| the lipid composition of legionella dumoffii membrane modulates the interaction with galleria mellonella apolipophorin iii. | apolipophorin iii (apolp-iii), an insect homologue of human apolipoprotein e (apoe), is a widely used model protein in studies on protein-lipid interactions, and anti-legionella activity of galleria mellonella apolp-iii has been documented. interestingly, exogenous choline-cultured legionella dumoffii cells are considerably more susceptible to apolp-iii than non-supplemented bacteria. in order to explain these differences, we performed, for the first time, a detailed analysis of l. dumoffii lipi ... | 2016 | 27094351 |
| galleria mellonella apolipophorin iii - an apolipoprotein with anti-legionella pneumophila activity. | the greater wax moth galleria mellonella has been exploited worldwide as an alternative model host for studying pathogenicity and virulence factors of different pathogens, including legionella pneumophila, a causative agent of a severe form of pneumonia called legionnaires' disease. an important role in the insect immune response against invading pathogens is played by apolipophorin iii (apolp-iii), a lipid- and pathogen associated molecular pattern-binding protein able to inhibit growth of some ... | 2014 | 25016052 |