| novel r-plasmid-mediated beta-lactamase from klebsiella aerogenes. | a novel beta-lactamase with a broad spectrum of activity against penicillins and cephalosporins has been detected in a strain of klebsiella aerogenes. its synthesis is mediated by an r-plasmid of molecular weight 64 x 10(6). | 1977 | 329756 |
| isolation of poly-alpha-l-guluronate lyase from klebsiella aerogenes. | the bacterium klebsiella aerogenes type 25 produces an extracellular alginolyase which has been partly purified. the enzyme is specific for the alpha-l-guluronosyl linkages in whole alginate and fractions therefrom. the end products of its action on polyguluronic acid blocks are mainly the unsaturated di- and tri-saccharides, with a smaller proportion of the homologous tetrasaccharide. some general properties of the enzyme are reported. | 1977 | 332364 |
| experience with amikacin and colistin in an outbreak of infection by resistant klebsiella aerogenes. | | 1977 | 332682 |
| explusion of salibi-clamp from the internal carotied artery in the neck by infection. | a left infraclinoid carotid aneurysm (3 x 2-5 x 2 cm) in a 60-year old woman presented with total ophthalmoplegia and trigeminal symptoms. a staged internal carotied occlusion in the neck was performed using a salibi-clamp. a chronic infectious fistula developed (klebsiella aerogenes). when superficial debridement failed, operative removal of the salibi-clamp was planned seven months after its insertion. the clamp was found subcutaneously without any relation to the internal carotid artery and w ... | 1977 | 333303 |
| affinity chromatography od klebsiella arylsulfatase on tyrosyl-hexamethylenediamine-beta-1,3-glucan and immunoadsorbent. | a simple and convenient method for preparation of a highly purified arylsulfatase (ec 3.1.6.1) from klebsiella aerogenes has been developed. specificity of purification was achieved by using affinity chromatography on a tyrosyl-hexamethylenediamino-beta-1,3-glucan or on a solid phase immunoadsorbent. by using affinity chromatography a homogeneous enzyme was obtained with high yield. it is also proposed that the beads of curdlan type polysaccharide consisting of beta-1,3-glucan can be used as a g ... | 1977 | 334267 |
| bacteriology of abscesses of the central nervous system: a multicentre prospective study. | pus from 46 patients with abscesses of the central nervous system (cns) was examined for bacteria; bacteria were found in all patients. streptococci were isolated from 36 patients and most isolates were streptococcus milleri, lancefield group f, ottens and winkler type o iii. staphylococci were isolated from nine patients, organisms of the bacteroides group from 11, proteus spp from seven, klebsiella aerogenes from one, and haemophilus aphrophilus from one. pure cultures predominated over mixed ... | 1977 | 336141 |
| a comparison of alternate metabolic strategies for the utilization of d-arabinose. | mutants of klebsiella aerogenes w70 that metabolize the uncommon pentose d-arabinose were isolated. these mutants were found to be either constitutive or indicible by d-arabinose for the synthesis of enzymes in the l-fucose pathway. such mutants could then utilize l-fucose isomerase to convert the structurally similar d-arabinose molecule to d-ribulose. d-ribulose is an intermediate and the inducer of an existing ribitol pathway and could thus be metabolized. in those d-arabinose-positive mutant ... | 1977 | 338926 |
| hexokinase and glucose-phosphoenolpyruvate phosphotransferase synthesis in klebsiella aerogenes strains growing in continuous culture. | considerable differences in steady-state hexokinase specific activity were found in 16 n.c.i.b. strains of klebsiella aerogenes grown in identical conditions in glucose-limited chemostats. strains of n.c.i.b. 8258 had no detectable activity, but its glucose-phosphoenolpyruvate phosphotransferase specific activity and that of the other strains were closely similar, and it is concluded that this phosphotransferase activity regulates the overall utilization of glucose, in which hexokinase plays no ... | 1977 | 339911 |
| a hospital epidemic caused by gentamicin-resistant klebsiella aerogenes. | in the 15 months, february 1976 to april 1977, more than 241 patients became colonized with a strain of klebsiella aerogenes, capsular serotype k2, resistant to most antibiotics. urinary tract infection was the most common clinical manifestation but bacteraemia and, occasionally, infections of other sites were encountered. the main reservoir of the epidemic klebsiella was the gut, urine and skin of colonized patients. gut carriage among staff was very uncommon. the most susceptible patients were ... | 1978 | 340580 |
| utilization of arginine by klebsiella aerogenes. | klebsiella aerogenes utilized arginine as the sole source of carbon or nitrogen for growth. arginine was degraded to 2-ketoglutarate and not to succinate, since a citrate synthaseless mutant grows on arginine as the only nitrogen source. when glucose was the energy source, all four nitrogen atoms of arginine were utilized. three of them apparently did not pass through ammonia but were transferred by transamination, since a mutant unable to produce glutamate by glutamate synthase or glutamate deh ... | 1978 | 342501 |
| evaluation and application of an improved bacteriocin typing method for klebsiella aerogenes. | a bacteriocin typing method was evaluated using 200 strains of klebsiella aerogenes, 93% of which fell into 11 distinct types. the typing technique was successfully applied to the monitoring and control of hospital cross-infection. | 1978 | 342545 |
| action of pseudomonas isoamylase on various branched oligo and poly-saccharides. | pseudomonas isoamylase (ec 3.2.1.68) hydrolyzes (1 linked to 6)-alpha-d-glucosidic linkages of amylopectin, glycogen, and various branched dextrins and oligosaccharides. the detailed structural requirements for the substrate are examined qualitatively and quantitatively in this paper, in comparison with the pullulanase of klebsiella aerogenes. as with pullulanase, ps. isoamylase is unable to cleave d-glucosyl stubs from branched saccharides. ps. isoamylase differs from pullulanase in the followi ... | 1978 | 348322 |
| effect of oxygen supply on growth of klebsiella aerogenes in a multistage tower fermentor. | the effect of the rate of oxygen supply on biomass growth, consumption of carbon source formation of metabolic by-products, biomass yeilds referred to c-source and oxygen, respiration rate and the respiratory quotient was studied in a multistage tower fermentor with an interstage backflow, i.e. with a continuous reinoculation of the preceding stages. experiments were done with klebsiella aerogenes ccm 2318 in a synthetic glucose medium with constant glucose concentration in the feed, at ph 7.0. ... | 1978 | 348585 |
| bowls and bacteria. | an episode of nosocomial infection with klebsiella aerogenes in a surgical ward, in which six patients were infected, is described. the cause of the outbreak was identified as being contaminated washing-bowls. it is recommended that each patient should have his own bowl, which should be disinfected after use, dried and stored upside-down. | 1978 | 349076 |
| on the significance of the prosthetic group composition of citrate lyase. | 1. klebsiella aerogenes contains two different acyl carrier proteins, one specific for citrate lyase, the other for fatty acid synthetase. 2. the acyl carrier protein of fatty acid synthetase from k. aerogenes was isolated and compared with the corresponding protein from escherichia coli and with the acyl carrier protein of citrate lyase from k. aerogenes. 3. as judged from prosthetic group compositions as well as amino acid and fingerprint analyses, the acyl carrier proteins of the two fatty ac ... | 1978 | 350581 |
| selective inhibition of klebsiella aerogenes growth on pentoses by pentitols. | selective inhibition of growth by pentitols was observed when klebsiella aerogenes m-7 which could not utilize pentitols was grown on pentoses. d-arabitol inhibited the growth on d-arabinose as a sole carbon source, but had no effect on the growth on l-arabinose, d-xylose, and d-ribose. similarly, l-arabitol inhibited the growth on d-arabinose and l-arabinose, ribitol inhibited the growth on d-arabinose and l-arabinose, and xylitol inhibited the growth on d-xylose. from the following reasons, we ... | 1978 | 350845 |
| [severe klebsiella serogenes infections]. | it is reported on 2 cases of klebsiella-septikaemia with difficult course. germs of the group klebsiella aerogenes could be proved microbiologically. on the basis of the peculiarities of the clinical course the author adopts a definite attitude to the development of the infection, the pathogenesis, to the microbiological proof and to the aimed antimicrobial chemotherapy. the antibiotic treatment was successful in the first case with karbenicillin and gentamycin and in the second case with cephal ... | 1978 | 351992 |
| amino-acid sequence of citrate-lyase acyl-carrier protein from klebsiella aerogenes. | | 1978 | 352686 |
| differentiation of serratia marcescens and serratia liquefaciens by tests for lipase and phospholipase production. | the production of lipase and phospolipase by certain members of the enterobacteriaceae was examined by thin-layer chromatography of resting-cell suspensions incubated with triolein or lecithin. most strains of serratia marcescens produced both enzymes while most strains of serratia liquefaciens exhibited strong lipase but only a minor phospholipase activity. enterobacter spp. (25 strains), klebsiella pneumoniae (20 strains), escherichia coli (15 strains), citrobacter freundii (7 strains) and pro ... | 1978 | 355631 |
| preferential uptake of thymidine by thymineless enterobacteria: its significance in dna labelling. | minimum satisfactory concentrations of thymine and thymidine were determined for the growth of a high thymine-requirng (thy) mutant to escherichia coli strain j5-3. cultures were then grown in the presence of these concentrations of non-radioactive ('cold') pyrimidine together with 5 microci/ml [methyl-3h)thymine, or [methyl-3h)thymidine (specific activities 5 ci/m mole), and the uptake of radioactivity into ice cold trichloroacetic acid insoluble material determined. by far the most efficient l ... | 1977 | 357930 |
| lytic activity of a new cephalosporin, cefuroxime, against gram-negative bacteria. | cefuroxime, a new cephalosporin antibiotic, was inhibitory at low concentrations to several types of gram-negative bacteria. it was considerably more stable than cephaloridine or cephalothin to the beta-lactamases produced by escherichia coli (rp1), klebsiella aerogenes k1 and enterobacter cloacae p99. concentrations of cefuroxime much greater than the minimum inhibitory concentration (mic) were usually necessary to induce lysis of beta-lactamase and non-beta-lactamase producers. in contrast, ce ... | 1978 | 359269 |
| genetic mapping of tyramine oxidase and arylsulfatase genes and their regulation in intergeneric hybrids of enteric bacteria. | the genes for arylsulfatase (atsa) and tyramine oxidase (tyna) have been mapped in klebsiella aerogenes by p1 transduction. they are linked to gdhd and trp in the order atsa-tyna-gdhd-trp-pyrf. complementation analysis using f' episomes from escherichia coli suggested an analogous location of these genes in e. coli, although arylsulfatase activity was not detected in e. coli. p1 phage and f' episomes were used to create intergeneric hybrid strains of enteric bacteria by transfer of the ats and t ... | 1978 | 361719 |
| trypsin peptide patterns of tryptophan synthase beta2 protein among four species of the enterobacteriaceae. | the tryptophan synthase beta 2 protein (ec 4.2.1.20) of escherichia coli, enterobacter aerogenes, serratia marcescens, and erwinia carotovora was purified and compared. two-dimensional total peptide patterns for each of the four beta2 proteins obtained after digestion with trypsin showed that approximately three quarters of the total peptides are common to all four peptides. examination of only arginine-containing peptides showed that approximately half of these peptides are common. from a compa ... | 1978 | 361723 |
| pathophysiologic responses to klebsiella aerogenes bacteria: 24-hour observations. | | 1977 | 364736 |
| the configuration and location of the ribosidic linkage in the prosthetic group of citrate lyase (klebsiella aerogenes). | the structure of the prosthetic group of citrate lyase (klebsiella aerogenes) was studied by nuclear magnetic resonance and mass spectrometry. the spectra at 360 mhz of the nucleoside moiety (2'-ribosyladenosine) show the absence of 2'-hydroxyl proton, thus confirming the 2' position as the site of attachment of the second ribose moiety to the dephospho-coa. this glycosidic linkage is found to be alpha(1" leads to 2') and is identical to that of poly(adp-ribose). studies of permethylation produc ... | 1979 | 368065 |
| bacteriocin typing of serratia marcescens. a simplified system. | the authors describe a simplified system for the detection of bacteriocin production by serratia marcescens with the use of six indicator strains, which include escherichia coli, klebsiella pneumoniae, citrobacter diversus, enterobacter aerogenes (two strains), and serratia rubidaea grown on arabinose minimal medium plates. of the 64 possible bacteriocin types, 11 were observed; 66% of the isolates tested were found to be one of three types. occasionally more than one bacteriocin type was observ ... | 1979 | 371382 |
| cefuroxime therapy for urinary tract infections caused by a multi-resistant, epidemic klebsiella aerogenes. | | 1979 | 372170 |
| respiratory nitrate reductase: its localization in the cytoplasmic membrane of klebsiella aerogenes and bacillus licheniformis. | the sidedness of the respiratory nitrate reductase in the cytoplasmic membrane of bacillus licheniformis and klebsiella aerogenes was studied by indirect immunofluorescence and by lactoperoxidase-catalyzed iodination. it was shown that the two subunits (mr 150000 and 57000, respectively) of nitrate reductase of b. licheniformis are localized on the cytoplasmic side of the membrane, whereas the k. aerogenes enzyme is a transmembrane protein. the different localization of nitrate reductase in the ... | 1979 | 378657 |
| fermentation of 1,2-propanediol with 1,2-ethanediol by some genera of enterobacteriaceae, involving coenzyme b12-dependent diol dehydratase. | klebsiella pneumoniae (aerobacter aerogenes) atcc 8724 was able to grow anaerobically on 1,2-propanediol and 1,2-ethanediol as carbon and energy sources. whole cells of the bacterium grown anaerobically on 1,2-propanediol or on glycerol catalyzed conversion of 1,2-diols and aldehydes to the corresponding acids and alcohols. glucose-grown cells also converted aldehydes, but not 1,2-diols, to acids and alcohols. the presence of activities of coenzyme b(12)-dependent diol dehydratase, alcohol dehyd ... | 1979 | 378959 |
| introduction of bacteriophage lambda into cells of klebsiella aerogenes. | we have shown that a mutation in the cro gene of phage lambda greatly reduces zygotic induction. this observation has allowed us to move this phage on an episome into cells of klebsiella aerogenes where it grows as well as in cells of escherichia coli. this technique should allow the introduction of various derivatives of lambda into any organism which is able to receive deoxyribonucleic acid from e. coli. | 1979 | 378984 |
| acquisition of klebsiella aerogenes by neonates. | the acquisition of klebsiella aerogenes by neonates born in hospital has been studied by sero- and klebecin typing. this organism was more commonly carried in the bowel of breast-fed babies than of bottle-fed babies. only very rarely did babies acquire strains of k. aerogenes from their mothers. k. aerogenes was widely distributed in the ward environment and on the hands of nurses and mothers. some strains were able to spread on the ward. these results are relevant to the control of k. aerogenes ... | 1979 | 379340 |
| the lactose system in klebsiella aerogenes v9a. 6. lactose transport. | | 1979 | 383575 |
| cooperative binding of manganese to citrate lyase from klebsiella aerogenes. | | 1979 | 385345 |
| glucose uptake by klebsiella aerogenes. the role of the glucose-phosphoenolpyruvate phosphotransferase transport system [proceedings]. | | 1979 | 386946 |
| biotypes of klebsiella pneumoniae (sensu lato) and enterobacter aerogenes characterised by differential substrate metabolism: application of the technique. | a biochemical typing method is described for klebsiella pneumoniae (sensu lato) and enterobacter aerogenes. the technique depends on differences in metabolism of five carbon substrates--glycerol, inositol, lactose, glucose, and xylose--at two concentrations. reproducibility is satisfactory and is monitored by the incorporation of control klebsiellae of known biotype. the method has been used for 12 months in the surveillance of urinary tract colonisation in this hospital. gut carriage of klebsie ... | 1979 | 389960 |
| further studies on the sources of klebsiella aerogenes in hospital patients. | we report an investigation into faecal carriage of klebsiella aerogenes and the distribution of this organism in the environment of three wards. in all three wards faecal carriage rates were high (60-70%). the faecal carriage rate increased with antibiotic administration and with length of in-patient stay. k. aerogenes was widely distributed in the ward environment and was found on the hands of nursing staff. clusters of isolations of k. aerogenes of the same serotype were demonstrated indicatin ... | 1979 | 390043 |
| the pathology of human cardiac transplantation: an assessment after 11 years' experience at groote schuur hospital. | over a period of 11 years, commencing in december 1967, 31 cardiac transplants, 10 orthotopic and 21 heterotopic, were performed at groote schuur hospital. two patients with orthotopic transplants have a long survival, 1 for 7 1/2 and 1 for 9 1/2 years, and 1 with a heterotopic transplant for 4 years. eighteen patients have died, and autopsy was performed from 13 to 623 days postoperatively. rejection of the donor heart was found in 61,1% and was the cause of death in 44,4% of cases. infection, ... | 1979 | 390737 |
| purification and properties of klebsiella aerogenes d-arabitol dehydrogenase. | an escherichia coli k12 strain was constructed that synthesized elevated quantities of klebsiella aerogenes d-arabitol dehydrogenase; the enzyme accounted for about 5% of the soluble protein in this strain. some 280 mg of enzyme was purified from 180 g of cell paste. the purified enzyme was active as a monomer of 46,000 mol.wt. the amino acid composition and kinetic constants of the enzyme for d-arabitol and d-mannitol are reported. the apparent km for d-mannitol was more than 3-fold that for d- ... | 1979 | 393250 |
| physiological characteristic and energy balance of klebsiella aerogenes in a multistage tower fermentor. | biomass growth, consumption of carbon and energy source, specific rates of formation of metabolic byproducts, biomass yield referred to the c-source and to oxygen, respiration rate and the value of rq were studied in klebsiella aerogenes ccm 2318 (on a synthetic glucose medium) at different specific growth rates. maintenance coefficients and the total energy balance of the cultivation process were evaluated for a multistage tower fermentor with a defined interstage mixing. the results pointed to ... | 1979 | 393594 |
| energy requirement for maintenance of the transmembrane potassium gradient in klebsiella aerogenes nctc 418: a continuous culture study. | with a glucose-limited culture of klebsiella aerogenes, growing at a fixed dilution rate (0.4 h-1), the specific respiration rate varied progressively as a function of the transmembrane k+ gradient. the latter was varied by changing the input k+ concentration and, under these conditions, the specific respiration rate was linearly related to the electrochemical potential of the k+ gradient. increasing or decreasing the transmembrane k+ gradient in putatively potassium-limited cultures elicited ma ... | 1979 | 395915 |
| influence of the glucose input concentration on the kinetics of metabolic production by klebsiella aerogenes nctc 418: growing in chemostat culture in potassium- or ammonia-limited environments. | with chemostat cultures of klebsiella aerogenes growing at a fixed dilution rate, initially under conditions of glucose-limitation, transition to either potassium-limitation or ammonia-limitation was found not to be a steep step function. a wide range of intermediate steady states could be established in which neither substrate was present in excess of the growth requirement. as the molar ratio of glucose: k+ in the feed medium was progressively increased, the additional glucose carbon was first ... | 1979 | 395916 |
| differential survival of salmonella typhi, escherichia coli, and enterobacter aerogenes on lettuce in the field. | artificial contamination of young lettuce plants with salmonella typhi (st), escherichia coli (ec), and enterobacter aerogenes (ea) in the field in winter and summer resulted in presence of the pathogen and increased density of the two indicator bacteria (ib) in harvested produce. viable counts of the three bacteria/g fresh weight declined at a decreasing rate with increasing time after contamination. the overall pattern of variation of the st/ib ratio was correlated more closely with changes in ... | 1979 | 396737 |
| sampling culturable heterotrophs from microcosms: a statistical analysis. | the contributions of different sources of error in sampling mixed and unmixed bacterial microcosms were evaluated by using analysis of variance. culturable heterotrophic bacteria from a turbid freshwater impoundment were sampled from 9-liter tanks that were unagitated or mixed with magnetic stirrers or pumps and from dilution bottles that were unagitated or agitated with a mechanical shaker. axenic cultures of enterobacter aerogenes were also sampled from manually shaken test tubes. in both agit ... | 1979 | 396887 |
| microcalorimetry studies of energy changes during the growth of klebsiella aerogenes in simple salts/glucose media. 1 establishment of standard conditions. | the shape of the thermogram and the total heat output of aerobically growing cultures of klebsiella aerogenes depend on the nature and state of the inoculum, the composition of the growth medium, aeration in the fermentor and in the calorimeter, and the pump rate of the culture through the microcalorimeter cell. standard conditions of growth and heat measurement have been established which give reproducible thermograms and total heat output. experimental results using different glucose concentra ... | 1979 | 397402 |
| role of environmental factors in uveitis. | as part of a larger study undertaken to determine whether the presence of faecal klebsiella aerogenes was significantly associated with the clinical activity of ankylosing spondylitis, thirteen patients with ankylosing spondylitis and acute non-granulomatous anterior uveitis (angau) were examined. the faeces of eleven of these thirteen patients were found to contain klebsiella aerogenes. this association shows a statistical significance of p less than 0.01, and suggests that klebsiella aerogenes ... | 1979 | 398604 |
| [on the contamination of the citric acid fermentation. i. the contamination by representatives of enterobacteriaceae (author's transl)]. | among the most dangerous bacterial contaminations of the citric acid fermentation is the so-called brown contamination, which is called forth by non pathogenic representatives of enterobacteriaceae like escherichia coli, aerobacter aerogenes, enterobacter cloacae and proteus vulgaris, while other bacteria do not produce the mentioned contamination. there is given a comprehensive characterization of the brown contamination. enterobacteriaceae interrupt the growth of the mycelium of the mold asper ... | 1979 | 398647 |
| r-factor mediated gentamicin resistance in "klebsiella aerogenes". a new problem in nosocomial infection. | | 1979 | 400250 |
| in vitro antimicrobial activity of some cyclic hydroxamic acids and related lactams. | against enterobacter aerogenes 13048, serratia marcescens 13880, klebsiella pneumoniae 10031, pseudomonas aeruginosa 10145, escherichia coli 9723, lactobacillus casei 7469, lactobacillus plantarum 8014, leuconostoc dextranicum 8086, and streptococcus faecalis 8043, the mean minimal inhibitory concentrations of three cyclic hydroxamic acids, 3-amino-3,4-dihydro-1-hydroxycarbostyril, the 6-chloro analog, and the 7-chloro analog, were 0.6, 0.6, and 0.2 micrograms/ml, and those of the corresponding ... | 1978 | 400828 |
| purification and specificity of bacteriolytic enzyme i from hartmannella glebae. | a soil amoeba (hartmannella glebae), when grown in conjunction with enterobacter aerogenes and alcaligenes faecalis, produced two enzymes. enzyme i was purified by gel filtration on sephadex g-100 and chromatography on diethylaminoethyl-cellulose. it is a basic protein. the analysis of the enzymic digest of the cell walls of micrococcus lysodeikticus after reduction and acid hydrolysis showed that the enzyme cleaved the glycosidic bond between acetylmuramic acid and acetylglucosamine of the pept ... | 1977 | 402108 |
| immunochemical comparison of phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase among the enterobacteriaceae. | the bifunctional enzyme of the tryptophan operon, phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase (prai-ingps;ec 4.1.1.48), was characterized by an immunochemical study of six representative members of the enterobacteriaceae: escherichia coli, salmonella typhimurium, enterobacter aerogenes, serratia marcescens, erwinia carotovora, and proteus vulgaris. prai-ingps was purified from e. coli, and antisera were prepared in rabbits. these antisera were utilized in quantitativ ... | 1977 | 403178 |
| immunochemical evidence for the difference between coenzyme-b12-dependent diol dehydratase and glycerol dehydratase. | klebsiella pneumoniae atcc 25955 (formerly named aerobacter aerogenes pzh 572, warsaw), which is known to produce coenzyme-b12-dependent glycerol dehydratase when grown anaerobically in a glycerol medium, formed coenzyme-b12-dependent diol dehydratase in a 1,2-propanediol-containing medium. both the diol dehydratase and the glycerol dehydratase produced by the organism catalyzed the conversion of glycerol, 1,2-propanediol and 1,2-ethanediol to the corresponding aldehydes and underwent concomitan ... | 1977 | 407082 |
| immunization with r mutants of salmonella minnesota. ii. comparison of the protective effect of immunization with lipid a and the re mutant. | the protective effect of active immunization with salmonella minnesota re bacilli or lipid a was assessed in the granulocytopenic rabbit model. animals were immunized with re bacilli, lipid a, or pseudomonas aeruginosa as a nonspecific immunogen. after colonization with one of three enterobacterial strains (two escherichia coli, one enterobacter aerogenes), the immunized rabbits as well as controls given saline injections were made leukopenic with nitrogen mustard and monitored for fever, bacter ... | 1977 | 407161 |
| noxythiolln-resistant organisms in a district general hospital. | twelve strains of pseudomonas aeruginosa, three strains of klebsiella aerogenes, and two strains of escherichia coli were found to be resistant to noxythiolin. some of the pseudomonads were isolated from patients in the same ward, not all of whom were on noxythiolin treatment. the strains from these patients were indistinguishable from each other on phage typing, which suggested cross-contamination. no gram-positive organism was found to be resistant to noxythiolin. noxythiolin should not be use ... | 1977 | 412549 |
| [effect of synthetic iron chelating agensts and of a source of carbohydrate nutrition on catechol biosynthesis by klebsiella aerogenes]. | | 1978 | 416325 |
| respiratory infection in an intensive care unit. | a postmortem bacteriological study of black children in a respiratory intensive care unit showed that pseudomonas aeruginosa was the most common opportunistic pathogen and that it usually complicated a viral infection. in a parallel study of non-debilitated patients in general hospital wards klebsiella aerogenes and escherichia coli were the most frequently isolated organisms. counter-immuno-electrophoresis was used for the identification of pseudomonas-precipitating antibody in serum and trache ... | 1977 | 416503 |
| colonization resistance against potentially pathogenic bacteria in hexaflora-associated gnotobiotic mice. | a study of colonization resistance against potentially pathogenic bacteria (escherichia coli and pseudomonas aeruginosa) was conducted in hexaflora-associated gnotobiotic mice. groups of germfree akr mice were swabbed with five bacterial and a single gastrointestinal yeast species: streptococcus faecalis. lactobacillus brevis. staphylococcus epidermidis, enterobacter aerogenes, bacteroides fragilis var. vulgatus, and torulopsis sp. all species became established in the gut in 8 weeks. later thes ... | 1978 | 417787 |
| accumulation of udp-glucose pyrophosphorylase by axenically grown amoebae of dictyostelium discoideum. | amoebae of the slime mould dictyostelium discoideum ax2 possess only low udp-glucose pyrophosphorylase activity when grown on autoclaved klebsiella aerogenes (approx. 30 units/mg of protein), but accumulate the enzyme to approx. 150-200 units/mg of protein during vegetative growth in axenic medium. the vegetative accumulation of udp-glucose pyrophosphorylase by axenically grown cells is prevented if autoclaved k. aerogenes are included in the axenic medium, suggesting the absence of a specific i ... | 1979 | 426770 |
| studies on the formation of n6-hydroxylysine in cell-free extracts of aerobacter aerogenes 62-1. | we have investigated conditions optimal for the conversion of l-lysine to its n6-hydroxy derivative by partially purified cell-free extracts of aerobacter aerogenes 62-1. the enzyme system was highly specific to l-lysine: the d-isomer and, the n2- or n6-derivatives of lysine, and alpha-amino acids were not hydroxylated. most of the latter compounds had little effect onthe hydroxylation of l-lysine. however, -l-glutamic acid and l-glutamine enhanced the hydroxylation, with half-maximal activation ... | 1979 | 465510 |
| adherence of enterobacteriaceae to human buccal cells. | a preliminary examination has been made of the adherencae isolated from sputa. the radioadherence method was found to correlate well with the conventional light-microscope adherence technique. saturation of buccal-cell binding sites with bacteria occurred when less than 10% of the buccal-cell surface was occupied. the adherence of enterobacter aerogenes to buccal cells was impaired by the prior adherence of bacilli of either the same strain, or of a strain of klebsiella pneumoniae. | 1979 | 469931 |
| storage of microtiter plates for antimicrobial susceptibility tests. | microdilution susceptibility tests are being performed routinely and in increasing numbers in many clinical laboratories. microtiter plates for these assays are usually prepared in large batches and stored frozen until needed. studies were performed to investigate the stability at -20c and at -70c of ampicillin, carbenicillin, ticarcillin, gentamicin, tobramycin, amikacin, chloramphenicol, and cephalothin, using enterobacter aerogenes, proteus mirabilis, proteus vulgaris, escherichia coli, pseud ... | 1979 | 474606 |
| influence of oxygen tension on nitrate reduction by a klebsiella sp. growing in chemostat culture. | at dissolved oxygen tensions of 15 mmhg (2 kpa) and below, nitrate-limited continuous cultures of klebsiella k312 synthesized nitrate reductase (nr) and nitrite reductase (nir) and excreted ammonia. under anaerobic conditions over 60% of the nitrate-nitrogen utilized was excreted as ammonia. in contrast, carbon-limited cultures excreted nitrite at dissolved oxygen tensions of 15 mmhg or below and synthesized nr but not nir. ammonia repressed neither nr nor nir synthesis. these observations indic ... | 1979 | 479838 |
| clinical isolation and characterization of aminoglycoside-resistant small colony variants of enterobacter aerogenes. | small colony variants of enterobacter aerogenes, as well as the parental large colony type, grew in blood drawn for cultures on three separate days from a patient who had received suboptimal gentamicin therapy. minimum inhibitory concentrations of four aminoglycoside antibiotics were eight to more than 16 times higher for small colony variants than for the normal large colony type. small colony variants had defective catalase activity, which may have interfered with oxidative metabolism and amin ... | 1979 | 495639 |
| [septic arthritis and osteomyelitis as a complication of neonatal intensive care (author's transl)]. | in a prematurely born infant of a diabetic mother a purulent arthritis with osteomyelitis of the elbow occurred 18 days after an enterobacter aerogenes-septicemia was proved. enterobacter (aerobacter) aerogenes is a nosocomial gramnegative germ, that is more and more regarded responsible for infection of the newborn in intensive care units. in accordance with the literature recording a high rate functional loss after septic arthritis also our patient suffered from a mobility deficiency in his ri ... | 1979 | 530734 |
| specificity of bacteriolytic enzyme ii from a soil amoeba, hartmannella glebae. | two bacteriolytic enzymes were produced when hartmanella glebae was grown in the presence of both enterobacter aerogenes and alcaligenes faecalis. the identification of enzyme i as n-acetylmuramidase was reported earlier. enzyme ii was purified by gel filtration on a bio-gel a column. a recovery of 68.76% with 72.3-fold purification was obtained. it was found that 5 and 10 mm mgcl2 significantly increased the bacteriolytic activity. it is a basic protein. the cell walls of micrococcus lysodeikti ... | 1979 | 533270 |
| fatty acid compositions of lipid fractions from vegetative cells and mature sorocarps of the cellular slime mold dictyostelium discoideum. | a wild-type strain of dictyostelium discoideum was grown upon aerobacter aerogenes. fatty acid compositions of lipid fractions and of total lipids obtained from vegetative amoebae and mature sorocarps were compared. fatty acids isolated from vegetative cells were found to include large quantities of 17- and 19-carbon cyclopropane fatty acids while straight-chain, saturated fatty acids represented only 10% (w/w) of total fatty acids. these cyclopropane fatty acids appear to be derived from ingest ... | 1977 | 559228 |
| phenotypic modifications in amino acid profiles of cell residues of candida utilis and enterobacter aerogenes. | glucose-limited chemostat cultures of candida utilis were cultivated at various ph levels (3.0-7.5), temperatures (15-37.5 degrees c), dilution rates (0.006-0.42 hr-1), and with one of two nitrogen sources (nh+4 or no-3). enterobacter aerogenes was also cultivated in the chemostat under nitrogen and phosphorus limitations. the amino acid profile of total cell protein is expressed as the content of each amino acid relative to the sum of all amino acids recovered ater acid hydrolysis. cell residue ... | 1977 | 560224 |
| laboratory studies on mecillinam: activity alone and combined with cephradine. | mecillinam (mc) was found to be inhibitory at low concentrations to a wide range of gram-negative bacteria; the sensitivity of such strains could be predicted by using a 10 microgram disk. resistance to mc did not appear to be associated with beta-lactamase-mediated destruction of the antibiotic. ampicillin-resistant strains tended to be less sensitive to mc. mc and cephradine acted synergistically against proteus mirabilis, pr. vulgaris, prov. stuartii and serratia marcescens, and the combinati ... | 1977 | 587708 |
| [9-(adenylyl)alkylcobalamins as inhibitors of adenosylcobalamin-dependent glycerol dehydratase from aerobacter aerogenes]. | the behavior of two coenzyme analogs, [(5-aden-9-yl)methoxyethyl] cob (iii) alamin and [(5-aden-9-yl)pentyl] cob (iii) alamin modified at the nucleoside ligand sugar moiety was studied in the system of adenosyl-cobalamin-dependent glycerol dehydratase from aerobacter aerogenes. it was shown that neither of the analogs possesses coenzyme properties and that both are strong competitive inhibitors for adenosylcobalamin (adocbl). the affinity of the two analogs for the apoenzyme is higher than that ... | 1977 | 588639 |
| microbial conversion of dl-2-amino-delta2-thiazoline-4-carboxylic acid to l-cysteine and l-cystine: screening of microorganisms and identification of products. | microorganisms able to form l-cysteine from dl-2-amino-delta2-thiazoline-4-carboxylic acid (dl-atc), a chemical intermediate in the synthesis of dl-cysteine, were isolated from soil samples and classified as pseudomonas sp., pseudomonas cohaerens, p. desmolytica, and p. ovalis. thirteen l-cysteine-producing bacteria were also found in among 463 stock cultures representing 37 genera. these were achromobacter delmarvae. alcaligenes denitrificans, bacillus brevis, brevibacterium flavum, enterobacte ... | 1977 | 596877 |
| the effects of temperature and growth rate on the proportion of unsaturated fatty acids in bacterial lipids. | the effects of temperature and growth rate on the fatty acid composition of the extractable lipids of four mesophilic and three psychotrophic bacteria were examined. two of the mesophiles (escherichia coli and pseudomonas aeruginosa) increased the proportion of unsaturated fatty acids in their lipids with decreasing temperature over their whole growth temperature range. the other mesophiles (enterobacter aerogenes and lactobacillus casei) increased the proportion of unsaturated fatty acids with ... | 1978 | 624935 |
| comparative in vitro activity of five nitrofurans. | five nitrofurans- nitrofurantoin, nifuratel, nitrofurazone, furazolidone and and sq 18,506--have been tested against 201 microbial strains. escherichia coli, streptococcus faecalis, micrococci and staphylococcus epidermidis were sensitive to all five compounds; furazolidone and sq 18,506 were the most active against these species. klebsiella aerogenes was less sensitive, and proteus spp., providencia stuartii and pseudomonas aeruginosa strains were resistant. nifuratel was inhibitory for some ca ... | 1978 | 657876 |
| method for the simultaneous establishment of many axenic cultures of paramecium. | a method is described for the simultaneous treatment of 42 (or more) stocks of paramecium, and their adaptation to growth in axenic culture. samples of dense cultures of these ciliates growing with enterobacter aerogenes are rendered bacteria-free by migration through 2 sets of tubes containing adaptation medium (peters' salts solution, stigmaterol, vitamins, and autoclaved e. aerogenes). the 2nd set of tubes contains adaptation medium plus antibiotics. bacteria-free samples containing approxima ... | 1978 | 660565 |
| phosphoribosylglycinamide synthetase from aerobacter aerogenes. | | 1978 | 692385 |
| enterobacter aerogenes primary bacteremia in pediatric patients. | enterobacter aerogenes bacteremia associated with the infusion of contaminated admixed intravenous (iv) fluid occurred in seven patients in a pediatric hospital over a five-day period. clinical illness was characterized by spiking fever in all patients. the temporal clustering of cases allowed for rapid recognition of the problem. the primary control measure was the prompt replacement of the iv fluids, although iv antibiotics were also administered. hospital pharmacy practices for admixing iv so ... | 1978 | 704200 |
| a sulphate metabolite of trimethoprim in goats and pigs. | 1. urine from goats and pigs after intravenous administration of [14c]trimethoprim contained an unidentified fraction of 'other water-soluble metabolites'. this fraction accounts for 56% of the administered dose in goat urine and 65% in pig urine. 2. a sulphate metabolite comprising the major part of the latter fraction in both goat and pig urine was isolated by gel filtration and paper chromatography and identified by spectroscopic methods as 2,4-diamino-5-(3,4-dimethoxy-5-sulphooxybenzyl)pyrim ... | 1978 | 726512 |
| [numerical taxonomic studies on enterobacteria of surface-water (author's transl)]. | 435 enterobacterial strains of surface-water were tested in 35 physiological characters and classified numerically by a single-linkage procedure. the relations of similarity are shown in a "vernetzungsdiagramm" (connected graph, fig. 1). tab. 1 specifies the characters of the taxa, which were formed graphically. the following facts are the result of this taxonomic classification: 1. 32% of the escherichia group are kcn-positive. in addition it was found that 60% of the e. coli isolated from the ... | 1978 | 735569 |
| [characteristics of the enterobacteria strains isolated from the urine in urinary tract infections]. | study of biochemical properties of 421 strains of enterobacteria permitted to refer them to the following taxonomic groups of which e. coli constituted 83,4 +/- 3.6%, enterobactercloacae--97 +/- 3.0%, klebsiella 4.0 +/- 2.0%. enterobacter aerogenes, enterobacter hafnia, citrobacter, proteus rettgeri, proteus vulgaris were revealed in individual cases (0.2-1.0%). as a result of serological typing there were revealed 105 serological types of escherichia differing by 55 o-antigen variants, 26 h-ant ... | 1978 | 747014 |
| carbon and nitrogen nutrition of aerobacter aerogenes for valine production. | a number of carbon and nitrogen compounds were tested for their effect on growth of aerobacter aerogenes and valine production. sucrose was found to be the superior carbon source for valine production, while mannose supported maximum cellular growth with very poor yield of valine. urea was found to be the adequate nitrogen source for valine production. supplementation of the synthetic medium with complex nutrients lowered the yield of valine. no direct relationship between the growth of the orga ... | 1978 | 749410 |
| the regulation of carbohydrate metabolism in klebsiella aerogenes nctc 418 organisms, growing in chemostat culture. | klebsiella aerogenes nctc 418 was grown in chemostat cultures (d = 0.17 hr-1; ph 6.8;35 degrees c) that were, successively, carbon-, sulphate-, ammonia-, and phosphate-limited, and which contained as the sole carbon-substrate first glucose, then glycerol, mannitol and lactate. quantitative analyses of carbon-substrate used and products formed allowed carbon balances to be constructed and direct comparisons to be made of the efficiency of substrate utilzation. with all sixteen cultures, carbon re ... | 1975 | 766718 |
| tryptophan operon regulation in interspecific hybrids of enteric bacteria. | we examined tryptophan regulation in merodiploid hybrids in which a plasmid carrying the trp operon of escherichia was introduced into trp mutants of other enteric genera, or in which a plasmid carrying the trpr+ (repressor) gene of e. coli was transfered into fully constitutive trpr mutants of other genera. in these hybrids the trp operon of one species is controlled by the repressor of a different species. similar investigations were possible in transduction hybrids in which either the trp ope ... | 1976 | 770450 |
| derivation and properties of f-prime factors in escherichia coli carrying nitrogen fixation genes from klebsiella pneumoniae. | a his+ nif+ escherichia coli k12, hfr strain (unf43) was constructed by an intergeneric mating between a klebsiella pneumoniae donor strain (hf3) and a his-hfr e. coli strain (sbi824) which transfers his as an early marker. an f-prime nif plasmid, fn39, carrying genes which correspond to the e. coli chromosomal region, metg gnd his shia, but excluding purf and arod, was isolated from unf43. translocation of carbenicillin resistance genes from a p-type r-factor, r68, to fn39 increased the stabili ... | 1976 | 772161 |
| bactericidal activity of bovine neonatal serums for selected coliform bacteria in relation to total protein and immunoglobulin g1 and immunoglobulin m concentrations. | bactericidal activity for a serum-sensitive aerobacter aerogenes strain was associated with antibodies present in immunoglobulin g1 (igg1) and immunoglobulin m (igm), with the greatest activity on a weight basis in igm. activity in immunoglobulin g2 was absent. a total of 118 serums were prepared from blood collected from neonatal calves on farms experiencing unusually high mortality from diarrhea. the serums were allotted to 4 groups on the basis of total serum protein concentrations as follows ... | 1976 | 773223 |
| subunit and chemical composition of citrate lyase from klebsiella pneumoniae. | citrate lyase from klebsiella pneumoniae (previously called klebsiella aerogenes) is shown by amino acid sequencing techniques to contain equimolar amounts of three nonidentical subunits. together with the molecular weight of the enzyme, this finding is interpreted to indicate that there are 6 mol of each of these subunits per mol of native enzyme. a partial amino acid sequence of each of the three subunits is presented. the pure enzyme with a specific activity of 73 units/mg of dry protein has ... | 1976 | 773936 |
| [relation of acetoin and valine in enterobacteriaceae cultures on media with glucose and glycerin]. | the ratio between acetoin and valine produced by the cultures of the family enterobacteriaceae changes upon the addition of glucose and glycerol or their mixture to a defined medium. the experiments were carried out with 12 strains of aerobacter aerogenes and 2 strains of aerobacter cloacae and serratia marcescens. the highest yield of acetoin was found on the medium with glucose (12.5--13.0 g/litre); the maximum accumulation of valine was registered on the medium with glucose and glycerol (1.8- ... | 1975 | 775256 |
| the importance of prolonged incubation for the synthesis of dimethylnitrosamine by enterobacteria. | tests with 140 strains representing escherichia coli, klebsiella aerogenes, k. ozaenae, proteus mirabilis, p. vulgaris, p. rettgeri and p. morganii in a defined medium supplemented with 0-09m dimethylamine (dma) and 0-1m potassium nitrate showed that at least 89% of the 136 strains able to reduce nitrates produced up to 9mm dimethylnitrosamine (dmn) in 70h at 37 degrees c. four nitratase-negative strains produced dmn from dma in the presence of sodium nitrate. prolonged incubation was the most i ... | 1976 | 778390 |
| microbial metabolism of amino alcohols. ethanolamine catabolism mediated by coenzyme b12-dependent ethanolamine ammonia-lyase in escherichia coli and klebsiella aerogenes. | | 1976 | 784902 |
| [characterization by zymograms of r factor-determined beta-lactamases: plasmids of defined and undefined compatibility groups (author's transl)]. | an easy biochemical method is described, discriminating the beta-lacta-mases coded by various r factors. electrophoretic mobility and substrate affinity of beta-lactamases were studied simultaneously for 7 different penicillins and cephalosporins. they are i like r factors assigned into different compatibility groups (n, p, com6, com7, com8, x and com 9), five r factors isolated from piglets faeces and one r factor, ru1, originated from enterobacter aerogenes. three electrophoretic types of beta ... | 1976 | 786104 |
| formation of crystalline deposits by several genera of the family enterobacteriaceae. | several species of bacteria from the family enterobacteriaceae formed crystalline materials containing calcium when grown in a defined culture medium. enterobacter aerogenes, proteus vulgaris, citrobacter freundii, and c. intermedius produced calcium pyrophosphate crystals. edwardsiella tarda and escherichia coli formed calcite iii crystals, whereas proteus mirabilis, klebsiella pneumoniae, providencia stuartii, and serratia marcescens produced hydroxyapatite crystals. several of these bacteria ... | 1976 | 786887 |
| isolation of rough mutants of klebsiella aerogenes and their synthesis of polysaccharides. | two mutants which lacked both capsular and lipopolysaccharide o-antigen polysaccharides were isolated from klebsiella aerogenes serotype 2 by phage selection; these were designated rough mutants. the polysaccharide fractions solubilized by partial acid hydrolysis of the lipopolysaccharide from both the wild type and mutants were chromatographed on sephadex g-50. analysis of the fractions obtained confirmed that the rough mutants lacked the galactan portion of the molecule, which is analogous to ... | 1976 | 789814 |
| oxygen transfer rate, respiration and yields in batch and chemostat cultures of klebsiella aerogenes. | the effect was studied of oxygen supply on the changes in total and specific rate of oxygen consumption by the cells, oxygen transfer rate, saturation concentrations of dissolved oxygen and the yields of batch and continuous cultivations. experiments were done on the microorganism klebsiella aerogenes ccm 2318 growing on synthetic glucose medium. continuous cultivations were carried out at dilution rates of 0.96 and 0.178 h-1. the rate of oxygen transfer was determined by the sulphite method and ... | 1976 | 791773 |
| in vitro growth inhibition of mastitis-causing coliform bacteria by bovine apo-lactoferrin and reversal of inhibition by citrate and high concentrations of apo-lactoferin. | bovine apo-lactoferrin (apo-lf) was added to in vitro cultures of eight strains of coliform bacteria associated with bovine mastitis. as little as 0.02 mg of apo-lf per ml resulted in marked inhibition of growth of all coliforms. growth inhibition was lost if saturated lf or iron plus apo-lf was added to the synthetic medium. the inhibition of growth increased as the concentration of apo-lf increased from 0.02 to 0.2 mg/ml for klebsiella pneumoniae (oardc-a1), klebsiella spp. (k1-21), and aeroba ... | 1976 | 791866 |
| cadmium and zinc sensitivity and tolerance in klebsiella (aerobacter) aerogenes. | the resistance of strains of k. aerogenes ncib 418 'trained' to cd2+ or zn2+ in liquid medium is graded to the training concentration. training to cd2+ increased the sensitivity to zn2+ but training to zn2+ reduced the sensitivity to cd2+. the trained organisms, particularly those trained to cd2+, grow slowly in medium containing the metals and the growth rates after 20 and 200 subcultures were not significantly different. the survival of untrained organisms on cd2+-agar decreased progressively ... | 1976 | 792633 |
| the butanol-soluble proteins of klebsiella aerogenes. | membranes of klebsiella aerogenes were extracted with acid butanol at ph 4.2 and the solubilized proteins were fractionated by precipitation at 0 degrees c and -20 degrees c. the -20 degrees c precipitate was examined by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. several enzyme activities associated with polysaccharide biosynthesis have been identified in the crude -20 degrees c precipitate and an attempt was made to separate the enzymes from other protein. the role of certai ... | 1976 | 792634 |
| the lactose system of klebsiella aerogenes v9a. 5. lac-permease defective mutants of two klebsiella lac plasmids and their apparent reversion to wild type. | | 1976 | 795725 |
| improved large-volume sampler for the collection of bacterial cells from aerosol. | a modified large-volume sampler was demonstrated to be an efficient device for the collection of mono-disperse aerosols of rhodamine b and poly-disperse aerosols of bacterial cells. absolute efficiency for collection of rhodamine b varied from 100% with 5-mum particles to about 70% with 0.5-mum particles. the sampler concentrated the particles from 950 liters of air into a flow of between 1 and 2 ml of collecting fluid per min. spores of bacillus subtilis var. niger were collected at an efficien ... | 1975 | 803820 |
| herd studies on coliform mastitis. | escherichia coli, enterobacter aerogenes, and klebsiella pneumoniae were responsible for 63, 10, and 11 percent, respectively, of 158 coliform organisms recovered from mastitis cases in 8 california herds. the severity and nature of the coliform mastitis problem were found to vary greatly among herds but were characteristic for each of 4 herds studied in detail. | 1975 | 804464 |
| role of the tryptophan group in the action of pullulanase of aerobacter aerogenes. | 1. pullulanase [ec 3.2.1.4.] was inhibited by hg2+, n-bromosuccinimide, 2-hydroxy-5-nitrobenzyl bromide, riboflavine 5'-phosphate, histamine, imidazole, and carbodiimide. 2. the tryptophan groups of the pullulanase were modified by n-bromosuccinimede. it was found that one or two of the 25 tryptophan groups seemed to be important for the activity. 3. studies on difference spectra using various substrates suggested that the tryptophan groups were important for the formation of an enzyme-substrat ... | 1975 | 807566 |
| methyl violet: a selective agent for differentiation of klebsiella pneumoniae from enterobacter aerogenes and other gram-negative organisms. | three selective media for differentiation of klebsiella pneumoniae from enterobacter aerogenes on the basis of colonial morphology were evaluated. using methyl violet 2b as a selective agent, strains of k. pneumoniae isolated from urine, fresh water, and fresh produce were tested against other members of enterobacteriaceae in addition to strains of aeromonas hydrophila and pseudomonas aeruginosa. comparison of colonial morphology showed k. pneumoniae produced larger, smoother colonies than other ... | 1975 | 809008 |
| [vitamin b 12 dependent methionine biosynthesis in pseudomonas aeruginosa]. | among methionineless mutants of pseudomonas aeruginosa strain pao lacking the ability of methylating homocysteine we found two different types: one of them responding to methionine only, the other one to methionine or vitamin b12 alternatively. that means that p. aeruginosa pao as well as other b12-producing bacteria (with one exception: aerobacter aerogenes) use only the b12 pathway (meth) for methionine synthesis. the effect of some cys-auxotrophs equally growing on vitamin b12 as described by ... | 1975 | 809933 |
| susceptibilities of gram-negative bacteria to combinations of antimicrobial agents in vitro. | combinations of either clindamycin or erythromycin with gentamicin, colimycin, or carbenicillin were studied for their antimicrobial effects on clinical isolates of escherichia coli, klebsiella sp., proteus mirabilis, serratia marcescens, enterobacter aerogenes, and pseudomonas aeruginosa. no antagonistic effects of the antibiotic combinations were observed. synergistic effects of the antibiotic combinations were noted against most strains of e. coli tested, especially when either clindamycin or ... | 1975 | 810077 |