mekong schistosomiasis. 4. a parasitological survey of wild rodents, domestic pigs and cattle on khong island, laos. | no evidence of infection with the mekong schistosoma was found in 12 rattus exulans, 81 r. r. molliculus, and 10 bandicota savilei caught in the vicinity of and downstream from the schistosomiasis transmission focus on khong island, south laos, and examined by dissection and portal perfusion. likewise, no eggs of the mekong schistosoma were detected in faeces of 15 domestic pigs or 43 domestic cattle examined on khong island both by merthiolate-iodine-formalin concentration and by the hatching t ... | 1975 | 1166350 |
modification of ventricular fibrillation latency following coronary artery occlusion in the conscious pig. | abrupt occlusion of the left anterior descending coronary artery was performed on 45 unanesthetized farm pigs in order to evaluate the relative effects on the latency to ventricular fibrillation (vfl) of 1) adaptation of the animals to the laboratory, and 2) beta-receptor blockade by propranolol. compared to control values, vfl was greatly lengthened (i.e., vf delayed or prevented) by adaptation (p smaller than 0.01), was shortened by large (2 mg/kg) doses of racemic propranolol in unadapted ani ... | 1975 | 1167816 |
[effect of anemia on various reactions of the domestic swine due to physical exertion. i. initial values and characteristics of anemia]. | in six anaemic and six healthy pigs at rest the following values were determined:--rectal temperature, heart rate, respiratory rate, haemoglobin (hb), haematocrit (hk), total haemoglobin (thb), plasma volume, blood volume, plasma osmolarity, lactic acid and glucose content of plasma, blood ph, carbon dioxide tension and base excess. there were significant differences between anaemic and normal pigs in hb, thb, relative thb, hk, mean cell haemoglobin concentration, lactic acid content; in the ecg ... | 1975 | 1190974 |
[effect of anemia on various reactions of the domestic swine due to physical exertion. 2. components of cardiovascular function and body temperature]. | the following measurements were made in six anaemic and six healthy pigs during and after physical exertion on a belt moving at 70 m/min for 10 minutes at environmental temperature of 22-24 degrees c and relative humidity of 55-65%:--rectal temperature (rt), heart rate, total haemoglobin, plasma volume (pv), blood volume (bv) and plasma osmolarity (po). the increase: in rt and po, heart rate during exercise, respiratory rate after exercise, and the fall in pv and bv during exercise as well as ch ... | 1975 | 1190975 |
[effect of anemia on various reactions of the domestic swine due to physical exertion. 3. changes in plasma glucose and lactic acid concentrations]. | six anaemic and six healthy pigs were exercised for ten minutes on a belt moving at 78 m/min. initial blood glucose values in healthy pigs averaged 71.2 mg/100 ml, and they changed very little during and after exercise. initial values were similar in anaemic pigs (70.7 mg/100 ml), but they increased continuously, during exercise, reaching a peak of 157.4 mg/100 ml one minute after the end of exercise. blood lactic acid increased from 1152 to 2463 mmol/litre in healthy pigs during the first minut ... | 1975 | 1190976 |
[effect of anemia on various reactions of domestic swine due to physical exertion. 4. changes of serum acid-base equilibrium]. | carbon dioxide tension, ph and the excess of base were determined in blood samples obtained from the posterior vena cava of six healthy and six anaemic pigs subjected to ten minutes of exercise on a belt moving at 78 m/min at 22-24 degrees c and relative humidity of 55-65%. the fall in these values during physical exertion was greater in anaemic than in healthy pigs. the roles of buffering capacity and rise in body temperature, and the relationship between blood lactic acid and base excess were ... | 1975 | 1190977 |
[evaluation of blood glucose concentration during exertion. 6. effect of anemia on the glucose regulation capacity of domestic swine in standardized running exercise]. | individual mean blood glucose values and the scatter of individual values were determined in six healthy and six anaemic pigs before, during and after ten minutes of exercise on a belt moving at 78 m/min (environmental temperature 22-24 degrees c, relative humidity 55-65%). the glucose regulatory capacity of anaemic pigs was inferior to that of healthy pigs. blood glucose regulation was related to haemoglobin content and to the increase in rectal temperature during exercise. | 1975 | 1190980 |
physiological aspects of sperm transport in the domestic pig, sus scrofa. i. semen deposition and cell transport. | | 1975 | 1192167 |
14c-glucose and 35s-metabolism of pig epiphysial cartilage and its variations after osteotomy. | on in vitro incubation of articular and epiphysial cartilage of the ulna of the domestic pig 70 to 80 per cent of [u-14c] glucose was metabolised to 14c-lactate, but cartilage of the epiphysial plate produced up to five times as much 14c-co2 as articular cartilage, and the specific radioactivity of 14c(or 35s)-chondroitin 4(6)-sulphate isolated from epiphysial cartilage (following 35s-sulphate incorporation) was about twice as high as that of articular cartilage. six weeks after an osteotomy on ... | 1975 | 1194320 |
experimental phomopsis leptostromiformis mycotoxicosis of pigs. | the susceptibility of the domestic pig to intoxication by the causative mycotoxin of lupinosis was established experimentally. the symptomatology and pathology of the disease produced by the administration of toxic cultures of the fungus, phomopsis leptostromiformis (kühn) bubák ex lind to pigs are described. the toxin induced severe loss of weight and, in many cases, posterior paresis or paralysis. the principal gross lesions were generalised icterus, orange-red discoloration of the liver, neph ... | 1975 | 1195271 |
[lactic acid content of blood plasma in domestic swine of various breeds during physical exertion]. | lactic acid was determined by an enzymic method in plasma samples taken from 20 pigs of the german edelschwein, german landrace, german saddleback and edelschwein/landrace crosses before, during and after being made to run on a band moving at 1.3 metres/second for ten minutes, at 10 degrees c and relative humidity of 65-75%. a special method was used to assess the degree of exertion. the lactic acid curve showed that edelschwein and german saddlebacks had a low regulatory capacity while german l ... | 1975 | 1200746 |
[effect of the type of management and training on heart rate, rectal temperature and respiration rate of domestic swine during physical exertion]. | 29 pigs (meat type of german landrace) were kept in groups in a confined space (0.48 m2 a head; group e), in a normal area (1.2 m2 a head; group n) or in a normal area plus daily exercise (group l). after having been kept under these conditions for specified periods, the pigs were made to run on a band moving at 1.1 metres a second for 2 km. during exercise the heart rate increased to 275 beats a minute in group e and only 180 in group l. in group l the recovery pulse rate was greater and the ab ... | 1975 | 1200748 |
testosterone levels in early fetal testes of domestic pigs. | | 1975 | 1218196 |
[histometric findings in the adrenals of the domestic pig with reference to constitutional defects]. | the piétrain pigs are significant different from the german landrace and the edelschwein in the histometrical parameters of the adrenal glands like cortex and medulla part, height of the cortex regions, part of adrenaline and noradrenaline producing cells. the weight of their adrenal glands is less than in the other races but their part of zona fasciculata and of adrenaline producing cells is comparably high. these findings let expect distinct reactions on stressors. there are no hints on insuff ... | 1975 | 1229244 |
neonatal behavior and nutrition-related mortality in domestic swine. | | 1976 | 1248968 |
toxicological studies on azapropazone. | the toxicity of azapropazone, a non-steroidal anti-inflammatory analgesic compound was studied in mice, rats, hamsters, guinea pigs, rabbits, cats, mongrel and beagle dogs, domestic pigs, rhesus monkeys, cynomolgus monkeys and baboons in experiments which ranged from acute, single-dose studies up to treatment periods of 1 year. the beagle dog was found to be especially sensitive to gastro-intestinal ulceration from azapropazone and this contrasted with the marked lack of gastro-intestinal hazard ... | 1976 | 1261299 |
arbovirus infections in sarawak: the role of the domestic pig. | the possible role of pigs as arbovirus maintenance hosts and their importance as amplifier hosts was studied. blood samples from 464 pigs of all ages collected in 1962 and 1964 were tested against 10 arboviruses. antibodies to japanese encephalitis and getah viruses were particularly prevalent and their calculated monthly infection rates were 19-5% and 13-3% respectively. in 1969, 447 pigs were bled monthly throughout the year and the infection rates for japanese encephalitis virus were calculat ... | 1976 | 1265821 |
the effect of clobetasone butyrate and other topical steroids on skin thickness of the domestic pig. | a new glucocorticoid, clobetasone butyrate, has been shown in patients to have good topical anti-inflammatory activity and a minimal effect on hypothalamic-pituitary-adrenal function. among a group of topically active corticosteroids, compared in a controlled study in the domestic pig, clobetasone butyrate is shown to cause less epidermal thinning than any of the others except only 1% hydrocortisone. this evidence of a lesser atrophogenic effect may indicate further dissociation of unwanted from ... | 1976 | 1268065 |
experimentally induced steroid atrophy in the domestic pig and man. | a histological method of ranking topical steroid preparations according to the degree of epidermal thinning they cause in pig skin has been shown to be applicable to human skin. a 0-05% ointment of the new compound, clobetasone butyrate (molivate), has been shown to cause less thinning than either fluocinolone acetonide 0-025% (synalar) or flurandrenolone 0-0125% (haelan) when applied without the use of occlusive dressings for 3 weeks to the human forearm. | 1976 | 1268070 |
skin tension lines in the domestic pig. | the skin tension lines of the domestic pig have been mapped. with a 6mm punch biopsy, local relative skin forces can be determined. the influence of various factors (such as age, fat deposition, gascial attachments, and previous scarring) on the direction of the skin tension lines is discussed. | 1976 | 1273151 |
isoenzymatic pattern and structure of glutamate dehydrogenase from ascaris suum. | the isoenzymatic pattern of glutamate dehydrogenase (gdh) has been described for ascaris suum a parasite of sus scrofa domestica. only one band of activity has been revealed, suggesting a monomorphic condition for this enzyme. also, the structure of gdh has been assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and silver staining. only one subunit was present with a molecular weight of about 55,000. a hexameric structure for gdh of a. suum is suggested. | 1992 | 1293199 |
ontogenetic changes in porcine adrenocortical adrenocorticotropic hormone receptors. | 1. binding of [125i]acth(1-38) analog to adrenal receptors was measured in fetal pigs (sus domesticus) at 15-day intervals from midpregnancy (60 days) to near term (105 days; pregnancy length 114 days). 2. binding was greatest at day 60 (0.42 +/- 0.03 fmol/200 micrograms protein or 0.50 +/- 0.08 fmol/50 micrograms dna), and least at day 105 (0.13 +/- 0.03 fmol/200 micrograms protein or 0.16 +/- 0.04 fmol/50 micrograms dna). total adrenal binding was constant (0.61 +/- 0.02 fmol/paired adrenals). ... | 1992 | 1316295 |
somatostatin- and neuropeptide y-like immunoreactivity in the dentate area, hippocampus, and subiculum of the domestic pig. | with the principal aim of providing baseline observations for future experimental studies, the distribution of somatostatin-like and neuropeptide y-like immunoreactivities is described in the dentate area, hippocampus, and subiculum of the domestic pig (sus scrofa domesticus) and compared with the distribution described in other mammals. intensely stained somatostatin-like immunoreactive nerve cell bodies were present throughout the region, with highest densities in the dentate hilus, stratum ra ... | 1992 | 1355497 |
tyrosine hydroxylase and acetylcholinesterase in the domestic pig mesencephalon: an immunocytochemical and histochemical study. | the mesencephalon of the young domestic pig was studied by tyrosine hydroxylase (th) immunocytochemistry and acetylcholinesterase (ache) histochemistry with focus on the substantia nigra (sn), the ventral tegmental area (vta), and related areas. the purpose was to obtain information on the organization of the mesencephalic, th immunoreactive (th-i), and dopaminergic areas of the pig, in order to provide the necessary background for the possible use of the pig as an alternative large animal exper ... | 1992 | 1355778 |
the gene for dominant white color in the pig is closely linked to alb and pdgrfra on chromosome 8. | white is a widespread coat color among domestic pig breeds and is controlled by an autosomal dominant gene i. the segregation of this gene was analyzed in a reference pedigree for gene mapping developed by crossing the european wild pig and a large white domestic breed. the gene for dominant white color was shown to be closely linked to the genes for albumin (alb) and platelet-derived growth factor receptor alpha (pdgfra) on chromosome 8. an unexpected phenotype with patches of colored and white ... | 1992 | 1362182 |
immunosuppressive macrolides of the type fk 506: a novel class of topical agents for treatment of skin diseases? | the immunosuppressive macrolide antibiotics fk 506 and rapamycin were tested for topical activity in experimental allergic contact dermatitis of farm pigs. this species was used because pig skin, in comparison to rodent skin, resembles human skin more closely. for comparison, cyclosporine a (cya), which is orally but not topically active in patients with skin disease, dexamethasone, and clobetasol propionate were used. treatment was performed twice, 30 min and 6 h after elicitation of challenge ... | 1992 | 1375617 |
intramural methotrexate therapy for the prevention of neointimal thickening after balloon angioplasty. | the study was performed to test the hypothesis that high local, intramural concentrations of antineoplastic agents at the site of balloon injury inhibit vascular smooth muscle cell proliferation without systemic toxicity. | 1992 | 1386089 |
characterization and pathogenicity for pigs of a hog cholera virus strain isolated from wild boars. | one hog cholera virus strain isolated from an outbreak of the disease in a wild boar breeding herd in brittany (france) in 1990 has been characterized with a panel of monoclonal antibodies to hog cholera virus and ruminant pestiviruses: the strain was found to be indistinguishable from that of other domestic pig isolates. the pathogenicity of the strain to domestic pigs was evaluated by infecting intranasally, intramuscularly and by contact 17 specific pathogen-free 6-week- and 12-week-old pigs. ... | 1992 | 1387299 |
effect of intra-abdominal pressure on abdominal wall blood flow. | adverse effects of increased intra-abdominal pressure (iap) on cardiac, pulmonary, and renal function have been well described. abdominal wound healing complications seen in the massively injured patient may also be associated with iap. the effects of iap on abdominal wall blood flow, however, have not been documented. this study examines rectus sheath (rs) blood flow in a porcine model of increased iap. seven domestic swine were anesthetized with pentobarbital and maintained with isoflurane. sw ... | 1992 | 1388005 |
the influence of intensive hyperbaric oxygen therapy on skin flap survival in a swine model. | conflicting reports exist regarding the influence of hyperbaric oxygen therapy on random skin flap survival. the present investigation sought to demonstrate enhanced survival of experimental random skin flaps in swine using an intensive and tapering hyperbaric oxygen therapy regimen that would have direct application in human clinical trials. random cutaneous flaps were surgically constructed on 12 domestic pigs. flaps were designed to obtain a predictable length of necrosis. six pigs did not un ... | 1992 | 1389055 |
a chromosome 1-specific dna library from the domestic pig (sus scrofa domestica). | chromosomes were prepared from lymphocytes of a male domestic pig and flow-sorted on a dual-laser facs. twenty spots were observed, corresponding to the known pig karyotype of 18 pairs of autosomes plus the x and y. dna was isolated from 10,000 copies of the presumed chromosome 1 spot, restricted with sau3a, ligated into the vector pgem4z, and pcr amplified using universal primers; the products were then re-ligated into puc18. after transformation into escherichia coli, 210,000 independent colon ... | 1992 | 1395721 |
the gene map of the pig (sus scrofa domestica l.): a review. | a review of the present status of the porcine gene map is given with references. a total of 84 loci have now been studied, and genes have been assigned to 17 chromosomes. among them, six chromosomes are defined by only one marker. no loci have been attributed yet to three chromosomes. | 1992 | 1395726 |
percutaneous obliteration of the cystic duct with a holmium:yttrium-aluminum-garnet laser: results of in vitro and animal experiments. | the purpose of this study was to investigate the feasibility of using a holmium:yttrium-aluminum-garnet laser to permanently occlude the cystic duct in order to isolate the gallbladder from the biliary-enteric circulation and prevent gallstone formation. | 1992 | 1414812 |
the transovarial transmission of babesia trautmanni by rhipicephalus simus to domestic pigs. | rhipicephalus simus was, for the first time, experimentally proven to be a transovarial vector of babesia trautmanni of domestic pigs. the nymphal and adult progeny of experimentally infected female ticks transmitted the infection to 2 susceptible splenectomized pigs. features of the infection included a prepatent period of 6-8 days post-tick infestation, a febrile reaction for 3 days and a maximum parasitaemia score of 15 (more than 6 parasites per 300 red blood cells). other clinical signs in ... | 1992 | 1437025 |
extracorporeal circulation as an alternative to open-chest cardiac compression for cardiac resuscitation. | open-chest direct cardiac compression represents a more potent but highly invasive option for cardiac resuscitation when conventional techniques of closed-chest cardiac resuscitation fail after prolonged cardiac arrest. we postulated that venoarterial extracorporeal circulation might be a more effective intervention with less trauma. in the setting of human cardiac resuscitation, however, controlled studies would be limited by strategic constraints. accordingly, the effectiveness of open-chest c ... | 1992 | 1446500 |
acute and chronic morphine administration in swine. | functional responses to acute and chronic morphine administration in domestic swine were examined and correlated with pharmacokinetic profiles. acute effects of morphine sulfate were monitored in pigs for 24 h and the chronic actions of morphine alkaloid were monitored for 21 days. serum morphine levels, nociception, locomotor activity, respiratory rate, body temperature, and body weight were monitored during all studies. to assess nociception in a large laboratory animal, a portable thermal sti ... | 1992 | 1448475 |
intracellular axonemes within ciliated cells in the tracheal epithelium of domestic pigs. | extended aggregates of intracellular axonemal derivatives can be seen within the apical cytoplasm of ciliated cells of apparently healthy domestic pigs. such alterations were observed in 15 out of 20 animals. complete (9 + 2) or incomplete (8 + 2 - 5 + 2) intracellular axonemes were found which sometimes arose from mature, irregularly arranged kinetosomes. in addition, bundles of single microtubules and microtubular pairs were found. in previous investigations on the ciliated epithelium of diffe ... | 1992 | 1452480 |
does a single bout of exercise cause adaptation of amino acid metabolism in pigs? | amino acid responses to exercise stress in well-trained racehorses and human athletes are well characterised, but the knowledge of amino acid metabolism during and after exercise in inactive animal species is limited. to study this, plasma amino acid concentrations were measured in previously unexercised pigs which performed two exercise tests on a treadmill with an interval of one week. in general, the changes in amino acids were more pronounced after the second than after the first exercise bo ... | 1992 | 1465506 |
bite-force development, metabolic and circulatory response to electrical stimulation in the canine and porcine masseter muscles. | the development of fatigue was investigated by electrical stimulation in 15 domestic pigs (1 yr old, 70-90 kg body weight) and seven adult dogs (3 yr old, 45 kg body weight). after anaesthesia, silver electrodes were implanted in the anterior and posterior parts of the right masseter muscles. the contralateral muscle was used as control. the bite force was measured. muscle biopsies were obtained from the anterior, central and posterior parts, and were immediately frozen in liquid nitrogen. a flu ... | 1992 | 1471960 |
seasonal abundance of lutzomyia shannoni (diptera: psychodidae) on ossabaw island, georgia. | population dynamics of lutzomyia shannoni were monitored from april 1986 through december 1987 on ossabaw island, ga. most (99%) of the 19,788 adult sand flies were collected in light traps supplemented with dry ice; less than or equal to 1% were aspirated from diurnal resting sites. adult sand flies first appeared in april and were followed by peaks of abundance during may 1986, and may and july 1987. numbers of adults captured fell rapidly in october and november 1986 and in september and octo ... | 1992 | 1495026 |
numerical variation of nucleolar organizer regions after silver staining in domestic and wild suidae (mammalia). | selective silver staining was used to investigate the cellular distribution of numbers of nucleolar organizer regions (nors) in domestic pigs (sus scrofa) of eight different breeds, the european wild boar (s. scrofa scrofa), indonesian wild boar (s. scrofa vittatus), javan warty pig (s. verrucosus), sulawesi warty pig (s. celebensis), and pigmy hog (s. salvanius). in the domestic pig as well as in the wild (sub)species of sus, actively transcribing ribosomal rna genes were found to be present in ... | 1992 | 1503258 |
ex vivo investigation of blood monocyte and platelet behaviour in pigs maintained on an atherogenic diet. | domestic pigs aged 4 months were fed for 16 weeks an atherogenic diet rich in cholesterol and saturated fatty acid. the increase of plasma cholesterol and triacylglycerol levels was found to be accompanied by a significant increase in the number of blood monocytes and platelets when compared to control animals. furthermore, the atherogenic diet produced a small but significant reduction in the blood monocyte phagocytic capacity and adhesion to plastic surface. no significant differences between ... | 1992 | 1504579 |
right heart function during prosthetic left ventricular assistance in a porcine model of congestive heart failure. | a left ventricular assist device was used to produce a 90% reduction in peak systolic left ventricular pressure in pigs with congestive heart failure, and the resultant effects on right ventricular function were determined. initially, eight farm pigs underwent rapid ventricular pacing at 230 beats/min for 7 days to produce congestive heart failure. when compared with an independent series of normal pigs, cardiac output in the paced animals was 33.3% less (2.2 +/- 0.2 versus 3.3 +/- 0.5 l/min; p ... | 1992 | 1513147 |
[reconstruction-plasty of iatrogenic choledochal stenoses using human pericardium. an experimental study in the domestic pig]. | the effect of human pericardial patch plastic for reconstruction of iatrogenic common bile duct stenosis was investigated in experiments performed in pigs. all patches (n = 8) were overgrown with immature biliary epithelium detectable on light and electron microscopy within 6 weeks. no restenosis nor any fistula developed during this observation period. liver function tests, especially bilirubin, were not suitable parameters for the detection of biliary obstruction (preoperative value 0.38 +/- 0 ... | 1992 | 1514292 |
blockade of protein c activation reduces microvascular surgical blood loss. | protein c is a natural anticoagulant glycoprotein which prevents intravascular clot formation. protein c functions as an anticoagulant when converted to an active serine protease (activated protein c). activated protein c is formed at the site of the endothelial injury in response to blood clotting and helps limit the size of blood clots. we tested the hypothesis that by temporarily blocking the activation of intrinsic protein c, we could reduce subsequent surgical blood loss from a microvascula ... | 1992 | 1528031 |
[a 2-year study of the incidence of campylobacteriasis in the district of liptovský mikulás]. | the authors investigated the incidence of campylobacteriosis in the population of the district during 1989-1990. during the above period by cultivation 723 cases of the disease were confirmed, i.e. the incidence in 1989 was 319, the number of cases 428, in 1990 the corresponding figures were 220 and 295. the incidence of campylobacteriosis is significantly higher than that of other investigated bacterial diseases. the authors did not find a significant difference in the incidence of campylobacte ... | 1992 | 1534519 |
[the demonstration of cellular reactions in the temporomandibular condylar cartilage by nmr microscopy. the basic research for high-resolution nmr tomography of the temporomandibular joint]. | the regional resolution of modern imaging methods is not good enough to clinically objectify changes to the cartilage of the temporomandibular joint, for example in functional orthodontic treatment. nmr microscopic studies of an intact temporomandibular joint preparation were done experimentally in the domestic pig on the basis of 1h-nmr relaxometric measurements in specimens of condylar cartilage. we succeeded in representing the cartilage of the temporomandibular joint down to the cellular lev ... | 1992 | 1551628 |
[the growth reaction of the temporomandibular cartilage to biomechanical stimuli and its significance for functional orthodontics--the results of experimental animal and biophysical research]. | adaptive changes in the condylar cartilage of the temporomandibular joint resulting from an experimentally induced lateral occlusal disturbance, were examined in ten juvenile domestic pigs. for the first time, in addition to histological methods for the objectification of changes in the matrix, biophysical methods such as 1h-nmr spectroscopy, electrical impedance spectroscopy and the measurement of mechanically induced potentials were used. changes in the water-binding behavior of the matrix of ... | 1992 | 1551629 |
[is feeding of green silage in areas with hog cholera in wild boar a danger for domestic swine herds? experimental study]. | in an experimental study we tested the survival of hog cholera virus (hcv) contained in pieces of muscular tissue and organs from experimentally infected swine after incubation in silage. in big (diameter greater than 20 cm) muscular pieces hcv survived even in excellent mineral acid silage (ph 3.8-4.0) after a storage of 5 months. on the other hand in smaller parts (musculature tissue, organs less than 20 cm diameter) we never found virulent hcv after 3 months of incubation. independent of the ... | 1992 | 1575668 |
natural infections of asian taenia saginata metacestodes in the livers of korean domestic pigs. | the taenia species in east asia, hitherto identified as taenia saginata, has been recognized as differing from the classical descriptions of life cycles and was recently named taenia saginata taiwanensis (tentatively until 1992). major differences between t. saginata and the newly recognized asian t. saginata are their intermediate hosts and the infected tissues. asian t. saginata metacestodes are found in the livers of pigs rather than in the muscles of cattle. in this study, we observed the na ... | 1992 | 1576109 |
experimental human infection with asian taenia saginata metacestodes obtained from naturally infected korean domestic pigs. | the infectivity of metacestodes of asian taenia saginata, now tentatively called taenia saginata taiwanensis, in human host was confirmed. the metacestodes used in experimental infection were collected from the livers of naturally infected domestic pigs at an abattoir in cheongju city, korea. the first gravid proglottid was spontaneously discharged 76 days after infection. two worms were recovered two years later by chemotherapy. the scolex was unarmed. the number of main uterine branches, varyi ... | 1992 | 1576110 |
abnormalities in the regulation of blood platelet free cytosolic calcium in malignant hyperthermia. ii. pig platelets. | since 1966 the domestic pig has served as the animal model in malignant hyperthermia (mh) research [1]. the use of genetically well-defined pigs rendered it possible to test the method for diagnosing mh-susceptibility of patients presented in the preceding paper. thus, the effect of halothane on intracellular calcium movements was studied in quin-2- and chlorotetracycline-loaded pig platelets. in 'ca(2+)-free' suspensions the resting level of free cytosolic ca2+ was about 60 nm. in contrast to t ... | 1992 | 1576636 |
distribution of vasopressin and oxytocin cells and fibres in the hypothalamus of the domestic pig (sus scrofa). | the distribution of vasopressin and oxytocin cells and fibres was studied in the pig hypothalamus by means of monoclonal antibodies, in order to prevent the non-specific staining that is characteristic for the pig. the nucleus circularis is described for the first time in the pig hypothalamus and consists of both oxytocin and vasopressin containing cell bodies. a cell group, characteristic for the pig and horse, lateral and caudal from the vascular organ of the lamina terminalis, was found to be ... | 1992 | 1583158 |
alanine, glutamate, and ammonia exchanges in acutely ischemic swine myocardium. | coronary artery disease causes an increase in glutamate uptake and alanine output by the heart. we assessed the effects of acute myocardial ischemia on alanine and glutamate exchange and ammonia production in 10 anesthetized open-chest domestic swine (46.9 +/- 0.7 kg). coronary blood flow was controlled through an extracorporal perfusion circuit. after a nonischemic control period (aerobic) the blood flow in the left anterior descending coronary artery was reduced by 60%. arterial and anterior i ... | 1992 | 1590740 |
helminth parasites of wild boar, sus scrofa, in iran. | fifty-seven wild boars (sus scrofa) from protected regions of iran were examined for helminths. sixteen species of helminths were collected; there were ten nematodes, one acanthocephalan, two trematodes and three larval cestodes. new host and distribution records were established for all helminths except of taenia solium cysticerci. wild boar shared nine of these helminths with domestic pigs, six with ruminants and three with human beings in iran. metastrongylus pudendotectus and m. salmi are re ... | 1992 | 1602589 |
occlusion of the pig superior sagittal sinus, bridging and cortical veins: multistep evolution of sinus-vein thrombosis. | cerebral sinus-vein thrombosis may lead to severe hemodynamic changes, elevated intracranial pressure (icp), and brain edema. it is supposed that progression of the thrombus from the sinus into bridging and cortical veins plays a key role in the development of these pathophysiological changes, but this hypothesis lacks experimental proof. the aim of this study, using a novel animal model of sinus-vein thrombosis, was to evaluate the effects of a standardized occlusion of the superior sagittal si ... | 1992 | 1607953 |
pandemic influenza: a zoonosis? | in the last two decades, influenza a viruses have been found to occur throughout the animal kingdom, mainly in birds, notably aquatic ones, in which infection is largely intestinal, waterborne, and asymptomatic. the domestic duck of southern china, raised in countless numbers all year round mainly as an adjunct to rice farming, is the principal host of influenza a viruses. studies based on hong kong h3n2 viruses from southern china suggest that pandemic strains originate from the domestic duck t ... | 1992 | 1609163 |
cloning and characterization of highly polymorphic porcine microsatellites. | a size-fractionated (200-400 bp) porcine genomic library was screened with the dinucleotide motifs (tg)n and (tc)n. the number of tg- and tc-positive clones was 83 and four, respectively, implying that the former motif is more frequent in the porcine genome, as previously reported in other species. twenty-six tg-clones were sequenced, and the number of repeats varied between 16 and 42 with different compositions of the repetitive sequences; 17 clones had a perfect stretch of tg-repeats, four had ... | 1992 | 1624765 |
evaluation of an enzyme-linked immunosorbent assay for diagnosis of trichinellosis in swine. | experimental and field trials were conducted to evaluate an elisa for its ability to detect trichinella-infected domestic swine and to compare elisa results with muscle-digestion test results. the elisa used was a commercial double-antibody kit, containing an excretory-secretory antigen, and was evaluated principally for epidemiologic use. experimentally induced infection in swine (4 groups of 3 pigs each; inoculated with 0, 50, 500 or 5,000 larvae) was detected as early as postinoculation week ... | 1992 | 1626777 |
biological characterization of trichinella isolates from various host species and geographical regions. | forty isolates of trichinella collected from 5 continents were compared for 7 biological characters: newborn larvae produced per female worm cultured in vitro at the seventh, eighth, and ninth day postinfection, host muscle nurse cell development time, reproductive capacity index in rats and chickens, and resistance of muscle larvae to freezing. the isolates also were compared by analyses of an environmental character of the location from which they were isolated: the isotherms for january and j ... | 1992 | 1635023 |
taxonomic revision of the genus trichinella. | the analysis of genetic, biochemical, and biological data on about 300 trichinella isolates, reported in the literature, allows a taxonomic revision of this genus. we propose the recognition of 5 sibling species, trichinella spiralis (owen, 1835) sensu stricto; trichinella nativa britov and boev, 1972; trichinella pseudospiralis garkavi, 1972; trichinella nelsoni britov and boev, 1972 sensu stricto; and trichinella britovi n. sp., on the basis of biochemical and biological characteristics. trich ... | 1992 | 1635024 |
physical examination of swine. | swine may be examined to evaluate a disease state or a lowered economic performance or as a herd health consultation. as much of the examination as possible should be performed without handling the animal. a thorough history, evaluation of herd records, environmental examination, and herd examination should be performed prior to the evaluation of an individual animal. all necessary equipment should be available when starting the individual examination. the animals is then restrained and examined ... | 1992 | 1643555 |
free-running rhythms of adrenocorticotropic hormone (acth), cortisol and melatonin in pigs. | in the domestic pig, a circadian rhythm of plasma cortisol occurs, with greatest concentrations in the morning and lowest concentrations in the afternoon. however, photic entrainment of the rhythms of acth and melatonin in pigs have not been defined clearly. this experiment was designed to evaluate free-running rhythms of acth, cortisol and melatonin in pigs housed in constant light (ll) and constant darkness (dd). twelve crossbred barrows, maintained under ambient photoperiod, were catheterized ... | 1991 | 1649029 |
monitoring japanese encephalitis virus activity using domestic sentinel pigs in mandya district, karnataka state (india). | domestic pigs were used as sentinels in mandya district (karnataka state) in india during 1984 to 1986 to monitor the activity of japanese encephalitis (je) virus in nature. out of 213 sentinel pigs studied in 11 localities, 44 pigs placed at 5 localities showed seroconversion to japanese encephalitis virus. a pig mosquito cycle, operating throughout the year appears to be one of the maintenance mechanisms of the virus in the study area in addition to the bird-mosquito cycle. | 1991 | 1657767 |
species-dependent differences of high affinity [3h]paf-binding to platelets from humans and pigs and its inhibition by selected antagonists. | the sensitivity of blood platelets towards paf (1-o-alkyl-2-o-acetyl-sn-glycero-3-phosphocholine) strongly varies with species and is primarily responsible for different pathophysiological effects after its administration to experimental animals. platelets from domestic pigs were shown to possess one single class of high-affinity paf-binding sites. receptor density and sensitivity of pig platelets towards paf were distinctly higher than those from humans. preincubation of platelets from both spe ... | 1991 | 1662546 |
human vntr sequences in porcine htf-islands. | mapping of complex genomes has been influenced substantially by the isolation of locus-specific, but repetitive dna elements known as vntrs. since a high gc-content is characteristic of most of these elements one might expect them to be clustered at least partially in cpg-islands. to address this question we have constructed a porcine liver dna noti-linkage library in puc18 using isolated htf-islands. hpaii tiny fragments ranging from less than 100 bp to 1 kb in length were randomly selected and ... | 1991 | 1678358 |
protective property of azelastine against histamine challenge of rhinal mucosa in domestic pigs. | in anaesthetized domestic pigs a filter paper sampling technique was applied to estimate basal and histamine induced nasal secretion. histamine (0.2 mg/nostril) increased secretion more than twofold, a dose of 2 mg/nostril more than 10 fold. intranasally instilled azelastine (a-5610, cas 58581-89-8) prevented this histamine induced rhinorrhea without reduction of basal secretion. the protective effect remained for more than 2 h even when histamine challenge was repeated. | 1991 | 1686828 |
pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion. | the myocardial availability of the beta 1-selective blocker metoprolol was compared following standard intravenous (i.v.) administration and after coronary venous retroinfusion. thirteen open-chest farm pigs were subjected to 90-min occlusion of the left anterior descending coronary artery. in six of these pigs, metoprolol was administered as an i.v. injection while 7 pigs received the drug retrogradely into the coronary vein. the time of administration was 5 min. in both groups, metoprolol was ... | 1990 | 1688978 |
[cytoarchitecture and topography of the ventromedial hypothalamic nuclei of swine (sus scrofa domestica)]. | the topography and cytoarchitecture of nc. hypothalamicus ventromedialis, nc. hypothalamicus dorsomedialis and nc. infundibularis were descripted in the pig. the nc. hypothalamicus ventromedialis is the dominant nucleus in the tuber cinereum. the rostral pole lies caudal to the nc. hypothalamicus anterior. its caudal pole is bounded by the nc. premamillaris and the nc. hypothalamicus ventrolateralis. scattered neurons separate the nc. hypothalamicus ventromedialis dorsal from the nc. hypothalami ... | 1990 | 1707075 |
histochemical demonstration of zinc in the hippocampal region of the domestic pig: ii. subiculum and hippocampus. | the distribution of zinc has been described in two areas of the hippocampal region of the domestic pig, viz., the subiculum and the hippocampus. zinc was demonstrated histochemically according to the neo-timm method, a modification of the sulphide-silver procedure. in each of the examined areas the staining displayed a distinctly stratified pattern which has been compared in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, resulting in a combined chemo- and cytoar ... | 1991 | 1709650 |
distribution of substance p, gnrh, met-enkephalin in the central nervous system of the pig. | the distribution of substance p (sp), gonadotropin releasing hormone (gnrh) and met-enkephalin in the brain and spinal cord of the domestic pig is described for the first time. the levels of sp, gnrh and met-enkephalin were measured by specific radioimmunoassays in various regions of the brain and spinal cord of the pig. substance p and met-enkephalin are widely distributed within the central nervous system of the pig. high levels of sp were found in the preoptic area (poa), suprachiasmatic area ... | 1991 | 1714337 |
[homology between the lpm system of allotypes in the american mink and the gp system of allotypes in the domestic pig]. | the 5 alpha-macroglobulin allotypes alpha m1, alpha m2, alpha m3, alpha m4 and alpha m5 were identified in pig. the alpha m1 allotype was reported as a marker of pig alpha-macroglobulin, the latter being homologous to alpha 2-macroglobulins in human and in mink. the allotypes alpha m2-alpha m5 were specified as markers of the second isotypical variant of pig alpha-macroglobulins, which was homologous to mink lpm macroglobulin (alpha 1m). as seen from data obtained by international comparative te ... | 1991 | 1714847 |
localization of calmodulin in epidermis and skin glands: a comparative immunohistological investigation in different vertebrate species. | the study deals with the immunolocalization of calmodulin-reactive epithelial cells in different vertebrates (tinca tinca, ambystoma mexicanum, xenopus laevis, rana ridibunda, columba domestica, sus scrofa domestica, homo sapiens sapiens). the immunoperoxidase technique was performed on acetone fixed frozen sections using monoclonal (bf8) and polyclonal (acam) anti-calmodulin antibodies. we were able to differentiate 2 major types of staining patterns: 1. a more superficial epidermal staining in ... | 1991 | 1718122 |
effects of high arterial oxygen tension on function, blood flow distribution, and metabolism in ischemic myocardium. | although oxygen inhalation therapy has long been used in the treatment of acute myocardial ischemia, experimental evidence that increased arterial po2 has any beneficial effect in the absence of hypoxemia is equivocal. in this study, we used a swine model of subendocardial myocardial ischemia to determine the effects of arterial hyperoxia on regional myocardial contractile function (sonomicrometry), myocardial blood flow distribution (microspheres), and regional myocardial glycolytic metabolism ... | 1992 | 1735173 |
effects of atherogenic diet on young farm pigs. | this study was designed to assess the usefulness of young farm pigs as an experimental model for hypercholesterolemia. in order to test this, we investigated both serologic and electrocardiographic effects of atherogenic diet. four-week-old pigs were fed an atherogenic diet for 8 weeks. no arrhythmia was observed on ecg in all animals. there were no significant difference between control and atherogenic diet group on the values of ecg parameters. however, plasma lipids values of atherogenic diet ... | 1992 | 1740169 |
electron microscopical demonstration of thiols and disulphides in the porcine epidermis. | this study describes the electron microscopical distribution of free thiols and disulphides in the epidermis of the domestic pig and the wild boar, as compared to light microscopical histochemistry. with the silver methenamine method, silver labelling of thiols was clearly achieved on the keratohyalin and cytofilament accumulations in the cells of the living epidermis and the plasma membrane of granular cells. to a certain extent, the envelope and cytoplasm of young corneocytes reacted equally i ... | 1991 | 1743999 |
[two novel reciprocal translocations involving chromosome 6 in the domestic pig]. | in the present study 2 new reciprocal translocations are described in two hypoprolific boars. the first one, a gascon/meishan boar, has produced a mean value of 7.37 +/- 0.69 piglets, vs 12.41 +/- 0.22 piglets per litter in contemporaries. the second one, a pietrain/large-white boar, has produced a mean of 5.42 +/- 0.69 vs 12.41 +/- 0.22 piglets per litter in contemporaries. each of these animals carries a new chromosome translocation involving chromosomes 6, 8 and 15, respectively. the first tr ... | 1991 | 1746885 |
effect of carcass size on rate of decomposition and arthropod succession patterns. | decomposition studies were conducted using two carcasses of domestic pigs, sus scrofa l., 8.4 kg and 15.1 kg in weight, to determine the effects of carcass size on the rate of decomposition, composition of the arthropod fauna, and succession patterns. a total of 46 arthropod taxa were recovered during this study. no size-related differences were observed between carcasses with respect to composition of the arthropod fauna or patterns of succession. a greater number of arthropods were observed at ... | 1991 | 1750396 |
natural history of 'deep dermal' burns in domestic pigs. | | 1991 | 1760120 |
prevalence of sarcocystis in domestic pigs in india. | muscle samples from 890 slaughtered pigs were examined for the presence of sarcocysts. a high prevalence rate of 67.98% was observed. two types of microsarcocysts were recorded. the sarcocyst wall of one type had redial striations and the other possessed hair-like villar protrusions. the species were identified as sarcocystis miescheriana and sarcocystis suihominis; there was a slightly higher incidence of the latter species (47.11%) than of the former (43.14%). s. suihominis has been identified ... | 1991 | 1763484 |
the porcine pgd gene is preferentially lost from chromosome 6 in pig x rodent somatic cell hybrids. | the 6-phosphogluconate dehydrogenase (pgd) and glucose phosphate isomerase (gpi) genes are both located on chromosome 6 in the pig (sus scrofa domestica). nonetheless, the pgd gene was absent in a total of 17 gpi-positive cell lines found in three independently derived panels of pig x rodent somatic cell hybrids. in most of these cell lines we found an apparently normal pig chromosome 6 at cytogenetic analysis. these results suggest instability of the porcine pgd gene region in interspecies hybr ... | 1991 | 1774184 |
glucose 6-phosphate dehydrogenase: isoenzymatic pattern in oesophagostomum venulosum, trichuris ovis and t. suis. | in the present communication we have studied the isoenzymatic pattern activity of the glucose 6-phosphate dehydrogenase (g6pd) in oesophagostomum venulosum, trichuris ovis and t. suis, parasites of capra hircus (goat), ovis aries (sheep) and sus scrofa domestica (pig) respectively, by polyacrylamide gel electrophoresis. different phenotypes have been observed in the g6pd isoenzymatic pattern activity in males and females of oesophagostomum venulosum. furthermore, g6pd activity has been assayed i ... | 1991 | 1795090 |
[the sensitive nerve endings of the clitoris of the sow (sus scrofa domesticus)]. | neural receptors of the porcine clitoris were examined using light and electron microscopy. perfusion with ink allowed study of the unique vascular arrangement associated with the genital corpuscles. sensory nerve-endings were generally rounded and formed a morphologically and structurally characteristic unit. they were composed of a network of primarily non-myelinated nerve fibers and flat cells. between these structures, isolated small blood vessels were embedded amongst collagen fibers and am ... | 1991 | 1796789 |
pharmacokinetic analysis of coronary sinus retroinfusion in pigs. ischemic myocardial concentrations in the left circumflex coronary arterial area using metoprolol as a tracer. | myocardial availability of drug, using metoprolol as a tracer, in acutely ischemic myocardium in the area of the left circumflex (lcx) coronary artery was compared following standard intravenous (iv) administration and after coronary sinus retroinfusion. seven open-chest farm pigs were subjected to a 21-minute occlusion of the lcx coronary artery. all animals received simultaneous iv tritium-labeled metoprolol (0.2 mg/kg) and unlabeled metoprolol (0.2 mg/kg) retrogradely into the coronary sinus. ... | 1991 | 1801888 |
anatomy and function of the cruciate ligaments of the domestic pig (sus scrofa domestica): a comparison with human cruciates. | pig cruciate ligaments were dissected and examined radiologically to evaluate their function. the variations in distance between the origin and insertion of the fibre bundles were measured in different joint positions; the maximal decrease in distance amounted to 50% in the anterior (acl) and 30% in the posterior cruciate ligament (pcl). the acl consists of 2 morphologically distinct portions. most of its fibres are found to be taut in extension. its posterolateral portion contains a 'guiding bu ... | 1991 | 1810918 |
normal anatomy of the aqueous humour outflow system in the domestic pig eye. | the normal functional anatomy of the aqueous humour outflow pathways in the domestic pig is poorly documented in the literature despite its being readily available and of a similar size to the human eye. anterior segment tissue from 12 pig eyes was appropriately fixed and investigated by light microscopy, and scanning and transmission electron microscopy. the configuration of the iridocorneal angle tissues is similar to other nonprimate mammals in several respects, i.e. it possesses a deep cilia ... | 1991 | 1810936 |
[the use of the measurement for the electrical resistance in order to standardize experimental cavities]. | for histological examination of the pulp responses to dental materials vital teeth are needed with an expected thickness of the cavity floor between 0.2 and 1.0 mm (din 13,930). in order to control the thickness of the cavity floor we used a method based on the measurement of the electrical resistance of the dentine layer, as previously described. the obtained results by evaluation the thickness of the floor of class v cavities, using the domestic pig as a model, indicate the accuracy of our met ... | 1991 | 1816831 |
ultrastructural identification of langerhans cells in normal swine epidermis. | langerhans cells of the epidermis of 6-month-old white crossbred farm pigs were identified by electron microscopy. ultrastructurally they were similar to those described in other mammals. they were present in basal and suprabasal layers and were characterised by a lobulated nucleus and an electrolucent cytoplasm with occasional dendritic processes, and the absence of tonofilaments and specialised unions with surrounding keratinocytes. they were specifically identified by the presence of characte ... | 1991 | 1817140 |
cardiovascular effects of platelet-activating factor. | sudden release of platelet-activating factor (paf) into the circulation can cause hypotension, tachycardia, and circulatory collapse. to further examine this response, we performed detailed studies of cardiovascular function after paf administration to young domestic pigs and newborn piglets. our results indicate that circulatory dysfunction after paf reflects severe constriction of pulmonary resistance vessels and consequent acute right ventricular failure. although paf-induced coronary artery ... | 1991 | 1819712 |
[the pig--an experimental model for transplantation of isolated islets pancreatic islets]. | the authors present results of autotransplantation of the islets of langerhans of the pancreas in pigs and miniature pigs ("troll"). diabetes was induced by total pancreatomy. from the removed pancreas the islets of langerhans were separated by the method of intraductal perfusion with collagenase and implanted into the spleen or liver via the portal vein. the mortality on operation in pigs was 33%, in miniature pigs 20%. in domestic pigs normal blood sugar levels were achieved in 25% after impla ... | 1991 | 1821478 |
asian taenia saginata: species or strain? | asian taenia has a special epidemiological pattern. many people eat raw and/or undercooked pork and pig viscera more often than that of cattle and acquire a t. saginata-like tapeworm infection. the pig has been found to be the most favorable laboratory intermediate host for four geographical strains of asian taenia. numerous pinpoint cysticerci have been found in naturally infected livers of one wild boar and six domestic pigs in taiwan. it is likely that pigs are the natural intermediate host o ... | 1991 | 1822898 |
evaluation of intraosseous vs intravenous antibiotic levels in a porcine model. | to compare intraosseous vs intravenous routes of administration and their effects on serum levels of four antibiotics in an animal model. | 1991 | 1858734 |
histochemical demonstration of zinc in the hippocampal region of the domestic pig: iii. the dentate area. | the distribution of zinc was described in the dentate area, a part of the hippocampal region, of the domestic pig. a modification of timm's sulphide silver procedure, the neo-timm method, was used for the histochemical demonstration of zinc. the staining of the dentate area exhibited a well-defined stratified pattern, the predominant part of the staining being restricted to the neuropil, although weakly stained nerve cell bodies were observed in the hilus fasciae dentatae. in the molecular layer ... | 1991 | 1865008 |
ciclopiroxolamine cream 1%: in vitro and in vivo penetration into the stratum corneum. | studies were conducted to assess the penetration of 1% ciclopiroxolamine cream, establishing the concentrations of the antimycotic compound in different layers of the stratum corneum with two skin models. results of in vitro studies using skin from domestic pigs indicate that ciclopiroxolamine has the ability to penetrate fast into the epidermis, by inhibiting and killing inoculated trichophyton mentagrophytes. in vivo investigation of the stratum corneum has been performed in healthy human volu ... | 1991 | 1878248 |
rapid and accurate high-performance liquid chromatographic method for the determination of 3-methylindole (skatole) in faeces of various species. | a rapid method for the determination of skatole (3-methylindole) in faeces by reversed-phase high-performance liquid chromatography is described. samples of 0.5 g were extracted with 2 ml of methanol. the extract was purified on amberlite xad-8. the lower limit of detection was 2.5 ng per injection (0.2 microgram/g faeces). the mean recovery of skatole was 95%, and the mean coefficients of variation were 7.0% (intra-assay) and 11.8% (inter-assay). skatole concentrations were clearly lower in fae ... | 1991 | 1885705 |
[high resolution chromosome g-banding pattern of domestic pig of china]. | lising methotrexate or thymidine treatment to induce synchronous division, combined with gtg technique, the high resolution banded chromosomes of seven domestic pig breeds of china were investigated. no distinct difference was found among then. hence, in line with the international system for human cytogenetic nomenclature, a standard idiogram of high resolution g-banded karyotype of domestic pig is suggested in this paper. in the idiogrammatic presentation of g-banding pattern, all the regions ... | 1991 | 1888527 |
immediate dressing of the burn wound--will it change its natural history? | thirty deep dermal burns were inflicted on six domestic pigs. on the treated animals, the epidermis was removed and immediately replaced with omiderm, xeroform or mettalin dressings. burns in which the blister was left intact or not dressed after epidermis removal, served as controls. macroscopic and microscopic assessment of the healing process was then carried out. surprisingly, the no-epidermis controls healed somewhat faster than did the untreated controls (those with blister intact). on day ... | 1991 | 1892559 |
comparison of 99mtc-teboroxime with thallium for myocardial imaging in the presence of a coronary artery stenosis. | this study tested the hypotheses in the setting of a coronary artery stenosis that 1) planar 99mtc-teboroxime myocardial scans are capable of providing a good estimate of relative coronary flow reserve, and 2) delayed washout of the tracer from the myocardium is a marker of reduced myocardial blood flow and, in certain cases, myocardial ischemia. | 1991 | 1914115 |
buffer solutions may compromise cardiac resuscitation by reducing coronary perfusion presssure. | --to investigate the effects of hypertonic buffer solutions on coronary perfusion pressure (cpp) and resuscitability during experimental closed-chest cardiac resuscitation. | 1991 | 1920701 |
plasma cocaine and tetracaine levels following application of topical anesthesia in a swine laceration model. | standard tac (0.5% tetracaine, 0.05% epinephrine, and 11.8% cocaine) solution is finding increased use as a topical anesthetic for lacerations. the extent of systemic absorption of tac components and their resultant physiologic effects are unclear. absorption of cocaine or tetracaine may result in serious toxicity. the investigators hypothesized that there are no measurable plasma cocaine or tetracaine levels after application of tac in a swine laceration model. after an overnight fast 10 domest ... | 1991 | 1930392 |