| etiology and treatment of childhood peptic ulcer disease in taiwan: a single center 9-year experience. | peptic ulcer disease (pud) in children is relatively rare as compared with adults. this study aimed to assess the etiology, clinical and histological characteristics, and treatment of pud in children. | 2010 | 20123589 |
| gastric cardia adenocarcinoma in taiwanese men: positive associations due to selection bias. | the factors associated with an increase in gastric cardia adenocarcinoma are poorly understood. environmental factors such as helicobacter pylori (h. pylori) infection and diet have been hypothesized to play a role in the recently increased risk of this disease, but additional studies are needed. in conducting studies to establish the relationship between potential risk factors and gastric cardia adenocarcinoma, it is necessary to carefully consider the role of bias. in a recently published stud ... | 2010 | 20333802 |
| in vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against helicobacter pylori isolates in taiwan, 1998-2007. | the minimum inhibitory concentrations (mics) of 330 nonduplicate helicobacter pylori isolates to nemonoxacin, tigecycline, and eight other antimicrobial agents were determined by using the agar dilution method. sequencing the quinolone resistance-determining regions (qrdrs) in the gyra gene of these isolates was also performed. resistance to clarithromycin showed an increasing trend during the ten-year study period and was highest (38%) in 2005. tigecycline had potent in vitro activities against ... | 2010 | 20658256 |
| interleukin-1beta and -10 polymorphisms influence erosive reflux esophagitis and gastritis in taiwanese patients. | helicobacter pylori (h. pylori) infection induces cytokine production and is associated with gastrointestinal diseases. this study examined the relationship of gene polymorphisms, including interleukin (il)-1beta, -10, -8, and tumor necrosis factor-alpha (tnf-alpha), h. pylori infection, and susceptibility to gastrointestinal disorders in taiwanese patients. | 2010 | 20659236 |
| matrix metalloproteinase-3 promoter polymorphisms but not dupa-h. pylori correlate to duodenal ulcers in h. pylori-infected females. | this study investigated if the h. pylori dupa genotype and certain host single nucleotide polymorphisms (snps) of matrix metalloproteinases (mmps) and their inhibitors (timps), including mmp-3, mmp-7, mmp-9, timp-1 and timp-2, might correlate with ulcer risk of h. pylori-infected taiwanese patients. | 2010 | 20707923 |
| e2a-positive gastric malt lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory b-cell-associated mir-223: possible correlation with stage and treatment response. | extranodal marginal-zone lymphoma of mucosa-associated lymphoid tissue of the stomach (gastric malt lymphoma) is derived from memory b cells of the marginal zone. normal memory b cells do not express markers of germinal-center b cells, such as e2a (immunoglobulin enhancer-binding factor e12/e47), b-cell chronic lymphocytic leukemia/lymphoma 6 (bcl6), or activation-induced cytidine deaminase (aid). e2a is a transcription factor that induces somatic hypermutations and blocks plasma cell differenti ... | 2010 | 20802470 |
| seroprevalence of helicobacter pylori infection among schoolchildren and teachers in taiwan. | helicobacter pylori are associated with chronic antral gastritis that is related to duodenal ulcer, gastric ulcer, and probably gastric adenocarcinoma. infection of h. pylori during childhood is considered an important risk factor for gastric carcinoma in adult life. | 2007 | 17493007 |
| gut check: can cost-effectiveness analysis help eliminate gastric cancer in asia? | | 2007 | 17507608 |
| cost-effectiveness analysis between primary and secondary preventive strategies for gastric cancer. | the present study is done to assess the relative cost-effectiveness, optimal initial age, and interscreening interval between primary and secondary prevention strategies for gastric cancer. | 2007 | 17507609 |
| the prevalence and risk factors of reflux esophagitis among adult chinese population in taiwan. | risk factors of reflux esophagitis among chinese in taiwan are at present not clear and the role of helicobacter pylori infection in the development of reflux esophagitis is still controversial. | 2007 | 17881927 |
| precancerous gastric conditions in high helicobacter pylori prevalence areas: comparison between eastern european (lithuanian, latvian) and asian (taiwanese) patients. | the aim of the study was to compare the prevalence and severity of precancerous condition--gastric atrophy and intestinal metaplasia (im) between eastern european (lithuania and latvia) and asian (taiwan) countries in population older than 55 years. | 2007 | 17895638 |
| the peopling of the pacific from a bacterial perspective. | two prehistoric migrations peopled the pacific. one reached new guinea and australia, and a second, more recent, migration extended through melanesia and from there to the polynesian islands. these migrations were accompanied by two distinct populations of the specific human pathogen helicobacter pylori, called hpsahul and hspmaori, respectively. hpsahul split from asian populations of h. pylori 31,000 to 37,000 years ago, in concordance with archaeological history. the hpsahul populations in ne ... | 2009 | 19164753 |
| role of omeprazole dosage and cytochrome p450 2c19 genotype in patients receiving omeprazole-amoxicillin dual therapy for helicobacter pylori eradication. | to determine the factors that may influence helicobacter pylori eradication in patients receiving omeprazole-amoxicillin dual therapy. | 2011 | 21361732 |
| duodenal ulcer disease, gastroduodenal motor function and reflux esophagitis - a cross-sectional survey in a subset of taiwanese patients. | backgroundôçé to investigate the association between the gastric emptying rate and the presence of erosive esophagitis in duodenal ulcer (du) patients among a population with high prevalence of helicobacter pylori infection. methodsôçé cross-sectional survey was performed in a cohort of 60 male patients with either active or healed du, with or without the presence of erosive esophagitis. clinical and social-demographic data, blood level of fasting gastrin, pepsinogen i & i/ii ratio, and scintigr ... | 2011 | 21714832 |
| Male Gender, Hiatus Hernia and Helicobacter Pylori Infection Associated with Asymptomatic Erosive Esophagitis. | Background and Aims: Asymptomatic erosive esophagitis (AEE) is an easily forgotten subgroup of gastroesophageal reflux disease (GERD) due to it's lack of warning symptoms despite having the risk of developing complications such as bleeding, stricture or even esophageal adenocarcinoma. Materials and Methods: A total of 2843 potentially eligible subjects were screened at the health management center of Buddhist Tzu Chi General Hospital. 1002 subjects responded to this survey and gave informed cons ... | 2011 | 21871022 |
| spatial autocorrelation calculations of the nine malignant neoplasms in taiwan in 2005-2009: a gender comparison study. | spatial analytical techniques and models are often used in epidemiology to identify spatial anomalies (hotspots) in disease regions. these analytical approaches can be used to identify not only the location of such hotspots, but also their spatial patterns. we used spatial autocorrelation methodologies, including global moran's i and local getis-ord statistics, to describe and map spatial clusters and areas in which nine malignant neoplasms are situated in taiwan. in addition, we used a logistic ... | 2011 | 22035856 |
| genome, integration, and transduction of a novel temperate phage of helicobacter pylori. | helicobacter pylori is a common human pathogen that has been identified to be carcinogenic. this study isolated the temperate bacteriophage 1961p from the lysate of a clinical strain of h. pylori isolated in taiwan. the bacteriophage has an icosahedral head and a short tail, typical of the podoviridae family. its double-stranded dna genome is 26,836 bp long and has 33 open reading frames. only 9 of the predicted proteins have homologs of known functions, while the remaining 24 are only similar t ... | 2012 | 22696647 |
| screening and treating helicobacter pylori infection for gastric cancer prevention on the population level. | helicobacter pylori infection is the major cause of gastric cancer, and removal of h. pylori infection from a population could theoretically decrease the number of cases by about 89%. however, in real-life settings, few studies have reported the effect of screening and treating this pathogen in population-based programs. this is mainly because of the lack of an adequate infrastructure for delivery of systematic screening services to asymptomatic individuals, the lack of standardization to ensure ... | 2017 | 28087975 |
| consensus on the clinical management, screening-to-treat, and surveillance of helicobacter pylori infection to improve gastric cancer control on a nationwide scale. | previous international consensus statements provided general policies for the management of helicobacter pylori infection. however, there are geographic differences in the prevalence and antimicrobial resistance of h. pylori, and in the availability of medications and endoscopy. thus, nationwide or regional consensus statements are needed to improve control of h. pylori infection and gastric cancer. | 2017 | 28066960 |
| association of vagus nerve severance and decreased risk of subsequent type 2 diabetes in peptic ulcer patients: an asian population cohort study. | vagus nerve may play a role in serum glucose modulation. the complicated peptic ulcer patients (with perforation or/and bleeding) who received surgical procedures with or without vagotomy provided 2 patient populations for studying the impact of vagus nerve integrity. we assessed the risk of developing type 2 diabetes in peptic ulcer patients without and with complications by surgical treatment received in a retrospective population study using the national health insurance database in taiwan.a ... | 2016 | 27930533 |
| metformin and esophageal cancer risk in taiwanese patients with type 2 diabetes mellitus. | this study evaluated whether metformin might reduce esophageal cancer risk. patients with type 2 diabetes mellitus diagnosed during 1999-2005 were recruited from the reimbursement database of taiwan's national health insurance. those newly treated with metformin (n = 288013, "ever users of metformin") or other antidiabetic drugs (n = 16216, "never users of metformin") were followed until december 31, 2011. sensitivity analyses were conducted in a matched-pair sample of 16216 never users and 1621 ... | 2016 | 27861146 |
| concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of helicobacter pylori: a multicentre, open-label, randomised trial. | whether concomitant therapy is superior to bismuth quadruple therapy or 14-day triple therapy for the first-line treatment of helicobacter pylori infection remains poorly understood. we aimed to compare the efficacy and safety of 10-day concomitant therapy, 10-day bismuth quadruple therapy, and 14-day triple therapy in the first-line treatment of h pylori. | 2016 | 27769562 |
| the association of helicobacter pylori eradication with the occurrences of chronic kidney diseases in patients with peptic ulcer diseases. | the association of helicobacter pylori eradication with the occurrence of renal dysfunction in patients with peptic ulcer diseases is still unclear. this study aimed to clarify the relevance of h. pylori eradication to the occurrence of chronic kidney diseases in patients with peptic ulcer diseases. data that were available from 2000-2011 were extracted from the national health insurance research database in taiwan, and all patients with peptic ulcer diseases (n = 208 196) were screened for elig ... | 2016 | 27764171 |
| analysis of patients with helicobacter pylori infection and the subsequent risk of developing osteoporosis after eradication therapy: a nationwide population-based cohort study. | previous studies have reported conflicting results on the association between helicobacter pylori infection and osteoporosis. a few studies have discussed the influence of h. pylori eradication therapy on bone mineral density. | 2016 | 27626940 |
| first-line helicobacter pylori eradication among patients with chronic liver diseases in taiwan. | helicobacter pylori eradication in patients with chronic liver diseases (clds) and liver cirrhosis is seldom reported. this study aimed to assess the efficacy of 7-day standard triple therapy in patients with cld including cirrhosis and to investigate the clinical factors influencing the success of eradication. a total of 592 h. pylori-infected patients, who received 7-day standard first-line triple therapy between january 1, 2014, and december 31, 2014, were recruited. patients were divided int ... | 2016 | 27523452 |
| early eradication has a lower risk of peptic ulcer bleeding in helicobacter pylori-infected chronic kidney disease patients. | end stage renal disease (esrd) contributes to a higher mortality rate in peptic ulcer bleeding (pub) patients. a crucial question is whether early helicobacter pylori (h. pylori) eradication therapy is necessary for h. pylori-infected chronic kidney disease (ckd) patients. to explore whether h. pylori eradication therapy has a lower risk of pub at the pre-esrd stage than at the esrd stage. | 2016 | 27449117 |
| nonbismuth concomitant quadruple therapy for helicobacter pylori eradication in chinese regions: a meta-analysis of randomized controlled trials. | to evaluate the applicability of nonbismuth concomitant quadruple therapy for helicobacter pylori (h. pylori) eradication in chinese regions. | 2016 | 27340362 |
| the clinical significances of irritable bowel syndrome in taiwan. | according to the rome iii definition, irritable bowel syndrome (ibs) has been a biopsychosocial dysfunction. we tried to know whether the ibs clinical manifestations were comparable to other countries. | 2011 | 21443720 |
| prospective survey for the etiology and outcome of peptic ulcer bleeding: a community based study in southern taiwan. | helicobacter pylori infection and drugs are the two major risk factors for peptic ulcer bleeding. the role of these two factors may change with changes in the prevalence of h pylori and use of nsaids. this study aimed to determine the cause, endoscopic features, and outcome of peptic ulcer bleeding in a community hospital in southern taiwan. | 2011 | 21540004 |
| weekly pattern of emergency room admissions for peptic ulcers: a population-based study. | to investigate variations in the incidence of peptic ulcers (pus) in taiwan by day of the week within age subgroups. | 2015 | 25805943 |
| seroprevalence of helicobacter pylori and hepatitis a virus among children in rural central taiwan. | helicobacter pylori and hepatitis a virus (hav) are thought to have similar routes of transmission and epidemiology. this study investigated the seroprevalence of these 2 pathogens among children in rural, central taiwan. serum samples were collected from 856 children between 2010 and 2012 and levels of anti-hav and anti-h. pylori antibodies were measured by elisa. questionnaires were used to investigate possible risk factors. the overall h. pylori and hav infection rates were 6% and 0.8%, respe ... | 2015 | 25866110 |
| association between helicobacter pylori infection and the subsequent risk of end-stage renal disease: a nationwide population-based cohort study. | the association between helicobacter pylori infection and end-stage renal disease (esrd) events remains unknown. we assessed the relationship between h. pylori infection requiring hospital admission and the subsequent risks of esrd. | 2015 | 25644865 |
| statins attenuate helicobacter pylori caga translocation and reduce incidence of gastric cancer: in vitro and population-based case-control studies. | gastric cancer is the second leading cause of cancer-related death worldwide. the correlation of helicobacter pylori and the etiology of gastric cancer was substantially certain. cholesterol-rich microdomains (also called lipid rafts), which provide platforms for signaling, are associated with h. pylori-induced pathogenesis leading to gastric cancer. patients who have been prescribed statins, inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme a (hmg-coa) reductase, have exhibited a reduced risk ... | 2016 | 26730715 |
| helicobacter pylori test-and-treat program can be cost-effective to prevent gastric cancer in taiwanese adults: referred to the nationwide reimbursement database. | helicobacter pylori infection increases the risk of gastric cancer. the study aimed to compare cost-effectiveness ratios of h. pylori test-and-treat programs to prevent gastric cancer in taiwan, referring to the nationwide reimbursement database and expected years of life lost. | 2015 | 25382169 |
| the associations between helicobacter pylori infection, serum vitamin d, and metabolic syndrome: a community-based study. | the associations between helicobacter pylori infection, serum vitamin d level, and metabolic syndrome (ms) are controversial. the present community-based study aimed to investigate the effect of h pylori infection and serum vitamin d deficiency on ms development.individuals from the northeastern region of taiwan were enrolled in a community-based study from march, 2014 to august, 2015. all participants completed a demographic survey and underwent the urea breath test (ubt) to detect h pylori inf ... | 2016 | 27149497 |
| angiotensin ii receptor blocker prevents upper gastrointestinal bleeding in hypertensive patients with chronic kidney disease not on dialysis. | investigate if angiotensin ii receptor blocker (arb) decreases risk of upper gastrointestinal bleeding (ugib) in hypertensive patients with chronic kidney disease (ckd) not on dialysis. | 2015 | 25651030 |
| helicobacter pylori infection is positively associated with metabolic syndrome in taiwanese adults: a cross-sectional study. | helicobacter pylori infection and metabolic syndrome have been reported to be positively associated. however, only a few studies have focused on this issue, and h. pylori serum antigen was used to diagnose infection in most of them. we aimed to investigate the association between metabolic syndrome factors and h. pylori infection, as diagnosed via a (13)c-urea breath test. | 2015 | 25582223 |
| levofloxacin-containing second-line anti-helicobacter pylori eradication in taiwanese real-world practice. | quinolone-containing triple therapy is recommended as an option for non-bismuth containing second-line helicobacter pylori eradication. current available taiwanese reports in the literature used 7-day quinolone-containing triple therapy. as a result, some physicians still prescribe 7-day regimens in real-world practice in taiwan. this study aimed to further assess the appropriateness of 7-day levofloxacin-containing triple therapy as second-line therapy. | 2014 | 25163495 |
| no inverse relationship between helicobacter pylori infection and adult asthma with peptic ulcer disease. | inverse correlation between childhood-onset asthma and human gastric helicobacter pylori (h. pylori) infection exists. to investigate whether adult asthma patients with peptic ulcer disease demonstrated lower rates of h. pylori infection. | 2014 | 24901176 |
| helicobacter pylori infection increases subsequent ischemic stroke risk: a nationwide population-based retrospective cohort study. | the association of helicobacter pylori infection (hp-i) with ischemic stroke (is) incidence has been studied, but conflicting results have been reported. the purpose of this study was to investigate the association between chronic hp-i and the risk of acute is by using data from the taiwan national health insurance research database. | 2014 | 24890556 |
| gastric helicobacter pylori infection associated with risk of diabetes mellitus, but not prediabetes. | the association between helicobacter pylori infection and diabetes was inconsistent in previous studies. moreover, there are no studies on the relationship between h. pylori infection and prediabetes in the literature. the aim of this study is thus to assess the association of helicobacter infection, diagnosed by pathology from gastric biopsy, with diabetes and prediabetes. | 2014 | 24731067 |
| a tool to predict risk for gastric cancer in patients with peptic ulcer disease on the basis of a nationwide cohort. | patients with gastric ulcers have significantly higher risk of gastric cancer, especially within 2 years after diagnosis. we used data from a national database to develop a personalized risk prediction model for patients with peptic ulcer diseases. | 2015 | 25083561 |
| helicobacter pylori infection and the risk of acute coronary syndrome: a nationwide retrospective cohort study. | helicobacter pylori infection (hpi) imposes substantial social costs and is of major etiological importance in peptic ulcer disease, gastric cancer, and accelerated cardiovascular diseases. this study determined the risk of acute coronary syndrome (acs) associated with hpi in a nationwide retrospective cohort study. by using the taiwan national health insurance research database (nhird), we identified patients diagnosed with hpi from 1998 to 2010. in addition, we randomly selected non-hpi contro ... | 2015 | 25063740 |
| lower helicobacter pylori infection rate in chronic kidney disease and end-stage renal disease patients with peptic ulcer disease. | distinguishing the rates of helicobacter pylori infection in chronic kidney disease (ckd) and end-stage renal disease (esrd) patients with peptic ulcer disease (pud) from that in pud patients without ckd is critical. | 2014 | 24907021 |
| increased risk of chronic obstructive pulmonary disease among patients with helicobacter pylori infection: a population-based cohort study. | increasing evidence suggests that helicobacter pylori infection (hpi) may have extragastric manifestations, including the respiratory system. this study investigated the role of hpi in increasing the subsequent risk of chronic obstructive pulmonary disease (copd) in a nationwide population. | 2015 | 26364850 |
| alteration of the tongue manifestation reflects clinical outcomes of peptic ulcer disease. | this study investigated whether the tongue inspection technique in traditional chinese medicine (tcm) can be used as a noninvasive auxiliary diagnostic tool to differentiate the subtypes of peptic ulcer disease (pud) and as an indicator of therapeutic efficacy. | 2012 | 23153037 |
| five-year sequential changes in secondary antibiotic resistance of helicobacter pylori in taiwan. | to determine changes in the antibiotic resistance of helicobacter pylori (h. pylori) in southern taiwan after failure of first-line standard triple therapy. | 2015 | 26457027 |
| helicobacter pylori infection increases insulin resistance and metabolic syndrome in residents younger than 50 years old: a community-based study. | this study aimed to analyze the influence of h. pylori infection on insulin resistance and metabolic syndrome (ms) by multivariate analysis of a community-based cohort study. from january 2013 to february 2014,811 subjects were enrolled in a community-based cohort study from the northeastern region of taiwan. all subjects received a demographic survey and blood tests, including an h. pylori antibody test, liver biochemistry tests, lipid profiles, sugar/insulin levels for homeostatic model assess ... | 2015 | 26020514 |
| comparative in vitro antimicrobial susceptibility and synergistic activity of antimicrobial combinations against helicobacter pylori isolates in taiwan. | antimicrobial resistance is a major determinant of helicobacter pylori treatment failures. we conducted a population-based survey to monitor changing antimicrobial susceptibility of h. pylori isolates in taiwan, with a focus on combinatorial effects of synergism and the influence of acidity. | 2015 | 23036269 |
| the efficacy of second-line anti-helicobacter pylori therapy using an extended 14-day levofloxacin/amoxicillin/proton-pump inhibitor treatment--a pilot study. | large meta-analyses of second-line helicobacter pylori eradication with fluoroquinolone triple therapy have shown that neither 7-day nor 10-day therapy provides 90% or better treatment success. reports describing second-line h. pylori eradication using 14-day fluoroquinolone-containing triple therapy are few. current study aimed to determine the efficacy of a 14-day levofloxacin/amoxicillin/proton-pump inhibitor regimen as second-line therapy and the clinical factors influencing the outcome. | 2012 | 22967121 |
| the primary resistance of helicobacter pylori in taiwan after the national policy to restrict antibiotic consumption and its relation to virulence factors-a nationwide study. | the taiwan government issued a policy to restrict antimicrobial usage since 2001. we aimed to assess the changes in the antibiotic consumption and the primary resistance of h. pylori after this policy and the impact of virulence factors on resistance. | 2015 | 25942450 |
| eradication of helicobacter pylori infection by the probiotic strains lactobacillus johnsonii mh-68 and l. salivarius ssp. salicinius ap-32. | the current therapy for helicobacter pylori infection includes antimicrobial agents and proton pump inhibitors. we have examined the ability of lactobacillus spp. to inhibit h. pylori infection. | 2012 | 23067294 |
| randomized comparison of two non-bismuth-containing second-line rescue therapies for helicobacter pylori. | classical second-line anti-helicobacter pylori includes proton-pump inhibitor, tetracycline, metronidazole, and bismuth salts, but alternative therapies are required owing to the restricted availability of the latter. levofloxacin-containing triple therapy is recommended but is expensive. besides, quinolone resistance in an endemic tuberculosis infection area like taiwan is concerned. the low in vitro antibiotic resistance to amoxicillin and tetracycline in taiwanese h. pylori strains implies th ... | 2012 | 22515360 |
| gemifloxacin can partially overcome quinolone resistance of h. pylori with gyra mutation in taiwan. | the levofloxacin resistance caused by gyra gene mutation is rising rapidly to limit wide application for helicobacter pylori eradication. we investigated whether gemifloxacin has a superior antimicrobial activity to levofloxacin against h. pylori. | 2012 | 22515359 |
| esomeprazole alone compared with esomeprazole plus aspirin for the treatment of aspirin-related peptic ulcers. | aspirin-related peptic ulcers are a common disorder. however, whether or not aspirin should be continued during treatment for aspirin-related ulcers remains unclear. | 2012 | 22508148 |
| proton pump inhibitors and risk of periampullary cancers--a nested case-control study. | considerable attention has been focused on long-term use of proton pump inhibitor (ppi) medications in relation to increased risk of cancer via stimulation of dna-damaged cells. the aim of this study is to examine the dose-dependent effect of ppi on periampullary cancers in a national population-based cohort. a nested case-control analysis was constructed based on taiwan's national health insurance research database and the taiwan cancer registry between the years 2000 and 2010. cases involving ... | 2016 | 26488896 |
| helicobacter pylori is not the predominant etiology for liver cirrhosis patients with peptic ulcer disease. | patients with liver cirrhosis (lc) often develop peptic ulcers. the differentiation of helicobacter pylori etiology in lc patients from that of peptic ulcers in non-lc patients is critical. this study aimed to determine whether h. pylori plays a central role in lc patients with peptic ulcers. | 2013 | 23044811 |
| the benefit of mass eradication of helicobacter pylori infection: a community-based study of gastric cancer prevention. | to evaluate the benefit of mass eradication of helicobacter pylori infection in reducing premalignant gastric lesions. | 2013 | 22698649 |
| diabetes, insulin use and helicobacter pylori eradication: a retrospective cohort study. | diabetic patients may have a higher risk of gastric cancer. however, whether they have a higher incidence of helicobacter pylori (hp) eradication is not known. furthermore, whether insulin use in patients with type 2 diabetes may be associated with a higher incidence of hp eradication has not been investigated. | 2012 | 22571603 |
| association between helicobacter pylori infection and dementia. | dementia is the severe loss of global cognitive ability in a previously healthy person. this study examined the relationship between helicobacter pylori infection (hp-i) and non-alzheimer's dementia (non-ad) using a nationwide population-based dataset. the international classification of diseases, ninth revision (icd-9) codes for dementia were used to define dementia patients; in addition, we examined the association of dementia with other comorbidities. patients aged ≥40years with newly diagnos ... | 2014 | 24629396 |
| increased incidence of herpes zoster in adult patients with peptic ulcer disease: a population-based cohort study. | peptic ulcer disease (pud) has been linked to immunological dysfunctions and malnutrition—both are predictors of herpes zoster(hz). we hypothesized that pud patients might have a greater risk for developing hz. | 2013 | 24536094 |
| hybrid vs sequential therapy for eradication of helicobacter pylori in taiwan: a prospective randomized trial. | to evaluate the efficacy of sequential vs hybrid therapy in patients with helicobacter pylori (h. pylori) infection. | 2015 | 26420970 |
| contribution of dna repair xeroderma pigmentosum group d genotype to gastric cancer risk in taiwan. | it has been proposed that genetic variations of dna repair genes confer susceptibility to cancer, and the dna repair gene xeroderma pigmentosum group d (xpd), the caretaker of genome stability, is thought to play a major role in the nucleotide excision repair system. we investigated three genotypes of xpd, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with gastric cancer susceptibility in a taiwanese population. | 2015 | 26254397 |
| h. pylori management in asean: the bangkok consensus report. | helicobacter pylori (h. pylori) infection remains to be the major cause of important upper gastrointestinal diseases such as chronic gastritis, peptic ulcer, gastric adenocarcinoma and mucosa-associated lymphoid tissue (malt) lymphoma. h. pylori management in asean: the bangkok consensus report gathered key opinion leaders for the region to review and evaluate clinical aspects of h. pylori infection and to develop consensus statements, rationales and grades of recommendation for the management o ... | 2017 | 28762251 |
| association of vagotomy and decreased risk of subsequent ischemic stroke in complicated peptic ulcer patients: an asian population study. | the primary management of peptic ulcers is medical treatment. persistent exacerbation of a peptic ulcer may lead to complications (perforation and/or bleeding). there has been a trend toward the use of a less invasive surgical simple suture, simple local suture or non-operative (endoscopic/angiography) hemostasis rather than acid-reducing vagotomy (i.e., vagus nerve severance) for treating complicated peptic ulcers. other studies have shown the relationship between high vagus nerve activity and ... | 2017 | 28726018 |
| ten-day quadruple therapy comprising proton pump inhibitor, bismuth, tetracycline, and levofloxacin is more effective than standard levofloxacin triple therapy in the second-line treatment of helicobacter pylori infection: a randomized controlled trial. | proton pump inhibitor (ppi)-amoxicillin-fluoroquinolone triple therapy is recommended as a second-line treatment of helicobacter pylori infection in the maastricht v/florence consensus report. however, the eradication rate of this standard salvage treatment is suboptimal. the objective of this study is to compare the efficacy of esomeprazole-bismuth-tetracycline-levofloxacin therapy (tl quadruple therapy) and esomeprazole-amoxicillin-levofloxacin triple therapy (al triple therapy) in rescue trea ... | 2017 | 28719592 |
| sequential therapy achieves a higher eradication rate than standard triple therapy in taiwan. | most clinical trials concerning sequential therapy have been conducted in italy. the efficacy of sequential therapy for helicobacter pylori (h. pylori) eradication in asia remains unclear. the aim of this study was to compare the efficacy of sequential therapy with standard triple therapy in taiwan. | 2012 | 21871025 |
| socioeconomic status, personal habits, and prevalence of helicobacter pylori infection in the inhabitants of lanyu. | lanyu island is a closed environment inhabited by the yami people, taiwan's smallest and most primitive tribe. this study assessed the prevalence and risk factors of helicobacter pylori infection among lanyu island residents. | 2014 | 24389268 |
| synergistic effect of hyperglycemia and helicobacterpylori infection status on colorectal adenoma risk. | both helicobacter pylori and type 2 diabetes mellitus are possible risk factors for colon adenoma. | 2017 | 28475740 |
| [is sequential eradication of helicobacter pylori effective? sequential treatment more effective than triple therapy in patients with clarithromycin resistance]. | | 2013 | 23512360 |
| medical risk factors associated with cholangiocarcinoma in taiwan: a population-based case-control study. | cholangiocarcinoma, including intra- and extrahepatic cholangiocarcinoma, is a rare but highly lethal cancer. despite effort in finding the risk factors of cholangiocarcinoma, the causes of most cholangiocarcinoma remain unknown. this study utilized a population-based case-control design using data from the national health insurance research database (nhird) of taiwan to assess the medical conditions associated with cholangiocarcinoma. | 2013 | 23894567 |