linezolid resistant staphylococcus haemolyticus: first case report from india. | linezolid is being increasingly used in the treatment of infections with gram-positive organisms especially methicillin resistant staphylococcal isolates. though resistance to this antimicrobial is emerging but it is extremely rare. here we document first case of linezolid resistant staphylococcus haemolyticus (s.haemolyticus) from india. this organism was isolated from pus oozing from a postsurgical site in 61 year old male hailing from an adjoining state of haryana. | 2012 | 23043928 |
antimicrobial metallic copper surfaces kill staphylococcus haemolyticus via membrane damage. | recently, copper (cu) in its metallic form has regained interest for its antimicrobial properties. use of metallic cu surfaces in worldwide hospital trials resulted in remarkable reductions in surface contaminations. yet, our understanding of why microbes are killed upon contact to the metal is still limited and different modes of action have been proposed. this knowledge, however, is crucial for sustained use of such surfaces in hospitals and other hygiene-sensitive areas. here, we report on th ... | 2012 | 22950011 |
autolytic activity and molecular characteristics of staphylococcus haemolyticus strains with induced vancomycin resistance. | the aim of this study was to investigate the molecular characteristics of induced vancomycin resistance in staphylococcus haemolyticus. autolytic properties and phenotypic characteristics of passage-selected vancomycin-resistant s. haemolyticus strains were examined. in addition, expression of autolysis-related genes (atl, lrgab, sara and lyts) was investigated using the rnase protection assay (rpa). the rpa results indicated that only the expression of the atl gene was significantly upregulated ... | 2012 | 22820692 |
multidrug-resistant coagulase-negative staphylococci in food animals. | to study the antimicrobial resistance of coagulase-negative staphylococci (cons) in animals. | 2012 | 22816491 |
staphylococcus haemolyticus strains target mitochondria and induce caspase-dependent apoptosis of macrophages. | the aim of this study was to investigate the interaction of staphylococcus haemolyticus strains with a macrophage cell line. infection with the strains resulted in macrophage injury. all strains exhibited cytotoxic effects towards j774 cells. moreover, the bacteria triggered apoptosis of the cells. the lowest apoptotic index did not exceed 21 %, whereas the highest reached 70 % at 24 h and 85 % at 48 h after infection. incubation with the bacteria caused loss of mitochondrial membrane potential ... | 2012 | 22660952 |
core genome conservation of staphylococcus haemolyticus limits sequence based population structure analysis. | the notoriously multi-resistant staphylococcus haemolyticus is an emerging pathogen causing serious infections in immunocompromised patients. defining the population structure is important to detect outbreaks and spread of antimicrobial resistant clones. currently, the standard typing technique is pulsed-field gel electrophoresis (pfge). in this study we describe novel molecular typing schemes for s. haemolyticus using multi locus sequence typing (mlst) and multi locus variable number of tandem ... | 2012 | 22484086 |
clonal dissemination of linezolid-resistant staphylococcus haemolyticus exhibiting the g2576t mutation in the 23s rrna gene in a tertiary care hospital in brazil. | | 2012 | 22314531 |
the use of daptomycin and linezolid to treat vancomycin-intermediate staphylococcus haemolyticus infection in a premature infant. | infections with staphylococcal species, especially coagulase-negative staphylococci are common after neurosurgical procedures. we report a case of a coagulase-negative staphylococci infection of a ventricular shunt site in a 105-day-old, premature infant born at 25 weeks gestation with multiple medical problems. the patient was successfully treated with a combination of daptomycin and linezolid for the persistent infection, which was increasingly resistant to vancomycin. the patient was initiall ... | 2010 | 22477818 |
[antimicrobial sensitivity of the environmental microbiota in the intensive care units of a peruvian hospital]. | the objective was to detect gram-negative bacilli and gram-positive cocci isolated from the environmental microbiota of the intensive care unit (icu) departments of neonatology, pediatrics, and transplants (kidney, liver, and general) in a lima hospital and determine their antimicrobial sensitivity. eighty samples were obtained from inanimate surfaces using a wet swab. a total of 61 bacterial strains were identified, including staphylococcus epidermis (46.0%), alcaligenes sp. (21.3%), pseudomona ... | 2017 | 28538851 |
staged reimplantation of a total hip prosthesis after co-infection with candida tropicalis and staphylococcus haemolyticus: a case report. | fungal prosthetic joint infection is a rare complication in total joint arthroplasty. there are no established guidelines for management of these infections. we present a case of a 53-year-old male with a hip joint prosthesis co-infected with candida tropicalis and staphylococcus haemolyticus. a two-stage exchange arthroplasty was performed. the patient underwent implant removal, debridement, irrigation with saline solution and application of cement spacer impregnated with vancomycin followed by ... | 2017 | 28735470 |
collaborative research on puerperal infections in bangladesh. | bangladesh is considered as a high-risk country for emerging infectious diseases because of its high population density, poverty, and unhygienic conditions. although control efforts have primarily been focused on major infectious diseases such as diarrheal diseases, tuberculosis, malaria, and hiv infection, the prevalence and impact of many local or minor infectious diseases are still unclarified in this country. in this review, we present our recent experience and outcomes of collaborative rese ... | 2017 | 28552890 |
[effects of application of vancomycin in the early stage of patients with extremely severe burn]. | objective: to evaluate the effects of application of vancomycin in the early stage of patients with extremely severe burn, in order to provide reference to drug for anti-infection treatment in the early stage of patients with extremely severe burn. methods: data of 15 patients of kunshan explosion on august 2nd, 2014, admitted to the department of intensive care in our hospital were retrospectively analyzed. the clinical efficacy of continuously intravenous dripping of vancomycin (combined with ... | 2017 | 28427133 |
distribution of non-aureus staphylococci species in udder quarters with low and high somatic cell count, and clinical mastitis. | the effect of non-aureus staphylococci (nas) in bovine mammary health is controversial. overall, nas intramammary infections (imi) increase somatic cell count (scc), with an effect categorized as mild, mostly causing subclinical or mild to moderate clinical mastitis. however, based on recent studies, specific nas may affect the udder more severely. some of these apparent discrepancies could be attributed to the large number of species that compose the nas group. the objectives of this study were ... | 2017 | 28456402 |
prevalence of non-aureus staphylococci species causing intramammary infections in canadian dairy herds. | non-aureus staphylococci (nas), the microorganisms most frequently isolated from bovine milk worldwide, are a heterogeneous group of numerous species. to establish their importance as a group, the distribution of individual species needs to be determined. in the present study, nas intramammary infection (imi) was defined as a milk sample containing ≥1,000 cfu/ml in pure or mixed culture that was obtained from a cohort of cows assembled by the canadian bovine mastitis research network. overall, 6 ... | 2017 | 28527793 |
high prevalence of methicillin-resistant coagulase-negative staphylococci isolated from a university environment in thailand. | the present study was conducted to isolate and characterize the molecular epidemiology of the methicillin-resistant staphylococci in the general university environment, where all five locations; the library, restrooms, canteens, computer rooms and outdoor surfaces, are in common use by a large population of students. we used mannitol salt agar (msa) supplemented with 4 μg/ml of oxacillin to screen the methicillin-resistant staphylococci. the species level was identified by pcr of rdr (staphyloco ... | 2017 | 28617524 |
phenol-soluble modulin toxins of staphylococcus haemolyticus. | coagulase-negative staphylococci (cons) are important nosocomial pathogens and the leading cause of sepsis. the second most frequently implicated species, after staphylococcus epidermidis, is staphylococcus haemolyticus. however, we have a significant lack of knowledge about what causes virulence of s. haemolyticus, as virulence factors of this pathogen have remained virtually unexplored. in contrast to the aggressive pathogen staphylococcus aureus, toxin production has traditionally not been as ... | 2017 | 28596942 |
phenotypic characterisation of coagulase-negative staphylococci isolated from blood cultures in newborn infants, with a special focus on staphylococcus capitis. | this swedish study determined which species of coagulase-negative staphylococci (cons) were found in neonatal blood cultures and whether they included staphylococcus capitis clones with decreased susceptibility to vancomycin. | 2017 | 28631328 |
quarter- and cow-level risk factors for intramammary infection with coagulase-negative staphylococci species in swiss dairy cows. | bacteriological status, evaluation of udder symmetry, udder hygiene, and teat end scores of 92 dairy cows were assessed on 3 swiss dairy farms in a longitudinal 1-yr study to determine risk factors for intramammary infection (imi) with coagulase-negative staphylococci (cns) species. farm visits were performed monthly including sterile quarter milk sampling and udder evaluation of all lactating cows. milk samples were evaluated for the presence of staphylococci using selective agar plates. specie ... | 2017 | 28477997 |
biofilm formation of methicillin-resistant coagulase negative staphylococci (mr-cons) isolated from community and hospital environments. | methicillin-resistant coagulase negative staphylococci (mr-cons) are the major cause of infectious diseases because of their potential ability to form biofilm and colonize the community or hospital environments. this study was designed to investigate the biofilm producing ability, and the presence of meca, icaad, bap and fnba genes in mr-cons isolates. the mr-cons used in this study were isolated from various samples of community environment and five wards of hospital environments, using mannito ... | 2017 | 28859149 |
changing epidemiology of coagulase-negative staphylococci in normal flora of skin. | coagulase negative staphylococci (cons) have recently emerged as important pathogens causing nosocomial blood stream infections. to evaluate the prevalence of cons in cutaneous normal flora, skin swabs were collected from voluntary blood donors and processed for culture and identification using matrix assisted laser desorption ionisation-time of flight (maldi-tof). cons were isolated from 96% of blood donors, most commonly staphylococcus hominis (86%), followed by staphylococcus epidermidis (22% ... | 2017 | 28681820 |
coagulase-negative staphylococci in human milk from mothers of preterm compared with term neonates. | human milk is the preferred nutrition for neonates and a source of bacteria. research aim: the authors aimed to characterize the molecular epidemiology and genetic content of staphylococci in the human milk of mothers of preterm and term neonates. | 2017 | 28418807 |
high-quality genome sequence of the highly resistant bacterium staphylococcus haemolyticus, isolated from a neonatal bloodstream infection. | using illumina hiseq and pacbio technologies, we sequenced the genome of the multidrug-resistant bacterium staphylococcus haemolyticus, originating from a bloodstream infection in a neonate. the sequence data can be used as an accurate reference sequence. | 2017 | 28729278 |
prevalence of methicillin resistance and macrolide-lincosamide-streptogramin b resistance in staphylococcus haemolyticus among clinical strains at a tertiary-care hospital in thailand. | staphylococcus spp. is a major cause of nosocomial infection and sepsis. however, increasing drug resistance is becoming a challenge to microbiologists. the purpose of this study was to identify and determine antimicrobial resistance phenotypes and drug resistance genes of clinical coagulase-negative staphylococci (cons) isolates at mae sot hospital in tak province, thailand. a total of 229 cons isolates were collected from clinical specimens during two periods in 2014 and in 2015. staphylococcu ... | 2017 | 28702199 |