| microbiological and serological investigations of oral lesions in papillon-lefèvre syndrome. | microbiological and serological (enzyme linked immunosorbent assay) investigations were carried out, including karyotyping, on two asian children with papillon-lefèvre syndrome. in case 1, a girl aged four years, the most prevalent putative periodontopathogens were eikenella corrodens, fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia (deciduous dentition) and bacteroides gracilis, e corrodens and f nucleatum (permanent dentition). in case 2, a boy aged nine years, they we ... | 1996 | 8675741 |
| in vitro activities of trovafloxacin against 557 strains of anaerobic bacteria. | the antimicrobial activity of trovafloxacin for 557 strains of anaerobic bacteria was determined by the national committee for clinical laboratory standards-approved wadsworth agar dilution technique. the species tested included bacteroides fragilis (n = 91), other members of the b. fragilis group (n = 130), campylobacter gracilis (n = 15), other bacteroides spp. (n = 16), prevotella spp. (n = 49), porphyromonas spp. (n = 15), fusobacterium spp. (n = 62), bilophila wadsworthia (n = 24), sutterel ... | 1996 | 8878617 |
| tubo-ovarian abscess caused by multidrug resistant bacteroides gracilis. | bacteroides gracilis infections are very rare and have always been reported to have a polymicrobial etiology. the majority of these infections occur in the head and neck areas, the pleuropulmonary system, and the abdominal cavity. we report a case of tubo-ovarian abscess caused by b. gracilis. a literature search revealed no previous reports. our patient, a 29-year-old woman, experienced fever and lower abdominal pain caused by a tubo-ovarian abscess. her treatment consisted of surgical drainage ... | 1997 | 9216171 |
| recently described clinically important anaerobic bacteria: taxonomic aspects and update. | a new method of identifying bacteria, phylogenetic 16s rrna sequencing, has led to major reorganizations among most genera of anaerobic bacteria. the pigmented prevotella species now comprise seven species including p. nigrescens and p. tannerae; p. intermedia/p. nigrescens-like organisms await inclusion. the former mitsuokella dentalis and hallella seregens were transferred to prevotella as one species, p. dentalis. p. enoeca is a new nonpigmenting prevotella. the genus porphyromonas currently ... | 1997 | 9310640 |
| recently described clinically important anaerobic bacteria: medical aspects. | there is still inadequate information on the role of certain newly described or reclassified anaerobes in disease processes, on their normal sites of carriage, and on their antimicrobial susceptibilities. herein, we summarize this information (most of the literature reviewed is from the past 5 years, but a few of the articles are approximately 10 years old). porphyromonas species had seemed to be relatively nonpathogenic, but recent work indicates that this belief is incorrect. p. gingivalis, p ... | 1997 | 9310641 |
| dental implant infections. | dental implants provide a restorative tool to support crowns, bridge abutments, and removable dentures. osseointegrated implants are titanium posts that are surgically implanted in alveolar bone. a tight immobile bond (osseointegration) forms between bone and titanium, and prosthetic and restorative fixtures are attached to the implants. titanium implants differ from natural teeth, which may make them more susceptible to mechanical stress. a small proportion of implants are not successful and ma ... | 1997 | 9310682 |
| sources and antimicrobial susceptibilities of campylobacter gracilis and sutterella wadsworthensis. | | 1997 | 9310700 |
| evaluation of root canal bacteria and their antimicrobial susceptibility in teeth with necrotic pulp. | this study aimed to evaluate the microbiota of necrotic pulp in teeth without carious lesions where the crown and root were intact and to test the sensitivity of this microbiota to antibiotics in order to improve treatment. the necrotic pulp was sampled from 26 single-rooted teeth in intact pulp chambers. a total of 84 strains were isolated. the number of species isolated per tooth varied from 2 to 8, with a strong component (81%) of anaerobic bacteria. the most commonly represented species were ... | 1997 | 9467386 |
| microbiota of health, gingivitis, and initial periodontitis. | this study compared the subgingival microbiota in periodontal health, gingivitis and initial periodontitis using predominant culture and a dna probe, checkerboard hybridization method. 56 healthy adult subjects with minimal periodontal attachment loss were clinically monitored at 3-month intervals for 12 months. more sites demonstrated small increments of attachment loss than attachment gain over the monitoring period. sites, from 17 subjects, showing > or = 1.5 mm periodontal attachment loss du ... | 1998 | 9495607 |
| microbial complexes in subgingival plaque. | it has been recognized for some time that bacterial species exist in complexes in subgingival plaque. the purpose of the present investigation was to attempt to define such communities using data from large numbers of plaque samples and different clustering and ordination techniques. subgingival plaque samples were taken from the mesial aspect of each tooth in 185 subjects (mean age 51 +/- 16 years) with (n = 160) or without (n = 25) periodontitis. the presence and levels of 40 subgingival taxa ... | 1998 | 9495612 |
| subgingival microflora associated with nifedipine-induced gingival overgrowth. | the purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (go). age was inversely associated with the go. plaque index and bleeding index showed a significant association with go, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of go. the gingival inflammation as e ... | 1998 | 9660335 |
| activities of gemifloxacin (sb 265805, lb20304) compared to those of other oral antimicrobial agents against unusual anaerobes. | the activities of gemifloxacin (sb 265805, lb20304) and comparator agents were determined by an agar dilution method against 419 clinical strains of less-commonly identified species of anaerobes. gemifloxacin was generally more active than trovafloxacin against gram-positive strains by one to two dilutions. peptostreptococci (peptostreptococcus asaccharolyticus, peptostreptococcus magnus, peptostreptococcus micros, and peptostreptococcus prevotii) and porphyromonas spp. (porphyromonas asaccharol ... | 1999 | 10543754 |
| activities of telithromycin (hmr 3647, ru 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and other antimicrobial agents against unusual anaerobes. | the comparative activity of telithromycin (hmr 3647) against 419 human anaerobic isolates was determined by the agar dilution method. at concentrations of </=0.5 microgram/ml, telithromycin was active against actinomyces israelii, actinomyces odontolyticus, bacteroides tectum, bacteroides ureolyticus, bacteroides gracilis (now campylobacter gracilis), porphyromonas spp. (including porphyromonas gingivalis and porphyromonas macacae), prevotella intermedia, prevotella heparinolytica, and almost al ... | 1999 | 10543769 |
| profile of subgingival microbiota in children with primary dentition. | eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the aim of the study was to investigate the composition of the subgingival microbiota of primary incisors, canines and molars in 40 systemically healthy children aged 4-5 yr, chosen randomly. subgingival plaque samples were taken from the mesiobuccal sites of primary incisors (61, 81), canines (53, 73) and molars (64, 84). the samples were cultured for bacterial isolat ... | 2000 | 10791707 |
| microbiological parameters associated with il-1 gene polymorphisms in periodontitis patients. | polymorphisms in the cluster of il-1 genes have been significantly associated with the severity of adult periodontitis. the purpose of this study was to compare microbiological parameters in il-1 genotype negative and positive adult subjects with a range of periodontitis severities. | 2000 | 11073323 |
| comparative in vitro activities of abt-773 against 362 clinical isolates of anaerobic bacteria. | the activity of abt-773, a novel ketolide antibiotic, against clinical isolates of anaerobic bacteria was determined and compared to the activities of other antimicrobial agents. mics at which 90% of isolates were inhibited (mic(90)s) were </=0.06 microg/ml for actinomyces spp., clostridium perfringens, peptostreptococcus spp., propionibacterium spp., and porphyromonas spp. the mic(50)s and mic(90)s were </=0.06 and >32 microg/ml, respectively, for eubacterium spp., lactobacillus spp., clostridi ... | 2001 | 11120995 |
| profile of subgingival microbiota in children with mixed dentition. | a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ... | 2000 | 11155173 |
| assessment of periradicular microbiota by dna-dna hybridization. | in the present study the "checkerboard" dna-dna hybridization technique was used to identify bacteria in periapical endodontic lesions of asymptomatic teeth. thirty-four patients with root-filled teeth and apical periodontitis were divided into two groups, each containing 17 patients. in group 1, a marginal incision was performed during surgery to expose the lesion, and in group 2, a submarginal incision was applied. the gingiva and mucosa were swabbed with an 0.2% chlorhexidine gluconate soluti ... | 2000 | 11202881 |
| campylobacter hominis sp. nov., from the human gastrointestinal tract. | sequences of 16s rdna of a novel campylobacter from faeces of healthy humans were previously shown to originate from a new taxon, 'candidatus campylobacter hominis', which could not be cultured. since phylogenetic analysis suggested that anaerobic conditions might be required for growth, an isolation strategy was developed employing initial non-selective membrane filtration onto fastidious anaerobe agar. campylobacters were then isolated from the resulting mixed microbial flora by a dilution str ... | 2001 | 11321111 |
| antimicrobial activity of silver nitrate against periodontal pathogens. | metal ions were evaluated as potential antimicrobial agents suitable for local delivery in the oral cavity for the treatment of periodontitis. silver nitrate, copper chloride, and zinc chloride were tested for antimicrobial activity in in vitro killing assays conducted in phosphate buffered saline with a series of oral bacteria including gram-negative periodontal pathogens and gram-positive streptococci. copper and zinc salts failed to exhibit strong and consistent activity against periodontal p ... | 2001 | 11327077 |
| comparative in vitro activity of ertapenem and 11 other antimicrobial agents against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections. | we studied the comparative in vitro activity of ertapenem, a new carbapenem, against 240 aerobic and 180 anaerobic recent clinical bite isolates using an agar dilution method and an inoculum of 10(4) cfu/spot for aerobes and 10(5) cfu/spot for anaerobes. ertapenem inhibited 410/420 (98%) of the isolates tested at < or = 4 mg/l with only 4/5 campylobacter gracilis and 1/3 campylobacter rectus strains requiring . or = 16 mg/l for inhibition. ertapenem was only moderately active (mic 8 mg/l) agains ... | 2001 | 11679553 |
| stress and the periodontal diseases: effects of catecholamines on the growth of periodontal bacteria in vitro. | microorganisms possess the ability to recognize hormones within the host and utilize them to adapt to their surroundings. noradrenaline and adrenaline, which are released during human stress responses, may act as environmental cues to alter the growth of individual organisms within subgingival biofilms. the aims of this study were to modify, for anaerobic culture, existing methodology used in determining microorganism catecholamine responses and to investigate the growth responses to noradrenali ... | 2002 | 12354211 |
| campylobacter gracilis and campylobacter rectus in primary endodontic infections. | a species-specific nested polymerase chain reaction (pcr) assay was used to investigate the occurrence of campylobacter gracilis and c. rectus in primary root canal infections. | 2003 | 12657143 |
| [evaluation of anaerobic flora in lung neoplasms]. | purpose of this study was to analyse the kind and frequency of anaerobic bacteria in the lower respiratory tract as well as susceptibility of the bacteria to antibiotics. material from 35 patients with lung tumour derived from tumour and post-tumoural area sample. collected sample was cultivated in anaerobic and aerobic conditions. anaerobic bacteria were found in 23 (66%) samples. totally there were 44 isolated of anaerobic bacteria strains. the most common g-negative strains belonged to genus ... | 2003 | 12959024 |
| a 16s rdna-based nested pcr protocol to detect campylobacter gracilis in oral infections. | the aim of this study was to describe a 16s rdna-based nested polymerase chain reaction (npcr) assay to investigate the occurrence of campylobacter gracilis in oral infections. samples were collected from ten infected root canals, ten cases of acute periradicular abscesses and eight cases of adult marginal periodontitis. dna extracted from the samples was initially amplified using universal 16s rdna primers. a second round of amplification used the first pcr products to detect c. gracilis using ... | 2003 | 14569356 |
| coaggregation profiles of the microflora from root surface caries lesions. | bacterial coaggregation reactions between different species and the auto aggregation of the same species are associated with the initiation and development of dental plaque and biofilms. as no such data is available on isolates from root caries lesions, we evaluated, by a visual, semi-quantitative scoring system and a spectrophotometric, quantitative assay, the coaggregation of 22 different wild-type microbial species comprising ten bacterial genera and a single candida spp. the quantitative coa ... | 2005 | 15598414 |
| impact of sample storage on detection of periodontal bacteria. | information on the impact of sample storage prior to analysis by dna methods is limited. the aim of this study was to investigate the effect of subgingival sample storage on bacterial detection and enumeration. | 2005 | 15720575 |
| subgingival microflora in smokers with early onset periodontitis. | cigarette smoking is a potent risk factor which has recently been associated with periodontal disease progression. the objective of this study was to detect the microbial profile of early onset periodontitis in smokers and compare it to that of non-smokers. the study population consisted of 50 systemically healthy individuals aged 25 to 38 years, exhibiting early onset periodontitis. 25 patients were smokers (> 20 cigarettes/day) and 25 non-smokers. two pooled bacterial samples comprised of four ... | 1997 | 16887581 |
| taxonomy--general comments and update on taxonomy of clostridia and anaerobic cocci. | since such things as sites of normal carriage, type and severity of infections produced, and antimicrobial susceptibility patterns may vary according to the particular species involved, accurate taxonomy for differentiation of species is important. for example, reclassification of the 'bacteroides gracilis group' revealed that sutterella wadsworthensis is actually responsible for the antimicrobial resistance seen in that group. with clostridia and anaerobic cocci, as with other taxa, there have ... | 2002 | 16887670 |
| a pcr-dgge method for detection and identification of campylobacter, helicobacter, arcobacter and related epsilobacteria and its application to saliva samples from humans and domestic pets. | to develop a pcr-denaturing gradient gel electrophoresis (pcr-dgge) method for the detection and identification of campylobacter, helicobacter and arcobacter species (epsilobacteria) in clinical samples and evaluate its efficacy on saliva samples from humans and domestic pets. | 2007 | 17916160 |
| evaluation of the microbiota of primary endodontic infections using checkerboard dna-dna hybridization. | the aim of this study was to evaluate the composition of the microbiota of primary endodontic infections in 111 selected cases of single-rooted teeth with necrotic pulp. | 2007 | 17949342 |
| microbiological evaluation of primary endodontic infections in teeth with and without sinus tract. | to examine the microbiological status of primary endodontic infections in teeth with and without a sinus tract. | 2008 | 18422583 |
| a microbiological profile of symptomatic teeth with primary endodontic infections. | the aim of this study was to evaluate the composition of the microbiota of primary endodontic infections associated with symptomatic teeth. samples were collected by means of a #15 h-type file and 2 sterile paper points from 60 symptomatic (n = 30) or asymptomatic (n = 30) single-rooted teeth with necrotic pulp. the presence of 40 bacterial species was determined by the checkerboard dna-dna hybridization method. the species found in higher counts (x10(5)) in symptomatic cases were fusobacterium ... | 2008 | 18436031 |
| similarities in the subgingival microbiota assessed by a curet sampling method at sites with chronic periodontitis. | the goal of this study was to determine whether site-specific differences in the subgingival microbiota could be detected by the checkerboard method in subjects with periodontitis. | 2008 | 19053919 |
| molecular analysis of persistent periradicular lesions and root ends reveals a diverse microbial profile. | the microbial etiology of periradicular lesions is recognized; however, the bacterial profile of these lesions is not well elucidated. the purpose of this study was to determine the frequency of bacterial colonization in these lesions and to characterize the bacterial community present in root ends and periradicular lesions. | 2009 | 19567313 |
| microbiological profile of untreated subjects with localized aggressive periodontitis. | the microbial profile of localized aggressive periodontitis (lagp) has not yet been determined. therefore, the aim of this study was to evaluate the subgingival microbial composition of lagp. | 2009 | 19637996 |
| microflora associated with successful and failed orthodontic mini-implants. | mini-implants are used for orthodontic bone anchorage. the reasons for a potential instability or loss of the mini-implants during treatment are multiple. among other factors, colonization of implants with pathogenic bacteria is discussed. therefore, the microflora associated with successful and failed mini-implants has been screened. | 2009 | 19719743 |
| comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. | this study compared the subgingival microbiota of subjects with refractory periodontitis (rp) to those in subjects with treatable periodontitis (grs = good responders) or periodontal health (ph) using the human oral microbe identification microarray (homim). | 2009 | 19722792 |
| [bacteria isolated from surgical infections and their susceptibility to antimicrobial agents--special reference to bacteria isolated between april 2007 and march 2008]. | bacteria isolated from infections in abdominal surgery during the period from april 2007 to march 2008 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 707 strains including 24 strains of candida spp. were isolated from 181 (79.0%) of 229 patients with surgical infections. three hundred and ninety-five strains were isolated from primary infections, and 288 strains were isolated from postoperative infections. from primary infections, anae ... | 2009 | 19860320 |
| subgingival microbial profiles of smokers with periodontitis. | the subgingival microbiome is largely uncultivated, and therefore, cultivation-based and targeted molecular approaches have limited value in examining the effect of smoking on this community. we tested the hypothesis that the subgingival biofilm is compositionally different in current and never-smokers by using an open-ended molecular approach for bacterial identification. subgingival plaque from deep sites of current and never-smokers matched for disease was analyzed by 16s sequencing. smokers ... | 2010 | 20739702 |
| osteoradionecrosis contains a wide variety of cultivable and non-cultivable bacteria. | direct microscopy, anaerobic culture and dna-dna hybridization have previously demonstrated an association between microorganisms and osteoradionecrosis (orn). the purpose of our study was to use culture independent molecular techniques to detect bacteria in necrotic bone lesions of the mandible after radiation therapy. | 2010 | 21523230 |
| cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram. | sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ... | 2010 | 3116451 |
| gut hormones in fetal distress. | | 1999 | 91067 |
| hormonal control of delayed development in macrotus waterhousii. ii. radioimmunoassay of plasma estrone and estradiol 17-beta during pregnancy. | | 2005 | 1169184 |
| [severity indexes and prognosis in intensive care. their application in diabetic hyperosmolar coma]. | | 2006 | 1635413 |
| deficiency of eosinophil peroxidase detected by automated cytochemistry. | | 2011 | 3122494 |
| oesophageal pain exacerbated by propranolol. | | 2011 | 3113570 |
| weber-christian panniculitis. | two cases of weber-christian panniculitis with onset at 7 months and 3 years 6 months are described. both show evidence of disturbances in immune mechanisms. the family of the first case has a high prevalence of coeliac disease, and the mother of the first patient also suffers from alopecia areata and dermatitis herpetiformis. | 2013 | 3592792 |
| the effects of diethylstilboestrol on obesity in mice. | | 2016 | 4760785 |
| radiology notes. case 1. eosinophilic granuloma of the spine. | | 2013 | 3871906 |
| anion exchange chromatographic separation of inositol phosphates and their quantification by gas chromatography. | the direct measurement of mass of inositol trisphosphate from biologic samples is described. separation of inositol monophosphate, bisphosphate, trisphosphate, and inositol tetrakisphosphate was achieved using anion exchange chromatography with a sodium sulfate gradient. in addition, separation of the isomers of each inositol phosphate was performed using hplc procedures. the individual inositol phosphate fractions were subsequently dephosphorylated and desalted. the myo-inositol from each fract ... | 1998 | 2653097 |
| fatal leishmaniasis in renal-transport patient. | | 1999 | 88649 |
| not for specialists only--caring for patients with spinal cord injuries. | | 2002 | 2586900 |
| [bronchopneumopathies due to cereals in grain silos workers: etiological and pathogenetical aspects]. | | 2005 | 1226180 |
| cancer risks due to occupational exposure to formaldehyde: results of a multi-site case-control study in montreal. | a case-control study was undertaken in montreal to investigate the possible associations between occupational exposures and cancers of the following sites: oesophagus, stomach, colo-rectum, liver, pancreas, lung, prostate, bladder, kidney, melanoma and lymphoid tissue. in total, 3,726 cancer patients and 533 population controls were interviewed to obtain detailed lifetime job histories and information on potential confounders. each job history was translated into a history of occupational exposu ... | 2009 | 2744897 |
| layer thickness in rotational panoramic radiography: some specific aspects. | it is customary to define the thickness of the image layer in rotational panoramic radiography along the central ray of the x-ray beam. this results in calculated values which overestimate its thickness, especially in regions where the central ray deviates markedly from orthogonality. a supplementary definition is proposed which considers layer thickness in a direction perpendicular to the central plane of the image layer. this provides values which may be more easily related to the thickness of ... | 2009 | 2637877 |
| recurrence risk of neonatal hyperbilirubinemia in siblings. | the recurrence of neonatal hyperbilirubinemia (nhb) in full siblings was studied in 3301 live infants born between 1966 and 1986 to 1669 male us army veterans who were part of a nationwide health study. the study population included 580 sibships with one infant, 679 with two, and 410 with three or more. hospital of birth medical records were abstracted on these children. neonatal hyperbilirubinemia was defined as present if the recorded peak bilirubin level was greater than 205 mumol/l in the ab ... | 2010 | 3177302 |
| recurrence risk of neonatal hyperbilirubinemia in siblings. | the recurrence of neonatal hyperbilirubinemia (nhb) in full siblings was studied in 3301 live infants born between 1966 and 1986 to 1669 male us army veterans who were part of a nationwide health study. the study population included 580 sibships with one infant, 679 with two, and 410 with three or more. hospital of birth medical records were abstracted on these children. neonatal hyperbilirubinemia was defined as present if the recorded peak bilirubin level was greater than 205 mumol/l in the ab ... | 2010 | 3177302 |
| nutritional assessment with body composition measurements. | the measurement of body composition by multiple isotope dilution provides an accurate and precise measure of both the nutritional state and the response to nutritional support. a multiple isotope dilution technique has been developed that permits measurement of the three major components of body composition: body fat, extracellular mass (ecm), and body cell mass (bcm). normal body composition was defined by data obtained in 25 healthy volunteers. malnutrition is characterized by a loss of bcm an ... | 2010 | 3118068 |
| differentiation of exercise-induced metabolic responses during selective beta 1- and beta 2-antagonism. | the effect of beta 1- or beta 2-antagonism on the plasma levels of glucose, lactate, triglycerides, and free fatty acids was studied in seventeen normal male volunteers. all subjects performed three graded and uninterrupted exercise tests until exhaustion. prior to each exercise test they received in a randomized order during three consecutive days either placebo or a predominant beta 1-blocker (atenolol, 50 mg once per day) or a predominant beta 2-blocker (ici 118,551, 20 mg t.i.d.), according ... | 2010 | 3010028 |
| [a case of hepatocellular carcinoma with intratumoral gas formation detected by plain abdominal x-ray film]. | | 2010 | 2846919 |
| [clinical observations on a new preparation with hepatoprotective action]. | | 2011 | 4234340 |
| [development and current status of otolaryngology in moldavia]. | | 2011 | 4245867 |
| [pathogenesis and clinical aspects of struvite urinary calculi]. | | 2012 | 3547359 |
| reduced cerebral blood flow in high altitude climbers. | cerebral blood flow (cbf) was studied by 133xe inhalation dynamic single photon emission computer tomography in 8 members of a climbing expedition to the himalayas. with one exception they had all previously climbed at high altitudes. all stayed above 6,500 m for approximately 3 weeks, and 5 reached the summit of mt. everest. cbf was measured in oslo before, immediately after, and one year after the completion of the expedition. measurements were made at rest and following the injection of 1 g a ... | 2012 | 3495864 |
| levodopa pharmacokinetics and pharmacodynamics in fluctuating parkinsonian patients. | we investigated levodopa intravenous infusion rates, plasma concentrations, and clinical responses in 23 parkinsonian patients with a fluctuating response to the drug. there was a linear relationship between rate of levodopa infusion and plasma concentration when carbidopa was coadministered. minimum-therapeutically effective plasma concentrations of levodopa ranged from 3 to 12 nmol/ml. the duration, but not the magnitude, of clinical response was linearly related to plasma concentrations. the ... | 2013 | 3703280 |
| [bridge design in difficult defect cases]. | | 2013 | 3912758 |
| [treatment of pituitary dwarfism with synthetic anabolic drugs]. | | 2014 | 4646740 |
| pulmonary gas exchange and exercise performance in pulmonary hypertension. | patients with pulmonary hypertension have disordered pulmonary gas exchange and impaired exercise tolerance. the hypoxemia is due to mild ventilation-perfusion (va/q) inequality exaggerated by the presence of a low mixed venous po2 (pvo2) and is accentuated during exercise due to a further fall in pvo2. this in turn may be worsened by vasodilators which increase the degree of va/q inequality. decreased exercise tolerance is due predominantly to cardiac limitation, and thus an improvement in card ... | 2014 | 4042731 |
| [amplitude discriminator with variable levels of discrimination]. | | 2015 | 4649765 |
| bone-conduction threshold sensitivity in relation to mastoid sclerosis. | | 2015 | 4744955 |
| [remote results of treatment of patients with destructive pulmonary tuberculosis]. | | 2015 | 4410737 |
| clinical and laboratory study of a new diuretic agent ("vectren") in pregnancy: a comparison with a diuretic agent in current use ("enduron"). | | 2016 | 4889612 |
| experimental investigation of lsd as a psychotherapeutic adjunct. | | 2016 | 4879643 |
| [eeg-activity patterns in visual information processing: characteristics, variance-analytical deliminiation, discriminance-analytical determination of undispensable variables and scale level]. | 1. in order to determine the variable distributions of 5 activation dependent eeg activity patterns occurring during visual information processing, mean values and standard deviations of the percental quantities of the frequencies 4, 5, ..., 13 hz, 14 to 20 hz and 21 to 30 hz, as well as the mean amplitudes in the frequency bands 3.5 ... 7.4 hz, 7.5 ... 13.4 hz and 13.5 to 30 hz were determined on corresponding to 10 s samples. it could be demonstrated by regression analysis that an interval sca ... | 2004 | 525137 |
| hla antigens in localized granuloma annulare. | hla antigen frequencies were studied in 46 patients with localized granuloma annulare. the results do not support the hypothesis of an association between this condition and insulin-dependent diabetes mellitus. | 1999 | 84475 |
| [diffusion of cefamandole into the prostatic tissue (author's transl)]. | from 21 patients with prostatic adenoma with an average age of 69 years, serum and prostatic tissue concentrations after a single i.v. dose of 2 grams of cefamandole were estimated. the mean serum concentrations 30 minutes after the infusion was completed, were measured with 104.8 and after 60 minutes with 51 microgram/ml. the corresponding concentrations in the prostatic adenoma tissue were after 30 minutes 32.87 and after 60 minutes 17.1 microgram/g. these data are compared with earlier findin ... | 1999 | 84331 |
| [management of hypertensive intracerebral hemorrhage--based on the natural course of the hematoma observed by repeated ct scan (author's transl)]. | | 2000 | 86964 |
| the medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity. | | 2000 | 88711 |
| [intravital detection of the cellular outer perimembrane layers (glycocalyx) using alcian blue. ii. the effect of trypsin processing on glycocalyx sorption of alcian blue]. | | 2001 | 88106 |
| the influence of somatostatin on the absorption of triglycerides in partially gastrectomized subjects. | serum triglyceride levels were measured in 10 partially gastrectomized patients after an oral fat load of 100 g. postprandial triglyceride elevation was completely blocked by somatostatin infusion. this depression cannot be an effect of delayed gastric emptying, because all our patients were billroth-ii operated, but is considered to be due to a direct effect of somatostatin of intestinal absorption. | 2004 | 525216 |
| acute pure sensory paraneoplastic neuropathy with perivascular endoneurial inflammation: ultrastructural study of capillary walls. | we studied a patient with epidermoid carcinoma of the lung (treated surgically 1 year earlier) and an acute symmetric pure sensory neuropathy that regressed almost completely within 1 month. superficial peroneal nerve biopsy 15 days after onset showed evidence of demyelination with perivascular endoneurial inflammation. on ultrastructural examination, lymphocytes were seen passing through endothelial cells of endoneurial capillaries. | 2010 | 3020476 |
| acute pure sensory paraneoplastic neuropathy with perivascular endoneurial inflammation: ultrastructural study of capillary walls. | we studied a patient with epidermoid carcinoma of the lung (treated surgically 1 year earlier) and an acute symmetric pure sensory neuropathy that regressed almost completely within 1 month. superficial peroneal nerve biopsy 15 days after onset showed evidence of demyelination with perivascular endoneurial inflammation. on ultrastructural examination, lymphocytes were seen passing through endothelial cells of endoneurial capillaries. | 2010 | 3020476 |
| fixed drug eruption to mefenamic acid. | | 2010 | 2944503 |
| subcutaneous administration of nifedipine. | contents of a 10 mg nifedipine capsule (0.33 ml) were withdrawn by syringe and administered subcutaneously to a patient with hypertensive urgency due to misinterpretation of a physician's order. the drug apparently had its desired hypotensive effect and no adverse effects were noted. the literature on use of nifedipine in hypertensive urgency is reviewed. subcutaneous administration is not recommended because of a lack of suitable controlled studies and the potential for adverse effects. | 2011 | 3234257 |
| forum on surrogate motherhood: politics and privacy. | | 2011 | 3205041 |
| [visualization of the normal bronchial system by computed tomography]. | imaging of the normal bronchial system by ct was examined in 75 patients while employing different imaging parameters. the main and lobar bronchi could be demonstrated almost without exception in the standard examination of the thorax. segmental bronchi were delineated in an average of 81% of the cases (512 image matrix) or 74% (256 image matrix), respectively. the lowest identification rate was seen in the segmental bronchi of the middle lobe and lingula being 38% (512 image matrix) and 18% (25 ... | 2011 | 3180643 |
| a clinical trial of glycosaminoglycan-peptide complex ('rumalon') in patients with osteoarthritis of the knee. | a clinical trial was undertaken in 50 patients with osteoarthritis of the knee to assess the therapeutic value of glycosaminoglycan-peptide complex in treatment. the first year consisted of a randomized, double-blind, placebo-controlled, parallel-group trial (25 patients in each group), after which all patients received active treatment for a further 2 years. treatment consisted of three 8-week courses in the first year and 2 such courses per year in subsequent years, each consisting of 2 ml int ... | 2012 | 3325230 |
| nutritional supplement use by patients in a rural family practice. | the use of nutritional supplements (vitamins, minerals) has been reported to be as high as 66% for individuals and 54% for households. among medical patients in metropolitan areas, 66% of suburban private patients and 31% of urban clinic patients use supplements. reported here are results of a survey to assess the use of nutritional supplements by rural family medicine patients. a sample of patients (n = 199) in one practice completed a standardized questionnaire, and 54% reported that they had ... | 2013 | 3734277 |
| intracardiac sarcoma diagnosed by left ventricular endomyocardial biopsy. | | 2013 | 3595230 |
| [biosensor development in clinical analysis]. | the use of enzymes immobilized or as markers formed the subject of more than thousand publications in the field of industry or biomedical applications, during the last five years. recently, some authors published works concerning immobilization of total microorganisms for catalytic purposes, others use the enzymatic activity for marking molecules involved in immunological analysis processes. together industrial biotechnology and medical analysis laboratory are interested with the evolution of th ... | 2014 | 3907429 |
| presidential address: adelaide congress. | | 1991 | 269725 |
| muscular dystrophy contrasted with denervation: different mechanisms underlying spontaneous fibrillations. | the data reviewed in this paper indicate that spontaneous fibrillations do not involve a cholinergic mechanism since non-depolarizing anticholinesterase drugs such as mestinon fail to increase spontaneous fibrillations in denervated muscle. fibrillation potentials are related to the changes in electrical properties of the membrane of denervated muscle fibres which lead to the appearance of spontaneous subthreshold depolarizations, sometimes triggering a propagated potential. fibrillations seem t ... | 1998 | 108083 |
| regulation of ribosomal rna synthesis in tetrahymena pyriformis. | ribosomal rna is synthesized at constant rate during most of the cell cycle in heat-shock synchronized populations of tetrahymena pyriformis. early in each macronuclear s-period the rate of synthesis increases abruptly, concomitant with replication of the genes coding for ribosomal rna. the increase is prevented by inhibitors of dna replication, added prior to the s-period. similarly, in cultures synchronized by starvation/refeeding, inhibition of dna replication, at the time when the rdna is re ... | 2000 | 97302 |
| maternal and child health in china. | | 2001 | 98151 |
| biomedical librarians in a patient care setting at the university of missouri-kansas city school of medicine. | the biomedical librarian has been placed in a patient care setting working in the specific environment of a six-year medical school guided by the docent team concept (docent is defined as a clinician-scholar). within this framework the specifically qualified clinical medical librarians function within the docent unit. three dissemination techniques or systems-latch, current references, and latest topics-are discussed. note is made of the clinical medical librarian's role in teaching, demand sear ... | 2015 | 4462680 |
| cases, controls, controversy. | | 2001 | 87974 |
| fitness differences among remnant populations of the endangered sonoran topminnow. | four correlates of fitness were measured in three stocks of the endangered sonoran topminnow, poeciliopsis occidentalis, from arizona. survival, growth, early fecundity, and developmental stability were greatest in laboratory-reared fish from the most heterozygous natural population studied. conversely, all four traits were poorest in fish from a population with no electrophoretically detectable genetic variation. these results emphasize the need for genetic as well as demographic information fo ... | 2009 | 2772650 |
| significance of precordial st-segment depression in inferior acute myocardial infarction as determined by echocardiography. | despite numerous studies, the significance of precordial st-segment depression in inferior wall acute myocardial infarction (ami) remains unclear. no clinical studies have used 2-dimensional (2-d) echocardiography to compare ami location in patients with or without so-called reciprocal st changes. therefore, the clinical, electrocardiographic, echocardiographic and angiographic features of 22 patients with their first transmural inferior ami were prospectively examined. during the first day of a ... | 2014 | 3942081 |
| ralph waldo gerard 1901-1974. | | 2015 | 4618692 |