| size and density characterization of human committed and multipotent hematopoietic progenitors. | physical characterization of human blood and bone marrow (bm) hematopoietic precursors is necessary for the design of adequate techniques to isolate these cells for experimental and possible clinical use. elutriation and continuous percoll gradient were used to define the size and density of committed (cfu-gm, bfu-e, and cfu-e) and multipotent (cfu-mix) progenitors on paired bm and blood samples from normal donors. cells were initially prepared over ficoll-hypaque (specific gravity 1.077 g/cm3). ... | 1985 | 4029293 |
| correlation of plasmid type and disease caused by coxiella burnetii. | the obligate intracellular bacterium coxiella burnetii is the etiological agent of acute q-fever and chronic endocarditis in humans and of several zoonotic infections. the dna from a variety of these disease isolates was compared for homology to the plasmid qph1, found in the nine mile strain. three patterns of homology were found in these isolates, i.e., one pattern identical to that of qph1, one common to several endocarditis isolates and goat abortion isolates, and one common to the remaining ... | 1985 | 4030104 |
| coxiella burnetii infection in immunocompromised patients. | | 1985 | 4031524 |
| pneumonia and meningo-encephalitis due to coxiella burnetii. | we describe the case of a 35-year-old man who presented with pneumonia and encephalitis due to coxiella burnetii. the neurological manifestations of q fever are discussed and we suggest that c. burnetii be included in the differential diagnosis of patients with pneumonia and encephalitis. | 1985 | 4031527 |
| inhibition of fatty acid synthesis in rabbit mammary alveolar explants by progesterone and related steroids. | the possible inhibitory effect of steroids related to progesterone on prolactin-stimulated fatty acid synthesis in mammary alveolar explants from 11-day pseudopregnant rabbits, after culture, was investigated. like progesterone, 17 alpha-hydroxyprogesterone, 20 alpha-dihydroprogesterone, medroxyprogesterone acetate, ethinodiol diacetate, org 2058 were inhibitory whereas pregnenolone and 5 alpha-pregnan-3,20-dione were not. | 1985 | 4033116 |
| [effect of biotic factors on the infectivity of ixodid ticks with coxiella burnetii. 1. the significance of the period of tick feeding for the outcome of infection]. | | 1985 | 4033542 |
| nature and linkage type of fatty acids present in lipopolysaccharides of phase i and ii coxiella burnetii. | the constituent fatty acids of lipopolysaccharides (lps) of coxiella burnetii (phase i and ii) were qualitatively and quantitatively analysed by combined gas-liquid chromatography/mass spectrometry. the total fatty acid content (per mg lps) was determined as 90.0 nmol (2.3 wt%) for lps of phase i cells (lps i) and 179.1 nmol (4.8 wt%) for lps of phase ii cells (lps ii). of the 24 different acyl residues characterized (12 to 18 carbon atoms), nine were 3-hydroxy fatty acids (normal, iso- and ante ... | 1985 | 4037979 |
| effect of nonsteroidal anti-inflammatory drugs on the microsomal monooxygenase system of rat liver. | the effect of acetylsalicylic acid, ibuprofen, indomethacin, ketoprofen, naproxen, phenylbutazone, and salicylic acid on the microsomal oxidative drug metabolism of rat liver was studied. pretreatment of the rats with pharmacologic doses of acetylsalicylic acid, indomethacin, and ketoprofen decreased both the demethylase and hydroxylase activities of rat liver microsomes. these effects were paralleled by decreases in microsomal cytochrome p-450 content. the rate of the microsomal reactions was i ... | 1985 | 4042014 |
| variation in responsiveness of balb/c sublines and congenic mice to phase i coxiella burnetii infection and vaccination. | | 1985 | 4042676 |
| [action of antiviral substances on influenza viruses through the inhibition of neuraminidase production]. | | 1985 | 4051653 |
| the importance of coxiella burnetii as a cause of pneumonia in nova scotia. | | 1985 | 4052906 |
| [role of irritant receptors in shortening expiration during collapse of the lungs]. | in 24 vagotomized cats, firing rate of 44 irritant receptors was studied in lung collapse under conditions of pneumothorax or sucking off of air. the firing rate increased in 26 receptors in the latter condition. in pneumothorax the firing rate increased 1.5-2.7-fold as compared with sucking off of air. discharges of the lung stretch receptors are practically similar in both conditions but the expiration increases more in pneumothorax due to a more intense activation of the irritant receptors. t ... | 1985 | 4054398 |
| shedding of coxiella burnetii in milk by nigerian dairy and dual purposes cows. | fresh milk from dairy cows kept at semi-intensive husbandry in governmental and institutional farms and dual purpose fulani nomadic husbandry around zaria, nigeria were screened for coxiella burnetii using the mouse inoculation test. of the 20 herds from both management systems tested, 16(80.0%) contained dairy cows shedding c. burnetii in their milk. of a total of 169 cows tested, 41(24.3%) were shedders. eighteen (22.0%) of 82 cows kept under semi-intensive and 23(26.4%) of 87 cows kept under ... | 1985 | 4055266 |
| local toxicity of different drugs after intramuscular or intralipomatous injection in pigs: serum concentrations after three different formulations of cis(z)-clopenthixol. | findings made by computerized tomography scanning of pelvis of patients suggested that the majority of injections intended to be intramuscular in fact are delivered in the fat tissue. this finding has raised the question what difference it makes when drugs are injected intramuscularly or intralipomatously. we have studied local toxicity after intramuscular or intralipomatous injection of different drugs in pigs, which have a subcutaneous layer of fat comparable to that of man. the pigs were kill ... | 1985 | 4061093 |
| analysis of the genome of influenza a virus strains (h3n2) isolated during the epidemic season of 1982-1983. | the crna:vrna hybridization technique was used to analyse h3n2 influenza virus isolates obtained from influenza patients in the united kingdom and the u.s.a. (alaska) during the epidemic season of 1982-1983. the majority of isolates differed from reference h3n2 influenza virus strains a/bangkok/1/79 and a/philippines/2/82 as well as from one another in the homology of nearly all the genes. no identical strains were detected among the isolates including the ones isolated in the same town and at t ... | 1985 | 4062561 |
| age-associated alterations in hepatic glutathione-s-transferase activities. | age-associated alterations of hepatic cytosolic glutathione-s-transferase (gst) activities towards sulfobromophthalein sodium tetrahydrate (bsp), styrene oxide (stox), trans-4-phenyl-3-butene-2-one (pbo), 1,2-dichloro-4-nitrobenzene (dcnb), and 1-chloro-2,4-dinitrobenzene (cdnb) were investigated in fischer-344 rats of both sexes with ages ranging from 1.5 to 28 months. the gst activities towards pbo and dcnb in male rats increased with age till 6-12 months when maximum values were attained, and ... | 1985 | 4062964 |
| q-fever endocarditis. | | 1985 | 4063935 |
| avulsions of the auricle. | | 1985 | 4064990 |
| [cau--an accessory device for automatic monitoring and evaluation of fixation with the computer perimeter competer]. | during perimetry with the "competer" fixation is tested by random switching of a projector lamp which has to be directed manually into the individual blind spot before the test is started. in order to improve efficiency with regard to time required, acceptance, and validity of the test, a device has been designed which rapidly locates the center of the blind spot and verifies it by random checks. both the test logic and the design and operating features of this device, which works independently ... | 1985 | 4068599 |
| viral and rickettsial etiology of an outbreak of acute respiratory tract infection. | an outbreak of 111 cases of acute respiratory tract infection was recorded in a community of the town "t" in april-may 1984. the clinical picture was severer than usual; 28% of the cases had to be hospitalized, average absenteeism being as high as 26 days per case. serological investigations demonstrated the previous circulation of influenza virus b/singapore/222/79 and the simultaneous circulation during the outbreak of influenza virus a/england/333/80 (h1n1) and of rickettsia burneti (as also ... | 1985 | 4071978 |
| enzyme immunoassay for surveillance of q fever. | an enzyme-linked immunosorbent assay (elisa) was developed to monitor antibodies against coxiella burnetii among animal populations used in research and teaching facilities. various antigenic components of c burnetii prepared from phase i and phase ii whole cells and commercially available antigens were evaluated. a trichloroacetic acid extract was selected for routine use. there was a linear relationship between the transformed absorbance readings of the elisa results and microagglutination (ma ... | 1985 | 4073655 |
| growth of crypt cell nodules in duodenal mucosa in man during organ culture in vitro. | culture of peroral biopsy specimens from duodenal mucosa in vitro for 22 hours using a basic culture medium resulted in the formation of crypt cell nodules. the addition of collagen and serotonin to the culture medium increased the occurrence of the nodules and, invariably, their size. the nodules were situated on the pericryptal basement membrane and contained cells that resembled columnar cells, goblet cells, and endocrine cells. the overall nodular structure suggested that they had been forme ... | 1985 | 4078020 |
| subclinical chronic q fever. | seven patients are described in whom chronic q fever was detected by serology (coxiella burneti phase i antibody titre greater than 1:200) during routine screening at admission for cardiac catheterisation. none had clinical evidence of endocarditis, hepatitis or other foci of infection. three of the patients were kept under observation without antibiotic treatment for periods of six, 18 and 20 months. in two patients of this group, cardiac tissue was obtained at operation and in one patient sero ... | 1985 | 4080956 |
| [imported leather raw materials as a cause of q fever]. | | 1985 | 4081076 |
| [coxiella burnetii as a possible cause of endocarditis in a 7-year old boy]. | the case-history of a 7-year-old boy with endocarditis, myocarditis and pericarditis, possibly caused by coxiella burnetii (q-fever), is presented. as far as we know only one case of q-fever endocarditis in a child is previously described in literature. that child had, contrary to our patient, a pre-existing valve abnormality. q-fever was diagnosed after demonstration of a significant rise in titer of the antibodies against coxiella burnetii in both the igm and the igg fractions. iga antibodies, ... | 1985 | 4082171 |
| the first human case of domestic q fever in sweden. | a case of q fever in a 56-year-old man is reported. the patient had visited mallorca six months prior to the present disease. except for that he had not been outside sweden for several years, thus being the first known case of q fever acquired in this country. | 1985 | 4083085 |
| the use of a single complement fixation test technique in bovine brucellosis, johne's disease, dourine, equine piroplasmosis and q fever serology. | the same techniques may be used in the complement fixation test (cft) for the serological diagnosis of bovine brucellosis, johne's disease (paratuberculosis), dourine, equine piroplasmosis and q fever (caused by coxiella burnetii). the reproducibility of results is excellent, falling for the most part within the twofold range and never exceeding the fourfold range. agreement with other laboratories is excellent (i.e. within twofold) in the case of brucellosis and equine piroplasmosis antibody ti ... | 1985 | 4088642 |
| [reappearance of q fever (rickettsiosis caused by coxiella burnetii) in cattle in the canton of vaud]. | | 1985 | 4089590 |
| [epidemiologic field study of q-fever]. | | 1985 | 4089683 |
| systemic tetracyclines in the treatment of noninfected corneal ulcers: a case report and proposed new mechanism of action. | corneal melting refers to a condition in patients whose corneas undergo progressive necrosis of stromal tissue despite being culture negative. recent evidence has shown that systemic tetracyclines demonstrate anti-collagenolytic activity that may have clinical effectiveness in disease treatment. the evidence led us to try this modality as adjunct therapy in the treatment of an 80-year-old white man with a noninfected corneal ulcer. one gram of tetracycline in four divided doses led to a dramatic ... | 1985 | 4091374 |
| metabolism of paeoniflorin and related compounds by human intestinal bacteria. | | 1985 | 4092282 |
| an equation for ligand binding to protein over a wide range of ligand concentration. | | 1985 | 4092296 |
| electron microscopic studies of lipopolysaccharides from phase i and phase ii coxiella burnetii. | lipopolysaccharides from phase i (lpsi) coxiella burnetii ohio and nine mile strains and from phase ii (lpsii) nine mile stain were negatively and positively and examined with the electron microscope. the ultrastructure of lpsi and lpsii positively stained with uranyl formate or uranyl acetate was ribbon-like. when negatively stained with uranyl acetate, lpsi was ribbon-like but lpsii exhibited hexagonal lattice structures. however, lpsii stained negatively with sodium phosphotungstate and ammon ... | 1985 | 4093765 |
| q fever in north-east scotland. | | 1970 | 4098056 |
| electron microscopy of coxiella burneti phase i antigen. | | 1970 | 4098185 |
| electron microscopic studies of the rickettsia coxiella burneti: entry, lysosomal response, and fate of rickettsial dna in l-cells. | | 1971 | 4100953 |
| structure of bacterial flagella from salmonella typhimurium: effects of hydration and some stains on the equatorial x-ray diffraction patterns of cast films. | | 1971 | 4102339 |
| the role of mucopolysaccharides in vesicle architecture and endothelial transport. an electron microscope study of myocardial blood vessels. | | 1972 | 4108322 |
| presence of ribosomal ribonucleic acid in the rickettsia coxiella burneti. | | 1971 | 4110461 |
| localization of coxiella burneti and rickettsiae of the rocky mountain spotted fever group in ticks. | | 1972 | 4110513 |
| marker band in one chromosome 14 from burkitt lymphomas. | | 1972 | 4113130 |
| the chemistry of allergens. xxi. eight new antigens generated by successive pepsin hydrolyses of bovine -lactoglobulin. | | 1972 | 4114295 |
| differentiation of phase i and phase ii coxiella burneti by means of fluorescent antibody techniques. | | 1972 | 4114474 |
| [attempt at localization of igg and igm rickettsia conori and rickettsia burneti antibodies in rabbits]. | | 1972 | 4118327 |
| electron microscopy of ruthenium red-stained phase i and ii coxiella burneti. | | 1972 | 4118527 |
| new faces of viral hepatitis. | | 1973 | 4118951 |
| testing in various systems of the neutralizing capacity of q fever immune sera. | | 1973 | 4119333 |
| the direct fluorescent antibody test for detection of brucella abortus in bovine abortion material. | the direct fluorescent antibody test was assessed for detection of brucella abortus in bovine abortion material. br. abortus organisms could be readily detected as characteristic intra-cellular clumps, in smears stained with fluorescent antibody. counterstaining with evans blue was necessary to suppress tissue auto-fluorescence. the method was specific and enabled brucella infection to be differentiated, inter alia, from q-fever infection. | 1973 | 4121013 |
| b cell mitogenic properties of thymus-independent antigens. | | 1973 | 4125593 |
| [blood and serum groups of foxes]. | | 1969 | 4128363 |
| [comparison of some methods of staining the flagella of phytopathogenic bacteria of the genera erwinia and pseudomonas]. | | 1972 | 4134018 |
| participation of baroreceptor reflexes in the perfused dog hind leg during electric stimulation of the hypothalamus. | | 1974 | 4135868 |
| binding capacity of (nh4)2so4-precipitate (25 percent-65 percent) of ph 5 enzyme of rat liver, after fasting and refeeding. | | 1974 | 4136560 |
| identification of different robertsonian translocations in man by quinacrine mustard fluorescence analysis. | | 1971 | 4142007 |
| further investigations on the fine structure of coxiella burneti. | | 1972 | 4146137 |
| comparison of antibody-binding and antibody-inducing capacities of phase i and phase ii coxiella burneti antigens. | | 1973 | 4150037 |
| perinatal drug metabolism and morphological changes in the hepatocytes of normal and phenobarbital-treated guinea pigs. | | 1974 | 4153895 |
| [preparation of q-fever antigen by frigen 113 extraction (author's transl)]. | | 1974 | 4156138 |
| effect of lysogenization on variability of phage type in rizobium meliloti. | | 1965 | 4159104 |
| [the intracellular distribution of catalase in two transplantable tumors of the rat]. | | 1967 | 4167320 |
| [obtaining and testing fluorescing corpuscular antigen from rickettsia burneti]. | | 1966 | 4177536 |
| effect of immunosuppressive therapy for renal transplantation in man on marrow and blood. | | 1968 | 4178180 |
| "hypothetical mean organisms" of mycobacteria. a study of the classification of mycobacteria. | | 1968 | 4179142 |
| immune globulins to coxiella burneti in man determined by radioisotope precipitation technic. | | 1969 | 4185865 |
| epidemic canine brucellosis due to a new species, brucella canis. | | 1969 | 4186949 |
| on the direct cortical connections of the neucleus centrum medianum thalami. | | 1969 | 4187634 |
| on the use of eosin as a fluorescent dye to demonstrate mucous cells and other structures in tissue sections. | | 1969 | 4189136 |
| suppression of igm and igg synthesis in young rabbits by 6-methyl mercaptopurine treatment. | | 1970 | 4193280 |
| hepatitis-associated antigen in chronic liver disease. | | 1970 | 4193331 |
| [the antigenic structure of rickettsia burneti phase i and ii by the method of electron microscopic immunocytochemistry]. | | 1970 | 4194415 |
| [the gas supply of hydrogen bacteria in submerged culture]. | | 1972 | 4196475 |
| plaque assay of rickettsiae in a mammalian cell line. | clear-cut and repeatable plaque assays were obtained for three rickettsiae of the spotted fever group (rickettsia rickettsi, r. conori, and r. montana) in vero cells used in a manner similar to that for arboviruses. in addition, three typhus group agents (r. typhi, r. canada, r. prowazeki) induced plaques in these cells. in preliminary tests coxiella burneti (nine mile strain) failed to produce plaques. comparable results were obtained in plastic flasks and plastic culture trays incubated in amb ... | 1974 | 4208640 |
| the phases of coxiella burneti and its immunosorbents. | | 1974 | 4214861 |
| [immunization of cattle against q fever]. | | 1974 | 4217487 |
| [q fever in the southern part of western slovakia]. | | 1974 | 4217494 |
| [experience in the virological detremination of q fever in kazkhstan]. | | 1963 | 4220694 |
| the chances of reducing the incidence of skin infections of the newborn in a maternity hospital. | | 1965 | 4221724 |
| [immunization of man with the live m-44 q-fever vaccine]. | | 1965 | 4225784 |
| urinary protein and carbohydrate. 3. age differences in acid mucopolysaccharides in human beings. | | 1967 | 4227464 |
| an arginine-dependent step in the maturation of type 2 adenovirus. | | 1967 | 4228867 |
| [some experience with the cultivation of coxiella burnetii in the tissue culture of a stable monkey kidney cell line]. | | 1967 | 4229750 |
| a serological survey of sera from domestic animals on easter island. | animals' sera collected on easter island from december 1964 to february 1965 were tested by appropriate methods for the presence of antibodies to various infections. these included, ornithosis, q-fever, brucellosis, johne's disease, leptospirosis, toxoplasmosis and vesicular stomatitis viruses. it appeared that the cattle and sheep were exposed to the ornithosis group of agents. the sheep were also exposed to toxoplasmosis. the low-grade reactions observed on the cattle sera with the leptospira ... | 1968 | 4233830 |
| study of protective antibodies in q fever vaccination. | | 1968 | 4234966 |
| [the epidemiologic characteristics of q fever in orenburg and the orenburg region]. | | 1969 | 4239993 |
| [dynamics of the build-up of complement fixing antibodies with antigens of rickettsia burneti phase i and ii isolated in azerbaijan]. | | 1968 | 4240249 |
| [on a mixed natural focus of q fever and tick-borne encephalitis in the eastern european south-taiga forests]. | | 1967 | 4240282 |
| [material on the distribution of q fever in udmurt assr]. | | 1967 | 4240531 |
| [use of a soluble antigen of rickettsia burneti as an allergen for retrospective diagnosis of q fever in children]. | | 1969 | 4243117 |
| studies on the structure of the mitochondrial membranes. | | 1970 | 4245917 |
| [importance of the bacterial surface of pathogenic staphylococcus]. | | 1969 | 4248671 |
| effect of atp on cysteine and other thiol-induced labilization of rat liver lysosomes. | | 1971 | 4257834 |
| nuclear magnetic resonance studies of heavy metal ion-sulfhydryl interactions in myosin. | | 1972 | 4263471 |
| membrane fluidity and membrane fusion. | | 1972 | 4266094 |
| characterization and specificity of proscillaridin antibodies. | | 1973 | 4272454 |
| [phospholipid composition of the sarcoplasmic reticulum of normal and denervated rabbit muscle tissue]. | | 1973 | 4273659 |
| model translocators for divalent and monovalent ion transport in phospholipid membranes. ii. the effects of ion translocator x-537a on the energy-conserving properties of mitochondrial membranes. | | 1974 | 4278782 |
| model translocators for divalent and monovalent ion transport in phospholipid membranes. ii. the effects of ion translocator x-537a on the energy-conserving properties of mitochondrial membranes. | | 1974 | 4278782 |
| [properties of protective antigen isolated from coxiella burneti (author's transl)]. | | 1974 | 4281352 |
| distribution of myocardial blood flow during cardiopulmonary bypass in normal and hypertrophied left ventricles. | | 1973 | 4282518 |
| the release of enzymes from escherichia coli by osmotic shock and during the formation of spheroplasts. | | 1965 | 4284300 |