the chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation. | the obligate intracellular bacterial pathogen chlamydophila abortus strain s26/3 (formerly the abortion subtype of chlamydia psittaci) is an important cause of late gestation abortions in ruminants and pigs. furthermore, although relatively rare, zoonotic infection can result in acute illness and miscarriage in pregnant women. the complete genome sequence was determined and shows a high level of conservation in both sequence and overall gene content in comparison to other chlamydiaceae. the 1,14 ... | 2005 | 15837807 |
sequencing of the chlamydophila psittaci ompa gene reveals a new genotype, e/b, and the need for a rapid discriminatory genotyping method. | twenty-one avian chlamydophila psittaci isolates from different european countries were characterized using ompa restriction fragment length polymorphism, ompa sequencing, and major outer membrane protein serotyping. results reveal the presence of a new genotype, e/b, in several european countries and stress the need for a discriminatory rapid genotyping method. | 2005 | 15872282 |
[chlamydia: diagnostic and treatment]. | chlamydia are obligate intracellular bacteria. three species are considered human pathogens. chlamydophila pneumoniae is one of the most common agents of atypical community-acquired pneumonia. chlamydophila psittaci causes psittacosis, a severe zoonotic pneumonia transmitted by birds. finally, chlamydia trachomatis is the etiologic agent of trachoma and urogenital infections. the latter are commonly asymptomatic or paucisymptomatic. thus, they may remain undiagnosed for years, leading to serious ... | 2005 | 15895932 |
high risk of schizophrenia and other mental disorders associated with chlamydial infections: hypothesis to combine drug treatment and adoptive immunotherapy. | many microbial factors have been implicated as pathogenic factors in mental disorders. occurrence of such microbial factors also in the mentally unaffected population raised skepticism against such findings, although each microbial factor may cause mental problems only in some individuals, depending on the individual's immunogenetic disposition. skepticism against the role of infection in schizophrenia was also fostered by the low impact of antiinfections treatment on the course of disease progr ... | 2005 | 15922095 |
isolation of psittacosis agents from follicular conjunctivitis of sheep. | | 1967 | 15938284 |
epidemiological investigation of chlamydophila psittaci in pigeons and free-living birds in croatia. | during 2003, 278 adult pigeons (columba livia) and 54 birds of 11 other free-living species were caught in the various locations in the city of zagreb, croatia. sera from 182 pigeons were tested for the presence of antibodies against chlamydophila (c.) psittaci by elisa test and 174 of them (95.6%) were found positive. because of the high positivity rate in sera, cloacal swabs of 278 pigeons as well as 54 other species of free-living birds were tested for the presence of c. psittaci antigen. fou ... | 2005 | 15943062 |
high prevalence of chlamydial (chlamydophila psittaci) infection in fetal membranes of aborted equine fetuses. | seventy-seven cases of equine abortion from 49 hungarian farms that occurred between 1998 and 2000 were investigated for the presence of chlamydiae by immunohistochemistry, pcr and/or mzn staining. evidence of the presence of these bacteria was obtained in 64 cases (83.1%) from 41 (83.7%) different farms. partial ompa gene sequencing of pcr products revealed that the agent was chlamydophila psittaci. based on the findings of microbial diagnosis, pathology and case history, chlamydial infection w ... | 2005 | 15943064 |
influence of the th2 immune response established by nippostrongylus brasiliensis infection on the protection offered by different vaccines against chlamydophila abortus infection. | chlamydophila abortus is the aetiological agent of enzootic abortion in small ruminants in which it infects the placenta to cause abortion during the last trimester of gestation. in a mouse model, a th1 immune response involving ifn-gamma production and cd8+ t cells is necessary for the infection to be resolved. the authors previously demonstrated that infection with nippostrongylus brasiliensis, a rodent gastrointestinal nematode extensively used in experimental models to induce th2 responses, ... | 2005 | 15943065 |
diagnosis of ovine chlamydial abortions by pcr-rflp performed on vaginal swabs. | ovine enzootic abortion is an infectious and contagious disease clinically characterized by abortion and weak neonates, affecting sheep and goats. the etiological agent is chlamydophila (c.) abortus, which is considered one of the most common animal pathogens of small ruminants; it has important economic implications and represents a significant zoonotic risk. clinical diagnosis is often difficult because the clinical signs and the pathological lesions are not specific for c. abortus infection, ... | 2005 | 15943069 |
detection of chlamydophila abortus in sheep and goat flocks in southern italy by pcr using four different primer sets. | an epidemiological survey was performed to detect the presence of chlamydophila (c.) abortus and other members of the order chlamydiales in ovine and caprine flocks with a history of abortion in southern italy. four pairs of primers were compared to evaluate their ability to detect chlamydiales using purified dna preparations and tissue samples from aborted foetuses with suspected chlamydial infections. as expected, amplification of dna of the reference strain c. abortus using primer pairs u23f/ ... | 2005 | 15943070 |
feline chlamydiosis. | chlamydiae are an important cause of acute and chronic conjunctivitis in cats. until recently, only one organism was thought to infect cats, chlamydophila felis (previously chlamydia psittaci var. felis). recently, other chlamydia-like organisms belonging to the family parachlamydiaceae, which comprises organisms that reside and proliferate within free-living amoeba, have been identified in cats with neutrophilic and eosinophilic conjunctivitis. the relative importance of these organisms and the ... | 2005 | 15948428 |
another piece of the malt lymphomas jigsaw. | | 2005 | 15968002 |
regression of ocular adnexal lymphoma after chlamydia psittaci-eradicating antibiotic therapy. | some infectious agents contributing to lymphomagenesis have been considered targets for new therapeutic strategies. chlamydia psittaci dna has been detected in 80% of ocular adnexal lymphomas. the present pilot study was carried out to assess whether c psittaci-eradicating antibiotic therapy is associated with tumor regression in ocular adnexal lymphomas. | 2005 | 15968003 |
[dna extraction of chlamydophila psittaci from cloacal swabs and feces of birds]. | | 2005 | 15977554 |
frequency of spontaneous mutations that confer antibiotic resistance in chlamydia spp. | mutations in rrna genes (rrn) that confer resistance to ribosomal inhibitors are typically recessive or weakly codominant and have been mostly reported for clinical strains of pathogens possessing only one or two rrn operons, such as helicobacter pylori and mycobacterium spp. an analysis of the genome sequences of several members of the chlamydiaceae revealed that these obligate intracellular bacteria harbor only one or two sets of rrna genes. to study the contribution of rrna mutations to the e ... | 2005 | 15980362 |
[serologic examination of patients with prolonged cough in anamnesis]. | serological examinations of patients with prolonged cough in history, made at an allergy center, revealed, in 56% of them, igg to antigens of chlamydia pneumoniae and c. psittaci; antibodies to m. pneumonie were detected in 25% of them. it is expedient to diagnose serologically opportunistic infections in order to prevent chronic disease forms and further allergization. | 2005 | 15986800 |
protection of turkeys against chlamydophila psittaci challenge by dna and rmomp vaccination and evaluation of the immunomodulating effect of 1 alpha,25-dihydroxyvitamin d(3). | plasmid dna expressing the major outer membrane protein (momp) of an avian chlamydophila psittaci serovar d strain and recombinant momp (rmomp) with or without the immunomodulating adjuvant 1 alpha,25-dihydroxyvitamin d(3) have been tested for their ability to elicit an immune response and induce protection in turkeys against challenge with the same serovar. three vaccination strategies were compared: priming and boosting with either pcdna1::momp or rmomp and priming with pcdna1::momp followed b ... | 2005 | 16002193 |
isolation and identification of chlamydia psittaci in new zealand. | | 1986 | 16031216 |
[antibodies against chlamydophila in patients with acute myocardial infarction and coronary risk and their association with mortality]. | the primary aim of this study was to determine whether antibodies against chlamydophila pneumoniae in patients with acute myocardial infarction (ami) and coronary risk factors are associated with death. | 2005 | 16104465 |
[diagnostic tests: chlamydophila psittaci]. | | 2005 | 16111239 |
development of a chlamydophila psittaci species-specific and genotype-specific real-time pcr. | a chlamydophila psittaci species-specific real-time pcr targeting the rdna ribosomal spacer was developed as well as a genotype-specific real-time pcr targeting the cp. psittaci outer membrane protein a (ompa) gene. the sybr green-based species-specific real-time pcr detected cp. psittaci genotypes a to f, and the recently discovered e/b genotype. the genotype-specific real-time pcr could easily distinguish genotypes c, d, f by use of taqman probes. genotypes a, b and e could not be distinguishe ... | 2005 | 16120253 |
[the ideal woman...or almost!]. | | 2005 | 16129149 |
characterization of vaginal microflora of healthy, nonpregnant women by chaperonin-60 sequence-based methods. | the purpose of this study was to use a novel method that was based on the application of chaperonin-60 sequencing to describe the vaginal microflora of 16 healthy women. | 2005 | 16150261 |
ocular adnexal lymphoma: a clinicopathologic study of a large cohort of patients with no evidence for an association with chlamydia psittaci. | non-hodgkin lymphomas are among the most common primary tumors occurring in the ocular adnexa. herein, we present a 14-year single-institution experience in 62 patients with primary ocular adnexal lymphomas (oals). association with chlamydia psittaci infection is examined in 57 tumor specimens. extranodal marginal zone lymphoma (emzl) was the most frequent histologic subtype (89%). the majority of patients with emzl (84%) presented with stage e-extranodal (ie), however only 16% had an advanced s ... | 2006 | 16166588 |
cpg motifs as adjuvant in dna vaccination against chlamydophila psittaci in turkeys. | plasmid dna (pcdna1::momp) expressing the major outer membrane protein (momp) of an avian chlamydophila psittaci serovar d strain and recombinant momp (rmomp) with or without the immunomodulating cpg oligonucleotides (cpg on) were tested for their ability to elicit an immune response and to induce protection in turkeys against homologous challenge. two cpg on were chosen for in vivo application based on their in vitro capacity to stimulate the production of nitric oxide (no) in chicken macrophag ... | 2006 | 16183176 |
[atypical pneumonia]. | international epidemiologic surveys show that apart from community acquired "typical" pneumonia the number of cases caused by atypical pathogens are increasing. a number of problems are to be faced while diagnosing and treating the lower respiratory tract infections due to atypical pathogens. the article gives a detailed overview of pneumonia caused by chlamydia pneumoniae, chlamydia psittaci, mycoplasma pneumoniae, coxiella burnetti and legionella species, and emphasizes that these pathogens sh ... | 2005 | 16184877 |
use of a nested pcr-enzyme immunoassay with an internal control to detect chlamydophila psittaci in turkeys. | laboratory diagnosis of chlamydophila psittaci, an important turkey respiratory pathogen, is difficult. to facilitate the diagnosis, a nested pcr-enzyme immunoassay (pcr-eia) was developed to detect the cp. psittaci outer membrane protein a (ompa) gene in pharyngeal swabs. | 2005 | 16185353 |
detection of chlamydophila psittaci in asymptomatic animals. | | 2005 | 16208035 |
bacteriological survey of feces from feral pigeons in japan. | some public areas in japan such as parks and gardens can be highly contaminated with pigeon feces. we examined levels of four bacterial contaminations in fecal samples from feral pigeons in 7 prefectures. we isolated salmonella typhimurium and s. cerro from 17 (3.9%) of 436 samples, as well as mycobacterium spp. including m. avium-intracellulare complex from 29 (19.0%) of 153 samples. the polymerase chain reaction detected chlamydia psittaci and c. pecorum in 106 (22.9%) of 463 samples, but e. c ... | 2005 | 16210811 |
infectious disease and the decline of steller sea lions (eumetopias jubatus) in alaska, usa: insights from serologic data. | serologic data were examined to determine whether infectious disease may have played a role in the decline of steller sea lions (eumetopias jubatus) in the gulf of alaska and aleutian islands, usa. available published data, unpublished data, and recent collections (1997-2000) were compared and reviewed. data were stratified by geography to compare the declining western alaskan population in the aleutian islands through eastern prince william sound to the increasing population in southeastern ala ... | 2005 | 16244061 |
is there an association between ocular adnexal lymphoma and infection with chlamydia psittaci? the university of rochester experience. | various subsets of extranodal marginal zone lymphomas of mucosa-associated lymphoid tissues (malt lymphomas) have been associated with infectious organisms. most notable of these is the association of gastric malt lymphomas with helicobacter pylori infection. in a recent publication ferreri et al. [ferreri aj, guidoboni m, ponzoni m, de conciliis c, dell'oro s, fleischhauer k, et al. evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. j natl cancer inst 2004;96:5 ... | 2006 | 16246419 |
fitness cost due to mutations in the 16s rrna associated with spectinomycin resistance in chlamydia psittaci 6bc. | the fitness cost of a resistance determinant is the primary parameter that determines its frequency in vivo. as a model for analysis of the impact of drug resistance mutations on the intracellular life cycle of chlamydia spp., we studied the growth of four genetically defined spectinomycin-resistant (spc(r)) clonal variants of chlamydia psittaci 6bc isolated in the plaque assay. the development of each variant was monitored over 46 h postinfection in the absence of drug, either in pure culture o ... | 2005 | 16251283 |
an unusual cause of sepsis during pregnancy: recognizing infection with chlamydophila abortus. | chlamydophila abortus (formerly chlamydia psittaci serovar 1) is a rare but severe cause of gestational septicemia, with particular problems in diagnosis and clinical management. | 2005 | 16260577 |
prevalence of chlamydiae in boars and semen used for artificial insemination. | although there are indications for venereal transmission of chlamydiae in pigs, direct diagnostic evidence on the presence of these bacteria in boars and boar semen in particular is still incomplete. we investigated boars from two studs (a, b) in semen (a: n = 174; b: n = 100) and faeces (a: n = 174; b: n = 24) for chlamydiae using ompa-pcr and partial ompa gene sequencing. additionally, blood serum was examined for chlamydial antibodies using an indirect elisa (a: n = 171; b: n = 62). chlamydia ... | 2006 | 16280160 |
a monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates chlamydophila psittaci from chlamydophila pecorum, chlamydophila pneumoniae, and chlamydia trachomatis. | lipopolysaccharide (lps) of chlamydophila psittaci but not of chlamydophila pneumoniae or chlamydia trachomatis contains a tetrasaccharide of 3-deoxy-alpha-d-manno-oct-2-ulopyranosonic acid (kdo) of the sequence kdo(2-->8)[kdo(2-->4)] kdo(2-->4)kdo. after immunization with the synthetic neoglycoconjugate antigen kdo(2-->8)[kdo(2-->4)]kdo(2-->4) kdo-bsa, we obtained the mouse monoclonal antibody (mab) s69-4 which was able to differentiate c. psittaci from chlamydophila pecorum, c. pneumoniae, and ... | 2006 | 16282606 |
serotyping of us isolates of chlamydophila psittaci from domestic and wild birds. | the identities of chlamydial strains, which can infect a given host, are important to know for disease prognosis, disease control, and epidemiology. the microimmunofluorescence test (mift) was used with a panel of 14 serovar-specific monoclonal antibodies (mabs) to serotype 150 chlamydial isolates from domestic and wild birds. the isolates were obtained from birds submitted to diagnostic laboratories or during investigation of outbreaks. the 150 us isolates included 96 from the order psittacifor ... | 2005 | 16312243 |
therapeutic considerations about psittacosis: remarks on a case of family psittacosis. | | 1989 | 16312702 |
pathogenic interactions between chlamydophila psittaci and avian pneumovirus infections in turkeys. | both chlamydophila psittaci and avian pneumovirus (apv) are highly prevalent in belgian turkeys and might contribute to the respiratory disease complex observed in turkeys. initial outbreaks of chlamydiosis occur mostly at the age of 4-8 weeks, often accompanied by an apv infection in apv non-vaccinated farms. regardless apv vaccination, breakthroughs of apv infection from 8 weeks on do occur, a period when also a second c. psittaci infection appears. therefore, this study examined the pathogeni ... | 2006 | 16326044 |
association between helicobacter pylori infection and malt-type lymphoma of the ocular adnexa: clinical and therapeutic implications. | the prevalence and the clinical impact of gastric helicobacter pylori (hp) infection, as well as its possible correlation with chlamydia psittaci (cps) infection and the lymphoma regression rate produced by hp eradicating antibiotic therapy were investigated in patients with malt-type lymphoma of the ocular adnexa (oal). | 2006 | 16385613 |
selective indices on non-specific cell-mediated immunity in rabbits immunized with chlamydophila psittaci. | studies of non-specific immunity in infection or immunization with chlamydophila (chl.) psittaci in static experimental models showed changes in parameters of this immunity. the aim of this study was to evaluate selected parameters of non-specific immunity in rabbits immunized with chl. psittac. | 2005 | 16407786 |
no evidence for an association of ocular adnexal lymphoma with chlamydia psittaci in a cohort of patients from the netherlands. | extra-nodal marginal zone b cell lymphomas (mzbcls) of the mucosa-associated lymphoid tissues (malt) arise at sites of chronic antigenic stimulation due to organ-specific autoimmunity or infections, like helicobacter pylori-associated chronic gastritis and borrelia burgdorferi dermatitis. recently, conflicting data have been published regarding a possible association between chlamydia psittaci and ocular adnexal mzbcl. in the present study, we analyzed a cohort of ocular adnexal mzbls from the n ... | 2006 | 16420962 |
absence of chlamydia psittaci in ocular adnexal lymphoma from japanese patients. | | 2006 | 16445841 |
[community-acquired pneumonia with rhabdomyolysis]. | we assessed the frequency and etiology of rhabdomyolysis in patients with community-acquired pneumonia. in 594 patients with community-acquired pneumonia whose serum cpk were measured, 25 patients (2.4%) were found to have rhabdomyolysis. including 4 patients with mixed infections, the etiologies in 25 patients with community-acquired pneumonia with rhabdomyolysis were as follows: legionella species, 11 patients (44%); influenza virus, 6 (24%); streptococcus pneumoniae, 4 (16%); chlamydia psitta ... | 2005 | 16457334 |
[severe pneumonia from psittacosis in a bird-keeper]. | a 67-year-old man was admitted due to severe pneumonia. initially he was treated with beta-lactam antibiotics and oxygen. however, he developed respiratory failure and was transferred to the intensive-care unit for mechanical ventilation. he was a bird-keeper who collected many species of exotic birds, including parrots. the diagnosis psittacosis (parrot fever) was confirmed serologically and by pcr on bronchoalveolar lavage fluid. pcr techniques lead to rapid diagnosis which allows for early tr ... | 2006 | 16463610 |
[psittacosis outbreak in granada, spain]. | psittacosis can be transmitted to humans from infected birds, being the cause of atypical pneumonia. this work is aimed at determining the source of a psittacosis outbreak, the characteristics of the subjects exposed and describing the measures to control the outbreak. | 2005 | 16471138 |
development of a rapid real-time pcr assay for detection and quantification of four familiar species of chlamydiaceae. | chlamydiae are one of the causative agents of various diseases in animals and human beings, which include abortion, pneumonia, gastroenteritis, encephalomyelitis, conjunctivitis, arthritis and sexually transmitted diseases. much work has been carried out to attempt to develop an efficient pathogen detection strategy. here, we presented a chlamydiaceae-specific 23s rrna-based real-time pcr assay for simultaneous detection and quantification of four members of chlamydiaceae family, c. trachomatis, ... | 2006 | 16488188 |
chlamydophila psittaci in fulmars, the faroe islands. | chlamydophila psittaci was detected in 10% of 431 fulmars examined from the faroe islands. analysis of ompa showed a sequence almost identical to that of the type strain. the origin of c. psittaci outbreaks in fulmars is discussed. despite a high level of exposure, the risk for transmission of c. psittaci to humans is low. | 2006 | 16494766 |
'blind' antibiotic treatment targeting chlamydia is not effective in patients with malt lymphoma of the ocular adnexa. | recent results have implicated chlamydia, especially chlamydia psittaci, in the development of ocular adnexal lymphoma in the large majority of patients. we present our experience with ex-juvantibus antibiotic treatment in patients diagnosed with malt lymphoma of the ocular adnexa. | 2006 | 16500916 |
infectious agents in mucosa-associated lymphoid tissue-type lymphomas: pathogenic role and therapeutic perspectives. | mucosa-associated lymphoid tissue (malt) lymphoma probably constitutes the best in vivo model showing how complex interplay between b lymphocytes and the surrounding microenvironment may lead to a neoplastic disorder. after the seminal discovery of the pathogenic association between helicobacter pylori and gastric malt lymphomas, evidence suggests the possible involvement of other infectious agents in the development of malt lymphomas arising at different body sites. although several other bacte ... | 2006 | 16507206 |
marginal zone lymphoma. | marginal zone lymphomas (mzls) comprise 3 distinct entities: extranodal mzl of mucosa-associated lymphoid tissue (malt), splenic mzl, and nodal mzl. gastric malt lymphoma is the most common extranodal mzl and often develops as a result of chronic helicobacter pylori gastritis. such cases frequently respond to antibiotics directed against h. pylori. antigen-driven lymphomatous disease can also be seen in the association of borrelia burgdorferi with malt lymphoma of the skin, chlamydia psittaci wi ... | 2006 | 16507274 |
re: evidence for an association between chlamydia psittaci and ocular adnexal lymphomas. | | 2006 | 16507837 |
chlamydia psittaci in ocular adnexal lymphoma: japanese experience. | we searched for the chlamydia psittaci dna the touchdown enzyme time release pcr (tetr-pcr) in 23 specimens from 21 patients with ocular adnexal lymphoproliferative disorders, including 12 patients with malt lymphoma to identify c. psittaci infection. southern hybridization of the pcr product using the c. psittaci-specific probe failed to detect c. psittaci, although three samples appeared to be positive by ethidium bromide staining. this indicates that technical approach for detecting c. psitta ... | 2006 | 16524626 |
development of a real-time pcr for the detection of chlamydia psittaci. | | 2006 | 16533998 |
chlamydiae modulate gamma interferon, interleukin-1 beta, and tumor necrosis factor alpha receptor expression in hela cells. | chlamydia psittaci was found to modulate receptor expression for the cytokine receptors that are involved in the synergistic induction of indoleamine dioxygenase in epithelial cells. increases in receptor expression were seen even with inactivated chlamydia, suggesting that chlamydial antigens and not products of infection are important for up-regulating cytokine receptor expression. | 2006 | 16552084 |
[comparative studies on detection of chlamydophila psittaci and chlamydophila abortus in meat turkey flocks using cell culture, elisa, and pcr]. | the prevalence of chlamydia in 10 meat turkey flocks was investigated. as samples served of each moment of collection and sex of the animals 10 cloacal swabs which were taken at the age of 1, 4, 8 and 12 (females) or 16 weeks (males) and at the time of slaughter at the age of 16 or 20 weeks. spleen samples were taken at the time of slaughter, additionally. these were pooled making 1 pool out of 5 individual samples. the cloacal and spleen pools were examined by nested pcr (npcr), capture-elisa a ... | 2006 | 16555483 |
lipid composition of the hemagglutinating active fraction obtained from chick embryos infected with chlamydia psittaci 6bc. | the lipid composition of the concentrated hemagglutininating active fraction (hf) of allantoic fluid from infected eggs, but free from chlamydia psittaci 6bc, was compared to concentrated normal allantoic fluid (naf). phosphatidyl-choline (pc) and phosphatidylethanolamine were the major lipid classes of the total phospholipid fraction. some quantitative differences were found in the amount of pc and phosphatidylserine present in hf and naf. lysophosphatidylcholine was present in hf but absent in ... | 1970 | 16557838 |
inhibition of deoxyribonucleic acid synthesis in synchronized populations of l cells infected with chlamydia psittaci. | infection of l cells with chlamydia psittaci inhibited the burst of deoxyribonucleic acid synthesis that occurs when the host cells are released from a double thymidine block. | 1971 | 16557980 |
derivation of a borg strain of chlamydia psittaci attenuated for mice. | the method of derivation and virulence of a new attenuated variant (abg) obtained during passage of the virulent borg strain in embryonated eggs in the presence of p-aminobenzoic acid are described. | 1971 | 16558005 |
cell wall synthesis by chlamydia psittaci growing in l cells. | biochemical events accompanying changes in structure and behavior of the cell walls of chlamydia psittaci strain 6bc during its developmental cycle in l cells (mouse fibroblasts) were studied by measuring at short intervals the effect of d-cycloserine and penicillin g on incorporation of labeled intermediates into acid-insoluble fractions of infected l cells in which host incorporation had been inhibited by cycloheximide and into intact chlamydial cells and cell walls separated from the infected ... | 1970 | 16559091 |
glucose metabolism of l cells before and after infection with chlamydia psittaci. | glucose was not utilized at significantly different rates in suspensions of multiplying and nonmultiplying adult mouse fibroblasts (l cells). infection of l cells with chlamydia psittaci (strain meningopneumonitis) increased the rates of glucose utilization and lactate accumulation during the first 24 hr after infection without changing the rates of glucose utilization by the pentose or tricarboxylic acid cycles. it was concluded that the increased aerobic glycolysis represented a host response ... | 1970 | 16559092 |
electron microscopic observations on the fine structure of cell walls of chlamydia psittaci. | l-cell cultures were infected with elementary bodies (eb) of meningopneumonitis organisms. cell walls were prepared from reticulate bodies (rb), which are the intracellular developmental forms into which eb are converted, and from eb at appropriate times after infection. when fragmented eb cell walls were shadowcast with platinum palladium alloy, about one-half of the fragments were seen to be composed of hexagonally arrayed structures on the inner side of the cell wall. when eb cell walls were ... | 1970 | 16559112 |
pet ownership in immunocompromised children--a review of the literature and survey of existing guidelines. | pet ownership has been associated with both emotional and physical health benefits. however, owning pets may also pose health risks to immunocompromised patients through zoonotic transmission of disease. our initial impression was that there is a lack of any evidence base in information given by health care professionals regarding these risks. we therefore aimed to produce evidence-based guidelines addressing this issue. a pubmed search was undertaken and a variety of literature on zoonoses revi ... | 2006 | 16581294 |
chlamydia psittaci is variably associated with ocular adnexal malt lymphoma in different geographical regions. | infectious agents play a critical role in malt lymphoma development. studies from italy showed chlamydia psittaci infection in 87% of ocular adnexal malt lymphomas and complete or partial regression of the lymphoma after c. psittaci eradication in four of nine cases. however, c. psittaci was not demonstrated in ocular adnexal malt lymphomas from the usa. this study was thus designed to investigate further the role of c. psittaci, and other infectious agents commonly associated with chronic eye d ... | 2006 | 16583361 |
sepsis due to gestational psittacosis: a multidisciplinary approach within a perinatological center--review of reported cases. | chlamydia psittaci is associated with significant morbidity and mortality during pregnancy, and its rarity can delay early diagnosis and treatment. a farmer's wife presented at 31 weeks with febrile illness and developed signs of septic shock, indicating immediate delivery. the child developed uneventfully. the mother survived after symptomatic mechanical ventilation, including extracorporeal lung assistance, for 11 days due to multi-organ failure. only two weeks after admission antibody titres ... | 2006 | 16596904 |
an investigation into the role of chlamydophila spp. in bovine upper respiratory tract disease. | an outbreak of upper respiratory tract disease was investigated in a group of 17 housed home-bred calves on a mixed dairy, beef and sheep farm in devon. conjunctival swabs were collected and tested for chlamydophila spp. dna using a pcr test that detects chlamydophila abortus and chlamydophila psittaci. six of the calves tested gave a positive result. further epidemiological observations and laboratory testing indicated that the adult dairy cows, from which the affected calves originated, were t ... | 2006 | 16624729 |
ocular adnexal lymphoma: a review of clinicopathologic features and treatment options. | the recent literature shows that interest in ocular adnexal lymphomas and their biologic and clinical characteristics--along with their possible association with chlamydia psittaci infection and therapeutic management with rituximab or anti-chlamydia psittaci antibiotic therapy--is considerable. these new data have modified the previously reported features of this disease and have made an updated review of the literature necessary. the aims of this review are to present the current knowledge on ... | 2006 | 16638927 |
the atypical pneumonias: clinical diagnosis and importance. | the most common atypical pneumonias are caused by three zoonotic pathogens, chlamydia psittaci (psittacosis), francisella tularensis (tularemia), and coxiella burnetii (q fever), and three nonzoonotic pathogens, chlamydia pneumoniae, mycoplasma pneumoniae, and legionella. these atypical agents, unlike the typical pathogens, often cause extrapulmonary manifestations. atypical caps are systemic infectious diseases with a pulmonary component and may be differentiated clinically from typical caps by ... | 2006 | 16669925 |
inclusion proteins of chlamydiaceae. | chlamydiaceae are obligate intracellular pathogens with family members among the etiological agents of several human diseases, such as blinding trachoma, sexually transmitted disease (chlamydia trachomatis) and pneumonia (chlamydophila pneumoniae, chlamydophila psittaci). the bacteria replicate intracellularly in a membrane-bound vacuole termed inclusion. the chlamydial inclusion is effectively separated from eukaryotic endocytic pathways. more than two decades ago it was already speculated that ... | 2006 | 16683046 |
hematology, plasma chemistry, and serology of the flightless cormorant (phalacrocorax harrisi) in the galapagos islands, ecuador. | the flightless cormorant (phalacrocorax harrisi) is an endemic species of the galápagos islands, ecuador. health studies of the species have not previously been conducted. in august 2003, baseline samples were collected from flightless cormorant colonies on the islands of isabela and fernandina. seventy-six birds, from nestlings to adults, were evaluated. genetic sexing of 70 cormorants revealed 37 females and 33 males. hematology assessment consisted of packed cell volume (n=19), leukograms (n= ... | 2006 | 16699155 |
development of an internally controlled real-time pcr assay for detection of chlamydophila psittaci in the lightcycler 2.0 system. | a real-time pcr assay with a dna purification and inhibition control (internal control; ic) was developed to detect chlamydophila psittaci dna in human clinical samples. novel c. psittaci-specific primers targeting the ompa gene were developed. the ic dna contained the same primer-binding sites and had the same length and nucleotide content as the c. psittaci dna amplicon, but had a shuffled probe-binding region. the lower limit of detection was 80 target copies/pcr, corresponding to 6,250 copie ... | 2006 | 16700707 |
evaluation of a recombinant enzyme-linked immunosorbent assay for detecting chlamydophila psittaci antibodies in turkey sera. | chlamydophila psittaci (formerly chlamydia psittaci) is one of the major pathogens associated with turkey respiratory disease. devastating outbreaks with high mortality rates, similar to those of 1950 to 1970 in the usa occasionally occur, but respiratory signs without or with low mortality mostly characterize outbreaks now a day. accurate diagnostic methods should be made available. the present study examined the sensitivity and specificity of a recombinant elisa (rmomp elisa) for detecting cp. ... | 2006 | 16701067 |
evaluation of progesterone, estrogens and placental lactogen in pregnant ewes following experimental infection with an abortive agent chlamydia psittaci "var-ovis". | the plasma levels of progesterone, free and conjugated estrone and of placental lactogen have been determined in three groups of pregnant ewes inoculated with an abortive agent (chlamydia psittacci var. ovis) on day 66 of gestation. in the control group, ewes were immunized against this abortive agent, and lambed after a normal duration of pregnancy; the blood levels of the three studied hormones showed normal patterns. in the two other groups, the ewes which were not immunized, had a shortened ... | 1981 | 16725643 |
development potential of rifalazil and other benzoxazinorifamycins. | rifalazil and other benzoxazinorifamycins (new chemical entities [nces]) are rifamycins that contain a distinct planar benzoxazine ring. rifalazil has excellent antibacterial activity, high intracellular levels and high tissue penetration, which are attributes that favour its use in treating diseases caused by the obligate intracellular pathogens of the genus chlamydia. recent studies have shown that rifalazil has efficacy in the treatment of human sexually transmitted disease caused by chlamydi ... | 2006 | 16732714 |
prevalence of chlamydophila psittaci in fecal droppings from feral pigeons in amsterdam, the netherlands. | in many cities, the feral rock dove is an abundant bird species that can harbor chlamydophila psittaci. we determined the prevalence and genotype of c. psittaci in fresh fecal samples from feral pigeons in amsterdam, the netherlands. the prevalence was 7.9% overall (26/331; 95% confidence interval, 5 to 11). ten genotyped pcr-positive samples were all genotype b. | 2006 | 16751560 |
enucleated l929 mouse fibroblasts support invasion and multiplication of shigella flexneri 5a. | invasive bacteria can induce their own uptake and specify their intracellular localization; hence it is commonly assumed that proximate modulation of host cell transcription is not required for infection. however, bacteria can also modulate, directly or indirectly, the transcription of many host cell genes, whose role in the infection may be difficult to determine by global gene expression. is the host cell nucleus proximately required for intracellular infection and, if so, for which pathogens ... | 2006 | 16751980 |
evaluation of the persistence and gene expression of an anti-chlamydophila psittaci dna vaccine in turkey muscle. | dna vaccination has been shown to elicit specific cellular and humoral immune responses to many different agents in a broad variety of species. however, looking at a commercial use, the duration of the immune response against the vaccine is critical. therefore the persistence of the dna vaccine, as well as its expression, should be investigated. we conducted these investigations on a dna vaccine against chlamydophila psittaci, a gram-negative intracellular bacterium which causes respiratory dise ... | 2006 | 16764710 |
genome sequence of the cat pathogen, chlamydophila felis. | chlamydophila felis (chlamydia psittaci feline pneumonitis agent) is a worldwide spread pathogen for pneumonia and conjunctivitis in cats. herein, we determined the entire genomic dna sequence of the japanese c. felis strain fe/c-56 to understand the mechanism of diseases caused by this pathogen. the c. felis genome is composed of a circular 1,166,239 bp chromosome encoding 1005 protein-coding genes and a 7552 bp circular plasmid. comparison of c. felis gene contents with other chlamydia species ... | 2006 | 16766509 |
rapidly increasing incidence of ocular non-hodgkin lymphoma. | a recent report suggesting that ocular adnexal non-hodgkin lymphoma (nhl) may be related to chlamydia psittaci infection underscores the need for reliable epidemiologic data for this malignancy. we examined population-based incidence data from the surveillance, epidemiology, and end results (seer) program. during 1992-2001 in the 12 seer areas, ocular (i.e., eye and adnexa) nhl rates per 100,000 person-years for both sexes were highest among asians/pacific islanders, lower in whites, and lower s ... | 2006 | 16818858 |
transcriptional response patterns of chlamydophila psittaci in different in vitro models of persistent infection. | the obligatory intracellular bacterium chlamydophila psittaci is the causative agent of psittacosis in birds and humans. the capability of this zoonotic pathogen to develop a persistent phase is likely to play a role in chronicity of infections, as well as in failure of antibiotic therapy and immunoprophylaxis. to elucidate three different in vitro models for transition of c. psittaci to persistence (iron depletion, penicillin g treatment, and gamma interferon [ifn-gamma] exposure), a set of 27 ... | 2006 | 16861668 |
chlamydophila psittaci in free-living blue-fronted amazon parrots (amazona aestiva) and hyacinth macaws (anodorhynchus hyacinthinus) in the pantanal of mato grosso do sul, brazil. | chlamydophila psittaci (c. psittaci) infection was evaluated in 77 free-living nestlings of blue-fronted amazon parrots (amazona aestiva) and hyacinth macaws (anodorhynchus hyacinthinus) in the pantanal of mato grosso do sul, brazil. tracheal and cloacal swab samples from 32 wild parrot and 45 macaw nestlings were submitted to semi-nested pcr, while serum samples were submitted to complement fixation test (cft). although all 32 amazon parrot serum samples were negative by cft, cloacal swabs from ... | 2006 | 16893616 |
detection by broad-range real-time pcr assay of chlamydia species infecting human and animals. | tests available for molecular diagnosis of chlamydial infections detect chlamydiatrachomatis, but do not find other chlamydia species associated with genital, ophthalmic, cardiovascular, respiratory or neurological diseases. the routine detection of all chlamydia species would improve the prognosis of infected people and guide therapeutic choices. | 2006 | 16899531 |
exacerbation of chlamydophila psittaci pathogenicity in turkeys superinfected by escherichia coli. | both chlamydophila psittaci and escherichia coli infections are highly prevalent in belgian turkeys and therefore they both might contribute to the respiratory disease complex observed in turkeys. c. psittaci can infect turkeys within the first week of age, even in the presence of maternal antibodies. however, the first c. psittaci outbreaks occur mostly at the age of 3 to 6 weeks, the period when also e. coli infections appear on the farms. therefore, we examined in this study the pathogenicity ... | 2006 | 16973115 |
genetic diversity and epizootiology of chlamydophila psittaci prevalent among the captive and feral avian species based on vd2 region of ompa gene. | to study genetic diversity and occurrence of chlamydophila psittaci, a total of 1,147 samples from 11 avian orders including 53 genera and 113 species of feral and captive birds were examined using ompa gene based nested pcr. three types of chlamydiae: c. psittaci (94.12%), c. abortus (4.41%) and unknown chlamydophila sp. (1.47%) were identified among 68 (5.93%) positive samples (psittaciformes-59, ciconiiformes-8 and passeriformes-1). based on nucleotide sequence variations in the vd2 region of ... | 2006 | 16985288 |
comparative pcr-based restriction fragment length polymorphism analysis of the plasmid gene orf3 of chlamydia trachomatis and chlamydia psittaci. | the bfai digestion of pcr-based restriction fragment length polymorphism analysis of the plasmid orf3 of chlamydia trachomatis and chlamydia psittaci provided evidence for two distinct restriction patterns, respectively. the nucleotide sequences of orf3 genes confirmed these differences. serum antibodies against recombinant c. psittaci protein (pgp3) encoded by orf3 were detected both in pigeons with c. psittaci infection and in a human patient with psittacosis. | 2006 | 16999825 |
chlamydia and mycoplasma serology in respiratory tract infections of children. | one of the challenges in planning the treatment of respiratory tract infection in children is identifying the causative agent. the objective of the present study was to investigate the incidence of mycoplasma and chlamydia in the etiology of respiratory tract infections of children. the present study included 100 children, three months to 12 years of age, admitted to the outpatient department of pediatrics with such respiratory symptoms as fever, cough and respiratory distress. following a detai ... | 2006 | 17001543 |
chlamydia or not chlamydia, that is the question: which is the microorganism associated with malt lymphomas of the ocular adnexa? | | 2006 | 17018775 |
bacteria-eradicating therapy with doxycycline in ocular adnexal malt lymphoma: a multicenter prospective trial. | an association between ocular adnexal malt lymphoma (oal) and chlamydia psittaci (cp) infection has been proposed, and recent reports suggest that doxycycline treatment causes tumor regression in patients with cp-related oal. the effectiveness of doxycycline treatment in cp-negative oal has not been tested. | 2006 | 17018784 |
up-regulation of gamma interferon receptor expression due to chlamydia-toll-like receptor interaction does not enhance signal transducer and activator of transcription 1 signaling. | gamma interferon (ifn-gamma)-induced indoleamine dioxygenase (ido), which inhibits chlamydial replication by reducing the availability of tryptophan, is up-regulated by interleukin-1beta (il-1beta) and tumor necrosis factor alpha (tnf-alpha). the mechanisms by which this occurs include an increase in the synthesis of interferon regulatory factor-1 as well as a nuclear factor-kappab (nf-kappab)-dependent increase in the expression of ifn-gamma receptors (ifn-gammar). although chlamydia is suscept ... | 2006 | 17030574 |
an outbreak of psittacosis due to chlamydophila psittaci genotype a in a veterinary teaching hospital. | an outbreak of psittacosis in a veterinary teaching hospital was recognized in december 2004. outbreak management was instituted to evaluate the extent of the outbreak and to determine the avian source. real-time pcr, serologic testing and sequencing of the ompa gene of chlamydophila psittaci were performed. sputum samples from patients, throat-swab samples from exposed students and staff, and faecal specimens from parrots and pigeons were tested. in this outbreak, 34 % (10/29) of the tested ind ... | 2006 | 17030918 |
[a case of psittacosis showing a localized peripheral air-space consolidation]. | a 29-year-old man was admitted with fever and anorexia. radiographic examinations of the chest showed a localized peripheral non-segmental air-space consolidation in the right lower lobe. he had a history of exposure to parakeets, and psittacosis was diagnosed based on the elevated serum complement fixation titer against chlamydia psittaci. the common radiographic finding of psittacosis is ground-glass attenuation radiating from the hilar areas. we report a rare case of psittacosis presenting a ... | 2006 | 17037414 |
psittacosis in all four members of a family in nagasaki, japan. | | 2006 | 17060709 |
lymphomas involving the eye and the ocular adnexa. | to describe recent advances in the understanding of the pathogenesis of the most common malignant lymphomas that occur as primary and secondary tumors in ocular tissues. | 2006 | 17065920 |
hematology, serum chemistry, and serology of galápagos penguins (spheniscus mendiculus) in the galápagos islands, ecuador. | the galápagos penguin (spheniscus mendiculus) is an endangered species endemic to the galápagos islands, ecuador. in 2003 and 2004, 195 penguins from 13 colonies on the islands of isabela and fernandina in the galápagos archipelago were examined. genetic sexing of 157 penguins revealed 62 females and 95 males. hematology consisted of packed cell volume (n = 134), white blood cell differentials (n = 83), and hemoparasite blood smear evaluation (n = 114). microfilariae were detected in 22% (25/114 ... | 2006 | 17092893 |
associations between chlamydophila infections, schizophrenia and risk of hla-a10. | several microbes have been suspected as pathogenetic factors in schizophrenia. we have previously observed increased frequencies of chlamydial infections and of human lymphocyte antigen (hla)-a10 in independent studies of schizophrenia. our aim here was to analyze frequencies of three types of chlamydiaceae in schizophrenic patients (n=72), random controls (n=225) and hospital-patient controls (n=36), together with hla-a genotypes. patients were diagnosed with schizophrenia according to diagnost ... | 2007 | 17102800 |
[bilateral lung consolidations related to accidental exposure to parrots]. | the authors present the case of a 32 years male patient admitted for lung consolidations with bilateral extension tendency, associated to fever, respiratory failure and hepatic involvement, with a sudden onset two weeks after contact with apparently healthy parrots. bronchiolo-alveolar lavage was suggestive for a hypersensitivity pneumonia, but the clinical evolution was good with antibiotics (macrolides, than doxycycline). radiologic resolution was spectacular. serum antibodies anti-ch. psittac ... | 2006 | 17144482 |
determination of the inhibitory concentration 50% (ic50) of four selected drugs (chlortetracycline, doxycycline, enrofloxacin and difloxacin) that reduce in vitro the multiplication of chlamydophila psittaci. | a total of 18 chlamydial isolates from various psittacine birds, one isolate from a domestic pigeon and one isolate from a pekin duck were isolated in continuous buffalo green monkey (bgm) kidney cell cultures. all 20 isolates were identified by nested multiplex polymerase chain reaction as chlamydophila psittaci. these isolates were multiplied to high titres and subsequently tested for in vitro sensitivity against two tetracyclines (chlortetracycline and doxycycline) and two quinolones (enroflo ... | 2006 | 17147151 |
a pmp genes-based pcr as a valuable tool for the diagnosis of avian chlamydiosis. | in a previous study we described the use of a new set of pcr primers (cpsia/cpsib) specific of the conserved pmp-family genes of chlamydophila abortus as an efficient tool for the detection of these bacteria in ruminants including also preliminary results on avian strains. in this work, the use of this set of primers was extended to representative strains of the six major avian serovars (serovars a-f) and to field isolates of c. psittaci. for all the studied representative strains, using purifie ... | 2007 | 17169505 |
co-infection with two chlamydophila species in a case of fulminant myocarditis. | the aim of this study is to describe a case of fulminant myocarditis caused by co-infection with chlamydophila pneumoniae and chlamydophila psittaci in order to facilitate diagnosis and clinical management of patients suffering from this rare but life-threatening condition. | 2007 | 17204998 |
lack of microbial dna in tissue specimens of patients with abdominal aortic aneurysms and positive chlamydiales serology. | in a case-control study that included a total of 98 patients and 83 controls, the possible link between various pathogens and abdominal aortic aneurysms was investigated. for 68 patients with abdominal aortic aneurysm and age-matched controls, no differences were detected in the levels of immunoglobulin (ig)a and igg chlamydiaceae and chlamydophila pneumoniae antibodies. patients with iga titers positive for chlamydophila pneumoniae showed progressive disease (defined as an annual increase of th ... | 2007 | 17216421 |
serologic survey for pathogens potentially affecting pronghorn (antilocapra americana) fawn recruitment in arizona, usa. | during the 1990s, pronghorn (antilocapra americana) populations declined in arizona, usa. to investigate potential causes of decline, we collected blood samples from hunter-harvested male pronghorn from 2001 to 2003 on four arizona sites. sera were tested for antibody to parainfluenza virus type 3 (pi3), bovine viral diarrhea virus, infectious bovine rhinotracheitis virus, bovine respiratory syncytial virus, epizootic hemorrhagic disease virus (ehdv), bluetongue virus (btv), and chlamydia psitta ... | 2006 | 17255453 |