| clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature. | to present a clinicocytopathologic correlation of an atypical case of cat scratch disease (csd) involving retroperitoneal lymph nodes, with emphasis on communication between service teams for managing lymphadenopathy of unknown origin. we consider clinical and cytologic differential diagnoses and review the literature on atypical cases of csd, with emphasis on abdominal presentation and cytologic findings. | 2015 | 25873511 |
| [an exceptional case of tricuspid infective endocarditis due to bartonella henseale revealed by an old pulmonary embolism]. | we report a case of blood culture-negative tricuspid infective endocarditis revealed after tick bite by repeated pulmonary infection during one year due to septic pulmonary emboli in a 67-year-old farmer woman. tricuspid vegetation and pulmonary emboli are calcified. lyme serology is negative. serologic test and pcr analysis are positive to bartonella henselae. the evolution is favorable after antibiotic and anticoagulant treatment. infective endocarditis due to b. henselae is an exceptional com ... | 2016 | 25869466 |
| reprogramming of myeloid angiogenic cells by bartonella henselae leads to microenvironmental regulation of pathological angiogenesis. | the contribution of myeloid cells to tumour microenvironments is a decisive factor in cancer progression. tumour-associated macrophages (tams) mediate tumour invasion and angiogenesis through matrix remodelling, immune modulation and release of pro-angiogenic cytokines. nothing is known about how pathogenic bacteria affect myeloid cells in these processes. here we show that bartonella henselae, a bacterial pathogen causing vasculoproliferative diseases (bacillary angiomatosis), reprogrammes huma ... | 2015 | 25857345 |
| touch not the cat bot a glove*: anca-positive pauci-immune necrotizing glomerulonephritis secondary to bartonella henselae. | a 36-year-old male presented with a secondary, but anti-neutrophil cytoplasmic antibody (anca) (proteinase-3) positive, vasculitis with renal insufficiency due to a pauci-immune necrotizing glomerulonephritis. an infective process was initially excluded by blood cultures and an echocardiogram prior to immunosuppression. the patient's condition failed to improve and re-evaluation confirmed infective endocarditis requiring valve replacement. subsequent tissue cultures identified bartonella hensela ... | 2014 | 25852867 |
| cat-scratch disease presenting as a solitary splenic abscess in an elderly man. | patients with cat-scratch disease (csd), which is caused by bartonella henselae, typically present with local lymphadenopathy with a brief period of fever and general symptoms. most cases are self-limiting and usually afflict children and young adults. although rare, csd can lead to serious complications, especially in immunocompromised patients. these rare complications often require intensive treatment. we describe the case of a 79-year-old man who presented with general malaise and a high fev ... | 2015 | 25804947 |
| bartonella henselae infection-associated vasculitis and crescentic glomerulonephritis leading to renal allograft loss. | bartonella henselae (bh) is the main cause of cat scratch disease (csd), which more typically presents as a self-limited localized suppurative lymphadenopathy in immunocompetent individuals. in contrast, immunocompromised patients commonly have systemic disease with life-threatening complications. in addition to the angioproliferative lesions, such as bacillary angiomatosis, an increasing number of immune post-infectious complications are being recognized with bh infections, including glomerulon ... | 2015 | 25753276 |
| infection with bartonella henselae in a danish family. | bartonella species constitute emerging, vector-borne, intravascular pathogens that produce long-lasting bacteremia in reservoir-adapted (natural host or passive carrier of a microorganism) and opportunistic hosts. with the advent of more sensitive and specific diagnostic tests, there is evolving microbiological evidence supporting concurrent infection with one or more bartonella spp. in more than one family member; however, the mode(s) of transmission to or among family members remains unclear. ... | 2015 | 25740763 |
| full-thickness macular hole in bartonella henselae neuroretinitis in an 11-year-old girl. | cat scratch disease is a febrile illness caused by bartonella henselae and is associated with rash at the site of cat bite or scratch and regional lymphadenopathy. various ocular manifestations of cat scratch disease have been described, mainly retinochoroiditis, optic disc swelling, neuroretinitis, vascular occlusive events, serous retinal detachment, vitreous hemorrhage, intermediate uveitis, inflammatory lesions of the optic nerve head and rarely full thickness macular hole. we describe a cas ... | 2017 | 25709274 |
| [disseminated infection due to bartonella henselae in a kidney transplant recipient]. | | 2015 | 25665525 |
| atypical presentation of cat-scratch disease in an immunocompetent child with serological and pathological evidence. | typical cat-scratch disease (csd) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. an atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. systemic csd may mimic more serious disorders like malignancy or tuberculosis. although a diagnosis is difficult to establish in systemic csd, an early diagnosis and an appropriate treatment are important to prevent complications. bartonella henselae is di ... | 2014 | 25610689 |
| vector-borne pathogens in arctic foxes, vulpes lagopus, from canada. | because of the relatively low biodiversity within arctic ecosystems, arctic foxes, vulpes lagopus, could serve as sentinels for the study of changes in the ecology of vector-borne zoonotic pathogens. the objective of this study was to determine the molecular prevalence of 5 different genera of vector borne pathogens (anaplasma, babesia, bartonella, ehrlichia, and hemotropic mycoplasma spp.) using blood collected from 28 live-trapped arctic foxes from the region of karrak lake, nunavut, canada. b ... | 2015 | 25596149 |
| neuroretinitis secondary to bartonella henselae in the emergent setting. | | 2017 | 25586979 |
| the efficacy of a selamectin (stronghold ®) spot on treatment in the prevention of bartonella henselae transmission by ctenocephalides felis in cats, using a new high-challenge model. | bartonella henselae is the causative agent of cat scratch disease in humans, which is recognized as an emerging zoonotic disease. ctenocephalides felis is the main vector, and transmission of b. henselae infection between cats and humans occurs mainly through infected flea feces. control of feline infestation with this arthropod vector therefore provides an important strategy for the prevention of infection of both humans and cats. in the present study, a new challenge model is used to evaluate ... | 2015 | 25582566 |
| a 31-year-old man with bilateral blurry vision and floaters. | we report a case of bilateral multifocal retinochoroiditis and bilateral optic disc edema in a patient with cat-scratch disease from bartonella henselae. the patient initially had negative serologic testing. repeat testing showed a markedly increased igg and igm convalescent titer and the development of a branch retinal artery and vein occlusion. in patients for whom there is a high clinical suspicion of cat-scratch disease, a convalescent titer should be obtained 2-3 weeks following a negative ... | 2015 | 27330461 |
| rickettsial diseases and ectoparasites from military bases in japan. | ectoparasitic arthropods are often vectors of rickettsiosis. we conducted a survey of ectoparasites on u.s. military facilities throughout japan with the use of specimens submitted by pest control, public health, and veterinary personnel. over 1,600 individual ectoparasites were collected. fifteen species were identified, including several significant vectors of human diseases such as scrub typhus and rickettsial spotted fevers. these ectoparasites included ctenocephalides felis , haemaphysalis ... | 2015 | 25548900 |
| neuroretinitis secondary to bartonella henselae in the emergent setting. | | 2015 | 25497596 |
| possible infectious causes of spontaneous splenic rupture: a case report. | spontaneous atraumatic splenic rupture is a rare but dramatic occurrence that is most commonly attributed to infection or neoplasia. deciphering the etiology can be challenging with many cases remaining unclear despite full investigation. | 2014 | 25433804 |
| the etiology of juvenile idiopathic arthritis. | over the years, the commonly used term to describe juvenile idiopathic arthritis (jia) has changed. by definition, jia includes all types of arthritis with no apparent cause, lasting more than 6 weeks, in patients aged less than 16 years at onset. jia pathogenesis is still poorly understood: the interaction between environmental factors and multiple genes has been proposed as the most relevant working mechanism to the development of jia. the concept that various microbes that colonize or infect ... | 2015 | 25384710 |
| cat scratch disease, a rare cause of hypodense liver lesions, lymphadenopathy and a protruding duodenal lesion, caused by bartonella henselae. | a 46-year-old woman presented with right upper abdominal pain and fever. at imaging, enlarged peripancreatic and hilar lymph nodes, as well as hypodense liver lesions, were detected, suggestive of malignant disease. at endoscopy, the mass adjacent to the duodenum was seen as a protruding lesion through the duodenal wall. a biopsy of this lesion, taken through the duodenal wall, showed a histiocytic granulomatous inflammation with necrosis. serology for bartonella henselae igm was highly elevated ... | 2014 | 25355744 |
| bartonella henselae infections in an owner and two papillon dogs exposed to tropical rat mites (ornithonyssus bacoti). | after raccoons were trapped and removed from under a house in new york, the owner and her two papillon dogs became infested with numerous rat mites (ornithonyssus bacoti). two weeks later, both dogs developed pruritus, progressively severe vesicular lesions, focal areas of skin exfoliation, swelling of the vulva or prepuce, abdominal pain, and behavioral changes. two months after the mite infestation, the owner was hospitalized because of lethargy, fatigue, uncontrollable panic attacks, depressi ... | 2014 | 25325313 |
| cat scratch disease in kidney transplant receptors: is it a rare or underdiagnosed pathology? | cat scratch disease (csd) is an infectious disorder which appears after cat scratching particularly in children and adolescents. bartonella henselae is the etiologic agent more frequently involved. there are only a few recent reports demonstrating the disease after transplantation, although the illness is not infrequent in immunologically competent people. indeed csd in transplant receptors has only been recently emphasized in the literature and it was concluded that fever and lymphadenopathy in ... | 2016 | 25317626 |
| evaluation of indirect immunofluorescence antibody test and enzyme-linked immunosorbent assay for the diagnosis of infection by leishmania infantum in clinically normal and sick cats. | cats that live in areas where canine and human leishmaniosis due to leishmania infantum is endemic may become infected and may develop anti-leishmania antibodies. in this study 50 clinically normal and 50 cats with cutaneous and/or systemic signs that lived in an endemic area and had been previously examined for infection by l. infantum using pcr in four different tissues were serologically tested for the presence of anti-leishmania igg (ifat and elisa) and igm (ifat). the aim was to compare the ... | 2014 | 25307685 |
| [cat scratch disease as a differential diagnosis in a patient with swelling in the groin]. | at scratch disease is caused by the bacteria bartonella henselae and presents in patients exposed to a scratch/bite from cats. we present a case with a 12-year-old boy with an enlarged inguinal lymph node, initially suspected to be a femoral hernia by ultrasonography. histologic examination of an inguinal lymph node showed necrosis and b. henselae infection. it is important with a thorough anamnesis including any history of animal bites/scratch and it should be kept in mind as a differential dia ... | 2014 | 25293409 |
| concurrent bartonella henselae infection in a dog with panniculitis and owner with ulcerated nodular skin lesions. | bartonella henselae, a gram-negative, zoonotic alphaproteobacteria that infects erythrocytes, endothelial cells and dendritic cells, has previously been implicated as a cause of panniculitis in dogs and a human. | 2015 | 25292107 |
| exposure and risk factors to coxiella burnetii, spotted fever group and typhus group rickettsiae, and bartonella henselae among volunteer blood donors in namibia. | the role of pathogen-mediated febrile illness in sub-saharan africa is receiving more attention, especially in southern africa where four countries (including namibia) are actively working to eliminate malaria. with a high concentration of livestock and high rates of companion animal ownership, the influence of zoonotic bacterial diseases as causes of febrile illness in namibia remains unknown. | 2014 | 25259959 |
| [bartonella henselae infection-cat-scratch disease in children (case report)]. | this study was designed to investigate the 11 year old patient with cat scratch disease. the diagnoes of this infection was based on detailed history, physical examenination and para-clinical data analyses. in case of cat-scratch disease (because it is rare diagnosis), a different approach is required to every specific occaison. a series of investigations (most informative is intrinsic factor antibody - ifa) should be conducted to determain the cat-scratch disease from the various reasons of the ... | 2014 | 25214279 |
| causative agents of kikuchi-fujimoto disease (histiocytic necrotizing lymphadenitis): a meta-analysis. | kikuchi-fujimoto disease (kfd) is a self-limiting disorder characterized by histiocytic necrotizing lymphadenitis in the cervical lymph nodes of young women. although an infectious etiology has been postulated, a definitive causative agent has not been identified. the few dozens of published studies are limited by small sample size and poorly structured study designs. the purpose of this study is to evaluate the association of each infectious agent to kfd that has been studied. | 2014 | 25200851 |
| cat scratch disease. | approximately 24,000 people are infected with cat scratch disease (csd) every year. csd is caused by the bacteria bartonella henselae, a gram-negative bacteria most often transmitted to humans through a bite or scratch from an infected cat or kitten. although csd is often a benign and self-limiting condition, it can affect any major organ system in the body, manifesting in different ways and sometimes leading to lifelong sequelae. it is a disease that is often overlooked in primary care because ... | 2014 | 25199244 |
| [bartonella henselae in children with regional adenitis treated in a peruvian national hospital, 2012]. | in order to determine the frequency of seropositive cases of bartonella henselae in children with regional adenitis treated in a national hospital in peru, a cross-sectional study was conducted in 106 children with regional adenitis greater than 1 cm in diameter. the sample was selected from patients aged 5-11 years seen at the national institute of child health for acute onset of regional adentitis, with more than five days of symptoms. b. henselae seropositivity was defined by indirect immunof ... | 2014 | 25123865 |
| neuroretinitis in ocular bartonellosis: a case series. | we report a case series of neuroretinitis in ocular bartonellosis and describe the serologic verification for bartonella henselae. this is a retrospective interventional case series of four patients who presented in the ophthalmology clinic of hospital universiti sains malaysia from june 2012 to march 2013. all four patients had a history of contact with cats and had fever prior to ocular symptoms. each patient presented with neuroretinitis characterized by optic disc swelling with macular star. ... | 2014 | 25120352 |
| molecular identification of bartonella henselae in a seronegative cat scratch disease patient with aids in rio de janeiro, brazil. | bartonella henselae is associated with a wide spectrum of clinical manifestations, including cat scratch disease, endocarditis and meningoencephalitis, in immunocompetent and immunocompromised patients. we report the first molecularly confirmed case of b. henselae infection in an aids patient in state of rio de janeiro, brazil. although dna sequence of b. henselae has been detected by polymerase chain reaction in a lymph node biopsy, acute and convalescent sera were nonreactive. | 2015 | 25076441 |
| diagnosis of bartonella henselae prosthetic valve endocarditis in man, france. | | 2014 | 25061808 |
| [seroprevalence of bartonella henselae and bartonella quintana in blood donors in aydin province, turkey]. | bartonella species cause several diseases in humans such as cat stratch disease, bacillary angiomatosis, peliosis hepatis, endocarditis, carrion disease and trench fever. cat scratch disease and bacillary angiomatosis cases have already been reported in turkey. studies from our region, namely aydin (a province located at western anatolia, turkey) indicated that mean bartonella henselae igg seropositivity rate is 11.5% in risk groups and may reach to 26.5% in pet owners. the aim of this study was ... | 2014 | 25052114 |
| pradofloxacin: a novel veterinary fluoroquinolone for treatment of bacterial infections in cats. | pradofloxacin is a novel third-generation oral veterinary fluoroquinolone with activity against gram-positive aerobic bacteria and anaerobes (lower minimum inhibitory concentrations in vitro). it also has activity against other bacterial species, including bartonella henselae, pasteurella multocida, bordetella bronchiseptica, extra-intestinal escherichia coli, and some mycobacterial species. this review focuses on the current knowledge of the mechanism of action, adverse effects, clinical applic ... | 2014 | 24997792 |
| [cat scratch disease: still current zoonosis]. | a retrospective evaluation of a group of patients which is focused on clinical picture, serological diagnosis, therapy and familial occurrence of the disease. | 2014 | 24960257 |
| bartonella henselae endocarditis and glomerulonephritis with dominant c3 deposition in a 21-year-old male with a melody transcatheter pulmonary valve: case report and review of the literature. | we report a case of a 21-year-old young man with underlying congenital heart disease who developed bartonella henselae endocarditis of the right ventricular outflow tract (rvot) conduit of his melody transcatheter (percutaneous) pulmonary valve (tpv), with an initial presentation of glomerulonephritis with a dominant c3 pattern, with renal failure and circulating cryoglobulins. there are few reports of a glomerulonephritis with a dominant c3 pattern presenting as a manifestation of b. henselae e ... | 2015 | 24896298 |
| single hypovascular focal splenic lesion from bartonella henselae infection. | | 2014 | 24883140 |
| murine typhus associated with parinaud's oculoglandular syndrome in 2 children. | an 11-year-old-girl and a 13-year-old-boy presented with characteristic findings of parinaud's oculoglandular syndrome. the girl was initially suspected of having bartonella henselae infection and the boy was initially diagnosed as francisella tularensis infection. both children had laboratory-confirmed infection with rickettsia typhi. | 2014 | 24853542 |
| development of an enzyme-linked immunosorbent assay for bartonella henselae infection detection. | several serological diagnostics rely on enzyme-linked immunosorbent assay (elisa) to detect bacterial infections. however, for some pathogens, including bartonella henselae, diagnosis still depends on manually intensive, time-consuming assays including micro-immunofluorescence, western blotting or indirect immunofluorescence. for such pathogens, there is obviously still a need to identify antigens to establish a reliable, fast and high-throughput assay (dupon et al. ). we evaluated two b. hensel ... | 2014 | 24834970 |
| bartonella henselae infection inducing hemophagocytic lymphohistiocytosis in a kidney transplant recipient. | bartonella henselae (bh) is the cause of cat-scratch fever. when infection is symptomatic, it typically presents with singular lymphadenitis and fever. less commonly, the infection can become disseminated and cause endocarditis, osteomyelitis, and micro-abscesses in multiple sites including liver, spleen, eyes, and brain, especially in immunocompromised patients. hemophagocytic lymphohistiocytosis (hlh) is a rare and severe multisystem disorder that may be triggered by infections. in one prior c ... | 2014 | 24829973 |
| fever and lymphadenitis in an immunocompromised patient. | bartonella henselae infections are among the most common causes of fever and lymphadenopathies, but can lead to severe complications in immunocompromised hosts; early recognition of these infections is of paramount importance in immunocompromised patients. | 2014 | 24820922 |
| identification of bartonella henselae in the liver of a thoroughbred foal with severe suppurative cholangiohepatitis. | | 2017 | 24814868 |
| multifocal chorioretinitis caused by bartonella henselae: imaging findings of spectral domain optical coherence tomography during treatment with trimethoprim-sulfamethoxazole. | | 2014 | 24763244 |
| [fever of unknown origin: a challenge for the pediatric infectious diseases specialist]. | prolonged febrile syndrome (pfs) is defined as fever 7-10 days, with initial study does not allow etiologic diagnosis. | 2014 | 24740780 |
| a case report of seronegative cat scratch disease, emphasizing the histopathologic point of view. | cat scratch disease, necrotizing granulomatous lymphadenitis caused by bartonella henselae, usually benign and self-limited. however, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. we report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. he had a history of cat bite on the left hand dorsum. on excision, the lymph node showed follicular hyperplasia, stellat ... | 2014 | 24641870 |
| bartonella henselae and b. koehlerae dna in birds. | | 2014 | 24589235 |
| visceral cat scratch disease with endocarditis in an immunocompetent adult: a case report and review of the literature. | infective endocarditis and hepatosplenic abscesses are rare manifestations of cat scratch disease (csd), especially among immunocompetent adults. an otherwise healthy woman who presented with fever and abdominal pain was diagnosed with multiple abscesses in the spleen and the liver, as well as a mitral valve vegetation. pcr on spleen tissue was positive for bartonella henselae. prolonged treatment with doxycycline and gentamicin led to complete recovery. review of the literature revealed 18 case ... | 2014 | 24575798 |
| proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism. | proteomics data provide unique insights into biological systems, including the predominant subcellular localization (scl) of proteins, which can reveal important clues about their functions. here we analyzed data of a complete prokaryotic proteome expressed under two conditions mimicking interaction of the emerging pathogen bartonella henselae with its mammalian host. normalized spectral count data from cytoplasmic, total membrane, inner and outer membrane fractions allowed us to identify the pr ... | 2014 | 24486812 |
| first case of bartonella henselae bacteremia in korea. | bartonella henselae causes cat-scratch disease, bacteremia, and various focal infections. despite the worldwide occurrence of b. henselae infections, reports in humans are rare in korea. the clinical manifestation of all 5 previously reported cases was lymphadenopathy. herein, we report a case of bacteremia in a woman who presented with prolonged fever. b. henselae was isolated from a blood specimen by cell culture. conventional polymerase chain reaction amplification and sequencing of the 16s-2 ... | 2013 | 24475360 |
| molecular detection of rickettsia felis and bartonella henselae in dog and cat fleas in central oromia, ethiopia. | fleas are important vectors of several rickettsia and bartonella spp. that cause emerging zoonotic diseases worldwide. in this study, 303 fleas collected from domestic dogs and cats in ethiopia and identified morphologically as ctenocephalides felis felis, c. canis, pulex irritans, and echidnophaga gallinacea were tested for rickettsia and bartonella dna by using molecular methods. rickettsia felis was detected in 21% of fleas, primarily c. felis, with a similar prevalence in fleas from dogs and ... | 2014 | 24445204 |
| cat-scratch disease in adult hospitalized for prolonged-fever associated with multiple lymphadenopathies and weight loss. | we report a 19-year-old patient with a cat-scratch disease presenting three months continuous alteration of the general condition, including prolonged-fever, anorexia, asthenia, weight loss associated with adenitis and multiple thoracic-abdominal adenopathies, leukocytosis with neutrophil polynuclear predominance, and increased of c-reactive protein. the serologies of toxoplasmosis, infectious mononucleosis, human immunodeficiency virus, brucellosis, bartonellosis and the tuberculosis research b ... | 2013 | 24403980 |
| symptomatic peripheral mycotic aneurysms due to infective endocarditis: a contemporary profile. | peripheral mycotic aneurysms (pmas) are a relatively rare but serious complication of infective endocarditis (ie). we conducted the current study to describe and compare the current epidemiologic, microbiologic, clinical, diagnostic, therapeutic, and prognostic characteristics of patients with symptomatic pmas (spmas). a descriptive, comparative, retrospective observational study was performed in 3 tertiary hospitals, which are reference centers for cardiac surgery. from 922 definite ie episodes ... | 2014 | 24378742 |
| cat-scratch disease: unusual perivascular chorioretinal lesions. | this study is a case report of bilateral perivascular chorioretinal lesions associated with bartonella henselae. a 37-year-old woman presented with headache and blurred vision in both eyes aggravating occasionally during five years. she was otherwise healthy, with best-corrected visual acuities were 20/20 in both eyes. history of close contact with cats was more than merely eye-catching upon examination of her fundus. in both eyes, fundi were coated with yellow-brown pigmented perivenous chorior ... | 2014 | 25756063 |
| vector-borne agents detected in fleas of the northern white-breasted hedgehog. | this is the first large-scale molecular investigation of fleas from a geographically widespread and highly urbanized species, the northern white-breasted hedgehog. in this study, 759 fleas (the majority were archaeopsylla erinacei) collected from 134 hedgehogs were molecularly analyzed individually or in pools for the presence of three groups of vector-borne pathogens. all flea samples were positive for rickettsiae: in two samples (1.5%) rickettsia helvetica and in 10% of the others a novel rick ... | 2014 | 24359423 |
| neuroretinitis with branch retinal artery occlusion in a 15-year-old female. | we report a case of bartonella henselae neuroretinitis with significant disc and peripapillary edema, branch retinal artery occlusion without macula involvement and well preserved central vision. a 15-year-old female presented with loss of vision over 4 weeks in the left eye. she had a history of cat exposure, but a cat scratch, insect bite or conjunctivitis was not reported. an inferotemporal arcuate scotoma developed during the acute phase and persisted over the course of the follow-up. | 2013 | 24348414 |
| analysis of seroreactivity against cell culture-derived bartonella spp. antigens in dogs. | little is known about the specificity of bartonella spp. immunofluorescent antibody (ifa) assays in dogs. bacteremia in sick dogs most often has been associated with bartonella henselae (bh), bartonella vinsonii subspecies berkhoffii (bvb), and bartonella koehlerae (bk). clarification of the diagnostic utility of ifa serology when testing against these organisms is needed. | 2017 | 24341682 |
| cat scratch disease and lymph node tuberculosis in a colon patient with cancer. | a 71-year-old man operated for a sigmoid tumour remained in the surveillance after adjuvant chemotherapy. after 3 years, a left axillary lymph node was visible on ct scan. the biopsy revealed a necrotising and abscessed granulomatous lymphadenitis, suggestive of cat scratch disease. the patient confirmed having been scratched by a cat and the serology for bartonella henselae was igm+/igg-. direct and culture examinations for tuberculosis were negative. the patient was treated for cat scratch dis ... | 2013 | 24334464 |
| experimental infection of dogs with various bartonella species or subspecies isolated from their natural reservoir. | dogs can be infected by a wide variety of bartonella species. however, limited data is available on experimental infection of dogs with bartonella strains isolated from domestic animals or wildlife. we report the inoculation of six dogs with bartonella henselae (feline strain 94022, 16s rrna type ii) in three sets of two dogs, each receiving a different inoculum dose), four dogs inoculated with b. vinsonii subsp. berkhoffii type i (atcc strain, one mongrel dog) or type ii (coyote strain, two bea ... | 2014 | 24315039 |
| comparative microbiological features of bartonella henselae infection in a dog with fever of unknown origin and granulomatous lymphadenitis. | we report the first documented case of bartonella henselae infection in a dog from france and the first isolation of b. henselae from a dog with fever of unknown origin. this observation contributes to the "one health" concept focusing on zoonotic pathogens emerging from companion animals. a 1-year-old female german shepherd dog was referred for evaluation of fever of unknown origin of 1 month duration. diagnostic investigations confirmed diffuse pyogranulomatous lymphadenitis. the dog became af ... | 2014 | 24310419 |
| [cat scratch disease as fever of unknown origin]. | the cat scratch disease is a relatively rare disease caused by bartonella henselae. only a small proportion of the cases that described extranodal involvement occurs. we report a 11 year old male patient with persistent fever, liver and osteoarticular involvement with a predominance of dorsolumbar spine. evolution was satisfactory with complete clinical and imaging evidenced recovery in several months of monitoring. case was analyzed considering eag published literature, emphasizing the need to ... | 2013 | 24248115 |
| bartonella spp. in cats from buenos aires, argentina. | in argentina, data on the presence of members of the genus bartonella is scarce. to increase knowledge about these zoonotic pathogens in this country, the presence and variability of bartonella spp. was investigated in cats and dogs from buenos aires. bartonella spp. was detected in 17.8% of cats, while all dogs tested negative by pcr and reverse line blot. b. henselae was the most frequent species, being detected in 11.9% (14/101), while b. clarridgeiae was found in only 5.9% (6/101) of the cat ... | 2014 | 24247021 |
| bone scintigraphy in children with cat scratch disease. | the objective of this study was to evaluate the degree and incidence of bone involvement in patients with cat scratch disease. | 2013 | 24152635 |
| managing iron supply during the infection cycle of a flea borne pathogen, bartonella henselae. | bartonella are hemotropic bacteria responsible for emerging zoonoses. most bartonella species appear to share a natural cycle that involves an arthropod transmission, followed by exploitation of a mammalian host in which they cause long-lasting intra-erythrocytic bacteremia. persistence in erythrocytes is considered an adaptation to transmission by bloodsucking arthropod vectors and a strategy to obtain heme required for bartonella growth. bartonella genomes do not encode for siderophore biosynt ... | 2013 | 24151576 |
| detection of serum antibodies against bartonella species in cats with sporotrichosis from rio de janeiro, brazil. | cat scratch disease is a zoonosis caused by bartonella species, transmitted to humans through scratches or bites from infected cats and via direct contact with infected feces. sporotrichosis, caused by the fungal complex sporothrix, is transmitted by traumatic inoculation of the fungus. cats are important in zoonotic transmission. serum samples from 112 domestic cats with sporotrichosis and 77 samples from healthy cats were analyzed by indirect immunofluorescence assay (ifa), using the commercia ... | 2014 | 24127458 |
| experimental infection of dogs with bartonella henselae and bartonella vinsonii subsp. berkhoffii. | the lack of a suitable infection model remains an important obstacle for the pathophysiological understanding of bartonella spp. the following pilot study was designed to determine whether cell culture-grown bartonella henselae sa2 and bartonella vinsonii subsp. berkhoffii genotype iii would cause persistent bacteremia in dogs. pre-inoculation screening established that two laboratory-raised golden retrievers were naturally-infected with bartonella koehlerae. despite prior infection, one dog eac ... | 2013 | 24120155 |
| cat-scratch disease. | to discuss the systemic and ocular manifestations, diagnosis and treatment of bartonella infection. | 2014 | 24107122 |
| unilateral neuroretinitis secondary to bartonella henselae infection. | | 2014 | 24106074 |
| [an uncommon cutaneous presentation of cat scratch disease]. | herein we report a case of cat scratch disease on account of its atypical presentation. | 2013 | 24090891 |
| [preauricular lymphadenopathy related to bartonella henselae]. | cat scratch disease is characterized by adenitis with usually positive outcome. we reported two cases of cat scratch disease with preauricular involvement occurring in immunocompetent patients. | 2013 | 24080238 |
| accurate prediction of bacterial type iv secreted effectors using amino acid composition and pssm profiles. | various human pathogens secret effector proteins into hosts cells via the type iv secretion system (t4ss). these proteins play important roles in the interaction between bacteria and hosts. computational methods for t4ss effector prediction have been developed for screening experimental targets in several isolated bacterial species; however, widely applicable prediction approaches are still unavailable | 2013 | 24064423 |
| dual input control: activation of the bartonella henselae virb/d4 type iv secretion system by the stringent sigma factor rpoh1 and the batr/bats two-component system. | the co-ordinated expression of virulence factors is a critical process for any bacterial pathogen to colonize its host. here we investigated the mechanisms of niche adaptation of the zoonotic pathogen bartonella henselae by combining genetic approaches and shotgun proteomics. we demonstrated that expression of the virb/d4 type iv secretion system (t4ss) and its secreted effector proteins require the alternative sigma factor rpoh1, which levels are controlled by the stringent response (sr) compon ... | 2013 | 24033511 |
| retinal arterial occlusive disease in a young patient with cat scratch disease. | to report an unusual case of a branch retinal arterial occlusion and bilateral multifocal retinitis in a young woman with cat scratch disease. | 2013 | 24019792 |
| co-existence of acute transverse myelitis and guillain-barré syndrome associated with bartonella henselae infection. | cat scratch disease (csd) is a benign, self-limiting condition associated with bartonella henselae. neurological manifestations are uncommon. acute transverse myelitis and guillain-barré syndrome have been reported rarely with csd. this report describes a 12-year-old boy with acute transverse myelitis and guillain-barré syndrome associated with csd. | 2013 | 23930734 |
| serpiginous choroiditis secondary to bartonella henselae? | | 2013 | 23929519 |
| directed shotgun proteomics guided by saturated rna-seq identifies a complete expressed prokaryotic proteome. | prokaryotes, due to their moderate complexity, are particularly amenable to the comprehensive identification of the protein repertoire expressed under different conditions. we applied a generic strategy to identify a complete expressed prokaryotic proteome, which is based on the analysis of rna and proteins extracted from matched samples. saturated transcriptome profiling by rna-seq provided an endpoint estimate of the protein-coding genes expressed under two conditions which mimic the interacti ... | 2013 | 23878158 |
| [bilateral neuroretinitis as an ocular manifestation of cat scratch disease in 9-year-old boy. a case report]. | 1. to highlight a less-known clinical entity neuroretinitis and the need for differentiation of this entity from the other retinal disease that can mimic. 2. to be familiar with ocular finding in cat scratch disease. | 2013 | 23822598 |
| bartonella species infection in cats: abcd guidelines on prevention and management. | over 22 bartonella species have been described in mammals, and bartonella henselae is most common worldwide. cats are the main reservoir for this bacterium. b henselae is the causative agent of cat scratch disease in man, a self-limiting regional lymphadenopathy, but also of other potentially fatal disorders in immunocompromised people. | 2013 | 23813816 |
| the bartonella henselae sitabcd transporter is required for confronting oxidative stress during cell and flea invasion. | bartonella henselae is a zoonotic pathogen that possesses a flea-cat-flea transmission cycle and causes cat scratch disease in humans via cat scratches and bites. in order to establish infection, b. henselae must overcome oxidative stress damage produced by the mammalian host and arthropod vector. b. henselae encodes for putative fe²⁺ and mn²⁺ transporter sitabcd. in b. henselae, sitab knockdown increases sensitivity to hydrogen peroxide. we consistently show that sitab knockdown decreases the a ... | 2013 | 23811032 |
| [headaches, fever and dysuria in a 39-year-old man]. | | 2013 | 23790720 |
| cat-scratch disease presenting as a solitary splenic abscess in an immunocompetent adult: case report and literature review. | cat-scratch disease is a common zoonotic infectious disease caused by bartonella henselae. it is generally characterized by regional lymphadenopathy following exposure to an infected cat. organ systemic manifestations occur rarely in atypical forms of the disease. abscess of the spleen represents a rare, life-threatening clinical entity. here we report an unusual case of cat scratch disease presenting as an isolated splenic abscess in an immunocompetent adult. comprehensive social history reveal ... | 2013 | 23774977 |
| macular hole: a rare complication of ocular bartonellosis. | a 37-year-old woman presented with an anterior optic neuropathy related to bartonella henselae. twenty-nine days after symptom onset, a partial thickness macular hole developed in the involved eye. fundus photography and optical coherence tomography confirmed the conversion to a full-thickness macular hole in 2 months. macular hole as a complication of cat scratch disease is a rare entity, with 2 prior reported cases in children. the development of a macular hole following cat scratch disease ca ... | 2013 | 23681239 |
| [accuracy and diagnostic utility of igm in bartonella henselae infections]. | laboratory diagnosis of cat scratch disease (csd) is based on the determination of specific antibodies anti-bartonella henselae by different techniques. the cdc recommends igg by immunofluorescent assay (ifa) as the gold standard. | 2013 | 23677149 |
| [osteomyelitis in cat scratch disease: a case report and literature review]. | cat scratch disease is the most common zoonosis in humans and its typical expression is a persistent benign regional adenopathy. in some rare cases, mono- or multifocal osteomyelitis is described. in this paper, we report the case of bone lesions in a 13-year-old girl infected with cat scratch disease. we have also undertaken a literature review and analyzed 60 other such cases. the manifestation of a bone lesion associated with cat scratch disease was characterized by a mono- or multifocal infe ... | 2013 | 23628125 |
| challenges in the diagnosis of culture negative vertebral osteomyelitis in adults: case of bartonella henselae infection. | | 2013 | 23618804 |
| [neuroretinitis caused by bartonella henselae: a case with follow up through optical coherence tomography]. | the case of a 36 year-old male with neuroretinitis caused by bartonella henselae is reported, whose periodic follow-up was done through optical coherence tomography (oct). the onset of this disease was characterized by unilateral low visual acuity (va), painless, of sudden onset, in the right eye (re), associated to l febrile symptom. the funduscopic examination showed edema in the posterior pole which extended from the optical disc to the macular region in the re. the oct confirmed macular and ... | 2013 | 23612827 |
| bartonella henselae bacteremia in a mother and son potentially associated with tick exposure. | bartonella henselae is a zoonotic, alpha proteobacterium, historically associated with cat scratch disease (csd), but more recently associated with persistent bacteremia, fever of unknown origin, arthritic and neurological disorders, and bacillary angiomatosis, and peliosis hepatis in immunocompromised patients. a family from the netherlands contacted our laboratory requesting to be included in a research study (ncsu-irb#1960), designed to characterize bartonella spp. bacteremia in people with e ... | 2013 | 23587194 |
| [cat scratch disease with deradenoncus and high fever: report of one case]. | cat scratch disease (csd) is a bacterial disease caused by bartonella henselae. it is mainly characterized by self-limiting lymphadenopathy in the draining site after cat scratch or bite. this paper reported a case of cat scratch disease with deradenoncus and high fever, and discussed the etiology, pathogenesis, epidemiology, pathology, clinical characteristics, diagnosis and treatment methods of csd. | 2013 | 23552796 |
| diagnosis and follow-up of bartonella henselae infection in the spleen of an immunocompetent patient by real-time quantitative pcr. | systemic bartonella henselae infections are unusual in immunocompetent adults. however, here we report one such case of bartonellosis in a 34-year-old patient, who presented with fever and multinodular splenomegaly. we also describe a novel method of identifying bartonella henselae by real-time quantitative polymerase chain reaction and sequencing of amplified products. this could prevent splenic bartonellosis being mistaken for lymphoma and thereby avert unnecessary splenectomy. | 2013 | 23518653 |
| central scotoma without prodromal illness caused by bartonella henselae neuroretinitis. | this case report describes bartonella henselae neuroretinitis in a 26-year-old woman who presented to the emergency department with unilateral central scotoma and no prodromal symptoms, a unique presentation of this disease. b henselae, a gram-negative bacteria, is the cause of cat scratch disease. cat scratch disease (csd) is a self-limiting illness, which typically presents with regional lymphadenopathy, fever, and small skin lesions in associationwith a cat scratch or bite. the mostcommon ocu ... | 2013 | 23481153 |
| bartonella henselae infection associated with autoimmune thyroiditis in a child. | bartonella henselae was discovered a quarter of a century ago as the causative agent of cat-scratch disease. more recently, bartonella has been found to be responsible for a broad range of clinical syndromes (prolonged fever, hepatosplenic disease, encephalopathies, ocular disease) and associated with autoimmune conditions. | 2013 | 23446023 |
| small indian mongooses and masked palm civets serve as new reservoirs of bartonella henselae and potential sources of infection for humans. | the prevalence and genetic properties of bartonella species were investigated in small indian mongooses and masked palm civets in japan. bartonella henselae, the causative agent of cat-scratch disease (csd) was isolated from 15.9% (10/63) of the mongooses and 2.0% (1/50) of the masked palm civets, respectively. the bacteraemic level ranged from 3.0 × 10(1) to 8.9 × 10(3) cfu/ml in mongooses and was 7.0 × 10(3) cfu/ml in the masked palm civet. multispacer typing (mst) analysis based on nine inter ... | 2013 | 23433322 |
| bartonella henselae infection: an uncommon mimicker of autoimmune disease. | we present a case of a seven-year-old immunocompetent female patient who developed systemic symptoms mimicking an autoimmune rather than an infectious disease. the patient presented with rash, biquotidian fever, night sweats, and arthralgias. there was no antecedent history of cat contact. investigations showed increased inflammatory markers, leukocytosis, thrombocytosis, hypercalcemia, and raised angiotensin-converting enzyme. interferon-gamma releasing assay for tuberculosis infection was nega ... | 2013 | 23424700 |
| granulomatous lesions in bone marrow: clinicopathologic findings and significance in a study of 48 cases. | granulomas in bone marrow are an infrequent finding related to various disorders. the aim of this study was to review our clinical experience with granulomatous bone marrow disease and to describe the contributions of recent diagnostic tools, such as (18)f-fluorodeoxyglucose positron emission tomography ((18)f-fdg-pet) and molecular biology. | 2013 | 23414770 |
| atypical form of cat scratch disease in immunocompetent patient. | cat scratch disease (csd) is an acute infectious disease with benign course caused by the bacteria bartonella henselae. clinically, it is usually manifested as regional lymphadenopathy and mild infective syndrome. rare forms of the disease which usually occur in immunocompromised presons are: encephalitis, transverse myelitis, neuroretinitis, granulomatosus conjunctivitis, arthritis, hepatitis etc. | 2013 | 23401934 |
| depolymerization of cytokeratin intermediate filaments facilitates intracellular infection of hela cells by bartonella henselae. | bartonella henselae is capable of invading epithelial and endothelial cells by modulating the function of actin-dependent cytoskeleton proteins. although understanding of the pathogenesis has been increased by the development of an in vitro infection model involving endothelial cells, little is known about the mechanism of interaction between b. henselae and epithelial cells. this study aims to identify the binding candidates of b. henselae in epithelial cells and explores their effect on b. hen ... | 2013 | 23359593 |
| a flea and tick collar containing 10% imidacloprid and 4.5% flumethrin prevents flea transmission of bartonella henselae in cats. | bartonella henselae is transmitted amongst cats by ctenocephalides felis and is associated with multiple clinical syndromes in cats and people. in a previous study, monthly spot-on administration of 10% imidacloprid/1% moxidectin was shown to block transmission of b. henselae amongst cats experimentally exposed to infected c. felis. the purpose of this study was to determine whether application of a flea and tick collar containing 10% imidacloprid and 4.5% flumethrin would lessen c. felis transm ... | 2013 | 23351927 |
| [spasmodic left waist pain in a six years old child--cat scratch disease]. | cat scratch disease is caused by bartonella henselae, a bacterium transmitted to humans from cats through a scratch or by fleas. in 90% of cases, the clinical presentation is that of classical cat scratch disease where an adjacent lymph node is infected. atypical manifestations include prolonged fever, liver and spleen abscesses, infective endocarditis, central nervous system involvement etc. we present a 6 years old girl who suffered from l2 vertebral osteomyelitis and epidural abscess, initial ... | 2012 | 23350290 |
| detection of bartonella henselae dna in clinical samples including peripheral blood of immune competent and immune compromised patients by three nested amplifications. | bacteria of the genus bartonella are emerging pathogens detected in lymph node biopsies and aspirates probably caused by increased concentration of bacteria. twenty-three samples of 18 patients with clinical, laboratory and/or epidemiological data suggesting bartonellosis were subjected to three nested amplifications targeting a fragment of the 60-kda heat shock protein (hsp), the internal transcribed spacer 16s-23s rrna (its) and the cell division (ftsz) of bartonella henselae, in order to impr ... | 2013 | 23328718 |
| characteristics of bartonella spp. infections in poland in the years 2009-2012 identified in the laboratory of national institute of public health--national institute of hygiene. | various bartonella species, (gram-negative aerobic bacilli) are etiologic agents ofzoonotic diseases called bartonelloses, which manifest with different symptoms depending on the bacterial species, reservoir and vector. in poland and europe, the most common bacterial species of the genus bartonella is bartonella henselae. | 2013 | 24741910 |
| [investigation of bartonella henselae antibodies in serum and plasma samples of kidney transplant patients]. | solid organ transplantation is an important therapeutic choice to improve the life quality of patients with end-stage renal disease. renal transplant recipients have to take immunosuppressive therapy to prevent transplant rejection. however, this treatment increases susceptibility to infection. bartonella henselae causes systemic, disseminated and silent manifestations in healthy individuals, while the mortality rate is high in immunosuppressive patients in the case of untreated bartonellosis. t ... | 2012 | 23188571 |