| enterotoxin-producing bacteria and parasites in stools of ethiopian children with diarrhoeal disease. | enterotoxinogenic bacteria were isolated from 131 (37%) of 354 ethiopian infants and children with acute gastrointestinal symptoms. only one of these isolates belonged to the classical enteropathogenic serotypes of esch. coli. two colonies from each patient were isolated and tested for production of enterotoxin by the rabbit ileal loop test, the rabbit skin test, and an adrenal cell assay. however, only 38% of the isolated enterotoxinogenic strains were esch. coli; the others belonged to klebsie ... | 1976 | 1008593 |
| klebsiella aerogenes in mares. | | 1976 | 1014302 |
| [microbiological and cytological aspects of the aspirate bronchoscopy (author's transl)]. | the authors compare by microbiological and cytological aspect the result got by sputum and aspirate at bronchoscopy. they point out that aspirate at bronchoscopy permits a more significant etiological diagnosis by both microbiological or cytological point of view. | 1976 | 1015866 |
| the role of energy-spilling reactions in the growth of klebsiella aerogenes nctc 418 in aerobic chemostat culture. | when cell-saturating amounts of glucose and phosphate were added to steady state cultures of klebsiella aerogenes that were, respectively, glucose- and phosphate-limited, the organisms responded immediately with an increased oxygen consumption rate. this suggested that in neither case was glucose transport the rate-limiting process, and also that organisms must possess effective mechanisms for spilling the excess energy initially generated when a growth-limitation is temporarily relieved. steady ... | 1976 | 1015953 |
| concentrations of cefazolin in human skeletal muscle. | tissue concentrations of cefazolin were measured in 18 patients undergoing urological operations. specimens of skeletal muscle and blood were taken simultaneously at predetermined intervals. the concentrations in serum and homogenized skeletal muscle were determined by means of the agar well diffusion method. a comparison of standard curves obtained with phosphate buffer solution and the supernatant of muscle homogenate revealed no substantial binding of cefazolin to the supernatant of muscle ho ... | 1976 | 1017877 |
| [the patient as a source of bacteria in intensive care units: influence of antibiotics and tracheal intubation (author's transl)]. | 133 patients in an intensive care unit, who prior to admission had not shown any signs of bacterial infection and had not received antibiotic treatment, were assigned to two groups at random. one group received antibiotic prophylaxis with penicillins or cephalosporins (+pat.), the other group did not receive antibiotics (-pat.). staph. aureus was the most frequent facultative pathogen in tracheal secretions and in the environment of "-pat.". this organism was significantly more frequent in "-pat ... | 1976 | 1017879 |
| [indices of bacterial contamination and natural resistance in wistar line laboratory rats]. | conventional laboratory rats of wistar line are contaminated with bacterial flora. the predominating bacteria in the intestine were the rod-like forms, while in the mouth cavity and vagina predominated the coccal forms. the contamination level of the cavities and penetration of the contaminants into the internal organs depended on the state of the host natural resistance. | 1976 | 1020946 |
| taxonomical relationships klebsiella-enterobacter investigated by means of phage-bacteria systems. | | 1976 | 1021043 |
| the problem of infections in acute leukemias. personal experience in diagnosis and treatment. | this report is based on experience over the last 5 years in the diagnosis and treatment of infections in 200 acute leukemic patients hospitalized in the institute of haematology, university of rome. the relevant clinical and laboratory findings are discussed in relation to the diagnosis of secondary infections. most of the febrile episodes were associated with infection. the frequently rapid development of the infections in these patients requires empirical antibiotic treatment. the best results ... | 1976 | 1025649 |
| amikacin (bbk8) in infections due to gram-negative organisms in children over the age of one month. | thirty children over the age of one month were treated with amikacin (bbk8), a new aminoglycoside derived from kanamycin a, with three intramuscular dosage schedules. each group consisted of ten patients. the first received 7-5 mg/kg/12 hours, the second 7-5 mg/kg/24 hours and the third, 3-75 mg/kg/12 hours. the infections and the bacteria were similar in all three groups: pyelonephritis, abscesses of soft tissues, infected wounds, septicaemia, superinfected empyema, gastro-enteritis, chronic ot ... | 1976 | 1026522 |
| pneumonia syndromes in children. | | 1976 | 1027699 |
| inhibition of adp-induced platelet aggregation as a possible test for evaluation of the enterotoxigenicity of some enterobacteria. preliminary study]. | some culture filtrates or enterotoxin preparations from enterobacteria that activate the adenylate cyclase system (vibrio cholerae, lt fraction from escherichia coli and klebsiella pneumoniae, shigella dysenteriae type 1) exibit an inhibiting effect on adp-induced platelet aggregation, while other enterotoxin preparations not effective on adenylate cyclase system, don't interfere with this model. the a. propose the platelet aggregation as cellular assay to detect enterotoxin fractions effective ... | 1976 | 1028645 |
| [vocal and laryngo-tracheal sequelae of prolonged intubation at the university medical clinic of the cantonal hospital at lausanne]. | 70 patients (39 men and 31 women) submitted to a prolonged intubation at the centre respiratoire de la clinique médicale universitaire de lausanne have been investigated. they represent the half of the patients having survived of 488 cases treated between january 1966 and june 1974. 33% of the investigated patients (i.e. 18% of all men and 48% of all females) complain about a permanent dysphonia related to the intubation. 17% of the patients (i.e. 13% of all men and 23% of all females) presented ... | 1976 | 1034272 |
| [microbial maps and blood cultures in acute leukemia]. | microbial maps were performed taking swabs from nose, pharinx, external auditory meatus, groin, vagina, sputum and urine cultures in 69 cases of acute leukaemia, in order: to assess the germs' incidence in an "open ward" department; to eliminate the most dangerous pathogens with local treatment or with a selective therapy without broad-specturm antibiotics; to check, in the 43 cases followed from onset, the changes occurring during the admission and the disease progression; to collect data for c ... | 1976 | 1035410 |
| rhinoscleroma: a scanning electron-microscopic study. | nasal biopsies from 6 patients with rhinoscleroma were studied by scanning electron microscopy. numerous bacilli of different sizes were found on the epithelial surface. few bacilli with thin spiral terminal cilia were seen over the surface of large protruding non-epithelial cells. these cells appeared to be the mikulicz cells migrating from the tunica propria to the epithelial surface through small ulcerations. in the tunica propria, mikulicz cells containing numerous bacilli were observed. in ... | 1976 | 1035417 |
| cefamandole: antimicrobial activity in vitro of a new cephalosporin. | cefamandole, a new cephalosporin derivative, was found to have a broad spectrum of activity against a cross-section of both gram-positive and gram-negative bacteria isolated from clinical material. gram-positive cocci, except for streptococcus faecalis, were very susceptible. penicillin g-resistant staphylococcus aureus also was susceptible to cefamandole. minimal bactericidal concentrations for gram-positive cocci approximated the minimal inhibitory concentrations. strains of haemophilus influe ... | 1975 | 1044248 |
| pc-904, a novel broad-spectrum semisynthetic penicillin with marked antipseudomonal activity: microbiological evaluation. | pc-904, sodium 6-{d(-)-alpha-(4-hydroxy-1,5-naphthyridine-3-carboxamido) phenylacetamido}-penicillanate, is a novel semisynthetic penicillin derivative that possesses a broad spectrum of in vitro and in vivo antibacterial activities. in low concentrations, pc-904 inhibits growth against large proportions of the gram-positive and gram-negative organisms susceptible to carbenicillin and gentamicin. in addition, pc-904 is several times more potent than carbenicillin against organisms such as pseudo ... | 1976 | 1046355 |
| letter: klebsiella infections. | | 1975 | 1057099 |
| visualization of actin fibers associated with the cell membrane in amoebae of dictyostelium discoideum. | amoebae of dictyostelium discoideum were attached to a surface coated with polylysine, and the upper portion of the cells was sheared off with a stream of buffer. scanning and transmission electron microscopy showed that the cytoplasmic surface of the exposed membrane was covered with fibers consisting of actin-containing filaments. the actin was identified by its solubility properties and its ability to interact with muscle myosin. | 1975 | 1057168 |
| fever in acute myelogenous leukemia. | implications and course of fever were evaluated during hospitalization of 24 patients with acute myelogenous leukemia. forty-five febrile episodes were identified. fever present at admission was usually associated with a diagnosable and treatable infection; fever shortly after induction was self-limited; and fever during granulocytopenia was more likely to be associated with bacteremia. bacteremia and pneumonia were the most common types of infection. only gram-negative bacteria and candida were ... | 1975 | 1057870 |
| temporomandibular ankylosis secondary to rheumatoid arthritis. report of a case. | a case of unilateral bony ankylosis of the temporomandibular joint secondary to rheumatoid arthritis is presented, and the surgical treatment and postoperative regime are suggested. it is believed that, with proper motivation of the patient, an adequate oral opening may be maintained. | 1975 | 1059058 |
| isolation of subunits of citrate lyase and characterization of their function in the enzyme complex. | citrate lyase [ec 4.1.3.6; citrate oxaloacetate-lyase (pro-3s-ch2-coo--leads to acetate)] from klebsiella aerogenes has been dissociated with urea; the three different subunits, alpha-chain (molecular weight congruent to 54,000), beta-chain (molecular weight congruent to 32,000), and gamma-chain (acyl carrier protein; molecular weight congruent to 10,000), have been isolated in pure and catalytically active state. recombination of the three subunits produced citrate lyase that was indistinguisha ... | 1975 | 1060145 |
| recent observations concerning klebsiella infections in stallions. | a high incidence of klebsiella contamination in german 'warmblut' and thoroughbred stallions is reported. the organism was recovered from the nostrils, prepuce, pre-ejacultory secretion and, in some cases, on the body surface, in the faeces and on the ground of the covering (mating) yard. fertility was not affected. however, differences of virulence were observed and type 5 proved to be the most pathogenic. | 1975 | 1060768 |
| the rapid differentiation of the klebsiella-entero-bacter-serratia from other enterobacteriaceae on esculin-agar. | | 1975 | 1062501 |
| causes of death in adults with acute leukemia. | the causes of death were investigated in 315 adults with acute leukemia during a 7-year period (1966-1972). infection alone or in combination was the most common cause (75%), followed by hemorrhage (24%) and organ failure (9%). most of the infections were either systemic or pulmonary. seventy-five percent of the systemic infections and 72% of the pneumonias were caused by bacteria. klebsiella pneumoniae, escherichia coli and pseudomonas aeruginosa were the most frequent organisms isolated. after ... | 1976 | 1063911 |
| chloramphenicol today. | | 1975 | 1079882 |
| endogenous candida endophthalmitis leading to bilateral corneal perforation. | a premature neonate developed advanced bilateral endophthalmitis before the significance of underlying candida sepsis was appreciated. severe endophthalmitis resulted in corneal thinning, descemetocele formation, and perforation. the infection occurred in the clinical setting of broad-spectrum antibiotic therapy and indwelling intravenous catheters. cultures of blood and catheter tips had been positive for candida but were not considered significant until advanced ocular infection was noted. the ... | 1975 | 1081343 |
| total excision of the sternum and thoracic pedicle transposition of the greater omentum; useful strategems in managing severe mediastinal infection following open heart surgery. | mediastinal sepsis following open heart surgery is a significant cause of death. open drainage of the mediastinumalone was employed originally in management of this problem. more recently, debridement, drainage, and reclosure have been used. various irrigation solutions, such as antibiotics and betadine, have been advocated to control severe mediastinal sepsis. three principles of management in patients unresponsiveness to the above techniques have proved successful in two patients with life-thr ... | 1976 | 1085994 |
| amikacin in the treatment of gram-negative bronchopulmonary infections. | six patients with acute gram-negative bronchopulmonary infection were treated with amikacin (15 mg/kg per day) administered intramuscularly in two equal doses at 12-hr intervals for 10-13 days. two patients had underlying nonspecific pulmonary disease, two had advanced bronchocarcinoma, and two had extensive bronchiectasis (due to chronic aspergillosis in one patient). the pathogens were pseudomonas aeruginosa in three patients, and haemophilus influenzae, klebsiella ozaenae, and enterobacter cl ... | 1976 | 1086876 |
| disseminated strongyloides stercoralis. a complication of immunosuppression. | | 1975 | 1088964 |
| massive pulmonary gangrene: a severe complication of klebsiella pneumonia. | summary: massive pulmonary gangrene developed in two patients. review of the literature reveals 10 other case reports of pulmonary gangrene complicating lobar pneumonia. among the total of 12 patients whose cases have now been reported, all 4 patients who were treated nonsurgically died and the 8 who underwent surgical resection of the gangrenous lung survived. the present report emphasizes the necessity of early recognition and appropriate surgical treatment for a successful outcome. | 1975 | 1089466 |
| the management of rhinoscleroma. | this investigation showed that the organism klebsiella rhinoscleromatis was present consistently in our cases. it was found to be difficult to eradicate completely although seemingly sensitive to common antibiotics in vitro. a prolonged treatment with bactericidal antibiotics is therefore necessary to eradicate it. nasal dilatation rather than excision of granulations is required to restore nearly-normal physiological nasal function. excision or cautery of granulations inside the nose is discour ... | 1975 | 1089741 |
| determining antibiotic levels in the blood. | methods for the rapid determination of antibiotic blood levels require particular organisms or special conditions or long incubation. a method was developed for the rapid determination of antibiotic blood levels which requires no special equipment and is rapid. special stains are not required. utilizing bacteria from standard kirby-bauer sensitivity plates, a suspension is prepared and a pour plate made. organisms which are sensitive to the questioned antibiotic and resistant to other antibiotic ... | 1975 | 1090163 |
| effect of exposure to hyperoxic, hypobaric, and hyperbaric environments on concentrations of selected and aerobic and anaerobic fecal flora of mice. | alterations in selected aerobic and anaerobic fecal microflora of the mouse were determined during exposure to hyperoxic and normoxic hypo- and hyperbaric environments. examination of fecal cultures obtained during exposure for 6 weeks to either 60 or 77% oxygen concentration 1 atmosphere absolute revealed little alteration in the aerobic or anaerobic flora. there appeared to be only a retardation in the reduction of the klebsiella-enterobacter flora which normally occurs after weaning. during e ... | 1975 | 1090255 |
| bacterial survival in laundered fabrics. | bacterial survival was determined in linens (i) inoculated with staphylococcus auerus (ii), taken from hospital isolation patients' beds, and (iii) used by students in their homes. two different washers using temperatures of 38, 49, 54 and 60 c, respectively, for different times were empolyed along with a commercial tumbler dryer. findings, after macerating the linens in waring blender and enumerating on nonselective media, indicate that acceptable levels of survivors can be acheived in motel an ... | 1975 | 1090256 |
| biochemistry and genetics of klebsiella pneumoniae mutant strains unable to fix n2. | selected mutant strains of klebsiella pneumoniae that are unable to fix nitrogen have been characterized according to nitrogenase component activity as well as antigenic cross-reacting material. the lesions in these strains have been mapped by transduction, and the results indicate that there are at least five genes specifically responsible for nitrogen fixation in vivo. besides genes that specify the structure of the two nitrogenase components, there is a gene for a factor that is required for ... | 1975 | 1090602 |
| occurrence of the bacteriophage lambda receptor in some enterobacteriaceae. | in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ... | 1975 | 1090748 |
| scrotal gangrene treated with oxygen under high pressure. | | 1975 | 1090761 |
| [antibiotics in newborns and young infants]. | localized and generalized infections in newborns nowadays are mostly due to gram negative bacteria (e. coli, klebsiella, enterobacter, pseudomonas pyocyanea, serratia marcescens et al.). unspecific treatment causes an increasing rate of resistance, as shown by an account of our own experiences. tobramycin, gentamycin, and cefazolin appear to be particularly promising antibiotics to avoid the development of resistance though their pharmacokinetics in the newborn have to be considered carefully. b ... | 1975 | 1090810 |
| microbial production of ammonium ion from nitrogen. | genetic manipulation of nitrogenase and key glutamate-forming enzymes can provide mutants that excrete fixed n2 as nh4+. a derepressed n2 fxation mutant (sk-24) has been isolated , which excretes up to 20.2 mumol of fixed n2 as nh4+ per mg of cell protein in 24 hr at room temperature. biochemical analysis shows that this mutant, which requires glutamate for growth, releases fixed n2 as nh4+ into the environment because of (i) constitutive synthesis of nitrogenase and (ii) genetic blocks resultin ... | 1975 | 1090930 |
| composition of the citrate lyase acyl carrier protein from klebsiella aerogenes. | | 1975 | 1091504 |
| enterotoxigenic intestinal bacteria in tropical sprue. ii. effect of the bacteria and their enterotoxins on intestinal structure. | | 1975 | 1091526 |
| titres and cross reactions of commercial antisera for the capsular typing of klebsiella species. | ninety commercially supplied sera for the capsular typing of klebsiella species were tested in a full chequerboard against 72 type strains. only four of 144 homologous reactions could not be detected. of the 6336 possible heterologous reactions, 91 actual cross reactions were found. all positive reactions were titrated and working dilutions deduced. this provides essential information for the successful typing of unknown strains with these sera. | 1975 | 1091662 |
| chemistry of cephalosporin antibiotics. 30. 3-methoxy- and 3-halo-3-cephems. | the exo-methylene group in esters of 7-acylamido- and 7-amino-3-methylenecephams was ozonized to give 3-hydroxy-3-cephems. conditions are described to effect a selective n-acylation of a 3-hydroxy-3-cephem nucleus ester. vilsmeier reagents converted 7-acylamido-3-hydroxy compounds to 3-halo-3-cephem derivatives. diazomethane converted the 3-hydroxy compounds to 3-methoxy-3-cephem derivatives. removal of the ester-protecting group at the c4-carboxyl afforded a select group of cephalosporins with ... | 1975 | 1091736 |
| differentiation of klebsiella-enterobacter-serratia organisms. | differentiation of 625 stains of bacteria which fulfilled the requirements laid down for the definition of the tribe klebsielleae was carried out using 6 biochemical tests. five hundred and forty-six strains were identified as members of the genus klebsiella, 46 of the genus enterobacter and 33 of the genus serratia. | 1975 | 1091989 |
| [work organization for the control of bacterial mastitis among large herds of dairy cows]. | | 1975 | 1092051 |
| jejunal microflora in malnourished gambian children. | growth of bacteria greater than 10-5 organisms/ml was found in 22 children, of whom 17 gave a histroy of chronic diarrhoea. the other 8 children had either no diarrhoea or where having an acute attack lasting for a few days. in those with chronic diarrhoea, esch. coli, bacteroides, and enterococci tended to occur more frequently, whereas streptococci occurred more frequently in those with acute diarrhoea. bacilli, staphylococci, micrococci, klebsiellas, pseudomonads, and candidas often occurred ... | 1975 | 1092272 |
| disinfection of anaesthesia equipment by a mechanized pasteurization method. | | 1975 | 1092435 |
| the diffusion and concentration of trimethoprim in human vaginal fluid. | colonization of the vaginal introitus with enterobacteriaceae was cleared dramatically in women receiving trimethoprim-sulfamethoxazole for recurrent urinary tract infections. vaginal fluid was collected from seven women; five of the seven had two vaginal fluid collections each while on full-dose therapy (total, 10 samples), and five had two or more collections each while on prophylactic, low-dose therapy (total, 14 samples). bactericidal concentrations of trimethoprim were found in all samples ... | 1975 | 1092766 |
| transient bacteremia associated with percutaneous liver biopsy. | transient bacteremia associated with percutaneous liver biopsy was studied by pour-plate blood cultures, which were obtained immediately before and after the procedure and 5, 10, 15, and 30 min later in 89 patients. part of the liver tissue was also cultured in all patients. histological diagnoses included hepatitis, cirrhosis, cholangitis, fatty liver, granulomata, metastatic liver disease, lymphoma, and miscellaneous disorders. all blood cultures obtained before liver biopsy were sterile. bact ... | 1975 | 1092772 |
| nosocomial infection caused by gentamicin-resistant, streptomycin-sensitive klebsiella. | resistance to gentamicin increased abruptly among nosocomial isolates of klebsiella and enterobacter at the new york veterans administration hospital in 1973 and 1974. a prospective clinical survey revealed a greater incidence of true infection caused by klebsiella than by enterobacter. the initial site of implantation was usually the urinary tract. multiple serotypes were involved, and one of these was found in rectal swabs of patients treated with antibiotics. gentamicin resistance declined ra ... | 1975 | 1092773 |
| hand infections secondary to human bites. | | 1975 | 1092876 |
| [on flucloxacillin sensitivity determination by the disc method (author's transl)]. | | 1975 | 1092891 |
| nonclostridial crepitant cellulitis due to klebsiella. | | 1975 | 1092996 |
| the mutagenic action of nitroimidazoles. ii. effects of 2-nitroimidazoles. | the 2-nitroimidazoles ro-71051 (n-benzyl-2-nitro-1-imidazole-acetamide) and ro-5-9963 (3(2-nitro-1-imidazolyl)-1,2-propanediol) increased the mutation rate of a klebsiella pneumoniae mutant to streptomycin-resistance including streptomycin-dependence in luria and delbruck's fluctuation test in concentrations of 0.05-1 mm and 0.02-0.2 mm respectively. the 2-nitroimidazole, azomycin, (ro-5-9129/001) failed to increase the mutation rate. the results are compared to those obtained with the 5-nitroim ... | 1975 | 1093016 |
| [klebsiella septicemia. epidemiologic aspects based on antigenic and biochemical studies of strains]. | 50 strains of klebsiella pneumoniae were isolated by blood cultures at brugmann hospital (brussels) between 1967 and 1971. the biochemical and antigenic characteristics of the strains and their sensitivity to antibiotics were determined for epidemiological purposes. with the exception of the strains found in an hemodialysis unit, where the study showed the existence of an epidemic focus caused by serotype 28 biotype d, the strains consisted of a large number of capsular serotypes and of biotypes ... | 1975 | 1093105 |
| treatment of chronic prostatitis. comparison of minocycline and doxycycline. | the results of minocycline and doxycycline therapy in 41 patients with chronic prostatitis and minocycline therapy in 6 patients with acute prostatitis were evaluated. in the comparative study of chronic prostatitis, minocycline and doxycycline were given on the same dosage schedule, milligram for milligram: a loading dose of 200 mg. followed by 100 mg. twicd daily. over-all clinical responses to therapy with either agent were generally satisfactory, and no statistically significant difference ... | 1975 | 1093309 |
| escherichia coli serogroups in breast-fed and bottle-fed infants. | 1) eighty-seven breast-fed and 95 bottle-fed infants were examined for differences in escherichia coli serogroup pattern. 2) the serogroup composition was less complex in breast-fed infants. fewer serogroups were found in the individual breast-fed child. however, with few exceptions, the same o groups were found in the two groups of infants. the prevalent o groups were among those also found most frequently in faeces from adults. 06 strains were more common in the breast-fed group, while 07 and ... | 1975 | 1093353 |
| transient bacteremia associated with barium enema. | a group of 175 patients had barium enema. pour-plate blood cultures were obtained immediately before and after the procedure and 5, 10, 15, and 30 minutes later. bacteremia was demonstrable in 20 (11.4%) patients. in some, blood cultures were positive for as long as 15 minutes after barium enema; all were negative at 30 minutes. among the bacteria associated with the 20 episodes of bacteremia were escherichia coli, klebsiella, enterococci, proteus morganii, bacteroides, and veillonella. the inci ... | 1975 | 1093504 |
| studies on the control of coliform mastitis in dairy cows. | | 1975 | 1093639 |
| trimethoprim-resistant enterobacteriaceae in urinary tract infection. | the incidence of trimethoprim-resistant enterobacteriaceae has not increased since the introduction of the combination trimethoprim-sulfamethoxazole (tmp-smx) into the clinical use at our centre in 1973. using the minimum inhibitory concentration (mic) as the index of trimethoprim resistance, this ranged from 1.6 to 800 mug/ml; for the majority of isolates it lay between 1.6 and 12.5 mug/ml. about half of these trimethoprim-resistant organisms were sensitive to sulfonamide. in vitro data suggest ... | 1975 | 1093652 |
| a comparison of trimethorprim-sulfamethoxazole with sulfamethoxazole alone in infections localized to the kidneys. | ninety patients with urinary tract infections were treated in a randomized double-blind study with either a combination of trimethoprim and sulfamethoxazole (tmp-smx) or sulfamethoxazole alone (smx). thirty of 42 patients treated with tmp-smx were cured by the time of follow-up compared with 26 of 48 treated with smx alone. of the 29 patients infected with smx-resistent organisms, the combination tmp-smx cured 12 of 17, whereas smx alone cured 2 of 12. of the 61 patients infected with smx-sensit ... | 1975 | 1093658 |
| reversible inactivation of the isocitrate dehydrogenase of escherichia coli ml308 during growth on acetate. | during aerobic growth of escherichia coli ml308 on acetate as sole carbon source, the apparent synthesis of isocitrate dehydrogenase was repressed relative to cultures on other carbon sources, such as glucose, which do not employ the glyoxylate bypass as an anaplerotic sequence. when cells were removed from an acetate medium, or when compounds were added which made the operation of the glyoxylate bypass unnecessary, the activity of isocitrate dehydrogenase rapidly increased 3- to 4-fold but fell ... | 1975 | 1094097 |
| ion-exchange chromatography of streptothricin-like antibiotics. | | 1975 | 1094234 |
| ion-exchange chromatography of aminoglycoside antibodies. | | 1975 | 1094235 |
| klebsiella urinary tract infection. | the klebsiella species form a heterogeneous group of gram negative, lactose fermenting, encapsulated, non-motile bacilli. they are important urinary tract pathogens, especially in long stay hospital patients and infection is often associated with urethral catheterisation. the laboratory characterisation of these organisms by biochemical means is time consuming and not entirely satisfactory. antibiotic sensitivity tests indicate that gentamicin is the drug of choice for treatment of a urinary tra ... | 1975 | 1094348 |
| cinoxacin: in vitro antibacterial studies of a new synthetic organic acid. | cinoxacin (compound 64716) is a synthetic organic acid with antibacterial activity against most aerobic gram-negative bacilli. minimal inhibitory concentrations of cinoxacin (agar-dilution method) were determined for 419 strains. escherichia coli was the most susceptible group of organisms. the majority of klebsiella sp., enterobacter sp., proteus sp., and serratia marcescens were inhibited by 8 mug of cinoxacin per ml. pseudomonas aeruginosa and all gram-positive isolates tested were resistant ... | 1975 | 1094949 |
| ampicillin, carbenicillin indanyl ester, and nifuratel in the treatment of urinary infection in domiciliary practice. | a total of 120 patients, including 53 pregnant women with significant bacteriuria, received 163 7-day courses of oral antimicrobial agents allocated in a randomised manner. the cure rates after 6 weeks' follow-up ranged from 73% to 86%, and there was no statistical difference between preparations of ampicillin, carbenicillin indanyl easter, and 2 different formulations of nifuratel. side-effects occurred in 30% to 40% of the courses of penicillin drugs, but in under 15% of the course of nifurate ... | 1975 | 1095107 |
| wound infections due to bacteroides fragilis following intestinal surgery. | ninety-six wound infections due to bacteroides fragilis occurring after intestinal surgery are described. most infections followed appendicectomy or colectomy for diverticulitis. b. fragilis was isolated in pure growth from 47 per cent of infections, and in mixed culture the other common bacteria were klebsiella spp., escherichia coli and enterobacter spp. fifty-three per cent of the infections responded rapidly to either non-specific measures or antibiotic therapy, but 47 per cent of patients d ... | 1975 | 1095111 |
| klebsiella pneumonia following an apparent staphylococcal pneumonia in a four-year-old child. | | 1975 | 1095280 |
| maintenance of fertility in the horse including artificial insemination. | a high fertility rate depends on many different factors and is always related to inheritance and enviorment. the successful feritly control system in the german thoroughbred breeding industry shows that fertility can be increased by good management and veterinary supervision. the insemination of horses with frozen semen is discussed. replacement of natural service by a.i. with frozen semen is not generally accepted in horsebreeding, as the conditions are entirely different from cattle breedi ... | 1975 | 1095367 |
| [aminoglycoside antibiotics from clinical viewpoint]. | indications, side effects, dosage and several pharmacokinetic properties of gentamicin, tobramycin, sisomicin, kanamycin, amikacin, and streptomycin are delt with in the first part. hereafter, some aspects are briefly mentioned concerning combinations of antibiotics with aminoglycosides, as well as indications for the evaluation and analysis of the aminoglycoside concentration in the serum. | 1975 | 1095500 |
| spontaneous bacterial peritonitis in cirrhosis: endemic or epidemic? | | 1975 | 1095846 |
| hospital-acquired infections-1. sources and types of infection. | | 1975 | 1096088 |
| [pneumopathies due to klebsiella pneumoniae]. | | 1975 | 1096251 |
| regional differences in patterns of urinary tract infections. | the identity of 693 pathogenic bacilli isolated from 2,175 urine specimens cultured during a two-year period in southeastern new mexico is presented along with results of sensitivity testing by kirby-bauer technique. the pattern of infections and sensitivity studies in hospitalized patients is compared with that of office patients and contrasted with results noted in other areas. | 1975 | 1096400 |
| urinary tract infections in black female children. | it has been demonstrated in several studies that prepubertal black females have a lower incidence of urinary tract infection than do white females of the same age. other racial differences in the natural history of urinary tract infection have been suggested, but thus far very few young black girls with urinary tract infection have been thoroughly studied. the records of 56 black female children with urinary tract infections were reviewed and the clinical, laboratory, and radiologic manifestatio ... | 1975 | 1096401 |
| effect of microorganisms isolated from the upper gut of malnourished children on intestinal sugar absorption in vivo. | the effect of microorganisms isolated from the upper gastrointestinal tract of malnourished children on intestinal sugar absorption was studied in rats in vivo. pure cultures of organisms were grown overnight in a nutrient broth and the resultant supernatant fluid which contained microorganisms in similar numbers to those found in the patients was used as the basic solution for jejunal perfusions which were done in anesthetized adult wistar rats. the substrate used was arbutin (p-hydroxphenyl-be ... | 1975 | 1096588 |
| long-term therapy for chronic bacteriuria in men. u.s. public health service cooperative study. | response to therapy, renal function, and mortality were analyzed in a prospective study of 249 men with bacteriuria followed for up to 10 years. all patients received initial organism-specific antibiotic therapy followed by 2 years of continuous treatment with sulfamethizole, nitrofurantoin, methenamine mandelate, or placebo. continuous therapy with active drugs delayed recurrence of bacteriuria and reduced acute clinical exacerbations of infection. patients with pure escherichia coli bacteriuri ... | 1975 | 1096704 |
| occurrence of klebisiella pneumoniae in surface waters. | the occurrence of klebsiella pneumoniae in surface waters was not found to be ubiquitous. when it was isolated, escherichia coli could also be found. the fecal coliform to fecal streptococci ratio suggest that its origin could be human, animal, or mixed sources. | 1975 | 1096815 |
| inhibition of microbial growth by fatty amine catalysts from polyurethane foam test tube plugs. | when polyurethane foam test tube plugs are autoclaved, they release volatile fatty amines that inhibit the growth of some microorganisms. the chemical structures of these amines were determined by the use of a gas chromatograph-mass spectrometer. they are catalysts used to produce the foam. the problem of contaminating growth media with toxic substances released from polymeric materials is discussed. | 1975 | 1096816 |
| malignant hypertension. recovery of kidney function after renal allograft failure. | a 28-year old patient with malignant hypertension developed endstage renal failure necessitating chronic maintenance hemodialysis for seven months and transplantation of a renal allograft that was rejected within a month. after this, with continued control of the hypertension, the patient's own kidneys gradually resumed function and achieved anendogenous creatinine clearance of 30 ml/min. she has not required further dialysis for more than nine months. recovery of sufficient renal function to ma ... | 1975 | 1096841 |
| adsorption of pneumocins and aerocins on bacterial cells. | adsorption of aerocins 1a-e26, 1b-e47, 1b-e43, 2-e26, 2-e47 and pneumocins a-114 and a-902 was found to be dependent on the presence of specific receptors on the surface of sensitive bacteria. resistant mutants, selected by these bacteriocins, were incapable of adsorption owing to loss or altered structure of receptors. maximal numbers of killing units of pneumocins and aerocins adsorbed by one bacterial cell of sensitive strains were determined. kinetics of adsorption and degree of killing of b ... | 1975 | 1096844 |
| [purification of beta-lactamases by affinity chromatography]. | affinity columns able to purifie beta-lactamases have been prepared either by linking covalently reversible inhibitors or substrates to agarose beds. the enzyme is eluted with a gradient of sodium chloride or released with the substrate. this method is a pertinent one for the purification of these enzymes and for the study of bacteria harbouring more than one beta-lactamase. | 1975 | 1096966 |
| proceedings: a bacteriological and clinical assessment of a new drug-oxolinic acid. | | 1975 | 1097025 |
| comparative in vitro acitvity of chloramphenicol and thiamphenicol on common aerobic and anaerobic gram-negative bacilli(salmonella and shigella excluded). | the antibacterial activity of thiamphenicol was compared to that of chloramphenicol against 313 strains of gram-negative bacilli isolated from various clinical specimens. these two antiboitics were equally active against the 106 isolates of haemophilus mic equals 0.1 minus 1.56 mu g/ml) and against 40 strains of bacteroides fragilis (almost all strains being inhibited by 12.5 mug/ml of the two drugs). in contrast, when compared with chloramphenicol, 2-16 times as much of thiamphenicol was requir ... | 1975 | 1097209 |
| evaluation of antibacterial activities of cephalosporin antibiotics: cefazolin, cephaloridine, cephalothin, and cephalexin. | the antibacterial activities of 4 cephalosporin antibiotics, cefazolin, cephaloridine, cephalothin and cephalexin, against 330 isolates of bacteria from patients at national taiwan university hospital, were determined by an agar plate dilution technique. cephalosporins possess strong antibacterial activity against gram-positive bacteria except enterococci. staphylococcus aureus is the most susceptible among the organisms tested. more than 90% of staphylococcus aureus strains are suppressed by ce ... | 1975 | 1097210 |
| bacterial studies of clindamycin-associated colitis. a preliminary report. | the cause of pseudomembraneous colitis is not known but has been attributed to an alteration in the microbial flora of the colon. to test this hypothesis, a blind, prospective study was undertaken in which fecal samples were cultured quantitatively for aerobic and anaerobic organisms. the patients from which these samples were taken were all receiving clindamycin and had diarrhea secondary to the use of the drug. we were able to show definite differences in the colonic microflora which correlate ... | 1975 | 1097297 |
| a field study of coliform mastitis in sows. | three sows with agalactia and mastitis were compared with 3 normally lactating sows at 8, 16, 24, and 32 hours postpartum. bacteriologic examination of milk resulted in isolation of klebsiella pneumoniae or escherichia coli from affected glands of all 3 agalactic sows. milk from clinically normal glands of affected sows and from glands of normal sows was culture-negative for coliforms. affected sows had higher rectal temperatures and lower milk yields, and pigs from affected sows had lower mean ... | 1975 | 1097381 |
| genes for ribitol and d-arabitol catabolism in escherichia coli: their loci in c strains and absence in k-12 and b strains. | escherichia coli c strains can grow at the expense of the two natural pentitols ribitol and d-arabitol, sugar alcohols previously thought not to be utilized by e. coli. e. coli strains k-12 and b cannot utilize either compound. the genetic loci responsible for pentitol catabolism in e. coli c, designated rtl and atl, are separate and closely linked. each lies between metg and his and is highly co-transducible with metg and with a p2 prophage attachment site. rtl and atl readily can be transduced ... | 1975 | 1097416 |
| radioimmunoassay, acetylating radio-enzymatic assay, and microbioassay of gentamicin: a comparative study. | gentamicin is an aminoglycoside antibiotic widely used to treat gram-negative bacillary infections. because it has a low therapeutic index, monitoring of serum levels may help to insure adequacy of dosage and avoid toxicity. microbiological assays are relatively slow and can be complicated by the presence of other antimicrobials. radioimmunoassay (ria) and acetylating radio-enzymatic assay (ara) are new methods for gentamicin assay which offer the following advantages: rapidity (less than 3 hour ... | 1975 | 1097551 |
| [significance of intraperitoneal administration of antibiotics in abdominal surgery (author's transl)]. | | 1975 | 1097760 |
| a method for isolating nonsense suppressors in enterobacteriaceae using an amber mutant of the drug resistance factor r1. | we describe here the isolation of a mutant derivative of the drug resistance factor r1 (meynell and datta, 1966) that carries a nonsense mutation in a gene determining resistance to penicillins. we have used this mutant r1 to isolate derivatives of escherichia coli and klebsiella pneumoniae that contain nonsense suppressors (sup- strains) by screening penicillin-resistant revertants of strains containing the mutant r factor for the presence of such suppressors. this obviates the need to have k ... | 1975 | 1097892 |
| role of toxigenic and invasive bacteria in acute diarrhea of childhood. | the cause of pediatric diarrhea in brazil was investigated with use of assays for toxigenic and invasive bacteria. potential etiologic agents were identified in 31 of 40 consecutive children with diarrhea: toxigenic escherichia coli or klebsiella in 20 patients (50 per cent); invasive esch, coli or salmonella in four (10 per cent), and both toxigenic and invasive organisms in seven (18 per cent). fecal leukocytes were present in nine of the 11 patients (82 per cent) with invasive pathogens. all ... | 1975 | 1097914 |
| klebsiella pneumoniae in endodontic therapy. report of a case. | a 48-year-old man underwent endodontic treatment of the lower left central incisor. in the course of treatment two acute exacerbations occurred. penicillin therapy was initiated at the time of the first exacerbation. it was ineffective, and a culture of the purulent exudate was taken at the time of the second acute response. the causative organism was klebsiella pneumoniae, which was found to be sensitive to tetracyclines. after tetracycline therapy, endodontic therapy was completed. healing has ... | 1975 | 1097986 |
| acute reversible renal failure in patients with acute cholecystitis and cholangitis. | although acute renal failure is a well recognized complication of several extra-hepatic biliary tract diseases especially biliary tract surgery in the presence of obstructive jaundice, there is little information concerning renal failure in acute cholecystitis. renal function was assessed in 14 patients with acute cholecystitis and two with acute cholangitis. six patients had no evidence of renal impairment, four had modest elevations of plasma urea and creatinine concentrations and six had acut ... | 1975 | 1098091 |
| [characteristics of capsular bacteria, isolated from children with acute intestinal diseases]. | a study was made of 256 young children suffering from gastroenterocolitis, dyspepsia, food poisoning for the presence of conditionally pathogenic representatives of the enterobacteriaceae family. klebsiellae were isolated in 39.8% of the patients and in 22.3% of 67 healthy children. a study was made of morphological, cultural-biochemical properties and the antigenic structure in 308 strains of the klebsiella denus. capsules were detected by microscopic examination. biochemical properties were de ... | 1975 | 1098332 |
| colonization of intensive care unit patients with gram-negative bacilli. | a prospective study of 64 patients admitted to a medical intensive care unit and 86 patients admitted to a surgical intensive care unit was done to determine the frequency of pharyngeal, intestinal, and tube site colonization with gram-negative bacilli. studies were carried out over a 13-week period. the pharyngeal carrier rate among the surgical patients increased by a total of 34 strains compared to 14 strains among medical patients. similarly, the intestinal carrier rate increased by 35 strai ... | 1975 | 1098452 |
| spectrum of cholangitis. | of 402 patients admitted with biliary disease over the last three years, cholangitis has been diagnosed in 36. this represents an 8.8 per cent overal incidence and a 33.8 per cent incidence among patients who have undergone operation or manipulation involving the common duct. based on this experience, a program of prophylaxis and treatment of cholangitis has been devised with special emphasis on the management of elderly patients in the initial postoperative period. | 1975 | 1098507 |
| bactericidal and opsonic activities of normal sheep serum against gram-negative bacteria. | the bactericidal and opsonic activities of normal sheep serum against 9 smooth and 4 rough strains of gram-negative bacteria were measured. three smooth strains-escherichia coli 3662, salmonella typhimurium, and salmonella gallinarum-were resistant to the bactericidal action of normal sheep serum with or without complement. six smooth strains-e coli o78:k80(b), salmonella arizonae, proteus inconstans, klebsiella pneumoniae, salmonella stanley, and salmonella abortus-equi-were moderately sensitiv ... | 1975 | 1098532 |