| the extensive cross-reaction of several syngeneic rat-anti-bp antiserums with myelin basic proteins (bp) of other species. | | 1976 | 59689 |
| molecular requirements involved in suppression of eae by synthetic basic copolymers of amino acids. | | 1976 | 59690 |
| immunological relationships among hexosaminidases of different species. | | 1976 | 59695 |
| rosette formation between human lymphocytes and sheep erythrocytes. inhibition of rosette formation by specific glycopeptides. | rosette formation with unsensitized sheep erythrocytes is a characteristic of human thymus dependent lymphocytes. release of glycopeptides from the sheep erythrocyte by trypsin reduces rosette formation. these tryptic glycopeptides inhibit rosette formation by untrypsinized sheep erythrocytes; this suggests that rosetting is mediated by erythrocyte surface glycopeptides. to investigate the molecular nature of this interaction, we examined the abilities of various model compounds to act as hapten ... | 1976 | 59739 |
| anaphylactoid reaction to single-component pork insulin. | | 1976 | 59824 |
| [diamine oxidase and clinical significance of the enzyme]. | | 1976 | 59922 |
| experimental studies on drug sensitization. ii. production of antiacetylsalicylyl antibodies and their detection by passive hemagglutination. | antiacetylsalicylyl antibodies were produced in rabbits and guinea-pigs by innoculation of acetylsalicylic acid incorporated in freund adjuvant. these antibodies were readily detected by a passive hemagglutination test using rabbit erythrocytes incubated with acetylsalicylic acid at alkaline ph. acetylsalicylyl conjugates with human gammaglobulin, bovine gammaglobulin and rabbit gammaglobulin were also prepared by incubating the proteins with acetylsalicylic acid at alkaline ph. in parallel expe ... | 1976 | 59932 |
| guinea-pig ia antigens: functional significance and chemical characterization. | | 1976 | 59972 |
| [differences of antigenicity and histaminereceptors between myocardium and smooth muscles]. | | 1975 | 60010 |
| chlorpromazine-induced histamine release from guinea-pig skin in vitro--a photosensitive reaction. | chlorpromazine releases histamine from chopped guinea-pig skin maintained in vitro at 37 degrees c. this effect was markedly potentiated by radiant energy. this potentiation increased with increasing exposure to radiant energy. the possible clinical applications of these findings are discussed. | 1976 | 60086 |
| the action of local anaesthetics on histamine release. | | 1976 | 60105 |
| responses of cancer patients in the mem test: not just a function of charge on basic proteins. | it has been reported that lymphocytes from cancer patients give positive responses to ppd, myelin basic protein, tumour basic protein, and certain histone fractions in the mem test. the underlying mechanisms of the mem test are poorly understood, but it is widely assumed that it detects immunological sensitization to specific antigenic determinants. the cross-reactivity experienced is interpreted as indicating shared antigenicity. since all the stimulatory proteins are strongly basic we investig ... | 1976 | 60119 |
| biological approaches to the study of the keratinization process. | | 1976 | 60201 |
| hemagglutination of neuraminidase-treated human erythrocytes by leishmania enriettii infected guinea-pig sera. | sera from guinea-pigs infected with the protozoan parasite leishmania enriettii showed higher hemagglutination (ha) titres for neuraminidase treated human erythrocytes than those of normal guinea-pig sera. this ha activity was associated mostly with the 19s fraction of the immune serum and could be absorbed out with an antigenic fraction of the parasite membrane. antigenic determinants involved in this ha reaction consisted of, at least, beta-d-galactosyl or lactosyl residues. | 1976 | 60254 |
| studies on chemically modified forms of the myelin basic protein: requirements for encephalitogenicity. | | 1976 | 60258 |
| cellular localization of intestinal calcium-binding protein in pig duodenum. | the gamma-globulin fraction of a rabbit antiserum against porcine intestinal calcium-binding protein (cabp) was used in an immunoperoxidase method to study cabp localization in porcine duodenal tissue. specific immunostaining, indicative of the presence of cabp, was noted within the cytoplasm of the duodenal epithelial cells. no cabp was detected in goblet cells or in the subepithelial layers. when the specific antibody was replaced by either nonimmune rabbit gamma-globulin or when the specific ... | 1976 | 60264 |
| conclusions about aminopeptidase in tissue sections from studies of amino acid naphthylamide hydrolysis. | catalytic properties (km, vmax) of aminopeptidase in pig kidney sections, in isolated membranes and in a solubilized purified form were investigated using amino acid 2-naphthylamides and 4-methoxy-2-naphthylamides. in the first case these properties were estimated on the basis of the stain intensity resulting from the coupling of product with fast blue b, in the latter two cases they were measured fluorometrically. the following observations were made: (1) in all three cases the substrate turnov ... | 1976 | 60318 |
| [on the endogenous peroxidase in the spleen of swine (author's transl)]. | we studied the distribution of endogenous peroxidase in the spleen of swine by modifications of the graham and karnovsky diaminobenzidine procedure. there is a peroxidatic activity in the majority of the ellipsoid cells (cells of the sheathed capillaries of schweigger-seidel), which is localized in the endoplasmic reticulum and the perinuclear cisterna. this staining is inhibited completely by aminotriazole and is rapidly destroyed even by low concentratoins of glutaraldehyde. furthermore, the r ... | 1976 | 60325 |
| central and peripheral localization of somatostatin. immunoenzyme immunocytochemical studies. | | 1976 | 60436 |
| an evaluation of a procedure for the isolation of myelin basic protein (bp). | a detailed description and stepwise evaluation of a procedure that can be used to obtain myelin basic protein (bp) from whole brain is presented. the procedure involved the 0.001 mhc1 extraction of whole brain pre-treated in a sequential manner with chloroform-methanol (2:1 v/v), acetone, and deionized water. this is followed by a precipitation of the extract at ph 9.0, and gel filtration of the supernatant in 0.01 m hc1. yields of canine and porcine bp and their disc gel evaluations are present ... | 1976 | 60758 |
| detection of beta2-microglobulin in sera from diverse vertebrate species by the use of a heterologous radioimmunoassay. | the strong cross-reaction between rabbit and human beta2-microglobulins, as detected by goat antisera, has permitted the development of heterologous radioimmunoassays to detect homologues of beta2-microglobulin (beta2mu) in the sera of various vertebrate species. the assay based on the inhibition of the binding reaction between goat anti-rabbit beta2 mu and human beta2 mu divided the sera examined into two groups, one giving high levels of inhibition (approximately 80%). and the other lower leve ... | 1976 | 60779 |
| [electric reaction of the cochlea to the administration of ototoxic antibiotics into the scala tympani and the endolymphatic duct (experimental study)]. | | 1976 | 60820 |
| [proceedings: effect of histamine-h2-receptor-blockaders on biosynthesis and catabolism of histamin e in gastric mucosa]. | | 1976 | 60836 |
| serological evidence and isolation of a virus closely related to the human a/hong kong/68 (h3n2) strain in swine populations in czechoslovakia in 1969-1972. | | 1976 | 60851 |
| glucuronide conjugation in the lung. | | 1976 | 60876 |
| release of active substances during anaphylaxis. | | 1976 | 60877 |
| the biological origin of antibody diversity. | antibody diversity has a compelling fascination for many scientists and over the years speculations have sometimes seemed more numerous than facts. now the structural basis of antibody specificity is well defined. amino acid sequences and recently three-dimensional structures of various immunoglobulins provide the most solid basis for discussing the origin of diversity. the novel pattern of variable (v) and constant (c) regions of amino acid sequence has been resolved further to show the functio ... | 1976 | 60909 |
| [plasma concentration curves of catecholamines and corticosteroids as well as pbi in swine kept under various conditions and acutely exposed to cold]. | the response to acute cold (-5 degrees c) of swine kept single was found to differ from that of animals kept in groups. such difference in reaction was reflected in significant variation of plasma concentration curves in catechol amines and 11-ohks during and after acute exposure to cold. the response to cold stimulation of animals kept single was primarily and pronouncedly via the sympathicoadrenal system, whereas animals kept in groups responded to acute cold exposure, with the hypothalamic-ad ... | 1976 | 60980 |
| the a(w) subdeterminants. | | 1976 | 61018 |
| [antigen specific to spermatozoal cell membrane and male sterility--isolation of specific antigen]. | | 1976 | 61084 |
| tolerance to contact hypersensitivity. | | 1976 | 61098 |
| structure and function of beta2-microglobulin. | | 1976 | 61099 |
| the function of macrophages in t-lymphocyte antigen recognition. | | 1976 | 61101 |
| immunology of the acetylcholine receptor. | myasthenia gravis is a spontaneously occurring autoimmune disease in which antibodies and lymphocytes are specifically reactive with nicotinic ach receptors of skeletal muscle. antibodies reactive with junctional receptors of human muscle are found in 90% of patients with myasthenia gravis and not at all in other diseases. their capacity to cross the placenta suggests their involvement in the pathogenesis of neonatal myasthenia. the role of the thymus in myasthenia gravis remains a mystery, but ... | 1976 | 61167 |
| immunological aspects of sperm receptors on the zona pellucida of mammalian eggs. | sperm receptor sites on the surface of the zona pellucida are believed to be necessary for fertilization on the mammalian egg. ovary specific antibodies are known to precipitate the zona pellucida and are also responsible for inhibition of sperm binding and subsequent fertilization. the nature of the proposed receptor sites which are blocked by antibodies are discussed relative to comparable studies in which phytoagglutinins and other agents are used to determine the chemical nature of sperm rec ... | 1976 | 61169 |
| reverse plaque formation by hog cholera virus of the gpe-strain inducing heterologous interference. | a simple and rapid plaque procedure was developed for the assay of hog cholera virus (hcv) of a particular strain, gpe-, based on its intrinsic interference with vesicular stomatitis virus (vsv) on the primary swine testicle cells and on an established swine kidney cell line; the procedure is called the reverse plaque formation (rpf) method. the plaques were produced as colonies of hcv-infected cells which were vsv-sensitive, disintegrated cell sheet. these plaques became visible after 15 to 20 ... | 1976 | 61176 |
| cellular patterns of post-mortem glycogenolysis in longissimus dorsi muscles of pigs at different live weights. | serial frozen sections of longissimus dorsi muscles from twelve canadian yorkshire breed pigs at different live weights (13-86 kg) were stained for glycogen by the periodic acid-schiff (pas) reaction and reacted for nad tetrazolium reductase to determine the mitochondrial content of muscle fibres. sections from muscles taken immediately post mortem and at 5 hr post mortem were compared and the patterns of glycogenolysis in high, intermediate and low mitochondrial content fibres were assessed on ... | 1976 | 61191 |
| the major histocompatibility complex of the guinea-pig. ii. relationship between mixed leucocyte reactivity and serologically-defined phenotypes of the gpla b locus and i region. | the relationship between the mixed leucocyte reaction (mlr) and the serologically-defined antigens controlled by genes in the guinea-pig b locus (equivalent to the murine d or k region) and i region was investigated in various inbred and partially inbred strains and in guinea-pig families homozygous for their gpla alleles. no mlr reactions could be detected among guinea-pig families of a closed colony which had been bred to homozygosity for their gpla antigens. by contrast, animals which differe ... | 1976 | 61245 |
| regression of athrosclerosis. | | 1976 | 61350 |
| transmissible agents from human sarcoid and crohn's disease tissues. | mice were inoculated with human sarcoid tissue homogenates or with a first or a second passage homogenate of mouse tissue (including 0.2 mum membrane filtrates) originating from the inoculation of human sarcoid, crohn's disease, or control tissue homogenates. epithelioid and giant cell granulomas were present in the footpads and/or viscera of some of the mice given homogenates originating from each sarcoid or crohn's disease tissue 15 months after inoculation but were not present in mice given c ... | 1976 | 61441 |
| effects of antacids on gastrointestinal absorption of drugs. | antacids interfere with gastrointestinal drug absorption by either increasing or decreasing the rate at which a drug is absorbed, or the total quantity absorbed. antacids influence drug absorption by alteration of ionization state or solubility, factors dependent upon ph. antacids also delay gastric emptying and are capable of chelation and adsorption with susceptible products. many of these factors participate to produce the effect on gastrointestinal drug absorption in individual patients. | 1976 | 61596 |
| effects of midodrine, st 1059, methoxamine and glycine on spontaneously beating guinea-pig atria. | the chronotropic effects of midodrine, glycine (10(-8) to 3.10(-3) m), st1059 and methoxamine (10(-8) to 10(-3) m) were investigated in the spontaneously beating guinea-pig right atrial preparation. midodrine and glycine produced a slight, but significant rise in atrial rate over a wide concentration range. the midodrine-induced rise in atrial rate was not influenced by the beta-adrenergic receptor blocking drug propranolol (10(-6) m). the histamine (h2)-receptor blocking drug metiamide (3.10(-5 ... | 1976 | 61715 |
| comparative serological studies with mammalian adenoviruses. | nine serotypes of bovine adenovirus, five serotypes of ovine adenovirus, and four serotypes of porcine adenovirus were compared in reciprocal cross-neutralisation tests, to determine if viruses isolated from different species were indeed distinct serotypes. in addition, the above serotypes were tested for possible antigenic relationships with 28 of 32 human adenoviruses, by one-way cross neutralisation tests with human adenovirus antisera. the results indicated that all viruses tested were disti ... | 1976 | 61747 |
| evaluation of macrophage electrophoretic mobility (mem) test as an indicator of cellular immunity in ocular tumours. | the macrophage electrophoretic mobility (mem) test of field and caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was some indication of discrimination between choroidal melanoma and ocular inflammation. in our hands the test failed to give a reproducible result for the immunodiagnosis of ocular malignancy. the technique, however, seems to provide some indication of delayed hypersensitivity in experimental inflammatory e ... | 1976 | 61762 |
| retrograde axoplasmic transport to inactive dopamine beta-hydroxylase in sciatic nerves. | the transport of dopamine-beta-hydroxylase (dbh) in sciatic nerves was studied both by measuring the accumulated enzyme activity and by examining the accumulated immunologically reactive dbh protein. the pattern of dbh accumulation in the proximal segment was similar either in the activity or in the immunofluorescence. in the distal segment, however, much higher accumulation of immunofluorescence than that of the activity was observed 7 h after ligation. the immunotitration studies indicated tha ... | 1976 | 61789 |
| sleep patterns of the laboratory cat. | the effects of feeding schedule and external stimuli on sleep patterns were investigated in cats fed to maintain their mean body weight. the ecog, eog and emg wer recorded from 3 male cats fed once daily and under a 12:12 light--dark schedule. the results for 15 working days were compared with those obtained at week-ends and under continuous lighting, fasting, reduced food intake or overfeeding. feeding was also divided into 3 meals per day. despite some differences in their responsiveness. all ... | 1976 | 61852 |
| detailed analysis of a reciprocal translocation (13q-; 14q+) in the domestic pig by g- and q-staining techniques. | | 1976 | 61957 |
| the concept of regioselectivity in drug metabolism. | | 1976 | 62048 |
| activation of complement by the alternative pathway as a factor in the pathogenesis of periodontal disease. | dental plaque and a bacterium, actinomyces viscosus, isolated from plaque that can reproduce periodontal disease in germ-free rats, are activators of complement by the alternative pathway. it is suggested that this process is involved in the pathogenesis of chronic inflammatory periodontal disease. | 1976 | 62218 |
| p.g.x: a natural antithrombotic substance. | | 1976 | 62219 |
| haemagglutinin from rotavirus. | | 1976 | 62238 |
| [peripheral leukocyte migration inhibition test as an indication of specific reactivity of lymphocytes in delayed hypersensitivity]. | | 1976 | 62352 |
| the effect of lindane and phenobarbital on microsomal enzyme induction in dogs and miniature swine. | | 1976 | 62420 |
| sepcific tubercle antigen. | identification and isolation of the specific antigen of m. tuberculosis with the aid of an antiserum against the antigen antibody complex prepared by goudie's method from the serum of tberculous patients is described. the position of the specific antigen on the disc electrophoresis column comprising four protein bands has been identified and separated. the antibody has been identified as igg. more sophisticated techniques should enable the isolation of the specific antigen in practical amounts. ... | 1976 | 62437 |
| inactivation of lysis of oncornaviruses by human serum. | | 1976 | 62448 |
| species-common antigen of connective tissues. | collagen-free extracts were prepared from bovine, porcine and canine hyaline, elastic and fibrous cartilages, articular capsule, tendon, aorta, cortical bone and regenerating articular surfaces. the extracts were investigated with antisera to bovine nasal septal cartilage, dog articular cartilage and non-collagenous protein fraction of bovine cortical bone. immunodiffusion, immunoelectrophoresis, and immunohistochemical methods were used. in the different supporting tissues of the three animal s ... | 1975 | 62479 |
| [mast cells as regulators of tissue homeostasis and their place in the series of biological regulators]. | the most essential features of the mast cell are continuous production (and partially also absorption from the environment), deposition, and secretion of the two groups of biologically active substances of the regulatory type: heparin and other acid clycosaminoglycanes, and also histamine and, probably, other biogenic amines. these substances are antagonists and have an influence on the homeostasis of the microregion (capillary-connective tissue-parenchyma) -- the main area of action of the mast ... | 1976 | 62566 |
| structural and topological homology between porcine intestinal and renal brush border aminopeptidase. | a method for the preparation of closed, right-side-out vesicles from the brush border membrane of the kidney proximal tubules is described. the aminopeptidase known to be bound to this membrane was investigated in order to compare its properties with those already reported for the intestinal enzyme. both are composed of a hydrophilic, catalytically active part lying on the external side of the membrane and a short hydrophobic domain probably located in the n-terminal region of one of the subunit ... | 1976 | 62588 |
| endogenous type-c rna viruses of mammalian cells. | | 1976 | 62589 |
| the kurloff cell. its differentiation in the blood and lymphatic system. | kurloff cells belong to the group of macrophages as far as ultrastructure, adhesiveness and identification with kupffer cells (in the case of the liver) are concerned. a characteristic group of features makes it easy to recognize them: pas reaction, cyanol-blue staining, presence of myelin figures in electron microscopy and attachment to glass-slides. kurloff cells are thymic and blood cells. they are observed in small numbers in the circulating blood and, in large quantities, in spleen (red pul ... | 1976 | 62619 |
| activation of chymotrypsinogen by boar acrosin and its prevention by antiboar acrosin rabbit gamma-globulins. | activation of chymotrypsinogen by bovine trypsin or boar sperm acrosin was followed up using nalpha-acetyl-l-tyrosine ethyl ester in a highly sensitive test system. inhibition studies employing antiboar acrosin rabbit gamma-globulins showed the following results. 1) whereas the acrosin-induced activation velocity was significantly depressed in the presence of the antibodies, the trypsin-catalyzed activation rate was not diminished. 2) the antibodies enhanced the acrosin-catalyzed cleavage rate o ... | 1976 | 62699 |
| influence of boar acrosin antibodies produced in rabbit and sheep on chymotrypsinogen activation catalyzed by acrosin from boar, bull, ram, rabbkt and human. | activation of bovine chymotrypsinogen is catalyzed with increasing velocity by human, rabbit, boar, bull and ram acrosin. antiboar-acrosin rabbit gamma-globulins cause a significant reduction in the proenzyme activation rate induced by boar and bull acrosin, but only a weak reduction or none if ram or rabbit acrosin is the activating agent. the antiboar-acrosin gamma-globulins from sheep strongly inhibit chymotrypsinogen activation by ram, bull and boar acrosin, and significantly inhibit the hum ... | 1976 | 62700 |
| [studies on tissue level of anticancer drugs with special reference to the distribution into oral region part i: bleomycin (author's transl)]. | | 1976 | 62816 |
| substance p: a naturally occurring transmitter in human spinal cord. | immunoreactive substance p-like material has been found in axonal processes of human spinal cord in a location similar to that in other mammals. substance p may be a primary sensory transmitter (or modulator) in man. | 1976 | 62902 |
| substance p. | | 1976 | 62908 |
| lymphomas and animal-protein consumption. | geographic comparison reveals a positive correlation between consumption of animal protein, particularly bovine protein, and lymphoma mortality. allied observations suggest that excessive consumption of animal protein may, through antigen absorption and chronic persistent stimulation, impose considerable wear and tear on lymphoid tissue and thereby encourage malignant changes. | 1976 | 63007 |
| the cellular origin of motilin in the gastrointestinal tract. | the semithin-thin technique applied to serial resin-embedded sections, using sequential immunocytochemistry, conventional electron microscopy and silver staining, indicates that a population of enterochromaffin cells in the intestine contain, and therefore presumably synthesize and secrete, the 22-amino acid residue peptide motilin. | 1976 | 63139 |
| immunological aspects of hepatocellular carcinoma in the guinea-pig. | experimental observations were made on hepatic cancer induced with diethylnitrosamine (den) in guinea-pigs. two cancer cell lines have been established in tissue culture and their antigenicity investigated. tumour antignes were not found on normal liver cells, liver cells damaged wtih carbon tetrachloride and fetal liver cells obtained from fetuses more than 35 days old. the possibility of using immunological techniques to investigate the antigenicity of human cancer is discussed. | 1976 | 63151 |
| [use of experimental animals in the prediction of undesirable effects of nonsteroidal anti-inflammatory agents]. | | 1976 | 63155 |
| a bodian method for mounted frozen sections. | for application of the bodian method to frozen sections, cut frozen peripheral nerve or muscle at 10 mum and mount. fix for 4 days in 18 parts 80% ethanol, 1 part 10% formalin, and 1 part glacial acetic acid. fix central nervous tissue in the same mixture prior to freezing and sectioning, and after mounting postfix for 4 days. impregnate by the bodian procedure. the results equal bodian stains of paraffin sections. the technique is simple and reliable. the use of 10 mum frozen sections produces ... | 1976 | 63161 |
| hla factors and immune function. | the hla system is the major histocompatibility system (mhs) in man and contains a variety of closely linked genes, which control a large number of alloantigens, some complement components, and certain immune responses. the alloantigens are of three different kinds: (i) so-called "classical" or serologically detectable (sd) antigens which are present on all nucleated cells and controlled by genes of at least three different loci; (ii) mlc (= mixed lymphocyte culture = ld = lymphocyte dependent) a ... | 1976 | 63212 |
| studies on actions of prostaglandins in the lung. | | 1976 | 63228 |
| [effect of long-lasting noise on the plasma concentration of catecholamines, glucocorticosteroids and pbi in pigs]. | exposure of pigs with a body mass of 25-30 kg to long-lasting motor noise (108 db, 60-8000 hz, 72 hours) results in a considerable increase of catecholamine concentration in the plasma. coincidently there is a sharp continuous decrease of the 11-ohks in the plasma during the whole period of exposure to noise. immediately after stopping the acoustic irritation the concentration of plasma corticosteroids increases again. the electroencephalogram (eeg) giving evidence of inhibition signs during exp ... | 1976 | 63272 |
| latent homology of murine lymphoid antigens revealed through the complement mediated absorption of xenogeneic antiserum. | xenoantiserum against c57bl/6 mouse spleen cells was produced by immunization of rabbits. such antiserum displayed cytotoxic activity for several strains of mice. standard "in vitro" absorption removed species specific antibody revealing antibody directed against the c57bl/6 strain. when the xenoantiserum was absorbed with dba/2 spleen cells in the presence of complement, the binding of anti-c57bl/6 was increased. such data suggest that xenoantibodies directed against spleen cells possess a broa ... | 1976 | 63296 |
| persistence of transferable drug resistance in the lactose-fermenting enteric flora of swine following antimicrobial feeding. | six groups of swine (85 animals) were fed a combination of antimicrobial drugs (sulfamethazine 100 g/ton, chlortetracycline 100 g/ton and penicillin 50 g/ton). after two weeks the antimicronial drugs were removed from the diet of two groups (28 animals). these swine were compared to four groups fed the medicated diet to determine the effect of duration of treatment and degree of animal isolation on the persistence of resistance in lactose-fermenting enteric organisms. the degree of resistance to ... | 1976 | 63311 |
| [suppression of humoral antibody formation in rabbits. administration of alpha globulin fraction of human plasma and antilymphocytic globulin (author's transl)]. | | 1976 | 63333 |
| the effects of bcg on both cellular and humoral immunity during the early response to a hapten carrier complex. | cell-mediated reactions to the carrier and antibody-mediated reactions to hapten and carrier were studied in guinea-pigs treated with a single i.v. injection of bcg at different intervals of time before immunization with two different doses of a hapten-carrier complex. the results clearly show that bcg-induced delayed hypersensitivity reactions to the carrier and decreased antibody synthesis to the hapten. it is proposed that bcg acts on a dispatcher cell which controls both cellular and humoral ... | 1976 | 63343 |
| purification and characterization of human liver specific f antigen. | this paper reports the properties of purified human f antigen (liver-specific antigen). homogenates of liver in 0-25 m sucrose were centrifuged at 105,000 g. the supernatants were chromatographed on sepharose 6-b and four major peaks were separated. the third peak proved to be predominantly f antigen. this fraction was subsequently subjected to deae-cellulose column chromatography and f antigen was eluted at a concentration less than 0-2 m nacl in 0-01 m sodium phosphate buffer (ph 7-2). finally ... | 1976 | 63344 |
| a comparison of the inhibition of phosphodiesterase activity and allergic histamine release by disodium cromoglycate and compound i.c.i. 74917. | | 1976 | 63402 |
| the inhibition of histamine release from guinea-pig lung by compound i.c.i. 74917 and isoprenaline. | | 1976 | 63403 |
| [synthetic compounds with fibrinolytic and thrombolytic activity. i. pharmacologic observations]. | | 1976 | 63421 |
| [liberation of plasminogen activators]. | | 1976 | 63428 |
| in vitro inhibition of lactate dehydrogenases by kepone. | | 1976 | 63476 |
| host response to tumor-associated fetal antigens: kinetics and components. | using a colony-inhibition bioassay that measures the contribution of the host response in transplantation immunity to tumor-associated fetal antigens (tafa), i evaluated the occurrence of tafa during different developmental stages of murine fetal liver cells. a maximum concentration of tafa was present at approximately 15 days' gestation. a similar age-equivalence phase of gestation was also found in pig fetal liver. host-response kinetics to tafa were examined, and results indicated a similar p ... | 1976 | 63559 |
| [radioimmunological analysis of growth hormone with the aid of soviet diagnostic agent]. | | 1976 | 63610 |
| behaviour in ferrets of swine influenza virus isolated from man. | after intranasal instillation into ferrets, the "swine" influenza virus a/new jersey/8/76(hsw1 n1) had a 50% minimal infectious dose similar to that of previously tested a/pr/8-a/england (h3 n2) recombinants virulent and attenuated for man. a/new jersey produced only a mild upper respiratory tract infection. however, higher titres of virus were recovered from the lungs over a longer period than experienced previously with asian and hong kong virus strains. there was a diphasic pyrexia the second ... | 1977 | 63712 |
| immunochemical evidence of cholecystokinin-like peptides in brain. | | 1976 | 63918 |
| [transmission of enteroviruses and their antigenic variation due to antibody (author's transl)]. | | 1975 | 64015 |
| sterilized hepatitis b (surface) antigen for production of specific antisera. | the combined treatment with beta-propiolactone and ultraviolet rays described for the sterilization of hbsag-positive sera does not interfere with the purification procedures for the production of hbs antigen. the immunogenicity of the hbs antigen is retained. | 1976 | 64018 |
| effects of synthetic salmon calcitonin on gastric secretion and ulcer formation in conscious cats and rats. | in conscious and unrestrained cats the gastric secretion and ulcer formation induced by i.v. infusion of pentagastrin can be inhibited by synthetic salmon calcitonin given simultaneously. the volume and various constituents of gastric juice are proportionally diminished. pepsin alone is definitely more inhibited, which may be of significance in respect to the mode of action of calcitonin. these effects are dose dependent in the range of 0.01 mug - 1.0 mug/kg/h salmon calcitonin, corresponding to ... | 1976 | 64054 |
| calcitonin-biochemistry and physiology. | calcitonin is still a mysterious protein hormone. secreted by the c-cell in ultimobranchial body or thyroid glands, it seems to act as a hypocalcemic antagonist against parathyroid hormone by inhibiting osteolysis. this concept which was developed especially in small mammals like the rat, does not entirely fit the results gained from other species: in fish, ct levels change in connection with the reproductive cycle in the female, in amphibians, buffering capacity of the organism is bound to the ... | 1976 | 64055 |
| [gsp - a polypeptide of the pancreas with effect similar to gastrin]. | | 1976 | 64073 |
| the correlation between action potential duration and 42k-efflux in the hypoxic myocardium. | | 1976 | 64148 |
| affinity chromatography purification of pig heart and liver fumarase. | | 1976 | 64165 |
| [effect of atp on the reaction catalysed by fumarase]. | | 1976 | 64213 |
| inefficiency of complement action against self determinants: possible role for complement in (renal) allograft survival, pregnancy and tumor immunity. | | 1976 | 64231 |
| immunochemical study of beta-glucuronidase inhibitor from porcine sublingual gland. relationship between the antigenic determinant and the active site of the inhibitor. | following removal of sialic acid by neuraminidase treatment the activity of the beta-glucuronidase inhibitor was remarkably decreased, but the antigenic determinant was not affected. a partial common antigen to the inhibitor was isolated from porcine small intestine, by successive fractionation of trypsin extraction of the latter on sephadex g-150, deae-cellulose and sepharose 4b column chromatography. the immunologic and characteristic properties of the common antigen were compared with those o ... | 1976 | 64258 |
| modulation of the immune response by passive antibodies. iii. effects of igg1 and igg2 anti-carrier antibodies. | | 1976 | 64310 |
| maintenance of immunologic self-tolerance by nonimmunogenic forms of antigen. | immunologic tolerance to eae in guinea-pigs appears to be a function of a determinant distinct from the encephalitogenic region of the myelin basic protein molecule. in lewis rats (in which species the molecular sites for disease-induction and tolerance have not been completely characterized) the mechanism underlying this state of immunologic tolerance involves suppressor cell regulation of the autoimmune response. on the basis of these experimental findings we postulate that natural self-tolera ... | 1976 | 64328 |
| pregnancy zone protein analogue in pregnant and non-pregnant primates, and its decrease during pregnancy in some monkey species. | rabbit antiserum to human pregnancy zone protein (pzp) cross-reacted with analogous proteins in several species of primates. the chimpanzee pzp showed reactions of identity with human pzp, while the pzp analogue in the orangutan, in four species of old world monkeys (pig-tailed, rhesus, cynomolgus and stump-tailed) and in a species of new world monkey (squirrel) showed equivalent reactions of partial identity with human pzp. in the chimpanzee and orangutan, the pzp analogue was present in low co ... | 1976 | 64329 |