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[corticoid activation of infectious bovine rhinotracheitis virus--infectious pustular vulvovaginitis virus (ibr-ipv)].the course of infection and ibr virus reactivation was studied in three experimentally infected weaned calves and three cows from naturally invaded herds. the animals were infected intranasally, intratracheally, and by contact. after 20, 41, and 105 days from primary infection, both in calves and in cows, dexametazon was applied in a series of six to seven intramuscular injections. the presence of the virus was examined in the nasal, conjunctival, vaginal and/or preputial secretions and in blood ...1976190757
mitogen- and antigen-responsive milk lymphocytes. 1977191200
demonstration and quantitation of immunoglobulins in bovine serum, follicular fluid, and uterine and vaginal secretions with reference to bovine viral diarrhea and infectious bovine rhinotracheitis.immunoglobulin concentrations (igg, igm, and iga) in bovine serum, follicular fluid, and uterine and vaginal secretions were determined. the specificities of igg, igm, and iga for virus-neutralizing antibody against bovine viral diarrhea (bvd) and infectious bovine rhinotracheitis (ibr) viruses were also examined. high concentrations of igg were present in both serum and follicular fluid. the igg, igm, and iga concentrations were low in uterine and vaginal secretions. there was more igg in the u ...1977192113
freeze-etching observations on infectious bovine rhinotracheitis virus in the nucleus of bovine kidney cells. 1977192181
mechanisms of resistant of herpesviruses: comparison of the effectiveness of different cell types in mediating antibody-dependent cell-mediated cytotoxicity.enriched populations of polymorphonuclear leukocytes (pmn) and macrophages obtained from the mammary gland and of granulocytes (pbg) and lymphocytes (pbl) prepared from peripheral blood of the same animal were compared for their ability to mediate antibody-dependent cell cytotoxocity against antibody-sensitized infectious bovine rhinotracheitis virus-infected target cells (ibr-gbk) and antibody-sensitized chicken erythrocyte targest (crbc). the order of effectiveness was pmn leads to macrophages ...1977192672
experimental infection of rabbits with the virus of infectious bovine rhinotracheitis.adult and newborn rabbits were infected with the la strain of infectious bovine rhinotracheitis virus. adult rabbits developed only mild, self-limiting conjunctivitis, but had microscopic inflammatory foci in the liver and adrenal glands. newborn rabbits developed a severe, sometimes fatal, generalized infection with focal and diffuse necrosis of the liver and adrenal glands.1977193550
[use of inactivated vaccine against infectious rhinotracheitis--pustular vulvovaginitis (ibr-ipv) in calves and pregnant cows].a total of twelve batches of an inactivated vaccine against ibr--ipv, obtained by the authors, were tested in the practice. vaccinated were 212 calves and 1172 cows and heifers on five dairy farms in different communities. on the basis of virologic, serologic, clinical and epizootiologic investigations the conclusions were drawn that the vaccine is harmless and highly immunogenic. in subcutaneous application at the rate of 3 cm3, twice, it renders protection against ibr--ipv infection (respirato ...1977197686
[isolation of the virus and the clinico-morphological characteristics of infectious bovine rhinotracheitis in young calves]. 1977198943
effect of hydrocortisone on the interferon response of calves infected with infectious bovine rhinotracheitis virus. 1977199091
an outbreak of infectious pustular vulvovaginitis in beef heifers vaccinated against infectious bovine rhinotracheitis. 1977199977
immunogenicity studies on an inactivated ibr vaccine administered into the nasal mucosa. 1976200131
clinical and immunologic responses of cattle to infectious bovine rhinotracheitis virus after infection by viral aerosol or intramuscular inoculation.aerosol or intramuscular exposure to infectious bovine rhinotracheitis virus elicited generally comparable levels of serum antibody in cattle, but not measurable nasal secretion antibody. aerosol-exposed cattle developed signs of mild clinical disease, fever, and leukopenia and shed virus from their nasal passages. cattle exposed by intra-muscular inoculation developed a brief febrile response and leukopenia but did not shed virus. after an aerosol challenge exposure, cattle in each group develo ...1977201185
susceptibility of bovine macrophage and tracheal-ring cultures to bovine viruses.cultures of macrophages initiated from peripheral blood monocytes and organ cultures of tracheal rings were tested for their susceptibility to bovine viruses. with several notable exceptions, viruses cytopathogenic for bovine embryonic lung cultures were cytopathogenic for macrophages. although cowpox virus replicated in macrophages, pseudocowpox did not, and although pseudorabies virus replicated within macrophages, infectious bovine rhinotracheitis and dn-599 herpesviruses did not. bluetongue ...1977201195
investigation of causative agents of bovine respiratory tract disease in a beef cow-calf herd with an early weaning program.serum samples were collected from early weaned fall calves shortly after the onset of respiratory tract disease. antibody titers to infectious bovine rhinotracheitis (ibr) virus, parainfluenza type 3 (pi-3) virus, bovine viral diarrhea (bvd) virus, bovine adenovirus type 3 (bav-3), and bovine respiratory syncytial virus (brsv) were determined on paired (acute and convalescent) serums. seroconversion rate (a fourfold or greater rise in antibody titer) for ibr virus was 4.3%, pi-3 virus--16.3%, bv ...1977201196
use of polyethyleneglycol-treated serum for animal cell cultures.although many proteins will be removed from sera by precipitation with 10% polyethyleneglycol (peg) the growth-promoting properties of such peg-treated sera for many cell lines and cell strains are hardly reduced. among the precipitated proteins are the macroglobulins which are difficult to remove from cell cultures and which may cause allergic reactions if incorporated into vaccines. the gammaglobulins are removed in this way as well. if the sera are contaminated with viruses or phages the titr ...1976201528
enhancement of antibody-dependent cell-mediated cytotoxicity of herpesvirus-infected cells by complement.an investigation was made of the effects of complement on the levels of antibody-dependence cytotoxicity (adcc) mediated by bovine leukocytes against herpesvirus-infected target cells. neutrophil-mediated adcc was considerably enhanced upon the addition of low levels of complement that alone failed to induce lysis of antibody-sensitized target cells. this enhancement was most apparent under suboptimum conditions such as at low effector-to-target cell ratios, low levels of sensitizing antiserum, ...1977201564
infectious bovine rhinotracheitis: a review and update.infectious bovine rhinotracheitis (ibr), a herpesvirus infection of cattle, has diverse clinical manifestations. known mainly as a respiratory tract disease characterized by tracheitis, rhinitis, and fever, ibr plays a prominent role among causes of undifferentiated bovine respiratory disease and abortion. it also causes conjunctivitis, infectious pustular vulvovaginitis, balanoposthitis, and rarely, encephalitis. the virus is readily transmitted and has worldwide distribution. some cattle devel ...1977201597
[isolation of the infectious bovine rhinotracheitis virus on the cultures of transplanted cells]. 1977202061
[herpetic infection of the propagator bulls]. 1977202063
[serological response of rabbits following immunization with m. parainfluenzae-3, adenovirus i and infectious bovine rhinotracheitis virus associated antigens].the immunization of rabbits separately with virus suspensions of myxovirus parainfluenzae-3, adenovirus serotype i, and bovine rhinotracheitis virus or with combinations of each two of them and with a combination of all three viruses led to the production of sera having titers of virus-neutralizing antibodies acting against each of the antigens that participated in the combination. results showed that no inhibition existed of the antigens during immunization as established by the serologic respo ...1977202065
time required to stimulate protection with intranasal administration of a temperature-sensitive, infectious bovine rhinotracheitis virus vaccine. 1978204095
[immunoprophylaxis of infectious bovine rhinotracheitis].the live attenuated vaccine against infectious rhinotracheitis (lav), the live trivaccine against infectious rhinotracheitis (lt), the concentrated etanolsaponin vaccine against infectious rhinotracheitis (cesv) and the ethanol-saponin vaccine against infectious rhinotracheitis (esv) can all be used as immunoprophylactic means in the control of infectious rhinotracheitis in cattle. the first two live vaccines are applied to calves in infection foci, and the two inactivated vaccines are used with ...1977204103
maternal immunity to infectious bovine rhinotracheitis and bovine viral diarrhea viruses: duration and effect on vaccination in young calves.the immune response to modified live-virus bovine viral diarrhea (bvd) vaccine and infectious bovine rhinotracheitis (ibr) vaccine was examined in calves that had received passive maternal antibodies to these viruses. blood serum samples from vaccinated and control (nonvaccinated) calves were examined for more than 1 year to determine the rate of decline of passive anti-bvd and anti-ibr antibodies and the effect that vaccination had on these antibody titers. the control calves lost their antibod ...1978204233
evaluation of the safety and efficacy of an intranasal vaccine containing a temperature-sensitive strain of infectious bovine rhinotracheitis virus. 1978206171
efficacy of an intranasal infectious bovine rhinotracheitis vaccine for the prevention of abortion in cattle. 1978206336
chromic-acid formaldehyde fixation of nucleic acids of bacteriophage phi6 and infectious bovine rhinotracheitis virus.bacteriophage phi6 nucleic acid was present as a torus after chromic acid-formaldehyde-oso4 fixation and acetone and propylene oxide dehydration. a herpes virus, infectious bovine rhinotracheitis virus, had its dna mostly as a torus, collapsed in the centre, or as a network, after glutaraldehyde-oso4 fixation, but in an uncollapsed torus or network formation after chromic acid-formaldehyde-oso4. this fixative stabilized nucleic acids, allowing acetone dehydration and plastic embedding without co ...1978206662
[the immune response of normal and leukotic cattle to ibr-ipv-virus (author's transl)]. 1978207049
an investigation into the basic virus-antibody neutralization reaction, with special regard to the reaction in the constant-virus/varying-serum neutralization test. 1978207177
neutralizing antibodies to bovid herpes virus 1 (infectious bovine rhinotracheitis/infectious pustular vulvo-vaginitis) in african wildlife with special reference to the cape buffalo (syncerus caffer). 1978207748
the occurrence, control, and eradication of infectious bovine rhinotracheitis virus infection at artificial insemination centres in denmark. 1978208052
persistence of infection with infectious bovine rhinotracheitis virus in danish cattle herds.the later course of ibr virus infections in 11 dairy herds in endemic areas and in an imported beef herd is described. in 2 herds the infection was limited to those animals which developed a genital infection after insemination with semen from an infected ai centre. in two other herds where genital infection was observed clinically a spreading occurred, probably because of carelessness in clinical examinations, although the possibility of an additional spreading by the respiratory route had to b ...1978208053
[antibodies against selected viruses and bedsonia in the body fluids of bovine abortions]. 1978208219
response of the respiratory tract of calves kept at controlled climatic conditions to bovine herpesvirus 1 in aerosol.seven experiments with four calves each were conducted in which the calves spent at least four days of adaptation in an environmental chamber and then were subjected to climatic stress in the form of a number of constant ambient temperature and humidity combinations. on the second day of climatic stress the calves were individually exposed to measured numbers of infectious units of bovine herpesvirus 1 (bhv1, virus of infectious bovine rhinotrachetis) in aerosol. the calves were killed seven or ...1978208734
an outbreak of the conjunctival form of infectious bovine rhinotracheitis.an outbreak of severe conjunctivitis involved approximately 30% of a dairy herd of 118 cattle. infectious bovine rhinotracheitis (ibr) virus was identified by cytopathic effects and fluorescent antibody techniques from conjunctival swabs of affected animals. the disease typically presented as a unilateral ocular disease with systemic signs of pyrexia, inappetance, decreased milk production, and some subsequent abortions.1978208813
[formation of postvaccinal immunity in infectious rhinotracheitis]. 1978209606
trisodium phosphonoformate, a new antiviral compound.trisodium phosphonoformate selectively inhibits cell-free dna polymerase activity induced by herpesvirus. the new inhibitor has an antiviral effect on herpes simplex virus types 1 and 2, pseudorables virus, and infectious bovine rhinotracheitis virus in cell culture. it has a good therapeutic activity against cutaneous herpes simplex virus infection in guinea pigs.1978210500
pneumonia in calves produced with aerosols of bovine herpesvirus 1 and pasteurella haemolytica.in each of 11 experiments, four calves were exposed first to an aerosol of bovine herpesvirus 1 (bhv1, virus of infectious bovine rhinotracheitis) and second to an aerosol of pasteurella haemolytica. the interval between aerosols was three to five days. in two other experiments, calves were exposed only to a bacterial aerosol. climate was controlled for all experiments from the day of viral exposure and for eight of the experiments it was also controlled for four to six days before the first aer ...1978210912
antiviral activity in interferon-treated bovine tracheal organ cultures.the effect of bovine interferon on the replication of infectious bovine rhinotracheitis virus and vesicular stomatitis virus in bovine tracheal organ cultures was studied. after treatment of tracheal organ cultures with interferon, inhibition of infectious bovine rhinotracheitis virus and vesicular stomatitis virus replication was observed. this tracheal organ system may be useful in determining the in vivo response to interferon for viral infections of the bovine respiratory tract.1978211089
the use of polyethylene glycol in concentration and purification of several bovine viruses.the polyethylene glycol (peg) precipitation method was used for the concentration and purification of eight bovine viruses. good results were obtained from four viruses, parainfluenza--3 virus, bovine enterovirus, bovine adenovirus, and bovine parvovirus. no satisfactory results of concentration were obtained from bovine reovirus, bovine viral diarrhea virus, and infectious bovine rhinotracheitis virus. the failure of concentration of the four viruses seems to be ascribed rather to the resuspend ...1978211444
a serological survey on the prevalence of infectious bovine rhinotracheitis in buckinghamshire, berkshire and oxfordshire.of the 2368 cattle sera from herds in buckinghamshire, berkshire and oxfordshire examined for infectious bovine rhinotracheitis antibody by an indirect haemagglutination test, 162 (6.8 per cent) proved positive. positive titres were more prevalent in older cows and they tended to show higher titres. there was little evidence of infection in the bulls tested. the percentage of positive animals in berkshire and oxfordshire was 4.7 compared with 10.5 in buckinghamshire. the infection was not known ...1978211700
experimental infectious bovine rhinotracheitis virus infections of english ferrets (mustela putorius furo l).intranasal and intraperitoneal exposure of english ferrets (mustela putorius furo l) to infectious bovine rhinotracheitis virus caused acute and chronic infections of the respiratory tract. the clinical syndrome was characterized by sneezing, coughing, and anorexia from postexposure days (ped) 3 to 7. mucopurulent exudate was observed in the posterior nares and pharyngeal area of ferrets euthanatized on ped 4 and 8. the virus was readily recovered from the turbinates, respiratory tract epitheliu ...1978211885
neural changes in recurrent infection of infectious bovine rhinotracheitis virus in calves treated with dexamethasone.recurrent infection by infectious bovine rhinotracheitis (ibr) virus was induced in calves by dexamethasone (dm) treatment (given 5 days) at 5 months after primary infection. the virus appeared in nasal secretions of the calves on the 4th day after initiation of dm treatment and continued until the 9th day. the calves were killed on the 1st, 3rd, 4th, 5th, 6th, 7th, 8th, 10th, and 11th days after dm treatment was started for examination by histopathologic and immunofluorescent antibody technique ...1978211886
identification of a herpesvirus isolated from cytomegalovirus-transformed human cells.human cells transformed by cytomegalovirus and transplanted to athymic nude mice yielded a cytopathic virus, hershey medical center virus, following prolonged in vitro passage of the tumor cells. the virus is a double-enveloped herpesvirus, is sensitive to ether, and is inhibited by iododeoxyuridine. no significant antigenic relationship to herpes simplex virus was detected using herpes simplex virus-immune sera in neutralization and immunofluorescence tests, but indirect immunofluorescence test ...1978212591
activation of endogenous type c virus in balb/c mouse cells by herpesvirus dna.several virion and nonvirion dnas were tested for the ability to activate endogenous type c virus in balb/c-derived mouse cells using the calcium precipitation technique. the dnas from all herpesviruses tested activated xenotropic type c virus synthesis. these included dnas from herpes simplex virus types 1 and 2, epstein-barr virus, human cytomegalovirus, sa8 virus, infectious bovine rhinotracheitis virus, pseudorabies virus, and herpes saimiri virus (m-dna). in contrast, dnas from vaccinia vir ...1978212761
an acute severe outbreak of infectious bovine rhinotracheitis: clinical, epidemiological, microbiological and pathological aspects. 1978214928
local and systemic cellular and antibody immune responses of cattle to infectious bovine rhinotracheitis virus vaccines administered intranassally or intramuscularly. 1978215063
[demonstration of bovine herpesvirus 1 (ibr/ipv) in cattle with gastrointestinal diseases]. 1978215117
a viral infection connected with infertility in cattle in tanzania. 1976215249
bovine respiratory viruses. 1978216248
the p 37/24 modification of the infectious bovine rhinotracheitis virus-serum neutralization test. 1978217258
mechanisms of recovery from herpesvirus infections -a review.a variety of specific immunological mechanisms have been shown to be effective at neutralizing herpesviruses or destroying herpesvirus infected cells. these include both humoral and cell mediated immune responses or combinations thereof. thus, it is genarlly accepted that humoral immunity is probably responsible for preventing reinfection whereas cellular immunity, mediated by t lymphocytes or by the interaction of antibody and fc receptor bearing cells, is more important in recovery from infect ...1978217506
[isolation of infectious bovine rhinotracheitis virus (ibr) in brazil (preliminary note)]. 1978218257
preliminary characterization of viruses isolated from cases of epididymitis and vaginitis in cattle.twelve slow-growing virus isolates propagated in tissue culture from cattle with epididymitis and vaginitis were identified as herpes viruses by virtue of their biological, physicochemical and morphological characteristics. none of the 12 virus strains proved to be serologically related to the infectious pustular vulvo-vaginitis-infectious bovine rhinotracheitis (ipv-ibr) virus, but a further 3 strains included in this study were identical with ipv-ibr virus. three of the slow-growing virus stra ...1978220578
early protection against infectious bovine rhinotracheitis with intramuscularly administered vaccine. 1975220626
the bovine herpesviruses: an overview. 1976220627
current status of ibr-ipv virus infection in bulls. 1976220628
the influence of infectious bovine rhinotracheitis virus on the foot-and-mouth disease carrier state. 1976220630
affect of cell passage on neutralizing properties of infectious bovine rhinotracheitis virus. 1977220640
serological evidence of infectious bovine rhinotracheitis, bovine virus diarrhoea and parainfluenza-3 viruses in calves in el salvador. 1979223256
[immunization effectiveness of the inactivated vaccine against infectious bovine rhinotracheitis (ibr) with an oily adjuvant].the adjuvant vaccine against infectious bovine rhinotracheitis (ibr) was tested as to its innocuousness and immunogenicity. the immunity response induced by a single or double application of different vaccine doses was evaluated according to the content of neutralization antibodies (np) in the blood serum. a direct dependence was revealed between the size of the inoculum and np content in the blood serum, with np titres of 1 : 9.3; 1 : 26.6, 1 : 80 and 1 : 149 after doubled application of 1, 2, ...1979223270
[concentration and purification of the infectious bovine rhinotracheitis virus (ibr)].various combinations of the method for the concentration and purification of the ibr virus have been tested. an easily applicable pattern is adopted with whose aid the virus is rapidly purified with a slightly reduced infectability. the pattern includes concentration of the virus through precipitation with polyethylenglycol, gel-filtration on a sepharose 4b column and ultra-centrifugation in a linear gradient of sucrose. the virus is checked electronmicroscopically, immunoelectrophoretically and ...1978223278
bovine herpesvirus 1--infection of the upper alimentary tract of cattle and its association with a severe mortality. 1978223538
diagnosis of infectious bovine rhinotracheitis by direct immunofluorescence. 1979224523
detection by direct immunofluorescence of aujeszky's disease virus in an aujeszky-ibr virus pool. 1977224684
[isolation and identification of the infectious bovine rhinotracheitis virus in a bovine fetus kidney (ibr/ipv)].the authors describe the isolation and identification of a virus from bovine fetal kidney cells maintained in culture for 30 to 45 days. the virus was characterized as a herpesvirus of the infectious bovine rhinotracheitis in cell culture by the evidence of cytopathogenic effect in bovine kidney and testis cultures and serologically by a neutralization test using rabbit anti-infectious bovine rhinotracheitis sera.1978224840
antigenic comparisons between herpesviruses isolated from fallow deer in alberta and the viruses of infectious bovine rhinotracheitis, equine rhinopneumonitis and dn-599, a non-ibr bovine herpesvirus.antigenic comparison studies of three herpesviruses isolated from fallow deer (dama dama) in alberta and herpesviruses from some domestic species were carried out by the alpha serum-virus neutralization test. complete cross neutralization was demonstrated among the deer herpesviruses and equine herpesvirus type 1.1979225575
the occurrence of infectious diseases in mixed farming of domesticated wild herbivores and domestic herivores, including camels, in kenya. i. viral diseases: a serologic survey with special reference to foot-and-mouth disease. 1979225576
demonstration of infectious bovine rhinotracheitis virus in newborn colsotrum-deprived calves with particular reference to its epizootiological significance. 1979225908
the indirect fluorescent antibody technique as a method for detecting antibodies in aborted fetuses.in this investigation the indirect fluorescent antibody technique was used to titrate antibodies in bovine sera to parainfluenza 3, infectious bovine rhinotracheitis virus and bovine viral diarrhea virus. these results were compared to those determined on the same samples by hemagglutination inhibition for parainfluenza 3 virus and serum neutralization for bovine virus diarrhea and infectious bovine rhinotracheitis virus. the results of the serological methods agreed closely. the indirect fluore ...1979226243
immune response of cattle to antigens obtained from bovine herpesvirus 1-infected tissue culture.the ability of two antigens, termed ev and cm, derived from bovine herpesvirus 1 infected cultures to produce serum-virus neutralizing antibodies has been studied in cattle. both ev and cm when inoculated with adjuvant induced significant increases in serum-virus neutralizing antibody titers. control groups inoculated in a similar manner failed to induce significant increases in serum-virus neutralizing antibody. some of the animals were vaccinated, then were bred, challenged with a virulent str ...1979226245
effect of temperature, relative humidity and medium on the aerosol stability of infectious bovine rhinotracheitis virus.aerosols of infectious bovine rhinotracheitis virus were generated with a devilbiss 40 nebulizer from eagle's minimum essential medium, nasal secretion from a noninfected calf and nasal secretion from a calf artificially infected with infectious bovine rhinotracheitis virus and aged in a rotating drum at temperatures of 6 degrees c or 32 degrees c and relative humidities of 30% or 90%. the aerosols were sampled at seven minutes after start of spraying, one hour, two hours and three hours with an ...1979227551
[isolation of infectious bovine rhinotracheitis virus from the tarsal joint of a bull (author's transl)].isolation of infectious bovine rhinotracheitis virus from the tarsal joint of a bullinfectious bovine rhinotracheitis virus was isolated from the right tarsal joint of a bull who was showing signs of a systemic viral infection. the clinical signs manifested by 16 bulls of this herd are described, the laboratory methods used are listed and the results are analysed and discussed.1979227556
observations on the epidemiology of the herpesvirus of infectous bovine rhinotracheitis/infectious pustular vulvovaginitis in wildebeest.spontaneous vulvovaginitis erupted in wildebeest (connochaetes taurinus) after betamethasone inoculation. infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (ibr/ipv) is probably a venereal disease because virgin wildebeest did not develop vulvovaginitis after betamethasone injections, nor was the virus transmitted to these virgin wildebeest and steers which were in pen contact with the affected animals. a domestic bovine heifer developed mild ipv and became a virus carrier, wh ...1979228091
interferon, antibody responses and protection induced by an intranasal infectious bovine rhinotracheitis vaccine.the interferon and antibody response induced by an intranasal infectious bovine rhinotracheitis vaccine was followed in 22 calves over a nine month period and the ability of these vaccinated calves to withstand challenge with virulent infectious bovine rhinotracheitis virus was assessed. interferon was detected two to three days post-vaccination and disappeared by the tenth day. nasal and serum antibodies appeared by day 7 and persisted for nine months. the calves challenged three days postvacci ...1979228831
persistence of infectious bovine rhinotracheitis--infectious pustular vulvovaginitis virus in the respiratory and genital tract of cattle. 1979228901
properties of human epithelioid cells established in vitro by a herpesvirus [ibrv(hmc)] isolated from cytomegalovirus-transformed human cells.infectious bovine rhinotracheitis virus [ibrv(hmc)], a double-enveloped herpesvirus, was isolated from human embryo lung fibroblasts transformed by cytomegalovirus (cmv). this agent was identified as an ibrv strain that was antigenically related to human cmv. inoculation of a primary human kidney cancer cell culture with ibrv(hmc) resulted in persistent infection and subsequent establishment of a cell line [ibrv(hmc)hkc-1]. virus-related nuclear, cytoplasmic, and cell membrane antigens were dete ...1979229291
vaccination against ibr. 1979229622
experimental infection of wildebeest with the herpesvirus of infectious bovine rhinotracheitis/infectious pustular vulvovaginitis.intravaginal inoculation of a wildebeest (connochaetes taurinus) with a wildebeest strain of the infectious bovine rhinotracheitis/infectious pustular vulvovaginitis herpesvirus induced only mild vulvovaginitis. the same virus did not produce any disease in another wildebeest exposed intranasally. a wildebeest bull which was inoculated by preputial instillation developed mild posthitis. the virus was reisolated only from the sites of inoculation. a carrier state was initiated in a wildebeest ino ...1979230363
experimental infection of eastern cottontail rabbits sylvilagus floridanus) with infectious bovine rhinotracheitis virus.experimental infection of eastern cottontail rabbits (sylvilagus floridanus) with infectious bovine rhinotracheitis virus caused acute keratoconjunctivitis and a fatal systemic infection. the clinical syndrome was characterized initially by blepharospasm and ocular discharge. the rabbits were markedly depressed on post-exposure day (ped) 5 and were dead or moribund on ped 6. the virus was readily recovered from liver and adrenal gland tissue on ped 6 and from conjunctival swabs on ped 1 to 6. hi ...1979230773
[trial of a hyperimmune serum against para-influenza 3, bovine adenovirus 1, infectious rhinotracheitis and mucosal disease].a four-valent serum was obtained by parallel hyperimmunization of cattle with live viral suspensions of parainfluenza-3, bovine adenovirus i, the virus of infectious rhinotracheitis and the mucous disease virus. the serum's neutralizing titres are between 1:1280 and 1:2560. the lasting exploitation of serum producing cattle indicates that no competition exists between the four antigens used in the process of hyperimmunization. experimental testing of the serum on calves and its application in pr ...1979231341
a field trial with a multicomponent inactivated respiratory viral vaccine.an inactivated virus vaccine containing strains of parainfluenza type 3 (pi3), bovine adenovirus type 3, reovirus type 1, bovine virus diarrhoea (bvd) and infectious bovine rhinotracheitis (ibr) viruses was tested in a group of 58 calves reared in a semi-intensive management system. following vaccination, 1/30, 14/30 and 17/30, showed significant rises in antibody titre to reovirus type 1, adenovirus type 3 and ibr respectively. none of the animals showed significant serological response to pi 3 ...1979232326
[serological diagnosis of ibr. comparative studies of cattle sera in the virus neurtalization and passive hemagglutination reactions].three hundred eighty six cattle serums were simultaneously investigated by virus neutralizing (vn) and passive hemagglutination (psh) reactions. results obtained by the two methods coincided in 94% of the sermums studied and all serums with vn antibodies had also antibodies which can be established by the psh reaction. about 6% of the positive reagents for psh reaction were negative for the vn reaction. these were serums containing early antibodies (igm) or low-titer antibodies of the igg class, ...1979232331
[isolation of the bovine herpesvirus-3 from sick calves].three herpes strains identified as herpes virus-3 were isolated in revolving test-tubes with cell cultures of nasal samples and lung parenchyma from diseased calves at the time of a respiratory enzooty. large crystalloid aggregates of herpes virus virions were observed in the nucleus and in the cytoplasma by the electron-microscopic investigation performed on infected cell cultures. the experimental infection of calves with the isolated strain produced slight symptoms of respiratory disease in s ...1979232333
[serological diagnosis of ibr. passive hemagglutination microreaction].the preparation and standardization of the ingredients for pha is described in detail. formalin treated erythrocites in a 10% concentration treated with 1:20 000 tannin were used. the antigen concentrated by ultracentrifugation properly sensibilizes the erythrocites and their titer does not change in case of its dilution up to 1:8. the non-concentrated virus antigen has a low covering potential only if it is either not diluted, or in a 1:2 dilution and sensibilizes the erythrocites to a lesser e ...1979232334
enzyme-linked immunosorbent assay for serology of infectious bovine rhinotracheitis virus infections.an enzyme-linked immunosorbent assay was developed to detect antibodies to infectious bovine rhinotracheitis virus in bovine sera. the test used viral antigen purified in a sucrose density gradient, and the antibody titers detected were up to 100 times higher than those seen in the serum neutralization test. when 250 sera were tested by those two tests, 146 were positive and 49 were negative in both tests. only 1 serum was negative in the immunoassay test and positive in the neutralization test. ...1979232505
[production and study of the immunogenic properties of a bivalent inactivated vaccine against mucosal disease (bovine viral diarrhea and infectious rhinotracheitis)].bivalent inactivated vaccine against mucous disease (md) and infectious rhinotracheitis (ir) in cattle was produced from cell cultural md and ir virus suspensions. the vaccine was concentrated on aluminium hydroxide, inactivated by ethanol and is without residual virus. saponine in final 1:1500 dilution is added as supplementary adjuvant. immunogeneity of the vaccine was tested on 10-month-old calves, which had shown full resistance against experimental infection with virulent strains of both vi ...1979232586
pathogenesis of bovine herpesvirus-1 (bhv-1) infections: interactions of the virus with peripheral bovine blood cellular components. 1979232868
leukocyte changes and interferon production in calves injected with hydrocortisone and infected with infectious bovine rhinotracheitis virus.correlations between leukocyte counts and serum interferon titers were determined in calves given hydrocortisone (hc) and infectious bovine rhinotracheitis (ibr) virus. calves were injected with either 1 mg or 3 mg of hc/kg of body weight every 8 hours for a total of 9 injections each. control calves were given placebo injections. viral inoculation was given iv 10 hours after the 1st dose of hc or placebo was given. by the time of viral inoculation, all calves injected with hc had developed neut ...1979380418
prevalence of bovine virus diarrhoea and infectious bovine rhinotracheitis antibodies in nigerian sheep and goats.neutralising antibodies to bovine virus diarrhoea virus were commoner in nigerian sheep than goats while precipitating antibodies offered an alternative but less reliable indicator of previous infection. in contrast, neutralising antibodies to infectious bovine rhinotracheitis virus were more common in goats than sheep. these findings are discussed in relation to infectivity rates in cattle and general husbandry practices.1977410130
precipitins in bovine sera to infectious bovine rhinotracheitis virus antigens. 1977410493
neural changes in recurrent genital infection of infectious bovine rhinotracheitis virus in calves treated with dexamethasone.recurrent genital infection with infectious bovine rhinotracheitis (ibr) virus was induced in calves by dexamethasone (dm) treatment 3 months after primary infection. the virus was first recovered from vaginal secretions on the 3rd day after the initiation of dm treatment; however, the virus was not recovered at all from nasal secretions or from the cerebrospinal fluid of the dm-treated calves. the significant neural changes in all recurrent infected calves were nonsuppurative poliomyelitis in t ...1979444414
use of modified live bovine herpesvirus 1 vaccines. 1979532054
neural changes in calves intranasally inoculated with two strains of infectious bovine rhinotracheitis virus. 1979541454
a bovine herpesvirus isolated from sheep.a viral agent was isolated from the trachea of a lamb that was suffering from a respiratory disorder. the physical and chemical properties of the isolates are characteristic of the herpesvirus group. it contains dna in its virion, is ether sensitive, acid labile at ph 3.0 and heat labile at 56 degrees c after five minutes. the cytopathology observed provided further evidence of a herpesvirus isolate. the neutralization of the infectivity of the isolate with antiserum to bovine herpesvirus 1 is e ...1978647461
neural changes in calves intravaginally inoculated with infectious bovine rhinotracheitis virus. 1978670437
neural changes in calves after intraconjunctival inoculation with infectious bovine rhinotracheitis virus. 1978670438
some lesions observed in calves born to cows exposed to the virus of infectious bovine rhinotracheitis in the last trimester of gestation.sixteen pregnant cows were challenged with infectious bovine rhinotracheitis virus intranasally. one had a mummified fetus, four aborted, one calf was stillborn, two live fetuses were taken at the abattoir and eight calves were born alive. of the eight born alive, five were dead by 12 days of age. four of these had the usual lesions of infectious bovine rhinotracheitis as well as lesions in the intestine and peritoneum and two of the four had a fibrinous pneumonia thought to be caused by aspirat ...1978743599
shipping fever pneumonia in yearling feedlot cattle.during each week of 1974, we surveyed, for illnesses and deaths, a continually changing population of yearling feedlot cattle that, for the year, totaled 407,000 animals. about 5.1% of the cattle sickened and, of these, 18.9% died. from the 3,943 fatalities, 1,988 necropsies were made. about 75% of the clinical diagnoses and 64% of the necropsy diagnoses were respiratory tract diseases; of the fatalities from respiratory tract diseases, 75% were attributed to shipping fever pneumonia. nearly 72% ...1976783102
pathological and microbiological observations made on spontaneous cases of acute neonatal calf diarrhea.the purpose of this report is to describe clinical signs, gross and microscopic lesions, bacteriological and immunofluorescence observations made on spontaneous cases of acute neonatal calf diarrhea (ncd) in dairy and beef herds. the following diagnostic tools were used: 1) direct smears of intestinal content, 2) escherichia coli counts, 3) aerobic bacterial cultures of the small intestine and other organs (the o serogroup and the enterotoxigenicity of the e. coli isolated was determined), 4) de ...1976793692
mycoplasma agalactiae subsp. bovis in pneumonia and arthritis of the bovine.the pneumonic lungs of 42 cattle from 26 feedlots were examined for the presence of mycoplasma, pathogenic bacteria and viruses. four animals representative of two lots failed to yield mycoplasma. one of these yielded the virus of infectious bovine rhinotracheitis and pasteurella hemolytica, the other yielded only p. p. multocida. nine animals in eight lots yielded mycoplasma sp.: five of these were m. bovirhinis, two were m. arginini and two were untypable. all of these animals yielded one or m ...1977832194
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