| [characteristics of the enterobacteria strains isolated from the urine in urinary tract infections]. | study of biochemical properties of 421 strains of enterobacteria permitted to refer them to the following taxonomic groups of which e. coli constituted 83,4 +/- 3.6%, enterobactercloacae--97 +/- 3.0%, klebsiella 4.0 +/- 2.0%. enterobacter aerogenes, enterobacter hafnia, citrobacter, proteus rettgeri, proteus vulgaris were revealed in individual cases (0.2-1.0%). as a result of serological typing there were revealed 105 serological types of escherichia differing by 55 o-antigen variants, 26 h-ant ... | 1978 | 747014 |
| oxalate biosynthesis from phenylalanine by the providencia-proteus group organisms. | | 1978 | 747520 |
| [investigations on the antibacterial activity of fosfomycin on dst-agar (author's transl)]. | since in some european countries the activity of antimicrobial substances are assessed on disc-sensitivity-test (dst)-agar, routinely, it has been investigated whether and under which conditions fosfomycin might be tested on dst-agar with the agar-dilution and -diffusion technique. a total of 320 strains representing 7 species were used as teststrains, and mueller-hinton (mh)-agar was employed as reference medium. on dst-agar the mic-values were increased for some genera like klebsiella by a fac ... | 1978 | 749420 |
| ["klebsiellae" infections (author's transl)]. | results are presented on the frequency of klebsiellae recovery from biologic materials (urines, pleura or peritoneal exudates, cerebrospinal fluids, blood specimens) examined during one year. tobramycin was the antibiotic with the highest in vitro activity against the isolates. | 1978 | 753136 |
| the air meniscus as a radiographic finding: a review of the literature and presentation of nine unusual cases. | in addition to echinococcal cysts and mycetomas, a wide variety of disorders can occasionally produce an air meniscus sign on a chest radiograph. a proposed classification follows: i. infections a. lung abscess (with or without pulmonary gangrene) b. fungus ball c. bacterial ball d. tuberculoma e. blood clot in tuberculous cavity, rasmussen aneurysm f. echinococcal lung cyst ii. neoplastic a. bronchogenic carcinoma b. primary lung sarcoma c. metastatic carcinoma, sarcoma to lung d. bronchial ade ... | 1978 | 753577 |
| [time-related modification in bacterial etiology and mortality due to neonatal sepsis: study of 54 cases]. | | 1978 | 754165 |
| bacteriology and therapy of lung abscess in children. | the bacteriology and clinical findings of ten pediatric patients with lung abscess are presented. bacteriologic data were based on percutaneous transtracheal aspiration obtained before initiation of antimicrobial therapy. anaerobic bacteria were present in all ten patients; in nine they were mixed with aerobic bacteria. the most frequent isolates were peptostreptococcus (8), peptococcus (5), bacteroides melaninogenicus (6), and bacteroides fragilis (3). the aerobic isolates most frequently recov ... | 1979 | 758385 |
| three-day and ten-day chemotherapy for urinary tract infections in general practice. | the length of a course of antibiotic treatment for urinary tract infection varies with the habits of the prescriber. many patients do not complete a course of treatment once their symptoms have subsided. in uncomplicated urinary tract infection among women seen in general practice a three-day course of amoxycillin was as effective as a 10-day course of the same drug in the same dose. relief of symptoms was equal in both groups and bacteriuria was eliminated equally successfully in both regimens. ... | 1976 | 764915 |
| a biochemical approach to some problems of environmental pollution. | | 1975 | 765127 |
| [experimental respiratory infection of klebsiella pneumoniae in mice. i. conditions necessary for development of the infection]. | | 1975 | 765540 |
| [arsenic resistance of staphylococcus aureus and klebsiella pneumoniae]. | | 1975 | 765576 |
| [bactericidal activity of serum and chemotherapy in sensitive and resistant exciter (author's transl)]. | comparing examinations with ampicillin sensitive and resistant bacteria-strains show that the bactericidal activity of serum is dependent on the bacteria-strains, on the ampicillin sensitivity of the particular exciter and on the number of bacteria/ml (germ count). bactericide effect could always be obtained with sensitive strains as a result of additional chemotherapy. with several resistant strains a bactericide effect could not be obtained in this case the continuous optimal ampicillin addit ... | 1975 | 765704 |
| [indanyl carbenicillin in the treatment of urinary tract infections due to difficult urological organisms (author's transl)]. | fifty in-patients suffering from chronic urinary tract infections with underlying urological diseases received the oral carbenicillin preparation indanyl carbenicillin (short term carindacillin) for 10 days in a dosage of 1 g q.i.d. the therapy results were objectified by blood and urine tests performed prior to and after treatment. indanyl carbenicillin led to a sterile urine in nearly 60% of the patients; in about 85% of the cases the primary organism was eliminated. the drug was particularly ... | 1976 | 765706 |
| mutants of klebsiella pneumoniae resistant to several antibiotics. | | 1976 | 765837 |
| [urinary infections following bladder catheterization]. | the incidence and the prophylaxis of urinary tract infection following bladder catheterization have been studied in 142 patients admitted for voiding cystourethrography (vcu). 71 children received a prophylactic treatment of 2 mg/kg nitrofurantoin daily for 4 days, while 71 received no treatment following bladder catheterization. bacteriologic examination of the urine 4-9 days after catheterization showed significant bacteriuria in 5 untreated children. the germs responsible were e. coli, proteu ... | 1975 | 766175 |
| scleroma of the nose and pharynx. | scleroma of the respiratory tract was first recognized just over a century ago. the disease is endemic in a number of north african, central american and latin american countries. however, it has been only rarely seen in the united states. the progression of scleroma takes place through three stages. the first stage of rhinitis has an early catarrhal phase which progresses to one of atrophic rhinitis. the second stage is seen as a proliferative granulomatous growth which obliterates the nasal fo ... | 1976 | 766412 |
| [condition of microflora of the nasopharynx in immunization with live influenza vaccine for oral administration]. | the authors present data concerning the state of the microflora of the nasopharynx in the immunization of adults and schoolchildren with the living influenza vaccine for oral administration. during the vaccinal process there occurred qualitative changes in the microbial pattern of the nasopharynx and a reduction in the level of the salivary lysozyme. the most pronounced changes were seen after the first vaccination, when the seeding efficiency of the pathogenic staphylococcus the e. coli and the ... | 1975 | 766528 |
| extramembranous pregnancy with amniorrhoea. | a case of extramembranous pregnancy is reported. from about the 10th week of pregnancy there was an intermittent loss of liquor amnii, which from about the 25th week, became continuous. the infant was born alive in the 31st week, but died 15 days later because of the respiratory distress syndrome. the placenta was circumvallate with short, thick membranes unable to cover more than a small part of the infant. the course of the pregnancy and the prognosis of the infant are discussed on the base of ... | 1976 | 766556 |
| the regulation of carbohydrate metabolism in klebsiella aerogenes nctc 418 organisms, growing in chemostat culture. | klebsiella aerogenes nctc 418 was grown in chemostat cultures (d = 0.17 hr-1; ph 6.8;35 degrees c) that were, successively, carbon-, sulphate-, ammonia-, and phosphate-limited, and which contained as the sole carbon-substrate first glucose, then glycerol, mannitol and lactate. quantitative analyses of carbon-substrate used and products formed allowed carbon balances to be constructed and direct comparisons to be made of the efficiency of substrate utilzation. with all sixteen cultures, carbon re ... | 1975 | 766718 |
| massive pulmonary hemorrhage in neonatal infection. | of 35 newborn infants who died from an infection 19 had postmortem evidence of massive pulmonary hemorrhage. all but 1 of the 19 had evidence of antimortem formation of intravascular fibrin clots in lung tissue. seventeen infants had low platelet counts. of the 11 infants in whom coagulation studies were done, 8 had evidence of disseminated intravascular coagulation (dic) during life. vasculitis in the lungs, associated with fibrin clots and hemorrhages, was detected in two infants. it is postul ... | 1976 | 766937 |
| evaluation of an adenosine 5'-triphosphate assay as a screening method to detect significant bacteriuria. | the bioluminescent reaction of adenosine 5'-triphosphate (atp) with luciferin and luciferase has been used in conjunction with a sensitive photometer (lab-line's atp photometer) to detect significant bacteriuria in urine. this rapid method of screening urine specimens for bacteriuria was evaluated by using 348 urine specimens submitted to the clinical microbiology laboratory at the university of minnesota hospitals for routine culture using the calibrated loop-streak plate method. there was 89.4 ... | 1976 | 767357 |
| klebsiella l-forms: effect of growth as l-form on virulence of reverted klebsiella pneumoniae. | a strain of klebsiella pneumoniae virulent for mice was serially passaged in vitro as a penicillin-induced l-form. periodically, the l-form was reverted to the bacterial form by removal of penicillin, and the revertant was tested for virulence. virulence was gradually reduced, and after 109 passages the revertant was totally avirulent. virulence was not restored by 40 passages of the revertant through mouse peritoneum. the revertant grew less vigorously and did not infect mice when inoculated su ... | 1976 | 768382 |
| epidemics of nosocomial urinary tract infection caused by multiply resistant gram-negative bacilli: epidemiology and control. | | 1976 | 768384 |
| construction of a p plasmid carrying nitrogen fixation genes from klebsiella pneumoniae. | | 1976 | 768778 |
| expression of klebsiella nitrogen fixation genes (nif) in azotobacter. | | 1976 | 768779 |
| [clostridial and non-clostridial gas gangrene. apropos of 31 cases]. | | 1975 | 769461 |
| influence of maternal gut flora and colostral and cord serum antibodies on presence of escherichia coli in faeces of the newborn infant. | from 29 healthy newborn infants and their mothers faecal, serum and milk specimens were obtained on several occasions from one to nine weeks after delivery. predominant faecal e. coli were serotyped with regard to the o antigen and milk and serum were analysed for their content of e. coli o antibodies by the enzyme-linked immunosorbent assay. in five cases the babies acquired the same o serotype as was found in the stools of their mothers but in 12 out of 29 cases infant and mother never had any ... | 1976 | 769482 |
| tobramycin in chronic recurrent urinary tract infections. | a total of 32 adult patients of both sexes with chronic recurring urinary tract infections were treated with tobramycin in a daily dose of 1.2 mg/kg of body weight. they were randomly allocated to receive the drug at 8 or 12 hour intervals by intramuscular injection. the overall immediate disappearance of bacteriuria after therapy was 78.1 per cent; 15 days later, the cure rate dropped to 60 per cent. there was no difference between the two schedules tested. tolerance to tobramycin was excellent ... | 1976 | 769550 |
| antibiotic therapy in neonatal septicemia. | | 1976 | 769663 |
| in vitro studies of cefamandole. | cefamandole is a new cephalosporin antibiotic that was tested in vitro against 540 clinical isolates of gram-positive cocci and gram-negative bacilli. a concentration of 0.39 mug/ml inhibited 95% of the isolates of staphylococcus aureus. a concentration of 6.25 mug/ml inhibited over 90% of the isolates of proteus mirabilis and escherichia coli, 69% of the isolates of klebsiella pneumoniae, and 31% of the isolates of indole-positive proteus spp. and enterobacter spp. it was active against most ce ... | 1976 | 769679 |
| characterization of a replication mutant of the bacteriocinogenic plasmid clo df13. | in a previous paper (kool, a.j. and nijkamp, h.j.j. (1974) j. bacteriol. 120, 569--578) the isolation of a mutant of the bacteriocinogenic plasmid clo df13-rep3, has been described. it was observed that cells harbouring the wild type plasmid synthesize more plasmid dna cells harbouring the wild type plasmid. this paper deals with the characterization of the nature of this plasmid-specific mutation. the following properties of the clo df13-rep3 mutant plasmid could be observed: 1. the plasmid-spe ... | 1976 | 769825 |
| [postoperative bacterial endocarditis after cardiac prosthesis (author's transl)]. | the infection of an endocardial prosthesis, either valvular or septal patch, is a frequent and dangerous post-operative complication. eleven patients having postoperative endocarditis (9 on valve prosthesis and 2 on ventricular septal patch) are the subject of this paper. six of the 7 infected "early" had gram-negative bacteria in the blood cultures, while staphylococus aureus, streptococcus viridans and klebsiella pneumoniae were responsible for 3 of the 4 "late" infections. in 2 patients, one ... | 1975 | 770223 |
| tryptophan operon regulation in interspecific hybrids of enteric bacteria. | we examined tryptophan regulation in merodiploid hybrids in which a plasmid carrying the trp operon of escherichia was introduced into trp mutants of other enteric genera, or in which a plasmid carrying the trpr+ (repressor) gene of e. coli was transfered into fully constitutive trpr mutants of other genera. in these hybrids the trp operon of one species is controlled by the repressor of a different species. similar investigations were possible in transduction hybrids in which either the trp ope ... | 1976 | 770450 |
| kinetic studies of bacillus polymyxa nitrogenase. | nitrogenase from the facultative anaerobe bacillus polymxa was separated into its component proteins, which were recombined in the ratio that produced optimal specific activity (125 to 175 nmol of c2h2 reduced/min per mg of total protein). the apparent michaelis constants (km)for the magnesium adenosine triphosphate complex, reducible substrates azide, acetylene, and n2 and the nonphysiological electron donor hydrosulfite (s2o42-) were determined to be 0.7, 0.7, 0.2, 0.06, and 0.03 mm, respectiv ... | 1976 | 770451 |
| nonspecific resistance to infection induced in mice by a water-soluble adjuvant derived from mycobacterium smegmatis. | the effect of a nontoxic, water-soluble adjuvant (neo-wsa) from delipidated cells of mycobacterium smegmatis on the susceptibility of mice to infection with four challenge organisms was studied. an intravenous dose of 1 mg of neo-wsa per mouse 24 hr before challenge enhanced resistance to infection with a fungus (candida albicans), a gram-negative bacterium (klebsiella pneumoniae), and a gram-positive bacterium (streptococcus pneumoniae). protection by neo-wsa was not significant when the mice w ... | 1976 | 772130 |
| derivation and properties of f-prime factors in escherichia coli carrying nitrogen fixation genes from klebsiella pneumoniae. | a his+ nif+ escherichia coli k12, hfr strain (unf43) was constructed by an intergeneric mating between a klebsiella pneumoniae donor strain (hf3) and a his-hfr e. coli strain (sbi824) which transfers his as an early marker. an f-prime nif plasmid, fn39, carrying genes which correspond to the e. coli chromosomal region, metg gnd his shia, but excluding purf and arod, was isolated from unf43. translocation of carbenicillin resistance genes from a p-type r-factor, r68, to fn39 increased the stabili ... | 1976 | 772161 |
| nosocomial infections in a newborn intensive-care unit. results of forty-one months of surveillance. | we detected a 24.6 per cent nosocomial infection rate (222 infections in 138 infants) among 904 infants hospitalized for over 48 hours in a regional newborn intensive-care during 41 months of surveillance. surface infections accounted for 40.1 per cent of the total, pneumonia for 29.3 per cent, bacteremia for 14.0 per cent, surgical-wound infection for 8.1 per cent, urinary-tract infection for 4.5 per cent, and meningitis for 4.0 per cent. staphylococcus aureus (47.3 per cent) and gram-negative ... | 1976 | 772436 |
| klebsiella pneumonia facial fistula secondary to non-vital tooth. a case report. | | 1976 | 772504 |
| [pneumonia caused by klebsiella pneumoniae and complicated by pericarditis]. | | 1976 | 772636 |
| the prevalence of ampicillin, cephalosporin and sulphonamide resistance amongst urinary tract pathogens. | a total of 2,031 clinical isolates of gram negative bacilli was obtained from hospitals in 4 centres and these cultures were tested for resistance to ampicillin, cephazolin and sulphonamide. ampicillin and sulphonamide resistance in outpatients ranged from 15 to 28 per cent of e. coli strains and 4 to 11 per cent of proteus mirabilis strains. resistance to cephazolin in outpatients ranged from 0 to 3 per cent of e. coli and 0 to 6 per cent of proteus mirabilis. resistance patterns for e. coli, p ... | 1976 | 772807 |
| beta-lactamase resistance of cephazolin and other cephalosporins. | the turbidities of cultures of bacterial were monitored continuously at 37 degrees c. in a biophotometer. in the early phase of logarithmic growth, at approximately 2 x 10(7) organisms per ml., antibiotic was added. a strain of escherichia coli (e. coli) that was ampicillim-resistant, but cephaloridine-sensitive, produced beta-lactamase rapidly as shown by the breakdown of a chromogenic cephalosporin. the e. coli was lysed by cephaloridine 15 minutes after the addition of the antibiotic, but, ev ... | 1976 | 772808 |
| cephazolin: a comparison to ampicillin in respiratory and urinary infections with dosage regulation by a nomogram. | cephazolin sodium was shown to be as effective as ampicillin in the treatment of respiratory and urinary system infections in patients who were infected with susceptible organisms and had a much less troublesome side reaction rate of hypersensitivity type. in addition, it was found that predictable blood levels of cephazolin could be obtained in patients with renal failure when dosage was regulated according to a nomogram calculated from the patient's serum half-life based on clearance of creati ... | 1976 | 772809 |
| [pneumococci resistant to tetracycline and chloramphenicol as a cause of fatal pleuropneumonia]. | | 1976 | 772954 |
| [therapy of bacterial penumonias and their complications with and without pathogen isolation]. | | 1975 | 773205 |
| [microflora of the pus of lactation mastitis patients and its sensitivity to a series of antibiotics]. | the etiological picture of lactation mastitis and sensitivity of its causative agent to some antibiotics were studied. mostly microbial associations were isolated from the patients. pathogenic staphylococci typed mainly by the phages of group i predominated among the isolates. in addition the strains of proteus, pseudomonas, e. coli and others were isolated from the pus of the mastitis cases. sensitivity of the microflora to some antibiotics was studied. it was found that most of the causative a ... | 1975 | 773286 |
| the action of iron on local klebsiella infection of the skin of the guinea-pig and its relation to the decisive period in primary infective lesions. | the infectivity of 16 strains of klebsiella spp. and its modification by systemic and local ferric iron were tested in the skin of the guinea-pig. the in vivo proliferation of 11 strains was enhanced in varying degrees by fe+++ (e + strains); 5 strains (eo) were not enhanceable even by large doses of fe+++. of 10 strains examined in detail, 6 were e + and 4 were e0. guinea-pig and human sera were consistently bacteriostatic for e + strains and bactericidal for eo strains. both fe+++ and microbia ... | 1976 | 773402 |
| reactivation by a bacterial acetate: enzyme ligase of plant glyoxysomal isocitrate lyase. | | 1975 | 773688 |
| contamination of the small intestine by enterotoxigenic coliform bacteria among the rural population of haiti. | coliform bacteria were isolated by either aerobic or anaerobic culture techniques from aspirates of the proximal small intestine of 4 of 5 haitians with tropical sprue, but not from any of 10 well nourished haitians who had milder gastrointestinal complaints and abnormalities. klebsiella (klebsiella pneumoniae and klebsiella ozaenae) was cultured from the jejunal aspirates of 2 sprue patients and escherichiae coli from the other 2. fifteen colonies of coliform bacteria cultured from each aspirat ... | 1976 | 773737 |
| a clinical study of primary infection on the lungs and pleura by friedlander's bacillus. | | 1976 | 773813 |
| failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. | in vitro and in vivo responses to lipopolysaccharide (lps) and various other bacterial immunostimulants were compared in c3h/he low-responder mice. the principal findings were as follows. (i) their splenic lymphocytes were stimulated by various gram-negative mitogens such as an escherichia coli peptidoglycan, a detoxified derivative of lps, and even endotoxins extracted by trichloroacetic acid that are known to contain protein; spleen cells of these mice were also transformed by two other b-cell ... | 1976 | 773822 |
| subunit and chemical composition of citrate lyase from klebsiella pneumoniae. | citrate lyase from klebsiella pneumoniae (previously called klebsiella aerogenes) is shown by amino acid sequencing techniques to contain equimolar amounts of three nonidentical subunits. together with the molecular weight of the enzyme, this finding is interpreted to indicate that there are 6 mol of each of these subunits per mol of native enzyme. a partial amino acid sequence of each of the three subunits is presented. the pure enzyme with a specific activity of 73 units/mg of dry protein has ... | 1976 | 773936 |
| [revaluation of gentamicin in laboratory and clinical studies (author's transl)]. | the mic of gentamicin and other antibiotics against clinical isolates was determined, and the following sensitivity distribution was obtained. a) against 54 strains of staphylococcus aureus, gm had the lowest mic, followed by tob, dkb, bb-k8 in order. the distribution range of 0.1-6.25 mug/ml was noted with gm. the peak of mic was 1.56 mug/ml. b) against 54 strains of e. coli, the lowest mic was obtained with gm, and 53 strains (98%) were in the range of 0.4-6.25 mug/ml. the peak of mic was 3.12 ... | 1976 | 775143 |
| bacterial mastitis in guinea pigs. | necropsy of 37 guinea pigs revealed mastitis to be the primary cause of death in 70% of these animals. epidemiologic study failed to establish correlation between age, parity, or litter size and the onset of mastitis. the disease did not appear to be contagious. although mastitis frequently developed during lactation, survivability of offspring was unaffected. the agent most consistently isolated from affected mammary glands was escherichia coli (17 of 37). other isolates in decreasing order of ... | 1976 | 775191 |
| antimicrobial agents from higher plants. additional alkaloids and antimicrobial agents from thalictrum rugosum. | further study of mother-liquors from ethanolic extracts of thalictrum rugosum resulted in the identification or partial characterization of 10 alkaloids, bringing the total to 17 characterized in our work on this plant. five of the new alkaloids were active in vitro against microorganisms. structures, based upon spectroscopic properties and chemical transformations, are proposed for a new bisbenzylisoquinoline alkaloid named thalrugosaminine, and a protopine alkaloid named protothalipine. a phen ... | 1976 | 775233 |
| characterization of two h2s-producing, multiple drug-resistant isolates of escherichia coli from clinical urine specimens. | two h2s producing, multiple drug-resistant variants of escherichia coli were isolated from clinical urine specimens. both isolates transferred, eleven resistance determinants to recipient strains of e. coli k 12 and nine r-determinants to klebsiella pneumoniae recipients; in no instance was transfer of the 'curing'-refractory h2s marker demonstrable. | 1975 | 775411 |
| transferable and non-transferable drug resistance in enteric bacteria from hospital and from general practice. | drug resistance to 8 different antibiotics in enterobacteriaceae isolated from different hospitals and two groups of general practitioners was studied. escherichia coli dominated among the 632 strains investigated. drug resistance was found in 62% of the 512 hospital strains and in 38% of the 120 strains from general practice. multiple resistance was common especially in strains from hospital. r factors was found in 23% of the 317 drug-resistant strains from hospital and in 11% of the 46 drug-re ... | 1976 | 775619 |
| factors affecting the frequency infection in renal transplant recipients. | a retrospective review of 149 patients receiving 162 renal transplants showed that 83% of these patients developed one or more infections during a follow-up period averaging one year. in 32 (73%) of 44 deaths, infection was an important contributing cause. in only four (9%) of the deaths were the patients free of infection at the time of death. the klebsiella-enterobacter group was the most common agent causing pneumonitis and sepsis. cryptococcus neoformans caused seven of 11 cases of meningiti ... | 1976 | 776110 |
| [localization of antigens in common (cross-reacting) with neisseria perflava and klebsiella pneumoniae in the tissues of the human bronchopulmonary tract]. | an attempt was made of detecting antigenic similarity beyween the fraction of microsomes of the tissues of human broncho-pulmonary apparatus and the cells of microbes of human respiratory tract. cross reactions of antimocrosomal sera were studied in the complement fixation test with neisseria perflava and klebsiella pneumoniae. fixation of antibacterial antibodies and antibodies against the microsomal fraction of the lung tissues was studied on the sections of the lung tissues ahd human bronchi. ... | 1976 | 776254 |
| donovanosis in papua new guinea. | clinical and epidemiological observations on 87 cases of donovanosis seen at port moresby general hospital are presented, with detailed reports of three cases in which the disease was more severe. the circumstances of infection described were consistent with venereal transmission. chloramphenicol and gentamicin were effective in curing the disease, while streptomycin was found to be ineffective in a number of cases tested. complement-fixation tests with donovania antigen revealed the presence of ... | 1976 | 776356 |
| study on the efficiency of four procedures for enumerating coliforms in water. | four coliform estimation procedures were compared as to their ability to enumerate coliform bacteria (oxidase-negative lactose fermenters) from sewage, effluent, and various fresh waters in the lower great lakes region of canada. two of the procedures used and which are cited in the american public health association (apha) standard methods were a most probable number (mpn) technique using lauryltryptose broth (lst) and brilliant green bile 2% broth (bgb), and a membrane filtration (mf) techniqu ... | 1976 | 776372 |
| activation of the complement system during infections due to gram-negative bacteria. | | 1976 | 776471 |
| relationship between antibiotic consumption and frequency of antibiotic resistance of four pathogens--a seven-year survey. | | 1976 | 776921 |
| a new serotyping method for klebsiella species: development of the technique. | a new serotyping method for klebsiella species using indirect immunofluorescence is described. nonspecific fluorescence has been minimized by carrying out the capsular antigen-antibody reaction at ph 9.0. commercial antisera have been tested with the 72 antigenic types of klebsiella, and appropriate dilutions of each pool and specific antisera have been proposed for use in routine typing. dilutions were chosen to allow strong fluorescence with each type and its specific antiserum and minimal flu ... | 1976 | 777042 |
| a new serotyping method for klebsiella species: evaluation of the technique. | a new indirect fluorescent typing method for klebsiella species is compared with an established method, capsular swelling. the fluorescent antibody (fa) technique was tested with standards and unknowns, and the results were checked by capsular swelling. several unknowns were sent away for confirmation of typing, by capsular swelling. the fa method was also tried by a technician in the routine department for blind identification of standards. fluorescence typing gives close correlation with the e ... | 1976 | 777043 |
| induction of resistance in staphylococcus aureus and klebsiella pneumoniae by exposure to cephalothin and cefoxitin. | six strains each of staphylococcus aureus and klebsiella pneumoniae were exposed to subinhibitory, but serially incremental, concentrations of cephalothin and cefoxitin in a totally defined liquid culture medium. after exposure to cephalothin, the level of resistance to both drugs increased; the gain was greater against cephalothin and among the strains of k. pneumoniae. after exposure to cefoxitin, resistance to both drugs developed; this resistance was greater against cefoxitin and among the s ... | 1976 | 778303 |
| influence of atmospheric oxygen concentration on acetylene reduction and efficiency of nitrogen fixation in intact klebsiella pneumoniae. | oxygen-limited (n2-fixing) chemostat cultures of klebsiella pneumoniae supplied with a n-free medium were established by introducing low atmospheric o2 concentrations into the gas supply of anaerobic glucose-limited n2-fixing chemostat cultures; the molar growth yield for glucose and the efficiency of n2 fixation (mug n fixed/mg glucose consumed) were increased (by up to 82%) from the anaerobic values. acetylene-reducing activity was inhibited reversibly by o2 in samples from o2-limited and anae ... | 1976 | 778326 |
| relationship of structure to function in bacterial endotoxins: serologically cross-reactive components and their effect on protection of mice against some gram-negative infections. | rabbit antisera were prepared against the heptoseless re mutants, salmonella minnesota r595 and s. typhimurium sli102, as well as against purified r595 glycolipid coated on autologous erythrocytes. the antisera cross-reacted with the endotoxic glycolipids extracted from re mutants of various bacterial strains, including s. minnesota r595, s. typhimurium sli102, escherichia coli d3im4, e. coli d2if2 and e. coli f515, as shown by passive haemagglutination and gel diffusion tests. the anti-re sera ... | 1976 | 778329 |
| the importance of prolonged incubation for the synthesis of dimethylnitrosamine by enterobacteria. | tests with 140 strains representing escherichia coli, klebsiella aerogenes, k. ozaenae, proteus mirabilis, p. vulgaris, p. rettgeri and p. morganii in a defined medium supplemented with 0-09m dimethylamine (dma) and 0-1m potassium nitrate showed that at least 89% of the 136 strains able to reduce nitrates produced up to 9mm dimethylnitrosamine (dmn) in 70h at 37 degrees c. four nitratase-negative strains produced dmn from dma in the presence of sodium nitrate. prolonged incubation was the most i ... | 1976 | 778390 |
| the influence of antibiotic treatment on resistance patterns of coliform bacilli in childhood urinary-tract infection. | the occurrence of coliform bacilli carrying resistance-transfer factors (r factors) in children was studied. the frequency of r+ coliform bacilli as causes of urinary-tract infection acquired outside hospital was found to be similar to that in adults from the same geographical area and in the same years. the frequency of r+ coliform bacilli in the faeces in our children was also similar to that in the adult population, and oral chemotherapy produced similar changes in the faecal flora. | 1976 | 778392 |
| [studies on the intravenous administration of sulbenicillin (author's transl)]. | basic and clinical investigation on the intravenous administration of sulbenicillin in moderate dose (510g daily) was carried out to evaluate its clinical effect in systemic infections due to gram-negative bacilli. the following results were obtained. (1) in human subjects received 5 g intravenous drip infusion, the peak blood levels were found at the end of infusion. in 6 cases with normal renal function (ccr greater than or equal to 70ml/min.) the peak blood level was 181 mcg/ml on the average ... | 1976 | 778428 |
| [experimental studies of chronic rheumatoid arthritis--experimental models of arthritis]. | | 1976 | 778442 |
| therapy of infections in neutropenic patients: results with gentamicin in combination with cephalothin or chloramphenicol. | gentamicin in combination with cephalothin (gent-ceph) or with chloramphenicol (gent-chloro) was utilized in the treatment of 55 infections occurring in 49 cancer patients. responses were obtained in 78% of the infections treated with gent-ceph and in 64% of those treated with gent-chloro. pneumonia and septicemia were the most common infections in this study. among the cases of penumonia, 64% responded to gent-ceph and 67% to gent-chloro. among the cases of septicemia, 88% responded to gent-cep ... | 1976 | 778574 |
| [treatment with gentamicin in 22 cases of epidemic acute enteritis due to gram-negative germs in a neonatal intensive care department]. | | 1975 | 778577 |
| inhibition by acetylene of conventional hydrogenase in nitrogen-fixing bacteria. | | 1976 | 778640 |
| the resistance of 150 klebsiella and e. coli strains isolated from patients suffering from bacteriaemia. | | 1976 | 779005 |
| [resistance to beta-lactam antibiotics and aminoglycosides in gram negative bacteria. 1. molecular and genetic characterization of r-factors (author's transl)]. | with frequent use of aminoglycoside antimicrobials and beta-lactam antibiotics in hospitals in the last few years, the number of bacterial strains resistant to these chemotherapeutics increased. lately, strains of e. coli, klebsiella, enterobacter, serratia, proteus and pseudomonas resistant to many antimicrobials (ampicillin, carbenicillin, cephalothin, chloramphenicol, gentamycin, tobramycin, sisomycin, neomycin, paromomycin, kanamycin, streptomycin, spectinomycin, tetracycline, sulphonamides) ... | 1976 | 779353 |
| [resistance to beta-lactam antibiotics and aminoglycosides in gram negative bacteria. 2. mechanism of resistance (author's transl)]. | in a preceding paper the genetics of resistance of 2 representative strains exhibiting resistance to beta-lactam antibiotics (ampicillin, catbenicillin, cephalothin) to aminoglycosides (kanamycin, neomycin, paromomycin, gentamycin, sisomycin, tobramycin, streptomycin, spectinomycin) and further antimicrobials (tetracycline, chloramphenicol, suphonamides) were described. this paper reports about the mechanism of resistance to beta-lactam antibiotics and aminoglycosides in these strains. enzymatic ... | 1976 | 779354 |
| effect of antimicrobial soap containing chlorhexidine on the microbial flora of skin. | the qualitative and semiquantitative changes in the aerobic microbial flora of normal skin with the prolonged use of a chlorhexidine scrub (6 months) were investigated. more samples in the chlorhexidine scrub group had gram-negative bacilli in their axilla (63 of 96, 66%) and groin (36 of 96, 38%) than the controls (32 of 66, 49%, for axilla and 7 of 66, 11%, for groin; p = 0.01). klebsiella and enterobacter were the predominant organisms in the control and chlorhexidine groups, respectively. th ... | 1976 | 779648 |
| [practical importance of quantitative bacteriology in pneumology. preliminary studies]. | some ascertained the utility of the quantitative bacteriology in pneumology especially for the diagnosis of acute bronchopulmonary infections. miles and mizra technique lightly changed as analytically here described is suitable for counts of viable bacteria in sputum after liquefaction by n-acetyl-l-cisteine. some researches prove that the technique is convenient for the control of chronic bronchopulmonary infections too with some restrictions. quantitative tests are important to ascertain aetio ... | 1975 | 779672 |
| the molybdenum--iron protein of klebsiella pneumoniae nitrogenase. evidence for non-identical subunits from peptide 'mapping'. | the molybdenum- and iron-containing protein components of nitrogenase purified from klebsiella pneumoniae, azotobacter vinelandii, azotobacter chroococcum and rhizobium japonicum bacteroids all gave either one or two protein-staining bands after sodium dodecyl sulphate/polyacrylamide-gel electrophoresis, depending on the commercial brand of sodium dodecyl sulphate used. the single band obtained with k. pneumoniae mo-fe protein when some commercial brands of sodium dodecyl sulphate were used in t ... | 1976 | 779772 |
| [in vitro effect of cephacetril and colistin combinations on klebsiella pneumoniae and proteus strains (author's transl)]. | in 14 out of 43 klebsiella pneumoniae strains (33%) the combination cephacetril-colistin showed a synergistic, in 11 strains (25%) an additive effect. in proteus strains no synergistic action was found. the combination was more likely to be synergistic or additive in strains requiring higher minimal inhibitory concentrations of cephacetril and colistin. most highly resistant klebsiella pneumoniae strains were synergistically inhibited by concentrations of both drugs, which can easily be obtained ... | 1976 | 779799 |
| antibacterial activity of ribostamycin on enterobacteriaceae. | the study of the inhibitory activity of ribostamvcin (vistamycin), an antibiotic derived from streptomyces ribosidificus, on 161 strains of gram-negative bacilli shows that the antibacterial spectrum of this antibiotic is identical to that of kanamycin. if controlled clinical studies confirm that ribostamycin is less toxic than kanamycin on the otovestibular system, this antibiotic will constitute a real therapeutic advance. | 1976 | 779802 |
| stomatitis in patients on anti-neoplastic drugs: report of case and management. | | 1976 | 779896 |
| potentiating effects of manganese dioxide on experimental respiratory infections. | | 1976 | 780104 |
| bacteriophage ec1-resistant mutants of enteric bacteria. | | 1976 | 781186 |
| shigella dysentery with secondary klebsiella sepsis. | | 1976 | 781203 |
| semisynthetic cephalosporins. synthesis and structure-activity relationships of 7-sulfonylacetamido-3-cephem-4-carboxylic acids. | the synthesis and in vitro and in vivo activities of a series of 7-sulfonylacetamido-3-cephem-4-carboxylic acids with acetoxymethyl or heterocyclic thiomethyl substituents at the 3 position are described. lengthening the alkyl chain attached to the sulfonyl group increased gram-positive activity but the effect on gram-negative activity was variable. other structural changes on the 7-acyl side chain resulted in only minor changes in vitro activity. the protective effectiveness in infected mice g ... | 1976 | 781242 |
| imidazo(1,2-c)pyrimidine nucleosides. synthesis and biological evaluation of certain 1-(beta-d-arabinofuranosyl)imidazo(1,2-c)pyrimidines. | the first chemical syntheses of the arabinosylhypoxanthine and arabinosylguanine analogues of the imidazo-[1,2-c]pyrimsdine series are described. condensation of trimethylsilyl-7-chloroimidazo[1,2-c]pyrimidin-5-one (1) with 2,3,5-tri-o-benzyl-alpha-d-arabinofuranosyl chloride (2) gave 7-chloro-1-(2,3,5-tri-o-benzyl-beta-arabinofuranosyl)imidazo[1,2-c]pyrimidin-5-one (3) which on catalytic dehalogenation furnished 1-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl)imidazo[1,2-c]pyrimidin-5-one (4). am ... | 1976 | 781243 |
| [bacteriology of juvenile urinary tract infections]. | | 1975 | 781508 |
| cutaneous protothecosis in a patient receiving immunosuppressive therapy. | a 30-year-old recipient of a renal transplant, who was receiving immunosuppressive therapy, developed cutaneous abscesses from which an organism of the genus prototheca was cultured. the patient died of klebsiella septicemia. at the time of death, pure cultures of prototheca and candida organisms were grown from separate skin lesions. prototheca is a genus of achloric algae. cultural, microscopical, and staining characteristics separate these organisms from the yeast and fungi. cutaneous prototh ... | 1976 | 782362 |
| [immobilized antibodies: a possible technic for the epidemiological study of antibiotic resistant bacteria]. | an antibody specific to a cephalosporinase responsible for the resistance of bacteria to cephalosporines has been immobilized on agarose beads by the iminocarbonate method. the resin thus obtained has been studied at a biospecific point of view. its high thermostability is also demonstrated. this biospecific resin allows the performance of epidemiologic experiments of bacteria resistant to beta lactamines. | 1976 | 782563 |
| [localization in cells of neisseria perflava and klebsiella pneumoniae of antigens in common (cross-reacting) with tissues of the human bronchopulmonary apparatus]. | a study was made of localization in the cells of neisseria perflava and klebsiella pneumoniae of antigens common with the tissues of the human broncho-pulmonary apparatus. a study was made of cross reactions of some structures of neisseria perflava and klebsiella pneumoniae cells (capsule, walls, cytoplasmic structure fraction, hyaloplasm) in the complement fixation test with antilung sera. antigens cross reacting with the antilung sera were localized not only in the surface structures (walls) o ... | 1976 | 782606 |
| co-trimoxazole in prevention of bacteriuria after prostatectomy. | in a prospective, double-blind trial prophylactic cotrimoxazole produced a highly significant reduction in the incidence of bacteriuria after prostatectomy. only two out of 38 patients who received the drug developed bacteriuria compared with 19 out of 36 patients on placebo. klebsiella-enterobacter spp and coagulase-negative staphylococci were responsible for most infections. although co-trimoxazole prophylaxis is obviously effective, widespread use might increase the incidence of bacterial res ... | 1976 | 782651 |
| [treatment of peritonitis within the scope septic shock with antibiotics]. | | 1976 | 782801 |
| [sisomicin versus gentamicin. a comparison of antibacterial and pharmacokinetic properties (author's transl)]. | in a comparison of the antibacterial in-vitro activity of sisomicin, gentamicin, and tobramycine, sisomicin showed a higher activity against e. coli, indole-positive proteus spp. and organisms of the klebsiella-enterobacter-serratia group, whereas tobramycine was superior against pseudomonas spp. however, the differences in activity between sisomicin and gentamicin were only within one step of dilution which is hardly sufficient to guarantee a basic superiority of one or the other preparation fo ... | 1976 | 782808 |
| [evaluation of diagnostic parameters in chronic recurrent urinary tract infection in children. iii. pyuria, hematuria, and proteinuria (author's transl)]. | pyuria, proteinuria and haematuria have been shown to be unreliable parameters for the diagnosis of bacteriuria in 171 children with 455 recurrences of chronic urinary tract infection. bacteriuria caused haematuria in 5%, proteinuria in 18% and even pyuria in only 47% of all instances. pyuria has been also found in 11% of sterile urines. the incidence of pyuria increases with the age of the children and depends on the type of the organisms, but the latter was true mainly in children with obstruc ... | 1976 | 782812 |
| infections in the surgical departments of a teaching hospital in jerusalem. | surveillance of hospital-associated infections at the hadassah university hospital has been carried out since 1970. criteria for infection were defined and were monitored by trained nurse-epidemiologists, with the cooperation of the surgical staff. this report deals with the results of a prospective study of infections present on admission, and those acquired during hospitalization, in six surgical departments between january 1972 and june 1973. of the 7,339 patients discharged, 7.5% acquired an ... | 1976 | 783080 |
| microbial metabolism of amino alcohols. ethanolamine catabolism mediated by coenzyme b12-dependent ethanolamine ammonia-lyase in escherichia coli and klebsiella aerogenes. | | 1976 | 784902 |
| the apparent atp requirement for nitrogen fixation in growing klebsiella pneumoniae. | the apparent atp requirement for n2 fixation in klebsiella pneumoniae was high (the atp/n2 molar ratio was 29 when estimated in anaerobic glucose-limited chemostat cultures) compared with that determined previously in azotobacter chroococcum and in clostridium pasteurianum. the high value was probably not due to unfavourable temperature, phosphate concentration or ph. the apparent atp requirement for n2 fixation was probably no lower in 02-limited chemostat cultures than in anaerobic glucose-lim ... | 1976 | 784906 |
| gram-negative bacillary meningitis therapy. polyradiculitis following intralumbar aminoglycoside administration. | gram-negative bacillary meningitis is a serious threat to patients with head trauma or altered immune systems, or those who have had neurosurgical procedures. the aminoglycoside antibiotics administered systemically and into the cerebrospinal fluid (csf) have proved useful in the treatment of these infections. intralumbar and parenteral gentamicin sulfate and tobramycin sulfate were administered to an acromegalic woman with klebsiella meningitis. she had objective evidence of adhesive arachnoidi ... | 1976 | 785039 |