| activities of abt-773 against microaerophilic and fastidious organisms. | abt-773 was tested against 317 fastidious isolates; it inhibited 99% of organisms at a concentration of 4.0 microg/ml. with ampicillin-sulbactam and levofloxacin, only 2 and 6% of these strains, respectively, were resistant at the breakpoint. with clindamycin, penicillin g, and metronidazole, 22, 26, and 58% of the strains, respectively, were resistant. | 2002 | 12121965 |
| biofilm community diversity after exposure to 0·4% stannous fluoride gels. | to test the effect of 0·4% stannous fluoride (snf2 ) glycerine-based gels on specific portions of the bacterial community in both a clinical observational study and in vitro multispecies plaque-derived (mspd) biofilm model. | 2014 | 25263195 |
| the large-scale organization of the bacterial network of ecological co-occurrence interactions. | in their natural environments, microorganisms form complex systems of interactions. understating the structure and organization of bacterial communities is likely to have broad medical and ecological consequences, yet a comprehensive description of the network of environmental interactions is currently lacking. here, we mine co-occurrences in the scientific literature to construct such a network and demonstrate an expected pattern of association between the species' lifestyle and the recorded nu ... | 2010 | 20194113 |
| differences in dna curvature-related sequence periodicity between prokaryotic chromosomes and phages, and relationship to chromosomal prophage content. | periodic spacing of a-tracts (short runs of a or t) with the dna helical period of ~10-11 bp is characteristic of intrinsically bent dna. in eukaryotes, the dna bending is related to chromatin structure and nucleosome positioning. however, the physiological role of strong sequence periodicity detected in many prokaryotic genomes is not clear. | 2012 | 22587570 |
| identification of anaerobic bacteria by bruker biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry with on-plate formic acid preparation. | identification of anaerobic bacteria using phenotypic methods is often time-consuming; methods such as 16s rrna gene sequencing are costly and may not be readily available. we evaluated 253 clinical isolates of anaerobic bacteria using the bruker maldi biotyper (bruker daltonics, billerica, ma) matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) system with a user-supplemented database and an on-plate formic acid-based preparation method and compared resul ... | 2013 | 23254126 |
| potential involvement of campylobacter curvus and haemophilus parainfluenzae in preterm birth. | a woman presented with prelabour premature preterm rupture of membranes and delivered extremely preterm at 26 weeks by caesarean section. histopathology of the placenta indicated moderately severe histological chorioamnionitis with dense infiltration of the chorionic plate by neutrophils. two sets of low and high vaginal swabs were taken from the mother. a set sent for microbiological analysis at the hospital yielded negative results. the second set was analysed employing culture-independent hig ... | 2014 | 25274558 |
| unsupervised statistical discovery of spaced motifs in prokaryotic genomes. | dna sequences contain repetitive motifs which have various functions in the physiology of the organism. a number of methods have been developed for discovery of such sequence motifs with a primary focus on detection of regulatory motifs and particularly transcription factor binding sites. most motif-finding methods apply probabilistic models to detect motifs characterized by unusually high number of copies of the motif in the analyzed sequences. | 2017 | 28056763 |
| comparative genomic analysis of sulfurospirillum cavolei mes reconstructed from the metagenome of an electrosynthetic microbiome. | sulfurospirillum spp. play an important role in sulfur and nitrogen cycling, and contain metabolic versatility that enables reduction of a wide range of electron acceptors, including thiosulfate, tetrathionate, polysulfide, nitrate, and nitrite. here we describe the assembly of a sulfurospirillum genome obtained from the metagenome of an electrosynthetic microbiome. the ubiquity and persistence of this organism in microbial electrosynthesis systems suggest it plays an important role in reactor s ... | 2016 | 26983005 |
| occurrence and characteristics of fastidious campylobacteraceae species in porcine samples. | this study investigated the prevalence and characteristics of campylobacteraceae including a range of fastidious species in porcine samples. over a thirteen month period caecal contents (n=402) and pork carcass swabs (n=401) were collected from three pork abattoirs and pork products (n=399) were purchased at point of sale in the republic of ireland. campylobacteraceae isolates were recovered by enrichment, membrane filtration and incubation in antibiotic free media under a modified atmosphere (3 ... | 2013 | 23474652 |
| epsilonproteobacterial hydroxylamine oxidoreductase (εhao): characterization of a 'missing link' in the multihaem cytochrome c family. | members of the multihaem cytochrome c (mcc) family such as pentahaem cytochrome c nitrite reductase (nrfa) or octahaem hydroxylamine oxidoreductase (hao) are involved in various microbial respiratory electron transport chains. some members of the hao subfamily, here called εhao proteins, have been predicted from the genomes of nitrate/nitrite-ammonifying bacteria that usually lack nrfa. here, εhao proteins from the host-associated epsilonproteobacteria campylobacter fetus and campylobacter curvu ... | 2017 | 28388834 |
| empyema associated with campylobacter curvus infection. | we report the first case of thoracic empyema associated with campylobacter curvus infection. a 65-year-old woman with a history of bronchiectasis presented with acute cough and phlegm. the patient reported dyspnoea and left chest pain accompanied by left pleural effusion, despite treatment with sitafloxacin. curved gram-negative rods, eventually identified as c. curvus using 16s ribosomal rna- and atpa-specific polymerase chain reaction (pcr) and sequencing, were cultured in anaerobic condition ... | 2017 | 28413685 |