| [genetic transformation of streptococci]. | | 1976 | 785057 |
| a rationale for intraperitoneally administered antibiotic therapy. | a satisfactory clinical response occurred in 96.7 per cent of 210 patients with proved bacterial peritonitis following appropriate surgical intervention and an antimicrobial regimen of 1 per cent cephalothin administered intraperitoneally, with supplementary antibiotics as indicated. instillation of cephalothin achieves the therapeutic benefits of high intraperitoneal levels with an antibiotic of broad activity and minimum toxicity and permits flexibility in the choice of additional antimicrobia ... | 1976 | 785645 |
| [current hospitalismus. contribution to the causal factors of problem infection from the bacteriological view point]. | | 1976 | 785871 |
| [the influence of pivmecillinam on the human gut flora (author's transl)]. | the effect of pivaloyloxymethyl ester of 6-beta-[(hexahydro-1h-azepin-1-yl)-methyleneamino]-penicillanic acid (pivmecillinam, fl 1039) on the gut flora of human subjects was investigated at different doses. following administration of 1.2 g or 2.4 g/die e. coli and other enterobacteriaceae species were markedly reduced. the response of enterococci and bacteroides species showed no uniformity. no overgrowth of the gut flora by pseudomonas, staphylococci or candida was observed. meanwhile it has b ... | 1976 | 786300 |
| formation of crystalline deposits by several genera of the family enterobacteriaceae. | several species of bacteria from the family enterobacteriaceae formed crystalline materials containing calcium when grown in a defined culture medium. enterobacter aerogenes, proteus vulgaris, citrobacter freundii, and c. intermedius produced calcium pyrophosphate crystals. edwardsiella tarda and escherichia coli formed calcite iii crystals, whereas proteus mirabilis, klebsiella pneumoniae, providencia stuartii, and serratia marcescens produced hydroxyapatite crystals. several of these bacteria ... | 1976 | 786887 |
| inhibitory effect of heparin on the limulus test for endotoxin. | heparin can inhibit the limulus test for endotoxin unless 0.05 m cacl(2) and 0.154 m nacl are added to the lysate. | 1976 | 787001 |
| rapid microbiologic assay of tobramycin. | different, rapid, plate diffusion assays of tobramycin in serum were compared with each other and with an overnight assay. these assays were done with klebsiella edwardsii var. atlantae, which was resistant to many antibiotics. one of the rapid assays of tobramycin tested used a 1:50-1:100 dilution of an overnight culture, and results were recorded after incubation for 5 hr at 35 c. two shorter assays were also tested with a 1:10 dilution of an overnight assay. the 5-hr assay was as reproducible ... | 1976 | 787447 |
| intrathecal amikacin administration. use in the treatment of gentamicin-resistant klebsiella pneumoniae meningitis. | | 1976 | 787564 |
| adjuvant action of capsular polysaccharide of klebsiella pneumoniae on antibody response. v. further biological properties of the active substance. | the neutral fraction (neutral cps-k) of klebsiella pneumoniae capsular polysaccharide (cps-k) from type 1, kasuya strain, has already been reported as the active substance responsible for the strong adjuvant effect of cps-k. the present results demonstrate that neutral cps-k exhibits further common biological activities with lipopolysaccharide (lps) isolated from salmonella enteritidis. the intensity of the lethality in mice of neutral cps-k by the intraperitoneal route is very similar to that o ... | 1976 | 787603 |
| a naturally acquired infection of laboratory mice with klebsiella capsule type 6. | an epizootic causing high morbidity and high mortality in swiss white and nude mice over a period of 3 weeks was caused by klebsiella pneumoniae capsule type 6, which is considered to be nonpathogenic for mice. experimental inoculation of this organism into laboratory animals caused death within 36 hours, further substantiating its virulence. | 1976 | 787669 |
| [lytic properties of klebsiella ozaenae phages]. | | 1976 | 787732 |
| sensitivity patterns of urinary pathogens in the southland community and a study of sewage flora. | the overall sensitivity pattern of the three main urinary pathogens to the commonly used oral antibodies exceeded 80 percent. the incidence of multiple resistant escherichia coli was 8 percent. the resistant patterns of the sewage e. coli resembled that of the resistant urinary e. coli. however only one-third of the resistant urinary e. coli showed multiple resistance whereas two-thirds of the resistant e. coli in the sewage showed this feature. the resistance transfer was low in organisms isola ... | 1976 | 787846 |
| the bactericidal action of benzoic acid and sodium acetate on the gram-negative flora of dialysis fluid. | benzoic acid in concentrations from 0.18 per cent and upwards exerted a bactericidal action on the gram-negative flora of dialysis fluid at ph 4.75 in vitro. at a concentration of 0.32 per cent, a reduction of 10(5) was obtained with 24 hours. sulphonamide resistance did not affect the bactericidal action. the killing effect was hardly more than directly proportional to the concentration of benzoic acid. increasing inoculum decreased the bactericidal effect. therefore, benbzoic acid should not b ... | 1976 | 788461 |
| [essential characteristics of the etiopathogenetic factors in scleromatous granuloma]. | | 1975 | 788649 |
| gentamicin-associated acute renal failure. | five patients are described in whom only gentamicin sulfate appeared responsible for acute renal failure. subjects received 1.2 to 2.88 gm over 12 to 18 days. all were over 45 years of age, and premorbid kidney abnormalities may have enhanced susceptibility to toxic effects of the drug. renal failure appeared 8 to 17 days after beginning gentamicin therapy and was characterized by creatinine clearances 4 to 10 ml/min, urine to plasma creatinine ratios less than 20, urinary sodium concentrations ... | 1976 | 788666 |
| comparative studies on the actions of antigen and polyclonal b-cell activator in differentiation and proliferation of b-cells and b memory cells. | using the capsular polysaccharide of klebsiella pneumoniae (cps-k) as a polyclonal b-cell activator (pba) and sheep red blood cells (srbc) as a t cell-dependent antigen, we compared the ability of pba and antigen to differentiate (generate antibody-forming cells, afc) and proliferate (generate immunological memory) virgin b cells and b memory cells. in vitro cps-k induced the differentiation of igm virgin b cells, igm b memory cells and igg b memory cells to afc, as well as or better than srbc. ... | 1976 | 789231 |
| [bacteriological studies in outpatients with acute urinary tract infections with particular reference to the resistance spectrum (author's transl)]. | bacteriological investigation of urinary samples from 1,926 non-hospitalised patients with documented or suspected acute urinary tract infection revealed organisms pathogenic for the urinary tract in 56.4% of the patients, who came from various parts of west germany. prevalent pathogens were e. coli (69%) and proteus mirabilis (14%). e. coli and p. mirabilis demonstrated a low rate of resistance against ampicillin, the cephalosporines, gentamicin, tobramycin, and also against nitrofurantoin, nal ... | 1976 | 789245 |
| [antimicrobial effectiveness of sisomicin. i: in vitro activity of sisomicin compared with gentamicin, tobramycin, amikacin and kanamycin (author's transl)]. | the aminoglycosides sisomicin, gentamicin, tobramycin, amikacin and kanamycin are highly active against staphylococci including the penicillinase-positive strains. sisomicin is more effective than amikacin and kanamycin. mixed infections with staphylococci and enterobacteriaceae or pseudomonas aeruginosa are thus on indication for treatment with sisomicin or other aminoglycosides. infections with e. coli, enterobacter, susceptible klebsiella, and susceptible pseudomonas strains can be treated wi ... | 1976 | 789246 |
| [changes in the antibiotic sensitivity of urinary tract pathogens (author's transl)]. | the resistance of 2,314 bacterial strains from 1968 to 1972 was investigated drawing on case histories from the munich university urological clinic. using the disc-diffusion method 12,160 sensitivity tests were conducted with these strains against gentamicin, co-trimoxazole, ampicillin, tetracycline and chloramphenicol. the material was compiled from 35,000 individual data by means of modern electronic data processing and evaluated according to variable criteria. as expected the incidence of res ... | 1976 | 789247 |
| [the liver concentration of cephradin and cephacetril and their elimination in the bile]. | liver biopsies and serum samples were collected after intravenous application of 2 g cephradin (n = 13) or 2 g cephacetril (n = 11) during surgery. there was no difference in the serum levels of cephradin and cephacetril. 30 min. after i.v. application of cephradin the liver tissue concentration was 72.62 mcg/g. 30 min. after i.v. cephacetril the liver tissue concentration was 5.83 mcg/g. the quotient of liver tissue concentration to serum concentration for cephradin was between 0.36 and 0.83, a ... | 1976 | 789253 |
| mutational alteration of a nitrogen-fixing bacterium to sensitivity to infection by bacteriophage mu: isolation of nif mutations of klebsiella pneumoniae m5al induced by mu. | the nitrogen-fixing bacterium klebsiella pneumoniae m5al is not sensitive to infection by bacteriophage mu. a mutant of k. pneumoniae that is sensitive to mu infection was isolated. several mu-induced auxotrophic mutations of k. pneumoniae including nif, trp, and rtl were isolated and genetically characterized. evidence is presented that the mu-induced mutations of nif arise as the result of insertion of mu within (or near) the nif operon(s). the rtl locus, which determines the ability to utiliz ... | 1976 | 789339 |
| isolation of l-forms by blood culture. | culture media for the isolation of bacterial l-forms from the blood were studied. the most successful media had an osmolality of more than 1100 mosm/kg and this appeared to be a critical factor in determining success. | 1976 | 789403 |
| beta-lactamases and resistance to penicillins and cephalosporins in serratia marcescens. | strains of serratia marcescens fall into one of two groups with respect to their resistance to to beta-lactum antibiotics. most strains are highly resistant to cephalosporins but are significantly more susceptible to ampicillin and carbenicillin, whereas other strains are highly resistant to both penicillins and cephalosporins. strains in the former category produce small amounts of an inducible cephalosporinase, which appears to be chromosomally mediated. strains in the latter class also elabo ... | 1976 | 789784 |
| isolation of rough mutants of klebsiella aerogenes and their synthesis of polysaccharides. | two mutants which lacked both capsular and lipopolysaccharide o-antigen polysaccharides were isolated from klebsiella aerogenes serotype 2 by phage selection; these were designated rough mutants. the polysaccharide fractions solubilized by partial acid hydrolysis of the lipopolysaccharide from both the wild type and mutants were chromatographed on sephadex g-50. analysis of the fractions obtained confirmed that the rough mutants lacked the galactan portion of the molecule, which is analogous to ... | 1976 | 789814 |
| the urographic findings in acute pyelonephritis: non-obstructive hydronephrosis. | excretory urography was performed on 4 patients early in the course of acute pyelonephritis. these studies showed dilatation of the involved collecting system without obstruction. the dilatation resolved after therapy in 3 patients and was not present on a previous excretory urogram in the fourth. although previous studies have shown that the excretory urogram is usually normal in cases of acute pyleonephritis these cases demonstrate that this disease can produce dilatation of the collecting sys ... | 1976 | 789916 |
| [control of cross infection in intensive care units]. | quantitative determinations of antibiotic susceptibility established that infections occurring in intensive care units were predominantly exogenous cross infections. the most frequently isolated strains were: klebsiella, enterobacteriaceae, serratia marcescens and proteus mirabilis. the majority of the strains showed multiple resistance. despite adequate antibiotic therapy a number of patients died of the infection. many of the methods of disinfection were found to be inadequate, especially as r ... | 1976 | 790370 |
| [disinfection of the inspired and expired air during artificial respiration with humified gases]. | the water in the nebulizer of respirators is a potential source of infection for patients receiving artificial respiration. interposition of a special equipment that will produce ozone-free ultraviolet radiation will prevent infection of the patient by the inspired humidified air, even if the bacterial count in the nebulizer fluid is very high. interposition of the same equipment on the expiratory side is also recommended to minimize the risk of infection of the environment by bacteria in the ex ... | 1976 | 790371 |
| [polyallergic (concomitant) reactions to bacterial allergens in patients with pre-asthmatic conditions and infectious-allergic bronchial asthma]. | | 1976 | 790594 |
| five-day course of antibacterials for uncomplicated urinary infections. | fifty-six patients with uncomplicated urinary infections were treated with a five-day course of antimicrobials. fifty-four patients had sterile urine two weeks after termination of the drugs. over a two-year period 8 patients were found to become reinfected. | 1976 | 790745 |
| [comparative studies with the rapid kcn-test for enterobacteriaceae according to cahan, sechter and ohad (author's transl)]. | 581 strains of enterobacteriaceae (184 of salmonella, 100 of shigella, 31 of citrobacter freundii, 61 of escherichia coli, 40 of klebsiella, 165 of proteus) were investigated in comparison with the kcn-test according to møller and with the rapid kcn-test according to cahan, sechter and ohad. there was found that the results obtained with both methods were identical to 99 percent. in both tests there could be observed that inexplicable differences occur only in two strains of proteus mirabilis. t ... | 1976 | 790855 |
| inositol as a selective substrate for the growth of klebsiellae and serratiae. | a synthetic basal salts medium containing inositol as the sole source for carbon and energy and bromothymol blue as ph indicator, selectively supports the growth of klebsiella pneumoniae and serratia spp. on this medium incubated at 37 degrees c for 24 hr, all cultures of kl. pneumoniae, serratia liquefaciens and s. marcescens form yellow colonies. the medium may be used selectively for the primary isolation of the aforementioned bacteria from faeces and as a differential medium for their isolat ... | 1976 | 790856 |
| human oral defenses against gram-negative rods. | gram-negative rods are unusual pharyngeal isolates in normal man, which suggests the presence of effective oral defense mechanisms against these organisms. to understand this protection better, we studied the elimination of gram-negative rods from the mouth after gargle challenge. suspensions of escherichia coli, klebsiella pneumoniae, and proteus mirabilis (108 organisms per ml) were gargled by normal volunteers, and pharyngeal swabs for serial quantitative cultures were taken for 3 hours. init ... | 1976 | 791034 |
| susceptibility of acinetobacter calcoaceticus var. anitratus (herellea vaginicola) to minocycline. | the in vitro activity of minocycline against acinetobacter calcoaceticus var. anitratus (herellea vaginicola) was examined. all strains of a. anitratus were inhibited by minocycline at concentrations of 0.4 mug/ml or less. the strains studied were considerably more susceptible to minocycline than tetracycline. no difference between the susceptibility to minocycline and tetracycline was seen with escherichia coli, klebsiella pneumoniae, enterobacter and proteus sp. a regression line of the log mi ... | 1976 | 791084 |
| r factor-mediated antibiotic resistance in serratia marcescens. | nineteen of 39 multiresistant strains of serratia marcescens isolated from clinical sources transferred antibiotic resistance to escherichia coli or klebsiella pneumoniae recipients. marcesins and/or phage prevented effective resistance transfer to e. coli and attempts to select marcescin-resistant mutants of the e. coli recipient strain were unsuccessful. transfer of resistance was demonstrated for all drugs tested except nalidixic acid. approximately 90% of donors resistant to tobramycin, ampi ... | 1976 | 791085 |
| in vitro synergistic effect of netilmicin, a new aminoglycoside antibiotic. | the combination of netilmicin (sch 20569) with carbenicillin, cefazolin, chloramphenicol, and clindamycin was evaluated by in vitro tests against 91 clinical isolates of pseudomonas, klebsiella, and escherichia coli. combinations were considered to show synergy if there was a fourfold or greater reduction in minimal inhibitory concentration values of both antibiotics when combined. synergy of netilmicin with carbenicillin could be demonstrated against 21 of 46 pseudomonas isolates. comparison of ... | 1976 | 791104 |
| oxygen transfer rate, respiration and yields in batch and chemostat cultures of klebsiella aerogenes. | the effect was studied of oxygen supply on the changes in total and specific rate of oxygen consumption by the cells, oxygen transfer rate, saturation concentrations of dissolved oxygen and the yields of batch and continuous cultivations. experiments were done on the microorganism klebsiella aerogenes ccm 2318 growing on synthetic glucose medium. continuous cultivations were carried out at dilution rates of 0.96 and 0.178 h-1. the rate of oxygen transfer was determined by the sulphite method and ... | 1976 | 791773 |
| in vitro growth inhibition of mastitis-causing coliform bacteria by bovine apo-lactoferrin and reversal of inhibition by citrate and high concentrations of apo-lactoferin. | bovine apo-lactoferrin (apo-lf) was added to in vitro cultures of eight strains of coliform bacteria associated with bovine mastitis. as little as 0.02 mg of apo-lf per ml resulted in marked inhibition of growth of all coliforms. growth inhibition was lost if saturated lf or iron plus apo-lf was added to the synthetic medium. the inhibition of growth increased as the concentration of apo-lf increased from 0.02 to 0.2 mg/ml for klebsiella pneumoniae (oardc-a1), klebsiella spp. (k1-21), and aeroba ... | 1976 | 791866 |
| use of bacteriophage mu to isolate deletions in the his-nif region of klebsiella pneumoniae. | klebsiella pneumoniae m5a1 is naturally resistant to infection by bacteriophage mu. mutants of k. pneumoniae sensitive to mu infection were isolated and found to support both lytic and lysogenic development of mu. k. pneumoniae lysogens containing a heat-inducible mu prophage integrated in his were isolated. strains carrying deletions extending from his into nif were obtained after heat treatment of these lysogens. such deletions should be useful for determining the map order and cistronic organ ... | 1976 | 791929 |
| clinical evaluation of the minitek differential system for identification of enterobacteriaceae. | forty-one stock organisms and 581 fresh clinical isolates were used in comparing the minitek system to conventional tubed media to determine if this system is feasible and accurate for a high-volume clinical microbiology laboratory. in addition to comparison with tubed media, the following parameters were tested: (i) reproducibility of disks, (ii) the effect of variation in inoculum size, (iii) the effect of the age of culture, and (iv) the effect of predispensing disks. a total of 5,947 disks w ... | 1976 | 791964 |
| toxigenic bacterial diarrhea: nursery outbreak involving multiple bacterial strains. | an outbreak of watery diarrhea occurred in 14 of 15 infants in a special care unit over a four-day period. using the cho cell assay for enterotoxin, we found that 11 of these patients had toxigenic bacteria in their stools. these bacteria comprised nine different serotypes of three species of organisms: escherichia coli, klebsiella, and citrobacter. none of the three serotypes of e. coli were classic enteropathogenic serotypes. rectal swab specimens from all 15 infants were examined for the pres ... | 1976 | 792408 |
| a study of bacterial aerosols at a wastewater irrigation site. | | 1976 | 792471 |
| effect of cephalothin on growth patterns of micro-organisms. | isolates of staphylococcus aureus, escherichia coli. klebsiella pneumoniae and proteus mirabilis were incubated in the presence of inhibitory concentrations of cephalothin. after destruction of the antibiotic, there was a lag phase before s. aureus began to proliferate again. when similar experiments were conducted with e. coli, k. pneumoniae, and p. mirabilis, no lag phase was observed. this data suggests that the inhibitory activity of cephalosporins may be different for gram-positive cocci an ... | 1976 | 792494 |
| effect of capsular polysaccharide of klebsiella pneumoniae on host resistance to bacterial infections. ii. effects on peritoneal leukocytes of normal mice and mice infected with virulent salmonella enteritidis. | in normal mice, the total count of peritoneal leukocytes was markedly decreased after intraperitoneal (i.p.) injection of the capsular polysaccharide of klebsiella pneumoniae (cps-k) depending on the dosage injected. this decrease was mainly due to the depletion of macrophages, and a decrease in the number of lymphocytes occurred to a lesser extent. cps-k in relatively smaller doses mobilized polymorphonuclear neutrophilic leukocytes (pmn) into the peritoneal fluid but it decreased them transien ... | 1976 | 792533 |
| cadmium and zinc sensitivity and tolerance in klebsiella (aerobacter) aerogenes. | the resistance of strains of k. aerogenes ncib 418 'trained' to cd2+ or zn2+ in liquid medium is graded to the training concentration. training to cd2+ increased the sensitivity to zn2+ but training to zn2+ reduced the sensitivity to cd2+. the trained organisms, particularly those trained to cd2+, grow slowly in medium containing the metals and the growth rates after 20 and 200 subcultures were not significantly different. the survival of untrained organisms on cd2+-agar decreased progressively ... | 1976 | 792633 |
| the butanol-soluble proteins of klebsiella aerogenes. | membranes of klebsiella aerogenes were extracted with acid butanol at ph 4.2 and the solubilized proteins were fractionated by precipitation at 0 degrees c and -20 degrees c. the -20 degrees c precipitate was examined by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. several enzyme activities associated with polysaccharide biosynthesis have been identified in the crude -20 degrees c precipitate and an attempt was made to separate the enzymes from other protein. the role of certai ... | 1976 | 792634 |
| oral manifestations of crohn's disease: studies in the pathogenesis. | | 1976 | 792883 |
| [effect of hyperbaric oxygen on aerobic bacteria]. | the authors investigated the growth of 8 species of pathogenic aerobic bacteria after treatment with hyperbaric oxygen. within 24 hours the cultures were exposed three times for 2 hours to an absolute pressure of 3 atmospheres of oxygen at 37 degrees c. in the fluid cultures as well as in the controls the inhibitory effect of oxygen was assessed in percent by means of the densitometric method. from these in vivo experiments the authors conclude that hyperbaric treatment of superficial pyogenic e ... | 1976 | 793215 |
| enterobacteriaceae in the jejunal microflora prevalence and relationship to biochemical and histological evaluations in healthy colombian men. | when 23 healthy native southwestern colombian men were studied to determine the prevalence of enterobacteriaceae in the jejunal microflora in a sample of thoroughly evaluated tropical inhabitants who were normal by physical examination, chest x-ray, and medical history, 14 of the 23 proved to be enterobacteriaceae-positive, with counts of 10(3) to 10(9) per milliliter of jejunal aspirate. thirteen had escherichia coli, and the fourteenth had klebsiella pneumoniae. four had a second species of en ... | 1976 | 793372 |
| radiologic features of gram-negative pneumonias in the neutropenic patient. | while gram-negative pneumonia is a frequent complication in immunosuppressed patients with malignant disease, the diagnosis is difficult to establish. clinical and radiographic study of 195 episodes of pneumonia in 175 consecutive patients was undertaken. chest radiographs were negative in 19% of the episodes, probably due to absence of alveolar inflammatory cell infiltrate. radiographic patterns were classified as either alveolar or mixed alveolar and interstitial; no case of interstitial patte ... | 1976 | 793427 |
| [experimental study of the chemotherapeutic activity of gentamicin sulfate]. | antibacterial activity of gentamycin sulfate was studied in vitro and in treatment of albino mice with experimental infections. gentamycin was superior to kanamycin with respect to its antibacterial effect against clinical strains of staphylococcus, coli bacteria, proteus and ps. aeruginosa. high efficiency of gentamycin was found with respect to acute and chronic staphylococcal infection, acute proteus and coli sepsis. the antibiotic was characterized by low ld50, high chemotherapeutic index, r ... | 1976 | 793517 |
| evaluation of double violet agar in the isolation of klebsiella pneumoniae from river water. | a field evaluation of double violet agar for the isolation and presumptive identification of klebsiella pneumoniae from water has been performed. water from the north oconee river, clarke county, ga., was cultured for presence of klebsiellae using the membrane filter technique. colonies were presumptively identified as k. pneumoniae in the basis of their appearance on double violet agar. such identifications were evaluated using appropriate biochemical tests. once investigators have become famil ... | 1976 | 793520 |
| [clinical significance of sperm pathogens in fertility disorders]. | the reasons for systematic microbial examinations of human ejaculates are discussed. the exact establishment of an association between bacteria isolated from human ejaculates and infertility is very difficult. there are several hints for such an association in the case of different micoplasmas though there is no clear-cut evidence. a physical association between these microorganisms and spermatozoa, which was recently observed, possibly could help to facilitate the diagnosis. | 1976 | 793968 |
| simplified scheme for identification of prompt lactose-fermenting members of the enterobacteriaceae. | a brief, simplified scheme involving the spot indole test and colonial morphology was evaluated for genus level identification of prompt lactose-fermenting (plf) members of the enterobacteriaceae. one hundred and ninety-four consecutive, clinically important plf gram-negative rods isolated in a clinical microbiology laboratory were identified by this simplified scheme, as well as by standard biochemical tests, and the api 20e (analytab products, inc., plainview, n.y.) system. in the simplified s ... | 1976 | 794078 |
| klebsiella and enterobacter organisms isolated from horses. | an account is given of k. pneumoniae capsule types occurring in horses, with particular reference to strains originating from the genital tract in the mare and the external genitalia of the stallion. a survey of the prevalence of k. pneumoniae and e. aerogenes strains in the preputial flora of healthy stallions is described. the majority of horses were found to be carriers of these organisms. the cultural characteristics of these preputial strains are described and compared with those of k. pneu ... | 1976 | 794407 |
| role of b-lymphocytes in nonspecific resistance to klebsiella pneumoniae infection of endotoxin-treated mice. | lipopolysaccharides (lps) of gram-negative bacilli are known to protect mice against unrelated bacterial infections and to be nonspecific mitogens of murine bone marrow-derived (b-) lymphocytes. for assessment of the role of these cells in the mechanism of lps-induced resistance to infection with klebsielia, various nontoxic mitogens were assayed. in contrast to lps or lipid a, the nontoxic mitogens did not protect mice. experiments were also performed with lps in nude mice and in mice treated w ... | 1976 | 794421 |
| [rhinoscleroma with sinuso-orbitary invasion]. | the authors present the case of an 11-year-old child with a slowly progressive tumoral invasion resulting in bilateral nasal obstruction, massive facial deformation, and an exophthalmos of the left eye. there was no impairment of the child's general health. the histological investigation revealed the presence of mikulicz' cells and von frisch's bacilli. the resultant diagnosis was rhinoscleroma. | 1976 | 794784 |
| biochemistry and genetics of nitrate reductase in bacteria. | | 1976 | 795276 |
| [etiology of pyelonephritis in pregnant and parturient women]. | | 1976 | 795316 |
| isolation of klebsiella pneumoniae from lake water. | the question of the importance of aquatic borne klebsiella pneumoniae to public health has been argued as the organism has appeared often in both polluted effluents and oligotrophic systems. using a selective medium, double violet agar, which also differentiates k. pneumoniae from other organisms found in aquatic systems, we sampled water from three ponds and a large man-made lake, over a 3-month period. results indicate that k. pneumoniae can be isolated consistently and in high numbers from eu ... | 1976 | 795534 |
| presumptive identification of klebsiella pneumoniae on m-fc medium. | klebsiella pneumoniae is a human and animal pathogen frequently encountered in the environment. the membrane-filtration method utilizing m-fc medium for the detection of fecal coliforms yields a colony type easily distinguishable as k. pneumoniae. these colonies appear as atypical light blue, nucleated, mucoid colonies differing considerably from the typical dark blue fecal coliform colonies. | 1976 | 795536 |
| the lactose system of klebsiella aerogenes v9a. 5. lac-permease defective mutants of two klebsiella lac plasmids and their apparent reversion to wild type. | | 1976 | 795725 |
| immunofluorescence detection of nitrogenase proteins in whole cells. | fluorescent antibodies (fa) prepared against the mo-fe and fe proteins of nitrogenase from klebsiella pneumoniae m5ai were used to detect these protein components in toluene-treated whole cells that were actively reducing acetylene. the fa were highly specific, staining only nitrogenase component proteins originating from klebsiella. cross-reactions between the fa and purified nitrogenase proteins from other dinitrogen-fixing micro-organisms did not occur, except in the case of bacillus polymyxa ... | 1976 | 796412 |
| [comparative results of cephacetrile with cefazolin in complicated urinary tract infections by means of double-blind trials (author's transl)]. | in order to elucidate the usefulness of cephacetrile (cec), comparative trials with cefazolin (cez) were carried out in the patients with complicated infections of the urinary tract, and the following results were obtained: 1. there were no statistically significant differences or tendencies observed between the groups given cec and cez in either of the global effects, bacteriological effects, rate of superinfection, relapse, relapse with bacterial alternation, drug usefulness, rate of improveme ... | 1976 | 796485 |
| studies on the effect of phytagglutinins on some members of enterobacteriaceae. | extracts of twenty seeds were tested against twenty six organisms belonging to klebsiella, proteus, salmonella, shigella and cholera species. extracts of eleven seeds showed agglutinating activity against twenty four various organism. s. typhi and kl. aerogenes did not react against any lectin. on the basis of the results it was possible to differentiate various shigella and salmonella organisms by various seed extracts. different isolates of cholera organisms of same serotype and phage type sho ... | 1976 | 796502 |
| [role of conventionally pathogenic/intestinal bacteria in surgical practice (literature survey)]. | | 1976 | 796557 |
| the mutagenicity of cyclamates and their metabolites. | | 1976 | 796692 |
| [rhinoscleroma in an immigrant]. | a patient with rhinoscleroma was treated in our department. as far as we know it is the first importcase published in belgium. rhinoscleroma is an infectious disease caused by the klebsiella rhinoscleromatising. it is a chronic granulomatous process with subsequent stenosis and scarring. the nose and larynx are the most frequent localisations. the therapy consists of antibiotics in an early stage and is only palliative in the latter ones. | 1976 | 797230 |
| [systematic study of pharyngeal and nasal bacteria in children affected by relapsing diseases of respiratory organs (author's transl)]. | the research was conducted on 191 nasal and pharyngeal swabs from children aged between two and ten years, affected by relapsing diseases of their respiratory organs. the aim has been that of isolating those bacteria whose action cause the most frequent respiratory diseases. they are: haemophilus influenzae, staphylococcus c+, klebsiella pneumoniae, pseudomonas and other gram-negative bacteria. the isolated bacteria were submitted to sensitivity tests and to the normally used antibiotics. from t ... | 1976 | 797320 |
| [comparative analysis between qualitative and quantitative features of orofaringeal and tracheo-bronchial bacterial flora in normal subject (author's transl)]. | in 28 subjects surely without tracheo-bronchial phlogosis it had been observed that the trachea and the bronchi are mostly sterile, only rarely there is a normal bacterial flora. in the mouth and in the pharynx there is instead, almost always, normal bacterial flora and only exceptionally potentially pathogenous strains at a concentration inferior to 10(7). | 1976 | 797321 |
| [gentamicin resistance and the r factor in the strains isolated from the urinary tract (author's transl)]. | | 1976 | 798057 |
| [relationship between the ultrastructure and chemical composition of the capsula in klebsiella rhinoscleromatis]. | | 1976 | 798151 |
| effect of dietary oxytetracycline on microorganisms in turkey feces. | thirty-six two-day old male turkey poults were divided into three groups and fed three levels of oxytetracycline; 0, 110 or 440 mg. per kg. of ration, respectively, for nine weeks. the poults were given an oral spectinomycin plus vitamin treatment at the hatchery but were not fed before the start of the experiment. defecated feces from each group were sampled at weekly intervals and analyzed for bacteriological content, especially for members of the enterobacteriaceae. total aerobic counts of 3 ... | 1976 | 798178 |
| [experimental pyelonephritis in rats: value in the comparison of antibiotics (author's transl)]. | the author discusses the conditions which an experimental pyelonephritis must fulfill to provide therapeutic results which will allow the assessment of new therapeutic agents. he subjects the chosen model to the therapeutic effect of four antibiotics and three antimicrobial drugs. a numeric value is given to the bacteriuria recession slope observed during the experiment. a comparison of the results being obtained with the bacteriological and pharmacological data normally evaluated, the author de ... | 1976 | 798516 |
| some clinical and radiological aspects of the toxic enteritis in suckling age. | | 1976 | 799607 |
| [urinary tract infections in adolescents. results of bacteriological-urine screening within the scope of school-health examinations]. | | 1975 | 801081 |
| [oxolinic acid therapy of urinary tract infections in infancy]. | | 1976 | 801102 |
| bladder defense mechanism. | in order for micro-organisms to infect the urinary tract they must adhere to the vesical mucosa so that they remain after voiding. experiments in our laboratory demonstrated that the bladder has a self-protective mechanism capable of preventing bacterial adherence to the surface. histochemical staining demonstrated that this substance is a mucopolysaccharide. treatment of the mucosa with acid disrupted the protective layer and resulted in a 20 to 100-fold increase in bacterial adherence. within ... | 1976 | 801214 |
| gram negative septic shock. | | 1975 | 801269 |
| invitro studies of the effect of bilharcid on urinary tract bacterial pathogens. | the antimicrobial effect of an antibilharzial drug "bilharcid" was tested, in vitro, against 51 different strains of bacterial species frequently causing urinary tract infection namely e. coli, staphylococcus aureus, klebsiella, ps. pyocyanea and proteus vulgaris. in addition, the drug was tested against one strain of each of salmonella typhi, salmonella paratyphi a. b and c. minimum inhibitory concentration (m.i.c.) of the drug for each organism, and its bactericidal concentration were determin ... | 1976 | 801712 |
| degradation of n-nitrosamines by intestinal bacteria. | a major proportion of bacterial types, common in the gastrointestinal tract of many animals and man, were active in degrading diphenylnitrosamine and dimethylnitrosamine, the former being degraded more rapidly than the latter. at low nitrosamine concentrations (is less than 0.05 micronmol/ml), approximately 55% of added diphenylnitrosamine, 30% of n-nitrosopyrrolidine, and 4% of dimethylnitrosamine were degraded. the route of nitrosamine metabolism by bacteria appears to be different from that p ... | 1975 | 803287 |
| use of tergitol-7 agar in the clinical laboratory. | tergitol-7 agar has been utilized in the author's laboratory for eight years and has been found the superior medium for the rapid isolation, separation and identification of gram negative bacilli found in a clinical setting. | 1975 | 803348 |
| necrotizing enterocolitis. | the clinical course of 54 patients with necrotizing enterocolitis has been compared to a matched group of 98 control patients. on the day of life that nec occurred, all 54 nec patients and 63% of controls were receiving standard formula feedings, both at 80/cal/kg/day. stool cultures at the time revealed a significantly increased frequency of klebsiella in nec as compared to control patients. our data suggest that the combined presence of certain intestinal bacteria and enteric feedings, perhaps ... | 1975 | 803385 |
| the role of vaginal colonization with enterobacteriaceae in recurrent urinary infections. | quantitative cultures of the vaginal introitus for enterobacteriaceae, s. faecalis and p. aeruginosa were compared in 20 premenopausal normal women (200 cultures) to 198 consecutive cultures from 9 premenopausal women in between episodes of bacteriuria. introital colonization in patients susceptible to urinary infections was significantly higher for e. coli (p equals 0.001), s. faecalis (p equals 0.001) and for the presence of any gram-negative pathogens (p equals less than 0.001). in addition, ... | 1975 | 803573 |
| computer surveillance of shifts in the gross patient flora during hospitalization. | data accumulating routinely in a hospital microbiology laboratory were computer-plotted according to the number of days the patient had been in the hospital when each culture was obtained. the rate at which patients were cultured fell slightly during hospitalization, while the rate at which isolates were obtained from them increased gradually. for some species, such as escherichia coli or staphylococcus aureus, isolation rates changed little during hospitalization. they rose as much as sevenfold ... | 1975 | 804021 |
| rapid detection and identification of enteric bacteria from blood cultures. | the bactec radiometric system and inolex enteric i card were used in conjunction for the rapid detection and presumptive identification of enteric gram-negative rods in blood cultures. excellent correlation was obtained between the inolex card and routine identification techniques when organisms from both artificially inoculated and clinical blood cultures were studied. in many instances, the culture report was available less than 24 hr after receipt of the specimen. | 1975 | 804025 |
| comparison of amikacin and gentamicin. | the sensitivity to gentamicin (g) and to amikacin (a) of 25 strains of escherichia coli (ec), 25 klebsiella sp. (k), 25 proteus and providence sp. (pp), and 25 ps. aeruginosa (pa) were tested in vitro by the disc method, by the inocula-replicating method, and by a tube dilution technique using 10-5 microorganisms/ml. bactericidal concentrations active on 50% and 90% of the strains were 1.5 and 4.5 mug/ml for ec, 3 and mug/ml for k, 1.5 and 3 mug/ml for pp, and 3 and 3 mug/ml for pa. resistance t ... | 1975 | 804370 |
| herd studies on coliform mastitis. | escherichia coli, enterobacter aerogenes, and klebsiella pneumoniae were responsible for 63, 10, and 11 percent, respectively, of 158 coliform organisms recovered from mastitis cases in 8 california herds. the severity and nature of the coliform mastitis problem were found to vary greatly among herds but were characteristic for each of 4 herds studied in detail. | 1975 | 804464 |
| a membrane filter technique for testing disinfectants. | a membrane filter was used for assessing the surface disinfecting activity of phenolic disinfectants and a chloroxylenol disinfectant. the influence of the type of organism, inoculum size, and hardness of water was investigated. pseudomonas aeruginosa was chosen for the standardized test. disinfectant solutions were prepared in water of 300 ppm hardness and applied for two and a half minutes and eight minutes to the bacteria deposited from filtration of 1 ml of a suspension containing 10-6 bacte ... | 1975 | 804497 |
| immunodeficiency and infantile bone and joint infection. | fifteen patients with infantile bone and joint infections were studied immunologically and clinically, 3 at the time of illness and 12 later. abnormality of immunoglobulins, or complement, or phagocytes was found in 9 patients; 6 were within normal limits for the tests undertaken. immunodeficiency is probably responsible for the subdued clinical signs of infection and for delayed diagnosis in some patients. it was also related to the extent of femoral head damage in infective arthritis of the hi ... | 1975 | 804866 |
| qualitative assessment of midstream urine cultures in the detection of bacteriuria. | 3550 women attending cervical smear and family planning clinics have been screened for bacteriria. suprapubic aspiration of urine was carried out in 131 patients from whom two consecutive midstream urine specimens contained either a pure growth of gram positive cocci or a growth in which gram negative bacilli predominated. 95 patients were found to have bacteriuria; in 93 the urine was infected with a gram negative organism. of 53 patients with a count of more than 10-5 gram negative organisms p ... | 1975 | 805012 |
| antimetabolites produced by microorganisms. xii (s)-alanyl-3-[alpha-(s)-chloro-3-(s)-hydroxy 2-oxo-3-azetidinylmethyl]-(s)-alanine, a new beta-lactam containing natural product. | (s)-alanyl-3-[alpha-(s)-chloro-3-(s)-hydroxy-2-oxo-3-azetidinylmethyl]-(s)-alanine was isolated from a fermentation broth of an unidentified streptomyces species 372 a. the structure was determined by single crystal x-ray diffraction analysis. the substance inhibits the growth of several strains of gram-positive and gram-negative bacteria in a chemically defined medium but growth inhibition is relieved by addition of l-glutamine to the medium. | 1975 | 805110 |
| agglutinin response to bacterial infection in acute exacerbations of chronic bronchitis. | agglutinin titres to haemophilus influenzae, streptococcus pneumoniae, klebsiella pneumoniae, staphylococcus aureus, pseudomonas aeruginosa, escherichia coli, and proteus vulgaris in the serum of patients with acute exacerbations of chronic bronchitis, patients producing mucoid sputum, and healthy controls were determined. serological evidence of infection with h. influenzae was found in 38 of 57 patients with acute exacerbations, and str. pneumoniae infection in 10 of the 57 patients, but was g ... | 1975 | 805163 |
| in-vitro effect of edta-tris-lysozyme solutions on selected pathogenic bacteria. | the in-vitro effect of edta-tris-lysozyme solution on 16 pathogenic bacteria of medical or veterinary importance was determined. marked decreases in bacterial count occurred with pseudomonas aeruginosa, escherichia coli, moraxella osloensis and campylobacter fetus, and smaller decreses with salmonella typhimurium, shigella boydii, aeromonas hydrophila, proteus mirabilis, listeria monocytogenes and erysipelothrix insidiosa. the test solution had no effect on klebsiella ozaenae, brucella canis, co ... | 1975 | 805241 |
| urinary tract infection treated with oxolinic acid. | | 1975 | 805351 |
| lack of mutagenicity of chlormequat chloride in drosophila and in bacteria. | | 1975 | 805365 |
| consequences of microbial contamination during extended intravenous therapy using inline filters. | a study was conducted to determine: (1) the effectiveness of 0.22-mum and 0.45-mum pore size membrane filters in retaining microorganisms over a period of 72 hours of intravenous fluid administration; (2) the growth and multiplication characteristics of microorganisms retained on the filter; and (3) the possibility of pyrogens being released by microorganisms trapped on the filter. lactated ringer's injection was used as the i.v. solution. the 0.45-mum filter was found to be effective in retain ... | 1975 | 805533 |
| effect of antibiotics and osmotic change on the release of endotoxin by bacteria retained on intravenous inline filters. | a study was conducted on the effects of two antibiotics (gentamicin and carbenicillin) and of a sudden change from an isotonic to a hypotonic solution on the release of endotoxin by three gram-negative bacteria(esherichia coli, klebsiella pneumoniae and pseudomonas aeruginosa) growing on a 0.22-mum pore size membrane filter. during a 72-hour constant flow of sterile lactated ringers's solution through the contaminated filters, no endotoxin was released into the filtrates as tested by the coagul ... | 1975 | 805534 |
| comparison of the germicidal activity of prepodyne and betadine surgical scrub solutions. | two iodophoric surgical scrubs soaps, prepodyne and betadine, were evaluated for bacteriocidal activity in a modified phenol coefficient test. a standard inoculum of each of 18 species of microorganisms was mixed with a 1:8 dilution of each iodophor and subcultured after one, three, and five minutes of exposure. complete cidal activty was exhibited by both prepodyne and betadine. twenty-five subjects were tested in hand washing experiments using betadine and prepodyne surgical scrub solutions. q ... | 1975 | 805538 |
| bacteriology of the gallbladder bile in normal subjects. | a bacteriologic analysis of the gallbladder bile in eighty patients who underwent operation was performed in a prospective study. in all twenty patients with a normal gallbladder as assessed by oral cholecystography and intraoperative palpation, cultured were negative. among patients with chronic cholecystitis only 30 per cent had positive bile cultures and this rose to 47 per cent among patients with acute cholecystitis. | 1975 | 805546 |
| asymptomatic bacteriuria in schoolchildren in newcastle upon tyne. | a screening survey for asymptomatic bacteriuria (asb) in 13464 schoolgirls aged 4 to 18 years in newcastle upon tyne showed an overall prevalence of 1.9%. in girls 4 to 6 years it was 1.4%, in girls aged 7 to 11 years it was 2.5%, in girls aged 12 to 18 years it was 1.6%, a statistically significant rise and fall. renal scarring was found in 39 (15%) of 254 girls with asb. neither the prevalence nor the severity of renal scarring increased with age. there was no association between asb and socia ... | 1975 | 805569 |