virus isolation are described. high fever, cough and dyspnea were the most frequent findings; in infants under 1 year of age wheezing was common. four patients required artificial ventilation. lobar collapse, consolidation and hyperinflation were frequent radiologic findings. none of the symptoms responded to antibiotic therapy or bronchodilator drugs. three patients died (mortality rate of 23%). pathologic findings were co ... | 1973 | 4347082 |
| pneumonia and massive pleural effusion associated with adenovirus type 7. | | 1973 | 4353074 |
| fever and petechiae with adenovirus type 7 infection. | | 1974 | 4359803 |
| epidemic of adenovirus type 7 acute conjunctivitis in swimmers. | | 1974 | 4360768 |
| membranous conjunctivitis due to adenovirus type 7 infection. | | 1974 | 4360848 |
| specific fragmentation of dna of adenovirus serotypes 3, 5, 7, and 12, and adeno-simian virus 40 hybrid virus ad2+nd1 by restriction endonuclease r.ecori. | the products of complete digestion of duplex dna of each of seven human adenoviruses with restriction endonuclease r. ecori ranged from two fragments for adenovirus 7 dna (ad7) to six fragments for ad12 and ad2 dna. viral serotypes from the same subgroups appeared to have related cleavage sites; ad3 dna and ad7 (cl e46-ll) dna were each cleaved into three fragments, and ad7 (cl 19) dna lacked one of the cleavage sites present in ad3 and ad7 (cl e46-ll) dna. one of the cleavage sites in ad2 dna w ... | 1974 | 4365324 |
| biological and biophysical characterization of sv40 cytoplasmic t-antigen-inducing mutants of para-adenovirus 7. | | 1973 | 4367381 |
| [study of the expression of neoplasm transplantation antigens and s antigens in hamster cells, transformed by para-adenovirus 7]. | | 1974 | 4375482 |
| fatal pneumonia associated with adenovirus type 7. | | 1967 | 4378107 |
| adenovirus type 7 outbreak in a kindergarten. | | 1965 | 4378168 |
| plaque formation by adenovirus 7 in human diploid cell strains. | | 1969 | 4389114 |
| detection of viral dna sequences in adenovirus-transformed cells by in situ hybridization. | cytological preparations of cells transformed by members of three groups of human adenoviruses, adenovirus 12, 7, and 2, were annealed with radioactive complementary rna (crna) (4 x 10(7) to 4.5 x 10(7) dpm/mug) prepared by copying viral dna with the escherichia coli dna-directed rna polymerase. these in situ hybridizations detected adenovirus-specific dna sequences in interphase nuclei when transformed cells were annealed with homologous viral crna, but not with heterologous viral crna. the hig ... | 1973 | 4586775 |
| [properties of the intralysosomial virus at the beginning of adenovirus 7 penetration in hela cells]. | | 1972 | 4626116 |
| demonstration of intranuclear t-antigen by antisera to purified adenovirus 7. | | 1969 | 4899206 |
| immunofluorescence of adenovirus type 7 t-antigen(s) and virion antigens in infected kb cells. | | 1970 | 4914466 |
| replication of adenovirus type 7 in monkey cells: a new determinant and its transfer to adenovirus type 2. | a strain of human adenovirus type 7, adapted to replication in green-monkey kidney cells, requires the interaction of two particles to initiate plaque formation in the simian cells. one particle is a true adenovirion. the second, apparently defective, consists of a genome carrying amonkey-adapting component in an adenovirus capsid; this genome does not express known sv40 determinants. the addition of human adenovirus type 7 that is not adapted enhances the titer and changesconditions for plaque ... | 1966 | 4958853 |
| oncogenic simian adenoviruses. v. recovery of infectious virus from intracranial tumor cells induced by simian adenovirus 7. | | 1969 | 4978896 |
| pathogenesis of oncogenic simian adenoviruses. 8. the histopathology and ultrastructure of simian adenovirus 7-induced intracranial neoplasms. | | 1970 | 4987496 |
| disruption of adenovirus type 7 by lithium iodide resulting in the release of viral deoxyribonucleic acid. | adenovirus type 7 exposed to solutions of lii was progressively converted into slower sedimenting deoxyribonucleic acid (dna)-containing particles, and, ultimately, under proper conditions, dna free or almost free from protein was released from the virus. the degree of viral degradation was dependent on the time of treatment, on the temperature, and on the concentration of the reagent. | 1970 | 4988267 |
| partial characterization of the complementary sites involved in the reaction between adenovirus type 7 and erythrocyte receptors. | | 1970 | 4991707 |
| the fate of adenovirus type 7 deosyribonucleic acid during treatment of the virus with formamide. | | 1970 | 5501756 |
| adenovirus type-7 t antigen: separation from hexon antigen by gel filtration. a preliminary report. | | 1968 | 5644206 |
| two-dimensional immuno-osmophoresis of adenovirus type 7 antigens. | a test is described in which adenovirus type 7 antigens are separated by two successive perpendicular applications of electrophoresis through agar, causing precipitin formation with cationic immune globulins. three bands produced by adenovirus cultures distinguish among hexon, fiber, and penton antigens. | 1969 | 5772395 |
| construction and characterization of an sv40 mutant defective in nuclear transport of t antigen. | an sv40-adenovirus 7 hybrid virus, para(ct), has been described that is defective for the nuclear transport of sv40 large tumor antigen. an sv40(ct) mutant was constructed using sv40 early and late region dna fragments derived from para(ct) and wild-type sv40 respectively. the sv40(ct)-3 construct is defective for viral replication, but can be propagated in cos-1 cells. t antigen induced by sv40(ct)-3 is localized in the cytoplasm of infected cells. the ct mutation also inhibits the transport of ... | 1984 | 6086146 |
| restriction analysis and homology studies of the bovine adenovirus 7 genome. | we located the cleavage sites for restriction endonucleases ecori, hindiii, and bamhi on the genome of bovine adenovirus 7. cross-hybridization at reduced stringency revealed two regions of homology shared by the dna of human adenovirus 2 and bovine adenoviruses 7 and 3. these regions correspond to the hexon and the iva2 protein genes of the human adenovirus. another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide iiia ... | 1984 | 6088811 |
| factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. | adenoviruses are well known causes of respiratory illness in children. long term sequelae reported with types 3, 7, and 21 include bronchiolitis obliterans, bronchiectasis, and the hyperlucent lung or mcleod syndrome. twenty children admitted to hospital with adenovirus type 7 pneumonia between 1960 and 1978 were studied and compared with 20 controls admitted during the same period with adenovirus type 7 upper respiratory tract infections. sixty five per cent of the pneumonia group had developed ... | 1984 | 6093715 |
| induction of delta 3(4) ketosteroid synthesis by interferon in mouse adrenal tumour cell cultures. | interferon, like cholera toxin, induces in mouse adrenal yi cells the production of delta 3(4) ketosteroids. in parallel, cyclic amp (camp) is activated. at high concentrations, mouse but not human interferon induces a cell rounding effect, similar to that obtained with cholera toxin. in yi cells transformed by simian adenovirus 7, production of camp is still increased by that of steroids is blocked. the role if interferon in these cellular events is discussed. | 1980 | 6161994 |
| [oligopeptide analysis of the hexons of human adenovirus types 1, 2 and 6 and simian adenovirus sa7]. | a comparative analysis of hexons of human adenovirus (hadv) types 1, 2, 6 and simian adenovirus type 7 (sa7) was carried out by peptide mapping. common and unique peptides were found in hexons from virions of human adenovirus types 2 and 6 and sa7. the similarity of hexons of hadv types 2 and 6 was shown to be more marked than hadv and sa7 hexons. similar data were obtained in the analysis of excessively synthesized (soluble) hexons of hadv types 1 and 6 and sa7. a significant homology between ... | 1981 | 6175108 |
| antiviral effects of bovine interferons on bovine respiratory tract viruses. | the antiviral effects of bovine interferons on the replication of bovine respiratory tract viruses were studied. bovine turbinate monolayer cultures were treated with bovine interferons and challenged with several bovine herpesvirus 1 strains, bovine viral diarrhea virus, parainfluenza type 3 virus, goat respiratory syncytial virus, bovine respiratory syncytial virus, bovine adenovirus type 7, or vesicular stomatitis virus. treatment with bovine interferons reduced viral yield for each of these ... | 1984 | 6201505 |
| a seroepidemiologic survey of three pronghorn (antilocapra americana) populations in southeastern idaho, 1975-1977. | sera from 104 adult and 42 fawn pronghorn antelope (antilocapra americana) from southeastern idaho were tested against selected livestock pathogens. the numbers positive/numbers tested (% positive) were as follows: bovine virus diarrhea - adults 2/102 (2), fawns 0/41 (0);; infectious bovine rhinotracheitis - adults 27/101 (27), fawns 9/42 (22); parainfluenza 3 - adults 79/104 (76), fawns 22/42 (52); bovine adenovirus 7 - adults 42/103 (41), fawns 20/48 (48); bovine adenovirus 3 - adults 11/32 (3 ... | 1980 | 6246285 |
| the nucleotide sequence of the transforming bglii-h fragment of adenovirus type 7 dna. | the nucleotide sequence of the leftmost bglii-h fragment (0--4.5%) of weakly oncogenic human adenovirus serotype 7 (ad7) has been determined (1568 base pairs). this is the shortest ad7 dna fragment reported to transform primary rat cells into an immortal cell line (dijkema et al., 1979). the l-strand of bhlii-h was found to contain the complete information for a polypeptide of at most 28 051 daltons, followed by the putative promoter site of the next gene. comparison of the determined ad7 sequen ... | 1980 | 6247243 |
| [cloning simian adenovirus 7 dna fragments in escherichia coli bacteria using plasmid vector pbr322]. | | 1980 | 6252003 |
| inhibition of nuclear migration of wild-type sv40 tumor antigen by a transport-defective mutant of sv40-adenovirus 7 hybrid virus. | | 1980 | 6252682 |
| biochemical characterization of nuclear and cytoplasmic forms of sv40 tumor antigens encoded by parental and transport-detective mutant sv40-adenovirus 7 hybrid viruses. | | 1980 | 6252683 |
| unique species of mrna from adenovirus type 7 early region 1 in cells transformed by adenovirus type 7 dna fragment. | adenovirus type 7 (ad7) early region 1 mrna species transcribed in rat cell lines transformed by the hindiii-i . j fragment (the left 7.8% of the viral genome) and in human kb cells infected with ad7 were mapped on the viral genome, using s1 nuclease gel and diazobenzyloxymethyl paper hybridization techniques. at the early stage of productive infection, two mrna's (950 and 840 nucleotides long) with the common 5' and 3' ends but different internal splicings were mapped from region 1a (map units ... | 1980 | 6253660 |
| epidemic outbreaks of adenovirus 7 with special reference to the pathogenicity of adenovirus genome type 7b. | adenovirus type 7 (ad 7) is the serotype among the 36 recognized adenovirus types which most frequently has been associated with severe illness. three different epidemic patterns of ad 7 infection can be distinguished: 1) the first appears during the winter among infants with median age below two years, has characteristic symptoms of high fever and pneumonia and an outcome that may be fatal: 2) the second appears in the fall among children with median age seven years, has characteristic symptoms ... | 1980 | 6254358 |
| [cloning of fragments of simian adenovirus 7 dna in escherichia coli bacteria using plasmid vector pbr322]. | | 1980 | 6254743 |
| properties of simian adenovirus 7 after one single passage in simian marmoset lymphoblastoid cells transformed by epstein barr virus. | simian adenovirus 7 gave an abortive infection in simian marmoset lymphoblastoid cells, b 95-8 and m 81 (transformed by epstein barr virus) whereas non transformed simian lymphocytes could not replicate this virus. electron dense incomplete particles with a lower density than standard virus in cscl gradients were isolated. virus yields were low and the percentage of cells containing viral antigen as measured by immunofluorescence was 0.01% for b 95-8 cells and still less for the m 81 cells. afte ... | 1980 | 6256015 |
| virus infection of endothelial cells. | endothelial injury is important in the pathogenesis of thrombosis, atherosclerosis, disseminated intravascular coagulation, and vasculitis. the ability of several common human viruses to infect cultures of endothelial cells obtained from human umbilical veins or bovine thoracic aorta was demonstrated. indicators of infection included cytopathology, viral growth curves, and antigen detection by immunofluorescence. herpes simplex virus type 1, adenovirus type 7, measles virus, and parainfluenza vi ... | 1981 | 6260874 |
| subgenomic viral dna species synthesized in simian cells by human and simian adenoviruses. | dna synthesized after infection of simian tissue culture cells (bsc-1 or cv-1) with human adenovirus type 2 or 5 or with simian adenovirus 7 was characterized. it was demonstrated that as much as 40% of the virus-specific dna in nuclei of infected monkey cells consists of subgenomic pieces. no subgenomic viral dna species were detected in the nuclei of human (hela) cells infected with these adenovirus types. restriction analysis showed that these short viral dna molecules contain normal amounts ... | 1981 | 6261009 |
| prevention of primary simian adenovirus type 7 (sa7) tumors in hamsters by adoptive transfer of lymphoid cells: role of different cell types. | | 1981 | 6261538 |
| chronic lung damage caused by adenovirus type 7: a ten-year follow-up study. | twenty-seven children aged 0.6 to 7.0 (mean 2.1) years were admitted to the hospital in 1967 and 1968 with type 7 adenoviral pneumonia. all ran a prolonged course. type 7 adenovirus was isolated from 14 children, and in the other 13, the rise in the titer of complement-fixing antibodies to adenovirus was fourfold or greater. the outcome of the disease in these 27 children was reassessed in 1979, 9.6 to 12.1 (mean 10.7) years after the adenovirus type 7 pneumonia. twenty-two were examined clinica ... | 1981 | 6265156 |
| the gene for polypeptide ix of human adenovirus type 7. | this paper describes the nucleotide sequence of subgroup b human adenovirus type 7 (ad7) between positions 3351-4010, and of cloned cdna derived from mrnas encoded by this segment. one of these (mrna vii) is shown to be unspliced, and has its 5'- and 3'-ends encoded by positions 3460 (determined by the nuclease s1 technique) and 3939, respectively. the mrna sequence contains a single open reading frame for protein biosynthesis between the first available initiation triplet aug at position 3481 t ... | 1981 | 6266923 |
| molecular epidemiology of adenoviruses: alternating appearance of two different genome types of adenovirus 7 during epidemic outbreaks in europe from 1958 to 1980. | four genome types of adenovirus serotype 7 (ad7, ad7a, ad7b, and ad7c) were identified by use of dna restriction enzymes bamhi, ecori, and smai. we obtained information on the distribution of the four ad7 genome types by typing 68 ad7 isolates obtained in the netherlands from 1958 to 1979 and 36 ad7 isolates obtained in sweden from 1964 to 1980. the ad7 prototype was never detected, and only seven isolates were genome-typed ad7a. ad7b and ad7c accounted for 94% of the genome-typed isolates obtai ... | 1981 | 6273316 |
| lobar pneumonia associated with adenovirus type 7. | | 1981 | 6277442 |
| integration of foreign genome fragments into cells transformed or cotransformed with fragmented adenoviral dna. | the integration of dna of highly oncogenic simian adenovirus type 7 (sa7) and non-oncogenic human adenovirus type 6 (ad6) into the genome of newborn rat kidney cells transformed by fragmented dna preparations was studied using reassociation kinetics and spot hybridization. transforming dna was fragmented with the specific endonuclease sali (sa7) and bglii (ad6). in contrast to the cell transformation by intact viral dna, transformation by fragmented dna resulted in integration into the cellular ... | 1981 | 6277738 |
| [simian adenovirus genome. ii. identification of specific fragments of viral dna possessing transforming activity]. | the antigenic variant of simian adenovirus 7 (sa7) dna was cleaved by restriction endonucleases ecori, xbai, bamhi, sali. the resulted digests of viral dna were tested for transforming activity using the "calcium" technique. it was shown that bamhi. xbai and sali digests transformed primary baby rat kidney cells as well as native viral dna. the transforming activity of separated bamhi and sali fragments was tested also. the viral dna fragments with transforming activity (bamhi-b and sali-b) were ... | 1982 | 6280036 |
| physical mapping of human adenovirus type 7 dna using a simple and sensitive method of terminal labeling. | the tyrosine-containing peptide covalently attached to each 5'-terminus of adenovirus type 7 (ad 7; greider) dna was labeled with 125i. the 5'-labeled dna was subjected to digestion with several restriction endonucleases and the size of the labeled terminal fragments was determined. partial hydrolysis by these endonucleases generated a series of labeled fragments which were fused to the terminal fragments and could, therefore, be detected by autoradiography. from the sizes of the partial product ... | 1982 | 6290317 |
| gene organization of the transforming region of adenovirus type 7 dna. | the sequence of the leftmost 11% of the weakly oncogenic human adenovirus type 7 (ad7) dna has been determined. this part of the ad7 viral genome encompasses early region e1 which has been shown to be involved in the process of cell transformation in vitro (dijkema et al., 1979). from the nucleotide sequence and determined coordinates of the e1 mrnas, we are able to predict the primary structure of the polypeptides encoded by the transforming region of ad7. the organization of the e1 region of a ... | 1982 | 6290319 |
| hyperlucent lung: long-term complication of adenovirus type 7 pneumonia. | | 1983 | 6291737 |
| the nucleotide sequence of the gene encoding protein iva2 in human adenovirus type 7. | the nucleotide sequences of cloned dna segments encoding the iva2 gene from ad7 and a portion of ad12 (group b and group a human adenoviruses, respectively) have been determined. when compared to ad5, a group c adenovirus, these sequences have been found to be 80% homologous. most changes are transitions or transversions. this high degree of nucleotide homology results in a high degree of amino acid conservation in the predicted polypeptides encoded from these genes; most nucleotide changes occu ... | 1982 | 6292051 |
| acute encephalopathy in twins due to adenovirus type 7 infection. | | 1983 | 6293428 |
| comparative sequence analysis of the inverted terminal repetition in the genomes of animal and avian adenoviruses. | the nucleotide sequences at the inverted terminal repetitions from two animal adenoviruses, infectious canine hepatitis virus and equine adenovirus, and from one avian adenovirus, celo, were analyzed. dnas from infectious canine hepatitis virus and equine adenovirus contain a homologous region which is 23 nucleotides long from the terminus. the first 17 nucleotides of this region are identical to the ones in human adenovirus type 2 dna. the striking homologous sequence of 14 nucleotides, conserv ... | 1983 | 6301151 |
| the nucleotide sequence of the genes encoded in early region 2b of human adenovirus type 7. | the nucleotide sequence of a cloned dna segment encoding the early region 2b from the group b human adenovirus ad7 has been determined. when compared to ad2, a group c adenovirus, these sequences were found to be approx. 80% homologous within the l-strand gene-coding regions. most changes are transitions or transversions, although several deletions/insertions also occur within the n-terminal domain of one of the coding regions. the substantial nucleotide homology results in a high degree of amin ... | 1983 | 6301944 |
| adenovirus type 7b in a children's hospital. | between august 15 and september 15, 1980, an outbreak of infections due to adenovirus type 7b occurred at children's hospital and health center, san diego, california. during that time, four of six patients infected with adenovirus type 7b died. all patients with hospital-acquired disease had underlying respiratory compromise. cultures, adenoviral serology tests, and histories were obtained from 383 (93%) of the 410 hospital employees. all 11 people from whom adenovirus type 7 was cultured were ... | 1983 | 6302176 |
| adenovirus type 7 outbreak in a pediatric chronic-care facility--pennsylvania, 1982. | | 1983 | 6302468 |
| viral infections of the respiratory tract in hospitalized children. a study from oslo during a 90 months' period. | a diagnosis of 979 respiratory viral infections was made in hospitalized children. respiratory syncytial virus greatly out-numbered the other viruses: it caused 58% of the total virus infections and occurred in winter epidemics. influenza a and b virus occurred during late winter and spring, rhinovirus had a seasonal distribution towards spring and autumn, whereas adenovirus types 1, 2 and 5 had no distinct seasonal distribution. whereas respiratory syncytial virus were mainly associated with br ... | 1983 | 6305106 |
| extracorporeal membrane oxygenation: its role in the survival of a child with adenoviral pneumonia and myocarditis. | we report the case of a 2-year-old child with severe adenovirus type 7 pneumonia and myocarditis who survived after seven days of ecmo. our patient demonstrates the possible applications of ecmo to pediatric lung diseases and reemphasizes the importance of lung biopsy in screening possible candidates. | 1983 | 6310796 |
| prevalence of bovine herpesvirus-1, parainfluenza-3, bovine rotavirus, bovine viral diarrhea, bovine adenovirus-7, bovine leukemia virus and bluetongue virus antibodies in cattle in mexico. | | 1983 | 6316006 |
| haematemesis as a presentation of adenovirus type 7 infection. | | 1983 | 6316891 |
| variation of virus replication in primary bovine kidney cell cultures derived from 68 three-day-old calves. | primary kidney cell cultures were prepared from 68 three-day-old calves. complete monolayers of these cultures were infected separately with viral diarrhea, infectious bovine rhinotracheitis, parainfluenza, and adenovirus 7 viruses. the yield of virus from all infected cultures was calculated by plaque titer assay after 2 to 4 days' incubation. the variation of virus yield was substantial between individual cultures. | 1983 | 6318615 |
| differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large t antigen encoded by simian virus 40-adenovirus 7 hybrid viruses. | the phosphorylation patterns of cytoplasmic and nuclear forms of simian virus 40 large t antigen encoded by simian virus 40-adenovirus 7 hybrid viruses were analyzed by two-dimensional peptide mapping. the para(ct) mutant which encodes a large t antigen defective for nuclear transport was used as source for cytoplasmic large t antigen. the data suggest that the large t antigen is phosphorylated in a sequential manner at a subset of sites in the cytoplasm and at additional sites in the nucleus. | 1984 | 6323765 |
| differential extraction of tumor-specific transplantation antigen and embryonic antigen from simian virus 40- and adenovirus 7-induced sarcoma cells of hamsters with 1-butanol and 3 m potassium chloride. | simian virus 40 (sv40)-induced sarcomas and adenovirus 7-induced sarcomas (adv-7) exhibit both specific tumor-specific transplantation antigens (tsta) and cross-protective embryonic antigens at the cell surface in the lak:lvg(syr) strain of syrian golden hamsters. specific sv40 tsta could be released from the surfaces of living hamster sarcoma cells in a 2.5% crude 1-butanol extract (cbe) and served as immunogen to protect syngeneic recipients against subsequent homologous but not heterologous t ... | 1984 | 6323810 |
| structural comparisons of wild-type and nuclear transport-defective simian virus 40 large tumor antigens. | para(nt) is a defective sv40-adenovirus 7 hybrid virus which contains the entire early region of the sv40 genome and codes for the synthesis of sv40 large tumor antigen (t-ag). a transport-defective variant of this hybrid, para(ct), encodes t-ag that is not transported to the nucleus, but accumulates in the cytoplasm. the structures of t-ags extracted from wild-type (wt) sv40-, para(nt)-, and para(ct)-infected cells were compared by peptide mapping. all three types of t-ag underwent considerable ... | 1984 | 6324467 |
| sequence of the dna-binding protein gene of a human subgroup b adenovirus (type 7). comparisons with subgroup c (type 5) and subgroup a (type 12). | the adenovirus type 7 (ad7) single-stranded dna-binding protein (dbp) structural gene has been sequenced and located between 66.7 and 62.3 map units. this region codes for a protein that contains 517 amino acid residues with a calculated molecular mass of 58,240 daltons. we compared the ad7 amino acid sequence with those reported for the ad5 (kruijer, w., van schaik, f.m.a., and sussenbach, j.s. (1981) nucleic acids res. 9, 4439-4457) and ad12 (kruijer, w., van schaik, f.m.a., speijer, j.g., and ... | 1984 | 6325415 |
| the influence of iododeoxyuridine pretreatment of various cell cultures on adenovirus multiplication. | treatment of cell cultures with iododeoxyuridine (iudr) before virus inoculation may enhance the subsequent virus multiplication. this effect was studied in seven kinds of cell cultures with seven human adenoviruses from six subgenera. iudr (50 micrograms/ml) was added 24 h after the seeding of cells, left for 2 days, and removed before virus inoculation. iudr had no effect on cell proliferation. viral cytopathic effect was enhanced in many instances by iudr pretreatment. however, virus multipli ... | 1983 | 6343819 |