| in vivo and in vitro characterization of virulence-deficient mutants of vibrio cholerae. | in vitro and in vivo interactions between vibrio cholerae and the infant mouse intestinal environment were examined by using a number of virulence-deficient mutants of strain ca401 which are unable to induce a typical diarrheal response. in vitro interactions with upper bowel sections were evaluated by determining percent association of radiolabeled organisms with sections. in vivo behavior was evaluated in the upper bowel early in infection with radiolabeled inocula. ths relative degree of mech ... | 1979 | 457267 |
| [cholera today]. | | 1979 | 463105 |
| immunological characteristics of neo-antigens on the cell surface after neuraminidase treatment. | | 1979 | 463643 |
| approaches to effective tumor immunotherapy with cells and the enzyme neuraminidase. | | 1979 | 463670 |
| cholera in the gilbert island. i. epidemiological features. | an explosive epidemic of cholera due to vibrio cholerae, biotype el tor, serotype inaba, was centered on the coral atoll of tarawa, gilbert islands. this outbreak was a unique experience in the south and central pacific region. the principal mode of spread during the peak of the outbreak was probably through contamination of the main water supply. tarawa lagoon water and shellfish were found to be contaminated with v. cholerae and ingestion of raw fish and shellfish from the lagoon also served a ... | 1979 | 464187 |
| cholera in the gilbert islands. ii. clinical and laboratory findings. | an epidemic of cholera due to vibrio cholerae biotype el tor occurred in 1977 on tarawa in the gilbert islands. no cholera epidemic had occurred there previously and special problems were encountered in both the diagnosis and clinical management. the clinical features of the 585 hospital admissions on tarawa during the first 64 days of the epidemic were recorded. eight hospital deaths occurred in this period. a marked increase in cholera among malnourished gilbertese children was noted. simplifi ... | 1979 | 464188 |
| fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-alpha-d-n-acetylneuraminate) substrate. | | 1979 | 464297 |
| [pathways of enzymatic inactivation of levomycetin in el tor vibrios with plasmid and chromosome resistance to the antibiotic]. | two possible mechanisms of enzymatic inactivation of levomycetin, i.e. acetylation of oh-groups and reduction of the n-nitrophenylic component by the cells and cell-free extracts of v. eltor 2044 with the plasmid or chromosome types of antibiotic resistance were studied in vitro. the vibrio containing the extrachromosome determinants were resistant to a number of antibiotics. the rate of levomycetin acetylation by them under conditions of intensive aeration and reduction of the antibiotic aromat ... | 1979 | 464559 |
| [localization and activity of the neuraminidase in cholera vibrios]. | | 1979 | 465611 |
| monomer-micelle transition of the ganglioside gm1 and the hydrolysis by clostridium perfringens neuraminidase. | the action of clostridium perfringens neuraminidase on the ganglioside gm1 tritiated in the ceramide moiety was studied. the rates of hydrolysis of the gm1 ganglioside were determined from radioactivity in the neutral glycolipid product, which was separated from the substrate on deae-sephadex columns. in order to study the physical state of the substrate in the conditions used in the neuraminidase treatment, the critical micelle concentrations of the gm1 ganglioside were determined using formati ... | 1979 | 467431 |
| inhibition of growth of rat yoshida sarcoma using a neuraminidase treated tumour vaccine. | | 1979 | 468316 |
| antigenic changes in vibrio cholerae biotype eltor serotype ogawa after bacteriophage infection. | vibrio cholerae biotype eltor serotype ogawa cultures infected with temperate bacteriophage from lysogens of biotype eltor serotype hikojima yielded types with altered agglutination reactions. | 1979 | 468386 |
| [role of adsorption in microbial colonization of volcanic deposits]. | | 1979 | 470637 |
| the neuraminidase-induced enhanced immune response can be attributed to immune stimulatory and antigenic properties of the enzyme. | | 1979 | 473363 |
| [use of the a-2 elective medium for the differentiation of aeromonas from related microorganisms]. | the trial of culture medium a-2, proposed for the identification of aeromonas on the basis of the nutritional utilization of gelatin as the only source of nitrogen and starch as the source of carbon in view of the limited content of mineral components in the medium, revealed that no other species of the family vibronaceae grew in this medium, and it could be used in an additional test for the differentiation of vibrios from aeromonas. a group of strains isolated from human feces, surface water a ... | 1979 | 474006 |
| effect of particle size on lead absorption from the gut. | the relationship between particle size and absorption of lead particles from the gastrointestinal tract of the rat has been investigated. preparations of metallic lead of particle size between 0 and 250 micron were incorporated in laboratory rat diets and absorption determined by measurement of tissue lead concentrations attined under standard conditions. an inverse relationship was found between particle size and lead absorption; this relationship was most marked in the 0 to 100 micron range. a ... | 1979 | 475473 |
| a comparison of methods for measuring intestinal antibodies against vibrio cholerae in mice. | a re-evaluation was made of the efficiency with which some of the commonly used assays would detect intestinal antibodies. the data indicate that the most sensitive assays for the detection of intestinal antibodies are the baby mouse protection test and the radioimmunoassay. the reasons for the lack of sensitivity with other assay methods are discussed. | 1979 | 475670 |
| intestinal antibody to vibrio cholerae in immunised mice. | the immune response of the mouse to priming and booster doses of v. cholerae was studied to establish whether serum antibody could be used as a correlate of local immunity. serum antibody titres following oral boosting of orally-primed animals were shown to reflect the state of local intestinal immunity. this was not the case when the same oral booster dose was given to parenterally-primed animals. these results were discussed in relation to the human endemic situation. the highest titres of int ... | 1979 | 475671 |
| experimental occlusion of two small coronary arteries in the same heart. a new validation method for infarct size manipulation. | a method for the evaluation of interventions aimed at manipulation of infarct size is described. this method has 2 advantages over other methods: 1. two small-to-medium sized coronary branches of the same heart are occluded and reperfused in sequence. thereby a "control-infarct" can be compared with a "test-infarct", both within the same heart. 2. the amount of infarcted tissue in both areas is quantitated by using the p-nbt method. a condition of the method is that the areas of perfusion of bot ... | 1979 | 475727 |
| structural investigations of the lipopolysaccharide isolated from vibrio cholera, inaba 569 b. | on hydrolysis, the purified lipopolysaccharide (lps) isolated from vibrio cholera, inaba 569 b, yielded glucose, mannose, a heptose behaving like d-glycero-l-manno-heptose and one behaving like d-glycero-l-gluco-heptose, 2-amino-2-deoxyglucose, and glucuronic acid in the molar ratios of approximately 9:4:5:1:2:5. studies on the lps, the polysaccharide (ps), and carboxyl-reduced lps showed that the ps has a branched structure, with (1 leads to 2)-linked mannopyranosyl and a heptopyranosyl, and (1 ... | 1979 | 476718 |
| flagella-induced immunity against experimental cholera in adult rabbits. | the adult rabbit ligated ileal loop model was used to evaluate the prophylactic potential of a crude flagellar (cf) vaccine produced from the classical. inaba strain ca401. a greater than 1,000-fold increase in the challenge inoculum was required to induce an intestinal fluid response in actively immunized adult rabbits equivalent to that produced in unimmunized animals. similar protection was afforded against challenge with classical and el tor biotypes of both inaba and ogawa serotypes. highly ... | 1979 | 478635 |
| genetic mapping of toxin regulatory mutations in vibrio cholerae. | we have mapped a regulatory site mediating the hyperproduction of cholera toxin in mutants of vibrio cholerae strain 569b. mutations in this locus, called htx, result in the hypertoxinogenic phenotype, as measured by the ganglioside filter assay and immunoradial diffusion. transposon-facilitated recombination was used to construct improved genetic donors in 569b parental and hypertoxinogenic mutant strains. subsequent mapping by conjugation indicated that the htx locus was closely linked to the ... | 1979 | 479110 |
| purification of v. cholerae el tor hemolysin. | | 1979 | 483015 |
| the study of intestinal immunity against v. cholerae: purification of v. cholerae el tor haemagglutinin and the protective role of its antibody in experimental cholera. | v. cholerae el tor ogawa strain o17sr grown on trypticase soy agar were extracted with 0.05 m cyclohexylamino propane sulfonic acid (caps) ph 9.5 at 37 degrees c for 1 hour. the bacteria were then removed by centrifugation and millipore filtration. the filtered fluid, after being dialysed against many changes of cold distilled water, was concentrated and passed through sephadex g200 column. three protein profiles were eluted out with 0.05 m tris buffer ph 8.6. the haemagglutinin and the bacteria ... | 1979 | 483020 |
| adsorption and growth of vibrio cholerae on chitin. | incubation of vibrio cholerae of o-group serotype 1 with chitin particles resulted in adsorption of vibrios onto chitin; chitin-adsorbed v. cholerae survived exposure to acid better than nonadsorbed vibrios. v. cholerae multiplied in dialyzed chitin suspended in 4.2% nacl, suggesting that adherence to ingested chitin of crustacea might be of epidemiological significance by providing a substrate for vibrio multiplication as well as protection from gastric acid during stomach transit. | 1979 | 489131 |
| [several biological properties of the l-forms of cholera and nag vibrios]. | | 1979 | 494902 |
| leptazol antagonises the post-synaptic actions of gamma-aminobutyric acid [proceedings]. | | 1979 | 497563 |
| the effect of some anti-rheumatic agents on tuberculin pleurisy in the guinea-pig [proceedings]. | | 1979 | 497564 |
| [interaction between bdellovibrio bacteriovorus and cholera vibrios in sewage]. | | 1979 | 499847 |
| serotyping of non-cholera vibrios. | the serotyping system for non-cholera vibrios reported by us in 1965 has been re-evaluated and extended. results from serotyping 2,624 cultures are presented. these isolates were accumulated over a period of 20 years and came from clinical and environmental samples in many parts of the world. included is a discussion of the use of terms "vibrio cholerae" and "non-cholera vibrios" for clinical reports. | 1979 | 500799 |
| [vibrio cholerae carriers]. | | 1979 | 506155 |
| [oral chemical vaccine made from a toxigenic strain of v. cholerae, ogawa serovar (an experimental study)]. | | 1979 | 506602 |
| [hemolytic properties of el tor cholera vibrios]. | the hemolytic factor of vibrio cholerae, biotype eltor, is bound to the cellular structures and can be liberated into the environment. the inhibiting action of proteases on the hemolytic activity of vibrios suggests that the proteinaceous hemolysin component of these organisms plays an important role in the process of red blood cell lysis. the inhibition of the hemolytic activity of vibrios by ca2+ ions seems to be connected with the activation of intracellular phospholipases. | 1979 | 506605 |
| transfection of vibrio cholerae by bacteriophage phi 149 dna. | | 1979 | 508339 |
| synthesis of anomeric ethyl ketosides of 5-n-acetyl-d-neuraminic acid. | the syntheses of anomeric ethyl ketosides of 5-n-acetyl-d-neuraminic acid are described. the alpha-anomer prepared by a modified koenigs-knorr procedure starting from acetochloroneuraminic acid is quantitatively cleaved by vibrio cholerae neuraminidase. proton-catalyzed reaction of 5-n-acetyl-d-neuraminic acid with ethanol yields the beta-anomer. | 1979 | 511115 |
| some properties of a vibrio-cholerae bacteriophage phi 2. | | 1979 | 511226 |
| structure-function relationship: biological activities of the lipopolysaccharides and lipid a from vibrio cholerae. | the biological activities of lipopolysaccharides and the lipid a moiety from five different strains of vibrio cholerae have been investigated. lipid a was biologically the most active component of lipopolysaccharides from these bacteria. immunization of rabbits with lipid a from inaba (66/64) strain led to the production of specific antibodies to lipid a. on fractionation of the immunoglobulins with sephadex g-200 column chromatography, antibodies against lipid a were detected in the igm and igg ... | 1979 | 512418 |
| [the pharmacological profile of sts 557 (proceedings)]. | | 1979 | 515135 |
| 2,3,7,8-tetrachlorodibenzo-p-dioxin: covalent binding of reactive metabolic intermediates principally to protein in vitro. | 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) is metabolized by the mouse liver cytochrome p-450-mediated monooxygenase system to reactive intermediates which bind 'covalently' to cellular macromolecules. although very difficult to quantitate, the presumably covalent binding to microsomal protein occurs between 120 and 2,640 times more readily than binding to deproteinized dna in the in vitro reaction. because of the extremely high rate of binding to protein rather than to dna, it is visualized tha ... | 1979 | 515166 |
| [comparison of the multiplication of vibrio cholerae bacteria, proteus biotype, in a liquid nutrient medium under gamma irradiation and dilution of the cell suspensions]. | | 1979 | 515375 |
| microcephaly associated with kyphoscoliosis and cleft palate in a yankassa lamb. | | 1979 | 516302 |
| firing of horses. | | 1979 | 516355 |
| [assimilation of certain amino acids administered to animals of different ages]. | changes in the content of some amino acids (tryptophane, lysine, histidine and arginine) in blood plasma were studied in young and old rabbits administered lysine, arginine and urea into the stomach. a decrease in utilization rate of the test amino acids in old animals, their interdependence and the effect of urea administration on the lysine level in blood serum at a relatively stable content of tryptophane and histidine were established. a conclusion is drawn about the necessity of taking into ... | 1979 | 516594 |
| [response of certain laboratory animals to being fed an ocean fish, the ruvette]. | | 1979 | 516605 |
| [state of biochemical indices of rat blood erythrocytes following sunflower oil administration]. | | 1979 | 516606 |
| [dry adapting additive and its use in dairy products for approximating the composition of human milk]. | the paper concerns a procedure for a new product, dry adapting additive (daa), designed for manufacture of liquid substitutes of breast milk under industrial conditions. the chemical composition of adapted milk mixtures is compared to that of breast milk. procedures for adapted mixtures to be manufactured at city milk kitchens, food concentrate factories and under domestic conditions have been developed, with the mixtures being widely tried on clinical basis. | 1979 | 516610 |
| [functional state of the liver during acute exposure to fozalon and despirol]. | | 1979 | 516618 |
| [acetylcysteine treatment of acute poisoning with epichlorohydrin and its synthesis semiproducts]. | | 1979 | 516621 |
| [similarity of the dna mucleotide sequences of vibrios]. | the systematic position of some vibrio species was ascertained by the method of molecular dna -- dna hybridization. the dna of the brine vibrios v. costicola and v. fischeri were shown to have about 10% of sequences homologous with dna of a typical cholera vibrio (v. cholerae eltor no. 334). similarity between the genomes of other representatives of the vibrionaceae family, as well as in dna hybridization of v. costicola and v. fischeri, was found to be approximately on the same level. all speci ... | 1979 | 516958 |
| cyanide toxicity from the thermal degradation of rigid polyurethane foam. | thermal degradation products (tdp) from a model, rigid polyurethane foam were collected in such a manner as to eliminate carbon monoxide and other gases with low boiling points. the effects in rats resulting from intratracheal intubation (i.t.) of the tdp are discussed. cyanide was found to be a major factor associated with severe toxic responses of the experimental rats. | 1979 | 517435 |
| inhalation toxicity studies with 1,3-butadiene -- 2. 3 month toxicity study in rats. | the available toxicological data for 1,3-butadiene are limited and contradictory. three month toxicity and two year carcinogenicity studies have therefore been initiated to identify any potential hazard to occupationally exposed personnel. the results of the 3 month study are reported in this paper. five groups of sprague-dawley rats were exposed to 1,3-butadiene gas at atmospheric concentrations of 0, 1000, 2000, 4000 and 8000 ppm v/v respectively, 6 hours/day, 5 days/week for 13 weeks. forty m ... | 1979 | 517438 |
| [observations on vibrio cholerae nag infections]. | | 1979 | 518762 |
| orofacial tumours induced in rats with radioactive cerium chloride. | | 1979 | 518961 |
| influenza virus infection of mouse lymphoblasts alters the binding affinity of anti-h-2 antibody: requirement for viral neuraminidase. | | 1979 | 520406 |
| fer de lance virus (fdlv): a probable paramyxovirus isolated from a reptile. | a new virus has been isolated by inoculation of lung tissues of diseased snakes into snake embryos. homogenates of infected embryo tissues caused c.p.e. in cell cultures incubated at 30 degrees c. the virus replicates in a wide variety of reptilian or mammalian cell types incubated at 30 degrees c, inducing either syncytium formation or minimal or no cytopathic changes. efficient replication occurs in embryonated hens' eggs at 27 to 30 degrees c. the virus haemagglutinates guinea pig and chick e ... | 1979 | 521797 |
| the regulation of prolactin release by the anterior pituitary [proceedings]. | | 1979 | 521914 |
| clinical myiasis. | human clinical myiasis is a rare entity in temperate zones, but it is of frequent occurrence among indigenous populations in tropical countries. the physician in practice in temperate zones, especially in urban areas, will generally see cases in those who have returned from rural travel or duty tours in tropical countries.temperate zone physicians by training and clinical services frequently are not prepared to accurately diagnose and treat cases of myiasis. this paper is a report of experiences ... | 1979 | 522188 |
| experimental granulomatous inflammation: ii. effect of injection of intact and disrupted killed tubercle bacilli into freund adjuvant-sensitized cavies. | the reaction of freund adjuvant-immunized cavies to subsequent injection of mycobacterium tuberculosis h37ra is confirmed as an immunologically mediated phenomenon. ultrasonic disruption of mycobacteria to be injected as "challenge" markedly increases the intensity of the consequent 24-48 h reaction and subsequent fibrosis in freund adjuvant-sensitized cavies and has an apparently inhibiting effect on the extent of subsequent granuloma formation with marked reduction of the density of epithelioi ... | 1979 | 523183 |
| hepatitis b surface antigen and antibody status in biopsy proven chronic hepatitis in singapore. | during the period between january 1975 and august 1976, 203 liver biopsies were received at the singapore general hospital from patients with a variety of liver diseases. a histological diagnosis of chronic hepatitis was made in 29 patients: 13 cases of chronic aggressive hepatitis (c.a.h.). 10 cases chronic persistent hepatitis (c.p.h.) and 6 of chronic lobular hepatitis (c.l.h.). c.p.h. and c.l.h. were found mainly in the third and fourth decades. c.a.h. was more common in the fifth to seventh ... | 1979 | 523186 |
| response of the fetal and newborn lamb to glucose and tolbutamide infusions. | tolbutamide infused into the chronically catheterized sheep fetus produced significant secretion of insulin. an optimal dose range of 100-200 mg/kg estimated fetal weight was demonstrated. paired tolbutamide and glucose infusions using a square wave technique demonstrated that although early phase insulin secretion is dimished in the fetus, this is not due to an absolute deficiency of stored insulin. tolbutamide produced peak insulin concentrations of 51.6 +/- 9.0 muu/ml by 20 min postinfusion i ... | 1979 | 523198 |
| [experiments on the treatment of yoshida tumor with neuroaminidase of vibrio cholerae]. | | 1979 | 523718 |
| effect of prostaglandin f2 alpha on temperature and behaviour of centrally sympathectomized rats. | prostaglandin f2 alpha (pg f2 alpha) in doses of 1 and 10 micrograms applied intraventricularly causes a rise in body temperature and exerts a sedative action on rat behaviour. chemical sympathectomy of the central nervous system (cns) induced by a twofold intraventricular administration of 250 micrograms of 6-hydroxydopamine reduces the influence of pg f2 alpha on the body temperature and behaviour. reserpine administered to rats with chemical sympathectomy of the central nervous system reverse ... | 1979 | 525140 |
| anatomy of musculus levator veli palatini in the 15-week human fetus. | the morphology of musculus levator veli palatini in the 15-week fetus was analyzed using 30-micrometer subserial sections. the sample included 26 specimens, of which 9 each were sectioned coronally and sagittally while 8 were sectioned in the transverse plane. at this stage of development m. levator veli palatini takes a general attachment to the precursor of the petrous part of the temporal bone, and, in some cases, auxiliary attachments to the auditory tube complex were also observed. at its o ... | 1979 | 525252 |
| the relationship between early automatic and late voluntary compensatory responses to muscle stretch in the long flexor of the human thumb [proceedings]. | | 1979 | 529071 |
| effect of vibration on the mechanical resistance of the human forearm to small imposed sinusoidal movements [proceedings]. | | 1979 | 529079 |
| the effects of sudden airway hypercapnia on the initiation of exercise hyperpnoea in man. | 1. in three healthy individuals, the first breath of cycle ergometer exercise was characterized by increases of minute ventilation (ve) and pulmonary capillary co2 output (vco2), with little change of end-tidal pco2, suggesting a concomitant increase of pulmonary blood flow (q) and preservation of v/q status. functional residual capacity fell, depleting lung gas stores of o2 and co2. 2. the following hypothesis purporting to account for the initiation of exercise hyperpnoea was examined (filley, ... | 1979 | 529086 |
| time-course of changes in baroreflex sensitivity during the development of renovascular hypertension in rats [proceedings]. | | 1979 | 529094 |
| relationships between hair follicle afferent fibres and spinocervical tract neurones in the cat [proceedings]. | | 1979 | 529108 |
| [lodgement of the intraventricular catheter into cerebral parenchima in infantile hydrocephalus (author's transl)]. | ten cases of hydrocephalus of diverse ethiology, treated with ventriculo-peritoneal shunt are presented. in following controls it was observed that extreme of the catheter was located in cerebral parenchima. these features were followed of minimal clinics alterations and electroencephalographic focal manifestations. the pathogenesis of the complication due to the findings in the computerized axial tomography (cat) and the real value in the diagnosis of this complication are analized. | 1979 | 533055 |
| the suppressive effect of circulating specific antibody on the response to oral immunisation with vibrio cholerae. | species igg antibody given intravenously 3-4 hours prior to oral immunisation with vibrio cholerae led to a specific depression of both the systemic and loca limmune response. one vibriocidal unit of igg antibody, which itself would given undetectable levels of circulating specific antibody, was significantly immunosuppressive. the suppression is considered to be due to central repression of the antigen-reactive lymphocyte, rather than to antigen exclusion at the gut mucosal surface. the repress ... | 1979 | 533481 |
| clearance of bacteria from lungs of mice after opsonising with igg or iga. | the clearance of organisms from the lungs of mice was followed after aerosol administration. preopsonisation of the organisms with immune serum, as a source of specific antibody, enhanced the rate of pulmonary clearance while s.iga delayed clearance. in the peritoneal cavity, bacteria pre-treated with immune serum were cleared more rapidly than unopsonised bacteria, but s.iga had little effect. the presence of fc receptors for igg and not s.iga on alveolar macrophages suggests that, in secretion ... | 1979 | 533482 |
| persistence in the mouse gut as an important factor in oral immunogenicity of strains of v. cholerae. | the immune responses of mice following oral vaccination with two strains of live v. cholerae have been examined. a strain which persisted in the small intestine was a superior local immunogen by comparison with another non-persisting strain. local persistence and the ability to induce a local immune response appeared to be correlated, since the two vibrio strains elicited identical responses when given parenterally. | 1979 | 533484 |
| nucleic acid and protein metabolism in the pancreas, spleen, thymus, lung, cardiac and skeletal muscle and lens of undernourished female rats. | | 1979 | 533871 |
| mechanism of action of furazolidone: inter-strand cross-linking in dna & liquid holding recovery of vibrio cholerae cells. | | 1979 | 535918 |
| re-evaluation of antibacterial and antitoxin immunities in experimental cholera. | | 1979 | 535945 |
| study of an extensive outbreak of cholera in cooch behar during 1974. | | 1979 | 535968 |
| a mathematical model for the 1973 cholera epidemic in the european mediterranean region. | for the cholera epidemic that occurred in the european mediterranean region in the summer of 1973, a simple deterministic mathematic model is proposed; it consists of a system of two ordinary differential equations which concern the evolution of the human infective population in a town community and of bacteria population in the sea. it is conjectured that the infection process obeys a non linear saturation-type law. a phase space analysis is performed for the system of equations. conclusions ar ... | 1979 | 538301 |
| an evaluation of the bovine -- onchocerca gibsoni, onchocerca gutturosa model as a tertiary screen for drugs against onchocerca volvulus in man. | in this trial suramin, diethylcarbamazine, trichlorphon, levamisole, mebendazole, melarsonyl potassiu, hoechst 33258 and tinidazole were administered to cattle infected with o. gibsoni and o. gutturosa to determine the usefulness of this screen in predicting the effect of drugs in man against. o. volvulus except for melarsonyl potassium which was macrofilarticidal against o. gutturosa but not o. gibsoni when cattle were slaughtered 6 weeks after treatment. it was concluded that cattle infected w ... | 1979 | 538819 |
| absence of antiarrhythmic effects of helium in patients with spontaneous premature ventricular beats at rest. | six patients with spontaneously occurring arrhythmias were studied to assess the antiarrhythmic properties of helium. the patients were divided into two subgroups breathing air, helium-oxygen (heliox), and nitrogen-oxygen (nitrox) in an alternating sequence during successive 20-min periods under continuous ecg surveillance at rest. there were no significant reductions in spontaneously occurring premature ventricular beats while breathing heliox, compared to breathing air of nitrox. alternating t ... | 1979 | 538859 |
| vein grafts in microvascular surgery. | the judicious use of vein grafts will lessen the incidence of thrombosis in microvascular surgery and help to overcome problem of vessels loss. vein grafts are readily available and do not pose any major disadvantages. | 1979 | 539801 |
| identification of a new allele of es-i segregating in an inbred strain of mice. | a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation. | 1979 | 540008 |
| identification of a new allele of es-i segregating in an inbred strain of mice. | a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation. | 1979 | 540008 |
| in vitro interaction of furazolidone with dna: part i-photoinactivation of the cholera phage pl 163/10. | | 1979 | 540940 |
| effect of metal ions on end products of glucose fermentation by inaba serotypes of vibrio cholerae & vibrio eltor. | | 1979 | 540983 |
| studies on cholera carriers and their role in transmission of the infection: a preliminary report. | | 1979 | 541013 |
| lipopolysaccharide of vibrio cholerae. (iii) -chemical and serological study on r antigen-. | | 1979 | 541866 |
| effect of sodium hydroxide upon protein binding to filter paper disks and its significance in the determination of protein in colorimetric and radioisotopic assays. | | 1979 | 543545 |
| antigenicity of ehrlich ascites through neuraminidase treatment of cells. | | 1979 | 544474 |
| e1tor vibrio isolated in surat during 1973-75. | | 1979 | 544483 |
| vibrios in acute diarrhoea. | | 1979 | 544501 |
| [new pyridazine derivatives with physiological activity]. | | 1979 | 545610 |
| inheritance of malignancy in somatic cell hybrids. | after a recall of the importance of early basic developments of in vitro established cell lines for investigations on malignant transformation, a survey of essential steps in the study of malignancy by means of somatic cell hybridization is presented. since the early sixties, in vitro crosses of malignant versus nonmalignant parental cells have provided many experimental models in which mechanisms of expression of malignancy have been approached. allogenic as well as xenogenic cell matings resul ... | 1979 | 545728 |
| [pharmacokinetic study in the rat of a new hypoglycemic agent: glisolamide]. | | 1979 | 546671 |
| synergistic protection against experimental cholera by immunization with cholera toxoid and vaccine. | rabbits were immunized with two parenteral injections of wellcome toxoid px389a, wyeth toxoid 20101, or merck bivalent vaccine. other groups of rabbits were immunized with combinations of the merck vaccine and each of the two toxoids. antitoxin responses were monitored in each group of rabbits before livecell challenge of each animal by the ligated intestinal loop assay. inaba and ogawa strains of vibrio cholerae were used for challenge experiments. basically, the data indicate that the toxoids ... | 1979 | 546785 |
| protection against experimental cholera by oral or parenteral immunization. | comparisons were made between the antigenic potency and protective capacity of several cholera toxin derivatives. rabbits were immunized parenterally with 50 microgram of cholera toxin, a subunit, b subunit, procholeragenoid, or wyeth glutaraldehyde toxoid 20101. examination of the antibody response curves revealed that cholera toxin elicited serum antitoxin responses that rose more quickly than in the subunit-immunized animals; however, antitoxin levels were of the same magnitude after 10 weeks ... | 1979 | 546789 |
| "in situ" variation of folic acid and dihydrofolate reductase in the caudate nucleus in the ageing process. | in bovine caudate nucleus of young animal, a folic acid-positive reaction was found in the perikarya and in the neuroglia in parallel with a high dihydrofolate reductase activity in the nerve cells. in old animals, folic acid increased in neurons, neuroglia and some nerve cell processes; the folate enzyme was markedly decreased in neurons and increased neuroglia nadh2-cytochrom-c-reductase activity was strongly positive in nerve cells in young and old animals. | 1979 | 546986 |
| [microclimate parameter study in a building for the cage battery raising of small pigs]. | an experiment was carried out in a reconstructed building for cell-battery rearing of young pigs, heated by two petroleum calorifers. six to eight pigs were placed in a cell in 4 row-cell batteries at two storeys. ventilation was realized by sucking ventilators, situated along the ridge of the building. temperature and relative air humidity were measured at 7, 14 and 21 o'clock. the gas composition and the air movement rate were periodically investigated. it was established that at temperatures ... | 1979 | 549260 |
| crown gall: economic importance and control. | many plants of economic importance are possible hosts for agrobacterium tumefaciens, the causal organism of the crown gall tumor disease. damage has been reported on stone fruit (australia), vineyard (hungary, bulgaria), lettuce (brasil) ... in western-europe, crown gall seems to be of less economic importance for plants growing in the open air. however, plants cultivated in greenhouses have a greater chance to be tumorized, because of the more favourable circumstances for tumor induction. moder ... | 1979 | 549390 |
| [electron microscopical evidence of spiroplasma citri in nucleus of infected testplants (author's transl)]. | this is the first report for the evidence of mycoplasmas in an organelle of a plant cell. spiroplasma citri was detected by electron microscopy in the nucleus of a phloem parenchyma cell of chrysanthemum carinatum schousboe plants, inoculated experimentally by euscelis plebejus fall. | 1979 | 549392 |
| abrupt (sharp cut) type sensorineural hearing loss--a human temporal bone study--. | histopathology of a case of bilateral sensorineural hearing loss of abrupt (sharp cut) type is reported. while there was a 45 db gap in threshold between 1,000 hz and 2,000 hz bilaterally, the patient had a good hearing at 1,000 hz and lower frequencies. the patient was suffering from takayasu's arteritis. major histopathological findings were as follows: almost complete loss of the outer hair cells from the basal end to 12 mm area in the left cochlea (length: 30.5 mm) and 13 mm in the right (le ... | 1979 | 549560 |