| bacterial models for tumor development. mini-review. | the tumor-inducing effects of agrobacterium, bartonella and helicobacter bacterial species are compared step by step. an analogy for the existence of these individual steps is considered in connection with the development of cancer. the transformations of eukaryotic cells occur in particular in the type iv secretion system, i.e. involving the simultaneous transmission of dna and protein from bacterial cells to eukaryotic cells. thus, transfected cells facilitate the indefinite growth of tissue c ... | 2004 | 15571072 |
| seroprevalence of bartonella henselae and bartonella quintana infections in children from central and northern jordan. | to investigate the prevalence of antibodies to bartonella henselae (b.henselae) and bartonella quintana (b.quintana) among children from central and northern jordan. | 2004 | 15573198 |
| nationalism, carrión's disease and medical geography in the peruvian andes. | during the turn of the 20th century medical geography in peru concentrated in the study of a native disease (bartonellosis, also known as carrión's disease and verruga peruana) and reinforced the relationship between the country's 'natural' regions (coast, highlands and amazon) and different patterns of disease. expert knowledge on these themes was portrayed as important not only for the practice of medicine but also for the development of the country. this knowledge was instrumental for an emer ... | 2003 | 15584200 |
| the bartonella henselae sucb gene encodes a dihydrolipoamide succinyltransferase protein reactive with sera from patients with cat-scratch disease. | bartonella henselae is a recently recognized pathogenic bacterium associated with cat-scratch disease, bacillary angiomatosis and bacillary peliosis. a recombinant clone expressing an immunoreactive antigen of b. henselae was isolated by screening a genomic dna cosmid library by western blotting with sera pooled from patients positive for b. henselae igg antibodies by indirect immunofluorescence (ifa). the deduced amino acid sequence of the 43.7 kda encoded protein was found to be 76.3 % identic ... | 2004 | 15585501 |
| ddei rflp for 16s rdna typing in bartonella henselae. | | 2004 | 15585508 |
| late onset of serologic positive titers in a patient with parinaud's oculoglandular syndrome. | to report a case of parinaud's oculoglandular syndrome (pos) in which, despite the initially negative, a late onset of serologic positive titers was observed. | 2004 | 15590554 |
| demonstration of intracellular microorganisms (rickettsia spp., chlamydia pneumoniae, bartonella spp.) in pathological human aortic valves by pcr. | rickettsiae, which causes vasculitis, has not been linked to atherosclerotic cardiovascular disease in contrast to chlamydia pneumoniae whose association with coronary artery disease and with sclerotic heart valves in patients undergoing aortic valve replacement is well established, even if causality is yet to unproven. in the search for any of these infectious agents, 84 pathological and 15 normal aortic heart valves of patients undergoing forensic autopsy were analysed by pcr and dna-sequencin ... | 2005 | 15603840 |
| guidelines for the diagnosis of tick-borne bacterial diseases in europe. | ticks are obligate haematophagous acarines that parasitise every class of vertebrate (including man) and have a worldwide distribution. an increasing awareness of tick-borne diseases among clinicians and scientific researchers has led to the recent description of a number of emerging tick-borne bacterial diseases. since the identification of borrelia burgdorferi as the agent of lyme disease in 1982, 11 tick-borne human bacterial pathogens have been described in europe. aetiological diagnosis of ... | 2004 | 15606643 |
| evidence of bartonella sp. in questing adult and nymphal ixodes ricinus ticks from france and co-infection with borrelia burgdorferi sensu lato and babesia sp. | ticks are known vectors for a wide range of pathogenic microorganisms. their role in the transmission of some others is so far only suspected. ticks can transmit multiple pathogens, however, little is known about the co-existence of these pathogens within questing ticks. we looked for the presence of dna from three micro-organisms, bartonella sp., borrelia burgdorferi sensu lato and babesia sp. which are known or suspected tick-borne pathogens, using a cohort of 92 questing ixodes ricinus ticks ... | 2005 | 15610725 |
| bartonella henselae inhibits apoptosis in mono mac 6 cells. | bartonella henselae causes the vasculoproliferative disorders bacillary angiomatosis and peliosis probably resulting from the release of vasculoendothelial growth factor (vegf) from infected epithelial or monocytic host cells. here we demonstrate that b. henselae in addition to vegf induction was also capable of inhibiting the endogenous sucide programme of monocytic host cells. our results show that b. henselae inhibits pyrrolidine dithiocarbamate (pdtc)-induced apoptosis in mono mac 6 cells. b ... | 2005 | 15617526 |
| bartonella bovis in cattle in africa. | | 2004 | 15627528 |
| neck abscess secondary to cat-scratch disease. | a 7-year-old boy was referred to us for evaluation of an enlarging neck mass. the results of his primary care physician's initial clinical examination suggested lymphadenopathy secondary to lymphadenitis, and the patient was treated over a 4-week period with two rounds of antibiotics. however, the mass did not resolve, and it subsequently became fluctuant. the patient was referred to our institution, where we diagnosed cat-scratch disease. | 2004 | 15628637 |
| antibodies reactive with bartonella henselae and ehrlichia canis in dogs from the communal lands of zimbabwe. | the prevalences of antibodies against bartonella henselae and ehrlichia canis were determined in sera from 228 dogs in 5 communal lands of zimbabwe, areas where traditional subsistence agro-pastoralism is practised. the sera were collected from apparently healthy dogs during routine rabies vaccination programmes and tested with indirect fluorescent antibody assays using b. henselae (houston-i) and e. canis (oklahoma) as antigens. we found reactive antibodies (> or =1:80) against b. henselae in 1 ... | 2004 | 15628802 |
| bartonella henselae infection presenting as a unilateral panuveitis simulating vogt-koyanagi-harada syndrome. | to report an unusual ocular manifestation of cat scratch disease. | 2004 | 15629311 |
| visual loss after cat scratch. | | 2005 | 15632237 |
| multispacer typing technique for sequence-based typing of bartonella quintana. | bartonella quintana is a worldwide fastidious bacterium of the alphaproteobacteria responsible for bacillary angiomatosis, trench fever, chronic lymphadenopathy, and culture-negative endocarditis. the recent genome sequencing of a b. quintana isolate allowed us to propose a genome-wide sequence-based typing method. to ensure sequence discrimination based on highly polymorphic areas, we amplified and sequenced 34 spacers in a large collection of b. quintana isolates. six of these exhibited polymo ... | 2005 | 15634949 |
| pcr detection of bacteria on cardiac valves of patients with treated bacterial endocarditis. | we used broad-range pcr amplification and sequencing to detect and identify bacterial dna in 156 valves of patients treated for infective endocarditis (ie). bacterial dna was found more frequently in patients who underwent valve replacement while on antibiotic treatment for ie (60%) than in patients who had completed antibiotic treatment for ie (37%; p = 0.02). we found specific bacterial dna in valves removed from 11 of 30 patients who had completed antibiotic treatment for ie. six had no histo ... | 2005 | 15634966 |
| [bartonella and bartonellosis--emerging and re-emerging infections. taxonomy, bacteriology, pathogenesis and genetics]. | the review updates knowledge on the taxonomy, bacteriology and genetics of bartonella as well as pathogenesis of bartonellosis. the role of bartonella in human pathology, formerly considered to be rather modest, causes now growing anxiety. in this connection bartonella are now believed to be the causative agents of so-called emerging and re-emerging diseases, i.e. diseases, formerly unknown to man, and diseases, believed to be eradicated and playing at present no important role in human patholog ... | 2004 | 15636157 |
| molecular genetic methods for the diagnosis of fastidious microorganisms. | technological innovations in the detection and identification of microorganisms using molecular techniques such as polymerase chain reaction (pcr) have ushered in a new era with respect to diagnostic microbiology. pcr using universal or specific primers followed by identification of amplified product, mainly by sequencing, has enabled the rapid identification of cultured or uncultured bacteria. thus, pcr may allow quick diagnosis of infections caused by fastidious pathogens for which culture cou ... | 2004 | 15638838 |
| a bipartite signal mediates the transfer of type iv secretion substrates of bartonella henselae into human cells. | bacterial type iv secretion (t4s) systems mediate the transfer of macromolecular substrates into various target cells, e.g., the conjugative transfer of dna into bacteria or the transfer of virulence proteins into eukaryotic host cells. the t4s apparatus virb of the vascular tumor-inducing pathogen bartonella henselae causes subversion of human endothelial cell (hec) function. here we report the identification of multiple protein substrates of virb, which, upon translocation into hec, mediate al ... | 2005 | 15642951 |
| ectoparasitism and vector-borne diseases in 930 homeless people from marseilles. | homeless people are particularly exposed to ectoparasites, but their exposure to arthropod-borne diseases has not been evaluated systematically. a medical team of 27 persons (7 nurses, 6 infectious disease residents or fellows, 2 dermatologists, and 12 infectious disease specialists) visited the 2 shelters in marseilles, france, for 4 consecutive years. homeless volunteers were interviewed, examined, and received care; and blood was sampled for cell counts and detection of bacteremia, antibodies ... | 2005 | 15643300 |
| culture-negative bartonella endocarditis in a patient with renal failure: the value of molecular methods in diagnosis. | members of the genus bartonella are increasingly recognised as a cause of culture-negative endocarditis, particularly in those patients with underlying risk factors (e.g., homelessness and alcoholism (b. quintana) or valvulopathy and cat ownership (b. henselae). the aortic and mitral-valves are most commonly involved. here, a case is reported of culture-negative right-sided endocarditis, without any of the above risk factors, due to bartonella sp. in a 69-year-old man who presented with acute re ... | 2004 | 15649011 |
| molecular detection of bartonella spp. in the dental pulp of stray cats buried for a year. | bartonella henselae causes chronic bacteremia in cats. to test if b. henselae dna can be recovered from the dental pulp of cats buried a year previously, we used pcr with primers for a sequence of the conserved groel to test 104 teeth from 11 cats. seven of the cats were found positive; canine teeth were more frequently positive than molar teeth. where pcr sequences could be determined, they were identical to those of b. henselae marseille (four cats), b. henselae houston (one cat) or similar to ... | 2004 | 15652295 |
| bartonella quintana in a 4000-year-old human tooth. | bacteria of the genus bartonella are transmitted by ectoparasites (lice, fleas, ticks) and have mammalian reservoirs in which they cause chronic, asymptomatic bacteremia. humans are the reservoir of b. quintana, the louse-borne agent of trench fever. we detected dna of b. quintana in the dental pulp of a person who died 4000 years ago. | 2005 | 15655785 |
| prospective studies of bartonella of rodents. part i. demographic and temporal patterns in population dynamics. | the temporal dynamics of bartonella infections in a rodent community were described by repeatedly capturing and sampling individual animals. among six rodent species, from which bartonellae were isolated, cotton rats (sigmodon hispidus) accounted for > 98% of the bacteremic animals. all cotton rats captured four or more times were bartonella-culture positive at least once. the lowest monthly prevalence of bartonella in cotton rats was in june (49%) and the highest was in october (95%). prevalenc ... | 2004 | 15671735 |
| prospective studies of bartonella of rodents. part ii. diverse infections in a single rodent community. | the genetic diversity of bartonella species within a small mammal community and in individual cotton rats (sigmodon hispidus) was examined by trapping, capturing, sampling, and releasing of marked animals over a 17-month interval. based on sequence analyses of the bartonella glta gene, amplicons separated into four genogroups (a, b, c, and pin) containing 11 variants. although the prevalence of bacteremia due to different genogroups/variants of bartonella was temporally variable, variants of gen ... | 2004 | 15671736 |
| semi-nested pcr detection of bartonella henselae in ixodes persulcatus ticks from western siberia, russia. | questing adult ixodes persulcatus ticks from western siberia, russia were tested for infections with bartonella spp. using seminested pcr assay with primers specific to the groel gene. the proportion of ticks infected with bartonella spp. was 44% in 2002 (n = 50) and 38% in 2003 (n = 50). nucleotide sequences of a portion of the pcr products corresponded to bartonella henselae species. | 2004 | 15671737 |
| bartonella henselae in african lion, south africa. | | 2004 | 15672532 |
| bartonella clarridgeiae and b. henselae in dogs, gabon. | | 2004 | 15672535 |
| [bartonellosis: emerging infection]. | the spectrum of bartonella infections in humans shows a constant increase. the number of bartonella species responsible of zoonoses has increased from one to 7 during the past ten years. in addition numerous orphan clinical manifestations are now associated to bartonella henselae infections. animals and particularly domestic cat are the main reservoirs of bartonella. cats are healthy carriers of b. henselae and b. clarridgeiae, and can be bacteremic for months to years. cat-to-cat transmission o ... | 2004 | 15673067 |
| a review of emerging flea-borne bacterial pathogens in new zealand. | recent studies have shown that rickettsia typhi, r. felis, bartonella henselae, and b. clarridgeiae occur in new zealand. to raise awareness of these emerging and re-emerging flea-borne bacterial pathogens among new zealand health workers, we review the clinical features, diagnosis, and treatment of infections, and the biology of the major flea vectors. | 2005 | 15682209 |
| [cat-scratch disease]. | | 2005 | 15695034 |
| bartonella vinsonii subsp. arupensis as an agent of blood culture-negative endocarditis in a human. | we report the case of a patient hospitalized with endocarditis. the etiological diagnosis of bartonella was suggested by detection of high titers of antibodies by immunofluorescence and western blotting. two different nested pcrs performed on sera identified bartonella vinsonii subsp. arupensis by sequencing. | 2005 | 15695714 |
| serological diagnosis of human babesiosis by igg enzyme-linked immunosorbent assay. | an enzyme-linked immunosorbent assay (elisa) for the detection of igg antibodies to babesia microti antigen was developed. b. microti antigens were harvested from experimentally infected hamster blood and used as a coating antigen. the sensitivity and specificity of the igg elisa relative to immunofluorescent antibody assay (ifa) testing was 95.5% and 94.1%, respectively. according to the receiver operating characteristic curve analysis, the area under the curve was 0.987. no cross-reactivity of ... | 2004 | 15696612 |
| [newly emerging infections: catscratch disease]. | | 2004 | 15700401 |
| emerging or re-emerging bacterial zoonotic diseases: bartonellosis, leptospirosis, lyme borreliosis, plague. | there are a whole series of emerging and re-emerging zoonotic diseases present in the northern hemisphere and the author describes four of them, namely, bartonellosis, leptospirosis, lyme borreliosis and plague. reasons for the emergence or re-emergence of such diseases are not clear, but factors such as human demographics, economic development and land use, international travel and commerce, and microbial adaptation, are thought to be involved. control of emerging and re-emerging diseases has b ... | 2004 | 15702720 |
| cat-scratch disease (ocular bartonellosis) presenting as bilateral recurrent iridocyclitis. | an otherwise healthy 9-year-old girl presented with bilateral recurrent anterior uveitis. thirteen months later, the diagnosis of cat-scratch disease (ocular bartonellosis) was suspected when neuroretinitis appeared. confirmation was based on serological test results positive for bartonella henselae. antibiotic treatment completely cured the disease, and there have been no further manifestations during a follow-up period of 6 years. | 2005 | 15714406 |
| bartonellosis: light and shadows in diagnostic and therapeutic issues. | cat-scratch disease involves a prolonged and/or complicated course, and lymph node drainage is usually required. culture and molecular techniques often yield negative results, but immunofluorescence assays may give early information, and elevated antibodies may persist for months. cat-scratch disease should be suspected in patients with prominent swelling of lymph nodes draining from the upper limbs, limited systemic involvement, and typical epidemiological-clinical features. the temporal antibo ... | 2005 | 15715712 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 5-2005. a 53-year-old man with depression and sudden shortness of breath. | | 2005 | 15716566 |
| activation of hypoxia-inducible factor-1 in bacillary angiomatosis: evidence for a role of hypoxia-inducible factor-1 in bacterial infections. | bartonella species are the only known bacterial pathogens causing vasculoproliferative disorders in humans (bacillary angiomatosis [ba]). cellular and bacterial pathogenetic mechanisms underlying the induction of ba are largely unknown. | 2005 | 15723970 |
| crusted plaques in an immunocompromised host. | | 2005 | 15724025 |
| [erythema nodosum and adenopathy in a 15-year-old boy: uncommon signs of cat scratch disease]. | erythema nodosum rarely occurs in childhood and can be caused by cat scratch disease, as a result of agent bartonella henselae. we report the case of a teenager who presented erythema nodosum and bilateral inguinal adenitis. cat scratch disease diagnosis was confirmed by anti-bartonella henselae serologies. despite an appropriate antibiotic therapy, evolution was unfavourable with adenitis abcédation requiring surgical drainage. conclusion: erythema nodosum in children must let think to cat scra ... | 2005 | 15734128 |
| cat-scratch disease: otolaryngologic manifestations and management. | the bacteria bartonella henselae has been known as the principal causative agent of cat-scratch disease (csd) since 1992. it is an important cause of infectious lymphadenopathies in the head and neck. nevertheless, csd often remains unrecognized in cases of cervicofacial lymph node enlargement. | 2005 | 15746844 |
| potential limitations of the 16s-23s rrna intergenic region for molecular detection of bartonella species. | pcr targeting the 16s-23s rrna gene intergenic transcribed spacer (its) region has been proposed as a rapid and reliable method for the detection of bartonella species dna in clinical samples. because of variation in its sequences among bartonella species, a single pcr amplification can be used to detect different species within this genus. therefore, by targeting the its region, multiple pcrs or additional sample-processing steps beyond the primary amplification can be avoided when attempting t ... | 2005 | 15750079 |
| bacterial zoonoses and infective endocarditis, algeria. | blood culture-negative endocarditis is common in algeria. we describe the etiology of infective endocarditis in this country. samples from 110 cases in 108 patients were collected in algiers. blood cultures were performed in algeria. serologic and molecular analysis of valves was performed in france. infective endocarditis was classified as definite in 77 cases and possible in 33. causative agents were detected by blood cultures in 48 cases. all 62 blood culture-negative endocarditis cases were ... | 2005 | 15752438 |
| impact of a molecular approach to improve the microbiological diagnosis of infective heart valve endocarditis. | even today, infective endocarditis (ie) remains a severe and potentially fatal disease demanding sophisticated diagnostic strategies for detection of the causative microorganisms. despite the use of appropriate laboratory techniques, classic microbiological diagnostics are characterized by a high rate of negative results. | 2005 | 15753218 |
| a review of bacterial pathogens in ctenocephalides felis in new zealand. | the cat flea, ctenocephalides felis, is the recognised vector of bartonella henselae, b. clarridgeiae and rickettsia felis. although these gram-negative bacteria were only described in the last decade, they are already known to cause a variety of diseases in people, particularly children and the immunosuppressed. such diseases include cat-scratch disease, bacillary angiomatosis, endocarditis, bacteraemia, encephalopathy, neuroretinitis, osteomyelitis and peliosis hepatis. although most infection ... | 2004 | 15768135 |
| [study on the prevalence of bartonella species in rodent hosts from different environmental areas in yunnan]. | to investigate bartonella infections in small mammalian reservoir hosts from different environments and types of climate in yunnan. | 2004 | 15769319 |
| [bartonella and bartonellosis--emerging and re-emerging infections: epidemiology, clinical course, diagnosis]. | information on the epidemiology, clinic and diagnostics of bartonellosis is updated. the importance of bartonellosis lies in the fact that its main risk group embraces patients with immunodeficiencies of different origin, the number of such patients constantly growing. the diagnostics of bartonellosis is insufficiently developed and the research on bartonella organisms, except for the trunch (volynia) fever causative agent, is insufficient in our country. | 2005 | 15773411 |
| [non infectious endocarditis: retrospective study (6 cases)]. | if there is cardiac valve vegetation and the blood cultures are negatives we need to look for slow growing bacteria, fungi, legionella pneumophilia, bartonella henselae and quintana, brucella melitensis and abortus, coxiella burneti, chlamydiae pneumoniae by serologic tests. the diagnosis of non- infectious endocarditis could be considered only if these results were negative. the main purpose of this study was to describe the clinical and echocardiographic signs of non-infectious endocarditis ca ... | 2005 | 15777581 |
| [bartonella hensalae encephalopathy]. | bartonella hensalae is a poorly known cause of encephalopathy in young subjects. | 2005 | 15798550 |
| bartonelosis (carrion's disease) in the pediatric population of peru: an overview and update. | bartonellosis, or carrion's disease, is an endemic and reemerging disease in peru and ecuador. carrion's disease constitutes a health problem in peru because its epidemiology has been changing, and it is affecting new areas between the highland and the jungle. during the latest outbreaks, and previously in endemic areas, the pediatric population has been the most commonly affected. in the pediatric population, the acute phase symptoms are fever, anorexia, malaise, nausea and/or vomiting. the mai ... | 2004 | 15798808 |
| detection of the bartonella henselae gene sequence in lymph nodes of children with kikuchi's disease. | | 2005 | 15805408 |
| bartonella seropositivity in children with henoch-schonlein purpura. | an association between henoch-schonlein purpura (hsp) and seropositivity for bartonella henselae (bh) has been described. the objective of this study was to see if such an association exists in northern alberta. | 2005 | 15807903 |
| prevalence of bartonella henselae in cats in catalonia, spain. | bartonella henselae, an emerging pathogen bacterium, is the main causative agent of the cat scratch disease. while the first clinical descriptions were associated with immunosupressed patients, it is now more frequently observed in patients with normal immune status (endocarditis and bacteremia). cats were found to be the only known reservoir of b. henselae. in this paper, we report the results obtained in the first study made to investigate the prevalence of b. henselae bacteremia and antibodie ... | 2005 | 15827285 |
| factors associated with the rapid emergence of zoonotic bartonella infections. | within the last 15 years, several bacteria of the genus bartonella were recognized as zoonotic agents in humans and isolated from various mammalian reservoirs. based on either isolation of the bacterium or pcr testing, eight bartonella species or subspecies have been recognized as zoonotic agents, including b. henselae, b. elizabethae, b. grahamii, b. vinsonii subsp. arupensis, b. vinsonii subsp. berkhoffii, b. grahamii, b. washoensis and more recently b. koehlerae. the present manuscript review ... | 2005 | 15845231 |
| the bartonella vinsonii subsp. arupensis immunodominant surface antigen brpa gene, encoding a 382-kilodalton protein composed of repetitive sequences, is a member of a multigene family conserved among bartonella species. | bartonella proteins that elicit an antibody response during an infection are poorly defined; therefore, to characterize antigens recognized by the host, a bartonella genomic expression library was screened with serum from an infected mouse. this process led to the discovery of a bartonella vinsonii subsp. arupensis gene encoding a 382-kda protein, part of a gene family encoding large proteins, each containing multiple regions of repetitive segments. the genes were termed brpa to -c (bartonella r ... | 2005 | 15845521 |
| infection of human cd34+ progenitor cells with bartonella henselae results in intraerythrocytic presence of b. henselae. | although there is evidence that endothelial cells are important targets for human pathogenic bartonella species, the primary niche of infection is unknown. here we elucidated whether human cd34+ hematopoietic progenitor cells (hpcs) internalize b. henselae and may serve as a potential niche of the pathogen. we showed that b. henselae does not adhere to or invade human erythrocytes. in contrast, b. henselae invades and persists in hpcs as shown by gentamicin protection assays, confocal laser scan ... | 2005 | 15860668 |
| bartonella species as a potential cause of epistaxis in dogs. | infection with a bartonella species was implicated in three cases of epistaxis in dogs, based upon isolation, serology, or pcr amplification. these cases, in conjunction with previously published reports, support a potential role for bartonella spp. as a cause of epistaxis in dogs and potentially in other animals, including humans. | 2005 | 15872304 |
| pathology of bartonella endocarditis in six dogs. | in a 5-year retrospective study of dogs presenting to the veterinary medical teaching hospital at the university of california, davis, there were 31 histologic diagnoses of valvular endocarditis. by polymerase chain reaction (pcr) amplification of embedded valvular tissue, bartonella organisms were exclusively associated with 6 out of 31 cases (19%). confirmed bartonella cases involved the aortic valve alone (five out of six) or in combination with the mitral valve (one of six). microscopic feat ... | 2005 | 15872387 |
| [new etiologies responsible for infective endocarditis with negative blood cultures]. | the prevalence of infective endocarditis with negative blood cultures varies in the different series from 5 to 25%. there are certain explanations of negative blood culture endocarditis: previous incorrect antibiotic therapy before obtaining blood samples (antibiotic treatment inhibits the growth of germs, and therefore bacteremia, without sterilizing the vegetations); infective endocarditis due to fastidious microorganism, that is of difficult cultivation and identification; infective endocardi ... | 2005 | 15875498 |
| multifocal bone marrow involvement in cat-scratch disease. | we describe 2 children with prolonged fever of unknown origin and prominent skeletal pain who had multifocal bone disease caused by bartonella infection. initial radiologic studies, including plain films, radionuclide scintigraphy and computed tomography, yielded negative results. in both cases, magnetic resonance imaging revealed multiple enhancing bone marrow lesions consistent with clinical symptoms. microbiologic diagnoses were established serologically. | 2005 | 15876956 |
| blood culture-negative endocarditis in a reference center: etiologic diagnosis of 348 cases. | to identify the current etiologies of blood culture-negative infective endocarditis and to describe the epidemiologic, clinical, laboratory, and echocardiographic characteristics associated with each etiology, as well as with unexplained cases, we tested samples from 348 patients suspected of having blood culture-negative infective endocarditis in our diagnostic center, the french national reference center for rickettsial diseases, between 1983 and 2001. serology tests for coxiella burnettii, ba ... | 2005 | 15879906 |
| high prevalence of bartonella quintana endocarditis in sfax, tunisia. | bartonella quintana is a fastidious microorganism associated with blood culture negative endocarditis. in this study, 40 sera with cross-reactivity between chlamydia species from patients from sfax, tunisia, were serologically tested for bartonella. thirteen sera were positive for bartonella with igg titers >/=1:800. western blot and cross-absorption confirmed the diagnosis of bartonella quintana endocarditis in 12 cases and bartonella henselae endocarditis in 1 case. these sera were also positi ... | 2005 | 15891120 |
| autochthonous epidemic typhus associated with bartonella quintana bacteremia in a homeless person. | trench fever, a louse-borne disease caused by bartonella quintana, is reemerging in homeless persons. epidemic typhus is another life-threatening louse-borne disease caused by rickettsia prowazekii and known to occur in conditions of war, famine, refugee camps, cold weather, poverty, or lapses in public health. we report the first case of seroconversion to r. prowazekii in a homeless person of marseilles, france. this was associated with b. quintana bacteremia. although no outbreaks of typhus ha ... | 2005 | 15891141 |
| [diseases produced by bartonella]. | the genus bartonella is cause of a broad number of emerging and re-emerging infectious diseases. clinical manifestations depend on the implicated bartonella sp. and the immunity of the host. because there is not a universal therapy for this infection, treatment should be chosen individually. bartonella sp. is responsible of potentially serious clinical pictures (endocarditis, chronic bacteremia, bacillary angiomatosis, carrion's disease, etc.), so clinical suspicion, a quick diagnosis and an ear ... | 2005 | 15899181 |
| seroprevalence of antibodies against bartonella species and evaluation of risk factors and clinical signs associated with seropositivity in dogs. | to determine the seroprevalence of antibodies against bartonella spp in a population of sick dogs from northern california and identify potential risk factors and clinical signs associated with seropositivity. | 2005 | 15900951 |
| [lice and lice-borne diseases in humans]. | among the three lice which parasite the human being, the human body louse, pediculus humanus humanus, is a vector of infectious diseases. it lives and multiplies in clothes and human infestation is associated with cold weather and a lack of hygiene. three pathogenic bacteria are transmitted by the body louse: 1) rickettsia prowazekii, the agent of epidemic typhus of which the most recent outbreak (and the largest since world war ii) was observed during the civil war in burundi; 2) borrelia recur ... | 2005 | 15903070 |
| case 5-2005: a man with depression and shortness of breath. | | 2005 | 15917395 |
| lyme disease: point/counterpoint. | lyme disease represents a growing public health threat. the controversial science and politics of lyme disease have created barriers to reliable diagnosis and effective treatment of this protean illness. two major clinical hurdles are the absence of a therapeutic end point in treating borrelia burgdorferi, the spirochetal agent of lyme disease, and the presence of tickborne coinfections with organisms such as babesia, anaplasma, ehrlichia and bartonella that may complicate the course of the dise ... | 2005 | 15918774 |
| virulence-associated type iv secretion systems of bartonella. | type iv secretion systems (t4sss) are transport machineries of gram-negative bacteria that mediate interbacterial dna-transfer, and secretion of virulence factors into eukaryotic target cells. a growing number of human pathogenic bacteria use t4sss for intercellular delivery of effector molecules that modify host cellular functions in favour of the pathogen. recent advances in studying the molecular mechanisms of bartonella pathogenesis have provided evidence for the central roles of two distinc ... | 2005 | 15935675 |
| cat scratch disease: an unusual cause of facial palsy and partial ptosis: case report. | | 2005 | 15944991 |
| a man with chest pain and glomerulonephritis. | | 2005 | 15950721 |
| unusual trafficking pattern of bartonella henselae -containing vacuoles in macrophages and endothelial cells. | bartonella henselae, the agent of cat-scratch disease and vasculoproliferative disorders in humans, is a fastidious facultative intracellular pathogen, whose interaction with macrophages and endothelial cells (ecs) is crucial in the pathogenesis of these diseases. however, little is known about the subcellular compartment in which b. henselae resides. two hours after infection of murine macrophages and human ecs, the majority of b. henselae-containing vacuoles (bcvs) lack typical endocytic marke ... | 2005 | 15953033 |
| evasion of toll-like receptor 5 by flagellated bacteria. | toll-like receptor 5 (tlr5) recognizes an evolutionarily conserved site on bacterial flagellin that is required for flagellar filament assembly and motility. the alpha and epsilon proteobacteria, including the important human pathogens campylobacter jejuni, helicobacter pylori, and bartonella bacilliformis, require flagellar motility to efficiently infect mammalian hosts. in this study, we demonstrate that these bacteria make flagellin molecules that are not recognized by tlr5. we map the site r ... | 2005 | 15956202 |
| novel chemically modified liquid medium that will support the growth of seven bartonella species. | bacteria of the genus bartonella, a member of the alphaproteobacteria, are fastidious, gram-negative, aerobic bacilli that comprise numerous species, subspecies, and subtypes. in human and veterinary medicine, species isolation remains a vital component of the diagnostic and therapeutic management of bartonella infection. we describe a novel, chemically modified, insect-based liquid culture medium that supports the growth of at least seven bartonella species. this medium will also support cocult ... | 2005 | 15956379 |
| signature proteins that are distinctive of alpha proteobacteria. | the alpha (alpha) proteobacteria, a very large and diverse group, are presently characterized solely on the basis of 16s rrna trees, with no known molecular characteristic that is unique to this group. the genomes of three alpha-proteobacteria, rickettsia prowazekii (rp), caulobacter crescentus (cc) and bartonella quintana (bq), were analyzed in order to search for proteins that are unique to this group. | 2005 | 15960851 |
| detection of rickettsia, borrelia, and bartonella in carios kelleyi (acari: argasidae). | carios kelleyi (colley & kohls 1941), a tick associated with bats and bat habitats, has been reported to feed on humans, but there is little published data regarding the presence of vector-borne pathogens in these ticks. c. kelleyi nymphs and adults were collected from residential and community buildings in jackson county, iowa, and tested by polymerase chain reaction for rickettsia, borrelia, bartonella, coxiella, and anaplasma. rickettsia dna was detected in 28 of 31 live ticks. sequences of t ... | 2005 | 15962801 |
| identification, cloning, and expression of the camp-like factor autotransporter gene (cfa) of bartonella henselae. | the camp reaction was first described by christie et al. (r. christie, n. e. atkins, and e. munch-petersen, aust. j. exp. biol. 22:197-200, 1944) as the synergistic lysis of sheep red blood cells by staphylococcus aureus sphingomyelinase and camp factor (cohemolysin), a secreted protein from group b streptococci. we observed a camp-like reaction when bartonella henselae was grown in close proximity to s. aureus on 5% sheep blood agar. this study describes the cloning, sequencing, and characteriz ... | 2005 | 15972511 |
| disruption of a host-parasite system following the introduction of an exotic host species. | the potential of biological invasions to threaten native ecosystems is well recognized. here we describe how an introduced species impacts on native host-parasite dynamics by acting as an alternative host. by sampling sites across an invasion front in ireland, we quantified the influence of the introduced bank vole (clethrionomys glareolus) on the epidemiology of infections caused by flea-transmitted haemoparasites of the genus bartonella in native wood mice (apodemus sylvaticus). bartonella inf ... | 2005 | 15977903 |
| [bartonellosis and a possible role of ixodes ticks (family ixodidae, order parasitiformes) in the transmission of pathogenic bartonella bacteria]. | the papers reviews the literature on bartonellosis and a role of ixodes ticks, including the representatives of the genus ixodes, in the circulation and transmission of bartonella bacteria. it shows that man can be infected with pathogenic bartonella bacteria by the bite of ticks. the paper also presents data on tick-transmitted human and animal mixed infections, including bartonellosis. | 2005 | 15984622 |
| environmental factors associated with bartonella vinsonii subsp. berkhoffii seropositivity in free-ranging coyotes from northern california. | bartonella vinsonii subsp. berkhoffii is a newly recognized pathogen of domestic dogs and humans. coyotes (canis latrans) are considered an important reservoir of this bacterium in the western united states, but its vectors are still unknown. our objective was to identify environmental factors associated with bartonella antibody prevalence in 239 coyotes from northern california, using an enzyme-linked immunosorbent assay. in addition, associations were evaluated between b. v. berkhoffii and two ... | 2005 | 16011426 |
| persistent abdominal pain. | | 2005 | 16015406 |
| survey of tickborne infections in denmark. | we conducted a study of the distribution and prevalence of tickborne infections in denmark by using roe deer as sentinels. blood samples from 237 roe deer were collected during the 2002-2003 hunting season. overall, 36.6% of deer were borrelia seropositive, while 95.6% were anaplasma phagocytophilum positive; all animals were negative for bartonella quintana and b. henselae by indirect immunofluorescence assay. when a hemagglutination-inhibition test was used, 8.7% of deer were found positive fo ... | 2005 | 16022780 |
| [carrión disease: two centuries later]. | | 2005 | 16022842 |
| bartonella henselae bacteraemia in domestic cats from auckland. | bartonella henselae causes most cases of cat scratch disease, a self-limited localised lymphadenopathy illness of humans. bartonella henselae also causes disseminated cutaneous and visceral disease in immunocompromised people. cat blood (1-5 ml) collected from cats in the auckland area was processed and plated on to 5% sheep blood brain heart infusion agar and incubated at 35 degrees c in 5% co2 for 14 days. bartonella henselae was identified by colony morphology, gram's stain, twitching motilit ... | 1997 | 16031983 |
| bartonella henselae and domestic cats, jamaica. | | 2005 | 16032793 |
| macular hole in cat scratch disease. | to report the development of a macular hole as a complication of cat scratch disease. | 2005 | 16038666 |
| a 16-year-old adolescent boy with unilateral cervical lymphadenopathy suspicious for malignancy. | | 2005 | 16048405 |
| rapid identification of bartonella henselae by real-time polymerase chain reaction in a patient with cat scratch disease. | we report a localized submandibular lymph node infection in a patient with cat scratch disease. directly performing real-time polymerase chain reaction assay on the biopsy sample, bartonella henselae dna was simultaneously detected and identified. | 2005 | 16054323 |
| bartonella-host-cell interactions and vascular tumour formation. | bartonellae are arthropod-borne bacterial pathogens that typically cause persistent infection of erythrocytes and endothelial cells in their mammalian hosts. in human infection, these host-cell interactions result in a broad range of clinical manifestations. most remarkably, bartonellae can trigger massive proliferation of endothelial cells, leading to vascular tumour formation. the recent availability of infection models and bacterial molecular genetic techniques has fostered research on the pa ... | 2005 | 16064054 |
| bartonella species-induced prosthetic valve endocarditis associated with rapid progression of valvular stenosis. | | 2005 | 16077432 |
| experimental infection of white-tailed deer with anaplasma phagocytophilum, etiologic agent of human granulocytic anaplasmosis. | serologic and molecular evidence of anaplasma phagocytophilum has been demonstrated in white-tailed deer (wtd; odocoileus virginianus), and deer are an important host for the tick vector ixodes scapularis. in this study, we describe experimental infection of wtd with a. phagocytophilum. we inoculated four wtd with a human isolate of a. phagocytophilum propagated in tick cells. two additional deer served as negative controls. all inoculated deer developed antibodies (titers, > or =64) to a. phago ... | 2005 | 16081884 |
| diagnosis of cat scratch disease with detection of bartonella henselae by pcr: a study of patients with lymph node enlargement. | cat scratch disease (csd) is mostly due to bartonella henselae after inoculation of the organism through a skin injury. since the causative bacteria cannot be easily cultured from human lymph node samples, the diagnosis usually relies on epidemiological, clinical, histological, and serological criteria (classical criteria). a study was performed to determine the diagnostic value of pcr analysis for the detection of b. henselae for the diagnosis of csd and its place in the diagnostic strategy alo ... | 2005 | 16081914 |
| epidemiology of cat-scratch disease hospitalizations among children in the united states. | cat-scratch disease (csd), caused by infection with bartonella henselae, affects both children and adults but is principally a pediatric disease. typical csd is generally benign and self-limited and is characterized by regional lymphadenopathy with fever. infections can, however, be accompanied by focal or diffuse inflammatory responses (atypical csd) involving neurologic, organ (liver/spleen), lymphatic or skeletal systems. | 2005 | 16094224 |
| a nested-pcr with an internal amplification control for the detection and differentiation of bartonella henselae and b. clarridgeiae: an examination of cats in trinidad. | bartonella species are bacterial blood parasites of animals capable of causing disease in both animals and man. cat-scratch disease (csd) in humans is caused mainly by bartonella henselae and is acquired from the cat, which serves as a reservoir for the bacteria. a second species, b. clarridgeiae is also implicated in the disease. diagnosis of bartonellosis by culture requires a week or more of incubation on enriched media containing blood, and recovery is often complicated by faster growing con ... | 2005 | 16098227 |
| tyrosine-phosphorylated bacterial effector proteins: the enemies within. | the tyrosine phosphorylation of proteins has a central role during signal transduction in eukaryotes. recent progress shows that tyrosine phosphorylation is also a common feature of several effector proteins translocated by bacterial type iii and type iv secretion systems. the involvement of these secretion systems in disease development is exemplified by a variety of pathogenic processes: pedestal formation (tir of epec and citrobacter), cell scattering (caga of helicobacter), invasion (tarp of ... | 2005 | 16099656 |
| genome reduction in the alpha-proteobacteria. | more than 20 alpha-proteobacterial genomes are currently available. these range in size from 1-9 mb and represent excellent model systems for evolutionary studies of the organizational features of bacterial genomes. computational inferences have shown that genome reductions have occurred independently in lineages such as rickettsia and bartonella that are associated with intracellular lifestyles. analyses of these reduced genomes have provided insights into the evolution of vector-borne transmis ... | 2005 | 16099701 |
| abstracts for the 4th international conference on bartonella as emerging pathogens, 26-28 august 2005, uppsala, sweden. | | 2005 | 16100842 |
| bartonella quintana in domestic cat. | we recovered bartonella quintana dna from dental pulp of a domestic cat. this study, the first to detect b. quintana in a nonhuman mammal, changes our understanding of the epidemiology of this infection and proposes that cats may be an emerging source of human infection. | 2005 | 16102321 |