| studies of sperm antigenicity. 6. in vivo and in vitro cellular reactivity in guinea pigs sensitized with fractions of guinea pig spermatozoa. | normal guinea pig spermatozoa cells were homogenized by a french pressure cell. three soluble and three insoluble fractions were obtained by ultrascentrifugation and (emulsified in cfa) were used for guinea pig sensitization. the following were observed: 1) all fractions were immunogenic except one; 2) in vivo and in vitro delayed hypersensitivity was elicited in animals immunized with these fractions; 3) two distinctive histopathologic lesions were observed in the testes of sensitized animals: ... | 1977 | 69611 |
| the use of immunoabsorbents for the purification of mycobacterial antigens. | affinity chromatography using immunoabsorbents prepared from goat antisera has been applied to the purificaton of antigens from culture filtrates of mycobacterium tuberculosis. the optimum conditions for the preparation and use of these immunoabsorbents have been determined. urea has been studied as an eluant, and it has been found that antigen can be eluted with 4m urea at ph 9 with satisfactory yields, minimal loss of antigenicity, and minimal disruption of the immunoabsorbent. | 1977 | 69672 |
| [cross-resistance of tubercle bacilli (a review) (iii) (author's transl)]. | | 1977 | 69737 |
| increased intracellular growth activity of tubercle bacilli excreted during treatment. | | 1977 | 70627 |
| [isolation of live and dead mycobacteria tuberculosis by the method of differential cytochemical staining]. | | 1977 | 72885 |
| [evaluation of different methods of urine processing for detection of mycobacterium tuberculosis. 2]. | | 1977 | 72886 |
| the chromophobic tubercle bacilli and the problem of endogenous reactivation of tuberculosis. | | 1977 | 72893 |
| minimum structural requirements for encephalitogen and for adjuvant in the induction of experimental allergic encephalomyelitis. | | 1978 | 74289 |
| adjuvant and immunostimulating activities (in the absence of freund's incomplete adjuvant) of chemically modified low molecular weight mycobacterial peptidoglycans. | relatively low molecular weight peptidoglycan fragments extracted from two strains of mycobacterium tuberculosis var. hominis were chemically coupled with lauric acid. the fatty acid conjugates were compared with the native substances with respect to some immunopotentiating activities. in vitro, the mitogenic effect on murine spleen lymphocytes was significantly enhanced following conjugation. one of the lauric acid conjugates stimulated, upon intravenous administration in mice, the formation of ... | 1978 | 75834 |
| high dose inhibition of the tryptophan peptide induced encephalitogenicity. | in a previous publication (immunol. comm. 3:219, 1974) a hypothesis was proposed that the high dose inhibition of encephalitogenicity in giunea pigs seen with the tryptophan peptide, phe ser trp gly ala glu gly gln arg, and not observed with the whole myelin basic protein which contains this sequence, was the result of competitive inhibition by non-encephalitogenic fragments of the tryptophan peptide produced in vivo possibly by exopeptidases. i present data which disagrees with this hypothesis. | 1978 | 75835 |
| granuloma formation by synthetic bacterial cell wall fragment: muramyl dipeptide. | a synthetic muramyl dipeptide, n-acetylmuramyl-l-alanyl-d-isoglutamine, which possesses the same structure as that of a part of the peptidoglycan monomer of wax d of tubercle bacilli or bacterial cell walls was found to induce, when injected in water-in-oil emulsion, massive granulomas often accompanying abscesses in the site of injection and draining lymph nodes of guinea pigs and rats. the granulomas were composed mainly of epithelioid cells 2 weeks after injection and were indistinguishable f ... | 1978 | 75847 |
| [improvement of the method of handling of the sputum and bronchial irrigation fluid for detection of mycobacterium tuberculosis]. | | 1978 | 76709 |
| [protection against infection with bordetella pertussis by an oligopeptide from bordetella pertussis (author's transl)]. | we have isolated from bordetella pertussis an oligopeptide with characteristic amino acid composition. this peptide was applied to mice in standardized tests for pertussis immunization. in three tests with three independent isolates of peptide, a significant and dose dependent protection was observed. one microgram of peptide per mouse produces the same protective effect as 0.1 iu of pertussis vaccine. it is important to note that similar peptides can be isolated from other bacteria and other dn ... | 1978 | 77606 |
| some observations of mycobacterial acid-fastness. | mycobacterial acid-fastness seems most readily explainable on the basis of a "lipids barrier principle" that in the first instance hinders penetration of the water-soluble dyestuff, and in the second, hinders penetration of the bleaching acid. mycolic acids, and more especially, mycolate salts, in xylene solution complex and solubilize crystal violet, but the complex is demonstrably not stable even to weak acids. stained mycobacterial preparations are readily bleached by an acidified lipid solve ... | 1978 | 79318 |
| [fluorescence microscopy in the diagnosis of tuberculosis (review of the literature)]. | | 1978 | 79675 |
| [quantitative variant of the complement fixation test for detection of antimicrobial and anti-tissue antibodies]. | | 1978 | 79684 |
| controlled clinical trial of five short-course (4-month) chemotherapy regimens in pulmonary tuberculosis. first report of 4th study. east african and british medical research councils. | five 4-mo regimens of chemotherapy for tuberculosis are compared. the two regimens in which rifampicin was given throughout the 4 mo were associated with bacteriological-relapse rates of 8% in the first 6 mo after stopping chemotherapy, but the three regimens in which rifampicin was given for only the first 2 mo had relapse-rates of 24-32%. there was no evidence that the addition of pyrazinamide in the second 2 mo of chemotherapy reduced the bacteriological-relapse rate. removal of the streptomy ... | 1978 | 79708 |
| pulmonary tuberculosis and bronchial carcinoma. | | 1978 | 79734 |
| the correlation of bacteriophage types of mycobacterium tuberculosis with guinea-pig virulence and in vitro-indicators of virulence. | among 58 isoniazid-sensitive strains of mycobacterium tuberculosis from india, burma and east africa, 23 were of phage type a, 31 of type i (intermediate), 4 of type b and none of type c. type i strains differed from type a strains in being attenuated in the guinea-pig, susceptible to h2o2, sensitive to thiophen-2-carboxylic acid hydrazide and resistant to thiacetazone and p-aminosalicylic acid; the content of strongly acidic lipids and of sulphatide lipids was low and the attenuation indicator ... | 1978 | 80440 |
| [efficacy of culture and biological studies of patients with destructive pulmonary tuberculosis undergoing chemotherapy]. | | 1978 | 82669 |
| comparison of various preparations of mycobacterium leprae and other mycobacteria by lymphocyte stimulation. | peripheral blood lymphocytes were stimulated in vitro with different mycobacterial antigen preparations and responses were measured as incorporation of tritiated thymidine. blood donors were 9 patients with lepromatous leprosy, 16 tuberculoid leprosy patients, and 6 healthy individuals with different degrees of exposure to leprosy. the results revealed a good correlation between the responses to m. leprae from human sources and bacilli from armadillos inoculated with human leprosy bacilli, altho ... | 1978 | 83309 |
| [primary resistance observed in 974 strains of m. tuberculosis isolated from adult pulmonary patients]. | | 1978 | 84325 |
| evaluation of mycobacteriology laboratories: the acid-fast smear. | in a proficiency testing program, slides bearing acid-fast bacilli were sent to laboratories in new york state. the most reliable results were obtained in laboratories using the ziehl-neelsen method. cold staining procedures were less reliable. the auramine-rhodamine fluorescent stain, which produced many false positives, should be confirmed by the ziehl-neelsen procedure. the testing program described can be used to determine whether laboratories perform the acid-fast stain effectively. | 1978 | 84804 |
| [comparison of different methods of detecting mycobacterium tuberculosis during antibacterial therapy]. | | 1979 | 85299 |
| sarcoidosis and mycobacterial l-forms. a critical reappraisal of pleomorphic chromogenic bodies (hamazaki corpuscles) in lymph nodes. | | 1978 | 86180 |
| [experiments for the serological establishment of the species of mycobacteria inducing an immune restructuring of the macroorganism]. | serological investigations are carried out on hyperimmune rabbit and guinea pig sera with two antigens each of mycobacterium tuberculosis h37rv, mycobacterium bovinus, mycobacterium avium and mycobacterium kanzassi. one of the antigens is obtained through electrohydraulic destruction of delipidated mycobacteria, while the other constitutes cell walls, purified with ribonuclease, of non-delipidated mycobacterial cells, destroyed by the same method. the antigens, prepared by the electrohydraulic m ... | 1978 | 87060 |
| lipid-modified antigens. i. specificity of guinea pig t lymphocyte responses and i-region restriction. | | 1979 | 87434 |
| sputum-smear-negative pulmonary tuberculosis: controlled trial of 3-month and 2-month regimens of chemotherapy. | of 1072 chinese patients with radiographically active pulmonary tuberculosis and no microscopic evidence of acid-fast bacilli in sputum examinations, only 691 (64%) were sputum-culture negative. all patients were randomly allocated to selective chemotherapy (antituberculosis chemotherapy not being started until the activity of the disease had been confirmed), to daily streptomycin, isoniazid, rifampicin, and pyrazinamide for 2 months or 3 months, or to a standard 12-month control regimen. during ... | 1979 | 87829 |
| tuberculosis chemotherapy--how long. | | 1979 | 87838 |
| evaluation of the chloride and bromide salts of cetylpyridium for the transportation of sputum in tuberculosis bacteriology. | the usefulness of cetylpyridium chloride and cetylpyridium bromide, at a final concentration of 1% in 1% solution of sodium chloride, for the transportation of sputum in tuberculosis bacteriology, was evaluated. it was found that these compounds did not alter the staining properties nor the viability of the tubercle bacilli for at least 14 days. | 1979 | 88109 |
| mycobacterial antigens: a review of their isolation, chemistry, and immunological properties. | | 1978 | 88663 |
| [use of herman's method of staining mycobacterium tuberculosis]. | | 1979 | 89264 |
| the influence of decalcifying fluids on the demonstration of mycobacterium tuberculosis in paraffin sections. | | 1979 | 89611 |
| [present state of resistance to antibiotics by tuberculous bacilli in africa (author's transl)]. | tuberculous bacilli isolated from recently infected patients from various african countries, are resistant to the main specific antibiotics. the present study analyses these resistances which are frequent and mainly directed against inh and streptomycin. resistance against inh is frequently associated, and is due to inadequate monitoring of the treatment. the resistance against streptomycin is probably due in part to the frequent use of streptomycin against common non-tuberculous infections. the ... | 1979 | 91079 |
| [diagnostic value of microbiological methods of detecting the causative agent of tuberculosis in studying sputum of varying character]. | | 1979 | 91711 |
| basic mechanisms of chemotherapy. | | 1979 | 92392 |
| the chemotherapy of pulmonary tuberculosis: a review. | | 1979 | 92393 |
| [the efficiency of cold staining methods at the light microscopical evidence of acid fast bacilli (author's transl)]. | comparing studies has been demonstrated wether or not the cold staining of acid fast bacilli is qualitative and quantitative better than the ziehl-neelsen-method. the hot staining was superior to all cold staining methods and their modifications tested. if a cold staining is necessary two methods are recommended, the kinyoun method and the staining with carbolfuchsin which chloroform is added to. thin smear and homogeneous material provide better results. additional investigations concerning dec ... | 1979 | 92862 |
| [commission on screening and diagnostic methods: sputum samples spread on the slide but not fixed: study with the intent of staining and culturing tubercle bacilli]. | | 1979 | 93499 |
| comparison of auramine-rhodamine b and acridine orange for staining of acid-fast bacteria. | in cooperation of 6 laboratories in czechoslovakia and in the gdr, the efficiency of auramine-rhodamine b (ar) and acridine orange (ao) (short-time method) for staining of acid-fast bacilli was compared. whereas a former comparison of ar and ao (original method) pointed out the superiority of ar, the investigation of both methods used as short-time procedures showed significantly more acid-fast rods after using ao. the number of "false positive" results was somewhat higher on ar staining. howeve ... | 1979 | 93610 |
| cellular immunity in patients with tuberculosis caused by mycobacterium kansasii and mycobacterium tuberculosis. | | 1979 | 94081 |
| macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. viii. cinephotomicrographic studies. | t cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. the formation of clusters is antigen-specific. time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. the central lymphocyte attaches through a broad base to the macrophage during the first few hours of incubation. after several hours, during which the central lymphocyte is situated alone on th ... | 1979 | 94460 |
| macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. ix. antigen-pulsed macrophages as a tool for specific absorption of cluster-initiating t cells. | t-cell populations from guinea-pigs sensitized to the protein antigens purified protein derivative of mycobacterium tuberculosis, ovalbumin, or horseradish perioxidase can be selectively depleted of cells capable of initiating antigen-specific macrophage-lymphocyte clusters in vitro. the depletion is achieved by incubating the t cells on a monolayer of antigen-pulsed macrophages in a petri dish for some hours and then gently aspirating the cells not adhering to the bottom of the dish. when subse ... | 1979 | 94461 |
| primary and secondary resistance of mycobacterium tuberculosis in eastern botswana. | of 51 patients in eastern botswana who denied previous anti-tuberculosis treatment, 6 (11.8 %) were excreting tubercle bacilli resistant to one of the first-line drugs in regular use: 4 patients (7.8 %) showed resistance to isoniazid, 2 (3.9 %) to thiacetazone and none to streptomycin. of 44 patients known to have been on previous anti-tuberculosis treatment, 31 (70.5 %) were found to show resistance to one or more of the first line drugs: 31 (70.5 %) to isoniazid, 12 (27.2 %) to streptomycin an ... | 1979 | 94476 |
| the chemical nature of the antigen-specific moiety of transfer factor. | | 1979 | 95068 |
| selective platelet immune retention. | inbred rats were immunized with freund's adjuvant containing proteins of mycogacterium tuberculosis, mycobacterium butyrium, or dinitrochlorobenzene (dncb). native arterial blood was then passed over glass beads coated with those antigens. the platelet retention on the glass beads was measured. rats immunized with complete freund's adjuvant developed accelerated platelet retention on beads coated with protein derivatives of tuberculosis (ppd) after just 18 seconds of blood flow. rats immunized t ... | 1978 | 96007 |
| mode of action of anti-tubercular drugs. | | 1977 | 96023 |
| modification of methods used in bacteriophage typing of mycobacterium tuberculosis isolates. | a procedure in which soft agar overlays were used in bacteriophage-typing mycobacterium tuberculosis is presented. this safer method uses commercially available media, whereas media presently used must be prepared in the laboratory. single plaque isolations of the phage bg-1 specifying phage type a and b of m. tuberculosis were readily made by using the modified procedures. this purification and the use of prototype strain myc 1415 as the indicator host strain have significantly enhanced the abi ... | 1978 | 96127 |
| comparison of several culture media used for studies on mycobacteriophages. | the value of rva, n-1, 7h10, 7h11 and sauton's media for studies on mycobacteriophage infeciton and lysis of mycobacteria was assessed. experiments were made with mycobacteriophages bgi, bki, cri-3, g37, and lg, all of which lyse mycobacterium smegmatis strain 607b, and with mycobacteriophage ds6a which lyses mycobacterium tuberculosis strain h37rv. the methods involved "direct lysis", the measurement of "routine test dilutions" and counts of plaque-forming units. it was found that n-1, 7h10 and ... | 1978 | 96257 |
| [cross resistance in mycobacteria--biochemical and genetic aspects (author's transl)]. | | 1978 | 96293 |
| [skin sensitivity to battey and kansasii sensitins in a selected rural population and students. ii. skin sensitivity to kansasii sensitin and rt-23 tuberculin simulatneously]. | | 1978 | 96432 |
| [tuberculin reactions in guinea pigs injected with virulent and avirulent tubercle bacilli]. | | 1978 | 96433 |
| [meningoencephalitis as an evolutive conplication of hodgkin's disease]. | | 1978 | 96497 |
| [studies of pyrazine derivatives. vi. synthesis and tuberculostatic activity of 6-alkoxy and 6-phenoxy pyrazine-2-carbothioamides]. | | 1978 | 96662 |
| antigenic relationships of various mycobacterial species with mycobacterium tuberculosis. | antigen cross reactivity of various mycobacterial sonicates with mycobacterium tuberculosis was studied by fused rocket immunoelectrophoresis using 2 mycobacterium tuberculosis reference antisera. a considerable degree of cross reactivity was noted with both antisera, and each anti-serum revealed different information about the antigenic complexities between mycobacteria. | 1978 | 96711 |
| tryptophan uptake by mycobacterium tuberculosis h37rv: effect of rifampin and ethambutol. | uptake of radioactive tryptophan by mycobacterium tuberculosis h(37)rv grown in vitro and in vivo was investigated. k(m) values indicated low affinity, and sodium azide inhibited uptake. rifampin at the minimal inhibitory concentration had no effect, whereas ethambutol inhibited uptake only in the bacilli grown under in vitro conditions. the significance of these results is discussed. | 1978 | 96733 |
| a new experimental model of systemic connective tissue disease in immunized rabbit. | in rabbit, the immumizations with whole mycobacterium tuberculosis injected intradermally and its crude cytoplasmic w.s.e. injected intraarticulary induce not only a self-perpetuating synovitis in the stimulated knee but also chronic systemic lesions of connective tissue (non-stimulated knee, both shoulders, aortic artery adventitial valvular endocardium, liver, kidneys and lungs). w.s.e. stimulates precipitating antibody synthesis, skin reaction and lymphoblastic transformation of lymphocytes i ... | 1978 | 96883 |
| studies on transfer rna from mycobacteria. | active preparations of trna and aminoacyl-trna synthetases have been isolated from exponentially growing cells of mycobacterium smegmatis and mycobacterium tuberculosis h37rv. though the aminoacyl-trna synthetases of older cells retain their activity, the trnas seem to undergo modification and show poorer activity. the mycobacterial enzyme preparations catalyse homologous and heterologous aminoacylation between trna from the two species (m. smegmatis and m. tuberculosis h37rv) or from escherichi ... | 1978 | 96929 |
| test for differentiation of m. tuberculosis and m. bovis from other mycobacteria. | a test is described for selective inhibition of mycobacterium tuberculosis and m. bovis isolates in fluid medium. the method employs rho-nitro-alpha-acetyl-amino-beta-hydroxy-propiophenone (nap) as an inhibitory agent for differentiation of mammalian tuberculosis strains from other mycobacteria. | 1978 | 96930 |
| evaluation of diagnostic criteria in tuberculous meningitis in children, including the hemagglutination test on the cerebrospinal fluid. | | 1977 | 97215 |
| activity of amikacin against mycobacterium tuberculosis. | | 1978 | 97261 |
| characterization of the purified components of a new homologous series of alpha-mycolic acids from mycobacterium tuberculosis h37ra. | homologous series of alpha-mycolic acids from mycobacterium tuberculosis h37ra were separated according to size as their p-bromophenacyl ester by bonded c18 reverse-phase, high performance liquid chromatography. mass spectrometry of the prominent components separated by high performance liquid chromatography gave relatively simple spectra and showed a series of components differing by 28 atomic mass units. a total of different structures were identified. the structures were established as follow ... | 1978 | 97292 |
| mycolic acids. a reinvestigation. | mycolic acids derived from the cell walls of mycobacterium bovis bcg, mycobacterium bovis bovinus i, mycobacterium smegmatis, and mycobacterium tuberculosis h37rv have been fractionated as their p-bromophenacyl esters by a two-step high performance liquid chromatographic procedure: 1) adsorption chromatography on 10-micrometer particle size silica gel, and 2) reverse phase partition chromatography on a 10-micrometer particle size support containing a c18 bonded phase. this procedure has resulted ... | 1978 | 97301 |
| nitrate reductase activity of mycobacterium tuberculosis and mycobacterium bovis in the presence of electron donors. | the activities of the nitrate reductase enzyme of mycobacterium tuberculosis, m. bovis, and of bcg were assayed with and without addition of electron donors. m. tuberculosis always reduced nitrate; m. bovis did so only in the presence of electron donors, and bcg did not show enzymatic activity. | 1978 | 97306 |
| cerebral prostaglandin synthesis during the dietary and pathological stresses of essential fatty acid deficiency and experimental allergic encephalomyelitis. | rats of the lewis strain were fed diets adequate or deficient in essential fatty acids (efa). at 70-80 days of age experimental allergic encephalomyelitis (eae) was induced using adjuvants containing either mycobacterium butyricum or mycobacterium tuberculois h37ra. when the former mycobacterium was used, the incidence of eae was greater in the efa-deficient than in efa-adequate controls; but when the rats challenged with m. tuberculosis, the incidence of the disease was the same in both dietary ... | 1978 | 97486 |
| [study of specific sensitivity of the erythrocytes in pulmonary tuberculosis]. | | 1978 | 97657 |
| [chemotherapy of tuberculosis with controlled viability of mycobacteria in the sputum]. | | 1978 | 97658 |
| [method of increasing the effectiveness of the passive phosphatide hemagglutination test]. | | 1978 | 97659 |
| [method of rapid determination of the cord factor in the mycobacterium colonies on solid nutrient medium]. | | 1978 | 97660 |
| [action of streptomycin-group preparations on experimental tuberculosis caused by sensitive and resistent mycobacterium tuberculosis]. | | 1978 | 97661 |
| [virulence of rifampicin-resistent mycobacterium tuberculosis]. | | 1978 | 97662 |
| [virulence of h37rv cultures treated with mycobacteriophages]. | | 1978 | 97663 |
| [quantitative method of assessing the virulence of mycobacterium tuberculosis in an experiment on guinea pigs]. | | 1978 | 97664 |
| antimycobacterial antibodies in tuberculosis. i. the counterimmunoelectrophoresis (cie) test. | | 1978 | 97743 |
| [derivatives of 2-thion-3-isonicotinoylamino-thiazolid-4-one with tuberculostatic activity]. | | 1978 | 97745 |
| [tuberculosis and mycobacteriosis in cattle in the province of santander]. | | 1977 | 97771 |
| [character of bacillus elimination in patients with freshly detected pulmonary tuberculosis]. | | 1978 | 97865 |
| effect of low temperature on growth, viability, and synthesis of mycolic acids of mycobacterium tuberculosis strain h37ra. | cultures of mycobacterium tuberculosis strain h37ra were grownto early logarithmic phase at 37 degrees c and were incubated at 16 degrees, 20 degrees, and 25 degrees c. the decrease in this ability was more rapid at 20 degrees c than at 16 degrees c. low-temperature incubation caused decreases in the ratios of mycolic acids and monounsaturated c16-19 fatty acids relative to the total of fatty acids synthesized. it also caused an increase in the ratio of saturated c24-26 fatty acids relative to ... | 1978 | 98081 |
| niacin-negative strain of mycobacterium tuberculosis. | | 1978 | 98083 |
| enhancing effect of passive immunization with mycobacterial antibodies on humoral and cellular immunity in bcg-infected mice. | the present paper is an attempt to get insight about the mechanisms involved in the enhancing phenomenon that occurs in bacterial infections. mice infected with small doses of the bcg strain of m. bovis and treated with a m. tuberculosis h37rv antiserum investigated at various intervals for their capacity to synthesize haemagglutinating antimyco-bacterial antibodies and to develop delayed hypersensitivity to ppd. as controls, bcg-infected mice were treated with the antiserum freed from its mycob ... | 1978 | 98097 |
| identification and drug sensitivity of tubercle bacilli from addis ababa, ethiopia. | | 1978 | 98117 |
| manipulations of the phagosome-lysosome fusion response in cultured macrophages. enhancement of fusion by chloroquine and other amines. | | 1978 | 98333 |
| host-parasite relationships in experimental airborne tuberculosis. vii. fate of mycobacterium tuberculosis in primary lung lesions and in primary lesion-free lung tissue infected as a result of bacillemia. | evidence suggests that in humans tuberculous disease usually arises at apical or subapical sites in the lungs seeded as a consequence of an early bacillemic phase of the infection. this study examined the fate of bacilli transported via the bloodstream to metastatic sites in the lungs of guinea pigs after aerosol infection with approximately two viable virulent mycobacterium tuberculosis. the results revealed that, even after logarithmic-phase multiplication of bacilli in primary lesions had bee ... | 1978 | 98601 |
| drug-resistant tuberculosis. | | 1978 | 98637 |
| [a new therapeutic approach to open pulmonary tuberculosis with a combination of isoniazid, prothionamid and dapson (author's transl)]. | | 1978 | 98759 |
| differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions. | guinea pigs were sensitized with heat killed m. tuberculosis, m. kansasii, m. scrofulaceum, and m. avium-intracellulare. purified protein derivatives (ppds) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. the homologous reactions were consistently more intense than heterologous reactions in all three procedures. the skin test procedure was more sensitive than either in ... | 1978 | 98814 |
| experimental data on the antimicrobial activity of isoprodian (pth). | | 1978 | 98838 |
| frequency and epidemiology of primary drug-resistance in tuberculosis in the federal republic of germany including berlin (west). partial result of a study of the w.a.t.l. | | 1978 | 98839 |
| the conversion of sputum in tuberculosis. | | 1978 | 98840 |
| [tuberculosis infection]. | | 1978 | 98846 |
| differentiation of bcg from other variants of mycobacterium tuberculosis isolated from clinical material. | bcg isolated from clinical material may be reliably differentiated from other variants within the species mycobacterium tuberculosis by means of a few simple cultural and biochemical tests and by bacteriophage typing. animal pathogenicity tests may therefore be avoided. | 1978 | 98878 |
| [antitumor activity of the bacterial walls of br. abortus 99]. | a brief chronologic survey is made of investigations that reveal that the bacterial cell walls and their chemical components exhibit antitumoral activity. discussed is the problem which are the constituents of the bacterial wal and what is the mechanism through which such effects are produced. the conclusion is drawn that some peptides participating in the structure of the bacterial wall after their release in body stimulate the macrophages and thus confer antitumoral activity to them. | 1978 | 98899 |
| delayed hypersensitivy and experimental interstitial pneumonitis. | the effects of prior sensitization with killed h37ra tubercle bacilli on the pulmonary reaction to intravenous (iv) challenge with complete freund's adjuvant (cfa) have been studied and were compared to reactions in nonsensitized cfa-challenged controls. rabbits that died within 24 hours of challenge demonstrated acute arteritis prior to granuloma formation. sensitized rabbits had a greater number of exudative cells in the pulmonary lavage fluid and a larger volume of parenchymal infiltrate than ... | 1978 | 99116 |
| [studies on the antituberculous activities of rifampicin (rep) and the period of exposure in vitro (author's transl)]. | | 1978 | 99200 |
| [the effects of antituberculous chemotherapy in vitro under various conditions inadequate for the growth of tubercle bacilli (author's transl)]. | | 1978 | 99201 |
| the suppression of the appearance of bacterial mutants by combined antibacterial therapy. | | 1978 | 99422 |
| virulence of mycobacterium tuberculosis and susceptibility to peroxidative killing systems. | at sub-bactericidal concentrations of hydrogen peroxide, mycobacterium tuberculosis was killed by hydrogen peroxide/peroxidase/halide microbicidal systems. the halide cofactor could be either iodide or, with much lower efficiency, chloride. omission of any one of the reactants eliminated the tuberculocidal effect. differences in susceptibility between different strains of m. tuberculosis did not correlate with virulence differences. the observations are discussed in the context of host defence m ... | 1978 | 99484 |
| [prediction of time of terminating chemotherapy and of indication of surgical treatment for pulmonary tuberculosis based on bacteriological findings obtained from resected specimens (author's transl)]. | | 1978 | 99593 |
| [pilot trial of a short-term treatment of leprosy by combined chemotherapy and immunotherapy]. | | 1977 | 99787 |
| tuberculosis infection and the repeat test. effect in bcg-vaccinated guinea pigs. | groups of bcg-vaccinated guinea pigs were infected with mycobacterium tuberculosis and the course of tuberculin reactions before and after was studied. the infection led to reactions that were accelerated as if repeated tests had been given, but were larger than in such cases. acceleration of reactions due to previous testing was present 1 week, but not 4 weeks after the start of the infection. possibly, in cellular immunity in general, absence of the repeat test effect may be interpreted as a s ... | 1978 | 99809 |