| further studies on the adjuvant effect of silica on ige antibody production in mice. | the effects of amorphous silica (aerosil) and of aluminium hydroxide on anti-dnp ige antibody production were studied in swiss mice preimmunized with ascaris protein and then challenged 7 days later with dnp-asc. aerosil exerted an adjuvant effect especially when it was injected together with the dnp-asc conjugate. al(oh)3 had a weaker adjuvant effect than that produced by aerosil and then only when it was injected with the dnp-asc conjugate. al(oh)3 given with ascaris extract 7 days before comp ... | 1979 | 221425 |
| experimental canine anaphylaxis: cyclic nucleotides, histamine, and lung function. | we studied the effects of ascaris suum antigen (iv) in 32 natively allergic, anesthetized dogs. after thoracotomy, bilateral cervical vagotomy, and propranolol, samples of peripheral lung frozen in situ were obtained for measurement of cyclic nucleotides and histamine. following ascaris, lung histamine decreased 20.4 +/- 3.7% (mean +/- se), camp increased 391 +/- 122%, and cgmp increased 110 +/- 20% with increased plasma histamine and physiological changes of anaphylaxis. no significant changes ... | 1979 | 224010 |
| hg2+-stimulated nadh-oxidase activity of ascaris muscle microsomal lipoamide dehydrogenase. | | 1979 | 230836 |
| carbon dioxide utilisation, and the regulation of respiratory metabolic pathways in parasitic helminths. | | 1975 | 237411 |
| the metabolism of foreign compounds in the cestode, moniezia expansa, and the nematode, ascaris lumbricoides var suum. | 1. the ability of the cestode moniezia expansa and the nematode ascaris lumbricoides var suum to metabolize foreign compounds has been assessed. 2. both species were unable to oxidase aldrin, aniline, biphenyl, butylbenzene and nitrobenzene or to demethylate aminopyrine, and 4-nitroanisole. 3. m. expansa and a. lumbricoides var suum readily induced 4-nitroanisole, nitrobenzene, 4-nitrobenzoic acid and 4-nitrophenol to the corresponding amines. azobenzene, dimethylaminoazobenzene, and 1,2-dimethy ... | 1975 | 239489 |
| 4-nitrobenzoic acid reductase of the nematode ascaris lumbricoides var suum. localization of the enzyme and optimum assay conditions. | 1. reduction of 4-nitrobenzoic acid by the nematode ascaris lumbricoides var suum occurred in the intestinal brush border cells. cuticle, mesenchyme fluid and reproductive tissue showed no activity. 2. 4-nitrobenzoic acid reductase was in the supernatant fraction after centrifugation of intestinal homogenates at 75 000 g for 2 h. 3. the enzyme required as cofactors nadh2, a low molecular weight thiol such as glutathione or cysteine and a divalent metal ion such as mn++ or cu++. the reduction wa ... | 1975 | 239490 |
| [simple method for obtaining toxocara canis antigen for the indirect immunofluorescence technic]. | a simple method for the preparation of toxocara canis antigen for the indirect immunofluorescent test is described: embryonated toxocara eggs are treated for 12 hours at room temperature with a 1:1 mixture of 2% naho and sodium hypochlorite (naclo) solution with a concentration of 2% free chlorine in order to remove the outer layers of the egg shells. the larvae which are still enclosed in the lipid membrane are freed by mild ultrasonic treatment. thereafter, the suspension of larvae is washed a ... | 1975 | 239550 |
| intestine of ascaris: oxygen consumption, fermentation acids, and anaerobic synthesis of protein. | the oxygen uptakes by pieces of gut from the porcine roundworm, ascaris suum, under po2 10 to 710 torr were from 0.6 to 3.0 mul/mg dry wt/hr (qo2). increasing concentrations of tissue, 30 to 90 mg (dry wt/3 ml) decreased qo2 in air from 1.9 to 1.1 and only technical grade catalase was found to relieve this inhibition. conversely aerobic fermentation, judged by acid production, was directly proportional to the amount of tissue present: the acids from this fermentation were 2-methyl-butyric (1% of ... | 1975 | 241780 |
| isocitrate lyase from parasitic and free-living nematodes. | | 1975 | 242262 |
| sequential immunologic stimuli to the respiratory tract: a paradox in the degree of potentiation of airway responses depending on the sequence of reverse passive and active immunologic stimulation. | immunologic stimuli to the airway of rhesus monkeys were given by aerosol challenge with ascaris antigen or anti-ige. both of these stimuli produce immediate-type airway responses. when 2 sequential aerosol challenges were given during the same experiment, the response following the second stimulus was always less than or equal to the first response following any combination of stimuli except the anti-ige-ascaris sequence. the second response following the latter challenge was always greater tha ... | 1977 | 262105 |
| [immunological diagnosis of filariosis in persons returning from tropical countries and in european and indigenous inhabitants of endemic areas (author's transl)]. | serum samples from persons who lived in areas where onchocerciasis occurred or who had filariasis were examined with the complement fixation test and the indirect hemagglutination test for the presence of antibodies against crude extracts from dirofilaria immitis, onchocerca volvulus, dipetalonema viteae, and ascaris suum. the results could be interpreted as follows: 1. the indirect hemagglutination test was more sensitive than the complement fixation test for the demonstration of antibodies in ... | 1977 | 271633 |
| ascaris egg in coprolite material. | | 1979 | 286922 |
| reaginic antibody production to ascaris suum allergen, asc-1. i. the function of glutaraldehyde-polymerized antigen in the induction of reaginic (ige) antibodies in the rat. | rats immunized with a purified ascaris suum allergen (asc-1) or with its dinitrophenylated derivate (dnp-asc-1) produced high levels of reaginic (ige) antibodies. a second injection of antigen given 30 days later did not result in an anamnestic ige antibody response. immunization of adult-thymectomized, lethally-irradiated and bone-marrow reconstituted (atxb) rats with soluble asc-1 or dnp-asc-1 failed to stimulate reaginic antibody production. the administration of glutaraldehyde-polymerized an ... | 1977 | 301862 |
| the immune response and acquired resistance to ascaris suum infection in mice with an x-linked b lymphocyte defect. | | 1977 | 303286 |
| socio-agricultural factors and parasitic infections in the caspian littoral region of iran. | surveys for intestinal parasites in villages in the babol area of the caspian littoral region of iran have been conducted for five years. during this period, mass chemotherapy and individual treatment have been administered. while the overall prevalence of parasitic disease was reduced after these campaigns, reinfection took place repeatedly, and at a rapid rate. this paper re-examines the prevalence of seven helminth species (ascaris lumbricoides), hookworms (ancylostoma duodenale and necator a ... | 1979 | 317393 |
| comparative studies on the evaluation of the effect of new anthelminthics on various intestinal helminthiasis in iran. effects of anthelminthics on intestinal helminthiasis. | the effect of pyrantel pamoate, levamisole, mebendazole, thiabendazole and bephenium hydroxynaphthoate on various intestinal helminths were evaluated among the inhabitants of four villages in the dezful area southwest of iran. a total number of 328 persons, all infected simultaneously with ascaris and hookworm (ancylostoma duodenale) and 49.2% with trichostrongylus spp., were randomly divided into six groups. one group was kept as the control and the other five were each treated with one compoun ... | 1977 | 318981 |
| anthelmintics. | this article describes the drugs used in helminthic infections and their therapeutic indications, mode of action, toxicity and other details of each of the recommended drugs, and discusses the nature and treatment of infection by helminths important in human medicine. infestation due to the roundworms enterobius vermicularis, ascaris lumbricoides and the hookworms, ancylostoma duodenale and necator americanus can all be treated effectively with pyrantel pamoate. for enterobius vermicularis, howe ... | 1977 | 319991 |
| ascaris suum: immune response in the guinea pig. i. lymphoid cell responses during primary infections. | | 1977 | 320026 |
| ascaris suum: lymphoid cell responses during secondary infections in the guinea pig. | | 1977 | 321239 |
| toxocara infection in pigs. the use of indirect fluorescent antibody tests and an in vitro larval precipitate test for detecting specific antibodies. | an in vitro larval precipitate test using second-stage toxocara canis larvae and an indirect fluorescent antibody (ifa) test employing cuticles of t. canis larvae as antigen were evaluated using antisera produced in pigs experimentally infected with t. canis, t. cati, ascaris suum, toxascaris leonina and parascaris equorum. the former test was both specific and sensitive and is suggested as a reliable and simple method of detecting toxocara antibodies in pigs. the latter test was considered unsu ... | 1977 | 328560 |
| ascaris suum: location of phosphorylcholine in lung larvae. | | 1977 | 330187 |
| intestinal and blood parasites in the north lore district, central sulawesi, indonesia. | over 1,000 stool specimens from residents of the napu and besoa valleys, central sulawesi, indonesia were examined. schistosoma japonicum was detected in 31% of napu valley residents while in only 2% of the besoa valley residents. hookworm infections were the most frequently encountered helminth parasitisms in both valleys. other helminth parasites encountered were: ascaris lumbricoides, trichuris trichiura, enterobius vermicularis, strongyloides stercoralis, physaloptera sp., diphyllobothrium s ... | 1977 | 335530 |
| an evaluation of levamisole for treatment of ascariasis. | levamisole (decaris, belgium) was tested in iran, brazil, and in mississippi and louisiana for its efficacy as a single-dose oral treatment for ascaris infections. subjects were children ages 2 to 15 years, and numbers treated with levamisole and comparative anthelmintics are as follows: 453 with levamisole; 461 with piperazine citrate; 17 with pyrantel pamoate; and 19 with a placebo. cure rates and total reduction in mean egg counts observed were 92% and 98% respectively for levamisole and 66% ... | 1978 | 341337 |
| toxocaral larva migrans: the use of larval secretory antigens in haemagglutination and soluble antigen fluorescent antibody tests. | toxocara larval excretions and secretions collected from in vitro culture were used as antigen in passive haemagglutination and soluble antigen fluorescent antibody tests for the diagnosis of visceral larva migrans in experimental animals and man. antibody to toxocaral secretions was detected in rabbits within 13 days of light toxocara infection (ten larvae per kg) and within four days of heavy infection (10(4) larvae). antibody was not detected following infection with 10(4) ascaris suum larvae ... | 1977 | 343311 |
| precipitating factors in respiratory allergic disease in indonesian children. | skin test results and ige antibody levels measured by rast indicate that hypersensitivity to house dust mite (d. pteronyssinus) is a major feature of asthma and allergic rhinitis in indonesian children. total serum ige levels were higher in the allergic than in control children. 60% (twenty-one out of thirty-five) of the asthmatic children and 56% (five out of nine) of the children with allergic rhinitis had ige antibodies to the helminth ascaris lumbricoides compared with none out of four contr ... | 1978 | 348344 |
| a comparative trial of oxantel-pyrantel and mebendazole in multiple helminth infection in school children. | in a pilot study in 17 children, oxantel-pyrantel as one single dose of 10 to 20mg/kg of each, gave good results in ascariasis but poor cure rates in both trichuriasis and necatoriasis. however in the latter groups the infection was extremely heavy. in a controlled trial in 51 children, using oxantel-pyrantel at the same dose, but given daily for 3 consecutive days, or mebendazole 100mg twice daily for 3 days, the drugs gave similar response rates. both gave 100% cure rates, as assessed by the a ... | 1978 | 350569 |
| immunodiagnosis of parasitic zoonoses: comparative efficacy of three immunofluorescence tests using antigens purified by affinity chromatography. | three immunofluorescent antibody assays were developed during this study: the direct (dfat) and indirect (ifat) fluorescent antibody tests using frozen worm sections, and the cyanogen bromide indirect fluorescent antibody test (cnbr-ifat) using helminth antigens purified by affinity chromatography bound on to commercially prepared cnbr-sepharose 4b beads. purified antigens used in the cnbr-ifat gave greater specificity and sensitivity than either the dfat or ifat. dirofilaria immitis, toxocara c ... | 1978 | 354114 |
| the biological suppression of malaria: an ecological and nutritional interrelationship of a host and two parasites. | the interrelationship of malaria and severe ascariasis was studied in anjouan children with a previously described syndrome of enlarged parotids, localized forehead edema, heavy infestation with ascaris lumbricoides, and unusual freedom from malaria. after treatment of 37 such children with the ascaricide piperazine, 35 had resolution of parotid enlargement and forehead edema, but 19 developed attacks of malaria. children treated with placebo had neither resolution of clinical findings nor attac ... | 1978 | 354372 |
| ascaris suum: specific antibodies in isolated intestinal loop washings from immunized swine. | | 1978 | 354957 |
| human parasitoses of the malili area, south sulawesi (celebes) province, indonesia. | a biomedical survey was conducted in 9 villages in the malili area of south sulawesi, indonesia. blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. malaria parasitemias were rare; plasmodium falciparum was detected in 10 and p. vivax in 11 of 985 blood smears. malayan filariasis was endemic to all villages surveyed. the overall prevalence of detectable microfilaremias was 15%, varying from 34% in kawata to 1% in nuha. microfilaria ... | 1978 | 364674 |
| prospects for the development of dead vaccines against helminths. | | 1978 | 364956 |
| the regulation of respiratory metabolism in parasitic helminths. | | 1978 | 364957 |
| [b-lymphocyte rosette formation phenomenon in the spleen of mice infested with ascaris suum larvae]. | | 1978 | 308152 |
| comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole. | in a double-blind study in cameroon the vermicidal effect of ciclobendazole, a new benzimidazole derivative, was evaluated and compared to mebendazole. ciclobendazole and mebendazole were equally effective in the treatment of ascaris and hookworm infestations. an increase in the dosis of ciclobendazole from 600 mg to 1200 mg did not lead to an improvement in the effectiveness. when treating trichuriasis significantly better results were achieved with mebendazole (p = 0.01). both drugs were toler ... | 1978 | 369076 |
| non-specific potentiation of ige by parasitic infections in man. | infection with the helminthic parasites ascaris lumbricoides and/or necator americanus (hookworm) induces the production in man of high levels of serum ige. the specificity of this ige antibody when measured by rast to a wide range of allergens was restricted in general to the helminthic antigens. absorption of the sera with immunosorbents produced by coupling extracts of a. lumbricoides to cnbr activated sepharose 4b established that ascaris antigen specific ige antibodies contributed a minor f ... | 1979 | 370030 |
| evaluation of a new antihelminthic for trichuriasis, hookworm, and stronglyloidiasis. | mebendazole was tested in a double-blind trial for its efficacy in the treatment and control of enteric helminths. one hundred and twenty-two children from a community near the gulf of carpentaria, and from a community in cape york peninsula in northern queensland were divided into two equal groups to receive a course of either mebendazole or placebo after the identification of one or more intestinal helminths in a single pretreatment specimen of faeces. between the tenth and twentieth days afte ... | 1979 | 381876 |
| the role of mucociliary dysfunction in bronchial asthma. | abnormalities of mucociliary function in the airways of patients with bronchial asthma are suggested by the clinical observation of excessive tracheobronchial secretions which are difficult to expectorate and may contribute to bronchial obstruction. pathologic and functional studies in animals and patients have demonstrated an impairment of mucociliary transport mechanisms, but the pathogenesis of this abnormality is still poorly understood. in patients with allergic asthma, the elaboration of c ... | 1979 | 382847 |
| ascaris and growth rates: a randomized trial of treatment. | three hundred forty-one tanzanian preschool children were randomly assigned to levamisole or placebo treatment given at three-month intervals. weights and heights were measured at the tri-monthly treatment visits for a period of one year. among the 273 children who were seen and weighed at the one-year follow-up visit, the rate of weight gain was 8 per cent greater for those receiving levamisole than for placebo-treated controls (p = .06). in 78 children known to be infected with ascaris at base ... | 1979 | 384815 |
| regulation of antibody response in different immunoglobulin classes. ii. induction of in vitro ige antibody response in murine spleen cells and demonstration of a possible involvement of distinct t-helper cells in ige and igg antibody responses. | in vitro induction of anti-dnp ige as well as igg1, igg2a antibody responses was shown in murine spleen cell culture. spleen cells primed three times with 1 mug of dnp-oa or dnp-asc produced significant amounts of anti-dnp ige as well as igg antibodies by the in vitro stimulation with dnp-oa or dnp-asc, respectively. collaboration between dnp-primed b cells and carrier-primed t cells was required for the induction of both ige and igg antibodies with dnp-coupled t-dependent antigen. carrier-speci ... | 1977 | 300389 |
| prevalence of intestinal parasitic infections among inhabitants of tan-nan village, nantou county, taiwan. | the pork infected with cysticerci was sent to our laboratory in june 1971. microscopic examination revealed the infection of cysticercus cellulosae. subsequently, the source of the pork was traced, and the survey of intestinal parasitism was carried out among inhabitants at tan-nan village, hsin-i district, nantou county, taiwan, in august 1973. results obtained only indicated the presence rather than endemic of taeniasis solium in this village. the parasites and infection rates found in the pre ... | 1979 | 397878 |
| ascaris suum: cuticular binding of the third component of complement by early larval stages. | | 1977 | 403088 |
| structure and physiological activity of the motoneurons of the nematode ascaris. | the nervous system of the nematode worm ascaris contains about 250 nerve cells; of these, the motoneurons consist of five segmental sets, each containing 11 cells. morphologically, the motoneurons can be divided into seven different types. their geometry is simple: some are unbranched, others have one branch point, and the most complex have two. there is no neuropil in the nerve cords; synapses are made by axo-axonal contact or onto short spines. these features enable us to study the anatomy and ... | 1978 | 277952 |
| a comparative study of the anti-allergic effects of disodium baicalein 6-phosphate (bps) and disodium cromoglycate (dscg). | a comparative study was carried out on the effects of a soluble derivative of baicalein, disodium baicalein 6-phosphate (bps) and disodium cromoglycate (dscg) on the immediate type allergic reactions. bps not only inhibited reaginic antibody-mediated reactions including antigen-induced mediator release from monkey lung, homologous pca in rats, and reaginic antibody-mediated degranulation of mast cell, but also non-reaginic antibody-mediated reactions such as mediator release from guinea pig lung ... | 1977 | 405519 |
| airway mucosal permeability in the ascaris suum-sensitive rhesus monkey. | the permeability of the airways to technetium 99m-labeled albumin was measured in ascaris suum-sensitive rhesus monkeys. all 8 animals were skin-sensitive to ascaris suum (aa) antigen, 4 being respiratory responders (r) and 4 nonresponders (nr) to aerosolized antigen. in the absence of antigen challenge there were no differences in the accumulation in the blood of radioactive material from the tracheobranchial tree between the r and nr animals. after a five-minute challenge with aerosolized aa, ... | 1977 | 406301 |
| effect of pge1 on immediate-type immunologic and pharmacologic respiratory responses of the rhesus monkey. | the effect of prostaglandin (pg)e1 on the acute, immediate-type airway response to antigen, carbocholine, pgf2alpha, histamine, and physostigmine was studied. in contrast to isoproterenol, which affects all abnormalities of pulmonary function, pge1 selectively reversed only abnormalities of pulmonary resistance and dynamic compliance. prior exposure to pge1 minimally inhibited airway responses but when given simultaneously with antigen, it either selectively inhibited some or dampened all pulmon ... | 1977 | 406337 |
| allergy induced asthma with ascaris suum administration to dogs. | | 1977 | 407388 |
| the difference in effect of predosing with antiallergic compounds between the rat pca model and the monkey asthma model. comparison of the effects of prd-92-ea and disodium cromoglycate. | dscg and prd-92-ea showed tachyphylaxis in the rat pca test when a large intravenous dose (40 mg/kg of dscg and 20 mg/kg of prd-92-ea) was given 30 min before administering intravenously the expected effective doses at the time of antigen challenge. this predosing led to a marked loss of effectiveness. cross-reacting tachyphylaxis was also demonstrated in this model. predosing rats with dscg led to a great loss of effectiveness of a subsequent expected active dose of prd-92-ea and predosing with ... | 1977 | 412794 |
| [endoparasites of calves in large herds]. | the authors present preliminary results of the coprological examination of calves in large-capacity calf-houses. in a new large-capacity calf-house in the benesov district in the central-bohemian region, 200 samples of faeces were examined according to breza (1957) and further examinations were performed regularly in a group of 42 calves from the age of 0.5 to 6 months. the tests revealed 13 species of endoparasites, including eight species of coccidia: eimeria auburnensis, e. alabamensis. e. bo ... | 1977 | 413242 |
| dopaminergic neurons in the nematode caenorhabditis elegans. | dopamine is the putative transmitter of eight neurons in the hermaphrodite form of the nematode caenorhabditis elegans. these include the cephalic and deirid neurons, which are believed to be mechanosensory. the male has an additional six dopaminergic neurons in the tail. mutants have been selected which have defects in the formaldehyde induced fluorescence and lack dopamine to varying degrees, but they are not insensitive to touch. the dopaminergic neurons of c. elegans are compared with the ho ... | 1975 | 240872 |
| the qualitative evaluation of airway responses to immunologic and pharmacologic stimuli in rhesus monkeys. | this report describes the current status of a colony of rhesus monkeys composed of a group of animals with consistent asthmatic responses to ascaris antigen challenge, a variable group and a negative group. the cumulative experience with the consistent group of 5 animals totals 144 months of observation with 86 positive respiratory responses to 86 aerosol challenges. further studies compare rhesus airway responses to ascaris antigen, anti-ige, histamine, prostaglandin (pg)f2alpha, carbocholine, ... | 1978 | 416064 |
| a comparative trial of the anthelminthic efficacy of pyrantel pamoate (combantrin) and thiabendazole (mintezol). | the anthelminthic efficacy of pyrantel pamoate (combantrin) in a single dose of 10 mg/kg body weight was compared with that of thiabendazole (mintezol) in two doses each of 25 mg/kg body weight in a controlled trial. follow-up examination, 6 weeks after treatment with combantrin gave cure rates of 93.8%, and 29.1% for infection with ascaris and the hookworm respectively, and 44.3% and 27.3% in those treated with mintezol. the reduction in hookworm egg counts was higher in patients treated with c ... | 1977 | 416671 |
| the effect of arachidonic acid on airway responses of rhesus monkeys. | | 1978 | 417227 |
| [ovocidal parameters of ultrasound for the eggs of swine nematodes]. | | 1979 | 419670 |
| malabsorption of water miscible vitamin a in children with giardiasis and ascariasis. | vitamin a absorption was studied using a water-miscible oral preparation of vitamin a in 19 children ages 1 1/2 to 9 years old with giardiasis and/or ascariasis, both before and after their eradication with appropriate therapy, and in three children without parasites. marked impairment of vitamin a absorption was noted when administered in a water miscible form in children with 1) combined infection with giardia lamblia and ascaris lumbricoides, 2) giardiasis alone, and 3) in a proportion of chi ... | 1979 | 420128 |
| ascaris lumbricoides and perforation of the ileum: a critical review. | ileal perforation due to typhoid bacilli is the commonest cause of peritonitis in the tropics. perforation due to ascaris lumbricoides is rare. three cases of ileal perforation believed to be due to a. lumbricoides are presented and the evidence critically reviewed. it is suggested that signs of heavy infestation with a. lumbricoides make a diagnosis of intestinal perforation more likely in a patient with an acute abdomen. | 1979 | 420985 |
| purification and properties of the ascaris pyruvate dehydrogenase complex. | the pyruvate dehyhdrogenase complex (pyruvate:lipoate oxidoreductase (decarboxylating and acceptor-acetylating), ec 1.2.4.1) has been isolated from ascaris muscle mitochondria and purified to near homogeneity by differential centrifugation, (nh4)2so4 fractionation and calcium phosphate gel-cellulose chromatography. it is similar in shape, size and physical characteristics to pyruvate dehydrogenase complexes isolated from mammalian sources. it has an absolute dependence on coa, nad+ and pyruvate ... | 1979 | 227453 |
| [distributions of ascaris lumbricoides, necator americanus and trichuris trichiura in 6 villages of ivory coast (author's transl)]. | results of stool controls (kato's technic) in 425 children from 7 to 14 years old in 6 villages of the south districts of ivory coast. necator and trichuris have a high prevalence (75 p. 100) versus 40 p. 100 for ascaris-trichuris is specially frequent in urban and suburban areas. | 1979 | 225636 |
| non-infantile intussusception. | in europe and north america, most cases of non-infantile intussusception are associated with intestinal neoplasm. at the university college hospital, ibadan, nigeria, the majority of cases of intussusception seen are ileocecocolic and cecocolic types. these are usually not associated with intestinal neoplasm and simple reduction is all that is required.intussusception occurring in other segments of the intestinal tract is found to be associated with intestinal neoplasm, mesenteric lymphadenopath ... | 1979 | 423279 |
| comparative studies on actins from various sources. fragments of actins from ascaris muscle cleaved at cysteinyl residues in comparison with those of other actins. | pure actins were obtained from various animal muscles: vertebrata (skeletal, smooth, and cardiac muscles), prochordata (smooth muscle), nematoda (obliquely striated muscle), and mollusca (striated, smooth and obliquely striated muscles). these actins were all identical in apparent molecular weight on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. all actins treated with 2-nitro-5-thiocyanobenzoic acid yielded four major (about 33,000, 26,000, 24,000, and less than 10,000 daltons) and ... | 1979 | 429256 |
| [ecological prerequisites for the spread of ascariasis in the mountainous zone of the yemen arab republic]. | | 1979 | 431501 |
| the role of upper airways and of sensoric receptors on reflex bronchoconstriction. | the influence of bilateral transection of the nervi laryngici cranialis, laryngici caudalis and glossopharyngici on ach and allergen-induced bronchoconstriction was tested in 15 dogs. in three dogs the free preparation of bilateral nervi laryngici cranialis was performed for control measurements. partial transection of pulmonary left nervus vagus was performed in three dogs and compared to radical transection of the same nerve in three animals. transection of the nervi laryngici cranialis as wel ... | 1979 | 432444 |
| ascaris suum: suppression of reaginic and hemagglutinating antibody responses in the mouse by crude extract and maintenance fluid. | | 1979 | 437015 |
| kinetic and isotope partitioning studies on the nad+-malic enzyme from ascaris suum. | | 1978 | 204633 |
| therapeutical influence of vagus blockade on antigen-induced airway obstruction. | the influence of bilateral vagus blockade on airway resistance induced by allergen exposure, while aerosol was given, was tested on 3 dogs. the therapeutic effect of vagus blockade could be demonstrated, which showed to be in a same degree as its prophylactic effect demonstrated in experiences before. | 1979 | 441527 |
| the role of upper airways in antigen-induced bronchoconstriction. | the bronchoconstrictor effect of antigen was tested in 15 dogs. the upper and the lower airways were sequently exposed through a specially confected endotracheal tube. the antigen was also generally administered through a mouth mask. bronchoconstriction was induced after each kind of exposure. the results argue for reflex bronchoconstriction. the sensory receptors localized in the upper part of the airways are responsible for about 50% of antigen-induced bronchoconstriction. the decrease of po2a ... | 1979 | 441542 |
| porcine respiratory disease in the western cape province. | the aetiology and pathogenesis of respiratory syndromes in pigs are reviewed with emphasis on the role of environmental factors and diagnosis. therapeutic and control measures are suggested and the cost of various regimens is dealt with in detail. | 1977 | 195053 |
| relationship between serum ige levels and intestinal parasite load in african populations. | serum ige determinations and coproparasitological analyses were carried out on 161 individuals from two distinct ethnic groups (hutus and twas) from two regions in rwanda (north and south). the cumulative parasitosis index (calculated for each individual as the sum of the scores for the four most frequent intestinal parasites) show a linear relation with ige levels up to a plateau, with no clear pattern of correlation between the score for any given parasite and the ige level. such a direct quan ... | 1979 | 447419 |
| regulation of ige antibody production by serum molecules. iv. complete freund's adjuvant induces both enhancing and suppressive activities detectable in the serum of low and high responder mice. | two biologically active serum molecules manifesting precisely opposite biologic effects, both of which are selective for ige antibody synthesis, can be detected in the serum and ascites fluids of cfa-immune mice. one activity, described previously, is suppressive and hence termed suppressive factor of allergy (sfa); the other, reported for the first time herein, is enhancing and has been termed enhancing factor of allergy (efa). the ability to detect one vs the other activity requires certain sp ... | 1979 | 448123 |
| elevated levels of ige antibodies to ascaris and mite antigens in papua new guinea. | levels of ige as well as specific ige antibodies to ascaris and mite have been studied in two groups in papua new guinea (png), patients with primary liver carcinoma (plc) and normal blood donors, and in two groups in japan, normal subjects and asthmatic patients. a radioallergosorbent test was used to measure ige antibodies to ascaris and mite antigens. much higher levels of ige were found in the papua new guinean subjects than the normal japanese subjects. also levels of ige antibodies to asca ... | 1976 | 180315 |
| the effect of histamine on lymphocytes : release of an inhibitor of eosinophil chemotactic migration. | | 1979 | 463658 |
| dose titration of oxfendazole against common nematodes of swine. | oxfendazole, a benzimidazole carbamate, was administered as a 0.5% feed additive to 88 pigs naturally infected with two to four nematode species. dose rates of 1.5 mg/kg of body weight, 3.0 mg/kg, 3.75 mg/kg, 4.5 mg/kg, 6.75 mg/kg, or 9.0 mg/kg were 100% efficacious against oesophagostomum dentatum and 99.2% to 100% effective against ascaris suum. dose rates of 4.5 mg/kg, 6.75 mg/kg, and 9.0 mg/kg were 92.7%, 98.9%, and 99.5% effective, respectively, against mixed populations of metastrongylus a ... | 1979 | 464370 |
| the effects of stibophen on phosphofructokinases and aldolases of adult filariids. | trivalent organic antimonials, such as stibophen, have been employed for the chemotherapy of schistosome and filariid infections. the effects of stibophen on adult litomosoides carinii, dipetalonema witei (= viteae), and brugia pahangi were examined. in vitro, lactate accumulation was markedly inhibited by the antimonials as was phosphofructokinase activities in homogenates. incubation of filariids with stibophen and determination of internal concentrations of hexose phosphate also indicated a d ... | 1975 | 171364 |
| esophagogastric ulcers in swine infected with ascaris suum. | | 1979 | 473495 |
| toxocara and ascaris infection in british pigs: a serological survey. | a serological survey of growing pigs from farms throughout great britain revealed that antibodies to toxocara and ascaris larval antigens were present in 4.5 per cent and 39.3 per cent respectively. heavy infection with toxocara occurred only rarely and it is considered that this parasite is unlikely to be an important cause of chronic focal interstitial hepatitis. antibodies to both nematodes were detected more frequently in heavy hogs than in pigs of lighter weight. reginal differences in the ... | 1979 | 473574 |
| bronchial asthma in nigerian children. | clinical and laboratory studies on bronchial asthma in 200 nigerian children who were seen during a 2 1/2-year period in ibadan are described. contrary to reports that the condition is rare in african children, after pulmonary tuberculosis, asthma is the next most common chronic chest disease in ibadan. while many features of the disease are similar to those seen elsewhere, skin tests indicate that ascaris is the most common antigen associated with asthma, followed by dermatophagoides pteronyssi ... | 1979 | 475428 |
| mass control of ascariasis with single oral doses of levamisole. a controlled comparison in 3,056 subjects between three incomplete population coverages. | ninety-, 60-, and 40-percent population coverages with levamisole 2.5 mg/kg of body weight were compared for their effects on ascaris lumbricoides, ancylostoma, strongyloides stercoralis, and trichuris trichiura infections. they were shown to be effective in maintaining a reduced prevalence of a. lumbricoides in the treated subjects for 9, 6, and 3 months, respectively. nine months after treatment, the prevalence of ascariasis was still lower than before treatment both in the levamisole and in t ... | 1979 | 483364 |
| [interrelationship of sanitary-helminthological and epidemiological indices in microfoci of ascaridiasis]. | | 1976 | 137169 |
| the isolation and partial characterization of a protective antigen from developing larvae of ascaris suum. | | 1979 | 489237 |
| the location of sensoric bronchoconstricting receptors in the upper airways. | the bronchoconstrictoric influence of allergen and acetylcholine aerosol was tested in 16 boxer dogs. the animals were exposed to these substances through a mask. the aerosol was also administered directly to three restricted areas of the trachea. both substances induced a strong bronchoconstriction when administered through the mouth. only the allergen showed a similar strong bronchoconstriction when administered to a restricted area in the upper third of the trachea. | 1979 | 493725 |
| [experimental studies on anthelmintics (xxvi). biochemical and pharmacological studies of 4-iodothymol on ascaris lumbricoides suum]. | we have shown previously that 4-iodothymol (it) produces a contraction in ascaris muscle, probably due to the myogenic action. in this paper, the effects of it on the carbohydrate metabolism in ascaris muscle have been investigated in comparison with those of hexylresorcinol (hex), santonin (s) and piperazine (pip). (1) hex (200 approximately 400 mug/ml) showed a strong nonspecific inhibition on the formation of succinate from fumarate in muscle homogenate, the phosphofructokinase (pfk) activity ... | 1976 | 136389 |
| ketamine block of bronchospasm in experimental canine asthma. | experimental asthma was induced in dogs previously sensitized to ascaris antigen by ventilation with ascaris antigen, in an aerosol, for 10 min. before the administration of antigen, there was no significant difference in pulmonary airways resistance (rl) during thiopentone and ketamine anaesthesia. in dogs anaesthetized with thiopentone, rl increased significantly from a pre-antigen control of 0.36 +/- 0.13 (mean +/- sem) kpa litre-1 s to 1.56 +/- 0.38 at 5 min after administration of antigen. ... | 1979 | 497067 |
| effect of ascaris suum and other adjuvants on the potentiation of the ige response in guinea-pigs. | the potentiation effect of various adjuvants on the production of guinea-pig ige was investigated using freund's complete and incomplete adjuvant, the lipopolysaccharide of escherichia coli and salmonella typhosa, bordetella pertussis, and the nematodes nippostrongylus brasiliensis and ascaris suum. while all the antigens had a variable effect on the potential of the igg response, only infection with a. suum resulted in an enhanced ige response to the antigen, egg albumin. maximum potentiation o ... | 1979 | 500118 |
| a new biologic activity of histamine: release of a chemotaxis inhibitor from lymphocytes. | | 1979 | 503068 |
| purification of lipoamide dehydrogenase from ascaris muscle mitochondria and its relationship to nadh:nad+ transhydrogenase activity. | | 1979 | 507807 |
| satellite dna properties of the germ line limited dna and the organization of the somatic genomes in the nematodes ascaris suum and parascaris equorum. | during the early cleavage divisions in some ascarids, parts of the chromosomes are eliminated from the somatic blastomeres ("chromatin diminution", boveri, 1887) while the chromosomes in the germ line cells maintain their integrity. to characterize the germ line and soma genome, dna was isolated from gametes and embryonic somatic cells of two ascarid species, parascaris equorum var. univalens and ascaris suum. it was shown that the germ line limited dnas of these species have the same density an ... | 1979 | 510087 |
| ascaris sp.: water loss during desiccation of embryonating eggs. | | 1979 | 510444 |
| immunopathology of toxocara canis and ascaris suum infections of the eye: the role of the eosinophil. | intravitreal infection of guinea pigs with second-stage larvae of toxocara canis and second- and fourth-stage larvae of ascaris suum induced intraocular ige antibodies and a dense eosinophil infiltration in the anterior chamber and throughout the uveal tract. the eosinophil infiltrate began within 1 day after infection and persisted for as long as 51 days. by day 12 after intravitreal infection, the injected ascarid larvae were surrounded by granulomas which consisted almost entirely of eosinoph ... | 1979 | 511459 |
| antigen-induced bronchospasm in conscious sheep. | in 10 conscious ewes with cutaneous sensitivity to ascaris suum, measurements of pulmonary resistance (rl), static lung compliance (cst), functional residual capacity (frc), and arterial blood gas composition along with arterial plasma histamine concentration (h) were obtained before and after inhalation challenge with a. suum extract. five animals showed no changes in respiratory mechanics after a. suum challenge; in these h did not change. the remaining five animals responded to a. suum challe ... | 1979 | 511716 |
| dependence of the guinea pig ige and igg1 immune responses on the inclusion of potassium in the preparation of alum adjuvant. | primary immunization with alum prepared using alk(so4)2 and adjuvant enhanced ige production in the guinea pig. alum prepared from al2 (so4)3 showed greatly reduced ige and igg1 anti-ea titers. this variance in immunoglobulin titer was observed only in the guinea pig. both rats and mice respond to alum preparations prepared from either alk(so4)2 or al2(so4)3 equally as well. | 1979 | 512373 |
| [effectiveness of soil helminthological study methods]. | | 1979 | 514215 |
| the metabolism of nitrophenolic and 5-arylazorhodanine anthelmintics by ascaris suum, moniezia expansa and by mouse- and sheep-liver enzymes. | 1. the anthelmintics disophenol (2,6-diiodo-4-nitrophenol), nitroxynil (3-iodo-4-hydroxy-5-nitrobenzonitrile) and nitrodan (3-methyl-5-(4-nitrophenylazo)rhodanine) were reduced in vitro to the corresponding amines by intact ascaris suum, moniezia expansa, by enzymes prepared from these helminths, and by mouse- and sheep-liver homogenates. helminth reductases required nadh2 and glutathione as cofactors and were inhibited about 50% by 2.0 x 10(-7) m allopurinol. azo bonds of nitrodan and its analo ... | 1979 | 516789 |
| the effects of ammonium, inorganic phosphate and potassium ions on the activity of phosphofructokinases from muscle and nervous tissues of vertebrates and invertebrates. | 1. the effect of nh4+, pi and k+ on phosphofructokinase from muscle and nervous tissues of a large number of animals was investigated. the activation of the enzyme from lobster abdominal muscle by nh4+ was increased synergistically by the presence of pi or so4(2-). in the absence of k+, nh4+ plus pi markedly activated phosphofructokinase from all tissues studied. in the presence of 100 mm-k+, nh4+ plus pi activated phosphofructokinase from nervous tissue and muscle of invertebrates and the enzym ... | 1975 | 128356 |
| proteolytic enzymes and enzyme inhibitors in ascaris suum. iv. estimation of molecular weights of chymotrypsin inhibitors and an intestinal protease by gel chromatography. | | 1979 | 517354 |
| proteolytic enzymes and enzyme inhibitors in ascaris suum. v. influence of parasite gut content on host amylase and lipase. | | 1979 | 517355 |
| studies on the subunits of myosin from muscle layer of ascaris lumbricoides suum. | 1. a purified preparation of ascaris myosin was obtained from the muscle layer of ascaris lumbricoides suum, using gel filtration and ion-exchange chromatography. 2. ascaris myosin whether purified or unpurified, had almost the same ability for atp-splitting and superprecipitation. 3. ascaris myosin and rabbit skeletal myosin were subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis. a significant difference in the number of light chains between both myosins was found. ascaris ... | 1975 | 127618 |
| serologic differentiation of larval toxocara and ascaris. | antigenic extracts of adult and larval t. canis and a. suum have been used in microgel double diffusion technique to differentiate antibodies produced in animals, experimentally infected with these parasites. antigenic extracts from adult ascaris reacted with the sera from animals infected with a. suum but the extracts from adult toxocara failed to react or reacted feebly with the sera from animals infected with t. canis. interestingly the antigenic extract from adult toxocara reacted with the s ... | 1979 | 121696 |
| ige and igg1 antibody production by a soluble product of ascaris suum in the guinea-pig. | third-stage larvae of ascaris suum cultured to the fourth stage in a chemically defined culture medium produced a substance, the 'acf antigen', which was allergenic in the guinea-pig. when three different concentrations (3.1, 31 and 62 micrograms) of the acf antigen were given intraperitoneally, only the highest concentration induced a primary ige specific antibody response (1:100 titre) as determined with the passive cutaneous anaphylaxis reaction. upon secondary exposure all concentrations dem ... | 1979 | 521052 |
| the influence of environmental temperature on the rate of development of ascaris suum eggs in great britain. | the rate of development of ascaris suum eggs was recorded during 18 months in england. every second or third week unembryonated eggs were placed in an unheated animal house and their development was observed at weekly intervals. eggs underwent no development during november to may. embryonation was most rapid during june, july and august. the shortest time for eggs to reach the infective stage was two weeks in 1976 and four weeks in 1977. a relationship was apparent between the rate of developme ... | 1979 | 523803 |
| [kininogenic activity of rabbit plasma in experimental poisoning with coelomic fluid of ascaris lumbricoides suis]. | | 1979 | 524888 |
| some properties of the sulphoxidases and sulphoxide reductases of the cestode moniezia expansa, the nematode ascaris suum and mouse liver. | 1. the anthelmintics bithionol, phenothiazine, albendazole and fenbendazole were oxidized to sulphoxides by enzymes in the cytosol of the proglottids of the cestode moniezia expansa and the cytosol of the intestinal epithelial cells of the nematode ascaris suum. enzymes in these tissues were also able to reduce these sulphoxides to the thioethers in the absence of oxygen. 2. sulphoxidation and sulphoxide reduction also occurred in mouse liver enzyme preparations. about 20% of the sulphoxidation ... | 1979 | 532217 |