Publications

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field studies of a reusable polyamide filter for detection of schistosoma haematobium eggs by urine filtration.a reusable monofilament polyamide (nytrel) filter and ninhydrin stained paper filter were compared in syringe filtration of urine to detect schistosoma haematobium eggs in the urine under field conditions. the sensitivity of the technique using the nytrel filter was similar to that of ninhydrin stained paper filters. the quantitative geometric mean s. haematobium egg counts obtained with the nytrel filter were similar to those obtained with the paper filter.19827164164
[schistosomiasis in tunisia. results after 10 years of the endemics control].despite the progress already made in the field of epidemiology and the control of schistosomiasis, the practical application of an efficient and economically acceptable methodology still remains a difficult problem to solve. in the saharian and pre-saharian regions of tunisia, bulinus truncatus was successfully controlled while at the same time most of the infected people were treated, so that the transmission did not show up through the appearance of new cases at the outset of the 2nd semester ...19827165899
[treatment of urinary and intestinal bilharziosis with praziquantel. apropos of 182 cases].182 patients representing 188 cases of schistosomiasis (including 152 s. haematobium, 34 s. mansoni, and 2 s. intercalatum cases) were treated with praziquantel using 40 mg/kg in a single intake. biological check-up did not reveal any abnormality that could have been related to the treatment. clinical side-effects appeared in 25% cases and were essentially gastrointestinal symptoms, headaches, dizziness. efficiency was assessed by direct parasitological examinations of the feces or urine that we ...19827165900
re-evaluation of criteria for making a diagnosis of bilharzia. 19827168853
[treatment of bilharziasis in madagascar. use of oltipraz in mass campaign against s. mansoni and s. haematobium]. 19827170183
protein, glycogen, and water content in schistosomes.the volume of distribution (= vd) of water was measured in schistosoma mansoni, s. haematobium, s. japonicum, and hymenolepis diminuta. in the rat tapeworm, h. diminuta, the volume of distribution of 3h-water was positively correlated with wet weight (r = 0.87, p less than 0.001) and this same phenomenon also was demonstrated in s. mansoni (r = 0.90, p less than 0.001). the 5-sec vdwater was constant over a range of glucose (0.01-50 mm) and phenylalanine (0.01-20 mm) concentrations in both male ...19827175609
resurgence of schistosoma mansoni and schistosoma haematobium after the end of a 4-year control programme against s. mansoni. 19827179424
[comparison of the cercarial chaetotaxy of 10 species of schistosomes].the cercarial chaetotaxy permits the differenciation of four groups of schistosomatinae. --schistosomatium douthitti, parasite of stagnicola and lymnaea (lymnaeidae); --schistosoma japonicum, parasite of oncomelania (melaniidae); --schistosoma mansoni and s. rodhaini, parasites of biomphalaria (planorbiinae, bulinidae); --schistosoma haematobium, s. bovis, s. margrebowiei, s. mattheei, s. leiperi and s. intercalatum, parasites of isidora, physopsis and bulinus (bulininae, bulinidae). for the thi ...19827181377
"control of schistosomiasis": morbidity-reduction and chemotherapy. 19827188153
epidemiology of schistosomiasis. 19827188157
circulating antigens in schistosoma-infections. 19827188159
the effect of praziquantel on schistosoma haematobium, s. japonicum and s. mansoni in primates.baboons infected with s. haematobium and vervet monkeys infected with s. japonicum were treated orally with different dosage regimens of 2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-on e(praziquantel, embay 8440, biltricide) and were autopsied and perfused 3--4 months after treatment. the results suggest that a single oral dose of 75--100 mg/kg body weight is likely to be effective against s. haematobium in the baboon. female worms of s. haematobium are apparently ...19817195244
tolerance and efficacy of praziquantel in phase ii a and ii b therapeutic trials in zambian patients. 19817195247
observations on praziquantel against schistosoma haematobium.1. 2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-one (praziquantel, embay 8440, biltricide) in single oral doses between 15 and 50 mg/kg given to subjects of all ages with schistosoma haematobium infections produced few side effects even at the higher doses. parasitological results were as follows: a) 15--20 mg/kg were too low to consistently give a favourable parasitological response. b) 21--25 mg/kg cured a high proportion of cases but because of poor response in ...19817195249
praziquantel in the treatment of mixed s. haematobium and s. mansoni infections.a randomized single blind stratified study involving 153 patients with mixed s. mansoni and s. haematobium infection showed that 2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-one (praziquantel, embay 8440, biltricide) is effective in giving high cure rates in each infection separately, 66% (64 patients) and 77% (94 patients), respectively. the complete clearance of both infections (i.e., no eggs whether dead or alive) 6 months after treatment was 29% (43 patients). ...19817195257
the planning of a community health model project in an area in egypt (el qalyub) with concomitant occurrence of s. mansoni and s. haematobium.in addition to knowing about the tolerance, efficacy, and safety of a new antischistosomal agent, public health authorities also have a critical need to know the degree to which population-based chemotherapeutic programmes can potentially reduce disease transmission and morbidity. rational nationwide planning on a cost-effective basis is impossible without such information. thus the qalyub project, a major collaborative research effort by the egyptian ministry of health, the us center for diseas ...19817195258
preliminary results of chemotherapy using praziquantel on a large scale in qalyub bilharziasis project where simultaneous infection with s. mansoni and s. haematobium exists. 19817195259
schistosoma species: transmission electron microscopy of the circumoval immune precipitin reaction on eggs. 19817195345
[control of urinary schistosomiasis by 3 annual courses of metrifonate]. 19817197511
experimental epidemiology of schistosomiasis. ii. prepatency of schistosoma mansoni in biomphalaria glabrata at diurnally fluctuating temperatures.the basic hyperbolic relationship established between constant water temperatures and the length of the prepatent period in the snail was tested as diurnally fluctuating temperatures, stimulating natural conditions. diurnal temperature variations are generally summed up by s. mansoni according to the time-temperature product and are independent of the shape of the temperature curve. using a simple hyperbolic formula, the time of prepatency can be calculated for temperatures ranging from 16 degre ...19817198850
schistosoma mansoni and schistosoma haematobium: emergence of schistosome cercariae from snails with darkness and illumination. 19827199480
a comparative study of the vitelline cell in schistosoma mansoni, s. haematobium, s. japonicum and s. mattheei.a comparison is given of the ultrastructure of the vitelline cell in schistosoma mansoni, s. haematobium, s. japonicum and s. mattheei. four stages in development of the vitelline cell have been categorized as follows: stage 1, the undifferentiated cell; stage 2, the developing cell showing the beginning of synthetic activity; stage 3, the developing cell showing active protein synthesis; stage 4, the fully mature vitelline cell. these stages in development have been defined morphologically and ...19827200223
[epidemiologic study of s. haematobium bilharziasis in the rice fields of yagoua (north cameroon) ii. distribution and ecology of intermediate hosts].while inventoring the local malacological fauna and evaluating the density of species acting as intermediate hosts of human schistosomes it has been shown that bulinus truncatus is predominant in the study area. bulinus globosus is scarcely encountered. biomphalaria pfeifferi is only found in the mayo guerleo, in irrigation canals and draining ditches. but b. globosus and b. pfeifferi have not yet invaded the recent aquatic network and are not found in the lake nor in the newly created irrigatio ...19827201892
analysis and preliminary purification of glycoproteins isolated from eggs in the urine of patients with schistosoma haematobium infection.preliminary analysis and purification of glycoproteins from schistosoma haematobium eggs were carried out with a small quantity of antigenic material obtained from the urine of infected human patients. a soluble egg extract was 125i-labeled and was fractionated by lectin affinity chromatography for separating egg glycoproteins. the crude glycoprotein fraction was run on sds-page to yield three polydisperse peaks with rf values of 0.31, 0.57, and 0.84. 125i-labeled egg glycoproteins were further ...19827202027
schistosoma haematobium and the nephrotic syndrome.two boys with nephrotic syndrome, membrano-proliferative glomerulo-nephritis and schistosoma haematobium infection are described. both showed remission of the nephrotic syndrome soon after the schistosomiasis was treated with niridazole. the significance of heavy proteinuria in schistosomiasis is discussed.19807210112
single dose use of metrifonate. 19807210121
immunization of baboons (papio anubis) against schistosoma haematobium with irradiated cercariae or schistosomula. 19807210146
assessment of immediate and delayed hypersensitivity skin tests with schistosoma mansoni adult worm antigen in a rural egyptian population.immediate and delayed hypersensitivity responses to schistosome adult worm skin test antigen were assessed in 418 farmers in dakahlia governorate, egypt. all were from a population frame being epidemiologically evaluated for bilharzial urinary bladder cancer and thus were all 20 years old or older. a control, group of 108 adult urban dwellers without antecedent or current history of schistosomiasis were also tested. ninety eight percent (411/418) of farmers and 35% (38/108) of controls showed re ...19807210159
the circumoval precipitin test for the serodiagnosis of human schistosomiasis mansoni and haematobia. 19817212158
changes in the tegumental surface of schistosoma haematobium during development in the mammalian host.the development of surface of schistosoma haematobium in the mammalian host was studied by scanning electron microscopy, beginning with lung stages obtained at 7 days, and at various intervals thereafter to completion of development. the major changes observed were similar to those previously seen in schistosoma mansoni.19817212159
use of metrifonate for selective population chemotherapy against urinary schistosomiasis in an endemic area at mwanza, tanzania. 19817215272
existence of replicating sporocysts in the development cycle of schistosoma haematobium. 19807218107
schistosoma haematobium ova in semen. 19817218473
[monitoring the treatment of s. haematobium schistosomiasis by rectal biopsy]. 19817220342
schistosoma bovis, s. intercalatum and s. haematobium: methods for in vivo radiolabelling of cercariae with radioselenium.cercariae of schistosoma bovis, s. intercalatum and s. haematobium were radiolabelled by individual exposure of their respective host snails to 75se-methionine in 1 ml water for a period of 20 hours. maximum cercaria-bound radioactivity was obtained four to seven days after labelling of snails, but detectable levels of radioactivity incorporation were obtained with all three species for a period of 32 days. the radiolabelling procedure did not interfere with the production of cercariae or with t ...19817229335
the effects of schistosomiasis on spontaneous play activity in black schoolchildren in the endemic areas. an ethological study.an ethological study was undertaken in two primary schools in natal to assess the effect of schistosome infections on the spontaneous activity of schoolchildren in endemic areas. results indicate that there is selective exposure of more active children to the disease. in low-level infections with schistosoma haematobium (less than 1000 eggs excreted in a 2-hour midday period) or s. mansoni (less than 1000 eggs/g dry weight of stool) there is little evidence of a decrease in energetic activity un ...19817244929
a note on the prevalence of schistosoma haematobium and s. mansoni in kindu and kasongo, kivu area, zaire. 19817247518
[oltipraz in one-day treatment of schistosoma haematobium bilharziasis (pharmacokinetic data, therapeutic effects)]. 19817256027
bladder calcification and obstructive uropathy in a gibbon infected with schistosoma haematobium.a gibbon was repeatedly exposed to schistosoma haematobium infection and was followed for 68 months after the first exposure. severe obstructive uropathy and calcification of the bladder and ureters were found despite the fact that mean excretion of eggs in the urine averaged 167 eggs per day and never exceeded 400 eggs per day.19817258481
a longitudinal study of schistosoma haematobium infection in qena governorate, upper egypt. 1. initial epidemiological findings.an epidemiological study was conducted as an initial phase of a longitudinal study on the immunology of schistosoma haematobium in upper egypt. the study area was confined to three villages in qena governorate, a region endemic solely for s. haematobium. in a cross-sectional survey in two of these villages, the overall prevalence of infection was 28.7% (29.9% at khozam and 26.9% at el ayaisha) based on urine examination of the family members in every third household. s. haematobium infection was ...19817258491
parasitological characters as tools in the taxonomy of the intermediate snail hosts for schistosoma spp. 19807267153
[case of schistosoma haematobium invasion]. 19817269585
prevalence of schistosoma haematobium in the koryole and merca districts of the somali democratic republic. 19817271355
studies on the transmission of schistosoma haematobium and the bionomics of bulinus (ph.) abyssinicus in the somali democratic republic. 19817271356
[schistosomiasis in the people's republic of mozambique]. 19817278812
[cultivation of mollusks, the intermediate hosts of schistosomes (a review of the literature)]. 19817278814
schistosoma haematobium in ajara community of badagry. metrifonate trials in the treatment of the disease.metrifonate, an organophosphorus cholinesterase inhibitor, which has been shown to be effective in the treatment of urinary schistosomiasis was administered orally to 145 school children aged 6-15 years at a dose of 10 mg/kg body weight in 3 doses at 14-day intervals. urinalysis was carried out to determine egg out-put, haematuria and proteinuria. none of the subjects was anaemic before treatment, 78.6% tolerated the drug well while 21.4% had minimal and transient side-effects. 47.6% with light ...19817281216
distribution in kenya of intermediate hosts of schistosoma.a major factor in the geographical distribution of endemic schistosomiasis in kenya is the discontinuous distribution of intermediate hosts. biomphalaria pfeifferi is the main transmitter of s. mansoni and is found in the altitude zone 300-2,300 m; its absence from the costal region results in the absence of endemic schistosomiasis mansoni amongst the large human population in the coastal region. snails belonging to the bulinus africanus group appear to be responsible for all transmission of s. ...19817281220
igg4 antibodies in egyptian patients with schistosomiasis.serum immunoglobulins were determined in 40 egyptian patients with schistosomiasis. in addition to the well-established elevation in total ige, a striking imbalance in the igg subclass levels was found: igg3 and igg4 levels were markedly elevated, whereas igg2 levels were normal. the igg4 level did not correlate with the igg3 level, but a weak correlation between the igg4 levels and the logarithmic value of the ige levels was observed (r = 0.49). we determined anti-schistosome antibodies in the ...19817287200
schistosomal nephrotic syndrome. 19817292600
morbidity studies of schistosomiasis hematobia in egyptian adults (preliminary report). 19817299183
cell-mediated immune assay in children with schistosoma haematobium infection and the effect of niridazole therapy.forty-five children with schistosoma haematobium infections were studied utilizing a whole-blood culture technique to assay lymphocyte blast transformation responses. the mitogenic lectins, phytohaemagglutinin (pha) and pokeweek mitogen (pwm), and heterologous schistosomal antigens from adult worms and eggs were used. responsiveness to pha was intact but pwm responses were significantly impaired. varying responses to schistosomal adult worm antigens were evident. responses to soluble egg antigen ...19817303134
a miracidium trap for use in flowing water. 19817305509
urinary schistosomiasis in egyptian farmers treated with metrifonate (bilarcil). 19817305511
disruption of bilharzia transmission in the kortume flood plain of the awash valley, ethiopia. 19817308180
[epidemiological studies, with the direct and immunodiagnostic method, of parasitic diseases in residents of a somalia village located in the irrigated zones].the authors carried out an epidemiological survey for the evaluation of the incidence of the parasitoses in a somali village localized in proximity to a watercourse. they found parasites in the 72,53% of the examined population: schistosoma haematobium 42.5%, ascaris lumbricoides 32%, ancylostoma duodenale 14%, entamoeba histolytica 7,5%. the immunofluorescence, nevertheless, showed the presence of antiparasite antibodies in a much higher percentages of cases; it could meant that the real incide ...19807312395
studies on schistosomiasis in village gimvi of maharashtra. 19817319572
a note on drug trials in schistosomiasis.in schistosomiasis, if the subjects of drug trials are in contact with potentially contaminated water, then differences in the chemotherapeutic response to the same dose of a drug given in the same endemic area in different seasons, may be related to different levels of transmission. because a reduction in egg excretion may occur from causes other than chemotherapy, moderate antischistosomal activity of a drug cannot be concluded in the absence of a control group.19817324139
a preliminary survey of malnutrition and helminthiasis among schoolchildren in one mountain and one lowland ujamaa village in northern tanzania.the nutritional status, parasite prevalence and immediate skin hypersensitivity to ascaris and schistosoma antigens were determined for 185 schoolchildren living in two ujamaa villages in northern tanzania. in the lowland village of kwamsisi the parasite ova found were schistosoma haematobium (53.8%), ascaris (26.0%) and hookworm (24.7%). 57.5% of the children examined were regarded as malnourished, being less than 80% of their expected weight for age. in the mountain village of ubiri the parasi ...19817330928
comparison of whole blood cultures and peripheral blood mononuclear cell cultures for evaluation of lymphocyte reactivity during chronic schistosomiasis.lymphocyte blastogenesis during chronic schistosomiasis has been evaluated previously by either whole blood or peripheral blood mononuclear cell (pbmn) culture techniques. these two methods were compared in the present study. blastogenesis to the mitogen phytohaemagglutinin was greater in the whole blood cultures at the time assayed. substantial antigen-induced lymphocyte transformation was elicited in both culture systems using cells from uninfected patients. however, patients' responses to sch ...19817330939
an epidemiological study of schistosoma haematobium and s. mansoni infection in thirty-five rural egyptian villages.probability samples of individuals from 35 village communities in the rural egyptian nile valley were examined for the presence of schistosome ova by sedimentation of urine and by the mifc technique for stools. in all there were 12,933 persons selected of which 11,337 provided specimens for examination from a total population of 66,768 persons divided among three governorates: 37% in north central delta, 31% in upper-middle egypt and 32% in the upper egypt. after controlling the differences attr ...19817342382
[general review of the clinical results obtained with biltricide in the treatment of human schistosomiasis (author's transl)]. 19817343126
therapeutic properties of metrifonate.the chronology of the clinical trials with metrifonate is described: the first phase where independently of bayer use was made of the veterinary product, the second phase representing the work done in collaboration with who to confirm the correct indication (schistosomiasis due to s. haematobium) and dosage schedule, and the third phase as from 1970 on about the use of the product in large groups of patients. the particular aspects of schistosomiasis are discussed, as well as the place of chemot ...19817344404
metrifonate in schistosomiasis - therapy and prophylaxis.the introduction and development of the organophosphorous drug metrifonate, first as an insecticide and then for the treatment of urinary schistosomiasis, has followed an unusual course. in its most widely accepted treatment regimen it is safe, effective and apparently without significant side effects. these facts, together with its low cost and ease of dosing, lead to a field trial of its efficacy in the treatment and prevention of infection in children in an area of high s. haematobium and s. ...19817344406
esterases in schistosomes: reaction with substrates and inhibitors.studies were made (at 37 degrees, ph 7.6) on the interaction of some organophosphorus compounds and carboxylic acid esters with cholinesterases (ec 3.1.1.7 and ec 3.1.1.8) and a-esterases (ec 3.1.1.2) in homogenates of schistosoma mansoni (adults and cercariae) and schistosoma haematobium (adults). the results are compared with those obtained from the same reactions in other parasitic helminths and in mammalian tissues. metrifonate (0,0-dimethyl-2,2,2-trichloro-1-hydroxyethyl phosphonate) does n ...19817344415
levels of metrifonate and dichlorvos in plasma and erythrocytes during treatment of schistosomiasis with bilarcil.a method for the simultaneous quantitation of metrifonate (0,0-dimethyl-(1-hydroxy-2,2,2-trichloroethyl)-phosphonate) and dichlorvos (2,2-dichlorovinyl dimethyl phosphate, ddvp) in human blood has been worked out. it is based upon multiple labelling of the compounds with deuterium and gas phase analysis using the mass spectrometer as a selective detector. the amount of ddvp in plasma is about 1% of the amount of metrifonate. in erythrocytes the corresponding amount of ddvp is 0.5% or less of met ...19817344416
schistosoma weinland, 1858 from hippopotamus amphibius linnaeus, 1758 in the kruger national park.adults of schistosoma edwardiense thurston, 1964, were recovered from hippopotamus amphibius in the kruger national park. small round to oval schistosoma margrebowiei-like eggs, presumed to be those of s. edwardiense, were found fairly frequently in the faeces of infected hippopotami together with a few schistosoma haematobium-like eggs the identity of which remains uncertain. biomphalaria sp., exposed to the droppings of infected hippopotami, shed cercariae thought to be those of s. edwardiense ...19817345384
modulation of in vitro lymphocyte proliferation in patients with schistosomiasis haematobium, schistosomiasis mansoni and mixed infections.cell-mediated immunity to mitogens, nonparasitic and parasitic antigens was evaluated by means of in vitro lymphocyte proliferation in 37 african patients infected with s. haematobium, s. mansoni, or both parasites as well as in an uninfected control group. lymphocytes of patients with schistosomiasis mansoni or schistosomiasis haematobium monoinfection could be similarly stimulated by a delipidized extract of s. mansoni adults. there was also no difference in lymphocyte responsiveness to stimul ...19817345689
schistosomal infections in some primary schools in kabwe rural district. 19817347471
bilharziasis of the urinary tract in zambia. (observation on 100 consecutive cases).cystoscopic, urographic and histological observations on 100 consecutive cases of urinary bilharziasis are presented. 35 patients had calcification of the urinary tract whilst i.v.u. of 40 patients were abnormal. abnormal urograms were more often observed in patients with reduced bladder capacity than with vesical calcification. surgery to the urinary tract was considered necessary in 19 patients. there were 3 deaths and all were secondary to schistosomiasis. our observations indicate that urina ...19817347476
[analysis of secretory iga in the urine of patients schistosoma haematobium schistosomiasis]. 19817348802
[urinary bilharziasis in spain (a case in león)].the authors draw attention to the potential danger of urinary schistosomiasis in spain, pointing out the nuclei in the country which present snails suitable for being intermediary carriers. they present one case, not autochthonous, observed in león and they point out the possible increase in this parasitosis, due to the increase in immigration and tourism, with the possible infesting of the aboriginal snails and the resulting formation of endemic areas in the said nuclei. in view of the precario ...19807362280
[distribution of schistosomiasis in french speaking countries of west africa (author's transl)].after reporting an abstract of the surveys prior to 1969, the authors recall their methodology and give the data collected during the surveys carried out since 1969 by the o.c.c.g.e. in 23 districts of 7 west african countries. -urinary schistosomiasis is widespread but the highest endemic levels are observed in the sahel area. - s. mansoni schistosomiasis, on the contrary, has a more restricted area of diffusion. it is frequent in sudanese and guinean savanna and does not affect the sahel and t ...19807366364
[study of the distribution of schistosomiasis mollusks intermediate hosts in west africa. first results (author's transl)].during 18 surveys carried out in 29 regions of 6 west african countries (benin, ivory coast, upper volta, mali, niger and togo), one species of biomphalaria (biomphalaria pfeifferi) and six species of bulinus (bulinus truncatus rohlfsi, b. globosus, b. jousseaumei, b. umbilicatus, b. senegalensis and b. forskalii) were collected. first indications of the distribution of these species demonstrated: the presence of 3 principal species (b. pfeifferi, b. globosus and b. truncatus rohlfsi); the absen ...19807366365
[hepatosplenic disorders in schistosomiasis (author's transl)].hepatosplenic disorders start in the invasion stage and are from immuno-allergic origin. then, they develop during the ovular laying stage; hepatic disorders are due to periovular granulomatosis, and splenic disorders are due to reticulo-endothelial system reaction. their last aspect is the portal fibrosis, called symmer's "clay pipe", in which htp is consequent to hepatic disorder and the main cause of splenomegaly. the location of s. japonicum and s. mansoni in pericolic veins explains that he ...19807366366
[glomerular nephropathy and schistosomiasis (author's transl)].glomerular lesion appears frequently in patients with s. mansoni or s. japonicum infection. this nephropathy may bring clinical changes and leads to severe evolution with letal risk. it may be induced or aggravated by the specific treatment but it has then, in most cases, a short duration and a good prognosis. specific treatment fixed in order to reduce the amount of circulating antigens may be benefic. in some cases, on the contrary, the nephropathy is not reactive to any specific or symptomati ...19807366367
[anatomopathological aspects of schistosomiasis. a study of 286 pathological specimens. (author's transl)].schistosomiasis pathology demonstrates the successive stages of the specific inflammation and accounts for the large variety of its macroscopic and histological features. this paper reviews 286 bilharzial lesions studied between 1956 and 1979 at the ""institut de médecine tropicale du service de santé des armées". - first, the histopathological caracteristics of the disease are considered. some lesions are caused by schistosomules and adult worms, but the proeminent role is devoted to egg: the b ...19807366368
serum and urinary amino acid pattern in schistosomal infection among egyptians.the amino acid pattern in plasma and urine of bilharzial egyptian patients with different degrees of complications was investigated. the results obtained showed that in mansoniasis, accumulation of amino acids in the circulation is due to derangement in liver function which retards the utilization of amino acids in protein synthesis particularly in the advanced stage of the disease. this is also in part due to liver cell degeneration which parallel the severity of the infection. aminoaciduria in ...19807376258
schistosoma haematobium infection in the white mouse--histopathological and histochemical studies.mice were infected with 1000 schistosoma haematobium cercariae (egyptian strain). histopathological and histochemical studies were performed on the different organs, during the first four weeks after infection and on the fourth week after oviposition. pathological changes during early prepatency matched with those in s. mansoni infection. eggs were laid in aggregates in the colon and liver. they initiated the development of typical granulomatous lesions. abundant bilharzial pigment and areas of ...19807377626
evaluation of schistosomal morbidity in subjects with high intensity infections in qalyub, egypt. 19807386720
plasma levels of metrifonate and dichlorvos during treatment of schistosomiasis with bilarcil.metrifonate (0,0-dimethyl-[1-hydroxy-2,2,2-trichloroethyl]-phosphonate), and its rearrangement product dichlorvos (2,2-dichlorovinyl dimethyl phosphate) (ddvp), were studied in plasma from two patients with schistosomiasis who were treated with bilarcil. a mass fragmentographic technique was used. isotopic variants of the substances were used as internal standards and to compensate for ddvp formed during the workup procedure. the results were related to erythrocyte and plasmacholinesterase deter ...19807386721
non-endemic schistosomiasis in south australia. 19807393043
[african schistosomiasis at the invasion stage. criteria for diagnosis. control after 5 years (author's transl)].the authors expose their conclusions after controlling 181 young soldiers affected by schistosomiasis in an epidemic having occured in tchad en 1973-74, none of them having been later on submitted to parasitic infection: --relative value of classical diagnosis criteria (50 p. 100); --reliability of immunologic symptoms; -- frequency, importance and precocity of specific granulomatous hepatic changes, detected by laparoscopie and biopsy (87,2 p. 100 of the cases). the value of niridazole is confi ...19807402061
[medical treatment of schistosomiasis (author's transl)].after a brief reassessment of the pathogenic problem, the authors review the presently available drugs and their respective dosage and side-effects. then they consider each of the four parasitological types of schistosomiasis and indicate the most active treatment.19807402062
[pulmonary symptoms in schistosomiasis (author's transl)]. 19807402063
[schistosomiasis of vulvae (case report and comments) (author's transl)].report of a case observed in malagasy republic, caused by schistosoma haematobium and associated with a urinary envolvement. a niridazol treatment lead to rapid recovery. pathogenic processes of this localization are reviewed with regard to venous anatomy and parasitologic features. venereal diseases, tuberculosis and cancer are the main affections capable to lead to mistaking. pathology is a necessary and reliable control. treatment is easy with niridazol or, in case of failure, with the variou ...19807402067
study of bilharzial uropathy by means of hippuran i131 extended renography.renal, ureteral, and vesicle functions were evaluated in 209 patients with obstructive lesions of the ureter due to schistosomiasis haematobia (bilharziasis), using hippuran i131 extended renography. high values for tmax. and t 1/2 were noted for both kidneys irrespective of radiological diagnosis of a left- or right-sided lesion. a high percentage of residual vesicle urine was demonstrated in a number of patients with bilharzial uro-obstructive lesions. the incidence of vesicoureteral reflux in ...19807406107
a study on the etiological factors of bilharzial bladder cancer in egypt: 5-urinary nitrite in a rural population.urinary nitrite was present in 5.6% of 2379 individuals from a rural population infested with "schistosoma haematobium". a higher frequency was observed in symptomatic patients with active bilharzial cystitis (25%) and patients with bladder cancer associated with schistosomiasis (66.2%); conversely, urinary nitrite was absent in normal urban individuals. the frequency of urinary nitrite was higher in females (6.4%) than males (4.6%), and was more frequent in adults than extremes of age. the pres ...19807414706
hybrids between schistosoma haematobium and s. mattheei and their identification by isoelectric focusing of enzymes.some biological features of f1 hybrids between south african strains of schistosoma haematobium and s. mattheei are described and compared with those of both parental species. the distinctive patterns of the g6pd and pgm isoenzymes, resolved by isoelectric focusing, of both species and of the hybrid are defined and the results of enzyme analyses of parasites isolated from human infections in the transvaal are reported. these show that hybridization does occur naturally in man and that the shape ...19807434427
urinary schistosomiasis: its altering geographical pathology. 19807443628
urethritis due to schistosoma haematobium with superimposed gonorrhea.a case of urethritis due to schistosoma haematobium with superimposed gonorrhea is described. the diagnosis was confirmed by the presence of gram-negative intracellular diplococci in the urethral discharge and of characteristic terminal spined schistosoma haematobium ova in the urine, as well as by the favorable clinical response to treatment with the antischistosomal drug niridazole. a diagnosis of schistosomiasis should be considered for patients in whom treatment with drugs that are active ag ...19807444712
comparative karyology of the freshwater snails bulinus tropicus and b. natalensis.species of the subgenus bulinus s.s. occur in a polyploid series which is of interest because of the rarity of polyploidy in animal species and because there appears to be a relation between ploidy level and ability to transmit schistosoma haematobium, a parasite of major public health importance. we describe a technique for the preparation of standard karyotypes using cell suspensions from colchicine-treated embryos. the results for two diploid species, b. tropicus (krauss) and b. natalensis (k ...19807448622
clinical development of oxamniquine in egypt. 19807455504
impact of development on the spread of schistosomiasis in egypt. 19807455510
goals of applied chemotherapeutic research in schistosomiasis. 19807455513
malumfashi endemic diseases research project, xv. the potential medical importance of bilharzia in northern nigeria: a suggested rapid, cheap and effective solution for control of schistosoma haematobium infection. 19807458464
effect of schistosoma haematobium and n-butyl-n-(4-hydroxybutyl)nitrosamine on the development of urothelial neoplasia in the baboon. 19807459210
schistosoma mansoni and schistosoma haematobium: difference in development. 19817461088
the effects of a soluble factor released by sensitized mononuclear cells incubated with s. haematobium ova on eosinophil migration.incubation of sensitized mononuclear cells from patients with schistosomiasis with specific antigen containing a suspension of viable schistosoma haematobium ova resulted in the release of a soluble factor which was chemotactic for eosinophils. production of this substance was detectable at 24 h and demonstrated peak chemotactic activity after 2 days in culture. the chemotactic potential was dose-dependent and attracted eosinophils obtained from patients with schistosomiasis or allergic diathesi ...19807461720
[presence of schistosoma haematobium eggs in an ovarian teratoma]. 19807469543
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