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preparation of single bilayer liposomes by an electrocapillary emulsification method.the single bilayer liposomes have been prepared by an electrocapillary emulsification technique based on interfacial fluctuation in the absence of surfactant. electron microscopy showed the liposome to be a unilamellar vesicle with a size generally in the range 60-120 nm.20102872295
relationships among duration of infusion, dose, dosing interval, and steady-state plasma concentrations during intermittent intravenous infusions: studies with metronidazole.relationships among duration of infusion (t), dose, dosing interval (tau), maximum and minimum plasma drug concentrations at steady state (cmax,ss and cmin,ss, respectively), and the duration of effective plasma concentrations (td) during multidose intermittent infusion regimens were studied by computer simulation using metronidazole as a model drug. pharmacokinetic parameter values for metronidazole were obtained from the literature and the minimum effective plasma concentration (mec) was taken ...20113746634
histopathological studies of the temporal bones in hurler's disease [mucopolysaccharidosis (mps) ih].the structural basis of the combined conductive and sensorineural deafness has been described in two patients with hurler's disease. all parts of the ear contained numerous large vacuolated hurler cells, the vacuoles being distended lysosomes from which accumulated glycosaminoglycans had been dissolved during fixation of the tissue. the external and middle ears also showed chronic inflammation. there was resorption of the bone in the mastoid process by masses of hurler cells and abnormal new bon ...20113918131
[difficulties in otolaryngologic practice in central africa]. 20113237415
achondroplasia in sibs of normal parents.a new case of recurrent achondroplasia in sibs of normal parents is reported. two sisters and a half sister were affected. various mechanisms can be postulated to account for unexpected recurrence of achondroplasia in the same sibship. germinal mosaicism and unstable premutation are discussed here.20113236371
relationship of lateral eye movements recorded in the dark to verbal and spatial question types.lateral eye movements (lems) were recorded in normal subjects to verbal and spatial questions in the dark using infra-red recording techniques to assess whether clearer lem-question type relationships are observed when the potentially confounding effects of visual stimulation are absent. verbal questions elicited more rightward lems than spatial questions. however, spatial questions were not associated with leftward lems. it is argued that while infra-red recording techniques may be optimal for ...20113194056
[aids and nursing care. how far will aids take us?]. 20113204982
hazardous effects of disinfection and sterilization chemicals. 20113215342
pseudoachondroplasia with immune deficiency.a 5-year-old boy was admitted to the hospital with failure to thrive since he was 2 years old, with weakness in his legs and a waddling gait. he has normal mental development. his parents are normal phenotypically and are unrelated. in analyzing his pedigree only a grandfather is described to have waddling gait. he has a normal craniofacial appearance but a disproportionate body with normal trunk and short extremities with height below the 3rd percentile. the diagnosis of pseudoachondroplasia wa ...20113263611
[southern sudan: health project in the middle of a civil war. nursing; open to multiple health possibilities]. 20113187334
aids speakers bureau--activities update. 20113210988
stress in health visiting: qualitative accounts. 20113198410
psychopharmacological effects of sertraline in normal, healthy volunteers.a double-blind, placebo controlled, cross-over study was carried out in 10 normal healthy volunteers to investigate the effects of sertraline 25 mg, 50 mg, 75 mg and 100 mg on aspects of cognitive functioning. changes with respect to placebo in objective tests of psychomotor function (critical flicker fusion and choice reaction time) showed that sertraline had an alerting effect. the changes were not consistent with subjective reports of drowsiness.20113191944
proceedings of the 27th scandinavian congress of neurology. kuopio, finland, june 15-18, 1988. 20113165580
south african gem of medical history. 20113147784
one year's experience with the gift method.from january 1985 to december 1985 we have performed 83 gifts for various indications such as unexplained infertility, immunological problems, endometriosis, male factor, fimbrial pathology. in 82 women out of 83, oocytes and sperm have been transferred and 31 pregnancies (37.8%) have been obtained. twelve women have delivered 17 babies; 11 pregnancies are ongoing, 7 have been interrupted by an abortion and 1 by a tubal pregnancy. the present and future roles of gift in the treatment of infertil ...20113739561
disease and pregnancy in adolescent girls.the frequency of visits to the outpatient clinic, chief complaints, and pregnancies of adolescent girls were analyzed. the age distribution of adolescent girls who visited the clinic showed that the higher the age, the higher the frequency of menstrual cycle abnormalities. recently, increased sexual activity has been seen in teenagers and has caused problems, especially the increase in teenage pregnancies, contributing to increases in induced abortion. to avoid unwanted pregnancy of unmarried te ...20113252729
multiple apparently unrelated clonal chromosome abnormalities in a squamous cell carcinoma of the tongue.we have cytogenetically examined short-term cultures from a squamous cell carcinoma of the tongue, a tumor type in which chromosome aberrations hitherto have not been reported. no less than 12 pseudodiploid clones were detected, giving the tumor karyotype 46,x,der(x)t(x;1)(q26;p32),der(1)(xqter----xq26::1p32 ----cen----1q42:), del(13)(q11q21),t(15;?) (q26;?)/46,xx,t(1;?)(p34;?),inv(2)(p21q11)/46,xx,t(1;10)(p32;q24)/ 46,xx, + der(1)(12pter----12p11::1p11----cen----1q32:: 11q13----11q22::1q32----1 ...20113162710
[ethical aspects of therapeutic borderline situations in intensive care]. 20113147854
microprocessor-controlled mixing system for rebreathing equilibration.a simple, economic, and accurate microprocessor system for the determination of mixed venous pco2 has been described. through the automatic gas mixing system, it is possible to facilitate the use of the rebreathing equilibration technique for the purpose of cardiac output calculations. it was also possible to flush the rebreathing bag within a brief time, providing the investigator with an automatic three-way valve driven by a solenoid.20113131062
[st segment analysis in 24-hour long-term ecg in patients with stable angina pectoris and angiographically detected coronary sclerosis].st-segment analysis on 24-hour holter ecg was performed in 64 patients with angiographically proven coronary artery disease, a positive exercise test and chronic stable angina. during 125 days of recording, 494 episodes of transient st-segment depression were observed, at an average of 4.0 +/- 3.7 episodes (1-13 episodes, median: 3 episodes) per day. the duration of st depression per episode was 13.2 +/- 14.4 min (1-90 min; median: 8 min). no episodes of st-elevation were observed. only 27 (5.5% ...20113122429
confirmatory tests for the dry eye of sjögren's syndrome.the diagnosis of moderate degrees of tear depletion is difficult using conventional tests such as the schirmer test, clinical evidence and even a confirmatory test such as the lysozyme test. we have refined the lysozyme test using quantitative techniques and calibrated standards. we found this satisfactory on a population basis, but not on an individual basis. we developed an elisa test for assaying five tear proteins 'lysozyme, lactoferrin, ceruloplasmin, iga and igg' which gives a much more ac ...20113473636
[economic efficacy of hygienic recommendations in regional planning]. 20113106168
modified in vivo platelet retention test for evaluating primary haemostasis.we present a modified in vivo platelet retention test for evaluating platelet plug formation in a standardized incision applied to the skin (template bleeding time). in contrast to previously published similar procedures we determined platelet retention at defined time intervals. the investigation of 20 healthy subjects with this method revealed a characteristic biphasic pattern of platelet consumption at the wound surface, which could be correlated with primary and secondary platelet aggregatio ...20113138871
an unusual manifestation of a common disease. 20113128564
staff surgery--the inevitable question.the results of a survey of 450 plastic surgeons regarding the practice of operating on their staff members is presented. an overwhelming majority (85 percent) of responding surgeons do operate on their staff. whether surgery is a "right" of employment or a "reward" for service was addressed. seventy-two percent felt surgery was a "reward," while only 8 percent felt it was a "right." the results found complications to be relatively minor but numerous (23.5 percent). the need for an office policy ...20113340684
pelvic endometriosis: a consequence of stress? 20113319400
cyclic nucleotide levels of the photosensitive irises of bufo marinus and lophius.the sphincter pupillae muscle of several species contracts autonomously after light directly strikes the iris. the response is initiated by isomerization of rhodopsin in the sarcolemma. light-induced release of ca2+ from internal stores is one step in the transduction process. the levels of cyclic amp and cyclic gmp were measured after irises were stimulated by light. stimulation by light does not produce measurable or consistent changes in the levels of either cyclic amp or cyclic gmp within th ...20113026826
detection and management of anatomic congenital anomalies. a new obstetric challenge.whereas once the obstetrician was primarily concerned with diseases affecting the mother, the scope of antenatal fetal care has expanded to include a broader range of fetal diseases such as growth disorders and congenital anomalies. the feasibility of identifying congenital anomalies before birth has created an entirely new field of obstetrics. the specialist is now expected to be informed about the differential diagnosis, pattern of inheritance, mechanism of disease, prognosis, optimal obstetri ...20113067165
[dementia screening by a short cognitive test]. 20113222054
international federation of clinical chemistry (ifcc) scientific committee: drug interferences and drug effects in clinical chemistry. part 5. laboratory tests during clinical trials. 20123598472
[hip joint development following simultaneous intertrochanteric varus rotation osteotomy and pemberton's pericapsular ilium osteotomy]. 20124062853
[hip joint development following simultaneous intertrochanteric varus rotation osteotomy and pemberton's pericapsular ilium osteotomy]. 20124062853
[use of dna-dna hybridization methods for studying the epidemiology and evolutionary similarity of drug resistance determinants].a procedure for rapid mass assay of clinical strains of microorganisms based on dna-dna hybridization was developed. epidemiology of the gentamicin resistance determinant cloned earlier from clinical strains of the same hospital was studied and its plasmid localization in representatives of various genera of enterobacteriaceae was confirmed. the studies on dot-hybridization showed that in three antibiotic-producing organisms, i.e. s. fradiae 918 producing neomycin, m. purpurea 1535 producing gen ...20123521468
captopril and hydrochlorothiazide: rationale for their combination.the results of controlled clinical studies have shown that about 80% of hypertensive patients have a satisfactory blood pressure reduction when treated with a combination of captopril and thiazide diuretics. the high response rate to this treatment can be explained on the basis of the mechanism of action of these drugs. in the long term, diuretics act by reducing peripheral vascular resistance. the mechanism by which they reduce peripheral vascular resistance is the subject of debate, but could ...20123555583
hla associations in an arab type 1 diabetic population.we have studied hla-a, -b, -c, -dr, and -dq antigen frequencies in 63 type 1 diabetic arab patients resident in kuwait. both hla-dr3 (relative risk (rr) = 5.80) and -dr4 (rr = 2.87) showed positive associations with type i diabetes mellitus in these patients whilst -dr2 (rr 0.16) and -dr5 (rr = 0.15) were negatively associated. the strong positive association with both hla-dr3 and -dr4 was confirmed in non-gulf arabs (rr = 12.55 and 4.29, respectively) whereas the gulf arabs had a significant po ...20123502987
a new approach to medical malpractice insurance. tort system could be bypassed by no-fault insurance or a contractural arrangement. 20123457420
predictability of maxillary surgery: a comparison of internal and external reference marks.internal reference lines have traditionally been used to correlate model work with maxillary surgery. an external point of reference has been suggested for more accurate positioning of the maxilla during surgery. this study compared the predictability of two groups of patients undergoing le fort i maxillary osteotomies with either internal reference lines or an external reference point. in the group in which an external reference point was employed, the position of the maxillary central incisor ...20123459981
[x-ray computed tomography in the course of mediastinitis after sternostomy for heart surgery].results are reported of a prospective study of 79 ct scan examinations in 50 patients who had undergone sternotomy for cardiovascular surgery. in 69 cases the examination was conducted during the course of a progressive postoperative mediastinitis treated surgically. mediastinitis was confirmed in 13 cases, including 12 relapses. in 2 cases the ct scan image was normal (2 false negatives) whereas mediastinal drains had been inserted. the ct scan image of mediastinitis shows mainly hypodense flui ...20123585856
clean intermittent self-catheterisation in the elderly.the results of teaching the technique of clean intermittent self-catheterisation (cisc) to 20 elderly patients (aged 65-81 years) are reported. the patients were followed up for a maximum of 4 years. the use of this technique in the management of selected elderly patients with lower urinary tract dysfunction is discussed.20123664201
treatment of progressive chronic renal failure. implications for changing the composition of amino acid and ketoacid supplements. 20123549153
treatment of progressive chronic renal failure. implications for changing the composition of amino acid and ketoacid supplements. 20123549153
syphilitic aneurysm of the descending thoracic aorta with radicular pain. 20123962756
the abraham flexner award for distinguished service to medical education. john a. d. cooper, m.d. 20123511261
databases in molecular biology: a codata task group at work.a certain concern exists that the exponential growth of nucleic acid and protein sequence data will saturate the channels of data acquisition, distribution and utilization on the one hand and, on the other hand, that even the actual resources are still not fully and easily accessible to any bench scientist. despite the stake of the scientific community at large in the fundamental data collected in this field, there has been in past years only a modest effort to discuss the common problems at an ...20123447161
getting started on diabetic care. 20123505343
predicted time of dialysis in patients with different volumes of urea distribution--the use of mathematical model. 20123447442
plasma thyrotrophin and its response to thyrotrophin releasing hormone in endemic goitre. 20124203696
[on the topical use of a new steroid, formocortal, in the treatment of phlebodermitis and in cutaneous auto- and homo-grafts]. 20124942789
[dynamic study of the excretion of urinary fluoride induced by fluoridated tooth paste]. 20123463490
[you make the diagnosis. cerebral gigantism (sotos syndrome)]. 20123405613
how companies can ease the burden of aids at work. 20123405574
[examination and emergency treatment of acute diplopia]. 20123580671
chronic glomerulonephritis with massive iga deposits.a total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. a group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin a found by immunofluorescent examination, has been separated on the basis of immunohistochemical studies. in this group, occurrence of different morphological forms of glomerulonephritis has been observed: 30.4% mesangial-proliferative glomerulonephri ...20124086240
chronic glomerulonephritis with massive iga deposits.a total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. a group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin a found by immunofluorescent examination, has been separated on the basis of immunohistochemical studies. in this group, occurrence of different morphological forms of glomerulonephritis has been observed: 30.4% mesangial-proliferative glomerulonephri ...20124086240
the response of caries-free, unfilled teeth to electrical excitation: a comparison of two new pulp testers. 20123462155
low risk of vertebral fracture in mexican american women.ethnicity is important in assessing risk for osteoporotic fractures, and should be considered in decision-making about the use of prophylactic treatments. few data are available, however, on fracture risks among hispanic patients. to assess the risk of vertebral fracture in mexican americans, we determined the prevalence of vertebral fracture among 822 patients, aged 15 to 86 years, who underwent spinal roentgenography in a study of low-back pain. after adjusting for age, use of steroids, drug o ...20123498450
blow-blow-blow. 20123379717
pharmacokinetics of fentanyl in the elderly.the pharmacokinetics of fentanyl were determined in seven elderly (71-82 yr) and seven younger adults (18-41 yr) anaesthetized with thiopentone, nitrous oxide in oxygen and morphine. fentanyl was administered as a 2-min i.v. infusion at doses of 15 micrograms kg-1 for elderly patients and 20 micrograms kg-1 for the younger patients. plasma samples were obtained for 4 h and fentanyl concentrations determined by radioimmunoassay. fentanyl concentration, per microgram kg-1 administered, was higher ...20123377944
diagnosis of right ventricular involvement in chronic inferior myocardial infarction by means of body surface qrs changes.st segment elevation in right precordial leads is thought to be good predictor of right ventricular involvement in patients with acute inferior myocardial infarction. this view, however, is rapidly disappearing. therefore, using qrs changes in body surface potential maps in the chronic phase, we have attempted to differentiate patients with or without right ventricular involvement. thirty patients with chronic inferior myocardial infarction (2 or more months after onset) were studied, in whom 87 ...20123370768
fenbutatin oxide and chlorfenvinphos effects on the entomophagous arthropod fauna of citrus. 20123580598
the diabetic school child. 20123347151
[pathogenesis of disseminated candidiasis in heroin addicts]. 20123347123
mixed islet-lymphocyte culture as a model for pancreatic islet immunogenicity and cell-mediated immune injury. 20123314039
epidemiology of allergic contact sensitization. 20123316993
viral infections and asthma. 20123318571
cleft lip and palate. the state of the art. 20123333463
[demonstration of anti-laminin antibodies in the serum of healthy subjects].antibodies directed against laminin, a glycoprotein of basement membranes, have been sought for in the sera of 347 healthy subjects by a method relying on the agglutination of laminin-coated latex particles. fifty-five subjects (15.9%) hae been found to be positive, 37 with a titre of 2, 14 with a titre of 4 and 4 with a titer of 8. applied to 106 patients whose a renal biopsy had been examined by immunofluorescence, the test yielded positive results in 91% of patients with linear deposits as co ...20123304440
[a century of publishing activity in the morphological sciences]. 20123317672
[properties of lak cell activity and lak-generation in pbl isolated from patients with renal cell carcinoma]. 20123266646
[treatment of trigeminal neuralgia (review)]. 20123296586
[ercp in children]. 20123269128
inappropriate use of casualty departments. 20123256693
dental anxiety and dmfs status: association within a us naval population versus differences between groups.measurement of dental treatment anxiety and oral health, in a sample of naval recruits, confirmed the generally held expectation that a high anxiety group would have significantly greater numbers of diseased surfaces (ds) than a low anxiety group. however, it was also shown that dental anxiety was not a predictor of ds within the ungrouped sample. in evaluating the public health impact of dental treatment anxiety on oral health, attention must be paid to the context of data collection and analys ...20133857152
[value of the cardiothoracic index in the evaluation of cardiac performance in dilated cardiomyopathies]. 20133838062
[schizophrenia and drug therapy]. 20133837887
extrachromosomal dna transformation of caenorhabditis elegans.dna was introduced into the germ line of the nematode caenorhabditis elegans by microinjection. approximately 10% of the injected worms gave rise to transformed progeny. upon injection, supercoiled molecules formed a high-molecular-weight array predominantly composed of tandem repeats of the injected sequence. injected linear molecules formed both tandem and inverted repeats as if they had ligated to each other. no worm dna sequences were required in the injected plasmid for the formation of the ...20133837845
transhepatic obliteration of esophageal varices using stainless coils combined with hypertonic glucose and gelfoam.a total of 63 patients with variceal bleeding were included in this study. fifty-six attempts at percutaneous transhepatic variceal obliteration were made using stainless steel coils followed by 50% glucose and gelfoam in 27 emergency cases, in whom bleeding did not stop by conventional medical treatment; and in 18 elective cases, in whom bleeding did stop by conventional medical treatment. the remaining 18 patients, whose bleeding was controlled by conventional medical treatment, were used as a ...20133874897
transhepatic obliteration of esophageal varices using stainless coils combined with hypertonic glucose and gelfoam.a total of 63 patients with variceal bleeding were included in this study. fifty-six attempts at percutaneous transhepatic variceal obliteration were made using stainless steel coils followed by 50% glucose and gelfoam in 27 emergency cases, in whom bleeding did not stop by conventional medical treatment; and in 18 elective cases, in whom bleeding did stop by conventional medical treatment. the remaining 18 patients, whose bleeding was controlled by conventional medical treatment, were used as a ...20133874897
[postoperative functional results in oral and oropharyngeal tumors].the functional results of surgery for intraoral tumours were evaluated in a retrospective study. among the many reconstructive techniques there is a place for healing by secondary intention or for primary closure of the defect. bony reconstruction after lateral mandibulectomy may be omitted. the determining factors for good postoperative results were motivation, functional deglutition and speech exercises.20133997575
[postoperative functional results in oral and oropharyngeal tumors].the functional results of surgery for intraoral tumours were evaluated in a retrospective study. among the many reconstructive techniques there is a place for healing by secondary intention or for primary closure of the defect. bony reconstruction after lateral mandibulectomy may be omitted. the determining factors for good postoperative results were motivation, functional deglutition and speech exercises.20133997575
[hepatitis b in dental practice]. 20133870241
secondary correction of the cleft lip and nose deformity: a new technique for revision of whistling deformity.reconstruction of the continuity of the orbicularis oris is the main component in correction of the whistling deformity. however, many of the cases are associated with other deformities, such as conspicuous lip scars, an unnaturally wide central lip, flaring alae with wide nostril floors, and a short columella with a flat nasal tip. we report a technique that combines correction of such deformities with reconstruction of the orbicularis oris in a single operation.20133863728
intra-articular reconstruction of the anterior cruciate ligament.in this article, the author provides criteria for the recommendation of surgical intervention in acute and chronic anterior cruciate ligament insufficiency and describes various intra-articular procedures for both conditions. intra-articular reconstruction of the anterior cruciate ligament with a vascularized patellar tendon graft is described in detail, as are the excellent results achieved with this procedure over the past 8 years.20133889767
psychophysiological treatment of facial pain syndromes. 20133889741
[intraventricular meningitis as a complication of purulent meningitis. a case report].report of a case of intraventricular hematoma as purulent meningitis complication in a child of 6 months old, without vascular malformation. the evolution was satisfactory after the surgical treatment.20133833145
screening for breast cancer in apparently well women. 20134015527
caries incidence among cerebral-palsied children. 20134388032
[nursing of patients with cervical and other spinal cord injuries for independent urination actions: description of the nursing processes]. 20133848515
a rare case of carpal tunnel syndrome due to tenosynovial osteochondroma.a rare case of carpal tunnel syndrome due to an extra-articular synovial osteochondroma arising from the synovial sheath of the flexor pollicis longus tendon, is described. this has not been described in the literature previously. the cyst with the contained osteochondroma was excised with good relief of symptoms. the histological examination of the osteochondroma revealed another interesting and unusual feature. we would like to document a case of tenosynovial chondrometaplasia of the synovial ...20133794505
[what a diabetic patient must know]. 20133846682
an introduction to physical assessment for the nephrology nurse. 20133846448
[educational development of so-called problem children]. 20133751740
[a case of extensive hemangioma of the hypertrophic auricle]. 20133751064
eye infections encountered by the pediatrician. 20133797318
[surgery of myomas during pregnancy and labor]. 20133719754
[the launching of bicarbonate dialysis in pilsen]. 20133719624
cross-bridge free skin flap transfer: case report.the authors present a procedure that can be used in cases of massive skin and soft tissue defect accompanied by extensive vascular injury. the technique involves the use of two donor components (a free skin flap and a vascular donor) which form a single unit postoperatively. the free flap is stretched over crossed limbs, with its major lateral portion serving to cover the defect, and the margin of its medial portion containing the flap pedicle sutured to a pedicled skin flap from the healthy con ...20134057171
[the empty delta sign. a useful or misleading sign in cerebral x-ray computed tomography?].one case of bifidity of the superior sagittal sinus, resulting in a false "empty delta sign", is presented. the authors emphasize the importance of the indirect signs of sinovenous thrombosis, i.e. cerebral edema and multiple or bilateral hemorrhagic infarcts, in the diagnosis of true empty delta sign.20133701671
thermal properties of water in myoglobin crystals and solutions at subzero temperatures.the water of hydration in myoglobin crystals and solutions was studied at subzero temperatures by calorimetry and infrared spectroscopy (ir). for comparison we also investigated glycine, dl-alanine and dl-valine solutions. the hydration water remains amorphous at low temperatures. we find a broad glass transition between 180 and 270 k depending on the degree of hydration. the ice component shows a noncolligative melting point depression that is attributed to a finite conformational flexibility. ...20133741983
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