| role of vascular proliferation on angiographic appearance and encapsulation of experimental traumatic and metastatic brain abscesses. | experimental traumatic abscesses were produced in rhesus monkeys by intracerebral injection of nutrient agar contaminated with staphylococcus epidermidis, and metastatic abscesses were induced by intracarotid embolization of silicone cylinders contaminated with staphylococcus epidermidis. all monkeys underwent preoperative and serial postoperative carotid angiography. traumatic abscesses produced early capsular blushes and progressive anterior cerebral artery displacements. metastatic abscesses ... | 1978 | 415122 |
| serum amino acids during gestation of rhesus monkeys fed two different levels of protein. | | 1978 | 415124 |
| the visual pigments of rods and cones in the rhesus monkey, macaca mulatta. | 1. new microspectrophotometric measurements have been made of the photo-pigments of individual rods and cones from the retina of the rhesus monkey (macaca mulatta). the measuring beam was passed transversely through isolated outer segments. 2. the transverse absorbance for rods ranged from 0.02 to 0.04 and that for cones from 0.01 to 0.03. 3. the mean absorbance spectrum for rods (n = 25) had a peak of 502 +/- 2.7 nm. a digitonin extract from the same group of eyes gave a lambda-max. of 499 +/- ... | 1978 | 415133 |
| self-administration of heroin, acetylmethadol, morphine, and methadone in rhesus monkeys. | | 1978 | 415198 |
| ultradian rhythm of plasma noradrenaline in rhesus monkeys. | | 1978 | 415252 |
| gingival response to silk, cotton, and nylon suture materials. | silk, cotton, and nylon suture materials were implanted in the tunica propria of the gingiva in seven adult rhesus monkeys. the histologie study of twenty-four biopsy specimens indicated that there was neither an increase in the vascular permeability nor a leukocytic margination and migration into the tissues adjacent to the suture materials. however, there was a variable histiocytic reaction, with multinucleated cell formation. this reaction was quite intense with cotton, less intense with silk ... | 1978 | 415276 |
| cerebellar contribution to oculomotor function. | normal 38 juvenile rhesus monkeys were used to study cerebellar contribution to oculomotor function. (1) gaze nystagmus was seen only after bilateral flocculus lesions. (2) spontaneous nystagmus was observed after nodulus, flocculus and cerebellar nuclei lesions. (3) okn was severely impaired after bilateral flocculus and nodulus lesions. it was slightly impaired after dentate nucleus lesions in a long-term observation. (4) it is a very interesting finding that okn is severely impaired after des ... | 1977 | 415281 |
| anosmia in male rhesus monkeys does not alter copulatory activity with cycling females. | three adult male rhesus monkeys were tested daily with intact adult female partners over the course of four or five mentstrual cycles. the males were made permanently anosmic by chemical ablation of the olfactory epithelium after the second or fourth cycle was completed. all males continued to display typical cycles of copulation with their partners after the anosmia procedures, with the shortest latencies to ejaculation occurring during the periovulatory phase of the partner's ovulatory cycle. ... | 1978 | 415362 |
| toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rhesus monkeys (macaca mulatta) following a single oral dose. | | 1978 | 415382 |
| vasectomy in rhesus monkeys. iii. light microscopic studies of testicular morphology. | rhesus monkeys were randomly assigned to undergo various surgical procedures. the animals were followed from one to sixty-six weeks postvasectomy, at which time they were sacrificed and their tissues prepared for light and electron microscopy. vasectomy in the rhesus monkey, as in certain other species, appears to be a procedure not attended with widespread testicular atrophy or histologic evidence of impaired spermatogenic potential utilizing the procedures and postoperative periods studied. wh ... | 1978 | 415398 |
| plasmodium knowlesi malaria in the rhesus monkey. | twelve rhesus monkeys were inoculated intravenously with about 500 000 malaria parasites, plasmodium knowlesi. acute hemolysis occurred 5 days later, and all animals died on the 6th or 7th day after inoculation. all organs were gray-green to gray-brown because of deposition of hemoglobin and malaria pigments. this deposition was particularly striking in the lung, brain, abdominal fat and serous surfaces. microscopic changes indicative of acute hypoxia were found in the liver (centrilobular necro ... | 1978 | 415405 |
| a radioimmunoassay of oestrone in plasma. plasma levels of oestrone and oestradiol in oophorectomized rhesus monkeys during treatment with subcutaneous implants containing oestrone. | a highly specific antiserum to oestrone was used to develop a sensitive radioimmunoassay. plasma was generally analysed without prior separation of the oestrogens. a small amount of plasma (0.1-0.2 ml) was extracted once with diethyl ether. the above and previously described radioimmunoassays were used to estimate plasma levels of oestrogens in oophorectomized monkeys treated with subcutaneous oestrone implants. three monkeys received a rod containing 40 mg of oestrone. the rods were kept in pla ... | 1978 | 415474 |
| protein deprivation in primates. x. test performance of juveniles born of deprived mothers. | forty juvenile rhesus monkeys whose mothers were fed semisynthetic diets containing 13.4, 6.7, or 3.35% protein during pregnancy were tested as juveniles on four tests of perceptual-discrimination learning. all juveniles were well fed since birth. no significant differences in proficiency due to diet could be detected. it is concluded that thanks to the mother's proficient adaptation to the diet the fetus is well protected, and not deprived. | 1978 | 415589 |
| protein deprivation in primates. xi. determinants of weight change during and after pregnancy. | individual differences in weight gain of rhesus monkeys during pregnancy far exceed the variation in infant weight. weight gain thus reflects maternal adjustment to her physiological state in relation to her environment rather than growth of the infant. diets high in protein lead to great weight gain. skeletal length is positively correlated and conception weight negatively correlated with weight gain. season of pregnancy, length of gestation and sex of the infant are unrelated to weight gain. n ... | 1978 | 415590 |
| immunogenetic studies of rhesus monkeys. 8. a new reagent of the g blood group system and an example of the founder principle. | a new reagent called g-3' has been discovered which detects the product of the g3 allele, regardless of the other g allele in the genotype. with this new reagent we can delineate nine of 10 genotypes of the g blood group system. the explicit detection of g3 revealed an example of the founder principle in that the frequency of this allele between the feral and laboratory-reared monkeys was significantly different. | 1977 | 415641 |
| effect of staphylococcal enterotoxin b on cardiorenal functions in rhesus macaques. | selected cardiovascular and renal functions were measured for 5 hours in conscious, chair-restrained, female rhesus macaques (macaca mulatta) after iv (0.05 and 1.0 mg/kg) or oral (1.0 mg/kg) administration of staphylococcal enterotoxin b (seb). cardiovascular functions, renal hemodynamics, and renal metabolism were also studied between 6 and 11 hours after iv seb inoculation. oral seb produced few changes in cardiorenal functions. in contrast, iv seb produced hypotension, tachycardia, increased ... | 1978 | 415647 |
| [cellular composition of the lymph nodes of monkeys (rhesus macaque) under normal and experimental conditions]. | by means of mathematical methods, quantitative and qualitative changes were studied in different structural components of the mesenteric (ileocecal) lymph nodes in normal monkeys (macaca rhesus) and under per os administration of salmonella typhi murium, streptomycin-dependent. cellular composition was calculated in the cortical plateau, cortical (lymphoid) cords and in follicules. average percent of every cell type was determined. vaccine administration, was stated to inhibit cytopoiesis in the ... | 1978 | 415703 |
| experimental retinal vascular occlusion. i. pathogenesis of central retinal vein occlusion. | in 45 eyes of rhesus monkeys, five types of central retinal vascular occlusion were produced by lateral orbitotomy: group 1, central retinal vein occlusion (crvo) alone; group 2, crvo with simultaneous central retinal artery (cra) occlusion; group 3, crvo with transient clamping of the cra for either 2 to 2 1/2 hours (group 3a) or 6 to 7 1/2 hours (group 3b); and group 4, crvo with segmental retinal ischemia. the eyes were examined by fundus photography and fluorescein angiography for up to nine ... | 1978 | 415709 |
| ovulation induction by gonadotropin and prostaglandin treatments of rhesus monkeys and observations of the ova. | | 1978 | 415767 |
| functional development of the dorsolateral prefrontal cortex: an analysis utlizing reversible cryogenic depression. | the dorsolateral prefrontal cortex of rhesus monkeys was functionally inactivated by local hypothermia as the monkeys performed spatial delayed-response and spatial delayed-alternation tasks at different stages of postnatal development. cryogenic depression of prefrontal cortex at a temperature sufficient to induce 21--25% decrements in delayed-response performance in 34--36-month-old-monkeys, produced deficits of only 7--8% in 19--31-month-old and no detectable loss in younger monkeys, 9--16 mo ... | 1978 | 415802 |
| etiology of the negative chronotropic responses to transient coronary artery occlusion in the anesthetized rhesus monkey. | etiology of the negative chronotropic response to coronary artery occlusion was studied in chloralose-anesthetized monkeys. one-minute occlusion of the circumflex (circ) coronary artery resulted in marked negative chronotropic responses and consistent alterations in atrial electrograms. these responses were dependent on interruption of flow to a small proximal circ branch, and postmortem examination revealed that it perfused the sinus node region. the negative chronotropic response was not depen ... | 1978 | 415826 |
| adult male--infant interactions among monkeys living in nuclear families. | adult male rhesus monkeys were housed in nuclear families containing adult female mates, offspring, and other infants and adults. behaviors exhibited by the adult males were recorded 4 days per week over a 37-month period; in interactions involving other monkeys, the identity and the responses of those participants were also recorded. the results indicated that, although adult males were less active and more stable in their behavioral levels than mates or offspring, they clearly distributed both ... | 1977 | 415846 |
| comparative values of c3 in normal rhesus monkey and man. | | 1977 | 415972 |
| the qualitative evaluation of airway responses to immunologic and pharmacologic stimuli in rhesus monkeys. | this report describes the current status of a colony of rhesus monkeys composed of a group of animals with consistent asthmatic responses to ascaris antigen challenge, a variable group and a negative group. the cumulative experience with the consistent group of 5 animals totals 144 months of observation with 86 positive respiratory responses to 86 aerosol challenges. further studies compare rhesus airway responses to ascaris antigen, anti-ige, histamine, prostaglandin (pg)f2alpha, carbocholine, ... | 1978 | 416064 |
| pituitary-thyroid function in the rhesus monkey (macaca mulatta). | | 1978 | 416160 |
| regulation of thyrotrophin secretion by negative feedback of tri-iodothyronine on the hypothalamus. | bilateral injections of tri-iodothyronine (t3, 2 ng in 2 microliter artificial cerebrospinal fluid, csf) were made into the hypothalami of 15 hypothyroid rhesus monkeys (macaca mulatta) prepared with chronically implanted intrahypothalamic cannulae. in 29 out of 96 such injections, the concentration of thyrotrophin (tsh) in the plasma fell rapidly by more than 30% and returned to the basal value over the succeeding 48 h, in 13 experiments the fall was 20-30% and in the remaining 54 experiments t ... | 1978 | 416161 |
| experimental respiratory syncytial virus infection of four species of primates. | four species of nonhuman primates were inoculated intranasally with 10(3.1) to 10(3.7) plaque forming units (pfu) of respiratory syncytial (rs) virus. adults squirrel monkeys and newborn rhesus monkeys became infected and shed small quantities (peak titer 10(2.0) pfu/ml of nasopharyngeal swab specimen) of virus, but illness did not develop. infant cebus monkeys aged 2 months became infected, shed 10(2.3) to 10(3.8) pfu/ml of nasopharyngeal swab specimen, but did not become ill. chimpanzees aged ... | 1977 | 416176 |
| the reinforcing properties of procaine and d-amphetamine compared in rhesus monkeys. | twelve rhesus monkeys were studied under a fixed-ratio (fr) schedule of intravenous procaine or d-amphetamine injection from 8 a.m. to 4 p.m. daily. under the fr schedule, every nth lever press produced an injection. the fr value (n) and the dose per injection of procaine and d-amphetamine were varied systematically. at a fr value of 10, responding was maintained by doses of procaine ranging from 0.125 to 12 mg/kg/injection and by doses of d-amphetamine ranging from 0.01 to 0.1 mg/kg/injection. ... | 1978 | 416198 |
| development of a pulmonary technique to assess inhaled bronchoactive agents in the conscious rhesus monkey. | | 1978 | 416200 |
| effect of 1-(2,4-dichlorobenzyl)-indazole-3-carboxylic acid on sperm tails in rhesus monkeys. | large numbers of spermatozoa with bent or coiled tails were found in the ejaculates of rhesus monkeys treated with 1-(2,4-dichlorobenzyl-indazole-3-carboxylic acid (dica) (50 or 500 mg/kg for various periods). the defect appeared only in spermatozoa in the cauda epididymidis and consisted of axoneme disarrangement and loss of the fibre doublets. the coil was completely enclosed in a membrane. | 1978 | 416207 |
| effect of chronic oral methadone treatment on the growth of maturing monkeys. | three male rhesus monkeys drank methadone hydrochloride (1.0-2.5 mg/kg/day) in tang orange drink from age two to four years. their rate of body weight gain was faster than that found by other experimenters. in a second study one male monkey drank 2.0 mg/kg/day methadone while two others drank only tang from age 21/2 to 31/2 years. the rate of body weight gain was identical for the three monkeys, and was the same as that found in the previous study. the apparent augmentation of body weight gain i ... | 1977 | 416217 |
| pulmonary acariasis in an infant, colony-born rhesus monkey (macaca mulatta). | | 1978 | 416293 |
| acepromazine-ketamine anesthesia in the rhesus monkey (macaca mulatta). | six adult male rhesus monkeys (macaca mulatta) were anesthetized using a combination of acepromazine maleate and ketamine hydrochloride administered by intramuscular injection. this combination produced a smooth induction to anesthesia requiring less than 5 minutes. the average duration of anesthesia was slightly less than 1 hour and was safely prolonged with additional doses of ketamine. the depth of anesthesia was sufficient for minor surgical procedures and for precise radiological studies. n ... | 1978 | 416295 |
| the handedness of rhesus monkeys--i. distribution. | | 1978 | 416370 |
| comparative xenodiagnosis with three triatomine species of different hosts with natural and experimental chronic infections with trypanosoma (schizotrypanum) cruzi. | simultaneous xenodiagnosis was made of 29 patients with chronic chagas's disease, six naturally infected opossums (didelphis azarae) and of a rhesus monkey with an experimental chronic infection with trypanosoma (schizotrypanum) cruzi (peru strain). patients and opossums were from an endemic area in the state of bahia, brazil, where panstrongylus megistus is the sole domiciliary vector of the disease to man. various instars of p. megistus triatoma infestans and rhodnius prolixus were used. the p ... | 1978 | 416525 |
| attempts to induce immunological enhancement for kidney allografts in rhesus monkeys. | various rhesus alloantisera were tested for their capacity to induce enhancement of kidney allograft survival in d locus-incompatible rhesus monkeys. six experimental groups were investigated: 1, ten allografted monkeys remained untreated; 2, six recipients were treated with imuran and prednisolone; 3, eight rhesus monkeys were treated with a polyspecific "anti-sd" serum; 4, four animals were given oligospecific antikidney serum; 5, four monkeys were treated with oligospecific antiblood serum; a ... | 1978 | 416527 |
| the rhesus monkey as a preclinical model for bone marrow transplantation. | | 1978 | 416528 |
| transfer of 51cr platelets and 51chromium ions across the term rhesus monkey placenta. | | 1978 | 416645 |
| disruption of blood-retinal barrier at the retinal pigment epithelium after systemic urea injection. | electron microscopic studies were done on the structural alterations of retinal pigment epithelial cells occurring under osmotic stress utilizing rhesus monkeys and lanthanum nitrate as a tracer. fluorescein fundus angiography revealed leaking points of fluorescein from the choroid to the retina, and various degenerative alterations of the retinal pigment epithelial cells were observed in these leaking areas. some cells included many vacuoles in their cytoplasm, but diffusion of lanthanum from t ... | 1978 | 416648 |
| temporal relationships of estrogen, progesterone, and luteinizing hormone levels to ovulation in women and infrahuman primates. | these studies were undertaken to ascertain the interval between the estrogen and lh peaks and ovulation in women, rhesus monkeys, and baboons. estrogen, progesterone, and lh were measured by ria. ovulation was documented by visual examination of the ovaries, histology of the corpora lutea, and recovery of ova. the data for human subjects was based on a group of 23 normal women scheduled for surgical sterilization. blood was drawn daily between 8:30 and 10:30 p.m. beginning on day 10 of the cycle ... | 1978 | 416719 |
| the reversible biotransformation of n-acetylprocainamide in the rhesus monkey. | the specific activity of 14c-n-acetylprocainamide (14c-napa) was measured in the 24-h urine of two rhesus monkeys given the labelled drug i.v. specific activity was found to decrease by 15.8% from the original value. this was attributed to an in vivo biotransformation of napa to procainamide (pca) and reacetylation of pca back to napa before it was eliminated in the urine. the major fraction of napa, 72.1% of the dose, was found to be excreted in the urine of monkeys in 48 h. | 1978 | 416831 |
| projections of lateral orbital cortex to sensory relay nuclei in the rhesus monkey. | | 1978 | 416882 |
| an autoradiographic, semistereotaxic mapping of major projections from locus coeruleus and adjacent nuclei in macaca mulatta. | the autoradiographic method was used to trace projections from the monkey locus coeruleus (lc) and adjacent nuclei (nn. parabrachiales, n. tractus mesencephalicus nervus trigemini, substantia grisea centralis). pathways attributed to lc are presented diagrammatically in a set of 26 coronal sections. they include a descending pathway along the tractus tegmentalis centralis, a caudal pathway entering the corpus medullaris cerebellaris via the lateral wall and roof of ventriculus quartus, and an as ... | 1978 | 416887 |
| intensity of stimulation and rod and cone response in clinical electroretinography. | we exposed adult rhesus monkeys who were fully dark adapted to paired flashes of white light which increased in intensity by increments of 0.1 log. units. as intensity increased, the amplitudes of both the cone and rod systems increased while the implicit times decreased so that the responses overlapped. high intensities produce a complex waveform which prevents separation of the rod and cone components or timing of the peaks. on the other hand, low intensities separate the early and late recept ... | 1978 | 416893 |
| radioimmunoassay of calcitonin in the plasma of rhesus monkey and man. | we describe a radioimmunoassay for rhesus monkey and human immunoreactive calcitonin, in which a selected goat anti-human calcitonin antiserum, 131i-labeled synthetic human calcitonin tracer, and purified synthetic human calcitonin standards were used. the mean basal concentration of calcitonin in normal monkey plasma (254 microgram/liter) was not significantly different from that in normal human plasma (217 microgram/liter). the data indicate that the method is sensitive (lower limit of detecti ... | 1978 | 416924 |
| endocrine regulation of fetal development and its relation to parturition in the rhesus monkey. | rhesus monkey fetuses were surgically prosencephalectomized (type 2) or functionally hypophysectomized (type 1) at 75 days gestation, then returned to the uterus until elective caesarean section on day 145--150 (term 167 days). deprivation of fetal hypothalamic releasing factors in type 2 and fetal pituitary tropic hormones in type 1 significantly delayed the ontogeny and functional development of fetal endocrine tissues. bone ossification and growth were significantly retarded in type 1 only, n ... | 1977 | 416938 |
| distribution of calcitonin cells in the thyroid glands of normal adult rhesus monkey macaca mulatta. | the calcitonin cells of adult rhesus monkey macaca mulatta are located in the central region of thyroid along the median axis. the anterior and posterior poles, the isthmus and peripheral regions of thyroid are completely devoid of c cells. the parathyroid also lacks c cells. | 1978 | 416967 |
| primate mesenteric blood flow. effects of vasopressin and its route of delivery. | the effects of vasopressin on blood flow in the superior mesenteric artery and on mean arterial pressure and portal venous pressure were measured in 7 rhesus monkeys. vasopressin was injected, as either a bolus, or infused both intravenously and intraarterially to assess the influence of the route of administration upon hemodynamic responses. dose-dependent decreases in superior mesenteric arterial flow were observed during both intraarterial and intravenous injections of vasopressin. no statist ... | 1978 | 416990 |
| effects of estradiol benzoate, estrone, and propionates of testosterone or dihydrotestosterone on sexual and related behaviors of ovariectomized rhesus monkeys. | | 1977 | 417014 |
| behaviorial effects of a synthetic mixture of aliphatic acids in rhesus monkeys (macaca mulatta). | | 1977 | 417015 |
| the rate of reflux fluid movement into the eye from schlemm's canal during hypotony in the rhesus monkey. | | 1978 | 417043 |
| perfusate effects upon resistance to aqueous humor outflow in the rhesus monkey eye. a comparison of glutathione-bicarbonate ringer's solution to pooled aqueous humor as perfusate. | in vivo perfusion of the anterior chamber of normal rhesus monkeys with pooled rhesus aqueous humor gives an initial total facility of 0.48 +/- 0.08 (+/-s.e.) microliter/min/mm hg. with continued intermittent perfusion for 2 hr this value increased only slightly to 0.57 +/- 0.10 microliter/min/mm hg. perfusion of the paired eyes of the same monkeys with glutathionebicarbonate ringer's solution gives an initial total facility of 0.55 +/- 0.08 microliter/min/mm hg. this value increased to 1.21 +/- ... | 1978 | 417044 |
| static lung mechanics of intact and excised rhesus monkey lungs and lobes. | subdivisions of lung volume and pressure-volume (pv) curves of the lung and chest wall (cw) were measured in 12 rhesus monkeys (macacca mulatta) under pentobarbital anesthesia. in addition, volumes and pv curves were obtained on the excised lungs and lobes of 12 cynomolgus monkeys (m. fasicularis). boyle's law was used to determine functional residual capacity (frc) in the intact animals and water displacement to determine minimal volume (mv) in the excised lungs. total lung capacity (tlc = lung ... | 1978 | 417053 |
| viremia and serum antibodies in macacus rhesus monkey after inapparent infection with european tick-borne encephalitis virus. | 1. inapparent infection was called forth in m. rhesus monkeys by means of subcutaneous inoculation of etbe virus. 2. viremia was found in 18 (86 per cent) of 21 monkeys. in all the 18 monkeys, specific virus-neutralizing antibodies were found; in 17 of them complement-fixing antibodies developed in addition. 3. neutralizing antibodies (n greater than or equal to 1.7 log10) were first recorded on 10th day with a peak on 32nd day, retaining, after a small decrease, a relatively high level in all r ... | 1977 | 417136 |
| effect of peroral administration of xylitol on exocrine secretions of monkeys. | the effects of the administration of xylitol on the biochemical properties of monkey parotid and submandibular saliva and lacrimal fluid were investigated. monkeys (macaca mulatta) were fed either a sucrose or xylitol diet for 3 days. ingestion of xylitol was associated with a significant increase of the activity of the salivary lactoperoxidase. the concentration of protein was also increased. higher lactoperoxidase activity was found in parotid than in submandibular saliva. the concentrations o ... | 1978 | 417156 |
| pharmacokinetic profile of clonazepam in rhesus monkeys. | | 1978 | 417166 |
| meta substituted n-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships. | | 1978 | 417172 |
| the effects of diazepam, morphine and lidocaine on nociception in rhesus monkeys: a signal detection analysis. | | 1978 | 417174 |
| effect of ethynodiol diacetate with ethinyl estradiol on the mammary glands of rhesus monkeys: a preliminary report. | the oral contraceptive combination of ethynodiol diacetate with ethinyl estradiol (demulen) was given cyclically to 48 female rhesus monkeys for 5 years. doses employed were 1, 10, and 50 times the human dose. treatment did not induce palpable breast nodules, and there were no deaths from mammary gland cancer. | 1978 | 417188 |
| the effect of arachidonic acid on airway responses of rhesus monkeys. | | 1978 | 417227 |
| increased production of triglyceride-rich lipoproteins after partial biliary diversion in the rhesus monkey. | an interrelationship between bile acid and triglyceride metabolism is suggested by observations in patients with endogenous hypertriglyceridemia and in subjects treated with bile acid-binding resins or chenodeoxycholic acid. we investigated this possible interrelationship in the rhesus monkey. the effect of 14 days of partial bile diversion on plasma concentration and secretion rates of triglyceride-rich lipoproteins was studied by means of a stream-splitting device that permitted controlled int ... | 1978 | 417230 |
| bone marrow and lymphocyte cytogenetics of rhesus monkeys (macaca mulatta) treated with the clastogen mitomycin c. | rhesus monkeys (macaca mulatta) were used to determine their effectiveness as experimental animals for different cytogenetic tests with mitomycin c (mc). the micronucleus test (mnt and/or chromosome analysis of blood and bone marrow were made before and/or after the treatment with mitomycin c. thus, the controls data and treated data were obtained from the same animals. with the employed methology, the micronucleus test could not be performed on living animals. less chromosomal damage was detect ... | 1978 | 417245 |
| host-mediated assay in rhesus monkey (macaca mulatta): mutagenicity of mitomycin c. | | 1978 | 417246 |
| a study on the use of fluoroalkyl cyanoacrylate adhesive as a hemostatic agent and dressing after exodontia. | a fluoroalkyl cyanoacrylate is shown to be a very effective hemostatic agent in routine extractions in rhesus monkeys. clinical and histologic observations of the healing sockets at selected intervals revealed uneventful healing, even when the tissue adhesive was placed directly against the alveolar bone within the extraction socket. the quantity, quality, and rate of bone replacement were not different between the experimental and control groups. when polymerized cyanoacrylate is entrapped with ... | 1978 | 417279 |
| antipyrine plasma half-life. in vivo indicator of oxidative metabolic capability in rhesus monkeys (macaca mulatta). | antipyrine plasma half-life (aph) has been used as an indicator of hepatic oxidase activity in rhesus monkeys (macaca mulatta). plasma disappearance of 14ch3-n-antipyrine (ap) was measured radiometrically. ap and 3 metabolites were detected using high pressure liquid chromatography. aph was assessed during a 300-day control period and following phenobarbital (pb) pretreatments. significant interindividual variability was observed requiring that animals be used as their own controls. pb (15 mg/kg ... | 1978 | 417345 |
| effects of group size, composition, introduction technique and cage apparatus on aggression during group formations in rhesus monkeys. | | 1978 | 417359 |
| potency in male rhesus monkeys: effects of continuously receptive females. | ejaculations decreased and mount latencies increased when intact males were paired regularly over a 3.5-year period (3180 tests) with ovariectomized females made constantly receptive by daily injections of estradiol. the deterioration in potency was abruptly and completely reversed by substituting a group of new but similarly treated females for the original ones. | 1978 | 417398 |
| preservation of platelet number and function with prostaglandin e1 during total cardiopulmonary bypass in rhesus monkeys. | | 1978 | 417415 |
| the major histocompatibility complex of rhesus monkeys. viii. isolation and partial characterization of sd antigens. | the structure and chemical nature of the serologically defined (sd) antigens coded by the major histocompatibility complex (rhla) of rhesus monkeys was studied. the use of specific anti-sd sera allowed the selective isolation of the corresponding antigens from crude antigen preparations. these were obtained by detergent solubilization after incorporation of 3h, 35s, and 14c amino acids in lymphocytes or mitogen-stimulated lymphoblasts. the results indicate that the sd antigens are of proteinaceo ... | 1978 | 417437 |
| t cell-specific activity in rabbit anti-human thymocyte globulin. correlation with immunosuppresive activity in nonhuman primates. | spotaneous e rosette-forming (t) lymphocytes were monitored in the peripheral blood of rhesus monkeys receiving a 5-day course of rabbit anti-human thymocyte globulin (ratg) after skin allotransplantation. mean graft survival in ratg-treated recipients was 32.3 +/- 7.6 (sd) days compared with 8.2 +/- 1.7 (sd) days in controls. the percentage and total number of circulating t cells fell precipitously after ratg treatment and recovered slowly. linear regression analysis showed that the recovery pa ... | 1978 | 417439 |
| effects of indomethacin on labor, fetal oxygenation, and fetal development in rhesus monkeys. | | 1978 | 417573 |
| zinc deficiency in pregnant rhesus monkeys: effects on behavior of infants. | zinc deprivation from day 110 to 150 of gestation in rhesus monkeys resulted in rash, alopecia, anorexia, decreased feed efficiency, and low plasma zinc in the mothers. infants of the dams that had been deprived of zinc during gestation displayed a more rapid postnatal growth rate than infants of the control mothers. infants of the zinc-deprived dams played and explored less than the control infants. they also associated with their mothers a greater percentage of the time and were less active. t ... | 1978 | 417617 |
| the effects of phenylethylamine in rhesus monkeys. | in controlled experiments rhesus monkeys that had received phenylethylamine (pea) demonstrated behavior similar to that reported after the administration of amphetamines, except that tolerance to pea did not develop. these findings are of psychiatric interest because pea is found in the human body and is a specific substrate for type b mao, which is found in decreased quantities in certain schizophrenic patients. | 1978 | 417638 |
| reciprocal changes in primary and secondary optokinetic after-nystagmus (okan) produced by repetitive optokinetic stimulation in the monkey. | in six rhesus monkeys (macaca mulatta) the effect of repetitive periods of whole-field optokinetic stimulation upon the different phases of optokinetic after-nystagmus (okan) was studied. the precedings optokinetic stimulus consisted of rotating a striped cylinder around the stationary monkey. experiments were performed on up to 8 successive days. the results demonstrate that okan i and okan ii are affected in a reverse manner by repeated optokinetic stimulation: the duration of okan i strongly ... | 1978 | 417698 |
| troponin i from human skeletal and cardiac muscles. | 1. myofibrils from human skeletal muscle contained regulatory proteins exhibiting similar electrophoretic behaviour to those present in rabbit skeletal muscle. 2. all human skeletal muscles examined contained two forms of troponin i corresponding to the forms already characterized in fast and slow rabbit muscle. 3. the ratios of the amounts of the two forms of troponin i in different human skeletal muscles were not identical with the ratios for the type 1 to type 2 fibres published in the litera ... | 1978 | 417726 |
| the effects of bilateral frontal eye-field, posterior parietal or superior collicular lesions on visual search in the rhesus monkeys. | superior collicular, frontal eye-field and posterior parietal lesions increased the time taken to find a circular target among other geometrical shapes. the collicular monkeys were considerably more impaired than the other groups, suggesting that the superior colliculus is the main neural structure underlying this highly practised visual search task. failure to respond in the 5 sec allowed on each trail increased for all groups, and the collicular and frontal groups showed a small increase in fa ... | 1978 | 417756 |
| the effects of bilateral frontal eye-field lesions on the learning of a visual search task by rhesus monkeys. | | 1978 | 417761 |
| use of pneumoencephalography to increase stereotaxic accuracy in rhesus monkeys. | a radiographic method for visualizing intracranial structures for stereotaxic surgery is described. the procedure circumvents the problems associated with the use of radiopaque dyes, and it does not require modification of standard stereotaxic equipment. anatomical data derived from the use of the method are presented, as well as an example of its application for accurately placing cannulae in the midbrain. | 1978 | 417763 |
| cortical neurons projecting to the cervical and lumbar enlargements of the spinal cord in young and adult rhesus monkeys. | | 1978 | 417943 |
| long-term safety evaluation of 3-phenyl-5beta diethylaminoethyl-1,2,4-oxadiazole. ii. in rhesus monkeys. | | 1978 | 417944 |
| effect of ambient temperature on development of prostaglandin e1 hyperthermia in the rhesus monkey. | prostaglandin e1 (pge1) hyperthermia (fever) was studied at ambient temperatures (ta) of 18, 27, and 35 degrees c in four male unanesthetized rhesus monkeys (macaca mulatta) implanted with four guide tubes and one reentrant tube within the preoptic anterior hypothalamus (po/ah). rectal, hypothalamic, and mean weighted skin temperatures, o2 consumption, co2 production, and respiratory and total evaporative water losses were measured continuously before and during pge1 fever at each ta. the febril ... | 1978 | 418051 |
| an ultrastructural study of preimplantation uterine embryos of the rhesus monkey. | two cleavage stage embryos, two blastocyts surrounded by zona pellucida, and two azonal ('hatched') blastocysts were recovered from uteri of rhesus monkeys and examined with the electron microscope. cleavage-stage embryos showed no striking differences between inside and outside blastomeres, all of them displaying primitive junctional complexes, heteromorphic mitochondria, large ovoid nuclei and a few polyribosomes. the zonal blastocysts had distinctive trophectoderm and inner cell mass areas in ... | 1978 | 418052 |
| high-performance liquid chromatographic determination of plasma and urinary 1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3,7-dicarboxylic acid. | a high-performance liquid chromatographic method for the analysis of 1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3,7-dicarboxylic acid (i) in plasma and urine is described. a statistical evaluation of the assay technique has shown acceptable accuracy and precision at concentrations as high as 2.0 microgram/ml of plasma or 29.0 microgram/ml of urine for samples augmented with 1. as little as 0.08 microgram/ml of i in plasma or 0.42 microgram/ml of i in urine were quantitatively determined. the me ... | 1978 | 418076 |
| thalamic projections to s-i in macaque monkey. | the organization of thalamic input to functionally characterized zones in primary somatosensory cerebral cortex (s-i) of macaque monkeys (macaca mulatta) was investigated using the method of labelling by retrograde transport of horseradish peroxidase (hrp). it was found that the cell columns positioned at the posterior margin of the band of cortex representing a given body region receive thalamic input from a posterior level of the ventroposterior thalamic nucleus (vp), and that cell columns at ... | 1978 | 418081 |
| efferent projections of the subthalamic nucleus: an autoradiographic study in monkey and cat. | the efferent projections of the subthalamic nucleus were studied with the autoradiographic tracing technique in rhesus monkey and cat. from the data it appears that the major efferent projections of the nucleus are to the pallidal complex and the substantia nigra. in both monkey and cat, the projection to the pallidal complex is truly massive and is directed at both pallidal segments. the projection field includes an infracommissural part of the pallidal complex bordering on the substantia innom ... | 1978 | 418083 |
| the neurons and the synaptic endings in the primate basilar pontine gray. | two types of neurons, projection and intrinsic, previously identified in golgi preparations of the adult monkey (macaca mulatta) basilar pontine gray (cooper and fox, '76) were observed electronmicroscopically in macaca mulatta and the squirrel monkey saimiri sciureus. the cell body of the projection neuron measures up to 37 micrometer and its cytoplasm is rich in organelles. the goli apparatus, ribosomes, and mitochondria are disposed around the nucleus, while rough endoplasmic reticulum though ... | 1978 | 418084 |
| distribution of 14c-formaldehyde after pulpotomy with formocresol. | pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14c-formaldehyde into the systemic circulation after formocresol pulpotomies. five-minute exposure of pulpal tissue to the 14c-formocresol resulted in the systemic absorption of approximately 1% of the dose. two hours of exposure of pulp tissue to the 14c-formocresol did not increase the systemic absorption. multiple sequential pulpotomies resulted in proportionately higher systemic absorptio ... | 1978 | 418090 |
| the topographic organization of rhesus monkey prestriate cortex. | 1. the topographic organization of prestriate visual cortex in the rhesus monkey has been studied both anatomically, by determining the pattern of termination of fibres passing through the corpus callosum, and physiologically, in the same animals, by plotting receptive field positions for different recording sites. results are displayed on two-dimensional, "unfolded" maps of the cortex in the dorsal half of the occipital lobe. 2. transcallosal fibres terminate in a narrow strip of cortex along t ... | 1978 | 418173 |
| the cortical projections of foveal striate cortex in the rhesus monkey. | 1. the cortical projections of the foveal and extrafoveal parts of the striate cortex have been compared, using conventional degeneration techniques, as well as combinations of anatomical methods. while both foveal and extrafoveal striate cortex share a common pattern of projections (to areas v2, v3 and the visual area in the medial part of the posterior bank of the superior temporal sulcus), foveal striate cortex was found to have an additional projection (to part of the cortex of the fourth vi ... | 1978 | 418174 |
| the third visual complex of rhesus monkey prestriate cortex. | 1. two independent but neighbouring visual areas, v3 and v3a, sharing a common cytoarchitectural plan, but in each one of which the visual fields are separately represented, have been studied anatomically, functionally, and in combined anatomico-physiological experiments. 2. the properties of single cells in the two areas are so similar, judged by the techniques used in this study, that it is often impossible to tell whether any one penetration was sampling from cells in v3 or v3a. this is espec ... | 1978 | 418175 |
| uniformity and diversity of structure and function in rhesus monkey prestriate visual cortex. | 1. recordings were made from single neurones, or small clusters of cells, in five prestriate visual areas of rhesus monkey cortex. the cells were studied for their binocularity, as well as for their orientational, motion and colour preferences. in all, 1500 cells were studied, 250 cells for each of the areas v2, v3, v3a and the motion area of the posterior bank of the superior temporal sulcus, and 500 cells for v4. all the cells referred to in this study can be placed in one prestriate area or a ... | 1978 | 418176 |
| narcotic tolerance and operant behavior. | narcotic tolerance was measured as a shift to the right in dose-effect relations on operant behavior following repeated administration of drug. tolerance has been observed with operant responding in both pigeons and rhesus monkeys. the amount of tolerance observed with food-reinforced responding is related both to the amount of morphine administered and to the nature of the drug-induced change in operant responding. pharmacological specificity of the narcotic tolerance has been confirmed by equi ... | 1978 | 418354 |
| ethanol drinking by rhesus monkeys as a function of concentration. | ethanol deliveries maintained fixed-ratio (fr) responding of three rhesus monkeys during daily 3-h sessions. at fr values of 8 or 16, ethanol concentration was varied in the sequence 0 (water), 8, 11.3, 16, 22.6 32, 8, and 0% (w/v). as the ethanol concentration increased, number of liquid deliveries decreased somewhat. blood ethanol levels were usually greater than 200 mg% and occasionally greater than 300 mg%. | 1978 | 418445 |
| [dosage relationship of the yield of chromosome aberrations at various times of fixation of primary monkey kidney cultures (macaca mulatta)]. | | 1978 | 418463 |
| the toxicity of 1-amino-3-chloro-2-propanol hydrochloride (cl88,236) in the rhesus monkey. | the toxicity of 1-amino-3-chloro-2-propanol is associated with acute histopathological change in the medulla oblongata, characterised lesions of focal oedema. continued administration results in neurological scars. lesions can be induced at dose levels of 50 mg . kg-1 day-1. clinical manifestations of neurological involvement are periods of slight incoordination and loss of balance in a few animals only. | 1978 | 418534 |
| disposition and metabolism of benoxaprofen in laboratory animals and man. | 1. the absorption, distribution, metabolism and excretion of benoxaprofen, a novel anti-inflammatory compound, has been studied in the dog, mouse, rat, rabbit, rhesus monkey and man. 2. benoxaprofen was well absorbed after oral administration of doses of 1 to 10 mg/kg in all six species. only unchanged drug was detected in plasma. it was extensively bound to plasma proteins, the highest binding occurring in man (99.8%) and rhesus monkey (99.6%). 3. species differences were observed in the plasma ... | 1978 | 418580 |
| [interaction between the prefrontal cortex and hippocampus of monkeys in delayed spatial choice]. | interaction between bioelectrical processes in the prefrontal cortex and the hippocampus was investigated on three macaca mulatta performing a task of delayed spatial choice. it was found that the processes of short-term spatial memory are reflected in certain patterns of reciprocal correlations between eeg of the given structures. different patterns correspond to tasks of different nature. the data obtained corroborate the hypothesis that the functional significance of brain structures may chan ... | 1978 | 418597 |
| [electrophysiologic study of hypothalamo-neocortical connections in macaca mulatta monkeys]. | in acute experiments on monkeys studies have been made on the character and functional properties of the ep as well as of extracellular neuronal reactions in the new cortex zones during stimulation of phylogenetically different parts of the hypothalamus. it was shown that most short-latency, low-threshold ep and neuronal responses in the new cortex of the monkeys are recorded during stimulation of the posterior and lateral hypothalamus. it was also demonstrated that the focus of maximum activity ... | 1978 | 418607 |
| [participation of the frontal lobes in the integrative activity of the brain in macaca mulatta monkeys]. | frontal lobe neuronal impulsation during complex behavioral program was investigated by means of the multineuronal recording technique. this program consisted of unspecific expectation after the anticipatory stimulus, conditioned stimulus and delay period, trigger signal and alternative selection followed by food award. such processes as combining the external stimuli into the integrated program, preservation of short term memory traces, correct and incorrect experimental task solution are refle ... | 1978 | 418608 |
| [vasculature of the optic disc of a rhesus monkey (author's transl)]. | | 1977 | 418630 |