| seroepidemiology of spotted fever rickettsiosis in uttar pradesh: a prospective study. | spotted fever rickettsiosis (sfr), an acute febrile illness caused by rickettsia rickettsii, r. conorii and r. akari which is associated with considerable morbidity and mortality. sfr is one of the most covert emerging infections of the present time which is prevalent in various parts of india as shown by the increase in the number of clinically diagnosed patients in various states except uttar pradesh. | 2017 | 28764157 |
| ehrlichia canis and rickettsia spp. in dogs from urban areas in paraiba state, northeastern brazil. | the aims of our study was to identify ehrlichia canis and antibodies against rickettsia spp. belonging to the spotted fever group (sfg) in dogs sampled from paraiba state, northeastern brazil. blood and serum samples collected by convenience from dogs in urban areas of five municipalities were analyzed by real-time pcr for the detection of e. canis dna and by immunofluorescence assay test (ifat) for the identification of antibodies against rickettsia rickettsii, r. felis, r. parkeri, r. amblyomm ... | 2017 | 28658415 |
| rickettsia rickettsii infecting rhipicephalus sanguineus sensu lato (latreille 1806), in high altitude atlantic forest fragments, ceara state, brazil. | in brazil, spotted fever (sf) is caused by rickettsia rickettsii and rickettsia parkeri strain atlantic forest. in recent years, several human cases of a milder sf have been reported from the maciço de baturité region of ceará state. previous studies in this region found r. parkeri strain atlantic forest to be present in rhipicephalus sanguineus sensu lato and amblyomma ovale ticks. the present study isolated and identified the rickettsia spp. present in this new endemic area in brazil. in march ... | 2017 | 28535905 |
| evaluation of changes to the rickettsia rickettsii transcriptome during mammalian infection. | the lifecycle of rickettsia rickettsii includes infection of both mammalian and arthropod hosts, with each environment presenting distinct challenges to survival. as such, these pathogens likely have distinctive transcriptional strategies for infection of each host. herein, we report the utilization of next generation sequencing (rnaseq) and bioinformatic analysis techniques to examine the global transcriptional profile of r. rickettsii within an infected animal, and to compare that data to tran ... | 2017 | 28832688 |
| efficacy of sarolaner (simparic™) against induced infestations of amblyomma cajennense on dogs. | amblyomma cajennense is the main vector of rickettsia rickettsii which causes brazilian spotted fever. this adult tick preferably infests horses and capybaras, but has low host specificity during its immature stages, thus posing a threat to humans and dogs. in this study, the efficacy of sarolaner (simparic™/simparica®, zoetis) when administered once orally to dogs at 2 mg/kg was evaluated against induced infestations of a. cajennense nymphs for up to 35 days after treatment. | 2017 | 28814323 |
| rocky mountain spotted fever and pregnancy: four cases from sonora, mexico. | we present a series of four pregnant women with rocky mountain spotted fever (rmsf) that occurred in sonora, mexico, during 2015-2016. confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of rickettsia rickettsii by using an indirect immunofluorescence antibody assay. each patient presented with fever and petechial rash and was treated successfully with doxycycline. each of the women and one full-term infant delivered at 36 weeks gestation survived ... | 2017 | 28722584 |
| microrna signature of human microvascular endothelium infected with rickettsia rickettsii. | micrornas (mirnas) mediate gene silencing by destabilization and/or translational repression of target mrna. infection of human microvascular endothelial cells as primary targets of rickettsiarickettsii, the etiologic agent of rocky mountain spotted fever, triggers host responses appertaining to alterations in cellular gene expression. microarray-based profiling of endothelial cells infected with r.rickettsii for 3 or 24 h revealed differential expression of 33 mirnas, of which mirnas129-5p, 200 ... | 2017 | 28698491 |
| transmission dynamics and control of rickettsia rickettsii in populations of hydrochoerus hydrochaeris and amblyomma sculptum. | brazilian spotted fever (bsf), caused by the bacterium rickettsia rickettsii, is the tick-borne disease that generates the largest number of human deaths in the world. in brazil, the current increase of bsf human cases has been associated with the presence and expansion of capybaras hydrochoerus hydrochaeris, which act as primary hosts for the tick amblyomma sculptum, vector of the r. rickettsii in this area. | 2017 | 28582429 |
| the distinct transcriptional response of the midgut of amblyomma sculptum and amblyomma aureolatum ticks to rickettsia rickettsii correlates to their differences in susceptibility to infection. | rickettsia rickettsii is a tick-borne obligate intracellular bacterium that causes rocky mountain spotted fever (rmsf). in brazil, two species of ticks in the genus amblyomma, a. sculptum and a. aureolatum, are incriminated as vectors of this bacterium. importantly, these two species present remarkable differences in susceptibility to r. rickettsii infection, where a. aureolatum is more susceptible than a. sculptum. in the current study, a. aureolatum and a. sculptum ticks were fed on suitable h ... | 2017 | 28503490 |
| vector competence of amblyomma americanum (acari: ixodidae) for rickettsia rickettsii. | rickettsia rickettsii - the etiologic agent of rocky mountain spotted fever (rmsf) - is widely spread across the americas. in the us, dermacentor spp. ticks are identified as primary vectors of r. rickettsii and rhipicephalus sanguineus s.l. has been implicated in transmission of this pathogen in several locations in the southwest. conversely, ticks of the genus amblyomma are recognized vectors of rmsf in central and south america, but not in the us. a. americanum is one of the most aggressive h ... | 2017 | 28433728 |