| degradative enzymes of oral streptococci. | members of the streptococcus sanguis group (ssg) and streptococcus milleri group (smg) were screened for their ability to produce glycosidase, arylamidase (peptidase), protease, dextranase and glycosyltransferase activities. species within each group produced unique patterns of activity. the most commonly produced glycosidases were beta-d-glucosidase, beta-d-galactosidase, n-acetyl-beta-d-glucosaminidase and n-acetyl-beta-d-galactosaminidase and the least commonly produced glycosidase activity w ... | 1995 | 7786231 |
| increased susceptibility of rag-2 scid mice to dissemination of endodontic infections. | specific immunity has been implicated in the pathogenesis of periapical lesions, although the extent to which these mechanisms are actually involved in either protection or destruction of the pulp-periapex complex is yet to be established. to investigate this question we compared periapical-lesion pathogenesis in rag-2 severe combined immunodeficient (scid) mice with immunocompetent control mice following surgical pulp exposure. in order to equalize the bacterial challenge, an infection protocol ... | 1997 | 9284152 |
| [bacteremias due to the streptococcus milleri group. an analysis of 18 episodes]. | to study the epidemiological and clinical characteristics of bacteremia caused by streptococcus milleri group streptococci (smg). | 1997 | 9304128 |
| dental implant infections. | dental implants provide a restorative tool to support crowns, bridge abutments, and removable dentures. osseointegrated implants are titanium posts that are surgically implanted in alveolar bone. a tight immobile bond (osseointegration) forms between bone and titanium, and prosthetic and restorative fixtures are attached to the implants. titanium implants differ from natural teeth, which may make them more susceptible to mechanical stress. a small proportion of implants are not successful and ma ... | 1997 | 9310682 |
| experimental endocarditis induction and platelet aggregation by streptococcus anginosus, streptococcus constellatus and streptococcus intermedius. | a total of 18 'streptococcus milleri' strains including the atcc type strains of streptococcus anginosus, streptococcus constellatus and streptococcus intermedius were compared with streptococcus oralis atcc10557 for their ability to induce infective endocarditis in catheterized rats. three days after intravenous injection of 10(8) colony-forming units all 8 s. anginosus strains tested produced infective vegetations and bacteremia in almost all rats whereas 5 s. constellatus strains and the s. o ... | 1997 | 9322066 |
| dna-dna hybridization studies and phenotypic characteristics of strains within the 'streptococcus milleri group'. | twenty-five strains resembling 'streptococcus milleri' were compared by dna-dna hybridization, by whole-cell-derived polypeptide patterns on sds-page, and by biochemical tests. four homology groups were revealed by dna-dna hybridization. dna homology groups 1, 2 and 3 were closely related and contained the type strains ncdo 2226 (streptococcus constellatus), ncdo 2227 (streptococcus intermedius) and nctc 10713 (streptococcus anginosus), respectively. dna homology group 4 consisted of four strain ... | 1989 | 2632666 |
| a conserved region of a hyaluronidase gene from streptococcus intermedius. | | 1997 | 9331765 |
| intermedilysin. a cytolytic toxin specific for human cells of a streptococcus intermedius isolated from human liver abscess. | | 1997 | 9331766 |
| degradation of immunoglobulin g by periodontal bacteria. | several subgingival microorganisms were tested for their ability to utilize human immunoglobulin g (igg) as a substrate for growth. this was done using a protein-free chemically defined medium, supplemented with igg. stimulation of growth was observed for capnocytophaga ochracea, porphyromonas asaccharolytica, porphyromonas endodontalis, porphyromonas gingivalis, prevotella intermedia, prevotella oralis, lactobacillus catenaforme and streptococcus intermedius. immunoelectrophoresis, sodium dodec ... | 1994 | 7870469 |
| hyaluronidase activity in human pus from which streptococcus intermedius was isolated. | hyaluronidase (haase) activity was detected in both a human pus sample and the culture supernatant of the only bacterial isolate from the pus, streptococcus intermedius, using a zymographic technique. the optimum ph range for haase activity was similar for both samples. although the bands showing the strongest haase activity of these samples differed from each other with respect to molecular size, both samples were equally inhibited by an antiserum raised against haase of s. intermedius. these r ... | 1997 | 9403504 |
| [abscess of the psoas muscle: analysis of 11 cases and review of the literature]. | abscess of the psoas muscle (ap) is an infrequent disease of difficult diagnosis, developing spontaneously (primary ap) or by extension of a subjacent infection (secondary ap). in recent years changes have been observed in its etiology, advances in its diagnosis and modifications in the treatment schedules. | 1998 | 9542304 |
| [a patient with streptococcus intermedius brain abscess treated with high dose penicillin g--susceptibility of the isolate to penicillin g and the concentration of penicillin g in cerebrospinal fluid]. | we report here a 2-year-old boy with a streptococcus intermedius brain abscess and bilateral ventriculitis successfully treated with a high dose penicillin g (200,000 u/kg/dose, 6 times a day, 1 hour continuous infusion). although hydrocephalus residuced, the high dose penicillin g therapy cured his brain abscess and bilateral ventriculitis. the minimal inhibitory concentration of penicillin g to the isolate was 0.008 microgram/ml. the penicillin g concentration in the cerebrospinal fluid after ... | 1998 | 9621570 |
| two cases of lateral sinus thrombosis presenting with extracranial head and neck abscesses. | two cases of lateral sinus thrombosis in fit adults with no previous otological history are presented. one case occurred in association with bezold's abscess and followed mastoiditis which was masked by previous antibiotic treatment. the other case occurred in association with an occipitoparietal scalp abscess and there was no obvious preceding middle ear infection. the causative bacteria were streptococcus milleri and a variant streptococcus intermedius. lateral sinus thrombosis is discussed. | 1994 | 7964144 |
| human transferrin as a source of iron for streptococcus intermedius. | streptococcus intermedius is well known to produce severe infections in various areas of the body. in this study, we evaluated the ability of s. intermedius to utilise human transferrin as a source of iron and investigated the mechanism by which iron can be obtained from this plasma protein. adding either ferrous sulfate or holotransferrin to an iron-deficient culture medium allowed growth of s. intermedius. cultivation of s. intermedius under an iron-poor condition was associated with the over ... | 1998 | 9741090 |
| bactericidal effects of povidone-iodine solution to oral pathogenic bacteria in vitro. | seven species of periodontal pathogenic bacteria (bacteroides, gingivalis, bacteroides intermedius, bacteroides melaninogenicus, fusobacterium nucleatum, actinobacillus actinomycetemcomitans, capnocytophaga spp., eikenella corrodens) and two control species (streptococcus intermedius, pseudomonas aeruginosa) were selected in order to study the bactericidal effects of 10% povidone-iodine (pvp-i) aqueous solution in vitro. the pvp-i solution was diluted to 10, 20, 50, 100, 200, 400, 800, 1600, 320 ... | 1993 | 8290445 |
| mechanisms of successful amoxicillin prophylaxis of experimental endocarditis due to streptococcus intermedius. | prophylaxis with amoxicillin (40 mg/kg) was studied in rats with aortic valve vegetations. bacteria on the valves were quantitated early (10 min to 6 hr) and late (three days) after intravenous challenge with tolerant streptococcus intermedius. amoxicillin reduced by 40% the number of bacteria per valve 10 min after intravenous challenge with 10(5) s. intermedius (p less than .05) and by 74% the incidence of endocarditis three days thereafter (p less than .0001). bacterial multiplication started ... | 1986 | 3490521 |
| degradation and utilisation of chondroitin sulphate by streptococcus intermedius. | streptococcus intermedius, part of the 'streptococcus milleri group', has the ability to produce glycosaminoglycan depolymerising enzymes (hyaluronidase and chrondroitin sulphate depolymerase) which is unique amongst the viridans streptococci and may contribute to their virulence in brain and liver abscesses. the growth of s. intermedius strain uns 35 was studied in basal medium supplemented with chondroitin sulphate a (cs-a, sulphated at position 4 of the n-acetylgalactosamine moiety) or chondr ... | 1996 | 8636952 |
| [clinical evaluation of lung abscess diagnosed by transtracheal aspiration]. | we have diagnosed lung abscess according to findings of infiltration with cavity formation on chest x-ray and/or ct-scan and pathogens isolated from transtracheal aspirates. we evaluated the clinical features of 20 patients with lung abscess (18 males and 2 females, mean age; 54.3 years). diabetus mellitus and periodontal diseases were prominent underlying diseases in patients with lung abscess. cough was complained in 13 patients, chest or back pain in 9, purulent sputum in 8 and hemosputum in ... | 1998 | 9884505 |
| microaerophilic streptococci as a significant pathogen: a twelve-year review. | one hundred twenty three microaerophilic streptococci (ms) were isolated from 4,603 specimens submitted for the identification of anaerobic bacteria over the course of 12 years. the ms included 16 streptococcus constellatus, 43 streptococcus intermedius and 21 gemella morbillorum. a total of 81 ms isolates (66%) identified from 75 patients were considered to cause infection. predisposing or underlying conditions were noted in 48 (64%) patients. the most common conditions were previous surgery (1 ... | 1994 | 7996059 |
| production of specific glycosidase activities by streptococcus intermedius strain uns35 grown in the presence of mucin. | an isolate of streptococcus intermedius from a brain abscess showed neuraminidase (sialidase), beta-d-galactosidase, n-acetyl-beta-d-glucosaminidase and n-acetyl-beta-d-galactosaminidase activities. the optimal ph values of these enzymes were 5.5-6.0, 5.5-6.0, 5.0-5.5 and 5.0-5.5, respectively. the km of the enzymes varied according to whether the type of substrate was chromogenic or fluorogenic; sialidase was most active at the lowest substrate concentrations, with a km of 0.01 mm. in semi-defi ... | 1994 | 8064838 |
| clinical and microbiological characteristics of smokers with early onset periodontitis. | cigarette smoking is a potential risk factor which has recently been associated with periodontal disease progression. the objective of this study was to compare the microbial profile of smokers and non-smokers in a group of patients with early onset periodontitis. the study population consisted of 60 healthy individuals, 40 males and 20 females aged 22 to 35 yr, exhibiting early onset periodontitis. thirty patients were smokers (30.9 cigarettes/d) and 30 non-smokers. smokers had a higher proport ... | 1999 | 10086883 |
| purification and properties of a novel glycosaminoglycan depolymerase from streptococcus intermedius strain uns 35. | a glycosaminoglycan (gag) depolymerase that acts on chondroitin sulphate a (cs-a), chondroitin sulphate c (cs-c) and hyaluronic acid (ha) was purified to apparent homogeneity from a culture of streptococcus intermedius, strain uns 35, grown in minimal medium supplemented with cs-a as the sole carbon source. the enzyme was purified by ammonium sulphate precipitation followed by serial chromatography on deae trisacryl m, cm trisacryl m and heparin-agarose. sds-page analysis of the purified enzyme ... | 1996 | 8636953 |
| evidence for the generation of specific t suppressor lymphocytes by streptococcus intermedius. | crude extracellular products of the streptococcus intermedius "cep-si" were able to strongly decrease the in vitro proliferation of stimulated human peripheral blood mononuclear cells (hpbmc) when evaluated by (3h)-thymidine and (3h)-leucine uptake. on the other hand, cep-si only slightly decreased this proliferation when hpbmc were either not stimulated or cultured in poor conditions or immature cells, i.e. thymocytes were used as target instead. also in vivo cep-si was ineffective when target ... | 1983 | 6191807 |
| [acute suppurative thyroiditis due to streptococcus intermedius]. | | 1999 | 10193011 |
| abscess forming ability of streptococcus milleri group: synergistic effect with fusobacterium nucleatum. | the abscess forming abilities of "streptococcus milleri" strains (streptococcus constellatus, streptococcus anginiosus, and streptococcus intermedius) isolated from dentoalveolar abscesses and the synergistic effect of fusobacterium nucleatum co-inoculated with the isolates were examined on a mouse subcutaneous abscess model. five days after inoculation, all s. milleri strains formed abscesses, which showed less pathological spread to surrounding connective tissues than those formed by staphyloc ... | 1999 | 10338189 |
| antigenic relationships and rapid identification of peptostreptococcus species. | antisera against whole cells of each peptostreptococcus species (p. anaerobius, p. micros, p. parvulus, and p. productus) were produced in rabbits. when these antisera were reacted against sonically disrupted cells and culture supernatant fluids in ouchterlony tests, lines of identity were obtained among the antigens from all the species and uninoculated culture medium. when the antisera were subsequently absorbed with the dehydrated culture medium used to grow the peptostreptococci, all cross-r ... | 1980 | 6769956 |
| anaerobic bacteria in dentoalveolar infections. | the bacteriology of 57 dentoalveolar infections was studied using optimal techniques to collect, transport and process specimens. there was an average of 4 bacterial species per specimen, and only 1/3 of the specimens held aerobes. among the aerobic bacteria, streptococci dominated and among the anaerobes the gram-negative rods, bacteroides ruminicola and fusobacterium nucleatum, were most frequently isolated followed by gram-positive cocci, in particular streptococcus intermedius. all aerobic i ... | 1981 | 6807917 |
| trichosporon beigelii fungemia and cutaneous dissemination. | trichosporon beigelii fungemia and multiple, purpuric, papular skin lesions developed on the chest wall and extremities of a 22-year-old man with acute granulocytic leukemia. histologically, the skin lesions demonstrated dermal budding yeasts, which were identified as t beigelii in culture. unexplained biventricular, congestive heart failure and sepsis wit streptococcus intermedius developed, and the patient died 28 days after his admission to the hospital. | 1982 | 6952820 |
| infection-stimulated infraosseus inflammation and bone destruction is increased in p-/e-selectin knockout mice. | infections of the dental pulp commonly result in infraosseus inflammation and bone destruction. however, the role of phagocytic leucocytes in the pathogenesis of pulpal infections has been uncertain. in this work we used p/e-/- selectin-deficient mice, which lack rolling adhesion of leucocytes to endothelium and mimic the human syndrome, leucocyte adhesion deficiency ii (lad-ii), to test the hypothesis that phagocytic leucocytes protect against pulpal infection and subsequent periapical infraoss ... | 1999 | 10447722 |
| production of deoxyribonuclease, ribonuclease, coagulase, and hemolysins by anaerobic gram-positive cocci. | clinical isolates of peptococcus and peptostreptococcus species and streptococcus intermedius strains were obtained from local hospitals. after confirmed identification, each isolate was tested for the in vitro production of deoxyribonuclease, ribonuclease, coagulase, and hemolysins. of the 60 strains studied, 18 had enzymatic activity. the variability of enzyme production suggests that such assays are not suitable as an aid to identification of these organisms. | 1981 | 7229018 |
| streptococcus intermedius-brain abscess in chronic granulomatous disease. | | 1999 | 10486103 |
| isolation of bacteria from cervical lymph nodes in patients with oral cancer. | thirty patients with oral mucosal cancer were studied in relation to oral mucosal damage and bacterial translocation to the regional lymph nodes in the neck. all 30 patients (gingiva 11, tongue 13, cheek mucosa four, oral floor two) underwent extensive, clean-contaminated, head-and-neck surgery (including neck dissection) with free flap reconstruction. a total of 153 lymph nodes was harvested for microbial and histological examination. viable bacteria were isolated from 70 lymph nodes (45.8%) fr ... | 1999 | 10530911 |
| heterogeneity among 16s-23s rrna intergenic spacers of species within the 'streptococcus milleri group'. | the 16s-23s rrna intergenic spacer has been suggested as a suitable region of the bacterial genome from which to derive useful taxonomic information, particularly with regard to identification at the species level. to investigate this approach as an aid to the identification of the three species comprising the 'streptococcus milleri group' (smg), the spacers of isolates of streptococcus intermedius, streptococcus anginosus and streptococcus constellatus were amplified by pcr and length polymorph ... | 1995 | 7545512 |
| intermedilysin, a novel cytotoxin specific for human cells secreted by streptococcus intermedius uns46 isolated from a human liver abscess. | a novel cytotoxin (intermedilysin) specific for human cells was identified as a cytolytic factor of streptococcus intermedius uns46 isolated from a human liver abscess. intermedilysin caused human cell death with membrane blebs. intermedilysin was purified from uns46 culture medium by means of gel filtration and hydrophobic chromatography. the purified toxin was resolved into major and minor bands of 54 and 53 kda, respectively, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. these ... | 1996 | 8757839 |
| distribution of the intermedilysin gene among the anginosus group streptococci and correlation between intermedilysin production and deep-seated infection with streptococcus intermedius. | the distribution of intermedilysin, a human-specific cytolysin, among the anginosus group streptococci and the correlation of toxin production and infection by streptococcus intermedius were investigated. pcr and southern hybridization specific for the intermedilysin gene revealed that the toxin gene exists only in s. intermedius and no homologue to the toxin gene is distributed in s. anginosus and s. constellatus. thus, the intermedilysin gene is useful as a marker gene of s. intermedius. moreo ... | 2000 | 10618091 |
| rapid species identification of "streptococcus milleri" strains by line blot hybridization: identification of a distinct 16s rrna population closely related to streptococcus constellatus. | a collection of 399 "streptococcus milleri" strains were identified to the species level by the use of a line blot assay. their pcr-amplified partial 16s rrna gene sequences were hybridized with species-specific 5'-biotinylated oligonucleotide probes homologous to the bp 213 to 231 regions of the 16s rrna gene sequences of the type strains streptococcus anginosus atcc 33397, streptococcus constellatus atcc 27823, and streptococcus intermedius atcc 27335. the hybridization results were compared w ... | 1996 | 8784576 |
| streptococcus intermedius: a cause of lobar pneumonia with meningitis and brain abscesses. | | 2000 | 10671350 |
| electrophoresis of whole-cell soluble proteins of microorganisms isolated from bacteremias in endodontic therapy. | we have previously demonstrated that anaerobic bacteria are the microorganisms most frequently isolated from blood following endodontic therapy of teeth with apical periodontitis. phenotypic characterisation of the isolates suggested that the bacteria in the blood originated from the root canal. the present experiment using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) was carried out in an effort to verify these findings, and to further study the microorganisms involved i ... | 1996 | 9021323 |
| multiple bilateral cerebral abscesses with hemorrhage. | brain abscess with spontaneous hemorrhage is an uncommon illness. a rare case of multiple abscesses in both cerebral hemispheres complicated by hemorrhage is reported. minimally invasive surgery utilizing magnetic resonance imaging (mri) guidance was performed after extensive testing failed to yield a diagnosis. streptococcus intermedius was isolated from cultures taken during surgery and intravenous antimicrobial therapy was instituted. pathology other than metastatic neoplasms and subacute hem ... | 1997 | 9067848 |
| profile of subgingival microbiota in children with primary dentition. | eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the aim of the study was to investigate the composition of the subgingival microbiota of primary incisors, canines and molars in 40 systemically healthy children aged 4-5 yr, chosen randomly. subgingival plaque samples were taken from the mesiobuccal sites of primary incisors (61, 81), canines (53, 73) and molars (64, 84). the samples were cultured for bacterial isolat ... | 2000 | 10791707 |
| [effects of globulin preparations on phagocytic killing of oral streptococci]. | the phagocytic bacterial activity on streptococcus intermedius and streptococcus oralis, clinical isolates from patients suffering from severe oral surgical infections, was evaluated by using sera and neutrophils of patients who had been treated with polyethylene glycal treated human normal immunoglobulin (venoglobulin-ih). the phagocytic function of the neutrophils against the two strains, approximately 10 cells/neutrophil, was unrelated to the administration of venoglobulin-ih. the bactericida ... | 1997 | 9283142 |
| toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. | c3h/hej mice have an impaired ability to respond to lipopolysaccharide (lps) due to a mutation in the gene that encodes toll-like receptor 4 (tlr4). the effect of tlr4 deficiency on host responses to endodontic infections is unknown. in the present study, we compared periapical bone destruction, sepsis, and inflammatory cytokine production in lps-hyporesponsive c3h/hej and wild-type control c3h/heouj mice. the mandibular first molars of both strains were subjected to pulpal exposure and infectio ... | 2000 | 10899873 |
| the role of hyaluronidase in growth of streptococcus intermedius on hyaluronate. | | 1997 | 9331743 |
| [bacteremia caused by streptococcus intermedius]. | | 1997 | 9382334 |
| b-cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer. | we have previously demonstrated that a high proportion of rag-2 scid knockout mice, which lack t and b cells, develop orofacial abscesses and disseminated infections following pulpal infection, whereas immunocompetent control mice do not. in the present study, we sought to identify the components of the adaptive immune response which contribute to protection against disseminating anaerobic infections and sepsis. for this purpose, various genetically engineered immunodeficient mice were employed, ... | 2000 | 10992465 |
| the splendore-hoeppli phenomenon in hepatic botryomycosis. | a 68 year old diabetic man developed septicaemia and multiple liver abscesses due to streptococcus intermedius. liver biopsy revealed streptococcal botryomycosis which showed the splendore-hoeppli phenomenon. diabetes mellitus is an example of the immunosuppressed states that have been associated with botryomycosis. | 1998 | 9708210 |
| [streptococcus intermedius lemierre syndrome: an unusual association]. | lemierre's syndrome is a potentially severe though uncommon entity consisting in septic emboli from an internal jugular vein thrombus after oropharyngeal infection. | 2000 | 11072359 |
| microbiological parameters associated with il-1 gene polymorphisms in periodontitis patients. | polymorphisms in the cluster of il-1 genes have been significantly associated with the severity of adult periodontitis. the purpose of this study was to compare microbiological parameters in il-1 genotype negative and positive adult subjects with a range of periodontitis severities. | 2000 | 11073323 |
| vibrio cholerae cytolysin: assembly and membrane insertion of the oligomeric pore are tightly linked and are not detectably restricted by membrane fluidity. | hemolytic strains of vibrio cholerae secrete a cytolysin that, upon binding as a monomer, forms pentameric pores in animal cell membranes. pore formation is inhibited at low temperature and in the absence of cholesterol. we here posed the following questions: firstly, can oligomerization be observed in the absence of pore formation? secondly, is membrane fluidity responsible for the effect of temperature or of cholesterol upon pore formation? the first issue was approached by chemical cross-link ... | 2000 | 11118538 |
| [a mitral valve reconstruction of infective endocarditis with brain abscess and intracranial mycotic aneurysm]. | a case is reported of a brain abscess and an intracranial mycotic aneurysm associated with infective endocarditis caused by streptococcus intermedius. a 60-year-old man with a history of fever presented aphasia and right hemiparesis. a computed tomographic scan of the head revealed a low-density area with ring enhancement in the left parietal lobe consistent with a brain abscess. an angiography demonstrated an aneurysm on the distal branch of the middle cerebral artery compatible with a mycotic ... | 1998 | 9750450 |
| profile of subgingival microbiota in children with mixed dentition. | a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ... | 2000 | 11155173 |
| interleukin-6 deficiency increases inflammatory bone destruction. | periapical bone destruction occurs as a consequence of pulpal infection. in previous studies, we showed that interleukin-1 (il-1) is the primary stimulator of bone destruction in this model. il-6 is a pleiotropic cytokine that is induced in these infections and has both pro- and anti-inflammatory activities. in the present study, we determined the role of il-6 in regulating il-1 expression and bone resorption. the first molars of il-6 knockouts (il-6(-/-)) and wild-type mice were subjected to su ... | 2001 | 11159963 |
| growth inhibitory activity of gutta-percha points containing root canal medications on common endodontic bacterial pathogens as determined by an optimized quantitative in vitro assay. | gutta-percha points containing calcium hydroxide, zinc oxide (zno), a mixture of zno and chlorhexidine (zno/chx), iodine-polyvinylpyrrolidone (zno/j-pvp), or a mixture of chx and j-pvp and zno (zno/chx/j-pvp) were tested for their ability to inhibit growth of pure cultures of bacterial species commonly involved in endodontic infections (peptostreptococcus micros, streptococcus intermedius, enterococcus faecalis, and porphyromonas gingivalis). to quantitate growth inhibition, an in vitro assay wa ... | 2000 | 11199764 |
| bilateral tubo-ovarian abscesses four years after total abdominal hysterectomy. | pelvic inflammatory disease (pid) is a common gynecologic disorder. one known complication of pid is tubo-ovarian abscess (toa) formation. the predominant theory on toa formation postulates that an ascending infection from the cervix through the uterus to the fallopian tubes and ovaries results in abscess formation. other theories include seeding via a hematogenous infection, diverticular disease, and appendicitis. | 1998 | 9785111 |
| recovery of anaerobic bacteria from a post-traumatic nasal septal abscess. a report of two cases. | this report presents 2 children (boys, 11 and 9 years old) who had post-traumatic nasal septal abscesses. cultures for aerobic and anaerobic bacteria revealed peptostreptococcuus magnus and a beta-lactamase-producing prevotella intermedia in the first patient, and peptostreptococcus anaerobius, streptococcus intermedius, and prevotella melaninogenica in the second patient. anaerobic bacteria may play a role in nasal septal abscesses. | 1998 | 9823846 |
| risk factors for nosocomial pneumonia in critically ill trauma patients. | to determine risk factors for nosocomial pneumonia in critically ill trauma patients. | 2001 | 11246310 |
| cloning and dna sequencing of the surface protein antigen i/ii (paa) of streptococcus cricetus. | we have cloned and sequenced the gene encoding the surface protein antigen paa (antigen i/ii family) from streptococcus cricetus e49 (serotype a) using degenerate pcr. the deduced amino acid sequence of paa reveals two repeating regions (a region; alanine-rich region, p region; proline-rich region). two additional tandem repeats were found in the a region and part of the p region was deleted compared to antigen i/ii. homology and phylogenetic analyses reveal that paa is homologous to streptococc ... | 2001 | 11267788 |
| antibiotic susceptibilities of genetically characterized streptococcus milleri group strains. | previous studies of the antibiotic susceptibility of streptococcus milleri group organisms have distinguished among species by using phenotypic techniques. using 44 isolates that were speciated by 16s rrna gene sequencing, we studied the mics and minimum bactericidal concentrations of penicillin, ampicillin, ceftriaxone, and clindamycin for streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus. none of the organisms was resistant to beta-lactam antibiotics, although ... | 2001 | 11302819 |
| streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus ("streptococcus milleri group") are of different clinical importance and are not equally associated with abscess. | difficulties in distinguishing organisms of the "streptococcus milleri group" (smg; streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus), have caused ambiguity in determining their pathogenic potential. we reviewed 118 cases in which smg isolates had been identified using 16s rdna sequence. s. constellatus and s. anginosus were isolated far more frequently than was s. intermedius. nearly all isolates of s. intermedius and most isolates of s. constellatus, but only ... | 2001 | 11317256 |
| novel presentation and approach to management of hepatopulmonary syndrome with use of antimicrobial agents. | a 44-year-old man with hepatitis c-associated liver cirrhosis, cyanosis, digital clubbing, and platypnea presented with left-side hemiplegia found to be due to a brain abscess. hepatopulmonary syndrome was diagnosed after demonstration of the presence of a massive intrapulmonary shunt. although the anomalous vascular channel never was defined anatomically, follow-up studies confirmed the presence of a functional shunt. culture of a sample from the abscess yielded streptococcus intermedius. it wa ... | 2001 | 11317264 |
| nonclostridial gas gangrene due to streptococcus anginosus in a diabetic patient. | streptococcus anginosus was recently identified as a distinct species from the other members of streptococcus milleri group (streptococcus constellatus, streptococcus intermedius). we report a rare case of nonclostridial gas gangrene caused by s. anginosus. a 62-year-old diabetic woman was admitted with gas gangrene of the perineal area. she had been taking her oral hypoglycemia medication regularly for 10 years, but the diabetes was inadequately controlled. she was treated with surgical debride ... | 1999 | 10025866 |
| brain abscess caused by streptococcus intermedius: two case reports. | although streptococcus intermedius has been recognized as an important pathogen for abscess formation outside the central nervous system, the streptococcus milleri group, of which it is a member, has not been recognized as a specific pathogen for brain abscess, often thought to be caused by streptococcus viridans, which includes other streptococcal species. | 1999 | 10029431 |
| an in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates. | the bactericidal effect of four antimicrobial agents was investigated against single-species biofilms derived from a range of root canal isolates. | 2001 | 11482142 |
| effect on polymorphonuclear cell function of a human-specific cytotoxin, intermedilysin, expressed by streptococcus intermedius. | streptococcus intermedius is a member of the normal flora of the mouth but is also an opportunistic pathogen associated with purulent infections at oral and nonoral sites. intermedilysin (ily) has been shown to be a cytolysin capable of generating pores in the cell membrane of erythrocytes demonstrable by electron microscopy. this effect has been shown to be specific for human cells. since polymorphonuclear cells (pmns) are the main cell involved in innate immunity we investigated the effect of ... | 2001 | 11553548 |
| extracellular proteins of staphylococcus aureus and the role of sara and sigma b. | staphylococcus aureus synthesizes a large number of extracellular proteins that have been postulated to play a role in bacterial virulence. the proteomic approach was used to analyse the pattern of extracellular proteins of two different s. aureus strains, rn6390 and col. thirty-nine protein spots were identified by n-terminal sequencing or maldi-tof-ms. the differences of the extracellular protein patterns between both strains are striking. among the 18 proteins identified in s. aureus col ther ... | 2001 | 11681202 |
| association of early onset periodontitis microbiota with aspartate aminotransferase activity in gingival crevicular fluid. | the objective of this study was to determine the relationship between the activity of the enzyme aspartate aminotransferase (ast) in gingival crevicular fluid (gcf) using the colorimetric periogard (ptm) test and the subgingival microflora in early onset periodontitis lesions. | 2001 | 11737506 |
| [acute empyema caused by streptococcus milleri in early pregnancy]. | a 40-year-old woman was admitted to our department complaining of left lateral chest pain and fever. she smoked 10 cigarettes per day. chest radiographs revealed increased density in the upper left lung field and air-fluid level in the lower left lung field. a diagnosis of acute empyema was made, because pus was aspirated by thoracentesis. streptococcus intermedius (streptococcus milleri group) was isolated from samples of pleural effusion. the patient was successfully treated with a combination ... | 1999 | 10087875 |
| effect of low-molecular-weight chitosans on the adhesive properties of oral streptococci. | it was previously shown that a low-molecular-weight chitosan and its derivatives n-carboxymethyl chitosan and imidazolyl chitosan inhibit streptococcus mutans adsorption to hydroxyapatite. the ability of the same molecules to interfere with adhesive properties of other oral streptococci (streptococcus sanguis, streptococcus gordonii, streptococcus constellatus, streptococcus anginosus, streptococcus intermedius, streptococcus oralis, streptococcus salivarius, streptococcus vestibularis) was test ... | 1998 | 10093536 |
| evaluation of the automicrobic system for the identification of streptococcus mutans. | the performance of the automicrobic system with the vitek gram-positive identification card (biomérieux, france) in identifying strains of streptococcus mutans was studied. of 160 strains assayed, 72.5% were confirmed to be streptococcus mutans; the remainder were identified as other species of streptocci (streptococcus bovis, streptococcus uberis, streptococcus anginosus, streptococcus sanguis i and ii, streptococcus intermedius, and streptococcus constellatus). | 1995 | 8681990 |
| pathological fracture of the femur secondary to haematogenous osteomyelitis in a weimaraner. | a seven-year-old male weimaraner developed an acute-onset non-weightbearing pelvic limb lameness without a history of significant trauma. radiographs demonstrated an oblique fracture of the femur associated with a lytic bone lesion, while cytology and histopathology of the lesion were consistent with osteomyelitis. a pure growth of streptococcus intermedius was obtained from culture of affected tissue samples. the fracture healed without complication after rigid internal fixation and antibiotic ... | 1999 | 10385869 |
| in-vitro antimicrobial susceptibility of the "streptococcus milleri' group (streptococcus anginosus, streptococcus constellatus and streptococcus intermedius). | a collection of 423 clinical "streptococcus milleri' strains was speciated and tested for susceptibilities to twelve antibiotics. only 1.4% of the strains were of intermediate susceptibility to penicillin. none of the strains exhibited high-level resistance to gentamicin. strains resistant to erythromycin, roxithromycin and clindamycin were found with a frequency of 2.6%, 2.4% and 2.4% respectively. doxycycline resistance was found in 5.7% of the strains and occurred most frequently in streptoco ... | 1996 | 8707750 |
| refractory periodontitis or recurrence of disease. | refractory periodontal disease is characterized by low plaque scores and low responsiveness to periodontal therapy. the patients often have a history of antibiotic therapy and therefore have a high incidence of resistance in the subgingival microflora. the above features are in contrast to adult chronic periodontal disease and recurrence of disease. the subgingival microflora of refractory disease may be either predominantly gram-positive with elevated levels of streptococcus intermedius or may ... | 1996 | 8707992 |
| rapid identification of streptococcus intermedius by pcr with the ily gene as a species marker gene. | streptococcus intermedius belongs to the anginosus group of streptococci (ags) and is associated with endogenous infections leading to abscesses in the oral cavity and at deepseated sites, such as the brain and liver. two other species, s. anginosus and s. constellatus, and some presently unnamed taxa, are also classified as ags. recently, s. constellatus subsp. pharyngis, a new subspecies with biochemical characteristics similar to s. intermedius, was described with the potential for causing co ... | 2002 | 11863269 |
| the streptococcus milleri group as a cause of pulmonary infections. | streptococci that colonize the mouth and upper respiratory tract tend to be considered harmless commensals. in 45 cases of acute pneumonia and/or pulmonary abscess and 25 cases of thoracic empyema, the predominant species recovered were anaerobic bacteria and the streptococcus milleri group, which encompasses the oral species streptococcus anginosus, streptococcus constellatus, and streptococcus intermedius. the isolation of most s. milleri organisms along with oral anaerobes indicated synergy b ... | 1995 | 8749672 |
| brain abscess due to capnocytophaga species, actinomyces species, and streptococcus intermedius in a patient with cyanotic congenital heart disease. | | 2002 | 11957031 |
| streptococcus milleri infection and pericardial abscess associated with esophageal carcinoma: report of two cases. | we report 2 cases of esophageal carcinoma with esophago-mediastinal fistula that developed pericardial abscess due to streptococcus intermedius infection. streptococcus intermedius, a generally harmless commensals in healthy humans, is not usually associated with infections of the oral cavity but may account for non-oral purulent infections. this report, however, highlights that streptococcus intermedius infection can be life-threatening for some patients such as those with esophageal carcinoma ... | 1999 | 10430344 |
| [microflora of the inflammatory erosive areas of the esophagus in esophagitis patients]. | seven patients with erosive esophagitis and reflux esophagitis were examined. in cases of inflammatory erosive phenomena staphylococci, micrococcus luteus, candida, bacteria of the genera pseudomonas, veilonella, klebsiella and other bacteria of the family enterobacteriaceae, as well as helicobacter pylori were detected in different frequency. in most cases concentrations of microorganisms were 4.07-5.39 ig cfu/g. isolated microorganisms producing different pathogenicity enzymes--hemolysin (stre ... | 2002 | 12043159 |
| five-year analysis of antimicrobial susceptibility of the streptococcus milleri group. | susceptibility to 17 antibiotics was studied in 180 strains of the streptococcus milleri group (88 streptococcus anginosus, 63 streptococcus constellatus, and 29 streptococcus intermedius) isolated over a 5-year period. minimum inhibitory concentrations of penicillin were in the intermediate range for 5.6% of the strains. resistance to erythromycin and clindamycin was found in 17.1% and 16.6% of the isolates, respectively. a steady increase in the susceptibility to ciprofloxacin was observed ove ... | 1999 | 10442424 |
| distribution of mef(a) in gram-positive bacteria from healthy portuguese children. | we screened 615 gram-positive isolates from 150 healthy children for the presence of the erm(a), erm(b), erm(c), erm(f), and mef(a) genes. the mef(a) genes were found in 20 (9%) of the macrolide-resistant isolates, including enterococcus spp., staphylococcus spp., and streptococcus spp. sixteen of the 19 gram-positive isolates tested carried the other seven open reading frames (orfs) described in tn1207.1, a genetic element carrying mef(a) recently described in streptococcus pneumoniae. the thre ... | 2002 | 12121926 |
| haemophilus segnis polymicrobial and monomicrobial bacteraemia identified by 16s ribosomal rna gene sequencing. | this paper reports a case of haemophilus segnis polymicrobial bacteraemia and a case of h. segnis monomicrobial bacteraemia identified by 16s ribosomal rna gene sequencing. in the first case, a gram-negative aerobic coccobacillus was isolated with streptococcus intermedius and s. sanguis from the blood culture of a 32-year-old intravenous drug addict with left thoracic empyema. in the second case, a gram-negative aerobic coccobacillus was isolated from the blood culture of an 82-year-old woman w ... | 2002 | 12171293 |
| [cerebral abscess due to streptococcus intermedius resistant to metronidazole: a report of 3 cases]. | | 1999 | 10452152 |
| cloning and expression of hyaluronate lyase genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus(1). | hyaluronate lyase (haase) genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus were isolated. in s. constellatus subsp. constellatus, the deduced amino acid sequence of haase was most similar to that of s. intermedius (68%), whereas the enzyme of s. intermedius was most similar to that of s. pneumoniae (72%). upstream of the haase gene on the opposite strands, an open reading frame of a putative glutathione peroxidase started in s. intermedius, and this arrangeme ... | 2003 | 12594036 |
| typing of candida glabrata in clinical isolates by comparative sequence analysis of the cytochrome c oxidase subunit 2 gene distinguishes two clusters of strains associated with geographical sequence polymorphisms. | we tested whether comparative sequence analysis of the mitochondrion-encoded cytochrome c oxidase subunit 2 gene (cox2) could be used to distinguish intraspecific variants of candida glabrata. mitochondrial genes are suitable for investigation of close phylogenetic relationships because they evolve much faster than nuclear genes, which in general exhibit very limited intraspecific variation. for this survey we used 11 clinical isolates of c. glabrata from three different geographical locations i ... | 2000 | 10618092 |
| development of a clindamycin-impregnated fiber as an intracanal medication in endodontic therapy. | the effectiveness of traditional endodontic intracanal medications in reducing bacterial numbers and preventing acute flare-ups and pain continues to be questioned. in the present study, a new local delivery device was developed that releases a substantive dose of clindamycin into root canals. clindamycin-impregnated ethylene vinyl acetate (eva) fibers were produced, and the sensitivity of common endodontic microbes to the fibers were established. an in vitro model was developed to persistently ... | 1999 | 10726537 |
| additive antimicrobial activity of calcium hydroxide and chlorhexidine on common endodontic bacterial pathogens. | it is an established procedure to use calcium hydroxide [ca(oh)2] as a therapeutic component to achieve sterilization of infected root canals. unfortunately, some bacterial species are relatively resistant to ca(oh)2 and are therefore associated with treatment failures. the objective of this study was to identify combinations of substances that improve antimicrobial activity. ca(oh)2 was used as a suspension or as a component of gutta-percha points. efficacy of killing was compared for (a) ca(oh ... | 2003 | 12775007 |
| subgingival microbiota levels and their associations with periodontal status at the sampled sites in an adult sudanese population using miswak or toothbrush regularly. | little information is available on the effect of miswak use on gingival microbiota. we assessed levels of 28 oral bacteria in subgingival plaque of adult sudanese miswak (n = 38) and toothbrush users (n = 36) age range 20-53 years (mean 34.6 years) to study associations between these bacteria, oral hygiene method, and periodontal status at the sampled sites. a pooled subgingival plaque sample from 6 probing sites of 1 selected tooth in each jaw was obtained from each subject. whole genomic dna p ... | 2003 | 12790510 |
| comparison of three methods for identification of streptococcus milleri group isolates to species level. | a collection of 180 clinical isolates of streptococcus milleri group were identified to species level using two phenotypic methods (a commercial system and the reference method based on differential phenotypic reactions) and a genotypic method (hybridisation of the 16s rrna gene with species-specific probes) in order to evaluate the performance of the respective methods. a high level of agreement (80%) was observed between the results of the reference method and the genotypic method. the highest ... | 2000 | 10746501 |
| pediatric epiglottitis caused by group g beta-hemolytic streptococcus. | | 2003 | 14515840 |
| transverse leukonychia with systemic infection. | transverse white nail bands (leukonychia) have been described in association with systemic illnesses and exposure to toxins, and medications. we describe the occurrence of transverse nail bands in two patients following acute systemic illnesses. in the first case, transverse white nail bands developed in a 30-year-old human immunodeficiency virus-positive man following acute pulmonary tuberculosis. in the second case, transverse white nail bands were noted in an 80-year-old patient following str ... | 2000 | 10826095 |
| [bacteremia, endocarditis and abscess due to streptococcus intermedius]. | | 2003 | 14624664 |
| culture-independent identification of pathogenic bacteria and polymicrobial infections in the genitourinary tract of renal transplant recipients. | renal transplant recipients are predisposed to urinary tract infections caused by both common uropathogens and opportunistic bacteria resulting frequently in significant polymicrobial infections. in this study, a culture-independent 16s rrna-based approach was established to identify unusual, fastidious, or anaerobic bacteria and to investigate bacterial diversity in urinary tract specimens. similarly sized amplicons encompassing the v6 to v8 region of the 16s rrna were analyzed with denaturing ... | 2003 | 14662931 |
| perianal subcutaneous abscess caused by streptococcus intermedius in a patient with multicentric castleman's disease. | | 2000 | 10971504 |
| platelet responses and anaphylaxis-like shock induced in mice by intravenous injection of whole cells of oral streptococci. | intravenous injection of lyophilized whole cells of various oral streptococcal strains into muramyldipeptide (mdp)-primed c3h/hen mice induces rapid anaphylactoid shock. here we examined the mechanism underlying this shock. in non-primed mice, streptococcus intermedius k-213k (sik213) and streptococcus constellatus t21 (sct21) produced little or no sign of shock. in mdp-primed mice, sik213 caused lethal shock, while sct21 only had a weak effect. sik213 induced decreases in blood platelets and 5- ... | 2004 | 14678471 |
| crystallization and preliminary x-ray analysis of the human-specific toxin intermedilysin. | intermedilysin is a human-specific toxin from streptococcus intermedius, which is part of normal human oral flora. the bacterium is an opportunistic pathogen with a tendency for deep-seated infection in the brain and liver. intermedilysin belongs to the cholesterol-dependent cytolysin (cdcs) family of toxins, which have been identified in several different bacteria including the serious human pathogens s. pneumoniae and clostridium perfringens. intermedilysin, however, is the only member that sh ... | 2004 | 14747721 |
| hepatic abscess as a complication of the sump syndrome. | we report a case of hepatic abscess associated with the sump syndrome. the patient was a 66-year-old woman who had undergone cholecystectomy and side-to-side choledochoduodenostomy for a common bile duct (cbd) stone in 1983, and who presented with fever and right lower chest pain. a hepatic abscess was diagnosed; after it was drained, percutaneous transhepatic biliary drainage was performed. bacteriological studies revealed the presence of bacteroides fragilis and streptococcus intermedius in th ... | 2000 | 10982620 |
| thrombolytic therapy in patients with portal vein thrombosis: case report and review of the literature. | a 29-year-old male patient with crohn's disease of the terminal ileum and previous abdominal surgery was admitted because of severe abdominal pain and signs of bacterial sepsis. the diagnosis of portal vein thrombosis and multiple liver abscesses due to streptococcus intermedius septicaemia was made and antibiotic therapy was instituted immediately. as high-dose heparin therapy was ineffective, urokinase was administered intravenously over a total of 7 days. within 2 days, the patient's symptoms ... | 2000 | 11057461 |
| identification of the anginosus group within the genus streptococcus using polymerase chain reaction. | the aim of this study was to establish an identification method for the anginosus group within the genus streptococcus by polymerase chain reaction (pcr). using a primer pair based on the group-specific sequences of penicillin-binding protein 2b (pbp2b) gene, a 275-bp fragment was amplified from each species in the group but no size-matched products were obtained in other streptococci. further identification in the species or subspecies level was possible by a multiplex pcr with primers for the ... | 2004 | 15043873 |
| humoral immunity host factors in subjects with failing or successful titanium dental implants. | treatment with titanium dental implants is in general successful. however, an unknown number of implants do not integrate and are removed either by exfoliation or at the time of second stage surgery. it would be of importance to identify subjects at risk and predict early implant failure. | 2000 | 11140553 |
| characterization of tn916s, a tn916-like element containing the tetracycline resistance determinant tet(s). | we have characterized a transferable tetracycline resistance (tcr) element from a streptococcus intermedius isolate. the gene responsible for this resistance was identified by pcr and southern hybridization as tet(s). furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to tn916. this element has been designated tn916s. | 2004 | 15205444 |
| mannosidase production by viridans group streptococci. | the production of mannosidase activity by all currently recognized species of human viridans group streptococci was determined using an assay in which bacterial growth was dependent on the degradation of the high-mannose-type glycans of rnase b and subsequent utilization of released mannose. rnase b is an excellent substrate for the demonstration of mannosidase activity since it is a glycoprotein with a single glycosylation site which is occupied by high-mannose-type glycoforms containing five t ... | 2001 | 11230417 |