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t1-weighted mr-lymphography after intramammary administration of gadomer-17 in pigs.to evaluate the enhancement of regional lymph nodes and lymphatic vessels after intramammary injection of gadomer-17.200211793281
gut luminal lactate release during gradual intestinal ischemia.gut ischemia induced by occlusion of the superior mesenteric artery (sma) results in release of lactate into the gut lumen. we studied the threshold of sma flow reduction that leads to increased gut luminal lactate during stepwise reduction in sma blood flow.200111797028
molecular phylogenetics relationship between six chinese native pig breeds and three swedish pig breeds from mitochondrial dna.mitochondrial dna genetic polymorphisms were used to evaluate the relationship between 6 chinese indigenous pig breeds and 3 swedish domestic pig breeds. a total of 440 bp of the control region and 798 bp of cytochrome b (cyt b) gene of mtdna were determined from 140 pigs of 9 different breeds. the results of phylogenetics analysis showed that 6 chinese native pig breeds originated from the asian wild boar. the pairwise nucleotide sequences divergence suggested that they might occur about 413,00 ...200111797341
optimizing ventilation in conjunction with phased chest and abdominal compression-decompression (lifestick) resuscitation.the best method for employment of phased chest and abdominal compression-decompression (lifestick) cardiopulmonary resuscitation (cpr) has yet to be determined. of particular concern with using this technique is the combining of ventilation with the phased compressions and decompressions. twenty domestic swine (50+/-1 kg) were equally divided into four groups. following 10 min of untreated vf, cpr was begun. group 1 received lifestick (ls) cpr with only passive ventilation ('passive'); group 2 r ...200211801354
optimizing timing of ventricular defibrillation.our intent was to evolve a prognosticator that would predict the likelihood that an electrical shock would restore a perfusing rhythm. such a prognosticator was to be based on conventional electrocardiographic signals but without constraints caused by artifacts resulting from precordial compression. the adverse effects of "hands off" intervals for rhythm analyses would therefore be minimized. such a prognosticator was further intended to reduce the number of electrical shocks and the total energ ...200111801840
[risk factors for human african trypanosomiasis in the bipindi region of cameroon].in the course of two surveys carried out at the end of 1998 and beginning of 1999, sleeping sickness was diagnosed in a total of 43 people in the bipindi region of cameroon. this observation led us to investigate the mechanisms of transmission of human african trypanosomiasis in the epicentrer of the outbreak. a case-control study showed a particularly high risk of infection associated with hunting activities (odds-ratio: 2.87; ci 95%: 0.96-9.52). interpretation of this finding in the light of l ...200111803830
unexpectedly high allelic diversity at the kit locus causing dominant white color in the domestic pig.mutations in kit encoding the mast/stem cell growth factor receptor (mgf) are responsible for coat color variation in domestic pigs. the dominant white phenotype is caused by two mutations, a gene duplication and a splice mutation in one of the copies leading to skipping of exon 17. here we applied minisequencing and pyrosequencing for quantitative analysis of the number of copies with the splice form. an unexpectedly high genetic diversity was revealed in white pigs. we found four different kit ...200211805065
diaspirin cross-linked hemoglobin fails to improve left ventricular diastolic function after fluid resuscitation from hemorrhagic shock.in severe hemorrhagic shock, left ventricular (lv) diastolic dysfunction is an early sign of cardiac failure due to compromised myocardial oxygenation. immediate fluid replacement or, in particular, administration of a hemoglobin-based oxygen carrier (diaspirin cross-linked hemoglobin; dclhb) improves myocardial oxygenation; therefore, positive effects on lv diastolic function could be expected. the effects of fluid resuscitation from severe hemorrhagic shock with dclhb were investigated in 20 a ...200111805391
clinical and experimental study on regional administration of phosphorus 32 glass microspheres in treating hepatic carcinoma.aim:to study the therapeutical effectiveness, dosage range and toxic adverse effects of domestic phosphorus 32 glass microsphere and evaluate its clinical significance.methods:i.fifty two balb/c tumor bearing male nude mice were allocated into treatment group(n = 38) and control group(n = 14). in the former group different doses of (32) p-gms were injected into the tumor mass, while in the latter (31)p-gms or no treatment was given. the experimental animals were sacrificed in batches, and then t ...199911819498
comparison of a new stent and wallstent for transjugular intrahepatic portosystemic shunt in a porcine model.to evaluate a new balloon-expandable stainless steel stent (cordis stent) in a transjugular intrahepatic portosystemic shunt (tips) porcine model and compared with wallstent.200111819736
simultaneous intra/extravascular administration of antiproliferative agents as a new strategy to inhibit restenosis: the peak of reactive cell proliferation as a hallmark for the duration of the treatment.strictly intravascular approaches for the treatment of postangioplasty restenosis are effective in the intima and the inner parts of the media but may be insufficient to control redundant pathways in the more outer parts of the media and the adventitia. an inverse situation may occur subsequently to a strictly extravascular approach, like the recently suggested pericardial approach in pigs. we hypothesized that simultaneous intra/extravascular administration of anti-restenotic agents inhibits re ...200211825339
pathogenesis of african swine fever virus in ornithodoros ticks.african swine fever virus (asfv) is the only known dna arbovirus and the sole member of the family asfarviridae. it causes a lethal, hemorrhagic disease in domestic pigs. asfv is enzootic in sub-saharan africa and is maintained in a sylvatic cycle by infecting both wild members of the suidae (e.g. warthogs) and the argasid tick ornithodoros porcinus porcinus. the pathogenesis of asfv in o. porcinus porcinus ticks is characterized by a low infectious dose, lifelong infection, efficient transmissi ...200111831434
characterization of trypanosoma brucei s.l. subspecies by isoenzymes in domestic pigs from the fontem sleeping sickness focus of cameroon.though it has been established that domestic animals (especially the pig) are potential reservoir hosts for trypanosoma brucei gambiense in west africa, there is little data to this effect concerning central africa. instead, some previous authors report the absence of trypanozoon type trypanosomes in domestic animals in cameroon. thirty-two domestic pigs were sampled by kivi (kit for in vitro isolation) of trypanosomes in the northern region (bechati) of the fontem sleeping sickness focus of cam ...200211835899
isolation of nipah virus from malaysian island flying-foxes.in late 1998, nipah virus emerged in peninsular malaysia and caused fatal disease in domestic pigs and humans and substantial economic loss to the local pig industry. surveillance of wildlife species during the outbreak showed neutralizing antibodies to nipah virus mainly in island flying-foxes (pteropus hypomelanus) and malayan flying-foxes (pteropus vampyrus) but no virus reactive with anti-nipah virus antibodies was isolated. we adopted a novel approach of collecting urine from these island f ...200211880045
transvaginal laparoscopic nephrectomy: development and feasibility in the porcine model.to assess feasibility of laparoscopic nephrectomy completed entirely by way of the vagina in the porcine model.200211880100
enterococcus faecium-related outbreak with molecular evidence of transmission from pigs to humans.between 24 july and 31 august 1998, thousands of domestic pigs died of hemorrhagic shock in three adjunct counties along the yangzi river in jiangshu province, china. from 28 july to 6 september 1998, 40 local farmers (36 males and 4 females, ages 23 to 78 years) were hospitalized with severe illness characterized by high fever, erythematous rash or petechiae, and profound lethargy after contact with sick pigs. twelve (30%) of these patients died of respiratory failure and shock. eleven bacteria ...200211880415
gadolinium containing contrast agents for pulmonary ventilation magnetic resonance imaging: preliminary results.five gadolinium containing contrast media (gadopentetate dimeglumine [magnevist; berlex imaging, montville, nj, usa], gadobutrol [gadovist; schering, järfälla, sweden], gadoteridol [prohance; bracco-byk gulden, konstanz, germany], gadobenate dimeglumine [multihance; bracco-byk gulden, konstanz, germany], and gadopentetate dimeglumine added with mannitol and a surface active detergent) were evaluated for their efficacy in magnetic resonance depiction of lung ventilation.200211882791
novel swine virulence determinant in the left variable region of the african swine fever virus genome.previously we have shown that the african swine fever virus (asfv) nl gene deletion mutant e70deltanl is attenuated in pigs. our recent observations that nl gene deletion mutants of two additional pathogenic asfv isolates, malawi lil-20/1 and pr4, remained highly virulent in swine (100% mortality) suggested that these isolates encoded an additional virulence determinant(s) that was absent from e70. to map this putative virulence determinant, in vivo marker rescue experiments were performed by in ...200211884534
vasopressinergic innervation of the pig pineal gland.an immunohistochemical study of the pineal gland of the domestic pig was carried out using the antisera raised against vasopressin (vp). the pineal glands were taken from the newborn, 21-day- and 7-month old female pigs. the pig pineal gland is moderately innervated by vp-immunoreactive nerve fibers. they run from the habenular commissure into the connective tissue septa and further into the pineal parenchyma. in the subependymal tissue as well as in the connective tissue septa, the fibers are s ...200211885805
ureteral segmental replacement using multilayer porcine small-intestinal submucosa.to assess the outcome of segmental ureteral replacement using a new multilayer porcine small-intestinal submucosa (sis), surgisis es (cook inc., stouffville, on, canada) designed to provide enhanced strength.200211890446
physiological and behavioral effects of different success during social confrontation in pigs with prior dominance experience.the impact of a 10-h social confrontation on behavior, plasma adrenaline, noradrenaline and cortisol was studied in 14 domestic pigs (eight castrated males and six females) with prior dominance experience. prior to the experiments, animal groups, each consisting of nine growing pigs (12 weeks old) from different litters, were composed randomly. after 5 days, the pig with the highest rank from each group was removed, provided with a jugular vein catheter and kept in single housing for 2-3 weeks. ...200211890961
the effects of varying degrees of allograft decalcification on cultured porcine osteoclast cells.demineralized freeze-dried bone allograft (dfdba) is widely used in periodontal therapy as a scaffold for new bone formation in periodontal defects. it is demineralized, theoretically, to expose osteoinductive or osteoconductive bone matrix proteins that should facilitate osteogenesis. the degree of dfdba demineralization varies between tissue banks and may affect clinical regeneration. a 2% residual calcium level in dfdba has been shown to result in the highest alkaline phosphatase activity lev ...200211895288
usefulness of human coagulation and fibrinolysis assays in domestic pigs.pigs are often used as animal models in research on blood coagulation and fibrinolysis. the usefulness of the assays applied within this field, and the knowledge of reference intervals are therefore essential and of utmost importance. in the study reported here, we investigated the applicability of commercial human coagulation and fibrinolysis assays for use with porcine plasma. in total, 22 functional and immunologic assays were applied to plasma obtained from domestic pigs, and the following b ...200211900411
comparison of thermal spread after ureteral ligation with the laparo-sonic ultrasonic shears and the ligasure system.the extent of lateral spread of tissue injury is important in the success of a primary anastomosis. we compared the injury produced by the laparo-sonic coagulation shears and the ligasure system.200211905864
use of absorbable cyanoacrylate glue to repair an open cystotomy.a biodegradable cyanoacrylate glue was tested for its ability to close bladder injuries in an established porcine model. inflammation and encrustation associated with this glue were examined in a rabbit model.200211912451
enhancement of primary stability of dental implants using cortical satellite implants.this study aims to assess the effect of satellite implants on the primary stability of dental implants placed in fresh extraction sites in vitro.200211915545
calibrated pneumoperitoneal venting to prevent n2o accumulation in the co2 pneumoperitoneum during laparoscopy with inhaled anesthesia: an experimental study in pigs.nitrous oxide (n2o) accumulates in the co2 pneumoperitoneum during laparoscopy when n2o is used as an adjuvant for inhaled anesthesia. this may worsen the consequences of gas embolism and introduce a fire risk. in this study, we quantified the pneumoperitoneal gas venting necessary to prevent significant contamination by inhaled n2o. four domestic pigs (26-30 kg) were anesthetized and ventilated with 66% n2o in oxygen. a co2 pneumoperitoneum was insufflated and maintained at a pressure of 12 mm ...200211916815
effects of birth season, breed, sex, and sire family on cardiac morphology determined in pigs (sus scrofa domestica) by use of echocardiography.echocardiography played an important role in the screening and diagnosis of hypertrophic cardiomyopathy. in the study reported here, we attempted to evaluate the effects of birth season, breed, sex, and sire family on cardiac morphology determined in pigs by use of echocardiography.200111924818
a newly designed vertebral replacement implant to reconstruct the thoracolumbar spine anteriorly.calcium phosphate compounds are becoming of increasingly great importance in the field of biomaterials and, in particular, as bone substitutes. in this way donor-side morbidity can be avoided. a type a lesion of the vertebral body can be the reason of a neurological deficit, requiring a corpectomy by means of an anterior approach, tricortical bone grafting and internal stabilization to get a fusion over time. it is our aim to introduce in this study a newly designed vertebral replacement device, ...200211925738
non-invasive measurement of blood pressures in the yucatan micropig (sus scrofa domestica), with and without midazolam-induced sedation.current literature suggests that the effects of midazolam, a water-soluble benzodiazepine, on blood pressure in swine are minimal. the hypothesis of the study reported here was that a light sedative dose would induce a decrease in blood pressure in this species. healthy female yucatan micropigs (n = 20), 16 to 30 (mean, 22) kg, aged four six months, were individually placed in a humane restraint sling and allowed to acclimate. systolic (sbp), diastolic (dbp), and mean (mbp) blood pressures (mmhg ...200111926295
parasitism of domestic swine (sus scrofa) by amblyomma ticks (acari: ixodidae) on a farm at monte negro, western amazon, brazil.abstract in january 2001, while conducting a survey of the tick fauna of the state of rondĵnia, brazil, a rural area within monte negro county was visited. on one farm within the county the producer maintained a herd of crossbred swine, sus scrofa l., that was reared under unconfined conditions, with unrestrained access to the pasture and adjacent native amazon equatorial forest. inspection of the swine herd produced a total of 77 ticks collected from eight adult pigs (mean, 9.6 ticks per pig) t ...200211931265
surgical experience with retroperitoneal heterotopic heart transplantation in the large white domestic swine.accelerated coronary atherosclerosis following heart transplantation is the main limiting factor for long-term survival, aside from graft failure and complications due to immunosuppression. graft coronary vasculopathy is due to chronic rejection of the vascular wall leading to intimal hyperplasia in coronary arteries. numerous heterotopic heart transplantation models have been used in different species to study the immunology and pathophysiology following graft implantation. this study reports o ...200211931494
plasmid vectors encoding cholera toxin or the heat-labile enterotoxin from escherichia coli are strong adjuvants for dna vaccines.two plasmid vectors encoding the a and b subunits of cholera toxin (ct) and two additional vectors encoding the a and b subunits of the escherichia coli heat-labile enterotoxin (lt) were evaluated for their ability to serve as genetic adjuvants for particle-mediated dna vaccines administered to the epidermis of laboratory animals. both the ct and the lt vectors strongly augmented th1 cytokine responses (gamma interferon [ifn-gamma]) to multiple viral antigens when codelivered with dna vaccines. ...200211932419
predicting the success of defibrillation by electrocardiographic analysis.we investigated an electrocardiographic signal analysis technique for predicting whether an electrical shock would reverse ventricular fibrillation (vf) in an effort to minimize the damaging effects of repetitive shocks during cpr.200211947983
expanding automatic external defibrillators to include automated detection of cardiac, respiratory, and cardiorespiratory arrest.the new guidelines of the american heart association state that lay rescuers can no longer rely on the manual pulse check to confirm cardiac arrest in an unresponsive patient. we were therefore prompted to develop a method for automated determination of the presence or absence of cardiac contraction and breathing. the technique was designed to be incorporated into conventional automated external defibrillators and to work in conjunction with the information derived from rhythm analyses by the au ...200211953646
seasonal patterns of arthropods occurring on sheltered and unsheltered pig carcasses in buenos aires province (argentina).differences in the succession of insects and other arthropoda (invertebrate animals with jointed legs), on domestic pig carcasses placed under a roof and under the open sky have been studied in buenos aires province, argentina (latitude 34 degrees 45's) in all the seasons of the year. faunal associations proved different for each treatment in winter: the common bluebottle calliphora vicina was found in both, but on the sheltered carcass cochliomyia macellaria and the rare phaenicia cluvia were f ...200211955835
robotically assisted minimally invasive biliary surgery in a porcine model.a robotic surgery system has the potential both to reduce the effects of tremor and fatigue and to enhance dexterity in the performance of complex, fine endosurgical tasks. we report a prospective study of robotically assisted minimally invasive biliary surgery in a porcine model using the zeus robotic surgical system (computer motion, goleta, ca, usa).200211961624
radiofrequency coagulation of renal parenchyma: comparison of effects of energy generators on treatment efficacy.we compared experimental renal lesions created with temperature-based or impedance-based radiofrequency (rf) generators using normal renal parenchyma in an animal model with protocols recommended by the manufacturer.200211962560
[age variation of the phenotypic expression and the inheritance of the igg system of immunoglobulin allotypes in the pig].the specificity of phenotypic expression and inheritance of immunoglobulin allotypes igg1a and igg2b in pigs are discussed. it was shown that a negative state by both these allotypes is repeatedly found among newborn pigs but is extremely rare in pigs older than one month. a model, which simultaneously describes the genetic determination of allogroups formed by allotypes igg1a and igg2b and the dynamics of ontogenetic expression of individual genotype by system igg with a result of a visually re ...200211963565
national serologic survey for trichinellosis in sows in canada 1996-1997.sera from 14,408 market sows from the canadian domestic swine herd were tested for trichinellosis using an indirect-elisa as a screening test and a competitive elisa for confirmatory testing. three sera (0.02%) gave low level reactions on the competitive elisa. these reactions were considered nonspecific, and this designation was supported by data from previous and subsequent national surveys, in which serologic, trichinoscopic, and digestion test methodologies was used. this study provides addi ...200211963660
comparison of different methods for measuring intra-abdominal pressure.intra-abdominal pressure (iap) can be measured in different ways but is usually measured indirectly via the urinary bladder. the aim of the study was to: 1) compare urinary bladder pressure, femoral vein pressure, and inferior caval vein pressure with iap at different levels of iap; and 2) try to find an optimal amount of fluid to be instilled into the urinary bladder before measurement of the bladder pressure, and to compare changes in blood flow in the femoral vein with that in the caval vein ...200211967609
x-ray digital subtraction angiography with 1 mol/l gadobutrol: results from a comparative porcine study with iodinated contrast agents.to evaluate prospectively diagnostic accuracy of 1 mol/l gadobutrol as a contrast agent for intraarterial x-ray digital subtraction angiography (dsa) in comparison to iodinated, nonionic contrast media and 0.5 mol/l gadolinium-dtpa.200211979151
toxoplasma gondii myosin a and its light chain: a fast, single-headed, plus-end-directed motor.successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. toxoplasma gondii penetrates host cells by an active process involving its own actomyosin system and which is distinct from induced phagocytosis. toxoplasma gondii myosin a (tgmyoa) is presumed to achieve power gliding motion and host cell penetration by the capping of apically released adhesins towards the rear of the parasite. we report here an exten ...200211980712
chronic endothelin receptor antagonism prevents coronary vasa vasorum neovascularization in experimental hypercholesterolemia.the purpose of this study was to test the hypothesis that endothelin (et) receptor antagonism reduces coronary vasa vasorum neovascularization in experimental hypercholesterolemia.200211985922
evaluation of the genetic variability of 13 microsatellite markers in native indian pigs.we analysed polymorphism of 13 microsatellites in two indian domesticated pig types (north indian and northeast indian). heterozygosity, polymorphism information content, and probability of identity of two random individuals were calculated for all microsatellites in both types. the number of alleles observed at a locus varied between five and 12. the evaluated microsatellites exhibited a very high heterozygosity and polymorphism information content. the probability of identity of two random ind ...200111988634
a new bipolar feedback-controlled sealing system for closure of the cystic duct and artery.bile leaks are serious complications after laparoscopic cholecystectomy. the aim of this study was to evaluate the feasibility of closure of the cystic duct with a new feedback-controlled bipolar sealing system (ligasure).200211997828
the role of approximate entropy in predicting ventricular defibrillation threshold.the role of myocardial tissue mass on ventricular defibrillation threshold (dft) is unclear. we hypothesized that changes in tissue mass modulate dft by changing ventricular fibrillation (vf) wavefront regularity (entropy).200212000978
stress response to cold in trichinella species.trichinella-type larvae (l(1)) are found in the muscles of infected wild animals and domestic pigs and are the cause of trichinosis in man and other animals throughout the world. these parasites are exposed to low temperatures during their life cycle. on this premise, three trichinella species of different types of habitat (the arctic t. nativa, the cosmopolitan t. spiralis, and the tropical t. nelsoni) were selected to examine the effect of a shift in temperature, from 37 to 4 degrees c, on lon ...200112009726
site-specific percutaneous absorption of methyl salicylate and vx in domestic swine.the site specificity of the percutaneous absorption of methyl salicylate (mes) and the organophosphate nerve agent vx (o-ethyl s-(2-diisopropylaminoethyl) methylphosphonothioate) was examined in anaesthetized domestic swine that were fully instrumented for physiological endpoints. four different anatomical sites (ear, perineum, inguinal crease and epigastrium) were exposed to the mes and the serum levels were measured over a 6-h time period. the dose absorbed at the ear region was 11 microg cm(- ...200212015792
presynaptic autoregulation of norepinephrine release from the sympathetic nerve fibers in the pineal gland of the domestic pig. pharmacological characterization of alpha(2)adrenoceptors mediating this process.norepinephrine is the main neurotransmitter controlling melatonin secretion in the mammalian pineal gland. presynaptic autoregulation of norepinephrine release from the sympathetic nerve fibers in the pineal gland is poorly known.200212019363
genomic characterization of tt viruses (ttvs) in pigs, cats and dogs and their relatedness with species-specific ttvs in primates and tupaias.using pcr with primers derived from a non-coding region of the human tt virus (ttv) genome, the ttv sequence in serum samples obtained from pigs (sus domesticus), dogs (canis familiaris) and cats (felis catus) was identified and the entire genomic sequence was determined for each representative isolate. three ttv isolates (sd-ttv31 from a pig, cf-ttv10 from a dog and fc-ttv4 from a cat) comprising 2878, 2797 and 2064 nucleotides, respectively, each had three open reading frames (orfs) encoding 4 ...200212029143
identification of the principal serological immunodeterminants of african swine fever virus by screening a virus cdna library with antibody.protective immunity to african swine fever virus (asfv) may involve a combination of both serological and cellular mechanisms. this work is focused on the identification of the possible relevant serological immunodeterminants of immunity. thus, 14 serological immunodeterminants of asfv have been characterized by exhaustive screening of a representative lambda phage cdna expression library of the tissue culture-adapted ba71v strain of asfv. the library was constructed using rna extracted from ver ...200212029148
lack of effect of conduction direction on action potential durations in anisotropic ventricular strips of pig heart.the influence of activation sequence on the rate of rise of the depolarization phase of action potentials in atrial or ventricular muscles has been well established. however, whether myocardial fiber orientation is important in modulating the repolarization process is unclear.200212033356
argon ion beam hemostasis with albumin after liver resection.bleeding is common after liver resection and establishing hemostasis with sutures or argon beam coagulation can be difficult. in our laboratory, concentrated albumin applied to the liver surface before argon beam coagulation improves sealing of the resected surface of the liver, including closure of blood vessels and ducts not generally seen with standard argon beam coagulation.200212034399
molecular variation of taenia solium in the world.complete nucleotide sequences of the mitochondrial cytochrome b (cytb) and cytochrome c oxidase subunit i (co i) genes from various isolates of taenia solium were examined. eleven isolates were analyzed; two isolates from china, two isolates from indonesia, one isolate each from india, thailand, mexico, ecuador, peru, mozambique and tanzania. in both genes, two isolates from indonesia shared the same sequences. similarly, the isolate from mexico shared same sequences with that from peru, and the ...200112041611
use of fan beam dual energy x-ray absorptiometry to measure body composition of piglets.a piglet model was used to determine whether the fan beam dual energy x-ray absorptiometry technique (dxa) could be adapted for the measurement of body composition of small subjects. commercial domestic swine piglets (n = 14) with weights between 1.95 and 21.1 kg had duplicate fan beam-dxa scans followed by chemical analysis of body composition. each scan required 2-3 min to complete. dxa-measured total body weight was validated against scale weights of the piglets (with and without blanket and ...200212042462
does cortisol bias cytokine production in cultured porcine splenocytes to a th2 phenotype?glucocorticoids are reported to bias the production of cytokines from a type 1 to a type 2 phenotype. however, this dogma has been advanced largely from studies utilizing potent glucocorticoid analogs, particularly dexamethasone (dex). although studies utilizing dex certainly have clinical and pharmacological relevance, dex is probably not the best glucocorticoid for studies designed to evaluate the interaction and regulation of endogenous corticosteroids with immune cells in vivo in the domesti ...200212072272
vasopressin improves survival in a pig model of hypothermic cardiopulmonary resuscitation.during hypothermic cardiopulmonary resuscitation with a body core temperature <30 degrees c administration of a vasopressor to support coronary perfusion pressure is controversial. the purpose of the current study was to assess the effects of a single 0.4-unit/kg dose of vasopressin on coronary perfusion pressure, defibrillation success, and 1-hr survival in a pig model of hypothermic closed-chest cardiopulmonary resuscitation combined with rewarming.200212072687
impact of jpeg lossy image compression on quantitative digital subtraction radiography.the aim of the study was to evaluate the impact of jpeg lossy image compression on the estimation of alveolar bone gain by quantitative digital subtraction radiography (dsr).200212076050
distribution and density of medium- and short-wavelength selective cones in the domestic pig retina.the topography of medium (m)- and short (s)-wavelength sensitive cone photoreceptors was studied in the domestic pig retina. antisera specific for m or s opsin as well as cone photoreceptor proteins arrestin and alpha-transducin were used to label cone types. retinal wholemounts and their blood vessel patterns were drawn and specific regions removed. the wholemounts were immunocytochemically labelled to detect both m and s cones, and the specific regions labelled to detect s cones. cones were co ...200212076087
mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects.a novel therapeutic option for the treatment of acute myocardial infarction involves the use of mesenchymal stem cells (mscs). the purpose of this study was to investigate whether implantation of autologous mscs results in sustained engraftment, myogenic differentiation, and improved cardiac function in a swine myocardial infarct model.200212078791
a selective alpha(2)-adrenergic agonist for cardiac resuscitation.the effects of selective alpha(2)-adrenergic agonist alpha-methylnorepinephrine on the initial success of resuscitation and postresuscitation myocardial function were compared with nonselective alpha- and beta-adrenergic epinephrine in a swine model of cardiac arrest. epinephrine, the primary pharmacological intervention in the treatment of cardiac arrest, improves immediate outcome. however, epinephrine increases the severity of myocardial dysfunction after cardiac resuscitation. both inotropic ...200212080325
cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. estimation of their incidence in french populations.eight new cases of reciprocal translocation in the domestic pig are described. all the rearrangements were highlighted using gtg banding techniques. chromosome painting experiments were also carried out to confirm the proposed hypotheses and to accurately locate the breakpoints. three translocations, rcp(4;6)(q21;p14), rcp(2;6)(p17;q27) and rcp(5;17)(p12;q13) were found in boars siring small litters (8.3 and 7.4 piglets born alive per litter, on average, for translocations 2/6 and 5/17, respecti ...200212081804
influence of age on the electrocardiographic waves in taiwanese lan-yu miniature pigs.the purpose of the study reported here was to determine baseline information of the electrocardiogram (ecg) and the influence of age on cardiac function in taiwanese lan-yu (tly) miniature pigs. non-anesthetized tly minipigs (from birth to 6 months of age) were placed on a webbed stanchion, simulating a standing position, for acquisition of an ecg, using six limb leads (i, ii, iii, avr, avl, and avf), with each as a single-channel ecg recorder. the p and t waves obtained from leads i, iii, and a ...199912086414
effects of ketamine-xylazine and isoflurane on insulin sensitivity in dehydroepiandrosterone sulfate-treated minipigs (sus scrofa domestica).isoflurane and ketamine-xylazine (kx) combinations are widely used veterinary anesthetics, kx being the particularly common agent for immobilizing swine. results of previous studies indicate that kx and xylazine suppress insulin release. the steroid hormones, dehydroepiandrosterone (dhea) and its sulfated form, dehydroepiandrosterone-sulfate (dheas), have variable effects on insulin sensitivity in animals. we evaluated the effect of dheas on plasma glucose and insulin concentrations in female yu ...200212102568
treatment of post resuscitation myocardial dysfunction: aortic counterpulsation versus dobutamine.post resuscitation myocardial stunning is well described and recognized as a significant contributor to poor long-term outcome following cardiac arrest. optimal strategies for treatment have not been determined.200212104111
prehistoric introduction of domestic pigs onto the okinawa islands: ancient mitochondrial dna evidence.ancient dnas of sus scrofa specimens excavated from archaeological sites on the okinawa islands were examined to clarify the genetic relationships among prehistoric sus scrofa, modern wild boars and domestic pigs inhabiting the ryukyu archipelago, the japanese islands, and the asian continent. we extracted remain dna from 161 bone specimens excavated from 12 archaeological sites on the okinawa islands and successfully amplified mitochondrial dna control region fragments from 33 of 161 specimens. ...200212107598
apparent cross-infection with a single strain of malassezia pachydermatis on a pig farm.twenty-nine isolates of malassezia pachydermatis were recovered from a single farm of 100 pigs in croatia. in contrast, 290 farm pigs from other locations (northern parts of croatia and slovenia) yielded only two non-lipid dependent isolates of m. pachydermatis using the same swabbing procedure. ten of the 29 isolates from a single farm had their identity confirmed by karyotyping, and were typed by restriction fragment length polymorphism (rflp) analysis. all but one of these isolates sub-typed ...200212113169
c-fos mrna expression associated with pgf(2alpha)-induced nest-building behaviour in female pigs.domestic pigs, sus scrofa, build a maternal nest on the day before parturition. a model for nest building has been established in pigs, in which exogenously administered prostaglandin (pg) f(2alpha) may be used to elicit nesting behaviour in cyclic, pseudopregnant and pregnant pigs. the central mechanisms mediating this response are unknown. the present study determined regional brain activity using semi-quantitative analysis of c-fos mrna, after induction of nest-building behaviour by pgf(2alph ...200212117548
adverse outcomes of interrupted precordial compression during automated defibrillation.current versions of automated external defibrillators (aeds) require frequent stopping of chest compression for rhythm analyses and capacity charging. the present study was undertaken to evaluate the effects of these interruptions during the operation of aeds.200212119255
a 24-h pneumoperitoneum leads to multiple organ impairment in a porcine model.background: an intra-abdominal pressure (iap) of 15 mm hg reduces intestinal organ perfusion in humans and animals, but it is unknown whether this results in organ damage. the purpose of this study was to evaluate if an iap of 15 mm hg lasting for 24 h in a porcine model will lead to morphologic impairment of intestinal and adjacent organs. methods: we examined 12 intubated and anesthetized domestic pigs (51.8 +/- 4.4 kg). using co2 pneumoperitoneum, the iap was raised to 15 mm hg (study group, ...200212127806
regional variation in myocardial water content in the edematous pig heart.the purpose of this study was to examine regional variation in myocardial water content (%mwc) throughout the iatrogenically edematous pig heart.200212127810
beta-cyclodextrin tetradecasulfate, a novel cyclic oligosaccharide, inhibits thrombus and neointimal formation after coronary vascular injury.neointimal formation is a major cause of restenosis after interventional vascular procedures. beta-cyclodextrin tetradecasulfate (beta-cdt) has been shown to inhibit fibroblast growth factor activity and we hypothesized that beta-cdt would reduce intimal formation.200212131024
comparison of pulsatile and nonpulsatile perfusion of the lung in an extracorporeal large animal model.extracorporeal lung-perfusion models are widely used to evaluate pulmonary preservation techniques and reperfusion injury. however, these models mainly depend on nonpulsatile flow, which is not physiological and can subsequently lead to pulmonary edema. observation in a standardized setting and reliability of functional and structural data assessment are therefore limited. to overcome these limitations we developed a new extracorporeal large animal lung perfusion model utilizing pulsatile flow t ...200212145559
radioactive 133-xenon gas-filled balloon to prevent restenosis: dosimetry, efficacy, and safety considerations.ionizing radiation administered intraluminally via catheter-based systems using solid beta and gamma sources or liquid-filled balloons has shown reduction in the neointima formation after injury in the porcine model. we propose a novel system that uses a 133-xenon (133xe) radioactive gas-filled balloon catheter system.200212163434
cerebral veno-arterial pco2 difference as an estimator of uncompensated cerebral hypoperfusion.the aim of the present study was to assess the veno-arterial difference in pco2 (delta pco2) as an indicator of ischemia compared to the arteriovenous o2 difference (avdo2). staircase cerebral blood flow (cbf) reductions were obtained in seven domestic pigs by inducing intracranial hypertension: cbf 100%, 50-60% of baseline, 20-30% of baseline. icp, map, cpp and cbf (laser-doppler method) were continuously recorded. the superior sagittal sinus was punctured to determine avdo2 and delta pco2. avd ...200212168304
trichinella britovi in domestic pig--a case report. 200212173503
thoracoscopic internal mammary sentinel node biopsy: an animal model of a new technique.the nodal status remains the most important prognostic factor in breast cancer. while evaluation of the axillary lymph nodes remains a standard of practice, evaluation of the internal mammary lymph nodes is no longer routinely performed. in the era of extensive radical mastectomies, it was shown that up to 40% of breast cancer patients had nodal metastases in the internal mammary chain. this resulted in up to 10% of presumed "node-negative" patients actually being node-positive when the internal ...200212175975
hormonal changes related to reduced renal blood flow and low urine output under prolonged increased intra-abdominal pressure in pigs.to investigate effects of prolonged increased intra-abdominal pressure (iap) on diuresis, renal blood flow, and hormones that influence renal function, in particular endothelin.200212182244
effectiveness of radioactive tungsten source in the prevention of restenosis in stented porcine coronary arteries.intracoronary radiation has shown the potential to inhibit neointimal proliferation in porcine models of restenosis. the objective of this study was to determine whether intracoronary radiation using a new coiled wire of tungsten-188 ((188)w), a pure beta emitter (half-life 69.4 days) is safe. in addition, a dose of 0 gy, 18 gy, or 25 gy prescribed to 2 mm from the center of the source and delivered intraluminally is sufficient to prevent restenosis and free from adverse effects.200212182999
immunophenotyping of leukocyte subsets in peripheral blood and palatine tonsils of prefattening pigs.the quantitative and distribution patterns of porcine peripheral blood and tonsillar lymphoid/myeloid cell subsets were assessed in order to establish the immune status of farm pigs prior to their transfer to fattening units. peripheral blood and tonsillar samples were taken from clinically healthy, nonvaccinated, 12-week-old pigs, either ex vivo or following euthanasia. single-colour flow cytometry, using monoclonal antibodies (mabs) reactive with the swine leukocyte cluster of differentiation ...200212184498
[investigation on contraction mechanism of expanded tissue].to investigate the contraction mechanism of expanded tissue.200212189708
splanchnic and pancreatic tissue perfusion in experimental acute pancreatitis.gut hypoperfusion has a major role in the pathogenesis of multiple organ failure, which is the main cause of death in severe acute pancreatitis. the effects of experimental acute pancreatitis on splanchnic and pancreatic perfusion and oxygenation were studied to find out whether gut hypoperfusion occurs already at the same time as changes in pancreatic perfusion.200212190101
interposition of a jejunal segment as an alternative one-stage operation for acute left colon obstruction.much debate surrounds the one-stage surgical management of acute left colon obstruction. many surgeons are still reluctant to perform primary anastomosis in unprepared bowel fearing the risk of anastomotic dehiscence. although intraoperative lavage and subtotal colectomy have recently proved effective for preventing fecal loading, both of these procedures have drawbacks and the search for additional alternative surgical procedures continues. we conducted an experimental study to examine a new on ...200212203059
effects of hypertonic saline on myocardial blood flow in a porcine model of prolonged cardiac arrest.to evaluate the effects of hypertonic saline (hs) on myocardial reperfusion pressure (mpp) and blood flow (mbf), and cardiac index (ci) during and after cardiopulmonary resuscitation (cpr).200212204461
effect of inhaled endotoxin on cardiopulmonary function and e-selectin expression in pigs.to evaluate the effect of controlled exposure to inhaled lipopolysaccharides (lps) on the pulmonary inflammatory response of anesthetized pigs.200212224865
evolution of the stone heart after prolonged cardiac arrest.we hypothesized that progressive impairment in diastolic function during cardiopulmonary resuscitation (cpr) precedes evolution of the "stone heart" after failure of cpr. we therefore measured sequential changes in left ventricular (lv) volumes and free-wall thickness of the heart during cpr in an experimental model.200212226047
influence of development factors on nutritional patterns in the solomon islands.looks at the general changes brought about by development, and how the nutritional habits of the solomon island communities have been affected by development. the development aspirations of third world countries include the introduction of cash crops for foreign exchange; moving away from subsistence-type economy and self-reliance in feeding one's family to dependence on outside sources; employment of more people at salaried jobs, small industries and factories; and modernization. many governm ...198112265890
pulmonary gas exchange after cardiopulmonary resuscitation with either vasopressin or epinephrine.it is well established that epinephrine administered during cardiopulmonary resuscitation results in pulmonary gas exchange disturbances. it is uncertain how vasopressin affects gas exchange after cardiopulmonary resuscitation.200212352041
cellular and vascular reactions in the liver to radio-frequency thermo-ablation with wet needle applicators. study on juvenile domestic pigs.the aim of this animal experiment was to investigate the cellular and vascular reactions in the liver of juvenile domestic pigs produced by a radio-frequency thermoablation (rfta) applicator perfused with saline solution.200212364820
a review of mutual transmission of important infectious diseases between livestock and wildlife in europe.oral vaccination of red foxes against rabies has been practiced in europe since 1978 and has succeeded in greatly reducing the occurrence of this disease in foxes: this is an example of coordinated activity against a disease that affects both wild and domestic animals as well as humans. some examples of diseases that affect both domestic and wild animals in europe are: classical swine fever (hog cholera) in wild boars and domestic swine; myxomatosis and rabbit hemorrhagic disease in domestic and ...200212381556
the axillocoronary bypass. blood flow and short-term graft histology in a porcine model.bypass grafts arising from the axillary artery may be indicated for complications during minimally invasive direct coronary artery bypass grafting, for redo operations and for management of a severely atherosclerotic ascending aorta. as basic data research on this technique is scanty, we investigated intraoperative function and postoperative morphology of axillocoronary bypass grafts in a porcine model.200212386573
a porcine model of the abdominal compartment syndrome.the purpose of this study was to investigate whether an intra-abdominal pressure (iap) of 30 mmhg lasting 24 h in a porcine model will lead to a condition comparable with the abdominal compartment syndrome (acs) in humans. we examined 12 intubated and anesthetized domestic pigs with a mean body weight of 52.5 +/- 4.9 kg. using a co2 pneumoperitoneum, the iap was increased to 30 mmhg (study group, n = 6) for an investigation period of 24 h. in the control group, the iap remained unchanged. invest ...200212392274
after the 'affluent society': cost of living in the papua new guinea highlands according to time and energy expenditure-income.what is the cost of living in the papua new guinea highlands? an answer is sought using a time and energy accounting approach. the subsistence regime of wola-speaking highlanders, the subjects of this investigation, comprises three components. the principal one is horticulture: people clearing gardens from forest and grassland, with tuberous crops predominating, notably sweet potato. the second component comprises animal rearing, notably of domestic pigs. the third, and least important, is hunti ...200212395862
renal hypothermia achieved by retrograde intracavitary saline perfusion.hypothermia during vascular clamping protects the kidney from ischemia-induced nephron loss. traditionally, cooling is achieved by packing the kidney in ice, which lowers the temperature of the rest of the surgical field as well, and the method cannot be used during laparoscopy. we evaluated the utility of a newly developed ureteral access system for circulating ice-cold saline.200212396435
temporal relationship of hippocampal liquor- and plasma-cortisol-concentrations in the domestic pig challenged with synthetical adreno-corticotrophic hormone.the concentration of plasma and intracerebral cortisol in pigs challenged with 0.5 iu adrenocorticotrophic hormone/kg body weight was simultaneously measured at a 30 min rate. the pigs (n=5) were provided with indwelling jugular vein catheters and guide canullas for insertion of a hippocampal microdialysis probe. every five blood samples taken at 6 min intervals were pooled to simulate the 30 min collection time of the microdialysis. stimulation resulted in an increment of cortisol of roughly 20 ...200212419495
a porcine coronary stent model of increased neointima formation in the left anterior descending coronary artery.clinical trials suggest an increased frequency of restenosis after coronary intervention in left anterior descending (lad) compared to the left circumflex or right coronary arteries. experimental studies correlate stent-induced arterial injury and the extent of neointima formation. this study investigates whether the coronary artery affects the relationship between arterial injury and neointima hyperplasia in the porcine stent model.200212426824
aggressive venous neointimal hyperplasia in a pig model of arteriovenous graft stenosis.vascular access dysfunction is the most important cause of morbidity and hospitalization in the hemodialysis population in the united states at a cost of well over one billion dollars per annum. venous neointimal hyperplasia characterized by stenosis and subsequent thrombosis, is the major cause of polytetrafluoroethylene (ptfe) dialysis graft failure. despite the magnitude of the problem, there are currently no effective therapies for the prevention or treatment of venous neointimal hyperplasia ...200212427156
therapeutic effects of cooling swine skin exposed to sulfur mustard.recent world events have highlighted the need for effective medical therapies for chemical weapon injuries. of the chemical weapon agents, perhaps one of the most widely used, both historically and most recently in the iran-iraq war, is sulfur mustard (hd). no effective antidotes exist for this vesicant agent and, to this day, hd casualties are treated entirely symptomatically. previous work carried out in this laboratory has indicated that cooling hd-exposed tissue may ameliorate the resultant ...200212448623
in vivo study of bacterial adhesion to five types of intraocular lenses.to determine in vivo behavior of the ability of the staphylococcus epidermidis strain (american type culture collection [atcc] 14990) to attach to 120 intraocular lenses (iols) made of five different biomaterials: fluorine polymethylmethacrylate (pmma), heparinized pmma, silicone, hydrophobic acrylic, and hydrogel. the pig was chosen as an animal model of endophthalmitis, after a bibliographical analysis and a personal study of its aqueous humor composition.200212454042
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