| detection of avian and mammalian oncogenic rna viruses (oncornaviruses) by immunofluorescence. | | 1972 | 4332476 |
| human sarcomas contain rna related to the rna of a mouse leukemia virus. | labeled dna complementary to the rna of the rauscher leukemia virus was hybridized with rna from the polysome fraction of human sarcomas. eighteen out of 25 specimens contained rna possessing homology to the rna of the mouse leukemia virus but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. further, no normal adult or fetal tissues showed significant amounts of rna specific to mouse leukemia virus. it appears that human sarcomas contain rna sequ ... | 1972 | 4332759 |
| presence in human breast cancer of rna homologous to mouse mammary tumour virus rna. | | 1972 | 4332799 |
| detection of high-molecular-weight rna in particles from human milk. | particles from human milk contain a reverse transcriptase and a high-molecular-weight (60s to 70s) rna that serves as a template. these particles have two features diagnostic of known rna tumor viruses. | 1972 | 4332822 |
| rna-dependent dna polymerase in viruses and cells: views on the current state. | | 1972 | 4332948 |
| some structural and antigenic properties of intracisternal a particles occurring in mouse tumors (complement fixation-immunodiffusion-neuroblastoma-plasma-cell tumor). | intracisternal a-particles were isolated from three different myeloma lines in balb/c mice and from cultured neuroblastoma cells of a/j origin. all preparations contained a major structural protein with an apparent molecular weight near 70,000 as estimated by electrophoretic mobility in sodium dodecyl sulfate-containing polyacrylamide gels. solubilization of this component by sodium dodecyl sulfate was dependent on prior or concomitant treatment with sulfhydryl compounds. the size distribution o ... | 1972 | 4333040 |
| [increase and modification of the carcinogenic power of mammary tumors virus, after treatment with ethylene oxide; distribution of viral particles]. | | 1971 | 4333066 |
| [penetration by mature particles of mammary cancer virus in producing cells, in vivo]. | | 1971 | 4333132 |
| effect of transient immunosuppression on host response to neonatally introduced oncogenic virus. | | 1972 | 4333498 |
| [virus-like particles in breast tissue in breast carcinoma and chronic cystic mastopathy]. | | 1972 | 4333649 |
| antigenically distinct forms of mammary tumor virus in blood and mammary tissues of mice. | | 1971 | 4333722 |
| inhibition of pituitary-induced nodular hyperplasia in mammary glands of c3h mice fed a phenylalanine-deficient diet. | | 1971 | 4333726 |
| protein kinase associated with rna tumor viruses and other budding rna viruses. | | 1972 | 4333745 |
| [concept of the morphological evolution and mechanisms of transmission of mammary cancer virus: attempted generalization]. | | 1971 | 4333760 |
| rna in human leukemic cells related to the rna of a mouse leukemia virus (leukocytes-rna-dna hybridization-rauscher virus-polysomal rna). | molecular hybridization with radioactively labeled dna complementary to the rna of the rauscher leukemia virus was used to probe for homologous rna in the polysome fraction of human leukemic cells. the leukocytes of 24 out of 27 patients examined contained rna possessing homology to that of the mouse leukemia agent, but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. further, no control human leukocytes or other adult and fetal tissues showed si ... | 1972 | 4333985 |
| evidence for translation of viral-specific rna in cells of a mouse mammary carcinoma. | a procedure is described permitting the detection of viral-specific rna in a mouse mammary tumor. the method involves molecular hybridization with radioactively labeled dna complementary to the rna of the mouse mammary-tumor virus. rna homologous to that of the mammary agent has been found in both the nuclear and polyribosomal fractions of tumor cells. the results imply that the oncogenic information is serving as messenger rna that directs the synthesis of proteins required for virus production ... | 1972 | 4335063 |
| [the viral problem in mammary tumors]. | | 1972 | 4335126 |
| relationship between organization of mammary tumors and the ability of tumor cells to replicate mammary tumor virus and to recognize growth-inhibitory contact signals in vitro. | mammary tumor virus (mtv) replication was confined primarily to cells organized as acini in intact mouse mammary glands. primary mammary tumors maintained a high degree of acinar organization and cells therein continued to replicate mtv vegetatively. nonacinar mammary cells, derived by serial transplantation of acinar tumor cells, no longer actively replicated mtv. this suggests that phenotypic differences exist among mammary epithelial cells in their ability to support virus replication, that a ... | 1972 | 4335525 |
| [comparative studies on mammary tumor virus detection in murine mammae cancer of strain cba-bln]. | | 1971 | 4335534 |
| [tumorgenesis by type b particles (mammary tumor virus) in the mouse and implications for human pathology]. | | 1971 | 4335903 |
| isolation and partial characterization of intracytoplasmic a particles. | | 1972 | 4335936 |
| spontaneous mammary tumours in spf c3h-a vy mice: formation of virus structures. | | 1972 | 4336249 |
| morphologic and functional characteristics of long-term cultures of murine myeloma cells. | murine myeloma cells proliferate well in cell culture even after up to 5 years in vitro and the globulin synthesized, as well as the ultrastructure, continues to be comparable to that of original tumor cells. globulin synthesis by cultured cells from the c3h mouse tumor (x5563) ranged from 6 to 12.2 mg/g/48 hr and by cultured cells from balb/c mouse plasmacytomas mopc 21, 31c and 315 up to 40 mg/g/48 hr. this production is greater and occurs over a more prolonged period than those reported in ot ... | 1972 | 4336548 |
| mechanisms of resistance to mammary tumor development in c57bl and i strains of mice. i. noduligenesis, tumorigenesis, and characteristics of nodules and tumors. | | 1972 | 4336864 |
| symposium on mammary neoplasia. introductory remarks. | | 1972 | 4336865 |
| considerations for epidemiologic studies to test the hypothesis of viral causation of human breast cancer. | | 1972 | 4336867 |
| possible etiological role of virus particles detected in rat and monkey mammary tumors. | | 1972 | 4336869 |
| transformation of rat mammary cell cultures by r-35 virus isolated from spontaneous rat mammary adenocarcinoma. | | 1972 | 4336870 |
| cell-associated mammary tumor virus in blood of balb-cfc3h mice. | | 1972 | 4336871 |
| interactions between viral and genetic factors in the origin of mammary tumors in mice. | | 1972 | 4336872 |
| further analysis of the detailed structure of type b and c particles. | | 1972 | 4336873 |
| pitfalls in the isolation of a human breast carcinoma virus in tissue culture. | | 1972 | 4336874 |
| immunologic aspects of tumor induction by mammary tumor virus. | | 1972 | 4336876 |
| immunization studies with mammary tumor virus. | | 1972 | 4336877 |
| immunological studies on human breast carcinoma and mouse mammary tumors. | | 1972 | 4336878 |
| effect of exogenous interferon treatment on mouse mammary tumors. | | 1972 | 4336879 |
| serologic and structural studies of mouse mammary tumor virus. | | 1972 | 4336880 |
| antigens of murine mammary tumor virus: applications to human breast cancer. | | 1972 | 4336881 |
| rna-directed dna polymerase systems: not necessarily transforming rous viruses. | | 1972 | 4336882 |
| polymerase and rna studies on milk virions from women of the parsi community. | | 1972 | 4336884 |
| virus-related rna in human and mouse mammary tumors. | | 1972 | 4336885 |
| symposium on mammary neoplasia. epilogue: quo vadis? | | 1972 | 4336886 |
| maternal modification of self-recognition in ova-transfer substrains of c3h mice. | | 1972 | 4336887 |
| [oncogenic activity of dna preparations isolated from mouse tumors and organs]. | | 1972 | 4337598 |
| serial transplantation of urethan-treated mammary nodule outgrowth line d1. | | 1972 | 4337908 |
| an antigen in human breast cancer sera related to the murine mammary tumour virus. | | 1972 | 4338143 |
| mammary noduligenic activity of the sperm from various high mammary tumor strain mice in histocompatible recipients of different ages. | | 1971 | 4338569 |
| strain differences in thymus weight in mice with different predispositions to spontaneous mammary cancer. | | 1972 | 4339293 |
| [radioresistance of the murine mammary tumor virus subjected to gamma irradiation]. | | 1972 | 4339979 |
| viral-related rna in hodgkins' disease and other human lymphomas. | molecular hybridization with radioactively labeled dna complementary to the rna of the rauscher leukemia virus was used to probe for homologous rna in human lymphomas. 22 of 32 specimens contained rna possessing homology to the rna of the mouse leukemia virus, but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. normal adult and fetal tissues failed to show significant levels of the leukemia-specific rna. it appears that human lymphomas contain r ... | 1972 | 4340156 |
| immunosuppression and cancer. | | 1972 | 4340542 |
| [immunology of mammary tumors]. | | 1972 | 4340547 |
| mammary tumour virus specific nucleotide sequences in mouse dna. | | 1972 | 4340575 |
| detection of rna-instructed dna polymerase and high molecular weight rna in malignant tissue. | an experimental procedure is detailed that permits the detection of 70s rna-directed dna synthesis in mouse mammary carcinomas. the dna synthesized is complementary to the rna of the mouse mammary tumor virus by molecular hybridization, thus, completing the proof that an rna-instructed dna polymerase has been identified. further, rna-instructed dna polymerase and its 70s rna template are physically associated in a particle that has a density characteristic of oncornaviruses. these experiments no ... | 1972 | 4340747 |
| ultrastructural cytochemistry of enzymes associated with mouse mammary tumour virus (mtv). | | 1972 | 4340767 |
| [is mammary cancer in mice a model for breast cancer in women?]. | | 1972 | 4341060 |
| influence of dietary phenylalanine deficiency on the mammary tumor virus activity in c3h mice. | | 1972 | 4343007 |
| [different effects of early thymectomy on the development of transplanted mammary neoplasms in relation to the presence of the milk factor in the recipients]. | | 1972 | 4343378 |
| [epidemiology of breast cancer]. | | 1972 | 4344435 |
| [virus-induced breast neoplasms in man?]. | | 1972 | 4345052 |
| some physical and biological characteristics of the mouse mammary tumor virus. | | 1973 | 4345152 |
| urethan and x-ray effects on mice of a tumor-resistant strain, x-gf. | | 1972 | 4345404 |
| electron microscopic study of neoplasms induced by urethan and x-rays in x-gf mice. | | 1972 | 4345405 |
| mammary gland tumors in substrains c57bl-m and c57bl-he mice. | | 1972 | 4345968 |
| structural characteristics of some murine rna tumor viruses studied by lactoperoxidase iodination. | iodination by the noninvasive enzymatic lactoperoxidase technique has been used to study the enzyme-accessible and enzyme-inaccessible proteins of three oncorna viruses (radiation leukemia virus, moloney leukemia virus, and mouse mammary tumor virus). the number and relative molecular weight of proteins associated with virion preparations purified on sucrose gradients were characterized by scans of coomassie blue-stained bands after dodecyl sulfate-polyacrylamide gel electrophoresis. gel scans f ... | 1973 | 4346036 |
| rna related to that of a murine leukemia virus in burkitt's tumors and nasopharyngeal carcinomas. | rna homologous to that of the rauscher leukemia virus has been detected in burkitt's lymphomas and nasopharyngeal carcinomas. earlier excellent experimental evidence has linked these two human tumors with the epstein-barr virus, a dna-containing agent. | 1973 | 4346039 |
| tissue culture studies of mouse mammary tumor cells and associated viruses. | | 1972 | 4346536 |
| [immunological cross reaction between human breast cancer and mammopathy and virus-producing breast carcinomas of the mouse]. | | 1972 | 4346686 |
| spontaneous immunity to mammary-tumour virus (mtv)-associated antigens in mice and its influence on syngeneic mammary-tumour growth. | | 1972 | 4346866 |
| [immunologic cross reactions between virus producing and non-virus producing murine mammary carcinoma]. | | 1972 | 4347235 |
| [ideas concerning cancer]. | | 1973 | 4347602 |
| intracytoplasmic a particles: mouse mammary tumor virus nucleoprotein cores? | a rapid method for the isolation of intracytoplasmic a particles, the putative intracellular nucleoprotein cores of mouse mammary tumor virus (mtv), is presented. spontaneous c3h/he mouse mammary tumors and transplantable mouse leydig cell tumor were used as source material. large aggregations of intracytoplasmic a particles were separated from cellular contaminants on discontinuous sucrose gradients and subsequently further purified by isopycnic banding in linear sucrose gradients. the purified ... | 1973 | 4349496 |
| dna polymerase activity and dna synthesis in preneoplastic nodule outgrowths of balb-c and c3h mouse mammary gland. | | 1973 | 4349763 |
| the biology of the mouse mammary tumor virus. | | 1972 | 4349859 |
| alteration of immunocompetence by mammary tumor virus. | | 1973 | 4350023 |
| mammary tumor virus (mtv) infection of cba/bln mice involving production of antibodies to mtv. | | 1973 | 4350662 |
| a radioimmunoassay for mtv-antigens. | | 1973 | 4352171 |
| viropexis of type b particles in reticulum cell sarcoma of r3-dm strain mice. | | 1973 | 4352364 |
| purification of virus glycoproteins by affinity chromatography using lens culinaris phytohaemagglutinin. | | 1973 | 4352507 |
| possible viral aetiology of human breast cancer. | | 1973 | 4353391 |
| improved hemagglutination inhibition assay for mammary tumor virus antigen. | it is our experience that the use of sheep red blood cells pretreated with formaldehyde and pyruvaldehyde before sensitizing with viral antigen yields results that are comparable to that obtained by using the tannic acid method. the double aldehyde method provides the added advantage of being useful for assaying the viral antigen content in substances which contain high levels of interfering substances which would preclude the use of other assay methods. | 1973 | 4353693 |
| murine mammary tumor cell clones with varying degrees of virus expression. | | 1973 | 4353952 |
| etiology of breast cancer. ii. epidemiologic aspects. | the epidemiology of breast cancer is reviewed with particular emphasis on its etiology. a number of studies suggest that differences in breast cancer incidence are associated with differences in marital status, number of pregnancies, age at menarche, age at menopause, height and weight, socioeconomic status, geographic location and residence. however, in no case is the evidence adequate to establish a "cause and effect" relationship. the genetic component of these associations may be of primary ... | 1973 | 4353980 |
| [cross reaction between human breast cancer, mastopathy and murine mamma carcinoma: localization of the antigen in type-a-particle-virus]. | | 1973 | 4354922 |
| [electronmicroscopic observations on mouse mammary tumor virus (mtv) with special regard to the extrusion of a-particles]. | | 1973 | 4355001 |
| the effect of ph on the morphology, electrophoretic mobility, and infectivity of the mouse mammary tumor virus. | | 1973 | 4355022 |
| [the effect of norsteroid treatment on the histologic structure of mastopathic breast tissue (author's transl)]. | | 1973 | 4355777 |
| envelope of mouse mammary tumor virus studied by freeze-etching and freeze-fracture techniques. | as part of a study of the cell surface changes associated with the production of murine mammary tumor virus, the structure of the envelope of this virus has been examined by using freeze-fracture techniques. both fracture and deep-etch surfaces were examined. the fracture faces contain 10-nm spheres comparable to those observed on fractured plasma membranes, although fewer in number. surfaces exposed by etching possess a highly regular hexagonal array of pits 25 nm apart. by examining freeze-fra ... | 1973 | 4355859 |
| quantitation of mouse mammary tumor virus (mtv) virions by radioimmunoassay. | | 1973 | 4356324 |
| [breast cancer and virus]. | | 1973 | 4356437 |
| [editorial: viruses and breast cancers]. | | 1973 | 4356582 |
| transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains. | | 1973 | 4357097 |
| quantitative studies of oncornaviruses in thin sections. | | 1973 | 4357378 |
| comparison of three mammary tumor viruses in genetically similar susceptible mice. | | 1973 | 4357766 |
| cultivation and characterization of balb-cfc3h mammary tumor cell lines. | | 1973 | 4358145 |
| [viruses and mammary cancer. a survey (author's transl)]. | | 1973 | 4358520 |
| fusion of xc rat sarcoma cells induced by murine leukaemia virus-infected mouse mammary tumour cells. absence of interference by simultaneously synthesized mammary tumour virus. | | 1973 | 4359242 |
| primate and murine type-c viral nucleic acid association kinetics: analysis of model systems and natural tissues. | hybridization studies employing single-stranded (3)h-dna transcripts of type-c viruses isolated from a woolly monkey or gibbon ape failed to detect nucleic acid sequences homologous to these viruses in the dna from a variety of uninfected primate species. the possible significance of these results for the epidemiology of type-c viruses in primates is discussed. | 1974 | 4359298 |
| structure of the mouse mammary tumor virus: polypeptides and glycoproteins. | the polypeptide and glycoprotein compositions of the mouse mammary tumor virus virion from primary monolayer cultures of balb/cfc3h mouse mammary tumor cells were studied by polyacrylamide gel electrophoresis by using internal and external labeling and coomassie blue and periodic acid schiff (pas) staining. twelve polypeptides were reproducibly resolved by the combined methods. five major polypeptides were demonstrable with estimated molecular weights of 52,000, 36,000, 28,000, 14,000, and 10,00 ... | 1974 | 4359300 |
| studies on the interrelationship of type b and type c virus particles in breast cancer and in leukemia. | | 1973 | 4360177 |