virus survival on inanimate surfaces. | the persistence of several types of viruses on hard, inanimate surfaces under different relative humidities, temperatures, and types of surfaces was investigated. no differences in survival on glass, vinyl asbestos tile, ceramic tile, and stainless steel were found. under conditions of low humidity and room temperature, adenovirus, poliovirus, and herpes simplex virus survived for at least 8 weeks. vaccinia and coxsackie viruses survived for at least 2 weeks but differences due to surfaces found ... | 1975 | 167927 |
epidemiology of herpesvirus and respiratory virus infections. part 1. serologic findings. | the majority of the population group studied had complement-fixation antibodies toward the following viruses: influenza type a, respiratory syncytial, cytomegalovirus, and epstein-barr. the herpesvirus infections (cytomegalovirus and epstein-barr virus) seemed to be prevalent. only low incidences of antibodies were found toward adenovirus, influenza type b, influenza type c, and parainfluenza type ii. a total of 70 aucte virus infections (increases of antibody titer) were diagnosed in 49 patient ... | 1975 | 168127 |
comparison of the sensitivity of human embryo kidney cells, hela cells, and wi38 cells for the primary isolation of viruses from the eye. | a comparison has been made of the efficiency of human embryo kidney (hek) cills, hela cells, and wi38 cells for the isolation of viruses from the eyes of patients suffering from acute conjunctivitis or keratoconjunctivitis. from a total of 99 specimens 21 adenoviruses (serotypes 3, 4, 7, 8, and 13) were isolated in hek cells, eight (serotypes 3 and 8) in hela cells, and four (serotype 3) in wi38 cells. of the ten herpes simplex viruses isolated nine were recovered in hek cells, seven in wi38 cel ... | 1975 | 168234 |
an improved quantitative micro-complement fixation test. | the technical procedures for a simple quantitative micro-complement (c) fixation test are described. major advantages of the present technique compared with the previously described method are: a) a simple measurement of the residual hemolytic activity of c by counting the radioactivity released from 51cr-labeled sensitized sheep erythrocytes (51cr-ea); b) an increased sensitivity of the test, brought about by the use of a relatively small number of 51cr-ea per reaction volume; and c) an increas ... | 1975 | 168269 |
epidemiologic investigation of reye syndrome. | | 1975 | 168340 |
the replication of adeno-associated satellite virus. the three-component system, satellite, herpes virus, and adenovirus. | | 1975 | 168396 |
murine virus susceptibility of cell cultures of mouse, rat, hamster, monkey, and human origin. | studies were initiated to determine the practicality of using various tissue cultures for the propagation of murine viruses isolated from laboratory animals. the cytopathogenic effects of 10 murine viruses known to cause disease in laboratory rodents were compared in monolayer cultures of l929, bhk-21, wi-38, bsc-1, and vero cells. the susceptibility of primary hamster embryo, hamster kidney, mouse embryo, mouse kidney, and rat embryo cell cultures was also tested. seven of the viruses produced ... | 1975 | 168428 |
viral replication in human ovarian cell culture. | a method is presented for the preparation and maintenance of human ovarian cell cultures. sections of normal ovaries removed at surgery were minced, trypsinized, and seeded as cell cultures grown in minimal essential media at 37 c. long-term, low-passage cultures were grown in quantities sufficient to permit viral studies. ovarian cells, of passage 23, were challenged with 57 known viruses. of these viruses, 52 (especially viruses of the picornavirus and adenovirus groups) produced typical cytop ... | 1975 | 168524 |
canine adenovirus type 2-induced immunity to two canine adenoviruses in pups with maternal antibody. | twenty-four beagle pups with high levels of maternal antibody to canine adenovirus type 1 (cav-1) and canine adenovirus type 2 (cav-2) were oronasally inoculated with cav-2 at 4 weeks of age. the cav-2 was isolated from pharyngeal swabs on postinoculation days 2 through 6. in spite of the infection, maternal antibody continued to decrease for 4 to 8 postinoculation weeks, and then homologous cav-2 neutralizing antibody and, to a lesser extent, cav-1 neutralizing antibody began to increase. when ... | 1975 | 168797 |
thymidine kinase isozymes of normal and virus-infected cells. | | 1975 | 169026 |
structural studies on two adenovirus 2-sv40 hybrids containing the entire sv40 genome. | | 1975 | 169085 |
physical mapping of temperature-sensitive mutations of adenoviruses. | | 1975 | 169087 |
adenovirus-infected, cell-specific, dna-binding proteins. | | 1975 | 169091 |
human adenovirus infection in monkey cells: an example of host restriction at a step late in replication. | | 1975 | 169092 |
viral dna sequences in cells transformed by simian virus 40, adenovirus type 2 and adenovirus type 5. | | 1975 | 169095 |
studies on in vitro transformation by dna and dna fragments of human adenoviruses and simian virus 40. | | 1975 | 169096 |
studies of hamster cells transformed by adenovirus 2 and the nondefective ad2-sv40 hybrids. | adenovirus 2 does not produce tumors when injected into newborn hamsters, and this failure is not corrected by the acquisition of the portion of the sv40 genome present in any of the nondefective ad2-sv40 hybrid viruses. however, nonhybrid ad2 will transform hamster cells in vitro, and these transformed cells will produce tumors when injected into newborn hamsters. this finding, taken in conjunction with other studies (graham et al., this volume; mcallister et al., 1969; mcdougall et al., this v ... | 1975 | 169097 |
adenovirus transcription. ii. rna sequences complementary to simian virus 40 and adenovirus 2dna in ad2+nd1- and ad2+nd3-infected cells. | the genomes of the two nondefective adenovirus 2/simian virus 40 (ad2/sv 40) hybrid viruses, nondefective ad2/sv 40 hybrid virus 1 (ad2+nd1) and nondefective hybrid virus 3 (ad2+nd3), were formed by a deletion of about 5% of ad2 dna and insertion of part of the sv40 genome. we have compared the cytoplasmic rna synthesized during both the early and late stages of lytic infection of human cells by these hybrid viruses to that expressed in ad2-infected and sv40-infected cells. separated strands of ... | 1975 | 169392 |
[bovine viruses and methods for their detection]. | | 1975 | 169627 |
production of species-unspecific antiviral inhibitors in cell-cultures and in chicken embryos under the influence of pyrazolon derivatives. | | 1975 | 169855 |
a new method for monitoring subclinical virus infections of the central nervous system in mice. | the course of a subclinical virus infection of the central nervous system (cns) of mice has been followed by measuring spontaneous motor activity using animex equipment. a significant drop in activity occurred on the 5th and 6th day after inoculation with the a774 (avirulent) strain of semliki forest virus (sfv) before histological changes were apparent but at the same time as maximum brain virus titre. the relationship of the fall in activity to changes in the pattern of weight gain, food and w ... | 1975 | 169870 |
viral susceptibility of a cell line derived from the pig oviduct. | seventeen of 24 rna viruses and eight of nine dna viruses replicated in a cell line derived from a pig fallopian tube. the following rna viruses grew poorly in it: the virus of transmissible gastroenteritis of pig and the swine-influenza, sendai and bovine para-influenza type 3 viruses. among other rna viruses an untyped swine para-myxovirus and some picornaviruses, rhabdoviruses and togaviruses attained high titers and produced an extensive cytopathic effect. among the dna viruses a porcine ade ... | 1975 | 169971 |
inappropriate secretion of antidiuretic hormone associated with adenovirus pneumonia. | metabolic abnormalities compatible with inappropriate secretion of adh developed during the course of severe viral pneumonia in a 17-year-old navy recruit. with a regimen of strict fluid restriction, normalization of these abnormalities occurred. marked leukopenia and hypoxia were also present, but gradually improved with resolution of the pneumonia. inappropriate adh secretion has been associated most often with bacterial pneumonia and this patient represents one of the few with viral pneumonia ... | 1975 | 170045 |
oncogenic properties of human viruses. | | 1975 | 170197 |
new human adenovirus isolated from a renal transplant recipient: description and characterization of candiate adenovirus type 34. | an antigenically distinct adenovirus is described which was isolated in march 1972 from the urine of a 17-year-old caucasian male who was experiencing fever after receiving a kidney transplant from a cadaver in february. the adenovirus could not be isolated in april from a pharyngeal swab which yielded cytomegalovirus. complement-fixation, hemagglutination-inhibition, and/or serum-neutralization tests on sequential serum specimens from the patient confirmed that the adenovirus infection occurred ... | 1975 | 170313 |
physicochemical and serological characteristics of respiratory virus fluorescein-isothiocyanate conjugates for fluorescent-antibody diagnosis. | fluorescein-isothiocyanate (fitc) conjugates were prepared by improved methods from standard reference antisera to influenza a and b, mumps, parainfluenza 1, 2, 3, and 4, herpesvirus, respiratory syncytial virus, and adenovirus hexon. the antisera, prepared in a variety of animals, were fractionated three times with selected optimal concentrations of ammonium sulfate and yielded gamma globulins of adequate purity for conjugation with fitc. conjugates containing optimal fluorescein-to-protein rat ... | 1975 | 170315 |
inhibition of melanoma growth in hamsters by type-2 adenovirus. | type-2 adenovirus was shown to inhibit the growth of transplantable hamster melanoma in 70% of syrian hamsters without any injurious effect to the host. greatest inhibition of tumor formation was seen when animals were injected with 10(6) tcd50 of adenovirus and 2.5 x 10(5) tumor cells, or 10(6) tcd50 of virus and 5.0 x 10(5) tumor cells followed either 1 or 7 days later by a second injection of a similar dose of virus. significant inhibition in tumor growth was also noted when 2 injections of v ... | 1975 | 170480 |
transplatation resistance to adenovirus-induced hepatocellular carcinomas. | two transplantable hepatic carcinomas of the hamster contained celo virus-induced tsta, confirming the etiological role of this avian adenovirus in the induction of hepatic tumors. transplantation resistnace could not be induced with oncogenic adenoviruses of human, simian, or canine origin. | 1975 | 170623 |
a review of routine tests for respiratory viruses in hospital inpatients. | during the period june 1967 to may 1972, viral tests were performed upon 1195 inpatients aged 12 and over in the brompton hospital. the overall diagnostic rate was 21-5%, comparing 9-3% by isolation and 14-9% by complement fixation (6-5% by four-fold rises in titre in paired sera, 8-4% by titres larger than or equal to 160 in single sera). only 42% of all patients had an acute respiratory illness within one week prior to admission, which seriously curtailed the chances of isolating viruses and o ... | 1975 | 170701 |
molecular biology of adenoviruses. | | 1975 | 170728 |
the alteration of ribosomes for mrna selection concerned with adenovirus growth in sv40-infected simian cells. | | 1975 | 170741 |
virological studies on gynaecological patients. | endometrial epithelial cells and blood samples taken simultaneously with the curettage (first serum) of 138 patients suffering from menstrual bleeding disorders as well as materials obtained from 16 induced abortions, were studied for the presence of virus. fourteen adenovirus 2 strains were isolated from samples of the patients. endometrial epithelial cells of 35 patients were examined with immunofluorescence method and 23 of them displayed specific fluorescence referring to the presence of vir ... | 1975 | 170759 |
fatal disseminated adenovirus infection in a renal transplant recipient. | a 61 year old woman died of diffuse interstitial adenovirus pneumonia 55 days after receiving a cadaveric renal allograft. the adenovirus was serologically distinct from the 33 known human adenovirus serotypes and appears to represent a new human adenovirus. pathologic and virological findings indicate that the pneumonia was only one manifestation of a disseminated infection, the source of which may have been a latent adenovirus infection preexisting in the donor kidney. the establishment of the ... | 1975 | 170822 |
[ultrastructure of experimental virus-induced hemangiopericytomas]. | electron-microscopy studies of malignant low-differentiated hemangiopericytomas, induced by adenovirus of monkeys sa7(c8) and bovine adenovirus type 3 were, carried out. at earlier stages of the development of these tumours in tumourous cells located around capillaries there were observed the ultrastructural characteristics typical of pericytes and cells of human hemangiopericytis: the presence of the basal layer and fibrills as thick as 40 a. as differentiation proceeded, tumorous cells acquire ... | 1975 | 170893 |
nonbacterial respiratory infections. | | 1975 | 171127 |
a second specific endonuclease from haemophilus aegyptius. | | 1975 | 171410 |
physical mapping of temperature-sensitive mutations of adenoviruses. | | 1975 | 171416 |
differential response to cytochalasin b among cells transformed by dna and rna tumor viruses. | mouse, hamster, rat, human, and chick cells were transformed by rna and dna tumor viruses: simian virus 40, adenovirus type 7, kirsten mouse sarcoma virus (ki-musv), moloney mouse sarcoma virus, and rous sarcoma virus. all cultures of transformed cells grew to high concentration densities. normal and transformed cells were treated with cytochalasin b (cb) at concentrations preventing cytoplasmic cleavage. cells altered by dna tumor viruses responded to cb with numerous nuclear divisions resultin ... | 1975 | 171432 |
effect of adeno-associated virus on cancer expression by herpesvirus-transformed hamster cells. | infection of herpes simplex virus type-2-transformed hamster tumor cells with adeno-associated virus type 1 before inoculation into hamsters specifically delayed the appearance of palpable tumors and increased the survival time of the animals. the data indicated that a defective virus of humans can influence cancer expression by a virus-transformed cell. | 1975 | 171433 |
simian virus 40-specific proteins in hela cells infected with nondefective adenovirus 2-simian virus 40 hybrid viruses. | the synthesis of simian virus 40 (sv40)-specific proteins in hela cells infected with the nondefective adenovirus 2 (ad2)-sv40 hybrid viruses, ad2+nd2, ad2+nd3, ad2+nd4, and ad2+nd5, was investigated. infected-cell proteins were labeled with radioactive amino acids late after infection, when host protein synthesis was shut off, and analyzed by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. all polypeptides normally seen in ad2-infected cells were found in cells inf ... | 1975 | 171451 |
[mitosis and virus infection in cell cultures. ii. reaction of the nuclear apparatus of the cell to virus infection]. | | 1975 | 171878 |
neurologic complications with elevated antibody titer after acute hemorrhagic conjunctivitis. | nine patients with polyradiculomyeloneuropathy after acute hemorrhagic conjunctivitis (ahc) infection were studied serologically. all except one patient had neutralization titers larger than or equal to 1:16 against the prototype j670/71 strain of ahc virus in at least one of their serum samples. the development of a significant fourfold rise in antibody titer against ahc virus occurred in one of the patients who developed neurologic complications five days after the onset of ahc infection. | 1975 | 171960 |
cell-to-cell attachments and associations in tumors induced by celo virus or virus-transformed cells in hamsters. | cell-to-cell attachments or associations in expermentally induced sarcoma of chicken embryo lethal orphan virus (avian adenovirus) origin were studied in hamsters by electron microscopic examination. in many instances, the neoplastic cells seemed to be held together either by desmosome-like structures or an "interlocking" of their apposing plasma membranes. less frequently, the cells were attached by button-like projections between the cell surfaces. only rarely, interdigitation occurred between ... | 1975 | 171984 |
studies on the biochemical basis for the antiviral activities of some nucleoside analogs. | | 1975 | 171994 |
the immunological response of calves after submucosal application of a live vaccine against parainfluenza-3- and adenovirus. (brief report). | using submucosal application of live attenuated vaccine against parainfluenza-3-virus and cattle adenovirus within the nasal opening, calves reacted with the formation of secretory (local) and serum antibodies of significantly higher titers than are received using subcutaneous application. the same vaccine induces interferon activity in the serum and nasal secretion after submucosal vaccination. adenovirus antigen is a stronger interferon inducer than para-influenza-3-virus. | 1975 | 172040 |
rna type c virus antigens in hamster cells transformed by carcinogenic dna viruses and chemicals. | the passive hemagglutination inhibition technique was used to test serologically for the presence of syrian hamster type c virus antigen(s) (shcva) in a wide variety of normal and transformed hamster cells and tissues. shcva could not be detected in normal tissues or nonneoplastic tissues of tumor-bearing syrian hamsters. normal hamster embryo cells or cells transformed in vitro by simian adenovirus, by chemical alone, or doubly transformed by simian adenovirus and chemical did not contain shcva ... | 1975 | 172234 |
integration of viral dna into the host genome. | | 1975 | 172288 |
regional localization of human genes in virus-induced uncoiler regions. | | 1975 | 172292 |
detection of virus-specific dna and rna base-sequences in individual cells transformed or infected by adenovirus type 2. | by means of 3h thymidine-labelled adenovirus 2 dna, adenovirus-specific dna sequences have been localized in individual nuclei of adenovirus 2- or 12-infected cells, and adenovirus-specific rna sequences have been detected in the permissive cells as well as in cells transformed by adenovirus type 2. the ability to detect such specific virus rna base-sequences in particular, by in situ hybridization, should be useful in studying the transcriptional specificities of tumours and neoplasms. | 1975 | 172461 |
synthesis of herpes simplex virus, vaccinia virus, and adenovirus dna in isolated hela cell nuclei. i. effect of viral-specific antisera and phosphonoacetic acid. | purified nuclei, isolated from appropriately infected hela cells, are shown to synthesize large amounts of either herpes simplex virus (hsv) or vaccinia virus dna in vitro. the rate of synthesis of dna by nuclei from infected cells is up to 30 times higher than the synthesis of host dna in vitro by nuclei isolated from uninfected hela cells. thus hsv nuclei obtained from hsv-infected cells make dna in vitro at a rate comparable to that seen in the intact, infected cell. molecular hybridization s ... | 1975 | 172658 |
block to multiplication of adenovirus serotype 2 in monkey cells. | the block to adenovirus 2 (ad2) multiplication in monkey cells can be overcome by coinfection with simian virus 40 (sv40). to identify this block we have compared the synthesis of ad2 proteins in monkey cells infected with ad2 alone (unenhanced) or with ad2 plus sv40 (enhanced). synthesis of viral proteins in enhanced cells was virtually identical to that found for permissive infection of human cells by ad2 alone. in contrast, the unenhanced cells were strikingly deficient in the production of t ... | 1975 | 172661 |
[respiratory tract infections of viral origin in infants. examination of 103 serum pairs in autumn and following spring]. | in autumn 1973 und about four months later in spring 1974 blood samples were taken from the same 103 children aged from a few months to five years and coming from different parts of bavaria. we examined the samples for complement-fixing antibodies against the influenza virus types a, b and c, the parainfluenza virus types 1, 2 and 3, the adenoviruses and the respiratory-syncytial virus, and for neutralising antibodies against the echo virus type 25. at the commencement of the investigation the m ... | 1975 | 172769 |
cytopathology in viral diseases. | | 1975 | 172783 |
[viruses and brain tumors (author's transl)]. | this brief review paper deals mainly with oncogenic dna viruses originally isolated from human patients, i.e., human adenoviruses and human papova jc viruses. human adenovirus type 12 was first isolated in 1953 in cell cultures derived from the adenoids of infected children. since then, 32 antigenic types of human adenovirus have been identified. at least eight serotypes (12, 18, 31, 3, 7, 14, 16, and 21) are now known to be capable of producing tumors in newborn rodents. a direct causal relatio ... | 1975 | 172819 |
[letter: epidemic conjunctivitis due to b type adenovirus]. | | 1975 | 172869 |
[complement fixation reaction (cfr) in adenovirus infections of calves]. | studied was the complement-fixation reaction in the diagnosis of the adenovirus infections in calves. it was found that the test is specific and sensitive. a virus suspension of tissue cultures was used as an antigen, its titer varying from 1:8 up to 1:16. specific complement-fixing antibodies were detected mainly in survivals at serum dilution of up to 1:64. specific antibodies were established in undiluted sera too taken from animals of infected herds. in some of the tested sera there were bot ... | 1975 | 173074 |
a study of the sequences of chicken embryo lethal orphan (celo) virus dna present in a transformed hamster cell line with use of specific fragments of the virus genome. | | 1975 | 173080 |
acute posterior multifocal placoid pigment epitheliopathy associated with an adenovirus type 5 infection. | a 19-year-old black man with acute posterior multifocal placoid pigment epitheliopathy had concurrent positive viral cultures and rising antibodies to adenovirus type 5. this finding, considered together with earlier reports of viral-like syndromes accompanying the disease, supports the implication of a respiratory virus as a possible etiologic factor. | 1975 | 173190 |
adenovirus respiratory infection in turkey poults. | a virus from turkey poults with respiratory signs was isolated in specific-pathogen-free embryonated chicken eggs and subsequently adapted to chicken embryo fibroblast and turkey kidney cell cultures, where round cell formation was observed. the cloned virus was ether-resistant and incorporated tridiated thymidine. intra-nuclear icosahedral virus particles of 80 nm were detected. these physicochemical characteristics place this isolant into the adenovirus group of viruses. the disease was experi ... | 1975 | 173277 |
the roles of the infectious bursal agent and several avian adenoviruses in the hemorrhagic-aplastic-anemia syndrome and gangrenous dermatitis. | the effect that breeder-flock immune status regarding the infectious bursal agent (iba) and two avian adenoviruses (dpi-1 and dpi-2) has on the susceptibility of their commercially reared delmarva broiler progeny to the hemorrhagic-aplastic-anemia syndrome and concurrent gangrenous dermatitis was determined. lack of immunity to the iba in breeder flocks was related to an increased susceptibility of progeny to anemia and dermatitis. breeder-flock immunity to the two adenoviruses tested could not ... | 1975 | 173278 |
hemagglutinating properties of celo, an oncogenic avian adenovirus. | chicken-embryo-lethal-orphan (celo) virus, phelps strain, agglutinated erythrocytes at 37 c. the hemagglutinating activity, which is a function of complete and incomplete virus particles, was sensitive to heat but not to ph. the soluble components of the virus were similar in sedimentation characteristics to those obtained from human adenovirus type 1. the effects of chemical and physical agents on celo hemagglutinin, celo infectivity, and red-cell receptors suggested that the last were protein ... | 1975 | 173279 |
an epidemic of picornavirus and adenovirus conjunctivitis. | a pandemic of acute haemorrhagic conjunctivitis occurred in south-east asia during 1970 and 1971, and became epidemic in lucknow in may 1971. from the conjunctival swabs adenovirus-like agents were isolated in monkey kidney tissue culture; one was typed as adenovirus 2. in paired sera rising antibody titres were found against an adeno-like agent isolated and the picornavirus (ec2/71) isolated in singapore. the epidemics in south-east asia were caused by a picornavirus while in lucknow both adeno ... | 1975 | 173388 |
regional localization of human genes in virus-induced uncoiler regions. | | 1975 | 173436 |
[etiology and prevention of recurring aphthous stomatitis]. | new results concerning the etiology of recurrent aphthae are reported. according to own experiments of the authors, adenoviruses persisting in the epithelial cells of the oral mucosa may sensitize the aphthous patient. adenovirus antigen was demonstrable in the oral mucosa cells in more than 50% of the patients and in the lymphocytes in approx. 1% of the patients. lymphoblast transformation in the circulating lymphocytes could be demonstrated in vitro with heat-inactivated type 1 adenovirus, in ... | 1975 | 173517 |
viral-induced thymidine kinase isozymes. | | 1975 | 174152 |
[study of the organotropic and oncotropic properties of human type 16 adenovirus in the body of syrian hamsters and mice (author's transl)]. | human adenovirus type 16 was studied in syrian hamsters bearing sv40 virus induced transplantable tumour and in mice of black line with lewis cancer. despite its tropism to the tumour tissue, the virus injected into the blood stream was first accumulated in the lung tissue and in organs of the reticuloendothelial system (the spleen and liver). when the tumour was in the lung tissue of mice, the virus content in it was much higher than in a similar tumour of subcutaneous localization. | 1975 | 174323 |
survey of adenovirus and respiratory syncytial virus antibodies in pondicherry area--south india. | | 1975 | 175011 |
a review of adenoviruses in the etiology of acute hemorrhagic cystitis. | in a comparison of children with acute hemorrhagic cystitis it was noted that 51 per cent of those in sendai, japan and 23 per cent of those in chicago, illinois had adenoviruria during their illness. these 2 populations are the only ones in which the disease has been studied and reported. in both populations male outnumbered female patients, with a ratio of 3.4 to 1 in japanese children and 2.3 to 1 in american children. adenovirus type 11 was isolated exclusively in both studies, with the exce ... | 1976 | 175174 |
virus infections and acute renal transplant rejection. | the date of onset of 360 acute renal transplant rejection episodes from 1969 to 1973 have been compared with the prevalence of various common viral infections and infections due to mycoplasma pnuemoniae. a positive correlation was found for influenza b infections (r=0.43, p less than 0.01) up to 5 months before transplantation and for adenovirus infections (r=0.32, p less than 0.05) at 1 month before kidney grafting. | 1976 | 175308 |
occurrence of reo-like calf viruses in young children with acute gastroenteritis. diagnoses established by electron microscopy and complement fixation, using the reo-like virus as antigen. | in the course of a six-month-study of acute gastroenteritis in children of ages up to six years, a reo-like virus was found in 54 per cent of the faecal specimens obtained at an early stage of the disease, using electron microscopy as screening test. by means of a concentrated complement fixation antigen, composed of a related calf diarrhoea virus cultivated in tissue culture, the rise in titre was found to be significant in 96 per cent of the patients whose faeces contained the reo-like virus. ... | 1976 | 175639 |
[different ultrastructural models of adenovirus aggregation: their value in virological diagnosis]. | | 1975 | 175809 |
immunofluorescent detection of adenovirus antigen in epidemic keratoconjunctivitis. | an immunofluorescent technique was used to demonstrate soluble adenoviral antigens in epithelial cells on conjunctival scrapings of patients with epidemic keratoconjunctivitis (ekc). conjunctival scrapings for immunofluorescence and viral isolation studies were performed on 79 patients suspected of having ekc or other acute follicular or papillary conjunctivitides. of 41 patients with clinical findings consistent with a diagnosis of ekc and three patients with pharyngoconjunctional fever, 43 wer ... | 1976 | 176130 |
[obtaining the beta-globulin fractions from swine and cattle sera and a study of their immunological activity]. | the rivanol precipitation was used to obtain beta-globulin fractions from specific swine sera against edema disease, paratyph and aujeszky's disease as well as from normal ovine and swine sera. agar electrophoresis revealed that the preparations produced contained beta-globulin (86 per cent), gamma-globulin (5 per cent), and alpha2-globulin (9 per cent). the beta-globulin preparations were studied for the presence of antibodies against e. coli, salmonellae, staphylococci, myxovirus parainfluenza ... | 1976 | 176771 |
suppression of the temperature-sensitive character of adenovirus 12 early mutants in monkey cells transformed by an adenovirus 7-simian virus 40 hybrid. | | 1976 | 176780 |
the spectrum of virus resistance of a kb cell strain resistant to diphtheria toxin. | | 1976 | 176795 |
[recognition of influenza and other acute respiratory virus infections and their combinations by means of immunofluorescence]. | the results of postmortem examinations performed in 237 fatal cases of influenza and other acute respiratory diseases are presented. in smears of organs and tissue culture cells infected with these materials and heart blood the immunofluorescent procedure detected influenza virus antigens in 67% of the cases, antigens of other respiratory viruses in 53% including 18-19% of mixed infections. parallel immunofluorescent studies in living patients and isolation of influenza virus and adenoviruses in ... | 1975 | 176823 |
[lipid composition of cellular systems following viral infection of the upper respiratory tract. ii. determination of the content of total lipids, phospholipids and neutral lipids in cells infected with respiratory viruses]. | | 1975 | 176826 |
[lipid composition of cellular systems following respiratory virus infection. iii. determination of fatty acid composition by gas chromatography]. | | 1975 | 176827 |
[application of a demographic method for the study of adenoviruses and herpesviruses in a closed infantile community (author's transl)]. | rate of seroconversions to adenoviruses, cytomegaloviruses (cmv) and epstein-barr virus (ebv) was studied from 1965-1973 in 200 infants living in a closed infantile community. the transversal demographic table method was used to evaluate the results of sera examined. seroconversion occurs earlier in the case of adenoviruses with also possess in higher intensity of infection. the intensity of seroconversions to ebv capsid antigen is a little lower, but of all three viruses examined, the spreading ... | 1975 | 176843 |
[virucidal activity of the disinfectant "gigasept" against different enveloped and non-enveloped rna-and dna-viruses, pathogenic for men. i. investigation in the suspension test (author's transl)]. | "gigasept" is a highly efficient chemical disinfectant on the basis of succine dialdehyde and form aldehyde. the virucidal capacity was assayed in the suspension test procedure with different representative rna and dna viruses with and without an envelope, such as polio wild virus type i, coxsackie virus type b 3, adeno virus type 3, herpes virus type ) and vaccinia virus. parameter for disinfectant activity was the virus inactivation kinetic, i. e. interdependence of titer reduction vs. disinfe ... | 1975 | 176845 |
[the condition of mitochondria in experimental viral carcinogenesis]. | a parallel histoenzymatic and electron-microscopy study of the state of mitochondria in experimental viral cancerogenesis induced by adenovirus of monkeys sa7(c8) and virus of rous sarcoma in soft tissues of hamster was carried out. it was shown that the earliest changes in the cell in the process of its tumorous transformation were those in mitochondria. the character of deposits of diformazin at an early stage of viral cancerogenesis corresponded to the trend to the linear arrangement of mitoc ... | 1975 | 176979 |
the oncogenic potential of some avian adenoviruses causing diseases in chickens. | the oncogenic potentials of three different strains of avian adenoviruses (the tipton strain of the inclusion body hepatitis virus, the dpi-2, and the indiana c viruses) were investigated in newborn hamsters. animal inoculations were via two routes, subcutaneous and intracerebral. all three viruses proved nononcogenic for the hamsters observed over a period of 225 days. however, lesions of hepatitis similar to those of inclusion body hepatitis of chickens were seen in three hamsters inoculated w ... | 1976 | 176986 |
isolation and identification of a turkey respiratory adenovirus. | a virus with physical and biological characteristics of an adenovirus was isolated from turkey poults with respiratory disease. the virus was ether-resistant and incorporated [3h] thymidine. electron microscopy revealed virions of icosahedral configuration, approximately 78 nm in diameter, within the nuclei of infected cells. the virus produced cytopathology in turkey kidney cells, but did not produce observable disease when inoculated into commercial turkey poults or specific-pathogen-free embr ... | 1976 | 176992 |
antigenic characterization of intermediate adenovirus 14-11 strains associated with upper respiratory illness in a military camp. | an unusual variant of adenovirus (av) 11 was isolated from throat and rectal swabs from six persons with upper respiratory illness in a spanish military camp in march 1969. the same strain was serologically related to the upper respiratory illness of seven other men among 25 sample cases studied in detail. after strain purification, the virus was grouped as an av by standard biological tests; it possessed the usual titers of group-specific hexon antigen but only low hemagglutinin titers (1:4 to ... | 1976 | 177365 |
electron microscope study of experimental enteric adenovirus infection in mice. | using fluorescent antibody techniques (fa) and light microscopy (lm) and electron microscopy (em), this paper describes the morphological features of the ileum in the dk1 mouse orally challenged with adenovirus k87. at the peak of infection, virus is easily identified by fa in the epithelium of the villi and crypts of the ileum. lm shows that fluorescent cells have large, bizarre, uniformly basophilic nuclei containing deoxyribonucleic acid, as indicated by histochemical tests. em further identi ... | 1976 | 177370 |
coxsackievirus and adenovirus infection. association with acute febrile and juvenile rheumatoid arthritis. | the prearthritic manifestations of juvenile rheumatoid arthritis in a 16-year-old boy were associated with a rise in coxsackievirus b3 and a9 neutralizing antibody titers from 1:16 to larger than or equal to 1:512, and 1:64 to 1:512, respectively. recurrent polyarthritis followed and has persisted for three years. adenovirus 7 was isolated from the pericardial fluid of a 9-year-old girl in whom juvenile rheumatoid arthritis then developed. of 11 patients with acute, nonspecific, febrile arthriti ... | 1976 | 177792 |
viral respiratory infections. | | 1976 | 177853 |
studies on the presence of viral antibodies in patients with various forms of malignant neoplasia. | the study of viral antibodies in 6714 sera demonstrated that the level of antibodies to infectious viruses was the same in cancer patients as in controls. however, the patients with various forms of neoplasia showed a considerable percentage and high antibody levels to viruses with oncogenic potential for animals (adenovirus, sv40, rous virus) or involved in human carcinogenesis (herpes virus). | 1975 | 178091 |
isolation of viruses and mycoplasmas from middle ear effusions: a review. | reports of studies of middle ear effusions (mee) obtained by needle aspiration are reviewed in this paper; viruses were isolated from 29 of 663 patients (4.4%) and respiratory syncytial virus was isolated most frequently (22 patients); only one mycoplasma, m. pneumoniae, was recovered from the mee of 771 patients. viruses were also sought from the throat or nasopharynx of 249 patients with mee; 59 patients (23.7%) had a respiratory virus present. m. pneumoniae was isolated from the throat or nas ... | 1976 | 178266 |
integration of dna tumor virus genomes. | | 1976 | 178480 |
the replication of papovavirus and adenovirus dna. | | 1976 | 178481 |
adenoviral keratoconjunctivitis. | | 1975 | 178620 |
presumptive viral keratoconjunctivitis, mononucleosis, and the oncogenic viruses. | | 1975 | 178621 |
simian virus 40-specific polypeptides in ad2+ nd1- and ad2+ nd4-infected cells. | a comparison of the proteins synthesized in human cells at late times after infection with adenovirus (ad2) and with the adeno-simian virus 40 (sv40) hybrid viruses revealed polypeptides of 30,000 and 92,000 molecular weight specific for the hybrid viruses ad2+nd1 and ad2+nd4, respectively. cell-free translation of sv40-specific mrna, prepared from these cells by hybridization of total cytoplasmic rna to sv40 dna, showed that the mrna's specifying these two polypeptides were at least partially e ... | 1976 | 178903 |
characterization of simian cells tranformed by temperature-sensitive mutants of simian virus 40. | seven lines derived from primary african green monkey kidney cells, which had survived lytic infection by wild-type simian virus 40 (sv40) or temperature-sensitive mutants belonging to the a and b complementation groups, were established. these cultures synthesize sv40 tumor (t) antigen constitutively and have been passaged more than 60 times in vitro. the cells released small amounts of virus even at high passage levels but eventually became negative for the spontaneous release of virus. virus ... | 1976 | 178917 |
[the etiology of epidemic keratoconjunctivities (author's transl)]. | in 93 patients (mostly sporadic cases) with suspected ekc an infection with adenoviruses was proved by virological and serological methods in 54 cases. types 8, 3, 7, 19, 4, and 14 were found in 38, 6, 5, 3, 1, and 1 cases respectively. 33 out of 48 patients with clinically typical ekc had an infection with type 8. from the patients without adenoviral infection, the absence of which having been proved by extensive serological tests, 7 showed a typical ekc. the symptoms considered as relatively t ... | 1975 | 178946 |
[poliovirus and simian adenovirus replication in mixed infections of primary monkey kidney cell cultures]. | | 1976 | 178967 |
characterization of an adenovirus early protein required for viral dna replication: a single strand specific dna binding proteins. | 1. the human adenoviruses types 2, 5 and 12 code for the production of a single strand specific dna binding protein. the molecular weights of these proteins were 72,000 for types 2 and 5 and 60,000 for type 12. in all three cases proteolytic breakdown fragments of these binding proteins (48,000 mw) were also observed. 2. analysis of the methionine containing tryptic peptides of these proteins indicate that the types 2 and 5 proteins are similar and clearly distinguishable from the type 12 protei ... | 1976 | 178993 |
[study of the pathogenic qualities of 4 celo-virus strains isolated in bulgaria]. | four celo virus strains, isolated in this country, were used to infect 3-day-old chicks via the trachea, muscularly, orally, subcutaneously, and cerebrally. the chicks were killed on the 2nd, 4th, 6th, 9th and 16th day following inoculation. material was taken from each chick for morphologic, virologic, and serologic examination. the clinical course of the disease was also followed up. prior to killing some birds showed infirmity, difficult breathing, slightly expressed diarrhia, going off food, ... | 1975 | 179190 |
[clinical aspects of nervous system disorders in association with viral antigens and meningococcus in the cerebrospinal fluid]. | | 1976 | 179215 |